GS000_S13_S11a GS000_S13_S11b GS000_S03 GS000_S13 GS001a GS001b GS001c GS002 GS003 GS004 GS005 GS006 GS007 GS008 GS009 GS010 GS011 GS012 GS013 GS014 GS015 GS016 GS017 GS018 GS019 GS020 GS021 GS022 GS023 GS025 GS026 GS027 GS028 GS029 GS030 GS031 GS032 GS033 GS034 GS035 GS036 GS037 GS038 GS039 GS040 GS041 GS042 GS043 GS044 GS045 GS046 GS047 GS048 GS049 GS050 GS051 M00009(Citrate cycle) 6211 4899 4493 4531 479 433 1587 1459 691 669 559 916 596 1517 1004 1091 1693 1784 1309 1761 1700 1698 3113 1861 1817 3032 1608 1810 1753 344 1429 3118 2833 1980 6008 6819 1446 7224 1912 2177 1035 975 10 22 7 19 12 1 5 14 6 962 7 12 1 1590 M00632(Reductive carboxylate cycle) 5584 4078 4067 3816 442 364 1353 1188 598 565 457 772 520 1380 831 967 1451 1375 1125 1562 1510 1498 2771 1653 1556 2400 1454 1657 1559 300 1256 2626 2426 1698 4966 5833 1342 6166 1651 1901 951 889 5 19 6 17 11 2 4 16 6 828 5 6 4 1421 M00001(Glycolysis) 4591 3588 4080 3536 403 402 1104 1034 566 507 468 686 475 1246 859 864 1478 1591 1051 1358 1572 1458 2887 1734 1646 2901 1420 1491 1463 567 1199 2438 2084 1643 4653 5373 1450 7743 1649 1748 883 789 10 7 9 7 2 9 12 8 15 717 5 5 5 1317 M00112(Leucine biosynthesis, pyruvate => leucine) 4764 3584 3179 3624 283 364 1143 1052 530 532 472 699 600 1318 875 883 1302 1269 978 1482 1307 1220 2424 1497 1493 2484 1342 1377 1223 329 1149 2355 2000 1507 4442 5163 1083 5391 1457 1446 774 671 10 15 8 4 11 18 8 12 4 732 4 10 7 1186 M00011(Citrate cycle, module 2) 4474 3710 3306 3329 360 326 1170 1062 506 513 413 694 452 1131 747 788 1219 1297 920 1284 1235 1220 2239 1335 1274 2206 1172 1315 1315 203 1042 2270 2102 1433 4524 5132 1051 5262 1386 1614 752 741 8 17 5 10 10 0 3 10 4 698 6 7 0 1192 M00201(Inosine monophosphate biosynthesis, PRPP + glutamine => IMP) 3873 3233 3562 3311 374 381 1120 1122 483 545 485 602 438 1103 812 660 1163 1139 856 1323 1358 1284 2485 1413 1574 1411 1150 1318 1330 498 1162 2074 1920 1418 4309 4960 1150 5913 1357 1643 727 682 8 5 7 5 3 7 12 10 3 741 2 11 12 1098 M00143(Isoleucine degradation, isoleucine => propionyl-CoA) 5572 3021 3899 2997 317 334 968 974 568 493 448 560 472 1533 729 796 842 747 1181 1312 1184 1269 2236 1270 1202 1881 1187 1183 1067 308 783 2040 1719 1225 3797 4806 816 4842 1119 1407 683 730 5 9 12 0 2 4 6 5 4 623 5 9 2 976 M00603(Complex I (NADH dehydrogenase), NADH dehydrogenase I) 3198 2744 2963 2931 121 200 915 844 343 361 267 610 354 1179 703 816 1475 1411 732 1264 1134 1135 2043 1197 1078 3188 1056 1247 1120 89 959 1692 1742 1381 3266 4913 823 2831 991 1117 684 514 11 5 5 12 10 2 10 1 2 566 12 3 6 1321 M00416(beta-Oxidation) 5478 2632 3193 2611 247 281 839 817 486 481 382 479 424 1424 627 690 672 610 1005 1132 971 1038 1858 1067 1047 1401 1022 1002 925 203 665 1723 1526 1061 3210 4106 629 3206 972 1200 563 646 6 13 7 2 0 4 4 4 8 538 2 7 1 874 M00107(Lysine biosynthesis, aspartate => lysine) 3414 2439 2190 2619 214 251 810 816 377 396 341 434 306 786 609 591 913 1005 694 1018 948 973 1781 1145 1059 1493 872 1030 922 236 859 1711 1586 1138 3448 4028 805 4269 1068 1162 559 516 5 10 4 7 5 8 4 8 2 452 13 7 6 966 M00204(Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP) 2630 2515 2475 2366 218 232 789 774 339 321 313 455 245 683 597 549 1031 1079 595 874 1012 901 1731 1115 1097 1811 889 1034 919 310 787 1509 1380 1078 3129 3672 862 4212 1005 1161 586 550 7 5 9 3 6 6 10 8 3 520 6 8 7 828 M00402(Fatty acid biosynthesis, elongation) 5375 2145 2698 2150 272 280 721 673 381 443 278 373 350 986 565 466 725 673 701 925 819 883 1550 977 933 1291 942 856 778 223 591 1470 1318 894 2941 3258 623 4012 919 1073 475 492 6 13 3 1 2 4 3 5 2 449 2 6 9 675 M00003(Gluconeogenesis) 2516 2160 2481 2135 225 253 704 623 378 322 331 498 300 737 578 540 837 926 609 886 982 937 1775 1038 1025 1774 852 897 888 380 742 1480 1280 1054 2981 3365 983 4290 1026 1159 547 503 3 7 8 1 2 4 13 3 9 486 3 1 5 796 M00134(Lysine degradation, lysine => saccharopine => acetoacetyl-CoA) 4316 2394 2409 2220 185 246 707 683 366 388 315 401 320 932 524 506 652 625 730 894 751 807 1537 871 920 1277 776 763 769 181 622 1518 1328 894 2932 3384 636 3212 834 1045 495 524 4 8 0 2 1 4 2 5 4 462 7 9 1 707 M00623(ATP synthase) 2309 2366 2473 2258 253 237 736 692 342 390 259 485 353 730 507 595 785 805 557 788 857 858 1512 985 964 1384 811 947 860 266 706 1537 1297 921 3118 3444 726 3050 876 998 436 446 6 10 8 1 11 1 6 0 2 456 7 2 0 704 M00616(F-type ATPase (Bacteria)) 2309 2366 2473 2258 253 237 736 692 342 390 259 485 353 730 507 595 785 805 557 788 857 858 1512 985 964 1384 811 947 860 266 706 1537 1297 921 3118 3444 726 3050 876 998 436 446 6 10 8 1 11 1 6 0 2 456 7 2 0 704 M00507(Heme biosynthesis, glutamate => protoheme/siroheme) 3350 2055 2050 2142 241 267 617 657 314 338 322 360 250 791 477 430 778 824 567 673 904 787 1482 945 949 1358 672 824 786 313 771 1584 1374 844 3055 3253 812 3454 986 1100 537 550 6 9 5 0 2 6 2 11 4 490 2 4 0 651 M00133(Lysine degradation, lysine => 6-amino-2-oxohexanoate => acetoacetyl-CoA) 4231 2351 2363 2180 175 236 687 664 360 375 294 394 313 899 507 487 640 614 712 880 730 799 1504 853 898 1267 749 742 759 177 605 1463 1267 861 2804 3299 612 3173 808 992 479 499 4 8 0 1 1 4 2 5 4 449 5 9 1 691 M00113(Isoleucine biosynthesis, pyruvate => isoleucine) 3251 2095 2088 2103 193 259 658 668 340 338 283 371 370 893 528 518 791 738 642 876 806 776 1554 930 883 1509 785 784 727 226 711 1518 1140 865 2665 3101 643 3688 872 855 469 407 4 8 4 0 8 6 6 7 0 490 4 6 0 647 M00121(Histidine biosynthesis, PRPP => histidine) 2614 2007 1916 2175 192 261 694 774 290 328 223 449 231 628 494 541 794 859 537 740 820 723 1395 902 878 1298 747 859 767 243 718 1391 1235 932 2755 3268 772 3851 844 945 429 491 0 5 11 3 5 8 9 3 9 406 8 1 7 717 M00470(Bile acid biosynthesis, cholesterol => cholate/deoxycholate) 3026 1872 2545 1749 202 240 646 657 327 283 269 325 321 992 537 481 678 630 711 829 729 757 1327 747 797 1723 834 662 620 213 503 1173 976 755 2272 2882 683 3280 684 860 441 368 2 2 7 2 3 3 1 6 2 380 2 4 1 602 M00002(Glycolysis, core module) 2029 1679 2019 1735 196 213 557 524 306 229 250 350 240 590 428 444 702 823 505 728 824 729 1449 857 870 1549 707 744 716 277 567 1201 1028 834 2339 2595 838 3582 865 899 437 415 3 3 8 3 2 5 7 3 9 390 1 1 5 648 M00111(Valine biosynthesis, pyruvate => valine) 2821 1848 1757 1862 161 217 607 598 298 282 250 348 344 782 466 470 743 682 563 800 714 688 1366 817 770 1401 702 724 647 187 634 1321 1011 773 2314 2783 576 3049 741 735 417 355 4 8 4 0 8 6 3 7 0 439 4 6 0 596 M00117(Chorismate biosynthesis, phosphoenolpyruvate + erythrose-4P => chorismate) 