GS000_S13_S11a GS000_S13_S11b GS000_S03 GS000_S13 GS001a GS001b GS001c GS002 GS003 GS004 GS005 GS006 GS007 GS008 GS009 GS010 GS011 GS012 GS013 GS014 GS015 GS016 GS017 GS018 GS019 GS020 GS021 GS022 GS023 GS025 GS026 GS027 GS028 GS029 GS030 GS031 GS032 GS033 GS034 GS035 GS036 GS037 GS038 GS039 GS040 GS041 GS042 GS043 GS044 GS045 GS046 GS047 GS048 GS049 GS050 GS051 COG1028(Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)) 9132 3239 3965 3359 337 416 963 1044 503 634 385 533 522 1627 821 806 1020 985 1117 1292 1275 1256 2311 1349 1399 2061 1270 1212 1098 445 918 2193 1701 1346 4189 4669 888 5430 1322 1554 672 678 2 14 3 5 12 9 11 8 2 599 6 13 3 1052 COG0642(Signal transduction histidine kinase) 19442 2451 1942 2099 259 299 552 575 254 309 457 371 231 1036 404 462 955 1097 646 728 807 765 1330 843 861 1873 855 679 661 368 646 1121 923 645 1841 2271 2288 8920 823 823 335 351 9 0 4 0 5 2 9 11 10 354 1 2 9 500 COG2202(FOG: PAS/PAC domain) 24799 1658 1266 1175 157 152 315 317 126 239 338 171 141 670 307 330 725 912 382 410 427 452 726 493 458 1496 657 371 305 201 361 551 556 311 988 1197 2117 6730 424 478 154 174 10 1 0 0 2 4 2 4 2 138 0 0 1 311 COG0477(Permeases of the major facilitator superfamily) 14414 1709 2424 1888 214 298 509 555 290 277 264 272 273 1272 492 455 1125 1189 785 844 750 721 1326 677 714 2280 694 628 553 225 441 1043 891 700 1987 2501 667 4778 733 804 356 343 2 3 4 3 4 3 1 2 0 296 2 0 3 581 COG1012(NAD-dependent aldehyde dehydrogenases) 5684 2024 2109 1813 165 227 568 732 409 390 327 446 417 750 443 468 811 848 655 810 609 587 1114 692 638 1578 749 686 611 148 516 1344 1204 923 2697 3270 593 3515 790 956 411 460 0 7 9 3 3 8 5 12 4 452 4 4 2 661 COG0697(Permeases of the drug/metabolite transporter (DMT) superfamily) 3690 2136 1762 2196 142 280 635 874 388 367 236 492 271 740 485 561 678 702 616 853 744 743 1292 938 847 915 798 795 761 139 694 1436 1340 1099 3168 3476 643 2315 950 1013 454 486 5 3 3 2 4 6 3 5 3 475 3 3 4 783 COG0665(Glycine/D-amino acid oxidases (deaminating)) 4049 1950 1582 1994 106 198 564 777 355 331 258 472 304 896 405 566 517 487 641 891 689 606 1108 666 663 626 748 689 570 115 495 1357 1223 928 2759 3771 545 2341 986 1037 406 433 0 9 5 6 4 9 1 9 1 402 4 3 2 661 COG1629(Outer membrane receptor proteins, mostly Fe transport) 5459 2802 3429 1872 370 183 681 562 351 440 381 242 279 942 382 347 288 243 536 636 638 650 1238 627 651 509 528 465 490 245 412 1087 774 618 2237 1923 348 1722 516 826 295 364 7 3 2 3 2 2 4 4 7 269 0 2 0 264 COG1960(Acyl-CoA dehydrogenases) 4480 1560 2175 1570 201 166 595 522 349 262 284 253 301 1040 385 457 433 424 710 758 619 683 1226 618 679 1156 712 651 603 181 414 1136 933 717 2088 2695 345 2528 632 815 390 418 5 2 3 1 1 1 4 4 0 360 1 7 2 512 COG0451(Nucleoside-diphosphate-sugar epimerases) 2413 1239 1483 1669 146 250 482 644 212 225 173 292 177 436 375 337 622 605 382 735 772 813 1532 875 874 1796 668 783 816 461 688 1102 1007 720 1814 2486 666 2458 747 790 388 417 8 7 3 5 6 2 6 4 0 351 9 1 2 702 COG0438(Glycosyltransferase) 3637 1331 1512 1474 189 170 469 441 207 216 164 279 152 427 379 260 702 697 381 579 707 588 1128 683 633 1615 562 636 544 176 528 943 793 655 1664 2060 880 4819 754 642 303 240 1 6 1 2 0 2 5 8 0 299 3 3 6 516 COG0457(FOG: TPR repeat) 3807 1545 1989 1730 282 363 403 553 274 237 218 309 246 694 394 299 507 512 430 540 674 655 1218 624 780 874 555 610 571 332 548 995 861 658 1964 2434 706 2751 702 788 303 330 7 6 4 5 2 6 1 8 0 285 0 4 1 397 COG0404(Glycine cleavage system T protein (aminomethyltransferase)) 1675 1904 1624 2038 95 151 596 758 317 284 229 406 255 623 388 496 410 418 519 825 695 590 1035 695 641 422 589 599 519 81 458 1197 1054 858 2623 3513 489 1588 869 905 376 481 6 8 4 0 2 6 4 6 0 393 1 1 4 599 COG0842(ABC-type multidrug transport system, permease component) 5464 1165 1269 1193 75 172 399 466 171 185 159 199 157 621 308 287 590 705 395 620 553 585 892 536 660 1483 531 484 388 141 425 844 678 592 1630 1958 559 4551 641 753 284 332 0 6 8 0 0 2 7 1 3 269 5 3 3 482 COG0318(Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II) 6771 1224 1606 1175 159 204 399 462 211 228 242 238 253 860 337 341 360 401 573 607 482 504 970 512 556 860 516 468 428 165 389 838 731 457 1488 1967 431 2998 466 676 244 294 4 6 2 2 0 3 8 3 0 258 4 1 1 348 COG0596(Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)) 4469 1481 1721 1487 167 194 431 492 255 276 244 286 205 711 392 352 447 450 546 540 545 561 1061 587 609 837 491 527 472 194 431 977 741 638 1814 2320 381 2717 622 698 255 261 7 7 7 2 1 1 1 2 2 286 2 5 2 415 COG1024(Enoyl-CoA hydratase/carnithine racemase) 3602 1349 1741 1394 126 171 387 427 229 282 227 240 263 826 334 330 370 369 539 663 567 606 1079 599 608 747 599 510 480 132 384 947 831 553 1722 2144 384 2298 545 763 364 380 1 6 1 0 0 8 1 8 4 307 2 4 0 477 COG1372(Intein/homing endonuclease) 1741 1074 1328 1139 117 112 421 577 165 223 277 277 270 524 271 284 564 533 350 576 594 601 1029 591 619 1545 505 544 493 292 476 814 785 498 1245 1501 558 3207 521 517 328 222 8 11 6 2 3 1 3 2 4 218 4 8 1 580 COG0583(Transcriptional regulator) 15629 506 338 327 49 96 120 196 109 115 123 106 111 396 182 144 220 170 261 194 160 117 241 152 161 227 248 142 172 56 151 313 263 201 539 527 355 1997 196 217 104 89 2 0 1 0 6 0 0 0 6 83 3 1 0 153 COG0463(Glycosyltransferases involved in cell wall biogenesis) 2354 832 1008 1017 135 143 301 313 131 105 136 160 77 271 234 177 535 669 288 417 566 518 838 556 521 1392 389 514 409 176 439 679 588 458 1127 1536 719 3267 512 491 210 197 2 3 4 3 0 1 1 0 5 170 2 6 5 434 COG5295(Autotransporter adhesin) 2933 434 897 451 144 103 169 873 275 223 365 208 327 371 191 174 426 450 384 380 482 501 915 500 550 1197 687 603 445 468 332 611 759 402 791 1107 317 2239 425 477 349 259 0 2 2 6 7 4 5 1 2 196 1 5 2 481 COG2203(FOG: GAF domain) 12460 635 396 402 54 64 139 102 33 96 125 55 60 219 58 66 227 370 93 139 149 150 276 178 177 592 182 178 140 116 149 229 156 133 443 430 887 3047 224 173 53 84 6 0 0 1 0 2 0 0 2 71 0 1 2 106 COG0500(SAM-dependent methyltransferases) 2538 905 1098 1023 104 172 272 465 203 200 196 203 177 509 214 188 445 402 343 356 416 359 685 418 413 776 370 341 325 151 319 582 519 423 1180 1553 532 2918 449 477 216 217 0 2 2 2 2 1 1 4 0 169 2 4 2 265 COG0365(Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases) 2108 1051 987 1143 95 119 282 398 160 158 133 214 166 438 227 301 378 388 294 488 368 457 717 427 452 696 452 359 350 82 317 726 652 458 1370 1625 318 1856 425 438 246 239 0 0 4 2 5 2 4 6 0 210 0 4 0 371 COG0841(Cation/multidrug efflux pump) 4375 1030 968 910 102 98 282 275 138 160 176 162 117 385 176 212 293 307 315 320 302 262 541 367 323 293 360 294 261 83 259 652 544 356 1240 1206 433 2681 373 413 179 199 0 0 2 2 2 0 0 1 1 187 2 0 6 225 COG1716(FOG: FHA domain) 5393 482 516 504 44 103 162 249 113 106 124 104 123 428 182 150 363 380 254 259 282 258 483 271 327 1030 258 251 191 87 209 374 337 241 757 916 358 4748 363 317 162 159 0 4 4 4 3 1 3 2 2 110 3 1 1 220 COG0086(DNA-directed RNA polymerase, beta subunit/160 kD subunit) 1031 947 1039 1081 170 142 364 402 167 155 181 199 174 399 232 249 480 537 325 409 480 431 779 449 579 781 390 376 396 150 374 687 669 433 1125 1494 506 1738 459 430 247 196 2 0 13 2 0 1 12 2 2 241 3 2 2 374 COG0673(Predicted dehydrogenases and related proteins) 1133 904 1227 964 79 199 370 315 136 146 142 196 120 362 266 216 400 395 288 448 408 428 753 460 431 826 519 464 382 102 308 680 572 528 1488 1597 422 1655 439 527 221 260 0 0 2 0 0 1 2 6 2 220 0 0 3 330 COG2931(RTX toxins and related Ca2+-binding proteins) 3228 544 799 521 134 133 118 236 111 184 171 123 149 439 123 160 244 230 292 318 318 423 645 355 315 399 546 414 313 273 286 675 718 355 796 831 369 3878 419 529 319 280 2 7 0 6 2 4 5 2 0 164 2 0 0 414 COG1132(ABC-type multidrug transport system, ATPase and permease components) 1676 728 838 945 157 183 254 253 170 102 162 171 147 326 215 179 369 403 326 383 486 449 789 473 506 851 394 442 411 247 349 621 553 377 1149 1380 365 2167 490 437 185 203 0 2 5 4 0 6 5 1 1 173 0 3 3 378 COG0834(ABC-type amino acid transport/signal transduction systems, periplasmic component/domain) 5496 819 613 754 32 59 237 339 113 154 117 224 115 313 183 221 279 320 265 316 285 296 491 341 311 394 301 308 275 46 229 494 480 361 1065 1321 371 1442 335 398 202 196 2 0 0 2 0 3 0 0 0 160 0 2 0 351 COG0028(Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]) 1753 1048 997 1091 66 145 269 347 145 139 113 187 227 395 283 277 392 312 314 468 342 341 688 421 416 480 322 306 327 73 319 731 602 452 1274 1631 299 1176 387 489 208 206 2 2 0 0 3 5 2 4 0 215 5 5 2 306 COG0085(DNA-directed RNA polymerase, beta subunit/140 kD subunit) 932 869 942 881 111 101 346 454 200 132 147 173 155 514 246 281 486 485 276 477 397 381 722 368 456 737 428 333 343 125 287 676 563 438 1226 1534 508 1313 417 358 211 204 5 0 7 2 2 3 2 6 2 190 2 0 1 370 COG0209(Ribonucleotide reductase, alpha subunit) 858 678 725 689 74 90 248 607 206 182 296 189 268 267 226 246 432 412 356 496 421 423 856 457 460 1008 455 438 425 316 275 616 636 458 1114 1261 305 1286 413 391 252 264 0 0 5 1 7 4 1 1 2 213 3 4 4 492 COG0745(Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain) 4463 740 667 803 97 94 237 209 98 110 172 119 90 305 173 164 401 471 239 275 313 281 529 334 389 763 330 270 224 105 220 423 396 231 792 862 642 2517 320 310 144 135 2 1 1 2 2 0 3 1 2 122 0 0 6 180 COG0526(Thiol-disulfide isomerase and thioredoxins) 1999 903 990 891 120 98 270 283 166 131 119 183 109 331 216 216 349 347 243 333 350 362 719 391 380 705 310 333 329 158 273 628 482 391 1211 1291 424 1830 426 416 209 159 2 2 3 0 1 2 0 5 2 194 1 1 1 304 COG0436(Aspartate/tyrosine/aromatic aminotransferase) 1435 822 974 912 93 129 208 243 126 103 139 158 162 349 210 173 364 398 261 375 367 293 646 388 384 703 378 365 360 104 307 639 535 424 1091 1361 334 1852 374 496 207 181 0 0 4 1 4 2 3 3 0 193 0 4 0 354 COG4177(ABC-type branched-chain amino acid transport system, permease component) 3811 514 464 640 35 91 203 230 92 106 145 125 101 295 103 177 352 375 240 297 286 271 440 274 245 769 308 318 230 57 224 443 373 278 855 1103 221 3365 313 344 130 145 2 3 1 2 0 1 0 5 2 125 2 2 1 311 COG0517(FOG: CBS domain) 2727 796 874 784 67 75 240 309 125 133 176 159 113 310 201 153 328 475 242 285 290 292 514 310 368 816 309 300 265 95 223 463 412 334 870 1060 445 2291 378 343 162 123 0 1 0 0 6 2 0 3 0 142 0 1 2 248 COG0577(ABC-type antimicrobial peptide transport system, permease component) 2958 576 745 566 60 65 210 252 100 95 105 136 93 343 179 200 199 270 246 311 316 276 470 267 380 563 346 316 274 73 247 536 458 353 887 1040 376 2253 437 434 208 183 2 1 2 1 0 0 6 0 2 169 1 1 7 324 COG0508(Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes) 1382 820 800 785 89 87 263 299 154 140 113 187 108 296 214 168 347 359 301 262 261 327 532 