ORF name Slide_Ave_Signal(before GST) Pro_pro interaction Known substrate localization Essentiality MIPS annotation Common name SGD annotation YBL023C 3518.55 0 0 cytoplasm && nucleus Essentail Genes 41.41 MCM2 cytoplasm cytoplasm nucleus pre-replicative complex ATP dependent DNA helicase chromatin binding DNA replication initiation DNA unwinding pre-replicative complex formation and maintenance YML035C 3790.31 0 0 cytoplasm Non-essen Genes - AMD1 cellular_component unknown AMP deaminase purine nucleotide metabolism YJR043C 4598.77 0 0 cytoplasm && nucleus Non-essen Genes 141.11.21 POL32 delta DNA polymerase complex nucleus delta DNA polymerase base-excision repair lagging strand elongation leading strand elongation mismatch repair mutagenesis nucleotide-excision repair post-replication repair YGL245W 4008.14 0 0 cytoplasm Essentail Genes - cellular_component unknown glutamate-tRNA ligase glutathione transferase biological_process unknown YEL015W 3257.22 0 0 punctate composite Non-essen Genes - DCP3 cellular_component unknown molecular_function unknown biological_process unknown YFR022W 3148.56 0 0 punctate composite Non-essen Genes - molecular_function unknown biological_process unknown YMR053C 2594.05 0 0 punctate composite Non-essen Genes - STB2 Sin3 complex nucleus transcriptional repressor histone deacetylation YGL256W 2596.59 0 0 mitochondrion Non-essen Genes - ADH4 cellular_component unknown "alcohol dehydrogenase, zinc-dependent" fermentation YMR239C 3026.54 0 0 nucleolus && nucleus Essentail Genes - RNT1 nucleolus ribonuclease III 35S primary transcript processing YLR006C 5080.27 0 0 cytoplasm Non-essen Genes - SSK1 cytoplasm enzyme activator two-component response regulator osmosensory signaling pathway via two-component system osmosensory signaling pathway via two-component system response to hydrogen peroxide YNL201C 4304.14 0 0 nucleus Non-essen Genes - PSY2 cellular_component unknown molecular_function unknown biological_process unknown YCR073W-A 4250.67 0 0 nucleus Non-essen Genes - YOL125W 2869.75 0 0 cytoplasm && nucleus Non-essen Genes - molecular_function unknown biological_process unknown YMR184W 3098.54 0 0 cytoplasm Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YMR229C 3443.99 0 0 nucleolus Essentail Genes - RRP5 nucleolus nucleolus organizer complex RNA binding snoRNA binding processing of 20S pre-rRNA rRNA processing YAL028W 32893.69 0 0 nucleolus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YCR105W 3745.79 0 0 nucleolus Non-essen Genes - ADH7 soluble fraction alcohol dehydrogenase (NADP+) alcohol dehydrogenase (NADP+) alcohol metabolism YDL186W 3653.19 0 0 nucleolus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YDL002C 3803.93 0 0 nucleus Non-essen Genes - NHP10 cellular_component unknown molecular_function unknown biological_process unknown YML045W-A 3360.68 0 0 nucleus Non-essen Genes - molecular_function unknown biological_process unknown YDR259C 4195.06 0 0 nucleus Non-essen Genes 201.11.11.11 YAP6 nucleus RNA polymerase II transcription factor positive regulation of transcription from Pol II promoter YMR280C 12398.57 0 0 cytoplasm && nucleus Non-essen Genes 201.21.31 CAT8 nucleus specific RNA polymerase II transcription factor gluconeogenesis positive regulation of transcription from Pol II promoter YLR131C 4389.5 Non-essen Genes 201.21.21 cytoplasm && nucleus cytosol nucleus transcriptional activator G1-specific transcription in mitotic cell cycle YDR023W 4281.5 0 0 cytoplasm Essentail Genes - SES1 cytoplasm serine-tRNA ligase amino acid activation YBR225W 6615.67 0 0 Ambiguous Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YBL037W 4159.8 0 0 cell periphery && bud neck Non-essen Genes 31.11 APL3 AP-2 adaptor complex molecular_function unknown vesicle-mediated transport YPL080C 2533.25 0 0 cell periphery && bud neck Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YDL006W 7632.68 0 0 cell periphery && bud neck Non-essen Genes 181.11.21 PTC1 cytoplasm nucleus protein phosphatase type 2C mitochondrion inheritance protein amino acid dephosphorylation response to osmotic