2364 1866 1874 1840 171 213 546 622 273 303 207 369 188 538 468 394 694 742 496 653 683 695 1337 850 820 1229 683 758 625 209 631 1183 1031 830 2530 2796 645 3238 772 842 383 366 7 2 4 2 3 9 0 5 6 353 4 8 0 629 M00434(C5 isoprenoid biosynthesis, non-mevalonate pathway) 2013 1741 1909 1798 182 216 562 600 256 239 222 313 218 696 402 403 653 753 465 677 747 655 1366 736 858 1497 688 754 673 248 673 1175 997 761 2291 2779 555 3622 757 759 325 421 2 3 2 2 1 2 4 2 6 335 2 3 0 566 M00145(Glycine biosynthesis, betaine => glycine) 2297 2138 1627 2337 63 169 564 770 345 312 271 393 294 729 412 538 403 318 598 853 709 588 1011 685 669 301 741 685 590 40 481 1264 1132 873 2828 4206 561 1553 818 898 411 512 4 12 9 5 2 2 1 5 3 453 0 1 2 682 M00012(Glyoxylate cycle) 2618 1942 1845 1931 167 164 644 642 279 283 190 367 253 596 430 463 623 589 569 780 678 683 1350 785 713 950 668 713 658 152 607 1319 1109 778 2447 2752 588 2337 730 785 397 393 2 7 7 7 3 0 0 7 4 373 3 4 3 640 M00401(Fatty acid biosynthesis, initiation) 2197 1648 1973 1674 205 206 623 492 301 299 246 308 272 611 420 424 539 486 489 688 790 657 1222 810 772 753 709 737 661 231 597 1178 1079 729 2588 2589 595 3173 770 849 408 413 6 4 3 2 4 3 1 1 5 412 3 5 8 519 M00142(Leucine degradation, leucine => acetoacetate + acetyl-CoA) 3739 1541 2099 1586 211 185 533 558 311 259 266 289 243 839 400 431 461 430 697 702 650 705 1182 676 615 1067 628 639 605 195 422 1145 927 698 2077 2473 477 3196 651 784 390 406 0 2 7 0 2 0 5 3 0 326 3 5 1 534 M00471(Bile acid biosynthesis, cholesterol => chenodeoxycholate/lithocholate) 3223 1731 1912 1641 127 171 523 665 369 350 283 387 343 730 467 416 595 498 547 748 536 563 1031 666 587 1030 674 586 518 154 461 1150 1054 766 2392 2879 544 2418 750 843 353 416 1 4 8 0 1 8 2 3 2 401 3 1 1 581 M00118(Tryptophan biosynthesis, chorismate => tryptophan) 2254 1710 1680 1926 165 173 564 601 279 315 247 310 219 542 406 394 624 626 530 658 749 577 1235 822 794 1191 616 672 607 210 617 1195 938 690 2479 2667 548 2798 652 761 359 318 2 1 9 3 0 9 2 8 8 338 2 4 0 586 M00005(Pentose phosphate pathway and PRPP biosynthesis) 2129 1476 1468 1513 158 145 501 525 241 283 236 262 210 590 366 388 633 643 392 712 659 613 1210 650 723 1320 658 589 581 318 510 1064 936 783 2128 2259 762 2988 792 754 420 329 2 11 3 9 2 2 5 2 3 334 0 0 2 840 M00630(C4-dicarboxylic acid cycle, NAD+ -malic enzyme type) 2839 1530 1602 1600 146 184 484 463 221 209 187 312 246 567 380 353 592 559 436 683 647 574 1188 704 698 1157 651 678 616 148 534 1108 1003 732 2012 2352 572 2527 684 809 381 367 4 5 5 2 1 2 4 10 2 334 3 4 5 686 M00015(Malonate semialdehyde pathway) 3059 1682 2012 1628 166 186 554 537 315 318 247 301 269 913 363 407 360 368 660 737 629 660 1217 678 681 858 627 629 608 147 422 1103 915 657 1986 2432 344 1952 578 741 360 398 0 9 2 2 0 4 4 0 4 326 2 4 0 522 M00108(Methionine biosynthesis, apartate => homoserine => methionine) 2724 1487 1546 1444 164 178 402 450 216 225 217 312 184 570 345 394 719 851 469 591 634 508 1096 660 711 1393 585 578 550 190 517 962 846 623 1860 2219 506 3618 638 690 304 300 1 6 3 5 8 5 5 0 4 314 4 5 2 529 M00318(Lipopolysaccharide biosynthesis, KDO2-lipid A) 2023 1606 1952 1715 231 205 541 556 262 211 237 291 195 387 369 307 370 431 390 613 640 590 1138 671 675 529 573 660 628 194 570 1172 982 819 2606 2517 532 1718 687 809 398 431 0 2 2 0 3 4 0 8 6 300 1 7 1 523 M00309(dTDP-Glucose, dTDP-galactose and dTDP-rhamnose biosynthesis) 2288 1041 1407 1279 184 129 436 578 250 159 203 263 181 452 327 249 662 676 376 552 618 624 1163 660 677 1753 524 678 619 293 479 898 871 712 1720 2239 668 3079 588 694 383 391 4 5 1 8 7 12 7 1 4 286 2 0 0 558 M00109(Threonine biosynthesis, apartate => homoserine => threonine) 1799 1484 1306 1498 131 157 432 498 205 193 197 289 143 444 326 392 602 641 393 568 604 522 1032 616 637 1043 509 587 555 144 515 935 884 656 1943 2331 482 2467 605 665 317 284 1 6 0 8 2 7 3 2 0 283 3 6 4 563 M00203(Guanine nucleotide biosynthesis, IMP => GDP/dGDP,GTP/dGTP) 1526 1212 1456 1191 144 146 359 563 231 250 289 201 211 433 339 259 611 609 470 472 544 513 925 579 623 1362 518 525 521 260 419 833 777 547 1687 1733 531 3048 603 645 269 271 3 1 3 7 3 3 5 10 2 226 2 5 2 437 M00004(Pentose phosphate pathway) 1885 1213 1166 1255 130 118 411 413 192 233 205 226 166 456 293 307 526 506 312 575 539 514 997 546 611 1067 554 489 506 282 421 879 772 655 1765 1796 632 2513 678 613 365 256 2 8 1 7 1 2 4 1 3 282 0 0 2 744 M00626(Reduced pentose phosphate cycle, Glyceraldehyde-3P => RuBP) 1701 1306 1377 1308 129 129 432 376 190 229 181 254 160 427 310 266 536 494 298 516 553 534 978 588 573 993 476 464 530 235 420 888 801 676 1799 2108 581 2534 507 651 293 272 1 7 2 0 0 4 10 3 3 277 2 0 1 447 M00202(Adenine nucleotide biosynthesis, IMP => ADP/dADP,ATP/dATP) 1529 1138 1330 1198 132 152 475 512 203 207 268 205 223 484 290 307 547 572 408 484 599 525 978 599 633 1153 492 527 525 248 471 888 796 606 1632 1863 507 2527 518 585 248 284 0 3 2 0 1 2 2 5 2 249 3 4 3 474 M00531(C1-unit interconversion) 1510 1509 1511 1452 108 122 437 443 209 235 181 289 182 516 293 335 532 482 343 499 557 526 955 544 538 1045 474 492 478 142 405 834 836 570 1660 2190 552 2061 533 590 276 344 2 4 1 3 0 3 2 10 2 276 3 0 2 427 M00512(Folate biosynthesis, GTP => THF) 1648 1125 1169 1130 130 127 409 394 190 141 177 214 167 432 255 309 449 594 307 505 508 464 898 511 493 953 427 503 461 147 424 816 677 482 1543 1889 494 2511 470 515 283 228 0 1 5 0 1 0 1 5 0 218 2 1 0 413 M00103(Glutamate biosynthesis, oxoglutarete => glutamate (glutamate synthase)) 1539 1467 1097 1356 113 102 404 511 160 222 143 295 205 448 305 362 418 436 376 581 395 455 734 453 468 659 524 515 414 40 363 782 786 660 1745 1970 418 1644 501 575 299 275 3 4 4 0 6 2 0 0 4 305 2 3 0 414 M00511(Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD) 1484 1114 1091 1156 133 121 366 386 171 202 166 258 102 337 286 260 447 481 359 423 507 481 845 518 595 860 438 465 440 171 424 774 691 545 1684 1839 397 2383 503 551 286 278 3 0 0 0 3 5 1 0 6 236 0 3 0 419 M00510(Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P) 1476 1166 1187 1162 165 144 377 413 204 214 186 233 169 402 240 217 392 416 374 449 469 399 811 431 536 770 423 473 420 134 380 797 705 538 1762 1968 423 2336 539 575 224 276 0 2 1 2 0 3 2 4 1 239 1 2 1 372 M00010(Citrate cycle, module 1) 1737 1189 1187 1202 119 107 417 397 185 156 146 222 144 386 257 303 474 487 389 477 465 478 874 526 543 826 436 495 438 141 387 848 731 547 1484 1687 395 1962 526 563 283 234 2 5 2 9 2 1 2 4 2 264 1 5 1 398 M00503(Ubiquinone