370 319 672 324 349 291 93 221 563 513 350 1117 1149 268 2386 336 419 196 153 4 0 0 1 0 1 1 0 0 130 5 3 0 325 COG3119(Arylsulfatase A and related enzymes) 685 457 691 563 354 429 323 409 197 240 216 121 269 643 210 170 189 187 565 376 285 465 580 325 309 544 350 322 290 241 213 592 378 311 1314 1157 208 1717 319 543 194 208 0 1 4 2 4 0 0 4 0 240 0 0 0 192 COG0188(Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit) 955 772 822 791 103 103 292 339 184 111 102 178 142 297 184 204 375 410 292 394 329 283 655 339 378 657 286 342 351 116 214 591 487 372 1102 1185 392 1810 366 371 194 168 0 3 4 3 0 0 3 2 3 181 3 1 2 276 COG0069(Glutamate synthase domain 2) 1249 958 728 896 77 98 279 369 125 188 108 205 158 349 192 247 284 254 255 385 338 323 524 329 377 446 366 323 306 63 316 544 556 432 1119 1293 283 1292 444 412 204 185 1 5 4 0 0 0 0 0 2 205 4 2 0 309 COG0187(Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit) 934 775 845 765 84 82 289 295 157 136 142 153 177 306 210 261 417 398 245 435 305 325 551 303 338 729 292 293 315 65 222 512 541 333 1175 1218 325 1677 294 414 237 158 2 0 2 0 2 6 1 7 2 147 2 3 6 245 COG0587(DNA polymerase III, alpha subunit) 1081 644 787 712 70 79 200 254 115 133 117 211 103 361 165 183 366 439 221 272 279 266 560 354 342 1017 348 342 314 106 268 562 473 340 927 1111 278 2213 356 414 167 144 0 1 0 3 2 0 0 0 2 128 0 1 0 279 COG0154(Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases) 1488 843 852 852 63 124 238 253 113 141 90 120 107 476 158 173 305 260 242 379 351 337 619 347 318 625 315 281 299 61 253 526 468 333 1029 1031 201 1364 277 401 154 191 0 2 0 0 8 3 0 4 0 146 0 6 1 217 COG0784(FOG: CheY-like receiver) 8050 482 228 192 58 57 63 104 31 39 83 52 46 202 73 68 218 233 103 71 115 113 150 94 98 402 172 93 87 65 111 127 72 55 202 260 964 3307 88 93 25 63 2 0 0 0 1 4 0 0 0 49 0 1 0 51 COG1249(Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes) 1870 668 750 628 89 85 210 236 114 121 91 121 86 309 204 175 275 260 247 258 285 272 520 310 285 366 287 244 271 117 255 488 397 291 973 943 369 2199 319 386 165 141 6 4 0 2 0 2 1 5 0 124 0 2 0 278 COG0749(DNA polymerase I - 3-5 exonuclease and polymerase domains) 729 639 720 644 76 96 253 568 115 106 250 153 141 276 147 180 256 337 351 318 361 336 541 292 345 565 308 246 261 193 242 562 525 281 969 1037 288 1883 312 337 164 146 8 0 6 2 2 2 0 0 2 118 2 0 2 283 COG0006(Xaa-Pro aminopeptidase) 1001 801 860 764 59 76 229 268 131 112 115 192 94 277 201 227 232 240 186 409 286 330 490 287 279 382 298 288 306 49 213 481 524 395 1073 1677 283 1213 342 416 173 171 0 2 3 0 0 0 0 5 0 176 0 1 0 351 COG0604(NADPH:quinone reductase and related Zn-dependent oxidoreductases) 2026 778 861 733 54 94 189 260 117 123 79 145 100 367 193 198 194 212 207 316 249 275 507 271 282 392 303 310 251 64 191 461 479 377 981 1032 174 1706 251 363 163 190 0 2 0 1 0 1 0 0 0 136 2 1 0 254 COG0174(Glutamine synthetase) 1099 850 804 847 44 70 232 297 157 146 86 178 148 247 177 196 240 262 196 372 288 228 459 305 324 561 316 266 269 66 192 500 420 401 1107 1490 204 959 324 340 180 154 0 1 2 2 0 3 2 5 2 190 2 2 0 234 COG0119(Isopropylmalate/homocitrate/citramalate synthases) 1536 800 679 738 51 79 222 251 122 136 114 176 105 211 184 197 275 299 216 318 280 235 456 307 313 585 295 299 244 55 246 458 430 353 1055 1132 283 1067 339 315 202 131 6 2 1 1 1 1 4 0 0 133 0 1 0 328 COG0768(Cell division protein FtsI/penicillin-binding protein 2) 962 773 724 771 119 79 246 286 113 77 91 130 75 183 151 187 250 319 248 254 311 276 577 291 387 565 280 315 268 73 282 520 425 341 902 1341 299 1315 349 387 163 111 0 8 0 1 2 3 1 0 2 155 3 2 2 258 COG0525(Valyl-tRNA synthetase) 1157 647 733 652 86 53 211 217 92 82 82 140 101 263 167 153 290 329 197 264 333 304 504 282 270 556 254 317 250 97 232 469 397 268 819 1020 408 2235 273 328 172 136 2 2 4 2 2 3 5 0 2 135 1 2 0 245 COG0183(Acetyl-CoA acetyltransferase) 1743 659 833 668 64 82 211 199 124 144 125 138 135 472 213 183 286 249 264 299 259 292 506 298 243 584 299 264 227 63 169 475 455 283 847 1042 229 1219 295 321 151 158 2 5 5 2 0 2 0 1 4 145 0 2 0 287 COG0458(Carbamoylphosphate synthase large subunit (split gene in MJ)) 852 813 861 755 64 60 270 243 102 127 91 133 92 229 178 167 309 323 155 286 336 304 559 373 316 481 299 309 301 101 252 454 456 355 964 1143 262 1172 323 392 202 165 2 0 4 1 0 4 4 2 0 161 0 4 2 280 COG1053(Succinate dehydrogenase/fumarate reductase, flavoprotein subunit) 1291 871 787 807 69 68 234 215 129 109 79 142 109 319 164 202 274 249 191 300 283 234 499 292 314 401 289 319 319 44 255 490 449 308 902 1229 294 832 338 349 183 170 0 8 2 1 0 1 1 0 0 175 2 2 0 262 COG0410(ABC-type branched-chain amino acid transport systems, ATPase component) 2750 518 469 575 35 90 208 180 86 99 90 91 67 295 143 115 282 317 150 261 238 256 427 266 266 639 309 272 171 28 197 301 338 259 698 935 214 1876 265 302 130 137 2 0 0 5 2 1 0 1 0 114 1 2 2 253 COG0060(Isoleucyl-tRNA synthetase) 986 659 774 735 90 49 211 232 85 118 58 131 86 236 175 195 296 284 204 285 330 242 490 326 323 684 232 240 273 87 246 509 516 274 925 1120 289 1244 318 355 177 165 1 0 2 1 0 0 3 0 2 152 0 0 1 275 COG1109(Phosphomannomutase) 818 753 785 674 67 47 256 205 123 88 104 122 49 216 149 183 336 342 171 308 310 295 484 322 302 587 313 273 257 78 228 468 428 297 805 1153 252 1691 300 288 152 144 5 1 2 0 6 0 0 2 3 136 0 1 1 227 COG0568(DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)) 1098 741 707 744 66 81 208 240 136 110 71 100 113 298 180 160 196 200 222 256 318 262 536 328 347 414 246 247 310 115 281 550 390 310 883 1026 299 1470 384 254 149 148 4 2 3 0 1 3 2 0 0 130 3 4 6 207 COG0495(Leucyl-tRNA synthetase) 841 728 774 719 58 55 202 233 117 111 57 133 112 193 154 158 274 284 176 263 332 278 429 346 257 671 233 311 264 77 218 485 431 287 806 1046 353 1577 310 346 158 156 2 0 10 2 5 2 1 4 0 128 1 0 0 267 COG0446(Uncharacterized NAD(FAD)-dependent dehydrogenases) 1632 575 591 719 24 67 182 251 132 122 134 128 90 422 149 234 222 166 251 317 185 189 350 211 212 195 258 221 182 37 143 443 372 281 917 1188 247 1897 283 340 152 157 2 2 1 1 0 2 0 0 1 122 0 0 2 212 COG0411(ABC-type branched-chain amino acid transport systems, ATPase component) 2361 451 413 525 26 87 161 197 110 91 90 131 75 277 128 132 281 347 167 236 215 249 389 248 247 610 260 273 171 42 218 352 320 256 738 1026 222 1902 234 255 149 133 2 0 2 4 0 1 0 2 0 138 2 0 0 251 COG0178(Excinuclease ATPase subunit) 1011 658 691 642 91 85 247 218 116 88 96 140 81 192 153 170 303 334 217 257 278 333 502 322 338 565 251 284 256 68 240 444 384 316 947 997 263 1062 289 304 162 170 0 1 0 0 0 0 1 3 2 152 1 2 0 253 COG0277(FAD/FMN-containing dehydrogenases) 1858 513 621 621 55 86 138 219 92 79 114 115 122 308 159 167 388 252 213 254 266 198 394 225 199 519 289 229 221 65 173 429 317 274 693 846 215 2034 256 253 111 84 2 2 0 2 4 4 1 1 0 83 0 0 0 215 COG0210(Superfamily I DNA and RNA helicases) 1260 524 613 516 72 61 181 199 93 103 117 95 73 232 167 142 448 380 234 234 200 200 408 247 243 794 219 199 198 72 194 400 374 196 697 832 290 2295 250 243 113 117 2 0 0 2 0 0 1 0 0 119 3 3 1 220 COG0491(Zn-dependent hydrolases, including glyoxylases) 1251 592 762 617 68 78 221 224 111 110 81 146 81 330 170 173 244 175 230 282 297 237 493 261 249 433 300 235 207 61 190 458 359 250 812 1133 241 1418 245 337 151 164 1 2 2 3 2 3 1 2 2 126 0 1 0 234 COG0624(Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases) 1131 577 693 572 74 71 218 215 96 86 119 128 88 359 167 204 248 254 268 330 263 260 431 236 242 513 298 272 221 55 213 434 351 264 940 1050 228 1243 260 267 150 127 0 0 0 0 1 0 0 4 0 136 4 0 1 293 COG0513(Superfamily II DNA and RNA helicases) 1572 511 502 480 93 150 151 237 158 139 171 155 93 352 205 163 280 296 259 245 165 197 316 179 217 427 209 174 158 130 160 418 407 239 668 909 327 1860 278 337 164 88 0 4 0 0 0 2 0 0 2 114 0 0 0 194 COG2303(Choline dehydrogenase and related flavoproteins) 1457 679 593 666 44 96 197 255 119 86 89 114 97 349 151 198 228 222 240 222 219 244 414 283 314 284 245 278 251 68 192 503 416 361 948 1025 155 836 311 351 141 183 2 2 5 0 1 3 0 3 0 115 1 4 4 203 COG1250(3-hydroxyacyl-CoA dehydrogenase) 1816 586 724 591 45 76 161 228 103 110 106 111 99 350 155 154 200 171 233 286 237 245 483 243 286 384 236 230 223 56 180 420 343 252 729 975 166 1213 221 333 165 164 0 0 1 0 0 4 0 2 2 127 0 0 0 226 COG3920(Signal transduction histidine kinase) 5526 420 382 295 48 50 93 91 26 55 70 37 55 151 57 66 231 344 99 117 104 118 214 122 133 699 148 78 60 51 87 130 114 52 209 286 562 2654 116 67 31 32 6 0 2 0 1 2 0 0 0 21 0 0 0 53 COG0845(Membrane-fusion protein) 3361 558 546 459 60 66 133 132 82 84 94 70 72 229 108 111 202 160 196 150 201 154 333 194 210 224 204 206 149 81 199 363 281 230 628 532 286 1974 249 216 95 90 0 2 0 1 1 0 0 1 0 98 2 0 8 114 COG0480(Translation elongation factors (GTPases)) 805 619 728 609 77 68 191 183 88 107 83 98 101 249 126 141 284 314 185 255 244 245 478 295 315 512 217 260 222 75 211 394 354 281 723 894 316 1621 250 244 145 153 2 0 0 0 1 0 0 2 2 135 2 2 2 224 COG0415(Deoxyribodipyrimidine photolyase) 684 499 532 546 72 123 208 223 93 111 108 124 101 219 116 147 183 189 174 277 251 234 602 331 358 355 236 318 302 121 264 471 464 340 903 510 164 1372 345 352 199 149 5 2 2 5 3 1 3 8 0 148 3 1 0 292 COG0524(Sugar kinases, ribokinase family) 1293 531 590 574 56 89 184 187 78 75 58 118 89 290 123 118 242 250 174 181 275 192 428 292 259 494 251 267 221 77 232 408 351 323 850 905 238 1257 272 293 111 162 1 1 0 0 1 0 1 1 2 125 2 1 2 207 COG0664(cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases) 2365 364 451 356 63 99 130 171 51 59 127 71 56 305 109 107 266 271 171 188 208 197 302 173 225 583 232 189 147 109 149 339 264 200 508 608 292 2216 292 293 86 90 0 0 4 0 0 0 3 1 0 65 1 0 5 185 COG0067(Glutamate synthase domain 1) 1101 677 539 631 49 56 209 307 85 138 61 193 116 294 181 201 200 218 191 269 234 222 360 242 257 305 225 232 204 28 195 380 393 291 866 1005 223 1164 269 258 141 126 0 1 1 0 2 2 0 0 2 155 4 3 0 198 COG0111(Phosphoglycerate dehydrogenase and related dehydrogenases) 936 608 712 654 67 80 211 179 86 80 97 115 75 267 153 145 248 285 194 273 226 248 423 228 251 481 232 227 207 69 192 414 362 282 792 932 251 1218 243 289 114 124 0 0 0 2 1 0 1 3 2 132 1 0 0 175 COG0443(Molecular chaperone) 1004 568 586 604 78 77 195 207 128 105 69 102 112 232 138 178 232 240 164 272 336 291 514 280 328 444 180 274 265 111 239 408 329 256 794 852 242 912 341 265 125 132 2 5 0 1 3 0 3 4 4 143 0 4 0 193 COG0399(Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis) 672 483 715 614 55 80 165 239 92 94 110 126 81 171 141 127 215 281 190 269 247 256 478 270 305 662 276 273 214 88 251 401 332 318 819 1070 297 802 265 302 157 131 2 3 0 3 0 1 0 1 0 106 3 0 0 232 COG0494(NTP pyrophosphohydrolases including oxidative damage repair enzymes) 1225 566 698 565 50 60 