ORF name	Slide_Ave_Signal(before GST)	Pro_pro interaction	Known substrate	localization	Essentiality	MIPS annotation	Common name	SGD annotation
YMR184W	2453.88	0	0	cytoplasm	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YMR081C	2191.34	0	0	cytoplasm	Non-essen Genes	-	ISF1	cellular_component unknown	molecular_function unknown	aerobic respiration
YKL093W	10913.97	0	0	cytoplasm	Non-essen Genes	-	MBR1	cellular_component unknown	molecular_function unknown	aerobic respiration
YFR014C	6999.57	0	0	cytoplasm	-	-	CMK1	cytoplasm	calmodulin-dependent protein kinase I	protein amino acid phosphorylation	signal transduction
YOR334W	1613.18	0	0	mitochondrion	Non-essen Genes	-	MRS2	mitochondrial inner membrane	magnesium ion transporter	magnesium ion transporter	magnesium ion transporter	mRNA splicing	mitochondrial magnesium ion transport	mitochondrial magnesium ion transport	mitochondrial magnesium ion transport
YLR410W	2213.13	0	0	cytoplasm	Non-essen Genes	-	VIP1	cellular_component unknown	molecular_function unknown	actin cytoskeleton organization and biogenesis
YJR001W	2184.03	0	0	cytoplasm	Non-essen Genes	121	AVT1	vacuole	neutral amino acid transporter	neutral amino acid transporter	neutral amino acid transporter	neutral amino acid transport	neutral amino acid transport
YKL064W	3947.84	0	0	Ambiguous	Non-essen Genes	-	MNR2	membrane	magnesium ion transporter	magnesium ion transport
YFR017C	7392.5	0	0	cytoplasm	Non-essen Genes	-		molecular_function unknown	biological_process unknown
YPL240C	4903.71	0	0	cytoplasm	Non-essen Genes	101.31	HSP82	cytoplasm	cation-transporting ATPase	chaperonin ATPase	heat shock protein	protein folding	response to stress
YHL020C	3562.09	0	0	nuclear periphery	Non-essen Genes	-	OPI1	nucleus	transcription co-repressor	negative regulation of transcription from Pol II promoter	phospholipid biosynthesis
YDR023W	2438.38	0	0	cytoplasm	Essentail Genes	-	SES1	cytoplasm	serine-tRNA ligase	amino acid activation
YOR187W	3731.49	0	0	mitochondrion	Non-essen Genes	61.31	TUF1	mitochondrial matrix	mitochondrial ribosome	translation elongation factor	translational elongation
YAR018C	3177.79	0	0	mitochondrion	Non-essen Genes	161.41.51	KIN3	cellular_component unknown	protein kinase	chromosome segregation
YKR072C	4146.7	0	0	cytoplasm	Non-essen Genes	-	SIS2	cytoplasm	cytoplasm	nucleus	nucleus	protein phosphatase inhibitor	G1/S transition of mitotic cell cycle	regulation of mitotic cell cycle	salinity response	salinity response
YOR068C	3259.35	0	0	cytoplasm	Non-essen Genes	-	VAM10	cellular_component unknown	molecular_function unknown	biological_process unknown
YPL146C	2424.99	0	0	nucleus	Essentail Genes	-		nucleolus	nucleus	molecular_function unknown	biological_process unknown
YLR443W	3510.3	0	0	nucleus	Non-essen Genes	-	ECM7	cellular_component unknown	molecular_function unknown	cell wall organization and biogenesis
YDR379W	3258.31	0	0	cytoplasm	Non-essen Genes	-	RGA2	intracellular	Rho GTPase activator	signal transducer	actin filament organization	apical bud growth	establishment of cell polarity (sensu Saccharomyces)	invasive growth	isotropic bud growth	pseudohyphal growth	signal transduction during conjugation with cellular fusion	small GTPase mediated signal transduction