biosynthesis, chorismate => ubiquinone, prokaryotes) 1776 1311 1302 1305 129 111 365 446 201 157 176 249 164 373 277 292 424 338 312 431 491 456 783 464 462 580 415 501 381 110 364 807 734 554 1524 1887 455 1812 539 610 243 268 1 6 0 1 5 3 0 1 1 240 1 1 5 383 M00206(Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP) 1185 916 1215 999 112 133 328 510 203 218 281 204 228 428 266 288 499 540 416 441 430 464 781 435 507 1237 431 418 382 215 374 731 710 526 1405 1591 483 2421 433 520 225 230 2 2 3 4 0 4 1 7 2 211 2 0 5 378 M00614(Complex IV (Cytochrome c oxidase), cytochrome o ubiquinol oxidase/cytochrome c oxidase/quinol oxidase polypeptide) 2051 1134 1094 1194 83 84 389 343 116 126 120 252 178 337 256 260 422 474 252 520 443 459 800 557 459 879 458 406 455 137 385 757 642 550 1492 1611 272 1645 537 475 295 280 2 3 3 3 4 3 0 4 0 278 9 5 0 450 M00125(Ornithine biosynthesis, glutamate => ornithine) 1718 974 931 1117 111 152 318 404 130 193 188 233 142 398 247 288 495 428 296 436 412 364 773 482 463 769 415 381 394 120 403 680 661 436 1449 1597 443 2430 458 422 206 218 1 3 6 2 1 3 2 1 0 227 2 0 1 333 M00007(Pentose phosphate pathway, non-oxidative phase) 1289 1076 1073 1100 107 88 343 329 167 192 155 177 136 374 217 242 428 412 230 390 446 428 807 429 472 875 417 377 417 192 336 702 655 516 1515 1596 463 1843 432 522 232 221 1 6 1 7 1 2 4 0 3 230 0 0 2 449 M00629(C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type) 2220 892 1011 865 96 123 287 273 141 139 131 190 145 339 239 161 330 279 249 393 398 350 723 407 463 821 401 400 421 150 334 661 560 420 1149 1308 343 1957 434 548 254 207 2 0 4 1 0 0 1 3 0 213 0 4 4 420 M00505(Pantothenate biosynthesis, valine => pantothenate) 1461 819 901 948 110 112 334 322 160 127 158 198 128 338 237 236 418 390 298 381 456 394 753 441 404 954 406 421 398 121 339 657 534 377 1294 1438 373 1819 424 487 232 236 0 2 4 0 4 2 0 4 4 218 2 2 1 376 M00633(Methane oxidation, methylotroph, methane => CO2) 3230 1037 1098 952 51 79 223 397 132 162 110 160 176 413 197 241 350 367 302 428 305 334 523 352 310 493 333 279 241 54 229 515 513 284 1043 1666 332 1718 291 335 191 172 2 0 3 0 0 4 1 0 2 142 0 4 2 278 M00608(Complex II (succinate dehydrogenase / fumarate reductase), succinate dehydrogenase) 1020 1112 964 956 101 89 330 301 164 135 103 215 139 299 209 281 334 374 259 361 418 353 667 411 403 610 383 454 487 50 347 663 709 454 1334 1487 264 1620 467 519 275 248 4 10 4 5 0 0 2 0 0 213 1 2 0 403 M00302(UDP-N-Acetylglucosamine biosynthesis, fructose-6P => UDP-GlcNAc) 1338 1101 966 1021 78 92 349 313 160 164 108 181 117 284 203 242 421 415 272 397 431 341 679 431 437 700 374 382 339 74 373 674 654 449 1186 1591 396 1456 377 418 218 216 0 3 2 1 4 4 3 2 3 198 1 2 5 326 M00303(GDP-Mannose biosynthesis, fructose-6P => GDP-Man) 1219 880 1027 846 111 78 295 277 146 121 127 144 62 275 221 172 406 478 208 350 386 391 660 419 424 974 347 357 364 148 331 548 470 396 1081 1325 364 2310 357 358 203 214 5 0 2 0 6 0 0 1 1 190 2 3 1 276 M00126(Urea cycle) 1213 905 823 1011 84 100 265 332 129 144 130 178 95 281 220 191 401 385 229 303 379 367 603 399 415 696 411 377 344 88 307 643 559 459 1200 1550 313 1630 328 406 226 192 0 0 0 0 1 2 3 0 3 210 4 3 4 287 M00446(Glyceroglycolipid biosynthesis) 1411 756 871 782 97 90 271 240 137 108 85 145 70 179 174 125 437 420 228 333 403 366 661 420 351 1010 301 364 333 140 288 473 455 373 898 1142 575 2064 370 349 196 167 0 4 1 2 0 2 2 3 4 166 3 1 0 380 M00140(S-Adenosylmethionine biosynthesis, methionine => S-adenosylmethionine => methionine) 973 991 986 975 80 92 254 335 149 168 130 185 120 302 217 207 310 346 292 377 364 344 592 387 325 631 363 323 299 116 288 627 529 402 1154 1478 346 1451 313 427 203 205 0 1 0 4 2 0 2 0 2 183 0 0 3 309 M00501(NAD biosynthesis, aspartate => NAD) 1284 770 689 810 93 73 244 328 131 87 124 161 116 272 216 196 331 416 244 338 407 376 647 372 421 869 324 312 378 152 307 572 441 351 1014 1186 317 2049 349 380 177 197 4 6 5 2 1 8 1 0 4 158 0 3 0 272 M00631(C4-dicarboxylic acid cycle, NADP+ -malic enzyme type) 1264 884 687 899 64 64 275 271 130 122 104 160 121 255 195 238 327 298 241 378 363 328 620 398 383 536 378 343 321 58 310 597 583 389 1207 1417 294 1182 429 423 217 211 2 6 0 0 0 2 5 9 0 203 3 0 5 358 M00636(Sulfur reduction, sulfate => H2S) 1274 744 694 749 105 117 222 262 154 135 128 146 145 495 196 217 328 357 243 328 325 266 520 329 316 623 304 301 303 88 291 586 493 363 881 1234 374 1848 414 370 208 198 1 6 2 0 8 4 0 0 0 220 4 1 0 310 M00523(Ptrescine metabolism, N-acetylation, putrescine => 4-aminobutanoate) 1679 809 857 748 64 93 238 325 195 164 152 189 192 309 180 179 305 251 258 339 262 238 489 322 284 431 323 289 269 80 230 578 523 362 1241 1389 269 1207 382 465 165 206 0 4 3 0 1 6 0 3 0 219 4 0 0 263 M00139(Methionine degradation) 891 887 921 861 103 90 256 307 147 163 134 176 106 281 207 184 294 343 272 356 344 353 588 371 318 649 319 329 281 114 281 600 503 379 1109 1266 313 1290 297 438 194 188 0 0 0 4 2 4 2 0 2 167 0 0 3 291 M00150(Tryptophan metabolism, tryptophan => serotonin => 5-hydroxyindoleacetate/melatonin) 1769 772 844 740 67 91 232 324 191 160 153 182 190 309 176 179 294 244 253 346 266 238 478 315 277 434 328 285 273 77 231 574 524 362 1248 1403 260 1163 381 462 162 200 0 4 3 0 1 6 0 3 0 220 3 0 0 266 M00301(UDP-glucose and UDP-galactose biosynthesis) 1168 678 771 784 64 65 212 272 82 86 73 116 65 207 153 119 354 394 199 307 316 321 609 362 347 1155 278 343 330 140 251 465 455 379 900 1134 307 1192 273 349 191 188 0 2 0 6 0 6 2 1 0 169 1 0 1 305 M00114(Serine biosynthesis, glycerate-3P => serine) 1097 635 840 695 83 89 228 208 109 99 124 120 113 327 153 159 377 479 274 319 279 290 484 267 333 759 291 289 251 80 199 476 454 309 870 1067 302 1736 304 373 159 163 0 1 0 3 0 0 1 2 1 153 1 0 0 220 M00516(Ascorbate biosynthesis, animals) 1233 728 801 794 67 83 257 252 108 104 84 145 63 213 183 133 271 313 186 297 331 268 563 349 388 658 293 309 300 139 244 498 389 325 985 974 289 1186 373 319 151 164 0 5 5 0 4 3 0 4 4 132 0 1 5 278 M00102(Glutamine biosynthesis, glutamate => glutamine) 1081 811 794 826 47 75 221 297 158 143 95 186 159 241 180 187 231 258 194 366 279 214 432 295 314 559 314 262 261 63 184 492 410 377 1044 1465 206 1044 318 328 176 149 0 1 2 2 0 3 2 5 2 178 2 2 0 228 M00415(beta-Oxidation, acyl-CoA synthesis) 1602 619 853 646 117 125 200 224 102 101 105 123 116 354 176 215 197 232 245 327 269 274 506 313 330 493 287 272 265 101 247 428 372 264 761 1071 249 1354 280 302 160 116 0 3 1 4 1 4 6 2 0 145 3 3 0 229 M00137(Methionine biosynthesis, intermediates, homoserine => O-acetylhomoserine => L-homocysteine) 1045 722 645 763 89 98 250 259 115 130 88 167 128 309 162 191 247 238 211 296 273 336 486 328 321 400 272 302 257 74 220 492 408 349 907 1193 217 1258 364 345 177 173 0 0 1 4 2 1 1 1 0 187 2 1 0 271 M00205(Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP) 733 643 805 744 89 57 222 250 116 93 104 117 83 216 143 166 329 312 192 257 303 294 520 310 308 559 277 312 291 83 254 464 407 328 951 1134 307 1248 297 352 175 145 1 0 2 1 0 2 0 2 0 166 3 0 3 251 M00147(Cysteine metabolism, cysteine => 3-mercaptopyruvate => pyruvate) 1692 525 702 574 64 96 155 164 91 84 89 111 108 245 149 100 249 242 186 253 242 217 429 234 284 600 257 262 255 91 198 429 363 292 697 818 252 1433 228 325 148 125 2 0 4 1 0 0 1 1 2 129 0 4 0 276 M00514(Phylloquinone biosynthesis, chorismate => phylloquinone) 1556 373 446 513 123 95 150 156 95 72 79 100 69 172 137 105 381 427 197 147 224 203 505 253 286 1002 194 233 185 153 227 364 291 229 578 689 164 2257 314 272 102 107 0 2 1 0 1 0 0 2 0 81 0 3 1 160 M00104(Proline biosynthesis, glutamate => proline) 938 736 577 731 52 69 244 199 79 85 96 152 68 207 156 159 260 261 196 237 298 266 520 291 301 442 214 295 317 64 250 470 370 282 877 960 201 1389 255 271 135 115 0 3 0 5 0 0 4 0 0 158 1 3 0 214 M00627(CAM, dark) 987 659 606 692 81 65 241 238 96 109 67 156 101 230 161 154 249 185 183 301 280 250 545 317 286 411 264 285 261 57 220 492 413 309 910 1046 209 933 316 367 156 153 0 1 1 1 1 0 0 6 2 138 0 0 4 274 M00135(Ectoine biosynthesis) 1037 713 595 671 69 60 208 207 96 89 86 103 76 208 162 158 262 289 169 269 231 214 474 279 283 479 214 248 252 74 219 436 430 273 891 1068 252 1378 262 321 159 121 1 3 0 3 1 4 1 0 0 114 0 2 2 248 M00502(Menaquinone biosynthesis, chorismate => menaquinone) 1556 373 446 512 106 95 146 148 88 66 76 97 67 172 133 100 373 423 193 144 223 202 504 253 286 987 191 231 183 151 227 361 283 229 572 677 164 2243 310 261 100 103 0 2 1 0 1 0 0 2 0 80 0 3 1 160 M00160(Dopamine / noradrenaline / adrenaline metabolism) 1054 723 749 691 40 64 213 254 124 142 91 152 107 262 211 181 210 174 202 311 186 236 396 260 239 327 242 227 199 58 183 457 426 333 944 1149 209 874 290 309 148 172 0 0 0 0 0 2 2 0 2 133 0 1 1 208 M00146(Cysteine metabolism, cysteine => 3-sulfino-L-alanine => pyruvate) 1605 497 668 540 57 91 145 156 83 70 86 107 104 223 143 88 228 229 166 239 235 200 408 227 268 572 246 250 247 86 192 400 343 270 663 764 237 1240 217 308 145 117 2 0 4 1 0 0 1 1 0 119 0 4 0 262 M00628(CAM, light) 786 679 533 681 36 48 190 192 97 85 83 124 97 186 138 195 220 253 192 270 247 235 412 264 241 297 269 251 197 21 209 414 446 283 909 1074 211 700 269 269 147 160 2 6 0 0 0 2 5 7 0 144 3 0 1 245 M00138(Methionine salvage pathway) 1042 583 487 549 52 64 157 216 88 84 77 136 87 183 119 136 147 145 151 205 225 223 411 301 241 356 220 222 231 113 267 409 348 234 661 819 204 1075 209 234 124 110 0 0 1 2 2 0 0 0 0 127 1 0 4 260 M00120(Tyrosine biosynthesis, chorismate => tyrosine) 809 575 462 615 43 60 182 220 89 87 80 136 53 178 152 135 192 207 166 206 214 174 394 228 209 356 220 202 225 87 214 373 322 260 797 849 200 1109 230 262 95 142 2 0 3 0 0 2 7 0 0 108 3 0 1 194 M00307(UDP-N-Acetylmuramate biosynthesis, UDP-GlcNAc => UDP-MurNAc) 642 486 537 548 44 60 167 161 80 79 59 103 51 163 112 119 273 284 140 184 258 215 394 214 231 454 188 221 227 52 210 368 315 240 789 811 199 1016 204 271 121 98 2 1 6 2 0 2 1 0 1 90 0 0 4 168 M00513(Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P) 988 537 465 553 67 74 182 144 77 71 81 117 37 145 115 132 207 167 115 201 229 185 392 228 278 253 175 220 211 93 208 350 329 208 768 717 203 877 249 242 95 101 0 2 3 0 6 0 1 0 1 119 0 1 1 155 M00414(Fatty acid biosynthesis, elongation, mitochondria) 865 616 672 586 40 59 171 187 93 68 74 108 65 186 125 140 118 61 166 229 190 204 389 228 231 183 197 230 198 36 155 350 315 212 724 986 158 449 208 243 133 136 0 2 0 0 0 2 0 3 4 117 0 1 0 187 M00308(CMP-N-Acetylneuraminate biosynthesis (mammals), ManNAc => Neu5Ac-9P => CMP-Neu5Ac) 466 463 604 582 36 61 171 153 64 54 45 98 48 124 118 92 171 169 159 204 262 184 397 254 247 315 216 254 200 42 186 352 307 293 751 1010 220 773 191 240 128 87 7 1 0 1 0 1 0 2 0 102 0 1 0 182 M00611(Complex III (Cytochrome bc1 complex)) 679 600 556 721 29 68 215 178 55 101 49 112 93 175 126 162 156 183 147 301 208 163 371 227 206 187 199 192 183 33 156 365 367 257 772 744 138 558 193 252 108 102 0 0 0 0 0 3 3 2 4 113 4 1 0 168 M00610(Complex III (Cytochrome bc1 complex)) 679 600 555 721 29 68 215 178 55 101 49 112 93 175 126 162 156 183 147 301 208 163 371 227 206 187 199 192 183 33 156 365 367 257 772 744 138 558 193 252 108 102 0 0 0 0 0 3 3 2 4 113 4 1 0 168 M00506(Coenzyme A biosynthesis, pantothenate => CoA) 579 446 486 469 51 36 164 135 75 68 68 95 47 182 101 132 225 238 148 180 186 145 322 177 174 478 212 223 173 34 165 277 269 225 774 795 201 999 193 251 110 103 1 1 2 2 0 2 2 2 2 97 0 0 0 166 M00359(Keratan sulfate degradation) 557 344 530 357 140 104 206 164 130 90 100 106 67 226 121 78 170 215 236 175 143 199 305 167 156 456 201 198 139 72 103 302 234 212 652 683 133 914 188 282 126 101 0 0 0 0 0 0 0 0 1 110 2 0 0 152 M00323(CMP-Kdo biosynthesis) 794 481 545 465 53 50 164 169 74 82 74 95 70 154 80 108 149 153 127 179 142 157 340 182 176 251 163 219 152 38 150 298 298 217 627 766 173 892 184 230 113 99 0 1 0 2 2 1 5 0 4 99 0 2 0 149 M00521(Polyamine biosynthesis, arginine => putrescine => spermidine) 982 382 352 458 42 68 106 164 83 43 56 94 63 133 106 119 125 115 108 177 236 191 405 266 235 251 179 170 256 141 251 338 252 161 566 660 122 631 238 206 91 104 0 1 1 0 0 0 0 0 2 106 2 2 2 201 M00105(Aspartate biosynthesis, oxaloacetate => aspartate) 646 380 501 416 49 71 114 118 55 54 76 86 78 163 97 69 206 204 136 197 192 162 324 177 211 464 167 198 195 75 159 314 261 188 522 642 177 960 173 251 116 87 0 0 4 1 0 0 0 1 0 100 0 3 0 178 M00016(Glucuronate pathway (uronate pathway)) 1043 345 394 387 54 53 149 148 52 58 48 75 35 107 99 62 159 205 95 164 187 142 318 183 197 563 133 165 148 62 135 303 257 193 583 528 174 761 226 223 95 109 0 3 5 0 4 3 2 2 6 77 1 0 4 144 M00322(Pentose interconversion, arabinose/ribulose/xylulose/xylose) 1011 384 419 414 66 45 157 122 64 79 53 79 50 132 70 104 182 181 99 133 147 161 287 157 167 492 126 132 135 50 120 299 267 218 725 557 150 601 193 253 95 105 0 1 0 4 0 2 2 3 2 92 1 0 2 138 M00116(Cysteine biosynthesis, serine => cysteine) 790 361 390 390 66 54 158 127 62 66 88 60 38 132 77 96 136 160 116 157 184 164 298 201 220 251 130 145 160 61 152 301 262 134 598 525 115 895 