163 176 94 90 85 102 81 234 118 130 227 239 192 234 233 187 451 245 285 496 226 210 212 69 173 352 296 223 600 759 251 1780 238 247 127 86 0 1 6 2 0 1 1 1 0 134 1 0 0 179 COG0739(Membrane proteins related to metalloendopeptidases) 1039 538 540 543 69 54 163 229 147 120 129 170 88 249 107 138 205 167 157 231 167 237 360 221 231 326 207 234 199 52 175 421 420 319 839 809 243 1480 269 339 146 156 2 3 2 0 1 1 0 1 0 108 3 0 0 213 COG0247(Fe-S oxidoreductase) 1775 367 485 357 31 48 165 209 64 83 83 93 92 255 137 196 297 277 174 258 182 221 351 191 199 533 272 236 198 29 131 336 295 179 555 665 197 1979 222 244 172 78 4 0 0 1 0 1 0 0 0 64 1 2 0 244 COG0532(Translation initiation factor 2 (IF-2; GTPase)) 792 576 571 558 74 48 210 198 104 117 69 104 80 159 131 111 270 251 158 208 274 245 432 242 267 491 261 252 221 84 187 391 357 216 799 803 235 1512 246 259 122 155 0 0 0 2 0 2 0 0 0 169 5 2 2 159 COG0625(Glutathione S-transferase) 2055 643 659 578 83 101 192 267 102 139 91 100 121 379 147 108 142 99 221 212 225 177 401 230 244 125 225 202 190 87 170 372 318 233 749 744 161 919 235 251 77 123 1 2 1 0 1 1 2 1 0 100 2 1 0 139 COG0258(5-3 exonuclease (including N-terminal domain of PolI)) 728 501 600 435 66 60 164 399 59 105 155 120 86 264 120 131 211 272 160 242 232 226 414 230 253 572 226 197 237 148 165 420 345 256 683 838 208 1408 250 260 127 83 2 0 6 4 0 1 2 0 4 68 2 0 4 197 COG0654(2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases) 2081 593 589 545 66 77 174 242 108 80 75 119 76 259 100 112 182 165 112 207 226 192 380 250 229 248 217 208 227 46 156 385 304 255 736 825 215 855 238 258 81 124 1 0 0 1 0 1 4 1 0 97 1 0 0 178 COG0004(Ammonia permease) 1304 624 549 651 56 59 147 252 86 133 78 106 111 335 186 156 187 175 163 283 231 233 399 242 266 281 240 284 286 59 221 346 362 243 782 839 227 626 216 274 134 110 0 0 0 5 0 5 2 0 0 133 2 0 3 193 COG2030(Acyl dehydratase) 2377 483 598 469 33 59 136 250 95 80 94 96 78 242 92 115 157 125 155 194 206 188 370 189 227 222 213 178 167 26 137 351 297 197 687 759 110 1437 217 246 120 138 0 3 1 0 0 2 3 1 0 107 2 0 0 156 COG0542(ATPases with chaperone activity, ATP-binding subunit) 1040 303 403 400 53 93 117 117 62 97 95 79 78 264 90 83 299 292 215 148 280 168 454 228 284 720 228 199 217 169 192 410 281 210 514 510 283 2076 299 253 87 103 2 0 2 3 2 2 0 0 0 143 2 2 0 161 COG1131(ABC-type multidrug transport system, ATPase component) 1359 468 740 467 52 92 151 171 80 89 82 101 56 197 139 108 286 296 163 215 200 234 370 225 224 622 223 180 184 95 170 316 276 231 525 732 218 1583 155 221 116 96 3 3 1 1 0 0 0 2 0 108 1 2 2 180 COG0653(Preprotein translocase subunit SecA (ATPase, RNA helicase)) 591 607 630 630 62 83 183 208 95 79 91 114 51 178 113 141 246 232 152 207 214 215 394 263 236 417 247 253 223 73 222 373 380 242 817 822 251 1174 259 292 133 139 0 1 2 0 0 4 2 1 6 147 2 1 0 194 COG1196(Chromosome segregation ATPases) 697 501 611 567 47 85 145 239 89 85 94 112 60 161 131 104 234 226 193 204 285 252 419 236 282 444 222 215 223 117 180 401 334 238 723 806 202 1319 275 259 180 107 0 0 0 3 0 0 0 0 2 123 4 1 0 204 COG0115(Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase) 877 527 634 595 56 46 164 190 99 77 87 117 94 207 125 107 189 152 180 195 253 207 422 234 257 390 220 241 210 85 176 461 336 247 795 952 145 948 262 258 132 132 0 1 4 0 2 3 0 3 0 134 1 0 0 184 COG0439(Biotin carboxylase) 1160 533 588 515 67 62 226 189 80 84 77 119 68 224 141 185 152 118 156 189 280 182 438 246 223 245 202 215 212 73 187 355 298 242 592 745 204 1381 205 219 130 115 0 0 0 0 2 1 0 0 0 125 0 4 2 149 COG0129(Dihydroxyacid dehydratase/phosphogluconate dehydratase) 983 501 502 491 42 77 207 181 84 112 114 131 91 308 145 151 241 220 168 221 221 172 384 241 233 414 248 217 180 53 182 371 317 221 777 804 186 940 218 250 136 118 1 6 0 2 2 2 0 3 0 116 0 1 0 189 COG0539(Ribosomal protein S1) 792 550 590 554 47 59 198 193 83 86 60 105 73 176 90 146 187 238 120 209 228 210 399 239 251 478 208 207 203 59 226 333 346 267 777 772 165 1198 222 259 118 99 0 0 1 0 2 0 2 0 0 108 0 5 0 188 COG0013(Alanyl-tRNA synthetase) 721 586 624 584 64 59 229 195 99 77 68 113 69 150 115 159 179 213 153 214 210 225 406 281 271 367 154 188 242 78 190 383 357 249 698 902 219 1031 230 228 170 80 1 0 2 0 0 1 6 1 2 105 0 3 4 170 COG1804(Predicted acyl-CoA transferases/carnitine dehydratase) 1601 471 710 615 72 88 170 207 86 106 70 79 101 386 119 103 206 136 245 238 229 272 504 256 236 352 192 132 191 30 154 298 286 195 555 620 94 783 190 195 87 118 0 0 0 0 0 1 0 4 0 112 4 2 2 153 COG0465(ATP-dependent Zn proteases) 819 527 496 536 59 61 175 185 92 58 72 85 124 145 99 131 192 212 142 258 331 231 475 278 317 511 144 218 249 140 207 369 249 185 646 737 247 960 329 228 93 113 0 3 1 1 3 0 3 0 0 104 0 0 2 171 COG1653(ABC-type sugar transport system, periplasmic component) 1010 572 502 572 27 64 265 141 55 81 65 83 87 250 87 110 158 243 159 280 240 205 358 258 300 301 305 206 189 14 202 317 321 301 738 692 210 874 324 201 141 113 0 2 1 7 0 1 0 0 2 133 0 1 0 239 COG0459(Chaperonin GroEL (HSP60 family)) 612 467 551 455 61 74 146 208 62 119 136 82 82 306 134 144 225 298 178 250 231 217 461 266 231 602 214 261 225 107 170 353 390 253 595 775 197 743 230 242 132 123 3 4 0 2 2 2 1 2 2 128 0 2 1 223 COG0070(Glutamate synthase domain 3) 1089 578 453 592 48 56 208 302 96 98 58 111 107 243 153 166 186 145 149 230 168 203 308 192 255 242 189 205 175 49 181 318 319 270 676 855 168 1094 263 255 89 117 1 4 3 0 4 0 0 0 0 122 1 2 0 179 COG0265(Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain) 813 507 596 516 60 84 154 164 107 105 40 91 66 223 101 138 249 241 186 200 242 218 419 226 227 380 227 234 185 69 162 324 254 199 650 693 184 1545 203 244 112 64 0 3 1 1 0 0 0 1 0 110 2 2 2 148 COG2141(Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases) 2507 377 592 489 26 32 84 121 83 50 44 97 58 345 136 176 161 178 247 243 218 217 360 169 201 628 205 159 148 14 94 254 238 204 376 942 111 482 192 181 110 107 2 2 0 0 0 0 2 0 0 89 0 0 0 189 COG3842(ABC-type spermidine/putrescine transport systems, ATPase components) 1352 491 461 505 11 50 153 151 75 67 54 85 51 154 98 123 164 230 161 245 194 191 337 174 212 457 202 181 172 26 187 399 323 243 695 903 158 1060 255 310 125 103 1 0 2 1 0 2 2 2 2 105 1 0 0 176 COG1404(Subtilisin-like serine proteases) 3219 233 536 161 52 40 47 76 57 94 57 53 56 176 81 70 92 89 89 174 188 274 367 146 152 480 139 152 129 116 86 389 444 135 215 389 211 1274 167 278 213 152 6 0 0 0 0 1 2 2 3 97 0 1 0 211 COG0516(IMP dehydrogenase/GMP reductase) 656 500 564 517 41 45 132 175 84 91 100 99 71 146 134 103 251 289 197 201 194 201 420 205 245 635 187 199 190 77 142 282 287 205 578 726 177 1487 219 228 106 89 5 0 0 2 1 0 1 3 0 78 0 2 2 143 COG2204(Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains) 1932 391 404 382 72 77 119 144 92 87 123 69 52 257 94 66 135 127 141 133 146 165 282 166 174 288 200 162 172 47 130 290 313 187 631 688 344 1442 194 312 88 101 0 1 1 0 2 3 1 2 0 87 2 0 0 169 COG0556(Helicase subunit of the DNA excision repair complex) 660 505 493 497 54 62 171 157 53 49 65 118 89 151 105 70 179 234 159 236 192 215 342 233 231 439 192 213 182 66 183 384 342 219 602 722 219 1466 206 284 134 126 0 1 0 2 0 0 3 0 0 153 2 0 0 207 COG0481(Membrane GTPase LepA) 693 488 535 534 58 45 174 182 59 100 90 68 77 160 106 135 180 231 166 246 240 180 368 236 274 317 229 190 207 58 191 346 306 229 785 796 184 1199 236 248 119 88 2 2 4 2 0 0 0 0 4 98 2 0 2 192 COG0044(Dihydroorotase and related cyclic amidohydrolases) 682 570 557 559 60 60 198 125 46 58 72 102 36 158 151 155 192 221 150 195 224 234 333 240 270 429 159 229 170 51 165 361 333 254 727 920 204 997 221 260 140 105 0 0 0 1 3 0 1 2 2 117 4 5 0 146 COG0843(Heme/copper-type cytochrome/quinol oxidases, subunit 1) 928 569 569 547 51 53 195 161 59 64 66 121 98 179 126 105 204 206 130 254 201 230 363 251 227 383 233 186 204 54 152 381 327 255 732 746 130 841 231 231 144 134 0 2 3 0 0 2 0 2 0 128 5 2 0 185 COG1894(NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit) 715 560 491 555 28 49 176 200 60 79 46 120 77 192 144 200 225 247 146 276 209 194 310 223 187 428 225 224 182 17 160 318 303 258 735 929 202 991 211 219 117 102 5 0 0 1 6 0 0 0 2 81 1 0 0 216 COG0772(Bacterial cell division membrane protein) 688 475 547 534 66 58 192 157 78 53 64 113 41 130 121 130 200 196 151 194 221 197 378 206 300 390 212 211 178 54 212 345 339 235 761 841 217 1113 241 244 132 123 0 0 0 2 3 2 0 0 0 96 1 1 0 178 COG0330(Membrane protease subunits, stomatin/prohibitin homologs) 970 560 595 574 55 52 209 173 77 115 91 88 89 234 109 108 140 187 150 237 226 185 400 245 235 151 207 225 223 66 145 347 339 205 823 751 252 815 214 215 108 93 1 0 3 2 1 0 3 3 0 149 1 3 0 164 COG0683(ABC-type branched-chain amino acid transport systems, periplasmic component) 1608 442 347 499 29 74 152 135 76 58 51 90 60 253 98 126 215 230 123 226 255 158 339 192 184 343 217 186 166 33 165 303 261 193 579 761 237 1171 184 213 102 122 0 0 2 0 0 3 3 0 0 94 2 2 5 207 COG1022(Long-chain acyl-CoA synthetases (AMP-forming)) 1194 431 545 497 49 77 135 174 60 75 74 98 61 175 104 138 154 170 117 239 187 219 343 222 275 283 241 233 175 67 212 312 295 217 600 757 115 1152 213 237 147 109 1 0 0 4 2 2 1 0 0 102 2 3 0 207 COG0730(Predicted permeases) 937 472 418 479 33 70 163 218 92 93 68 121 82 213 123 152 225 273 159 194 211 189 321 219 233 349 241 234 173 43 205 343 307 242 672 784 200 1014 204 224 125 120 0 1 2 1 0 0 0 0 0 92 0 0 0 166 COG1538(Outer membrane protein) 3847 396 418 336 46 33 117 114 36 57 67 72 73 158 69 89 142 161 126 135 128 144 224 168 176 172 134 134 167 37 118 262 246 148 535 472 167 810 159 209 79 67 0 2 1 2 2 1 0 0 0 63 1 2 0 93 COG0142(Geranylgeranyl pyrophosphate synthase) 510 507 535 546 71 58 139 153 80 104 78 108 53 200 154 104 218 219 176 232 182 204 397 206 248 417 174 226 192 87 180 349 319 194 736 750 142 1049 229 227 115 156 0 1 0 1 3 0 2 1 2 116 0 2 0 171 COG0304(3-oxoacyl-(acyl-carrier-protein) synthase) 1248 482 488 503 51 66 183 129 70 105 67 72 100 253 124 105 143 111 145 206 172 160 320 246 212 214 209 187 169 66 141 372 332 203 693 705 163 1064 255 206 117 116 3 1 1 0 0 0 0 0 1 127 0 1 4 165 COG0515(Serine/threonine protein kinase) 1191 273 567 416 296 325 74 91 66 54 39 44 53 194 62 72 247 268 242 155 168 190 282 119 163 592 142 160 105 382 111 188 154 114 318 465 268 1974 145 148 71 63 0 2 0 0 0 4 0 0 0 78 1 0 0 126 COG0493(NADPH-dependent glutamate synthase beta chain and related oxidoreductases) 1301 516 540 512 44 40 145 195 63 64 69 98 77 224 116 160 211 295 174 222 148 177 299 180 172 447 195 221 149 24 133 258 243 206 552 732 172 1049 156 191 105 99 2 0 0 0 3 1 0 0 2 78 0 0 0 145 COG0719(ABC-type transport system involved in Fe-S cluster assembly, permease component) 394 414 552 554 68 54 172 145 88 65 55 87 55 102 127 98 222 257 116 242 231 239 386 250 215 