YHR182W	2847.47	0	0	cell periphery && cytoplasm	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YLR113W	3839.9	0	0	cytoplasm	Non-essen Genes	161.31.21	HOG1	cytoplasm	nucleus	MAP kinase	hyperosmotic response	protein amino acid phosphorylation
YHR168W	2243.44	0	0	cytoplasm	Non-essen Genes	61.99		cellular_component unknown	molecular_function unknown	biological_process unknown
YML013W	2957.74	0	0	ER	Non-essen Genes	-	SEL1	cellular_component unknown	molecular_function unknown	protein secretion
YEL065W	2981.29	0	0	vacuole	Non-essen Genes	121	SIT1	cytoplasmic vesicle	endosome	siderochrome-iron (ferrioxamine) uptake transporter	siderochrome-iron (ferrioxamine) uptake transporter	iron ion homeostasis	iron ion homeostasis	iron-siderochrome transport
YKL114C	2504.59	0	0	mitochondrion && nucleus	Non-essen Genes	-	APN1	mitochondrion	nucleus	DNA-(apurinic or apyrimidinic site) lyase	DNA-(apurinic or apyrimidinic site) lyase	DNA repair
YHR158C	1987.97	0	0	cell periphery && bud neck && Ambiguous	Non-essen Genes	-	KEL1	bud neck	bud tip	cytoplasm	shmoo tip	molecular_function unknown	cellular morphogenesis	cytogamy	cytogamy	cytogamy	plasma membrane fusion	regulation of cell shape
YBR142W	3443.19	0	0	nucleolus && nucleus	Essentail Genes	-	MAK5	nucleus	ATP dependent RNA helicase	rRNA processing	ribosomal large subunit assembly and maintenance
YNR006W	3527.24	0	0	endosome	Non-essen Genes	-	VPS27	endosome	protein binding	protein-Golgi retention
YDR285W	2653.61	0	0	endosome	Non-essen Genes	-	ZIP1	synaptonemal complex	molecular_function unknown	meiosis	synapsis
YMR223W	4695.4	0	0	nucleus	Non-essen Genes	191.51	UBP8	SAGA complex	ubiquitin-specific protease	protein deubiquitination
YNR042W	3670.52	0	0	nucleus	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YKL157W	3121.12	0	0	mitochondrion && cytoplasm	Non-essen Genes	151	APE2	cytoplasm	periplasmic space (sensu Fungi)	leucyl aminopeptidase	peptide metabolism
YJR014W	2952.76	0	0	cytoplasm	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YPL056C	4555.69	0	0	cytoplasm	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YOR134W	4147.93	0	0	cytoplasm	Non-essen Genes	81.99	BAG7	intracellular	Rho GTPase activator	signal transducer	small GTPase mediated signal transduction
YHR028C	2867.06	0	0	cytoplasm	Non-essen Genes	-	DAP2	vacuolar membrane (sensu Fungi)	dipeptidyl-peptidase and tripeptidyl-peptidase	protein processing
YIL033C	29817.76	1	0	cytoplasm && nucleus	Non-essen Genes	-	BCY1	cytoplasm	nucleus	cAMP-dependent protein kinase inhibitor	pseudohyphal growth	response to heat	response to stress	signal transduction
YOL121C	2390.05	0	0	cytoplasm	Non-essen Genes	-	RPS19A	cytosolic small ribosomal subunit (sensu Eukarya)	structural constituent of ribosome	protein biosynthesis
YGL075C	3224.93	0	0	spindle pole	Essentail Genes	-	MPS2	nuclear membrane	spindle pole body	structural constituent of cytoskeleton	mitotic anaphase	spindle pole body duplication (sensu Saccharomyces)
YOR163W	4481.98	0	0	cytoplasm && nucleus	Non-essen Genes	-	DDP1	cellular_component unknown	diphosphoinositol-polyphosphate diphosphatase	diadenosine polyphosphate metabolism
