ORF name Slide_Ave_Signal(before GST) Pro_pro interaction Known substrate localization Essentiality MIPS annotation Common name SGD annotation YHL020C 8390.5 0 0 nuclear periphery Non-essen Genes - OPI1 nucleus transcription co-repressor negative regulation of transcription from Pol II promoter phospholipid biosynthesis YJR096W 9707.88 0 0 cytoplasm && nucleus Non-essen Genes - cytoplasm molecular_function unknown arabinose metabolism YOR362C 4781 0 0 cytoplasm && nucleus Essentail Genes - PRE10 20S core proteasome complex proteasome endopeptidase ubiquitin-dependent protein catabolism YBR178W 6119 0 0 cytoplasm && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YNL272C 7573.17 0 0 bud neck && cytoplasm && Ambiguous Essentail Genes - SEC2 cytoplasmic vesicle cytosol guanyl-nucleotide exchange factor exocytosis YMR241W 10441.25 0 0 mitochondrion Non-essen Genes - YHM2 mitochondrial inner membrane tricarboxylate carrier tricarboxylic acid transport YHL021C 8325.15 0 0 mitochondrion Non-essen Genes - molecular_function unknown biological_process unknown YKR048C 7382.69 0 0 cytoplasm Non-essen Genes - NAP1 nucleus protein binding M phase of mitotic cell cycle nucleosome assembly nucleosome assembly YGR223C 8933.2 0 0 cytoplasm Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YGL245W 14009.67 0 0 cytoplasm Essentail Genes - cellular_component unknown glutamate-tRNA ligase glutathione transferase biological_process unknown YJR105W 9740.26 0 0 cytoplasm && nucleus Non-essen Genes - ADO1 cellular_component unknown adenosine kinase adenosine kinase purine base metabolism YGR063C 10570.91 0 0 nucleus Non-essen Genes - SPT4 nucleus transcription elongation factor complex Pol II transcription elongation factor Pol II transcription elongation factor RNA elongation from Pol II promoter establishment and/or maintenance of chromatin architecture "regulation of transcription, DNA-dependent" "regulation of transcription, DNA-dependent" YJR141W 6962.76 0 0 nucleus Essentail Genes - molecular_function unknown biological_process unknown YPR160W 9093.53 0 0 cytoplasm Non-essen Genes - GPH1 cytoplasm glycogen phosphorylase glycogen catabolism YBL031W 6149.68 0 0 microtubule Non-essen Genes - SHE1 cellular_component unknown molecular_function unknown biological_process unknown YBL024W 10581.7 0 0 nucleus Non-essen Genes - NCL1 nucleus tRNA (cytosine-5-)-methyltransferase tRNA methylation YOR335C 5510 0 0 cytoplasm Essentail Genes - ALA1 cytoplasm alanine-tRNA ligase alanine-tRNA ligase alanyl-tRNA aminoacylation alanyl-tRNA aminoacylation YJR094W-A 9787.96 0 0 cytoplasm Non-essen Genes - YNL117W 7318.66 0 0 cytoplasm Non-essen Genes - MLS1 cytoplasm peroxisomal matrix malate synthase glyoxylate cycle YOR044W 5930.15 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YJR142W 8460.5 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YIL070C 10756.89 0 0 mitochondrion Non-essen Genes - MAM33 mitochondrial matrix molecular_function unknown aerobic respiration YNL186W 18922.48 0 0 cytoplasm && nucleus Non-essen Genes 191.51 UBP10 nucleus ubiquitin-specific protease protein deubiquitination YOR193W 5011.25 0 0 peroxisome Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YGR210C 8696.16 0 0 cytoplasm Non-essen Genes 61.99 molecular_function unknown biological_process unknown YDL070W 10432.62 0 0 cytoplasm && nucleus Non-essen Genes - BDF2 nucleus molecular_function unknown biological_process unknown YDL220C 5438 0 0 cytoplasm && nucleus Essentail Genes - CDC13 telomere single-stranded DNA binding telomere