372 193 241 222 66 217 356 326 257 728 803 192 910 227 282 134 124 5 2 2 0 4 0 0 4 2 119 0 1 3 223 COG1185(Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)) 567 595 498 533 54 57 212 178 80 108 60 89 81 144 121 106 192 198 146 198 158 205 355 230 235 359 207 208 199 50 187 356 341 242 727 824 159 861 232 265 97 109 0 5 2 0 0 7 0 1 0 112 5 4 0 190 COG0621(2-methylthioadenine synthetase) 624 462 587 501 84 68 154 144 69 60 68 82 61 137 74 111 237 219 140 145 206 204 399 209 253 414 216 219 269 64 194 293 274 225 675 795 213 985 227 241 84 112 0 0 0 1 0 0 0 2 0 88 2 2 2 148 COG3839(ABC-type sugar transport systems, ATPase components) 951 431 334 472 28 76 208 124 79 59 75 108 52 204 116 140 145 155 170 256 179 173 318 232 216 235 322 181 160 29 156 332 312 237 717 625 184 1004 302 235 148 114 0 2 1 0 0 0 2 0 4 130 0 2 2 246 COG2084(3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases) 1038 494 459 536 36 82 137 251 89 124 70 103 80 220 118 122 153 148 152 223 158 198 318 182 168 239 193 167 117 30 118 305 296 246 755 800 145 865 230 262 97 137 4 4 1 0 0 6 0 3 0 104 8 2 0 181 COG0046(Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain) 618 571 594 516 41 55 173 142 76 74 65 93 82 176 130 124 190 182 107 198 193 206 375 251 283 160 184 212 189 78 199 368 267 239 659 751 173 938 213 268 115 120 2 0 4 0 0 2 5 0 2 121 0 3 2 177 COG1136(ABC-type antimicrobial peptide transport system, ATPase component) 1240 430 570 402 52 61 130 102 92 53 64 88 55 173 106 101 113 107 126 196 231 217 387 229 243 248 179 232 152 58 135 308 302 191 461 635 239 1219 198 233 139 123 2 2 0 0 3 0 0 2 0 87 0 4 2 192 COG0492(Thioredoxin reductase) 626 613 541 552 54 65 176 168 54 40 51 90 67 146 150 112 183 155 126 193 241 214 344 256 214 279 170 235 197 66 182 355 311 238 748 830 195 733 204 208 96 99 0 1 2 0 0 0 2 2 2 126 1 2 2 161 COG0567(2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes) 594 616 411 522 39 57 188 161 90 91 73 108 60 177 127 103 201 232 138 200 146 194 305 195 212 377 154 165 182 37 167 364 320 215 764 818 205 908 211 227 97 114 2 1 0 0 1 0 0 0 0 106 0 2 0 188 COG0505(Carbamoylphosphate synthase small subunit) 655 531 538 448 59 49 199 185 74 62 61 99 57 131 103 128 203 196 102 181 184 166 367 202 202 381 239 208 167 60 127 382 299 240 670 695 177 998 258 267 127 121 2 0 2 0 0 2 1 2 0 99 0 2 6 147 COG0072(Phenylalanyl-tRNA synthetase beta subunit) 543 495 537 543 50 43 154 194 63 70 74 104 51 104 119 81 209 213 119 212 231 178 407 221 270 408 168 175 170 44 156 351 319 224 688 808 218 822 220 268 144 105 0 1 2 0 0 0 2 3 0 90 0 0 0 164 COG1173(ABC-type dipeptide/oligopeptide/nickel transport systems, permease components) 1271 387 474 433 33 92 113 134 73 52 63 70 68 231 91 83 143 174 191 160 178 191 348 188 194 445 215 211 121 50 141 314 220 227 595 679 173 1140 163 248 86 98 0 3 0 2 0 0 2 0 0 85 1 0 1 167 COG0008(Glutamyl- and glutaminyl-tRNA synthetases) 551 391 559 440 68 57 153 163 72 75 77 56 70 254 108 93 193 205 140 157 224 193 366 185 197 407 168 187 176 73 152 351 275 167 658 777 211 1189 241 239 117 132 2 1 1 0 0 0 0 7 2 92 0 0 0 147 COG0021(Transketolase) 875 547 533 531 39 40 167 165 49 108 69 82 55 157 86 122 190 204 123 185 203 174 333 219 191 416 172 179 172 57 128 315 275 198 555 698 186 1172 168 180 75 99 0 3 1 0 0 0 6 0 0 100 0 0 0 166 COG0667(Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)) 1092 431 616 470 45 74 152 167 87 101 60 91 87 211 101 111 198 247 159 205 163 176 345 179 199 364 164 201 166 45 158 267 253 193 621 717 168 853 162 210 82 78 0 0 2 2 0 4 2 0 0 97 1 2 3 148 COG1233(Phytoene dehydrogenase and related proteins) 363 354 532 422 65 62 100 137 90 66 67 98 61 163 107 82 213 254 171 153 216 178 325 199 202 630 131 168 203 110 147 375 299 172 571 507 104 1494 240 287 95 101 0 0 2 0 2 4 1 3 0 119 5 3 1 162 COG4664(TRAP-type mannitol/chloroaromatic compound transport system, large permease component) 419 552 472 603 25 43 134 215 78 104 56 88 105 195 102 151 165 243 155 255 188 224 327 198 176 123 240 224 167 14 128 407 386 266 781 917 168 406 254 257 121 150 2 4 0 6 3 0 2 0 0 89 5 0 0 158 COG0147(Anthranilate/para-aminobenzoate synthases component I) 688 428 443 509 43 43 143 169 91 86 66 95 59 144 97 114 191 175 133 166 194 176 340 215 216 474 170 169 164 70 168 333 274 201 617 723 131 1091 204 222 86 103 2 1 0 2 0 0 0 2 2 79 1 1 0 166 COG0559(Branched-chain amino acid ABC-type transport system, permease components) 1063 450 300 468 15 69 146 167 65 73 52 79 60 160 88 123 203 211 157 202 223 165 339 179 188 373 173 184 175 36 155 275 255 197 559 690 156 1058 177 192 108 103 0 2 0 2 0 0 1 2 2 111 0 4 0 230 COG2199(FOG: GGDEF domain) 6178 336 143 104 15 26 34 39 19 22 69 24 15 152 35 29 72 65 78 36 54 55 121 61 71 198 82 35 68 46 59 54 30 24 104 86 340 1266 44 28 13 25 0 3 0 1 0 0 0 0 0 37 0 2 0 30 COG0564(Pseudouridylate synthases, 23S RNA-specific) 709 476 463 471 79 57 168 153 71 79 62 89 36 196 106 129 169 179 153 155 179 190 297 202 218 250 189 184 170 61 148 325 275 199 692 716 256 959 227 236 97 103 0 1 0 0 0 1 1 0 2 79 2 2 1 165 COG0714(MoxR-like ATPases) 623 390 493 389 46 54 146 221 77 77 98 88 65 192 107 100 130 118 169 202 232 212 401 191 231 338 202 211 211 147 134 320 277 202 621 661 162 848 183 227 125 139 0 3 1 0 0 2 4 1 0 101 0 0 0 236 COG1175(ABC-type sugar transport systems, permease components) 864 488 440 490 23 72 204 111 46 48 55 66 65 148 63 102 155 204 138 229 186 168 335 206 220 385 274 223 182 13 166 294 261 257 645 584 149 646 257 221 135 101 0 2 0 0 4 0 0 0 0 109 0 0 4 250 COG0441(Threonyl-tRNA synthetase) 632 543 503 498 49 46 149 135 66 96 77 77 57 136 94 87 151 211 123 187 189 180 313 177 237 403 197 215 174 61 164 309 246 210 574 656 264 861 207 220 108 105 2 0 1 0 0 0 0 1 4 98 0 0 0 172 COG0322(Nuclease subunit of the excinuclease complex) 527 420 485 467 48 56 149 156 77 77 73 80 58 141 88 84 193 228 117 156 205 205 309 179 178 472 214 236 194 57 175 315 271 260 623 698 153 905 237 211 101 79 0 2 1 0 0 0 1 0 0 85 0 0 0 199 COG0550(Topoisomerase IA) 710 442 458 436 43 49 152 157 87 76 40 110 65 116 150 111 250 194 150 219 214 192 373 236 212 395 179 178 199 55 169 264 235 200 593 700 183 823 202 180 93 100 2 0 0 2 2 0 2 0 0 76 1 5 2 154 COG3321(Polyketide synthase modules and related proteins) 7207 129 232 132 167 144 2 13 4 9 1 14 8 54 10 16 23 57 38 27 42 51 76 58 39 142 54 65 29 114 36 69 64 46 40 113 101 530 32 46 57 29 2 0 0 0 0 1 0 2 0 16 2 0 0 86 COG0204(1-acyl-sn-glycerol-3-phosphate acyltransferase) 829 438 556 411 41 37 148 120 68 57 61 74 62 218 89 92 189 153 145 168 192 177 296 186 176 391 177 195 146 67 157 263 267 170 516 667 142 1246 217 195 93 125 0 0 2 2 0 1 3 1 0 66 0 0 2 133 COG0143(Methionyl-tRNA synthetase) 611 410 572 425 51 39 127 130 66 72 48 54 46 169 96 95 209 184 117 160 217 170 292 194 214 403 173 175 181 49 135 293 304 220 531 724 214 1133 168 235 105 113 0 0 2 3 0 0 0 0 0 71 1 0 0 180 COG0073(EMAP domain) 634 445 529 465 58 41 141 167 53 71 74 85 49 146 102 79 138 172 121 187 213 185 338 187 171 321 189 180 165 27 141 333 249 200 621 656 208 1091 213 235 102 80 0 0 0 0 0 1 1 3 0 89 0 1 1 151 COG0454(Histone acetyltransferase HPA2 and related acetyltransferases) 2576 320 357 326 39 50 97 118 77 65 82 90 24 135 115 84 169 174 94 135 162 140 215 159 155 299 124 118 116 51 106 214 201 124 465 500 146 1096 147 149 71 58 0 0 0 0 0 0 0 0 2 49 0 0 2 83 COG0518(GMP synthase - Glutamine amidotransferase domain) 557 469 499 480 39 35 118 202 77 80 48 79 44 153 119 81 171 158 127 201 193 166 275 165 220 303 186 211 191 45 143 293 299 222 646 801 179 775 230 254 124 95 1 0 0 6 0 0 2 10 2 103 0 0 0 176 COG0840(Methyl-accepting chemotaxis protein) 5905 360 154 133 15 14 13 56 25 23 31 46 10 83 46 23 61 81 32 42 47 84 129 60 79 118 129 53 86 23 73 65 52 46 115 156 410 961 30 54 10 28 2 0 0 0 0 2 0 2 0 22 0 0 2 53 COG0626(Cystathionine beta-lyases/cystathionine gamma-synthases) 941 359 387 385 41 48 132 149 55 80 51 110 53 189 125 130 153 141 142 172 205 189 286 215 229 254 183 224 162 45 138 322 247 201 560 607 116 962 241 243 92 104 0 0 1 3 2 0 2 0 4 112 2 2 0 177 COG0395(ABC-type sugar transport system, permease component) 893 493 435 536 25 73 187 87 44 43 36 81 58 165 49 100 165 208 124 222 159 139 310 223 212 307 240 174 128 18 146 277 254 253 664 663 147 680 215 189 120 121 0 1 1 0 1 0 0 0 0 111 0 0 1 182 COG0484(DnaJ-class molecular chaperone with C-terminal Zn finger domain) 475 443 453 435 48 78 101 155 68 94 68 77 90 176 90 111 225 237 134 206 185 176 365 191 209 508 157 155 203 98 170 297 241 198 538 619 166 893 181 217 104 77 0 4 0 3 2 0 0 0 2 102 0 0 0 131 COG1033(Predicted exporters of the RND superfamily) 704 489 648 511 42 32 174 137 83 57 46 115 78 140 98 90 91 107 140 227 203 267 429 215 161 93 190 223 177 42 149 331 348 230 514 745 127 385 162 256 154 153 3 1 0 1 2 0 0 0 0 84 1 0 4 289 COG1674(DNA segregation ATPase FtsK/SpoIIIE and related proteins) 919 440 368 412 50 39 149 147 60 54 67 58 87 160 127 91 188 173 137 157 176 165 268 149 146 404 171 187 164 26 127 288 284 217 591 659 182 1005 148 222 100 107 0 0 2 0 6 0 0 3 3 89 0 0 0 152 COG1593(TRAP-type C4-dicarboxylate transport system, large permease component) 509 443 460 514 31 61 168 171 98 105 87 99 101 218 98 120 168 199 192 175 164 167 309 171 206 199 149 192 160 17 155 249 264 223 652 649 219 858 191 243 87 87 0 1 0 6 0 1 2 2 2 109 0 0 0 155 COG0593(ATPase involved in DNA replication initiation) 602 466 512 457 39 48 172 118 77 58 66 100 50 140 114 77 193 192 144 160 197 189 318 208 228 344 179 158 163 29 149 325 290 258 650 740 155 693 175 187 82 117 3 3 2 0 0 2 0 0 0 72 1 1 0 145 COG2114(Adenylate cyclase, family 3 (some proteins contain HAMP domain)) 1981 331 523 419 60 106 113 144 31 62 87 43 63 185 88 59 81 87 115 169 165 209 359 204 217 183 223 184 124 87 119 250 185 121 421 358 178 788 174 182 71 77 0 0 2 0 0 3 1 2 0 76 1 1 0 101 COG0243(Anaerobic dehydrogenases, typically selenocysteine-containing) 2140 307 458 364 44 46 74 131 51 47 59 63 70 197 71 98 159 135 159 170 158 177 248 168 136 330 177 127 114 28 91 207 171 109 348 445 124 1126 139 207 67 68 0 3 0 0 0 0 0 2 0 55 0 0 1 126 COG0317(Guanosine polyphosphate pyrophosphohydrolases/synthetases) 682 427 511 446 55 48 115 146 72 66 62 86 44 107 108 104 196 200 91 156 173 171 310 195 202 304 186 158 128 53 149 255 264 192 587 634 194 1091 194 247 113 67 0 0 0 4 2 0 0 2 2 51 0 0 0 143 COG1680(Beta-lactamase class C and other penicillin binding proteins) 668 515 780 488 84 44 143 138 108 77 84 70 61 272 110 89 117 114 186 199 170 190 338 209 206 270 160 179 161 60 131 313 240 187 693 650 82 418 181 209 96 109 0 0 0 2 0 0 1 0 2 79 0 0 0 97 COG3288(NAD/NADP transhydrogenase alpha subunit) 585 499 494 465 22 44 129 140 57 90 38 94 74 193 111 114 136 160 81 193 202 181 324 192 228 287 154 190 203 55 171 299 279 228 555 681 133 745 236 227 108 101 0 0 3 0 0 0 3 