199 203 85 78 0 0 2 0 0 0 0 1 0 89 1 0 1 145 M00419(Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone) 1154 318 450 352 47 41 112 109 64 103 69 76 75 249 114 96 163 149 128 162 124 156 264 136 122 317 147 132 129 25 92 264 269 152 457 471 168 888 171 201 80 101 1 4 0 2 0 0 0 1 4 65 1 4 0 142 M00509(Biotin biosynthesis, pimeloyl-CoA => biotin) 1095 353 395 435 70 68 134 144 64 62 77 92 63 144 110 82 127 114 130 135 215 202 363 195 206 180 138 136 188 58 167 288 197 149 459 628 165 453 243 164 91 72 2 0 0 2 0 2 0 2 2 80 1 4 0 111 M00319(Fucose biosynthesis, GDP-mannose => L-fucose) 466 246 266 358 35 46 118 176 49 49 52 85 55 87 87 75 165 190 99 173 144 171 315 183 200 540 160 200 190 121 164 247 253 192 387 713 193 776 149 161 135 96 0 1 0 0 0 1 0 3 0 71 4 0 0 204 M00013(Glyoxylate biosynthesis, glycolate => glyoxylate) 528 294 318 384 20 41 74 181 57 63 71 98 93 187 130 164 270 215 153 188 130 124 218 136 143 355 207 158 108 20 75 226 199 134 403 505 135 1214 120 90 68 37 0 2 0 0 0 0 0 0 0 30 0 0 0 151 M00136(Methionine biosynthesis, intermediates, homoserine => O-acetylhomoserine => cystathionine) 661 341 356 369 49 52 127 136 55 58 45 94 61 129 94 103 148 181 113 164 151 147 243 167 171 264 125 153 127 35 98 252 191 170 440 630 122 899 193 159 98 111 0 0 1 0 0 1 1 1 0 98 0 1 0 131 M00124(GABA (gamma-Aminobutyrate) shunt) 1109 301 305 274 29 33 95 94 38 65 41 68 38 114 67 87 169 215 87 106 124 113 176 128 105 364 123 134 112 15 101 241 214 180 468 523 113 875 112 197 80 81 0 0 0 0 0 0 0 3 0 80 2 0 2 117 M00411(Eicosanoid biosynthesis, LTA4 => LTC4) 928 433 621 369 44 50 135 112 54 70 39 56 46 217 113 75 69 36 113 144 171 145 297 117 157 183 146 131 154 56 101 212 188 150 497 486 63 465 156 183 52 79 2 1 0 0 2 1 0 1 0 66 1 0 4 124 M00504(Glutathione biosynthesis, glutamate => glutathione) 630 396 376 391 24 48 128 135 39 57 51 96 43 144 93 98 113 102 102 142 141 121 263 179 144 71 123 141 157 27 114 270 230 224 576 430 160 552 144 179 87 92 4 1 0 2 0 2 2 1 5 89 0 2 0 159 M00518(Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => inositol) 409 374 397 377 35 49 133 135 48 70 47 65 43 180 85 84 111 92 101 150 160 144 317 156 191 213 108 153 127 41 141 247 231 175 532 521 155 561 157 165 87 82 0 0 1 2 1 0 3 1 4 92 2 1 2 116 M00519(Inositol phosphate metabolism, Ins(1,4,5)P3 => myo-inositol) 409 374 397 377 35 49 133 135 48 70 47 65 43 180 85 84 111 92 101 150 160 144 317 156 191 213 108 153 127 41 141 247 231 175 532 521 155 561 157 165 87 82 0 0 1 2 1 0 3 1 4 92 2 1 2 116 M00613(Complex IV (Cytochrome c oxidase), cytochrome c oxidase) 431 430 397 412 38 32 133 138 50 60 46 83 50 131 121 83 135 159 114 152 125 154 217 151 167 159 148 165 159 41 108 270 205 151 553 469 86 512 164 221 93 100 0 0 0 2 0 0 0 0 0 81 2 4 0 122 M00306(UDP-Xylose biosynthesis, UDP-Glc => UDP-Xyl => Xyl) 548 309 367 338 53 50 129 134 51 49 44 66 35 86 89 55 118 162 93 152 155 120 277 166 177 381 121 150 134 60 123 247 206 151 449 446 144 587 178 162 79 81 0 3 5 0 4 1 0 1 4 59 0 0 4 133 M00115(Glycine biosynthesis, serine => glycine) 463 324 351 346 29 35 114 100 52 64 55 91 41 113 72 78 135 158 61 116 154 114 278 145 167 328 115 137 148 56 114 234 226 156 438 562 133 665 153 152 76 76 0 2 0 1 0 2 0 3 2 57 0 0 0 84 M00453(Phosphatidylglycerol biosynthesis, CDP-diacylglycerol => phosphatidylglycerol) 423 319 380 344 20 36 103 105 42 37 35 76 31 124 81 78 122 162 85 137 153 121 239 138 151 367 149 171 160 23 111 212 202 155 511 540 135 657 158 137 69 56 0 2 2 0 0 0 0 0 1 78 0 0 0 125 M00625(Reduced pentose phosphate cycle, Glycerate-3P => Glyceraldehyde-3P) 363 343 392 343 37 31 96 96 52 57 52 88 41 91 92 96 131 150 84 125 137 136 240 169 120 245 124 135 133 44 98 199 175 171 463 528 182 581 130 142 84 68 0 1 1 0 0 0 3 2 1 74 0 0 2 141 M00508(Cobalamin biosynthesis, cobinamide => cobalamin) 1020 198 326 339 62 58 71 54 41 42 52 57 61 108 57 50 38 78 71 79 188 170 309 207 225 175 88 135 144 109 199 275 142 111 339 261 92 569 199 176 45 45 2 0 1 1 0 0 0 2 0 67 2 1 0 91 M00423(Triacylglycerol biosynthesis) 530 326 366 300 19 18 122 95 50 37 52 49 33 143 63 64 95 86 95 114 128 112 214 130 109 233 130 135 114 30 123 180 187 120 383 478 95 713 143 112 68 87 0 0 1 2 0 1 2 1 0 46 0 2 2 109 M00424(Phosphatidic acid (PA) biosynthesis) 530 325 365 299 19 18 122 95 50 37 50 49 33 143 63 64 95 86 95 114 128 112 214 130 109 222 130 135 114 30 123 180 187 120 383 478 93 704 143 112 68 87 0 0 1 2 0 1 2 1 0 46 0 2 2 109 M00166(Selenocysteine metabolism) 294 283 390 321 36 32 94 76 67 33 22 72 37 77 99 79 128 81 92 133 154 135 259 165 101 320 114 152 161 24 90 228 194 161 407 500 135 305 147 175 84 81 0 0 0 0 2 0 2 1 0 63 0 5 2 110 M00360(Lipopolysaccharide biosynthesis, inner core => outer core => O-antigen) 523 259 364 297 37 30 77 106 44 39 33 54 43 100 99 47 107 84 69 116 79 92 164 113 95 164 121 130 106 20 82 186 167 140 452 492 137 570 99 136 60 92 0 1 1 0 1 0 0 1 0 74 0 0 1 108 M00458(Plasmenylethanolamine biosynthesis) 428 301 345 285 18 15 107 91 48 37 46 48 30 132 63 61 91 86 84 101 125 108 191 126 98 210 118 121 104 29 120 163 179 110 346 454 90 667 137 105 64 87 0 0 1 2 0 1 2 1 0 42 0 0 2 102 M00008(Entner-Doudoroff pathway) 753 154 104 159 40 40 68 70 25 43 85 68 34 138 91 89 122 87 105 157 102 73 160 112 136 165 157 108 93 71 98 182 122 141 330 257 187 581 208 101 97 41 0 2 0 0 0 0 0 0 0 51 0 0 0 225 M00324(ADP-L-glycero-D-manno-heptose biosynthesis) 466 197 345 224 20 40 86 102 37 60 49 44 48 114 66 71 118 104 82 124 110 126 200 134 129 319 101 109 111 42 72 189 143 135 220 447 171 422 89 127 63 42 0 0 2 0 0 0 0 0 0 28 1 0 1 115 M00006(Pentose phosphate pathway, oxidative phase) 596 137 93 155 23 30 68 84 25 41 50 49 30 82 76 65 98 94 82 185 93 86 190 117 139 192 137 112 89 90 85 177 117 139 250 200 169 670 246 91 133 35 1 2 0 0 0 0 0 1 0 52 0 0 0 295 M00162(Tyrosine degradation, tyrosine => homogentisate) 1116 206 260 268 18 39 66 110 47 28 40 47 54 107 42 62 104 91 101 100 112 83 207 116 122 182 106 79 78 23 64 160 126 84 239 290 97 491 94 127 42 25 0 0 0 0 0 0 0 0 0 37 1 0 0 76 M00520(Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate) 417 193 333 220 84 94 60 49 42 20 43 40 26 157 70 50 100 97 108 84 87 101 143 74 57 277 86 90 72 98 56 104 104 85 209 339 235 1050 70 110 67 32 0 0 0 2 0 0 2 0 0 38 3 0 0 83 M00620(Photosystem II) 272 78 60 217 50 46 43 126 21 28 3 11 69 0 4 2 2 8 24 82 277 171 489 286 309 162 89 164 298 392 227 222 76 74 106 93 8 382 363 75 75 84 2 0 3 0 7 4 0 1 0 98 0 5 2 195 M00106(Asparagine biosynthesis, aspartate => asparagine) 383 214 319 279 35 38 74 68 40 40 24 