capping telomere maintenance YNL064C 8375.75 0 0 cytoplasm && nucleus Non-essen Genes 101.61 YDJ1 cytosol ATPase stimulator Hsp70/Hsc70 protein regulator chaperone regulator chaperone regulator protein-mitochondrial targeting YGR276C 15490.43 0 0 cytoplasm && nucleus Non-essen Genes - RNH70 nucleus 3'-5' exonuclease 3'-5' exonuclease ribonuclease H DNA replication RNA processing YGR078C 7461.88 0 0 cytoplasm Non-essen Genes - PAC10 cytoplasm tubulin binding tubulin folding tubulin folding YGR220C 5792.8 0 0 mitochondrion Non-essen Genes - MRPL9 mitochondrial large ribosomal subunit peptidyltransferase structural constituent of ribosome protein biosynthesis ribosomal large subunit assembly and maintenance YGR024C 9785.78 0 0 cytoplasm && nucleus Essentail Genes - cellular_component unknown molecular_function unknown biological_process unknown YML037C 8497.14 0 0 Golgi to vacuole Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YAL042W 6729.94 0 0 Golgi to vacuole Non-essen Genes - ERV46 COPII-coated vesicle "endoplasmic reticulum membrane, intrinsic protein" integral to Golgi membrane molecular_function unknown ER to Golgi transport YMR229C 6199.26 0 0 nucleolus Essentail Genes - RRP5 nucleolus nucleolus organizer complex RNA binding snoRNA binding processing of 20S pre-rRNA rRNA processing YHR185C 5522.78 0 0 nucleolus Non-essen Genes - PFS1 cellular_component unknown molecular_function unknown spore wall assembly (sensu Fungi) YHL027W 5713.49 0 0 cytoplasm Non-essen Genes 201.21.21 RIM101 nucleus specific transcriptional repressor meiosis negative regulation of transcription from Pol II promoter response to pH sporulation (sensu Saccharomyces) YJR089W 7477.26 0 0 spindle pole && microtubule && nucleus Non-essen Genes - BIR1 kinetochore kinetochore molecular_function unknown chromosome segregation YJR115W 5275.96 0 0 spindle pole && microtubule && nucleus Non-essen Genes - molecular_function unknown biological_process unknown YML035C 8820.92 0 0 cytoplasm Non-essen Genes - AMD1 cellular_component unknown AMP deaminase purine nucleotide metabolism YHR001W 6634.99 0 0 cytoplasm Non-essen Genes - OSH7 cellular_component unknown oxysterol binding steroid biosynthesis steroid biosynthesis YMR284W 6006.11 0 0 cytoplasm && nucleus Non-essen Genes - YKU70 chromatin nuclear membrane telomere telomeric heterochromatin damaged DNA binding chromatin assembly/disassembly double-strand break repair via homologous recombination double-strand break repair via nonhomologous end-joining telomere maintenance YPR072W 8631.59 0 0 cytoplasm Non-essen Genes - NOT5 CCR4-NOT core complex cytoplasm 3'-5' exoribonuclease poly(A) tail shortening regulation of transcription from Pol II promoter YER036C 7290.02 0 0 cytoplasm Essentail Genes 41.21 cellular_component unknown ATP-binding cassette (ABC) transporter biological_process unknown YIL021W 8842.98 0 0 nucleus Essentail Genes 141.21.11 RPB3 "DNA-directed RNA polymerase II, core complex" DNA-directed RNA polymerase II transcription from Pol II promoter YML042W 5101.61 0 0 nucleus Non-essen Genes - CAT2 mitochondrion peroxisomal matrix peroxisome carnitine O-acetyltransferase carnitine O-acetyltransferase carnitine metabolism YNL284C-A 7452.04 0 0 nucleus Non-essen Genes - MRPL10 mitochondrial large ribosomal subunit structural constituent of ribosome protein biosynthesis YHL003C 4396.19 0 0 ER Non-essen Genes - LAG1 endoplasmic reticulum protein transporter aging ceramide biosynthesis YOR210W 9376.97 0 0 nucleolus && nucleus Essentail Genes 141.21.11 RPB10 DNA-directed