3 0 90 1 2 0 177 COG0449(Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains) 641 464 482 437 48 45 134 154 89 93 47 86 46 140 100 102 203 204 135 188 205 145 329 190 234 307 140 174 164 46 179 306 284 187 535 729 197 726 156 206 112 94 0 2 0 0 0 3 2 0 0 101 0 2 4 162 COG4638(Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit) 1532 424 670 477 39 47 78 170 94 83 32 104 94 231 109 100 118 88 169 218 191 170 254 122 168 197 140 125 103 57 75 242 177 154 455 882 140 529 158 198 78 60 0 0 0 0 5 1 0 2 0 53 0 0 0 132 COG0466(ATP-dependent Lon protease, bacterial type) 606 478 506 454 53 54 178 160 83 75 62 86 66 207 117 101 161 166 133 186 168 162 360 221 219 188 196 197 146 34 140 300 269 206 647 754 197 538 182 195 114 110 1 0 2 0 3 0 0 1 1 102 0 0 0 127 COG5001(Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain) 4268 349 171 214 34 39 57 62 23 18 48 41 25 142 33 49 138 163 47 80 101 80 136 75 106 264 148 59 79 60 88 82 75 43 214 206 366 1168 74 92 35 26 2 1 0 0 0 0 0 2 2 33 0 0 2 44 COG1048(Aconitase A) 642 482 474 491 33 34 174 155 78 44 53 69 48 125 81 145 183 178 169 199 154 177 321 176 157 380 178 161 170 19 138 309 307 193 521 698 165 771 163 162 115 92 0 0 1 0 2 0 0 0 2 83 0 0 0 176 COG4948(L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily) 939 432 568 457 52 87 115 137 61 101 32 76 57 245 92 108 214 212 135 164 206 162 403 160 166 321 182 121 117 39 126 254 189 154 476 493 132 790 170 285 59 97 2 0 0 3 5 0 0 1 0 91 0 1 0 148 COG0574(Phosphoenolpyruvate synthase/pyruvate phosphate dikinase) 600 438 451 448 19 46 140 102 54 44 53 73 56 166 101 127 185 191 119 199 200 171 340 221 207 249 186 183 179 15 166 246 303 166 519 655 280 831 157 186 99 119 2 4 0 0 0 3 3 3 0 89 4 0 1 167 COG0600(ABC-type nitrate/sulfonate/bicarbonate transport system, permease component) 1834 278 258 295 34 62 89 164 47 50 65 97 48 173 90 100 160 148 118 127 97 126 196 116 128 387 199 121 82 19 80 217 178 129 360 535 107 1623 112 141 70 70 0 1 0 0 0 2 0 1 2 58 0 0 1 158 COG0065(3-isopropylmalate dehydratase large subunit) 619 482 473 502 48 42 152 129 70 77 69 92 90 227 110 121 175 152 124 189 139 141 293 169 210 254 190 199 150 63 128 285 285 218 551 621 126 767 187 207 92 100 0 2 3 3 2 3 0 1 2 87 0 1 4 123 COG0272(NAD-dependent DNA ligase (contains BRCT domain type II)) 487 346 468 416 42 45 151 140 69 73 40 91 47 159 97 110 178 200 137 172 201 171 304 201 182 336 174 163 184 47 194 286 245 204 496 699 179 857 218 209 108 74 2 0 1 2 2 0 1 1 0 103 4 4 0 196 COG0161(Adenosylmethionine-8-amino-7-oxononanoate aminotransferase) 1119 372 442 446 25 70 125 173 62 74 73 74 96 234 101 93 108 107 155 130 149 155 277 174 167 194 122 134 160 34 123 319 250 212 623 666 107 680 224 213 77 87 2 1 0 4 1 1 0 0 0 83 0 2 0 145 COG0445(NAD/FAD-utilizing enzyme apparently involved in cell division) 500 571 529 496 56 52 147 157 67 92 48 95 67 235 116 81 144 81 124 209 205 175 349 205 182 135 161 192 162 66 154 325 323 150 652 750 150 410 170 235 104 90 0 3 1 1 0 0 0 1 1 96 0 0 1 144 COG0765(ABC-type amino acid transport system, permease component) 1434 372 325 413 16 37 112 143 47 53 60 103 42 135 97 96 147 156 129 193 164 182 266 157 168 228 186 180 145 11 95 278 260 259 610 689 149 344 265 213 95 111 0 0 3 1 0 0 0 0 0 87 0 0 1 193 COG1198(Primosomal protein N (replication factor Y) - superfamily II helicase) 516 499 523 483 39 47 111 173 76 66 64 88 62 130 109 95 176 179 121 150 170 129 303 160 202 254 195 153 146 61 136 287 277 192 584 716 157 761 205 193 100 96 0 0 2 4 0 3 4 0 0 80 1 0 0 146 COG0019(Diaminopimelate decarboxylase) 572 415 358 480 27 38 146 123 76 83 65 81 65 111 94 106 158 159 124 151 160 183 325 205 205 285 165 172 164 38 158 294 250 218 552 791 157 808 217 208 82 62 0 0 4 2 0 4 0 0 2 93 2 0 0 165 COG3437(Response regulator containing a CheY-like receiver domain and an HD-GYP domain) 4194 220 305 139 27 35 44 127 25 55 75 42 40 152 61 36 96 147 79 114 67 106 141 80 49 248 148 99 63 49 88 131 102 61 215 233 300 855 81 91 42 37 0 0 1 0 0 1 2 2 0 31 0 4 0 61 COG0760(Parvulin-like peptidyl-prolyl isomerase) 720 431 573 397 65 42 122 143 84 79 77 88 41 149 101 63 146 115 117 152 137 187 265 150 185 186 152 132 151 42 137 268 268 197 672 668 192 797 200 261 100 109 0 0 1 0 2 1 1 2 2 51 0 1 0 166 COG1178(ABC-type Fe3+ transport system, permease component) 752 396 337 428 33 44 109 136 54 35 36 77 48 106 78 87 87 131 130 168 182 160 336 175 207 129 168 184 155 47 160 383 297 254 690 750 163 722 185 272 117 89 0 0 1 3 2 0 0 2 2 94 2 3 0 166 COG1009(NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit) 473 356 427 417 27 38 126 131 43 63 33 80 43 183 126 107 189 178 86 202 196 206 347 199 177 386 176 200 172 32 155 245 269 187 415 660 138 986 220 150 107 98 0 0 2 4 1 0 1 2 0 76 2 0 0 221 COG1197(Transcription-repair coupling factor (superfamily II helicase)) 435 271 447 287 50 51 110 111 71 50 45 62 55 163 70 53 219 197 139 162 173 175 267 155 188 541 157 141 149 49 163 270 226 178 475 520 163 1503 198 187 107 73 0 1 4 2 2 0 1 0 0 85 1 0 0 133 COG0168(Trk-type K+ transport systems, membrane components) 478 543 453 549 48 56 143 184 80 80 65 94 48 141 107 103 103 81 144 213 143 144 309 194 169 18 156 155 158 46 138 333 266 198 709 750 136 557 225 259 124 107 0 0 2 1 1 1 2 1 0 85 1 1 4 156 COG0747(ABC-type dipeptide transport system, periplasmic component) 1096 345 375 390 25 74 66 96 64 52 32 67 69 221 73 73 176 222 148 178 154 145 271 166 146 513 164 150 125 41 104 239 191 151 496 528 184 892 142 193 68 98 0 0 2 2 0 0 2 0 0 86 0 2 3 150 COG0305(Replicative DNA helicase) 330 297 351 359 42 40 132 198 51 65 76 71 81 110 86 104 170 191 142 154 186 160 357 187 184 517 144 194 195 104 167 283 277 181 490 572 162 1031 171 191 99 75 4 2 1 0 2 1 0 0 0 89 3 0 3 159 COG1217(Predicted membrane GTPase involved in stress response) 534 256 294 301 57 41 145 146 90 111 69 88 59 161 103 105 176 206 146 196 168 127 245 190 149 398 166 150 137 42 122 293 238 207 552 435 211 1302 190 168 102 104 2 0 1 1 0 0 1 3 0 102 0 0 0 141 COG0329(Dihydrodipicolinate synthase/N-acetylneuraminate lyase) 886 401 376 453 33 50 139 144 74 45 55 68 42 125 83 105 164 170 147 172 140 177 297 190 153 251 149 168 143 35 134 259 249 190 593 660 121 757 180 178 97 94 2 0 2 0 0 0 4 0 0 94 2 3 2 167 COG0312(Predicted Zn-dependent proteases and their inactivated homologs) 836 364 386 343 22 41 131 206 55 61 51 92 45 152 105 135 180 176 130 182 217 162 327 176 174 331 181 168 216 53 161 250 281 186 481 499 134 647 208 166 111 99 3 0 1 2 2 0 0 4 0 82 0 0 4 191 COG0056(F0F1-type ATP synthase, alpha subunit) 465 462 488 416 55 46 146 150 71 62 53 103 78 152 95 118 144 167 115 144 187 178 273 175 195 317 162 187 166 47 141 323 257 178 615 676 145 685 173 191 74 82 1 1 0 0 0 0 2 0 2 102 0 0 0 136 COG0472(UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase) 562 325 396 402 47 59 111 113 58 63 64 75 55 122 105 89 184 244 112 130 161 176 306 167 166 485 159 193 135 58 136 282 228 219 523 644 157 901 175 192 86 84 0 2 0 2 0 0 1 1 3 75 0 1 0 135 COG0388(Predicted amidohydrolase) 854 293 493 398 44 34 142 103 39 34 32 43 42 123 64 65 175 188 115 135 202 154 286 183 209 497 126 154 163 76 127 226 148 119 345 498 186 1358 168 156 65 62 0 0 0 0 1 1 0 0 4 67 0 2 0 137 COG1200(RecG-like helicase) 539 360 461 395 49 46 113 112 58 50 59 65 43 175 110 109 246 181 111 144 176 156 330 177 200 323 158 164 179 56 170 270 250 181 552 616 161 826 180 182 83 72 0 2 0 0 2 0 2 1 2 68 0 0 0 135 COG0607(Rhodanese-related sulfurtransferase) 1011 320 420 340 40 39 97 124 57 74 58 81 39 205 105 114 146 186 116 137 154 151 285 160 159 333 159 131 110 63 127 244 230 126 387 478 170 1245 133 164 94 65 0 0 1 3 1 2 0 1 0 62 1 1 0 138 COG0582(Integrase) 1513 283 300 289 39 61 83 175 56 93 118 50 65 282 129 90 131 164 188 124 128 127 245 160 163 269 123 117 108 59 139 172 137 104 263 341 226 1351 144 87 63 65 0 1 1 0 1 0 3 0 0 71 1 0 1 149 COG0473(Isocitrate/isopropylmalate dehydrogenase) 643 433 364 480 29 45 151 121 60 98 60 95 73 184 98 123 123 173 107 166 166 163 334 191 189 257 165 166 166 47 116 283 275 158 518 540 134 793 198 185 76 73 0 2 0 0 0 5 2 2 0 59 0 2 0 155 COG0055(F0F1-type ATP synthase, beta subunit) 463 464 494 438 59 48 153 105 51 74 41 63 65 167 72 113 169 154 86 172 154 151 291 211 176 306 168 165 175 54 121 308 256 170 660 641 159 602 174 194 95 89 0 4 4 0 4 0 0 0 0 102 0 1 0 135 COG1530(Ribonucleases G and E) 633 357 371 391 44 44 115 133 56 45 85 88 41 126 100 99 165 172 127 126 145 142 278 169 170 264 160 167 152 42 146 271 248 170 635 577 173 988 166 207 97 93 2 2 0 0 2 0 1 2 0 89 1 0 0 141 COG2609(Pyruvate dehydrogenase complex, dehydrogenase (E1) component) 686 517 481 413 18 12 91 126 53 53 33 76 46 151 88 109 248 246 143 116 154 160 277 176 150 467 138 172 160 32 116 271 229 147 448 601 122 769 163 160 101 71 1 0 1 2 0 1 0 1 4 69 2 0 0 127 COG3291(FOG: PKD repeat) 1412 201 533 226 104 69 60 141 118 47 108 50 71 167 71 69 159 130 93 141 169 213 282 119 138 238 126 136 137 92 105 265 261 130 203 425 252 879 132 267 110 114 0 2 0 2 0 2 0 2 0 68 0 0 0 155 COG0488(ATPase components of ABC transporters with duplicated ATPase domains) 1155 166 232 165 65 86 61 118 96 85 104 63 82 272 95 77 286 309 180 125 107 88 175 95 103 589 145 110 93 64 91 215 128 132 345 336 201 1426 180 232 64 61 0 0 2 0 4 0 1 1 0 56 0 0 0 68 COG1034(NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)) 1087 388 358 412 10 36 130 169 53 59 42 93 52 118 77 138 206 190 88 156 141 81 236 129 156 330 128 157 141 13 115 228 221 162 493 627 128 921 141 167 74 55 0 0 0 6 2 0 0 0 0 59 1 0 0 153 COG0741(Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)) 1229 350 357 377 23 32 106 121 59 45 55 64 44 200 81 117 178 169 120 155 187 157 259 156 147 141 146 159 137 26 117 250 238 190 536 549 189 790 154 163 62 61 0 0 0 2 0 0 1 0 0 69 2 1 0 127 COG0534(Na+-driven multidrug efflux pump) 861 423 484 367 49 38 151 172 86 86 110 103 73 179 107 111 78 80 148 117 138 140 311 159 188 36 157 151 159 24 112 265 262 176 567 606 147 658 135 218 105 125 1 4 0 2 0 0 0 1 0 70 2 0 0 156 COG0520(Selenocysteine lyase) 530 353 493 413 46 50 104 98 64 41 39 80 40 137 115 80 139 105 123 140 197 166 355 218 134 390 142 172 195 64 116 257 245 217 476 646 166 633 191 216 97 120 0 0 0 0 2 0 2 1 2 104 0 3 2 159 COG5009(Membrane carboxypeptidase/penicillin-binding protein) 777 388 392 383 72 26 156 180 79 70 57 82 51 107 85 141 136 113 132 130 128 106 239 143 158 87 143 191 155 21 146 286 304 218 703 706 124 608 182 214 109 105 0 3 2 0 0 0 0 0 2 84 0 0 1 141 COG1063(Threonine dehydrogenase and related Zn-dependent dehydrogenases) 1482 284 393 315 24 53 88 115 60 66 36 46 71 266 96 95 159 155 125 166 165 127 233 135 128 286 139 125 115 35 95 264 189 160 454 501 106 799 146 181 60 85 0 3 0 1 3 1 0 0 2 57 0 1 0 172 COG4663(TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component) 398 500 384 515 