48 25 89 79 55 60 63 72 102 141 87 217 96 123 128 115 90 93 33 80 179 154 158 296 484 170 353 138 154 65 73 0 2 0 0 0 4 2 1 0 61 0 0 6 103 M00604(Complex I (NADH dehydrogenase), NADH dehydrogenase I/diaphorase subunit of the bidirectional hydrogenase) 447 107 52 299 43 70 27 8 3 11 0 12 5 14 8 12 15 18 13 52 279 164 471 252 283 116 91 113 204 230 283 257 91 95 113 117 15 630 351 57 51 48 0 0 0 1 1 0 7 6 0 83 1 2 2 80 M00435(C10 isoprenoid biosynthesis) 276 251 292 286 39 32 63 95 47 55 38 41 26 109 87 49 88 91 78 122 79 92 209 96 144 106 84 124 95 51 83 180 138 103 358 410 73 384 121 113 52 95 0 1 0 0 2 0 2 1 0 49 0 1 0 87 M00436(C15 isoprenoid biosynthesis) 276 251 292 286 39 32 63 95 47 55 38 41 26 109 87 49 88 91 78 122 79 92 209 96 144 106 84 124 95 51 83 180 138 103 358 410 73 384 121 113 52 95 0 1 0 0 2 0 2 1 0 49 0 1 0 87 M00168(beta-Alanine biosynthesis, cytosine / uracil => beta-alanine) 621 204 269 260 23 48 74 63 23 30 30 20 42 135 24 40 62 89 75 75 99 94 159 105 110 318 93 68 60 35 69 114 98 72 277 278 54 532 100 83 30 41 0 0 0 0 0 0 0 0 0 46 0 0 0 51 M00428(Phosphatidylethanolamine (PE) biosynthesis, PS => PE) 289 185 237 190 19 19 56 83 32 28 31 48 30 83 75 45 76 56 59 73 56 102 120 79 48 90 72 69 73 16 65 125 129 101 277 339 61 168 74 109 60 46 0 0 0 0 0 1 0 1 0 34 0 0 0 47 M00305(UDP-N-Acetylgalactosamine and UDP-N-acetylmannosamine biosynthesis) 185 161 224 170 24 24 68 38 26 12 15 30 14 38 48 38 82 52 57 69 81 65 148 92 76 142 88 99 82 19 76 125 100 98 240 346 76 322 80 82 59 22 4 1 0 0 0 0 0 0 0 36 0 0 0 64 M00439(C40 isoprenoid biosynthesis, GGAP => lycopene) 253 153 90 216 14 33 33 44 17 19 8 35 11 31 31 26 64 56 23 56 110 58 207 100 116 106 59 69 99 79 75 146 105 84 185 149 51 356 169 71 32 39 0 0 0 0 3 1 0 2 0 37 0 1 2 71 M00101(Glutamate biosynthesis, oxoglutarate => glutamate (glutamate dehydrogenase)) 146 110 192 110 41 8 41 29 30 24 50 30 24 54 36 27 50 70 50 70 55 76 112 46 56 157 64 63 70 20 40 104 80 65 233 214 111 647 52 96 41 42 2 0 1 0 0 0 0 1 0 30 0 0 2 71 M00163(Histidine degradation, histidine => N-formiminoglutamate => glutamate) 820 96 173 50 9 6 4 21 34 16 37 16 41 70 22 26 104 106 34 62 47 89 105 42 45 272 39 53 43 21 29 71 54 48 99 164 42 396 26 93 30 34 0 0 1 0 0 0 0 0 0 27 0 0 2 48 M00447(CDP-diacylglycerol biosynthesis, PA => CDP-diacylglycerol) 263 146 166 172 16 18 43 73 30 24 19 31 20 59 43 41 75 68 50 71 87 52 116 64 68 113 68 69 59 19 44 117 97 67 225 221 76 397 64 70 32 31 0 0 0 0 0 1 0 0 0 27 0 0 0 50 M00618(V-type ATPase (Prokaryotes)) 38 109 237 94 20 13 32 37 18 8 3 43 31 81 60 34 28 34 30 83 61 102 136 50 52 155 56 75 63 32 35 92 118 62 110 209 197 429 46 110 77 75 0 0 0 0 0 0 0 0 0 20 0 0 0 112 M00358(Heparan sulfate degradation) 71 40 74 62 95 95 59 91 33 45 45 14 68 98 36 30 29 20 89 56 42 85 96 43 39 62 75 55 43 41 34 113 76 59 249 224 24 273 51 110 30 47 0 0 2 0 0 0 0 0 0 53 0 0 0 33 M00515(Ubiquinone biosynthesis, chorismate => ubiquinone, eukaryotes) 256 186 149 178 6 16 42 55 16 20 22 49 16 73 32 30 46 43 38 45 48 42 116 50 61 29 57 59 51 9 48 103 91 72 245 225 36 157 52 74 30 30 0 0 0 2 0 0 0 0 0 24 1 1 0 40 M00123(Selenocysteinyl-tRNA biosynthesis) 270 66 193 106 14 20 31 15 18 15 8 10 17 38 35 30 25 26 46 33 88 78 172 84 62 70 75 79 83 37 82 78 57 50 117 177 25 357 73 41 34 23 0 2 0 0 3 0 0 0 0 30 0 2 0 59 M00430(Phosphatidylserine (PS) biosynthesis, CDP-diacylglycerol => PS) 216 153 145 148 8 14 37 69 28 31 28 44 17 64 46 49 67 48 65 40 52 51 83 45 42 66 47 39 56 10 41 77 87 85 256 230 56 110 60 65 34 43 1 0 1 0 0 2 0 1 0 33 0 1 2 50 M00321(Uronic acid metabolism) 240 95 105 88 39 23 41 52 23 27 18 27 30 53 37 45 116 104 47 55 38 65 85 47 39 155 50 30 38 7 30 80 88 81 182 163 45 88 36 70 28 30 0 1 1 2 2 2 0 0 0 17 0 0 0 40 M00522(Polyamine biosynthesis, ornithine => putrescine) 323 153 99 160 5 1 37 37 18 13 22 33 9 10 21 34 61 46 31 56 44 62 93 58 73 51 40 45 48 2 44 81 69 58 159 259 35 178 49 47 22 21 0 0 0 0 0 2 0 0 0 32 0 0 0 50 M00141(Threonine biosynthesis, glycine => threonine) 164 71 89 82 12 21 27 60 31 24 15 17 22 81 42 41 62 57 48 62 40 57 94 59 35 141 60 46 43 19 22 80 70 80 151 189 40 250 45 68 33 28 0 0 0 0 1 0 0 2 2 24 0 0 0 60 M00622(Photosystem I) 197 69 21 177 34 32 14 4 1 7 1 0 1 2 0 4 0 3 8 14 185 71 209 126 150 3 28 76 103 123 132 119 21 22 63 13 2 244 178 22 11 72 0 0 0 0 0 0 0 5 0 101 3 1 1 1 M00173(Creatine pathway) 120 170 127 174 3 11 50 61 13 27 14 26 36 37 38 53 26 27 17 70 72 44 61 48 59 26 52 38 46 0 28 94 71 73 192 257 42 26 44 58 25 18 0 0 0 0 0 0 0 1 0 24 0 0 0 46 M00130(Asparagine degradation, asparagine => aspartate +NH3) 253 92 157 63 26 10 25 21 29 8 26 33 17 42 23 22 30 47 29 47 41 45 75 38 18 53 37 44 34 18 32 101 79 46 118 149 118 155 65 97 44 43 0 0 0 0 0 1 0 0 0 20 0 0 0 41 M00356(Dermatan sulfate degradation) 61 47 75 46 88 77 67 84 29 46 27 9 59 85 31 34 25 16 57 40 35 59 71 39 38 50 55 38 44 28 37 88 68 40 192 173 24 151 48 73 23 35 0 0 2 0 0 0 0 0 0 44 0 0 0 20 M00129(Aspartate degradation, aspartate => oxaloacetate) 193 41 40 57 22 12 31 27 17 11 20 17 16 37 27 24 68 73 29 29 64 32 82 34 52 159 31 21 45 26 40 67 32 39 45 78 47 406 46 30 28 16 2 4 0 0 0 2 0 0 0 12 0 0 0 23 M00131(Lysine biosynthesis, 2-oxoglutarate => 2-aminoadipate => lysine) 665 52 99 58 14 12 21 22 12 14 22 14 18 45 29 27 17 16 35 20 24 13 48 21 33 12 38 31 14 9 23 71 71 41 152 124 40 59 32 66 23 28 0 0 0 1 0 0 0 0 0 15 2 0 0 27 M00634(Methanogenesis) 135 103 154 110 3 5 9 19 13 19 4 11 19 27 31 19 31 18 18 36 26 44 45 36 27 119 28 27 29 3 16 45 59 37 98 233 29 191 27 48 14 12 0 0 0 1 1 0 0 0 0 25 0 0 0 22 M00609(Complex II (succinate dehydrogenase / fumarate reductase), fumarate reductase) 439 84 141 61 12 9 16 9 19 7 5 13 14 50 9 7 23 27 14 28 20 28 63 22 20 41 41 20 24 10 13 48 40 38 92 74 18 90 35 66 20 14 0 1 0 0 0 0 0 0 0 21 0 1 0 28 M00433(C5 isoprenoid biosynthesis, mevalonate pathway) 28 54 122 35 11 10 19 11 20 20 20 11 7 70 34 14 14 19 20 42 23 53 65 27 22 61 39 20 17 18 24 58 55 42 68 89 88 319 25 61 36 25 0 0 0 0 0 0 1 1 0 11 0 1 0 45 M00152(Tryptophan metabolism, kynurenine => 2-aminomuconate) 171 33 116 50 23 11 11 17 18 11 35 21 11 51 20 18 61 87 38 32 21 30 57 21 21 127 32 19 18 5 2 41 39 17 69 143 22 255 15 37 12 6 0 0 0 0 0 0 0 0 0 8 0 0 1 15 M00445(Acylglycerol degradation) 399 54 108 57 12 6 19 43 11 13 22 10 11 38 22 23 52 41 24 19 42 22 57 31 38 69 13 13 33 20 38 36 23 16 64 68 25 140 23 35 7 12 0 0 1 0 0 0 2 0 0 12 0 1 0 14 M00119(Phenylalanine biosynthesis, chorismate => phenylalanine) 320 70 37 74 4 13 17 18 13 13 14 13 10 49 27 14 34 24 31 32 17 28 31 41 23 