stress tRNA splicing YLL034C 4890 0 0 nucleolus && nucleus Essentail Genes 41.11 cellular_component unknown helicase biological_process unknown YDL166C 9204.88 0 0 cytoplasm && nucleus Essentail Genes - FAP7 nucleus molecular_function unknown response to oxidative stress YMR205C 3206.6 0 0 cytoplasm Non-essen Genes - PFK2 6-phosphofructokinase complex cytoplasm 6-phosphofructokinase glycolysis YDR379W 3229.82 0 0 cytoplasm Non-essen Genes - RGA2 intracellular Rho GTPase activator signal transducer actin filament organization apical bud growth establishment of cell polarity (sensu Saccharomyces) invasive growth isotropic bud growth pseudohyphal growth signal transduction during conjugation with cellular fusion small GTPase mediated signal transduction YLR258W 3048.75 0 0 punctate composite && cytoplasm && nucleus Non-essen Genes - GSY2 cytoplasm glycogen (starch) synthase glycogen (starch) synthase glycogen (starch) synthase glycogen metabolism glycogen metabolism glycogen metabolism YNL217W 3890.72 0 0 vacuole Non-essen Genes - molecular_function unknown biological_process unknown YPL077C 24199.01 0 0 vacuole Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YOR050C 3865.82 0 0 vacuole Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YKL168C 5501.3 0 0 cytoplasm Non-essen Genes 161.41.61 KKQ8 cellular_component unknown protein kinase biological_process unknown YMR165C 19171.49 0 0 cytoplasm Non-essen Genes - SMP2 cellular_component unknown molecular_function unknown aerobic respiration plasmid maintenance YBR273C 6026.7 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YOR207C 4970.09 0 0 nucleus Essentail Genes 141.21.11 RET1 DNA-directed RNA polymerase III complex DNA-directed RNA polymerase III transcription from Pol III promoter YDR002W 16383.85 0 0 nucleus Essentail Genes 81.31 YRB1 cytoplasm nucleus RAN protein binding G1/S transition of mitotic cell cycle RNA-nucleus export protein-nucleus import ubiquitin-dependent protein catabolism YDR518W 5938.25 0 0 nucleus Non-essen Genes - EUG1 endoplasmic reticulum protein disulfide isomerase protein disulfide isomerase protein disulfide-isomerase reaction protein folding YPR058W 4992.29 0 0 nucleus Non-essen Genes - YMC1 mitochondrial inner membrane transporter transport YNR006W 4166.81 0 0 endosome Non-essen Genes - VPS27 endosome protein binding protein-Golgi retention YKL146W 4692 0 0 ER Non-essen Genes 121 AVT3 vacuole neutral amino acid transporter neutral amino acid transporter neutral amino acid transporter neutral amino acid transport neutral amino acid transport YNL284C-A 3469.44 0 0 ER Non-essen Genes - MRPL10 mitochondrial large ribosomal subunit structural constituent of ribosome protein biosynthesis YGR038C-A 5604.96 0 0 ER Non-essen Genes - YCR100C 3360.46 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YNL272C 8279.6 0 0 bud neck && cytoplasm && Ambiguous Essentail Genes - SEC2 cytoplasmic vesicle cytosol guanyl-nucleotide exchange factor exocytosis YLR132C 4379.5 0 0 mitochondrion && cytoplasm && nucleus Essentail Genes - cellular_component unknown molecular_function unknown biological_process unknown YAL034C 6213.59 0 0 mitochondrion && cytoplasm && nucleus Non-essen Genes - FUN19 cellular_component unknown molecular_function unknown biological_process unknown YAR019C 10275.69 0 0 spindle pole && Ambiguous Essentail Genes 161.41.71 CDC15 spindle pole body protein kinase cytokinesis exit from mitosis protein amino acid phosphorylation YJL084C 13868.48 0 0 cytoplasm Non-essen Genes - cytoplasm cyclin binding biological_process unknown YDR293C 4638.21 0 0 cytoplasm Non-essen Genes - SSD1 cytoplasm RNA binding cell wall organization and biogenesis YJR141W 2945.5 0 0 cytoplasm Essentail Genes - molecular_function unknown biological_process unknown YMR238W 1515.75 0 0 ER Non-essen Genes - DFG5 "extrinsic to plasma membrane, GPI-anchored" molecular_function unknown cell wall biosynthesis (sensu Fungi) pseudohyphal growth YJL110C 3034.25 0 0 cytoplasm && nucleus Non-essen Genes 201.21.11 GZF3 nucleus specific RNA polymerase II transcription factor specific