27 27 139 178 56 70 49 98 75 229 82 144 164 102 149 201 136 174 199 171 164 99 208 177 138 18 116 303 321 243 802 729 131 280 195 195 101 113 0 2 0 0 3 0 0 0 4 98 1 1 0 151 COG0644(Dehydrogenases (flavoproteins)) 794 400 395 379 27 59 116 119 63 76 45 77 40 167 97 84 69 60 100 199 207 209 357 194 185 163 120 148 132 90 155 306 260 188 460 595 124 652 229 203 112 91 0 1 1 1 2 1 0 0 0 83 1 0 0 216 COG0483(Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family) 428 399 445 394 33 55 140 143 48 73 56 69 48 187 97 89 148 127 113 160 161 150 325 175 210 310 113 168 148 46 150 269 250 197 587 561 166 837 171 170 93 92 0 0 1 2 0 3 3 1 4 102 2 1 2 128 COG0405(Gamma-glutamyltransferase) 947 444 660 392 48 58 149 133 63 77 44 65 53 235 127 90 88 40 123 159 182 159 331 131 168 199 163 144 160 57 108 224 205 167 523 550 69 551 176 199 61 85 2 1 0 0 4 1 0 2 0 77 1 0 4 135 COG2812(DNA polymerase III, gamma/tau subunits) 371 377 407 405 51 40 146 95 64 58 63 86 42 131 78 87 191 177 86 178 185 125 300 166 175 298 122 202 122 46 163 302 231 188 583 616 137 839 194 227 103 68 2 2 2 2 0 0 1 0 2 104 3 0 0 152 COG3808(Inorganic pyrophosphatase) 284 454 564 425 42 49 150 157 80 62 47 88 62 164 111 107 140 217 109 220 171 189 330 169 208 333 162 189 127 44 106 268 298 230 547 692 137 227 170 182 125 89 0 0 0 0 1 4 2 2 0 77 0 0 0 160 COG0057(Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase) 505 350 377 380 51 55 136 90 63 64 89 65 33 127 103 110 146 133 107 180 200 157 353 190 175 221 155 154 148 49 104 274 238 202 506 553 210 861 194 232 87 78 1 2 0 0 1 0 3 0 0 77 1 0 1 134 COG0661(Predicted unusual protein kinase) 545 398 399 445 58 77 114 155 70 72 54 86 67 99 89 93 119 101 107 156 194 172 313 178 223 226 156 160 172 91 195 273 212 177 477 568 158 684 235 183 80 81 0 4 4 0 3 0 1 2 0 95 0 0 0 95 COG0141(Histidinol dehydrogenase) 436 396 335 455 30 51 152 143 59 76 47 76 58 164 87 126 143 148 127 179 175 149 244 176 150 159 170 165 141 38 158 296 295 221 588 683 134 640 168 225 91 76 0 1 0 0 0 2 0 3 2 88 3 0 2 170 COG0034(Glutamine phosphoribosylpyrophosphate amidotransferase) 456 404 472 437 44 56 119 159 69 60 69 68 39 148 72 69 90 123 99 160 173 167 309 188 198 158 88 158 135 54 154 238 258 178 520 626 187 890 171 180 75 83 0 0 1 1 0 0 0 3 0 92 0 3 8 132 COG1529(Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs) 1252 302 492 391 29 66 53 89 51 31 37 23 65 311 82 111 169 175 186 222 156 212 302 156 186 459 173 149 84 29 79 157 119 102 260 516 124 735 105 124 50 35 0 0 0 0 0 0 0 1 0 21 0 1 1 145 COG0173(Aspartyl-tRNA synthetase) 474 356 425 384 42 38 115 141 56 77 43 75 61 149 81 107 130 137 89 166 156 151 310 168 240 258 152 169 156 56 131 263 265 204 614 597 194 606 159 221 79 81 1 0 2 0 0 2 0 3 2 90 1 2 0 125 COG0793(Periplasmic protease) 614 419 470 411 60 40 135 134 66 56 68 78 55 123 99 82 103 110 114 119 163 169 334 184 237 202 166 193 157 71 123 255 189 174 501 555 165 755 142 193 77 58 2 0 0 3 0 2 2 1 0 70 0 1 2 102 COG1219(ATP-dependent protease Clp, ATPase subunit) 469 352 365 367 49 41 134 165 63 55 66 79 51 109 89 104 140 166 92 156 201 153 282 193 215 287 129 157 154 56 152 273 222 185 498 580 142 765 181 161 113 98 0 1 2 0 2 0 2 4 0 86 0 0 1 146 COG0617(tRNA nucleotidyltransferase/poly(A) polymerase) 606 374 412 405 38 42 120 97 57 48 73 100 12 139 97 89 136 159 115 152 147 117 285 179 153 296 121 165 161 61 155 274 238 175 488 585 200 715 180 182 75 63 0 1 0 2 2 1 3 0 1 89 0 1 0 135 COG2171(Tetrahydrodipicolinate N-succinyltransferase) 604 383 367 412 30 36 127 136 65 70 83 69 44 148 99 97 138 126 106 132 168 147 260 170 182 271 144 151 120 34 129 233 228 183 580 559 130 905 170 165 65 61 0 0 0 0 0 0 1 4 0 68 4 0 0 113 COG0342(Preprotein translocase subunit SecD) 489 387 430 383 66 47 134 114 53 79 60 61 48 127 59 100 134 153 111 177 164 129 297 183 168 234 180 161 155 42 149 233 189 175 527 559 139 806 150 217 94 86 0 0 2 0 0 5 0 0 0 96 1 0 0 150 COG0403(Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain) 391 345 380 327 23 32 105 118 60 45 51 83 56 140 111 96 116 114 95 149 215 189 337 216 178 272 145 184 206 100 142 283 231 167 513 496 136 838 176 209 69 76 0 0 0 0 0 6 1 1 2 113 2 2 6 136 COG0591(Na+/proline symporter) 1924 302 574 226 43 23 106 100 55 50 73 69 46 164 39 66 87 114 92 122 90 171 213 98 101 136 108 133 77 44 88 195 169 107 320 351 199 995 140 175 77 49 2 0 0 0 3 2 0 0 2 55 0 0 0 82 COG0773(UDP-N-acetylmuramate-alanine ligase) 510 353 401 362 51 44 122 127 61 61 73 70 26 127 93 81 165 176 111 98 184 126 286 152 142 309 136 140 159 52 113 280 225 212 550 609 180 728 187 202 89 88 0 2 1 3 0 0 1 0 4 61 1 0 0 110 COG0442(Prolyl-tRNA synthetase) 403 377 418 354 38 34 117 140 61 81 63 61 31 107 88 88 153 178 120 132 202 187 269 169 153 337 184 172 138 61 118 284 227 170 498 527 224 764 161 178 104 57 0 0 0 0 0 2 0 0 2 78 0 2 0 118 COG1154(Deoxyxylulose-5-phosphate synthase) 427 392 343 362 35 56 107 154 59 84 54 63 54 163 68 77 141 169 120 143 141 117 315 130 190 305 137 156 137 46 145 257 243 171 540 648 114 825 168 184 64 111 0 0 1 1 0 2 0 2 0 75 0 0 0 120 COG0208(Ribonucleotide reductase, beta subunit) 328 267 241 278 18 28 112 344 97 82 137 110 159 102 76 84 154 155 147 216 133 156 369 207 175 372 170 181 226 156 127 266 278 210 399 496 93 380 186 136 102 127 0 0 3 0 6 1 0 0 0 101 0 0 2 212 COG2175(Probable taurine catabolism dioxygenase) 684 488 519 583 39 35 127 167 63 60 48 54 45 237 107 112 98 79 154 212 173 123 296 192 205 80 143 156 137 23 129 206 208 177 573 810 96 125 146 139 67 84 0 4 0 2 0 3 1 1 0 77 2 2 0 111 COG1280(Putative threonine efflux protein) 1597 337 294 326 14 27 111 128 57 55 72 70 38 134 89 80 121 133 108 143 142 118 220 159 118 135 151 122 128 27 125 246 212 190 527 645 101 429 140 150 83 79 1 0 0 3 0 2 2 0 2 59 1 0 2 147 COG2207(AraC-type DNA-binding domain-containing proteins) 4961 114 85 97 37 27 30 37 23 44 64 18 32 114 36 35 65 95 79 38 74 61 89 58 53 114 67 41 49 38 51 64 41 35 136 102 186 854 57 60 18 28 0 0 0 0 0 0 0 0 0 24 1 0 3 28 COG2198(FOG: HPt domain) 3279 298 163 190 13 36 54 61 16 22 112 30 19 115 44 44 83 105 52 59 74 76 124 86 78 159 72 56 66 44 74 89 66 57 133 176 358 1537 61 60 19 19 0 0 0 0 0 0 0 2 0 22 0 0 0 39 COG0138(AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)) 443 405 416 396 28 53 106 128 63 58 40 75 47 197 112 70 132 125 86 160 194 125 303 160 168 209 131 152 190 44 100 260 244 161 512 607 126 746 187 204 97 80 0 2 0 2 0 0 0 0 0 73 0 0 0 119 COG1003(Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain) 420 329 362 325 40 34 83 111 65 52 52 87 74 114 106 102 125 134 102 154 183 174 343 172 176 247 144 201 216 96 162 286 264 155 480 515 118 738 173 205 63 67 0 0 0 0 0 3 1 2 4 105 1 2 6 137 COG0037(Predicted ATPase of the PP-loop superfamily implicated in cell cycle control) 502 358 408 427 41 39 127 153 64 69 88 85 51 151 80 122 137 125 111 172 149 132 284 141 125 275 157 126 130 54 144 242 229 170 464 635 159 656 148 224 90 64 2 3 0 0 1 1 1 0 0 53 0 0 1 137 COG1192(ATPases involved in chromosome partitioning) 988 357 336 348 27 30 98 102 41 36 37 44 32 131 59 66 133 166 90 148 132 121 222 126 127 332 126 123 103 34 85 204 182 158 421 567 156 1223 131 140 88 51 1 1 2 0 0 0 0 0 0 67 0 0 1 90 COG0215(Cysteinyl-tRNA synthetase) 422 370 403 323 32 44 114 123 66 64 46 90 48 153 97 80 233 219 79 158 165 125 274 142 161 427 165 164 150 62 128 233 200 166 437 523 157 694 145 157 69 95 1 0 0 0 2 1 0 0 2 84 0 1 0 171 COG1171(Threonine dehydratase) 759 377 458 386 41 61 85 123 66 94 48 90 51 190 92 91 76 82 115 160 141 126 279 171 138 116 120 101 133 45 127 286 197 164 523 556 83 780 185 178 91 77 0 0 0 2 0 0 3 1 0 77 1 2 4 107 COG4775(Outer membrane protein/protective antigen OMA87) 496 373 484 434 54 51 107 97 59 48 34 82 44 99 139 72 108 87 97 167 163 173 350 156 181 173 129 155 130 46 121 261 211 172 612 625 205 506 173 204 75 82 0 2 0 0 0 1 2 0 6 71 3 0 0 117 COG0735(Fe2+/Zn2+ uptake regulation proteins) 428 389 352 422 27 43 133 122 49 53 58 79 66 108 80 102 123 146 87 148 150 133 288 198 165 180 152 172 173 44 138 264 247 218 577 609 126 624 172 161 87 83 1 0 1 0 2 0 0 0 3 56 0 3 1 168 COG0551(Zn-finger domain associated with topoisomerase type I) 582 328 349 344 21 49 189 135 61 65 29 94 53 54 79 90 130 160 86 175 218 197 273 183 190 188 155 146 164 18 161 228 238 138 513 561 191 714 129 107 68 70 0 0 0 2 0 0 4 0 0 80 1 1 0 185 COG0601(ABC-type dipeptide/oligopeptide/nickel transport systems, permease components) 698 316 409 363 28 75 70 91 53 41 41 46 58 168 119 77 121 169 146 124 147 141 296 164 151 407 183 137 128 37 102 258 176 159 475 592 113 630 114 178 64 96 0 2 1 0 0 0 0 0 0 84 1 0 1 131 COG0389(Nucleotidyltransferase/DNA polymerase involved in DNA repair) 801 411 400 344 46 41 122 96 48 35 61 57 29 117 87 57 113 144 107 145 146 125 269 160 141 303 136 128 122 40 113 280 228 170 502 510 136 623 160 179 81 129 0 0 0 0 2 3 0 0 0 74 4 0 1 145 COG0018(Arginyl-tRNA synthetase) 381 402 448 366 40 33 128 106 56 54 50 70 38 104 83 83 151 187 92 137 173 165 264 145 165 288 135 164 132 48 133 235 243 204 521 601 195 650 143 162 91 68 2 0 0 1 0 3 2 0 2 72 1 0 0 148 COG3210(Large exoproteins involved in heme utilization or adhesion) 1300 93 373 157 76 100 48 184 43 37 127 58 95 114 52 75 181 234 133 114 98 141 224 114 100 405 120 83 90 127 80 177 231 83 149 209 139 1461 91 110 88 45 0 0 0 0 2 0 0 1 0 40 0 1 0 112 COG0468(RecA/RadA recombinase) 319 307 354 335 48 22 136 128 45 56 55 78 66 115 74 74 115 122 91 170 149 150 319 196 211 450 168 151 177 117 131 252 238 182 460 549 153 565 166 166 92 84 6 2 0 0 2 0 0 0 4 69 2 1 0 185 COG1011(Predicted hydrolase (HAD superfamily)) 779 385 433 359 39 44 113 126 51 51 65 73 38 139 125 80 120 140 94 129 119 139 262 173 123 177 144 147 121 23 98 239 208 174 473 593 168 660 101 166 74 84 0 2 1 0 0 0 1 0 0 77 2 0 0 113 COG2857(Cytochrome c1) 607 387 362 455 16 37 133 127 34 84 32 105 81 106 75 105 111 139 86 168 161 132 233 188 135 215 136 135 146 31 120 221 218 182 501 548 110 695 156 160 78 73 0 0 1 0 0 0 1 0 0 76 1 1 0 131 COG0045(Succinyl-CoA synthetase, beta subunit) 530 440 389 402 36 35 143 135 37 58 57 74 53 135 90 92 128 138 94 137 112 157 263 146 121 226 144 144 134 19 117 241 254 188 513 639 147 513 168 172 92 83 0 4 0 2 4 0 0 3 0 88 1 0 0 134 COG0050(GTPases - translation elongation factors) 362 321 355 311 47 41 100 104 54 65 42 61 66 290 99 92 178 160 106 151 182 127 265 157 163 261 121 160 153 37 131 238 203 153 423 484 140 912 170 150 79 85 3 3 0 2 0 0 0 0 0 78 1 3 0 129 COG1208(Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)) 507 378 400 419 29 37 96 141 37 41 52 57 42 90 102 55 156 197 60 156 167 165 270 201 165 371 132 163 145 57 136 252 198 170 425 586 204 497 146 140 82 71 0 1 0 0 2 0 0 0 2 68 2 3 0 133 COG0358(DNA primase (bacterial type)) 414 358 394 349 34 49 112 112 67 61 71 57 36 136 82 77 159 152 77 121 125 123 262 125 154 