YOL052C	3122.93	0	0	cytoplasm && nucleus	Non-essen Genes	-	SPE2	cellular_component unknown	adenosylmethionine decarboxylase	pantothenate biosynthesis
YDR068W	3633.39	0	0	cytoplasm	Non-essen Genes	-	DOS2	cellular_component unknown	molecular_function unknown	biological_process unknown
YGL184C	2780.1	0	0	cytoplasm && nucleus	Non-essen Genes	-	STR3	peroxisome	cystathionine beta-lyase	cystathionine beta-lyase	methionine biosynthesis
YGR285C	2326.93	0	0	cytoplasm	Non-essen Genes	101.61	ZUO1	cytoplasm	cytosol	ribosome	chaperone	protein folding
YDR443C	3055.42	0	0	cytoplasm && nucleus	Non-essen Genes	141.21.21	SSN2	transcription factor complex	general RNA polymerase II transcription factor	negative regulation of transcription from Pol II promoter
YNL117W	4047.18	0	0	cytoplasm && nucleus	Non-essen Genes	-	MLS1	cytoplasm	peroxisomal matrix	malate synthase	glyoxylate cycle
YER168C	2943.88	0	0	cytoplasm	Essentail Genes	-	CCA1	cytoplasm	mitochondrial matrix	nucleus	tRNA adenylyltransferase	tRNA modification
YDL081C	2417.26	0	0	cytoplasm	Non-essen Genes	-	RPP1A	cytosolic large ribosomal subunit (sensu Eukarya)	structural constituent of ribosome	protein biosynthesis	translational elongation
YNL245C	2717.64	0	0	nucleus	Essentail Genes	-	CWC25	cellular_component unknown	molecular_function unknown	biological_process unknown
YOR266W	3390.14	0	0	mitochondrion	Non-essen Genes	-	PNT1	mitochondrial inner membrane	molecular_function unknown	inner mitochondrial membrane organization and biogenesis
YHR185C	2092.21	0	0	mitochondrion	Non-essen Genes	-	PFS1	cellular_component unknown	molecular_function unknown	spore wall assembly (sensu Fungi)
YPL166W	2986.92	0	0	punctate composite && cytoplasm && nucleus	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YLR043C	2589.61	0	0	cytoplasm && nucleus	Non-essen Genes	-	TRX1	cytosol	vacuole (sensu Fungi)	thiol-disulfide exchange intermediate	DNA dependent DNA replication	regulation of redox homeostasis	response to oxidative stress	vacuole fusion (non-autophagic)	vacuole inheritance
YPL138C	2451.89	0	0	nucleus	Non-essen Genes	-	SPP1	chromatin	chromatin binding	histone-lysine N-methyltransferase	transcriptional activator	chromatin silencing at telomere	histone methylation	"regulation of transcription, DNA-dependent"
YDR237W	2818.28	0	0	nucleus	Non-essen Genes	-	MRPL7	mitochondrial large ribosomal subunit	structural constituent of ribosome	protein biosynthesis
YDL165W	3156.5	0	0	cytoplasm	Essentail Genes	-	CDC36	CCR4-NOT core complex	cytoplasm	nucleus	3'-5' exoribonuclease	negative regulation of transcription from Pol II promoter	poly(A) tail shortening	regulation of cell cycle	regulation of transcription from Pol II promoter	response to pheromone during conjugation with cellular fusion
YBR298C-A	3219.53	0	0	cytoplasm	-	-	MAL31	membrane fraction	general alpha-glucoside:hydrogen symporter	alpha-glucoside transport
YDR382W	2643.71	0	0	cytoplasm	Non-essen Genes	-	RPP2B	cytosolic large ribosomal subunit (sensu Eukarya)	structural constituent of ribosome	protein biosynthesis	translational elongation
YLR044C	6218.86	0	0	cytoplasm && nucleus && Ambiguous	Non-essen Genes	-	PDC1	cellular_component unknown	pyruvate decarboxylase	ethanol fermentation	pyruvate metabolism