RNA polymerase II transcription factor negative regulation of transcription from Pol II promoter negative regulation of transcription from Pol II promoter nitrogen metabolism regulation of nitrogen utilization regulation of nitrogen utilization YLR030W 2639.5 0 0 cytoplasm && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YNL065W 7291.33 0 0 vacuole && cell periphery Non-essen Genes 121 AQR1 plasma membrane drug transporter monocarboxylic acid transporter drug transport monocarboxylic acid transport YDL156W 1525.75 0 0 cytoplasm && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YDR134C 20446.95 0 0 cytoplasm && nucleus Non-essen Genes - cell wall (sensu Fungi) molecular_function unknown biological_process unknown YOL091W 10024.33 0 0 cytoplasm && nucleus Non-essen Genes - SPO21 spindle pole body molecular_function unknown meiosis spore wall assembly (sensu Saccharomyces) YIL135C 9247.45 0 0 cytoplasm Non-essen Genes - VHS2 cellular_component unknown molecular_function unknown G1/S transition of mitotic cell cycle YDL149W 1974 0 0 cytoplasm Non-essen Genes - APG9 integral to membrane integral to membrane membrane fraction molecular_function unknown autophagic vacuole formation autophagy protein-vacuolar targeting YBL024W 7057.16 0 0 nucleus Non-essen Genes - NCL1 nucleus tRNA (cytosine-5-)-methyltransferase tRNA methylation YDR072C 3568.91 0 0 Ambiguous Non-essen Genes - IPT1 membrane fraction "transferase, transferring phosphorus-containing groups" mannosyl diphosphorylinositol ceramide metabolism YDL153C 4233.22 0 0 Ambiguous Essentail Genes - SAS10 nucleus small nucleolar ribonucleoprotein complex snoRNA binding establishment and/or maintenance of chromatin architecture establishment and/or maintenance of chromatin architecture processing of 20S pre-rRNA processing of 20S pre-rRNA YMR115W 5040.02 0 0 mitochondrion Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YGR220C 3140.56 0 0 mitochondrion Non-essen Genes - MRPL9 mitochondrial large ribosomal subunit peptidyltransferase structural constituent of ribosome protein biosynthesis ribosomal large subunit assembly and maintenance YOR335C 2576.58 0 0 cytoplasm Essentail Genes - ALA1 cytoplasm alanine-tRNA ligase alanine-tRNA ligase alanyl-tRNA aminoacylation alanyl-tRNA aminoacylation YER098W 5411.06 0 0 cytoplasm Non-essen Genes 191.51 UBP9 cytoplasm ubiquitin-specific protease protein deubiquitination YDR330W 2898.75 0 0 cytoplasm && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown ubiquitin-dependent protein catabolism YLR249W 3301 0 0 cytoplasm Essentail Genes 41.61 YEF3 ribosome translation elongation factor translational elongation YNR047W 5785.03 0 0 cytoplasm Non-essen Genes 161.11.41 cellular_component unknown protein kinase response to pheromone YML058W 4260.5 0 0 cytoplasm && nucleus Non-essen Genes - SML1 enzyme inhibitor molecular_function unknown mitochondrion organization and biogenesis response to DNA damage YML037C 7594.12 0 0 Golgi to vacuole Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YDL128W 5108.75 0 0 ER Non-essen Genes - VCX1 vacuolar membrane vacuole (sensu Fungi) calcium ion transporter calcium ion transporter calcium ion transporter calcium:hydrogen antiporter calcium ion homeostasis calcium ion transport calcium ion transport YPR013C 7707.72 0 0 Ambiguous Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YNL066W 6127.04 0 0 vacuole Non-essen Genes - SUN4 cell wall mitochondrial matrix glucosidase mitochondrion organization and biogenesis YFR009W 2973 0 0 cytoplasm Non-essen Genes 41.21 GCN20 cytosol cytosolic ribosome (sensu Eukarya) molecular_function unknown regulation of translational elongation regulation of translational elongation YBR086C 5026.1 0 0 cell periphery Non-essen Genes - IST2 cellular_component unknown molecular_function unknown response to osmotic stress YJL108C 3863.4 0 0 cell periphery Non-essen Genes - PRM10 integral to membrane molecular_function unknown conjugation with cellular fusion YNL074C 8501.9 0 0 cytoplasm Non-essen Genes - MLF3 cellular_component unknown molecular_function unknown