302 143 169 131 57 102 276 260 153 461 588 192 759 144 185 99 86 0 0 2 0 2 0 2 0 3 51 0 0 0 126 COG0706(Preprotein translocase subunit YidC) 373 423 403 396 44 33 132 135 53 63 49 73 35 117 118 81 127 128 110 135 154 146 279 164 149 237 125 149 137 29 113 221 229 172 583 626 121 558 165 187 91 104 2 5 0 0 0 0 0 0 0 63 0 0 5 120 COG1004(Predicted UDP-glucose 6-dehydrogenase) 546 300 344 327 43 44 134 152 53 56 62 72 44 97 90 50 111 155 87 169 157 131 298 188 190 412 142 176 152 96 117 240 220 162 401 444 130 610 179 177 84 86 0 2 5 1 4 1 0 1 4 69 0 0 4 138 COG0504(CTP synthase (UTP-ammonia lyase)) 376 318 412 356 45 23 116 134 53 50 61 59 33 94 85 87 184 171 98 142 155 140 287 172 169 278 146 166 163 53 91 246 228 182 462 572 150 613 153 187 112 72 0 0 1 1 0 1 0 2 0 88 1 0 0 150 COG0195(Transcription elongation factor) 388 431 371 368 45 41 118 124 53 75 26 74 45 102 94 53 148 148 84 160 157 145 266 140 154 240 148 155 168 28 102 261 209 181 516 561 172 582 141 186 95 89 0 0 0 1 0 0 0 0 0 94 4 1 0 139 COG0511(Biotin carboxyl carrier protein) 989 352 382 295 30 36 95 156 52 98 66 70 30 192 64 90 89 88 103 110 120 120 207 123 132 147 98 115 105 30 103 187 156 134 445 481 101 1116 138 120 67 76 0 0 0 1 2 0 0 0 0 74 1 0 0 92 COG2072(Predicted flavoprotein involved in K+ transport) 921 363 437 367 40 45 120 119 70 88 65 82 48 232 99 105 79 85 167 149 123 168 240 119 140 155 120 112 133 32 65 243 201 142 455 654 93 384 134 173 90 49 4 1 0 0 0 2 0 2 0 60 0 0 0 103 COG1414(Transcriptional regulator) 2093 178 261 195 29 35 53 63 46 55 57 41 51 212 68 57 144 176 124 128 93 86 149 90 96 290 124 74 59 22 80 168 121 89 208 303 63 1257 107 110 56 44 0 4 0 0 0 1 0 0 0 39 0 0 0 66 COG1472(Beta-glucosidase-related glycosidases) 537 361 458 331 117 54 133 137 90 95 84 93 36 142 110 69 75 129 137 135 118 153 230 141 108 151 126 143 120 92 83 242 238 150 554 501 122 556 164 250 82 63 0 0 0 0 0 0 0 0 0 44 2 0 1 103 COG0104(Adenylosuccinate synthase) 452 332 392 298 37 35 147 130 45 49 37 61 47 144 65 94 157 153 83 125 208 132 258 186 197 273 133 165 150 60 113 250 239 149 479 510 145 616 132 187 71 89 0 1 1 0 1 0 0 0 4 61 1 2 1 137 COG2208(Serine phosphatase RsbU, regulator of sigma subunit) 1255 340 310 301 34 39 87 150 58 49 67 96 33 102 66 55 101 118 75 108 164 156 234 151 190 209 171 124 143 58 149 147 154 92 305 352 269 797 121 127 53 75 0 0 0 0 0 0 0 1 4 54 0 0 4 77 COG0489(ATPases involved in chromosome partitioning) 727 317 300 275 26 54 99 91 58 55 58 62 43 134 78 92 120 133 117 121 112 155 224 112 171 319 140 139 109 72 96 225 170 141 406 517 93 982 136 165 77 71 1 2 0 0 3 0 0 1 2 71 1 1 0 147 COG0015(Adenylosuccinate lyase) 561 332 389 390 40 37 137 98 46 38 58 53 49 105 94 76 128 147 107 138 150 126 300 159 190 272 124 145 142 36 139 223 197 162 421 520 117 682 147 145 78 72 0 1 0 0 0 1 0 4 0 83 0 2 1 132 COG3383(Uncharacterized anaerobic dehydrogenase) 1341 281 347 314 8 10 80 154 65 54 43 53 65 108 92 121 171 131 104 170 122 110 138 106 94 201 120 83 69 7 60 182 165 97 410 670 94 777 140 130 81 56 0 0 2 0 0 0 0 0 0 31 0 0 0 113 COG0566(rRNA methylases) 313 267 311 284 65 47 117 104 72 54 52 60 32 151 105 93 183 224 112 151 136 144 275 160 172 401 111 121 147 66 119 243 185 156 426 431 89 898 156 175 84 51 0 2 0 0 0 1 4 0 0 70 1 0 1 134 COG4799(Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)) 309 282 492 298 51 50 118 94 51 60 58 36 57 213 78 65 153 111 141 157 146 179 335 117 156 247 128 148 130 35 102 247 221 167 379 521 77 750 126 218 114 91 0 0 0 0 0 0 0 0 0 122 0 1 0 120 COG1304(L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases) 469 484 289 464 25 36 129 101 37 49 37 57 63 139 62 69 120 102 86 163 102 129 256 155 152 176 108 130 152 6 123 280 226 181 513 575 122 585 139 183 83 108 0 0 6 4 0 0 3 0 0 101 2 0 0 127 COG0499(S-adenosylhomocysteine hydrolase) 342 400 425 398 33 26 110 128 62 64 37 58 43 121 78 84 131 141 132 162 170 142 289 152 140 254 154 143 117 40 117 252 232 162 534 495 105 515 153 178 89 83 0 0 0 0 0 0 1 0 2 80 0 0 1 130 COG1126(ABC-type polar amino acid transport system, ATPase component) 1687 239 247 276 23 43 88 99 43 38 42 85 46 132 68 64 137 161 109 145 93 97 170 118 117 237 114 111 67 10 79 184 179 134 354 472 103 699 149 131 67 60 0 0 0 1 1 1 0 0 0 54 0 0 5 120 COG0652(Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family) 464 303 390 310 56 60 95 79 74 57 64 57 42 95 110 85 156 141 91 122 186 157 316 172 173 283 122 155 132 92 148 237 209 146 388 442 135 643 158 181 101 77 2 0 0 1 1 0 0 2 0 63 0 2 0 121 COG4176(ABC-type proline/glycine betaine transport system, permease component) 753 429 353 444 14 29 105 187 60 75 42 72 76 79 82 107 94 93 82 152 133 129 191 118 136 57 107 135 121 6 114 233 199 184 581 828 105 367 157 149 59 83 0 2 2 0 0 0 4 1 4 60 0 0 0 95 COG0668(Small-conductance mechanosensitive channel) 1093 376 344 322 40 36 74 109 48 40 31 37 33 100 42 57 116 122 94 98 131 121 269 111 112 89 124 113 132 39 113 205 207 117 391 433 205 985 104 130 83 50 0 0 1 1 0 1 0 2 0 72 2 2 0 114 COG0372(Citrate synthase) 587 316 371 340 31 33 111 131 41 40 38 69 40 140 102 86 131 151 99 130 157 140 289 154 191 350 116 133 126 50 106 236 186 135 410 500 137 636 163 137 81 57 2 2 1 3 0 0 0 0 2 74 0 2 1 98 COG0649(NADH:ubiquinone oxidoreductase 49 kD subunit 7) 352 310 353 410 13 35 106 85 37 53 30 54 44 172 83 94 155 164 96 154 167 193 308 163 177 347 150 153 147 34 179 234 218 159 440 555 99 396 153 125 87 73 3 0 0 0 0 0 1 0 0 81 1 0 1 172 COG0112(Glycine/serine hydroxymethyltransferase) 465 328 369 346 31 35 106 105 52 67 55 90 41 117 74 78 134 156 66 121 154 119 278 144 170 303 119 139 143 57 110 232 230 158 452 555 140 645 154 149 76 78 0 2 0 1 0 2 0 3 2 56 0 0 0 93 COG0225(Peptide methionine sulfoxide reductase) 529 360 358 402 47 46 133 80 50 42 34 49 16 105 73 71 129 113 82 114 146 166 266 141 150 165 141 126 175 46 147 251 205 131 499 513 159 619 146 176 82 89 1 0 1 0 1 0 0 0 0 73 1 1 2 119 COG0811(Biopolymer transport proteins) 768 545 501 380 38 41 126 144 49 50 59 53 60 133 87 69 97 84 89 119 97 124 219 122 148 109 132 105 102 38 88 251 223 138 555 502 126 424 142 153 66 60 0 0 0 1 0 0 1 4 0 67 0 0 0 72 COG0825(Acetyl-CoA carboxylase alpha subunit) 433 315 422 382 29 31 158 113 62 59 43 62 67 119 90 85 113 88 89 161 139 122 253 164 148 100 148 132 125 42 127 261 218 145 572 558 120 524 159 205 77 91 1 2 0 0 3 0 1 0 6 77 1 2 0 97 COG0527(Aspartokinases) 575 356 330 364 35 28 109 116 46 43 42 58 37 135 96 88 150 167 89 134 122 103 233 169 149 261 108 125 132 43 114 233 208 145 420 526 128 620 141 156 78 58 0 1 0 0 1 4 1 0 0 61 0 0 2 146 COG1345(Flagellar capping protein) 3867 78 147 90 11 28 35 118 17 39 68 15 40 74 26 23 53 91 58 27 85 63 192 59 58 139 88 93 67 58 43 114 98 53 164 186 35 644 71 92 35 46 0 0 0 1 0 2 2 0 2 24 1 0 0 51 COG1052(Lactate dehydrogenase and related dehydrogenases) 814 428 295 413 21 28 107 111 53 32 34 44 48 117 67 97 112 95 85 147 109 96 251 155 155 128 113 171 141 14 132 212 236 129 564 458 165 463 132 151 90 77 0 3 2 1 2 0 0 0 0 79 1 1 0 87 COG2873(O-acetylhomoserine sulfhydrylase) 390 381 279 375 40 43 108 116 50 68 44 70 63 192 68 85 123 106 112 128 122 176 240 164 146 234 141 143 127 38 127 235 207 173 433 540 91 563 163 160 76 61 0 0 0 4 2 0 0 0 0 85 2 0 0 132 COG1020(Non-ribosomal peptide synthetase modules and related proteins) 5584 73 91 74 35 29 2 20 16 8 11 9 23 64 13 43 38 31 38 33 19 29 48 25 33 75 40 26 29 28 26 36 35 27 64 118 88 318 31 33 9 20 2 0 0 0 0 2 0 0 0 7 0 0 0 21 COG0702(Predicted nucleoside-diphosphate-sugar epimerases) 1008 339 393 333 32 42 82 96 74 40 44 48 38 100 79 61 108 138 94 100 132 140 233 156 134 233 111 107 133 59 96 238 174 122 424 483 70 558 156 139 66 61 0 2 0 0 0 1 0 0 0 56 1 1 0 86 COG0179(2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)) 996 293 346 281 28 42 95 154 52 68 54 59 60 132 58 76 189 153 107 127 110 134 217 144 108 226 116 122 107 31 61 212 166 136 365 441 66 687 116 182 61 52 0 2 1 0 0 0 0 0 0 51 2 0 0 106 COG0769(UDP-N-acetylmuramyl tripeptide synthase) 472 249 284 346 39 31 81 110 45 29 42 64 32 86 69 78 181 205 95 92 133 103 252 153 172 277 134 144 130 25 118 187 194 162 430 556 129 836 142 164 72 71 2 4 0 0 0 1 0 1 0 47 1 1 2 100 COG2801(Transposase and inactivated derivatives) 1858 219 74 75 120 60 11 55 43 26 57 12 38 210 62 42 97 74 192 24 17 21 30 17 4 194 25 12 11 26 8 11 4 12 28 36 373 3127 5 6 2 9 0 0 0 0 0 0 0 0 0 13 0 1 0 4 COG0280(Phosphotransacetylase) 738 324 253 330 24 23 108 129 59 52 49 75 61 79 66 107 97 99 103 125 128 130 184 121 103 106 120 114 103 16 107 187 230 151 475 641 100 779 146 154 73 61 0 2 0 2 0 1 0 6 0 65 0 0 0 111 COG0764(3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases) 859 363 411 375 20 40 115 149 42 61 34 58 39 87 71 76 79 79 70 166 100 131 264 157 120 123 100 136 110 24 102 259 197 172 484 524 68 382 178 160 77 63 0 2 0 0 0 1 0 0 0 64 0 1 0 121 COG1754(Uncharacterized C-terminal domain of topoisomerase IA) 328 333 346 325 28 47 120 104 81 52 37 74 40 80 89 112 144 136 91 132 185 128 239 177 150 227 107 111 135 33 140 176 203 125 428 509 107 922 118 122 48 63 2 0 0 2 0 0 2 0 0 61 2 1 0 90 COG0308(Aminopeptidase N) 599 188 426 164 69 48 70 87 74 71 73 49 55 145 74 90 115 140 106 105 135 135 276 149 144 285 113 151 110 74 97 237 180 137 328 336 131 910 134 190 91 58 0 0 7 0 0 0 0 0 0 59 0 0 0 86 COG0419(ATPase involved in DNA repair) 589 157 286 182 71 62 52 281 73 95 113 68 102 114 51 38 121 148 81 141 134 168 244 119 156 512 106 145 162 266 114 165 145 123 193 337 132 686 138 118 65 51 0 1 0 1 2 0 0 0 0 28 0 1 0 159 COG1702(Phosphate starvation-inducible protein PhoH, predicted ATPase) 326 264 279 268 31 32 89 238 81 71 87 67 71 61 53 93 143 162 106 144 148 140 277 154 175 413 131 161 183 106 161 218 201 173 337 404 80 477 164 146 84 61 0 0 0 0 0 2 2 1 0 66 2 1 0 157 COG0486(Predicted GTPase) 407 393 395 389 32 40 125 122 55 57 68 87 72 160 71 60 113 85 79 134 133 140 274 149 156 147 145 125 121 34 105 208 258 163 494 524 121 356 152 193 83 70 1 0 1 0 0 2 3 1 6 53 0 1 1 123 COG0703(Shikimate kinase) 453 338 304 316 34 42 78 138 48 45 42 66 33 111 72 54 145 154 93 103 128 152 200 157 160 231 99 145 104 47 125 206 191 140 444 487 113 862 146 174 63 71 0 0 1 0 2 0 0 2 5 55 0 1 0 101 COG0498(Threonine synthase) 372 312 359 361 25 36 88 118 42 30 46 56 37 115 68 95 117 136 100 154 154 145 267 134 153 225 143 144 135 23 115 238 215 159 422 523 128 611 171 141 61 88 0 0 1 3 0 2 0 2 0 57 0 1 2 136 COG0592(DNA polymerase sliding clamp subunit (PCNA homolog)) 327 305 343 343 34 27 115 122 80 36 53 78 46 134 85 73 119 151 120 144 141 164 220 144 181 263 148 160 118 32 99 203 194 162 482 536 136 543 157 126 79 75 0 0 4 0 0 1 1 0 0 41 4 2 0 106 COG2133(Glucose/sorbosone dehydrogenases) 428 363 444 376 39 39 123 82 35 29 50 52 33 158 89 82 101 139 97 117 117 137 213 124 153 137 129 148 111 29 105 215 225 170 444 428 