13 41 30 28 4 24 57 59 44 127 117 34 66 30 54 18 34 0 0 0 0 0 0 0 0 0 24 0 0 1 36 M00526(Flavonoid biosynthesis, naringenin => pelargonidin 3-O-glucoside) 117 85 77 57 6 10 49 28 23 12 11 8 12 26 12 18 16 9 8 47 34 41 88 42 29 6 41 45 47 6 14 55 64 39 85 107 12 143 37 69 22 25 0 0 0 0 0 0 0 0 0 34 0 0 0 50 M00167(beta-Alanine biosynthesis, L-aspartate => beta-alanine) 56 34 36 33 30 10 42 24 30 12 19 24 15 29 32 14 27 7 27 22 29 50 46 26 33 17 25 32 29 6 27 68 37 25 172 135 44 236 23 88 18 20 0 1 0 0 0 0 0 0 0 17 0 0 0 20 M00153(Lignin biosynthesis, 4-hydroxycinnamyl alcohol => lignin) 204 84 78 65 4 6 13 12 5 5 7 10 7 44 13 13 23 36 21 17 20 34 45 25 24 53 19 11 20 7 16 26 15 16 28 136 43 371 10 3 6 12 0 0 0 0 0 0 0 0 0 9 0 0 0 10 M00155(Lignin biosynthesis, sinapyl alcohol => lignin) 204 84 78 65 4 6 13 12 5 5 7 10 7 44 13 13 23 36 21 17 20 34 45 25 24 53 19 11 20 7 16 26 15 16 28 136 43 371 10 3 6 12 0 0 0 0 0 0 0 0 0 9 0 0 0 10 M00154(Lignin biosynthesis, coniferyl alcohol => lignin) 204 84 78 65 4 6 13 12 5 5 7 10 7 44 13 13 23 36 21 17 20 34 45 25 24 53 19 11 20 7 16 26 15 16 28 136 43 371 10 3 6 12 0 0 0 0 0 0 0 0 0 9 0 0 0 10 M00612(Cytochrome bd complex) 732 28 11 6 6 2 3 1 1 0 4 3 0 9 8 9 37 35 5 0 5 4 4 4 2 72 15 3 3 1 6 6 11 8 6 14 51 410 2 12 8 2 0 0 0 0 0 0 0 0 0 3 0 0 0 5 M00635(Nitrogen fixation, N2 => ammonia) 48 49 50 38 3 5 20 20 13 7 9 11 7 31 9 12 9 8 22 24 17 19 56 15 28 16 33 41 25 6 11 49 39 34 135 80 32 239 20 47 16 21 0 0 0 0 1 0 0 2 0 15 0 1 0 25 M00530(Tetrahydrofolate biosynthesis) 102 51 51 45 11 17 19 17 12 9 13 7 21 48 22 19 28 34 28 23 21 20 50 13 24 37 13 34 22 10 16 42 39 34 57 95 44 131 18 34 20 16 0 0 1 0 0 0 0 0 0 18 0 0 0 13 M00413(Ciliatine metabolism, phosphoenolpyruvate => ciliatine => ceramide ciliatine) 230 38 83 50 5 4 5 17 15 6 9 10 3 23 28 13 28 19 22 25 20 16 42 17 16 65 26 23 26 13 10 33 36 26 55 79 44 75 21 20 10 12 0 0 0 0 0 0 0 0 2 9 0 0 0 39 M00132(Lysine biosynthesis, 2-oxoglutarate => 2-aminoadipate => lysine) 587 50 81 43 1 1 3 4 6 1 6 17 13 16 24 9 4 7 18 7 5 7 4 10 12 77 16 0 3 1 4 14 13 7 50 33 56 34 5 12 8 3 0 0 0 0 0 0 0 0 0 1 0 0 0 8 M00407(Eicosanoid biosynthesis, PGH2 => PGF2alpha) 398 49 57 37 2 2 9 20 8 10 13 11 6 28 13 12 30 15 21 22 27 14 25 22 23 54 14 13 12 5 6 33 13 18 48 61 9 46 7 26 5 5 0 0 0 0 0 1 1 0 0 12 0 0 0 10 M00437(C20 isoprenoid biosynthesis) 45 55 67 79 7 9 6 17 8 11 11 3 1 27 18 7 12 12 17 30 22 30 68 31 59 45 12 26 16 24 23 38 28 11 39 49 13 167 22 18 10 16 0 1 0 0 0 0 2 1 0 16 0 0 0 15 M00624(Reduced pentose phosphate cycle, RuBP + CO2 => Glycerate-3P) 44 27 15 51 8 11 6 1 1 4 4 2 0 20 2 11 6 10 8 7 41 25 66 37 45 17 8 10 42 45 46 38 17 7 27 50 22 391 26 9 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 3 M00621(Cytochrome b6f complex) 92 26 11 76 8 17 6 0 1 0 0 0 2 7 3 2 2 15 4 2 96 65 66 57 75 30 10 13 36 38 68 52 11 11 24 9 7 137 45 7 8 4 0 0 2 0 0 0 0 2 0 7 0 0 0 10 M00615(Complex IV (Cytochrome c oxidase), cytochrome c oxidase, cbb3-type) 157 13 13 5 0 0 4 1 3 2 5 8 6 52 10 10 39 34 16 6 12 13 12 13 15 48 40 12 10 0 4 10 10 25 17 43 58 345 12 8 5 2 0 0 0 0 0 0 0 0 0 5 0 0 0 31 M00157(Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine) 119 49 39 41 4 12 10 7 6 7 6 2 5 23 4 7 14 9 14 15 13 6 23 19 11 19 21 25 20 1 19 27 34 25 61 58 10 44 18 10 7 10 0 0 0 0 0 0 2 0 0 15 0 0 0 13 M00357(Chondroitin sulfate degradation) 27 27 36 21 6 14 25 26 12 12 4 1 21 36 22 25 10 9 27 22 12 15 20 14 17 29 27 18 10 3 11 36 24 12 64 59 10 55 23 16 13 10 0 0 0 0 0 0 0 0 0 8 0 0 0 8 M00472(Conjugated bile acid biosynthesis, choloyl-CoA => taurocholate/glycocholate) 80 35 43 28 6 12 10 6 3 5 3 8 8 14 8 15 12 9 17 15 14 23 31 18 21 13 14 21 15 3 9 20 34 16 24 36 16 145 9 12 24 7 0 0 0 0 0 0 0 0 0 5 0 0 0 18 M00459(Plasmenylcholine biosynthesis) 846 3 7 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 3 0 4 0 0 1 0 0 0 2 0 0 0 0 0 0 3 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00122(Glutamine degradation, glutamine => glutamate + NH3) 99 26 20 26 16 2 15 16 16 4 13 19 9 19 5 12 7 19 9 13 2 12 19 12 15 7 11 14 13 14 4 27 17 25 64 54 12 56 5 34 10 9 0 0 0 0 0 0 0 0 0 7 0 0 0 3 M00148(Cysteine metabolism, cysteine => pyruvate) 34 29 35 55 4 3 19 14 4 4 7 11 1 15 14 6 4 5 17 16 27 15 47 36 29 6 16 24 29 12 22 18 8 15 26 47 9 38 11 10 9 11 0 0 0 0 0 0 0 0 0 9 0 1 0 18 M00429(Eicosanoid biosynthesis, arachidonate => 14,15-EET / 11,12-EET / 8,9-EET / 5,6-EET) 32 48 64 43 2 2 26 18 1 9 8 4 6 28 6 4 3 2 5 13 16 29 40 18 30 9 6 24 14 3 12 22 17 22 37 52 0 20 9 13 6 9 0 0 0 0 0 0 0 0 0 13 0 0 0 6 M00169(Carnosine / anserine biosynthesis) 64 19 81 16 12 8 12 7 8 9 10 9 3 10 4 8 4 15 9 11 12 28 52 18 10 19 3 7 7 0 6 21 8 8 47 39 2 34 16 27 6 3 0 0 0 0 0 0 0 0 0 3 0 0 0 6 M00170(Taurine biosynthesis, cysteine => hypotaurine => taurine) 10 13 22 13 11 4 14 8 7 4 8 6 3 7 10 2 3 0 10 8 15 24 12 9 4 2 17 10 11 4 11 29 12 19 67 63 7 123 11 45 9 7 0 0 0 0 0 0 0 0 0 12 0 0 0 4 M00014(Glyoxylate biosynthesis, glycine => glyoxylate) 149 21 23 33 5 6 7 13 0 2 0 1 0 3 3 2 4 3 4 22 24 12 35 17 28 5 6 10 16 14 23 21 11 4 29 13 8 45 27 4 5 2 0 0 0 0 0 0 0 0 0 7 0 0 0 1 M00476(Androgen and estrogen biosynthesis, pregnenolone => estrone <=> estradiol) 260 21 37 24 2 7 2 5 4 4 6 5 4 13 8 8 4 2 9 5 1 5 19 5 8 4 8 7 4 5 6 18 6 10 17 22 8 56 6 3 3 9 0 0 0 0 0 0 0 0 0 4 1 0 0 2 M00171(Taurine biosynthesis, cysteine => cysteate => taurine) 10 10 12 11 11 4 14 8 7 4 5 6 3 6 10 2 3 0 9 4 15 17 8 6 3 2 7 8 9 4 9 27 11 17 65 63 7 123 11 43 8 7 0 0 0 0 0 0 0 0 0 12 0 0 0 4 M00144(Serine biosynthesis, hydroxypyruvate => serine) 131 42 29 34 2 1 2 9 7 6 2 3 0 23 7 3 6 5 12 5 6 8 24 8 4 6 2 3 2 8 5 7 14 11 26 32 7 31 6 4 0 6 0 0 0 0 0 0 0 0 0 3 0 0 0 4 M00159(Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline) 167 6 45 15 4 3 1 0 2 0 4 0 1 17 2 0 2 0 5 13 13 10 12 2 5 14 8 4 13 2 5 9 10 5 32 45 1 21 2 11 0 6 0 0 0 0 0 0 0 0 0 5 0 0 0 4 M00425(Phosphatidylcholine (PC) biosynthesis, choline => PC) 13 22 17 8 2 1 17 7 4 2 0 5 5 6 14 14 4 0 8 15 10 10 23 11 14 20 13 13 11 0 7 16 17 14 31 24 4 2 21 21 6 8 0 0 0 0 0 0 0 0 0 1 0 0 0 22 M00164(Histidine metabolism, histidine => histamine) 96 7 45 15 3 3 1 0 2 0 4 0 1 16 2 0 0 1 5 13 13 10 12 3 5 14 8 4 13 0 5 9 11 5 32 45 6 17 2 11 0 6 0 0 0 0 0 0 0 0 0 5 0 0 0 4 M00149(Tryptophan metabolism, tryptophan => tryptamine) 96 6 45 15 3 3 1 0 2 0 4 0 1 16 2 0 0 0 5 13 13 10 12 2 5 13 8 4 13 0 5 9 10 5 32 45 1 12 2 11 0 6 0 0 0 0 0 0 0 0 0 5 0 0 0 4 M00517(Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1.3.4.5)P4) 8 12 51 12 3 5 4 3 14 4 3 5 4 3 12 9 1 6 8 11 6 8 24 8 12 