RNA polymerase I complex "DNA-directed RNA polymerase II, core complex" DNA-directed RNA polymerase III complex DNA-directed RNA polymerase I DNA-directed RNA polymerase II DNA-directed RNA polymerase III transcription from Pol I promoter transcription from Pol II promoter transcription from Pol III promoter YGL231C 4896.17 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YKL012W 5582.16 0 0 nucleus Essentail Genes - PRP40 commitment complex commitment complex snRNP U1 snRNP U1 snRNP U1 RNA binding mRNA splicing YIL004C 6502.04 0 0 Ambiguous Essentail Genes - BET1 COPII-coated vesicle endoplasmic reticulum membrane v-SNARE ER to Golgi transport ER to Golgi transport retrograde (Golgi to ER) transport YLL057C 6846.32 0 0 Ambiguous Non-essen Genes - cellular_component unknown sulfonate dioxygenase sulfur metabolism sulfur metabolism YIL051C 6583.74 0 0 mitochondrion Essentail Genes - MMF1 mitochondrial matrix mitochondrion molecular_function unknown isoleucine biosynthesis mitochondrial genome maintenance YGL246C 3683.1 0 0 nucleus Non-essen Genes - RAI1 nucleus enzyme regulator RNA catabolism processing of 27S pre-rRNA YLR303W 8246.73 0 0 nucleus Non-essen Genes - MET17 cytoplasm O-acetylhomoserine (thiol)-lyase methionine metabolism YMR239C 6227.86 0 0 nucleolus && nucleus Essentail Genes - RNT1 nucleolus ribonuclease III 35S primary transcript processing YFL063W 6015.12 0 0 nucleolus && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YDL153C 7062.79 0 0 nucleolus && nucleus Essentail Genes - SAS10 nucleus small nucleolar ribonucleoprotein complex snoRNA binding establishment and/or maintenance of chromatin architecture establishment and/or maintenance of chromatin architecture processing of 20S pre-rRNA processing of 20S pre-rRNA YMR115W 8290.26 0 0 mitochondrion Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YPR063C 5285.66 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YER098W 6654.09 0 0 cytoplasm Non-essen Genes 191.51 UBP9 cytoplasm ubiquitin-specific protease protein deubiquitination YMR155W 9622.59 0 0 cytoplasm Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YOL125W 4513.34 0 0 cytoplasm && nucleus Non-essen Genes - molecular_function unknown biological_process unknown YAL068C 7497.38 0 0 cytoplasm && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YJR095W 8461.57 0 0 cytoplasm && nucleus Non-essen Genes - SFC1 mitochondrial inner membrane succinate/fumarate antiporter fumarate transport succinate transport YNL212W 8125.82 0 0 cytoplasm Non-essen Genes - VID27 cellular_component unknown molecular_function unknown biological_process unknown YGR228W 7918.5 0 0 cytoplasm Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YDL230W 6663.37 0 0 cytoplasm Non-essen Genes 181.11.31 PTP1 cellular_component unknown protein tyrosine phosphatase protein tyrosine phosphatase protein amino acid dephosphorylation protein amino acid dephosphorylation YOR089C 6686.57 0 0 cytoplasm && nucleus Non-essen Genes 61.21.21 VPS21 late endosome GTPase RAB small monomeric GTPase RAB small monomeric GTPase endocytosis protein-vacuolar targeting YHR044C 6722.97 0 0 cytoplasm && nucleus Non-essen Genes - DOG1 cellular_component unknown 2-deoxyglucose-6-phosphatase glucose metabolism YLL008W 9050.06 0 0 nucleolus && cytoplasm && nucleus Essentail Genes - DRS1 nucleolus ATP dependent RNA helicase 35S primary transcript processing ribosomal large subunit assembly and maintenance YIL078W 6845.32 0 0 cytoplasm Essentail Genes - THS1 cytoplasm threonine-tRNA ligase protein biosynthesis