YLR440C	4770.75	0	0	ER	Essentail Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YHR157W	18033.48	0	0	ER	Non-essen Genes	-	REC104	cellular_component unknown	molecular_function unknown	meiotic DNA double-strand break formation	meiotic recombination
YBR059C	5318.88	0	0	cell periphery && bud neck && cytoplasm	Non-essen Genes	161.41.41	AKL1	cellular_component unknown	protein kinase	biological_process unknown
YDR158W	3232.01	0	0	cytoplasm && nucleus	Non-essen Genes	-	HOM2	cellular_component unknown	aspartate-semialdehyde dehydrogenase	methionine metabolism	threonine metabolism
YKL171W	3951.15	0	0	cytoplasm && nucleus	Non-essen Genes	161.51.21		cytoplasm	protein kinase	proteolysis and peptidolysis
YAR019C	3084.02	0	0	spindle pole && Ambiguous	Essentail Genes	161.41.71	CDC15	spindle pole body	protein kinase	cytokinesis	exit from mitosis	protein amino acid phosphorylation
YOL016C	20909.53	0	0	cytoplasm	Non-essen Genes	161.21.11	CMK2	cellular_component unknown	calcium/calmodulin-dependent protein kinase	protein amino acid phosphorylation	signal transduction
YHR082C	6096.61	0	0	cytoplasm	Non-essen Genes	161.41.91	KSP1	nucleus	protein serine/threonine kinase	protein amino acid phosphorylation
YNL280C	2539.14	0	0	ER	Non-essen Genes	-	ERG24	endoplasmic reticulum	C-14 sterol reductase	ergosterol biosynthesis
YGL180W	11032.91	0	0	punctate composite	Non-essen Genes	161.51.11	APG1	cytosol	protein serine/threonine kinase	protein serine/threonine kinase	autophagy
YDR425W	4150.03	0	0	endosome && cytoplasm && lipid particle	Non-essen Genes	-	SNX41	cellular_component unknown	molecular_function unknown	biological_process unknown
YNL227C	2880.19	1	0	cytoplasm	Non-essen Genes	201.21.21		cellular_component unknown	molecular_function unknown	endocytosis
YIL172C	2661.08	0	0	cytoplasm	Non-essen Genes	-		cellular_component unknown	glucosidase	biological_process unknown
YNL263C	17071.62	0	0	cytoplasm	Essentail Genes	-	YIF1	COPII-coated vesicle	molecular_function unknown	ER to Golgi transport
YMR120C	13525.44	0	0	cytoplasm	Non-essen Genes	-	ADE17	cytosol	IMP cyclohydrolase	phosphoribosylaminoimidazole-carboxamide formyltransferase	'de novo' IMP biosynthesis	'de novo' IMP biosynthesis
YDL179W	2708.28	0	0	cytoplasm	Non-essen Genes	51.31	PCL9	cyclin-dependent protein kinase holoenzyme complex	"cyclin-dependent protein kinase, regulator"	cell cycle
YIL002C	3304.72	0	0	cytoplasm	Non-essen Genes	-	INP51	membrane fraction	"inositol-1,4,5-trisphosphate 5-phosphatase"	cell wall organization and biogenesis	dephosphorylation	phosphatidylinositol biosynthesis
YPL203W	10904.41	1	0	nucleus	Non-essen Genes	161.11.11	TPK2	cAMP-dependent protein kinase complex	cytoplasm	cAMP-dependent protein kinase	protein serine/threonine kinase	RAS protein signal transduction	protein amino acid phosphorylation	pseudohyphal growth
YPL232W	4729.48	0	0	lipid particle	Non-essen Genes	-	SSO1	integral to plasma membrane	t-SNARE	Golgi to plasma membrane transport	non-selective vesicle fusion
YOR002W	4909.21	0	0	ER	Non-essen Genes	-	ALG6	endoplasmic reticulum	"transferase, transferring hexosyl groups"	oligosaccharide-PP-dolichol assembly	protein amino acid glycosylation