3 6 10 9 5 1 15 4 4 22 29 7 31 1 19 5 2 0 0 0 0 0 0 0 0 0 5 0 0 0 7 M00477(Androgen and estrogen biosynthesis, pregnenolone => testosterone -> estradiol) 63 15 31 23 1 7 2 5 4 3 6 3 4 11 4 5 2 2 7 2 1 2 12 3 8 1 6 6 3 5 4 16 6 8 15 19 8 37 5 3 2 7 0 0 0 0 0 0 0 0 0 0 1 0 0 0 M00440(C40 isoprenoid biosynthesis, lycopene => beta-carotene) 24 6 3 20 1 5 1 4 0 0 0 0 1 0 0 0 0 0 0 8 22 8 34 21 33 12 1 12 19 23 20 9 1 2 4 0 0 49 25 0 0 4 0 0 0 0 0 0 0 0 0 5 0 0 0 0 M00156(Tyrosine biosynthesis, phenylalanine => tyrosine) 107 6 32 3 1 1 3 1 2 6 1 1 0 5 10 0 6 2 3 6 0 11 4 3 9 8 5 2 4 2 3 18 2 2 24 28 12 13 3 8 4 6 0 0 0 0 0 0 0 0 0 2 0 0 0 0 M00454(Diphosphatidylglycerol biosynthesis, CDP-glycerol => cardiolipin) 188 1 1 1 1 1 2 0 1 1 4 1 0 3 0 0 14 1 2 1 0 0 0 0 0 19 2 0 2 0 0 1 0 0 3 5 6 40 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 M00352(N-glycan biosynthesis, ER lumen) 12 10 19 6 0 5 3 2 1 0 1 3 0 1 3 0 5 2 1 4 8 9 8 4 9 10 4 12 6 8 4 8 7 4 6 20 18 11 2 4 5 0 0 0 0 0 0 0 0 0 0 3 0 0 0 5 M00128(Aspartate degradation, aspartate => fumarate) 66 1 2 0 0 0 0 0 0 0 1 5 0 4 5 0 6 4 8 3 0 0 1 0 0 13 1 0 0 0 2 1 0 0 2 3 8 112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00438(C30 isoprenoid biosynthesis) 28 2 8 2 0 0 0 0 0 0 0 0 0 16 4 3 1 4 1 5 13 7 14 3 9 4 6 3 7 2 2 12 4 4 0 9 2 2 0 5 10 0 0 0 0 0 0 0 0 0 0 1 0 0 0 7 M00525(Flavonoid biosynthesis, 4-coumaroyl-CoA => naringenin => apigenin) 3 1 0 0 3 7 6 3 2 0 0 0 1 3 0 0 0 2 5 0 0 0 0 3 1 0 1 0 1 0 0 3 3 0 2 3 3 112 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00172(Isethionate biosynthesis, taurine <=> isethionate) 0 2 2 4 0 0 1 2 1 0 3 1 2 7 2 3 0 0 6 0 2 0 0 1 2 0 0 2 0 0 0 9 12 8 21 21 1 11 6 10 0 2 0 0 0 2 0 0 0 0 0 2 0 0 0 9 M00473(Corticoid biosynthesis, cholesterol => prognenolone => progesterone) 2 2 0 6 0 7 2 5 2 0 0 2 2 6 2 3 1 2 2 1 0 2 7 2 3 1 1 1 2 4 4 6 4 4 5 4 8 34 1 3 1 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 M00328(Lactosylceramide biosynthesis) 139 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00410(Eicosanoid biosynthesis, LTA4 => LTB4) 10 12 3 0 2 2 1 0 9 2 0 5 3 4 0 1 3 2 2 0 0 1 2 2 2 4 3 1 1 1 0 10 8 2 4 6 4 7 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00127(Arginine degradation, arginine => citrulline) 12 1 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 2 2 0 7 1 0 0 0 1 1 1 0 5 11 2 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00449(Phosphatidylethanolamine (PE) degradation, PE => PA) 115 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00448(Phosphatidylcholine (PC) degradation) 115 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00426(Phosphatidylcholine (PC) biosynthesis, PE => PC) 5 3 5 6 1 1 1 2 0 0 0 0 0 0 0 0 0 0 3 1 2 3 5 7 3 3 0 2 2 1 4 6 2 2 2 9 2 11 1 2 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 M00465(C30 isoprenoid biosynthesis, squalene => lanosterol) 7 3 9 5 0 1 0 0 0 0 0 0 0 2 1 0 0 0 2 1 2 0 2 0 2 2 0 1 0 4 2 4 0 0 0 4 1 32 1 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00529(Alkaloid biosynthesis, dopamine => (S)-reticuline => morphine/dihydrosanguinarine/macarpine) 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00158(Tyrosine metabolism, tyrosine => L-DOPA => dopaquinone => melanin) 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00316(Glycosaminoglycan biosynthesis, chondroitin sulfate backbone) 1 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 4 2 0 4 6 7 9 4 0 1 0 0 4 3 0 5 0 0 0 2 1 5 2 0 4 2 0 0 0 0 0 0 0 0 0 3 0 0 0 1 M00304(N-glycan biosynthesis, cytosol) 5 3 10 7 0 3 0 0 0 0 0 0 0 2 2 0 0 0 0 1 0 0 1 0 0 8 2 0 0 2 0 0 0 0 2 5 10 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 M00467(Choresterol biosynthesis) 0 2 2 0 0 0 0 0 0 0 0 0 0 4 0 1 2 0 1 2 1 3 0 2 3 0 2 5 0 2 0 2 3 0 0 8 0 9 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 M00460(Sphingosine biosynthesis) 0 1 2 2 1 1 0 1 1 0 0 0 0 0 0 0 0 0 1 3 0 0 2 0 0 1 0 0 0 0 0 5 3 2 8 2 0 3 2 4 3 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 M00431(Ceramide biosynthesis) 0 1 2 2 1 1 0 1 1 0 0 0 0 0 0 0 0 0 1 3 0 0 2 0 0 1 0 0 0 0 0 5 3 2 8 2 0 3 2 4 3 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 M00607(Complex II (succinate dehydrogenase / fumarate reductase), succinate dehydrogenase (ubiquinone)) 1 0 0 2 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 4 3 5 0 2 7 2 1 2 3 0 0 0 10 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 M00427(Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE) 0 1 4 0 3 3 0 1 0 0 0 0 0 0 2 0 1 1 2 0 2 1 2 2 0 2 1 0 0 8 2 0 1 0 2 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00461(Sphingosine degradation) 0 0 2 3 0 1 0 0 0 0 0 0 0 2 0 0 0 8 4 2 0 0 2 0 0 10 0 0 0 2 0 2 0 2 2 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 M00151(Tryptophan metabolism, tryptophan => kynurenine => kynurenate) 0 1 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2 1 0 2 0 0 2 1 2 0 0 1 0 0 0 4 0 1 14 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00475(Corticoid biosynthesis, progesterone => cortisol/cortisone) 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 4 0 0 0 0 0 1 1 0 1 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00463(Sphingomyelin metabolism) 0 0 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 2 0 0 1 2 1 0 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 M00110(Alanine biosynthesis, pyruvate => alanine) 0 1 11 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00353(N-glycan biosynthesis, cis-Golgi) 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00354(N-glycan biosynthesis, high-mannose type) 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00444(Linoleic acid metabolism, linoleate => 13(S)-HPODE/9(S)-HPODE) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00457(Platelet-activating factor (PAF) degradation, PAF => lyso PAF) 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 1 1 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00421(Eicosanoid biosynthesis, arachidonate => 15(S)-HPETE / 12(S)-HPETE) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00420(Eicosanoid biosynthesis, linoleate => arachidonate) 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00362(Pectin degradation) 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00456(Platelet-activating factor (PAF) biosynthesis, alkylacetylglycerol => PAF) 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00320(Sucrose synthesis, UDP-glucose + fructose => sucrose) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 M00325(GPI-anchor biosynthesis, cytoplasmic leaflet) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0