response to drug YDL209C 2107.5 0 0 nucleus Essentail Genes - CWC2 spliceosome complex molecular_function unknown mRNA splicing mRNA splicing YBR108W 7199.68 0 0 nucleus Non-essen Genes - molecular_function unknown biological_process unknown YGL134W 7043.53 0 0 cytoplasm Non-essen Genes 51.31 PCL10 cyclin-dependent protein kinase holoenzyme complex "cyclin-dependent protein kinase, regulator" "cyclin-dependent protein kinase, regulator" regulation of glycogen biosynthesis regulation of glycogen biosynthesis regulation of glycogen catabolism YGR126W 2366.67 0 0 cytoplasm && nucleus Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YAL007C 2038.5 0 0 ER Non-essen Genes - ERP2 COPII-coated vesicle molecular_function unknown ER to Golgi transport YKL093W 12125.09 0 0 ER Non-essen Genes - MBR1 cellular_component unknown molecular_function unknown aerobic respiration YML080W 1864.75 0 0 nucleus Non-essen Genes - DUS1 cellular_component unknown tRNA dihydrouridine synthase tRNA modification YBR043C 4216.66 0 0 cell periphery Non-essen Genes 121 AQR2 cellular_component unknown molecular_function unknown biological_process unknown YDL230W 1462.25 0 0 cytoplasm Non-essen Genes 181.11.31 PTP1 cellular_component unknown protein tyrosine phosphatase protein tyrosine phosphatase protein amino acid dephosphorylation protein amino acid dephosphorylation YNL027W 8467.62 0 0 cytoplasm Non-essen Genes 201.21.21 CRZ1 cytoplasm nucleus DNA binding transcription factor transcription factor transcription factor calcium-mediated signaling calcium-mediated signaling calcium-mediated signaling "regulation of transcription, DNA-dependent" YDL070W 10968.47 0 0 cytoplasm && nucleus Non-essen Genes - BDF2 nucleus molecular_function unknown biological_process unknown YAL034W-A 5116.12 0 0 cytoplasm && nucleus Non-essen Genes - YBL011W 22130.78 0 0 ER Non-essen Genes - SCT1 cellular_component unknown glycerol-3-phosphate O-acyltransferase glycerol-3-phosphate O-acyltransferase glycerol-3-phosphate O-acyltransferase phospholipid biosynthesis phospholipid biosynthesis YDL198C 2451.75 0 0 ER Non-essen Genes - YHM1 mitochondrial inner membrane transporter mitochondrial genome maintenance transport YPL257W-A 3705.75 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YML012W 4491.66 0 0 ER Non-essen Genes - ERV25 COPII-coated vesicle molecular_function unknown ER to Golgi transport YFR014C 5052.9 0 0 cytoplasm - - CMK1 cytoplasm calmodulin-dependent protein kinase I protein amino acid phosphorylation signal transduction YER122C 4237.26 0 0 Golgi && Golgi to ER Non-essen Genes 201.21.99 GLO3 ER-Golgi intermediate compartment ARF GTPase activator ER to Golgi transport ER to Golgi transport retrograde (Golgi to ER) transport retrograde (Golgi to ER) transport retrograde (Golgi to ER) transport YPR050C 5825.75 0 0 Golgi && Golgi to ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YOR224C 7273.75 0 0 nucleus Essentail Genes 141.21.11 RPB8 DNA-directed RNA polymerase I complex "DNA-directed RNA polymerase II, core complex" DNA-directed RNA polymerase III complex DNA-directed RNA polymerase I DNA-directed RNA polymerase II DNA-directed RNA polymerase III transcription from Pol I promoter transcription from Pol II promoter transcription from Pol III promoter YOR028C 6894.78 0 0 cytoplasm && nucleus Non-essen Genes 201.11.11.11 CIN5 nucleus RNA polymerase II transcription factor regulation of transcription from Pol II promoter response to drug salinity response YNL078W 3697.46 0 0 cell periphery && bud neck Non-essen Genes - NIS1 bud neck nucleus molecular_function unknown regulation of mitosis YGL051W 3096.75 0 0 cell periphery && bud neck Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown YGR276C 4767.5 0 0 cell periphery && bud neck Non-essen Genes - RNH70 nucleus 3'-5' exonuclease 3'-5' exonuclease ribonuclease H DNA replication RNA processing YGL186C 4057.3 0 0 ER Non-essen Genes 121 molecular_function unknown biological_process unknown YNL187W 3009 0 0 ER Non-essen Genes - cellular_component unknown molecular_function unknown biological_process unknown