104 686 113 198 74 79 0 0 2 0 2 0 0 0 1 78 1 1 0 156 COG0124(Histidyl-tRNA synthetase) 362 365 393 345 25 36 105 117 52 36 37 65 49 122 61 77 136 150 81 122 142 117 250 137 126 216 115 128 114 46 127 222 185 129 409 514 172 649 150 180 90 103 3 2 1 0 0 1 0 0 2 60 2 4 0 122 COG5002(Signal transduction histidine kinase) 1693 256 210 211 29 36 57 65 29 32 39 40 14 95 49 36 132 110 77 86 72 90 129 86 70 240 109 83 62 19 69 106 101 59 257 306 416 1279 88 100 28 45 0 0 0 0 2 0 1 0 2 45 0 0 0 74 COG0715(ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components) 1802 174 226 222 39 55 58 69 36 39 53 45 30 107 58 59 118 89 70 108 97 91 185 123 115 270 121 85 80 24 71 162 109 120 291 371 124 838 106 137 45 58 0 0 1 0 0 0 2 0 0 46 0 0 0 94 COG0201(Preprotein translocase subunit SecY) 309 382 366 322 34 30 134 100 47 50 41 52 41 125 70 70 121 121 106 129 162 137 291 124 133 304 121 107 113 52 120 250 204 177 408 529 132 614 126 127 76 67 4 0 1 1 0 0 1 0 0 66 0 0 0 117 COG0346(Lactoylglutathione lyase and related lyases) 952 306 322 296 23 43 85 132 54 52 46 49 45 163 88 60 94 88 116 118 108 124 219 117 114 161 100 108 77 41 86 207 166 117 389 464 97 859 122 143 53 57 4 0 1 0 0 0 0 2 0 40 0 0 0 105 COG3046(Uncharacterized protein related to deoxyribodipyrimidine photolyase) 381 340 331 382 23 31 151 109 80 36 59 63 29 84 89 68 125 106 110 122 130 144 245 167 159 258 153 160 170 42 89 240 227 171 518 320 71 565 161 140 100 61 4 0 0 0 0 2 1 0 2 79 0 0 0 115 COG0216(Protein chain release factor A) 423 320 372 362 35 35 114 121 53 56 57 51 60 138 77 63 135 124 108 107 152 150 218 125 157 223 104 121 111 39 109 200 158 135 475 529 145 675 104 141 71 69 0 1 1 0 1 0 1 1 0 74 2 1 0 107 COG0316(Uncharacterized conserved protein) 411 344 367 317 21 39 112 145 53 58 81 62 59 107 75 86 101 133 88 146 138 130 233 142 120 240 119 100 112 41 102 214 218 164 419 485 90 652 149 163 72 70 0 2 1 0 1 2 2 1 0 85 0 1 2 133 COG0128(5-enolpyruvylshikimate-3-phosphate synthase) 338 376 345 341 31 40 104 103 43 49 47 57 27 83 83 79 126 129 89 95 131 140 285 168 135 265 138 159 111 40 117 209 188 170 444 527 114 632 128 164 89 64 6 0 1 0 0 4 0 0 0 71 2 1 0 108 COG0148(Enolase) 333 259 379 306 28 40 106 86 52 19 18 66 39 110 76 86 117 155 98 153 142 135 262 139 179 338 134 172 141 61 121 226 203 137 378 449 130 638 153 147 87 70 0 0 2 1 0 1 0 0 6 86 0 0 0 114 COG1506(Dipeptidyl aminopeptidases/acylaminoacyl-peptidases) 914 328 555 236 47 31 64 57 55 32 37 59 41 127 76 58 50 61 103 82 126 135 240 134 103 264 111 123 100 54 88 225 179 113 447 325 69 703 128 158 88 54 0 4 1 0 2 1 2 0 0 78 0 4 0 96 COG0263(Glutamate 5-kinase) 437 304 256 313 20 36 121 108 45 46 59 88 40 89 73 75 121 154 107 104 144 120 248 139 153 247 115 159 152 30 118 210 154 126 400 404 107 1002 126 136 58 39 0 3 0 1 0 0 3 0 0 82 0 0 0 95 COG0192(S-adenosylmethionine synthetase) 374 379 346 336 28 38 105 116 56 62 42 79 51 125 72 78 101 113 93 119 146 139 225 170 135 208 141 128 107 36 126 254 213 149 412 531 140 577 116 156 82 69 0 0 0 2 2 0 0 0 0 55 0 0 2 125 COG0126(3-phosphoglycerate kinase) 357 332 364 341 44 34 102 87 54 61 52 80 40 88 82 87 131 148 79 114 132 143 223 162 115 235 110 137 123 43 100 191 175 174 462 538 169 609 127 154 79 66 0 1 1 0 0 0 3 2 1 75 0 0 2 121 COG0151(Phosphoribosylamine-glycine ligase) 403 319 347 304 33 31 115 124 59 43 53 80 34 98 82 52 123 124 103 130 130 145 256 152 157 107 131 129 130 51 92 198 185 154 415 485 132 765 143 187 97 53 2 0 0 0 2 0 1 0 0 62 0 0 0 113 COG1158(Transcription termination factor) 323 371 387 355 38 39 120 89 55 54 41 76 55 88 88 77 145 128 94 119 137 123 218 136 130 227 109 134 120 22 81 245 205 142 478 583 142 489 138 155 94 74 0 1 0 0 0 0 2 2 0 70 0 0 0 110 COG0260(Leucyl aminopeptidase) 491 263 320 307 28 36 96 117 52 47 58 45 52 113 69 86 170 138 83 133 145 142 263 108 140 289 134 124 126 45 102 210 195 113 392 466 133 640 162 145 65 61 2 0 2 2 0 0 0 0 0 69 3 0 3 121 COG1071(Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit) 367 190 359 260 51 44 97 98 44 48 56 49 56 129 43 66 79 103 93 107 142 144 272 149 133 186 135 140 98 64 97 230 186 121 404 462 99 951 144 244 80 93 0 0 0 0 0 2 1 1 2 54 1 1 0 130 COG0766(UDP-N-acetylglucosamine enolpyruvyl transferase) 405 316 314 322 24 29 106 90 46 46 30 71 31 122 70 81 186 154 93 125 161 123 231 129 125 285 118 133 146 24 141 230 185 126 460 488 122 617 119 190 60 69 0 2 2 0 0 0 0 0 0 47 0 0 4 104 COG1008(NADH:ubiquinone oxidoreductase subunit 4 (chain M)) 441 273 300 295 24 41 88 72 30 34 16 57 19 130 89 65 146 129 87 162 176 144 296 190 154 319 115 176 160 64 163 192 190 172 336 482 84 421 203 137 87 55 0 2 3 0 0 0 2 1 0 71 3 0 2 191 COG0042(tRNA-dihydrouridine synthase) 541 325 294 279 36 48 100 96 67 61 60 48 60 113 56 67 121 118 110 94 142 128 243 128 146 237 120 107 111 60 104 229 163 136 435 429 148 717 155 154 53 44 0 0 0 0 0 0 1 3 0 64 2 0 0 107 COG1228(Imidazolonepropionase and related amidohydrolases) 692 302 770 255 52 9 76 54 81 42 68 72 65 200 73 76 75 71 103 142 68 114 261 124 88 261 121 95 68 50 66 198 176 128 497 449 52 348 102 179 75 74 2 1 0 1 0 0 0 0 0 69 0 2 0 87 COG2225(Malate synthase) 535 424 343 422 23 29 120 135 44 59 24 56 29 113 95 78 104 85 98 141 112 120 248 139 108 73 137 135 145 5 140 257 218 149 498 533 97 391 112 138 62 80 0 0 0 0 0 0 0 0 0 66 3 1 2 107 COG0776(Bacterial nucleoid DNA-binding protein) 494 293 309 353 27 35 120 124 40 49 64 75 47 116 66 71 129 109 92 131 124 97 219 130 121 225 150 120 122 24 124 184 188 145 493 521 133 573 124 150 72 49 0 1 0 0 1 0 1 0 0 70 1 1 4 122 COG1845(Heme/copper-type cytochrome/quinol oxidase, subunit 3) 613 340 410 376 35 30 134 106 50 37 29 61 41 104 75 77 118 135 86 142 135 139 224 141 148 192 98 130 104 32 93 219 192 142 415 477 74 424 145 163 88 62 0 0 0 2 4 0 0 0 0 67 3 2 0 116 COG0012(Predicted GTPase, probable translation factor) 363 315 393 351 24 42 131 108 32 61 39 66 53 112 63 81 137 127 84 128 135 124 251 150 120 251 116 155 115 38 115 209 217 116 448 479 145 505 137 152 78 86 2 1 1 0 0 0 0 0 0 64 1 0 0 100 COG0031(Cysteine synthase) 463 289 363 304 52 50 118 108 49 63 48 43 28 92 58 65 114 130 82 129 146 148 223 161 152 286 92 124 127 40 115 214 158 125 418 453 95 650 152 192 64 55 0 0 0 0 0 4 0 0 0 54 0 0 0 109 COG0022(Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit) 343 173 344 250 51 51 116 74 58 33 40 45 40 118 58 65 94 83 104 96 175 148 274 148 139 159 136 142 112 47 98 197 206 127 381 491 85 1033 150 196 80 75 0 0 0 0 0 2 0 0 0 51 2 2 0 110 COG0079(Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase) 513 322 338 356 31 42 95 135 42 59 44 71 41 124 100 64 99 110 104 115 120 101 245 130 128 179 108 109 139 55 120 217 182 139 381 483 121 675 132 121 48 71 0 0 2 0 0 2 4 0 0 66 4 0 0 99 COG0795(Predicted permeases) 433 279 350 367 61 35 103 133 42 38 82 49 28 90 77 80 97 64 97 85 148 119 262 136 146 83 123 133 149 48 127 217 158 149 506 586 126 517 148 176 70 92 0 1 2 2 2 0 0 0 0 52 1 2 0 109 COG0728(Uncharacterized membrane protein, putative virulence factor) 466 337 318 377 28 27 96 105 48 43 24 42 41 54 62 95 153 148 100 123 114 111 234 140 154 232 118 96 144 19 115 218 168 162 443 495 147 658 138 108 56 61 0 0 0 2 0 2 1 0 0 43 0 6 3 101 COG1138(Cytochrome c biogenesis factor) 329 449 397 415 15 32 95 125 55 33 45 57 36 84 87 105 91 75 83 154 176 99 243 151 147 136 110 121 131 34 96 219 238 136 484 581 90 370 139 144 77 69 0 1 2 0 0 0 2 1 0 64 0 0 1 132 COG0206(Cell division GTPase) 302 288 344 261 31 32 91 99 47 48 23 74 62 145 73 71 105 139 78 160 150 144 265 146 162 217 128 105 132 38 100 236 235 169 409 450 206 499 103 164 76 92 0 0 2 0 0 0 0 1 4 72 0 5 0 150 COG1290(Cytochrome b subunit of the bc complex) 378 320 351 386 26 48 108 82 30 54 28 52 55 121 73 81 116 141 95 177 173 118 259 144 162 239 115 108 122 48 117 235 205 144 370 427 77 541 130 142 74 61 0 0 2 0 0 2 2 2 2 66 2 1 0 114 COG1475(Predicted transcriptional regulators) 939 321 310 309 20 21 111 102 44 30 62 41 39 123 68 60 108 132 91 134 101 99 192 93 94 270 97 95 85 24 107 175 164 134 393 473 146 609 104 116 70 52 2 2 1 0 0 0 1 0 2 61 1 0 0 84 COG3706(Response regulator containing a CheY-like receiver domain and a GGDEF domain) 2822 258 182 123 23 16 52 48 25 26 33 30 45 124 28 38 68 91 46 50 51 67 89 47 39 143 81 55 64 39 46 65 65 41 108 166 275 1157 43 36 17 19 0 0 0 0 0 0 2 1 0 14 1 0 0 48 COG0172(Seryl-tRNA synthetase) 322 275 309 294 28 37 114 80 56 68 44 63 42 69 85 70 131 124 88 148 149 106 233 154 143 280 135 172 126 38 63 185 189 144 450 525 148 547 137 152 84 65 1 0 1 2 0 0 0 2 0 90 0 0 0 137 COG4252(Predicted transmembrane sensor domain) 1505 220 262 159 24 35 53 144 39 53 80 48 39 150 78 51 71 71 98 91 77 118 200 103 104 131 116 94 70 81 70 171 123 69 302 244 203 927 94 109 38 58 0 0 0 0 0 3 0 4 0 66 1 0 0 50 COG0367(Asparagine synthase (glutamine-hydrolyzing)) 451 242 349 300 41 43 90 132 57 43 39 73 39 103 102 81 117 112 102 154 185 105 292 116 140 163 133 114 120 37 90 198 183 170 324 557 212 416 148 166 79 72 0 2 0 0 0 4 2 1 2 67 0 0 4 120 COG1282(NAD/NADP transhydrogenase beta subunit) 410 364 381 333 11 33 95 92 39 61 31 48 36 125 81 93 97 96 92 119 168 135 272 133 162 148 124 130 130 43 98 242 183 148 422 444 84 539 154 120 83 91 0 0 2 2 0 0 2 2 2 62 0 0 0 121 COG4992(Ornithine/acetylornithine aminotransferase) 416 297 309 314 46 48 91 118 59 70 36 50 61 109 71 71 122 145 73 147 115 122 225 152 135 229 112 110 104 31 117 244 223 133 420 478 124 586 111 165 67 69 0 0 0 2 0 1 0 1 0 65 0 1 0 86 COG2113(ABC-type proline/glycine betaine transport systems, periplasmic components) 766 374 308 394 13 32 103 132 55 68 27 76 59 66 76 110 85 98 83 164 93 63 154 101 112 49 116 106 70 2 58 208 188 189 468 699 97 460 136 140 57 65 0 0 4 0 0 1 0 4 2 58 0 2 0 87 COG0066(3-isopropylmalate dehydratase small subunit) 641 316 276 318 32 30 119 97 41 43 33 59 45 150 73 87 120 89 99 144 129 115 200 123 145 184 131 126 92 27 106 211 203 114 372 418 95 618 226 143 65 60 0 1 2 2 0 3 1 2 2 66 0 0 3 80 COG0010(Arginase/agmatinase/formimionoglutamate hydrolase, arginase family) 482 280 298 292 21 36 67 116 67 36 45 69 41 124 75 86 108 110 77 160 142 130 202 166 111 135 131 97 117 30 109 249 206 157 505 674 116 284 165 187 70 96 0 1 0 0 0 0 0 0 2 83 0 0 0 121 COG2390(Transcriptional regulator, contains sigma factor-related N-terminal domain) 1085 225 237 247 29 24 72 114 74 74 37 49 72 155 103 89 119 130 121 139 105 93 150 94 103 246 128 92 79 18 79 183 133 127 346 424 85 675 112 129 47 77 1 1 0 0 3 1 0 0 0 31 0 1 0 99 COG2230(Cyclopropane fatty acid synthase and related methyltransferases) 550 410 325 413 18 48 92 88 42 34 27 63 27 68 86 81 101 87 102 115 129 124 211 137 127 109 138 95 135 21 115 219 231 166 498 516 81 402 130 153 92 76 3 0 0 0 2 0 0 1 2 64 1 0 1 100 COG0519(GMP synthase, PP-ATPase domain/subunit) 341 342 341 305 37 28 91 119 39 60 34 42 32 100 68 57 155 164 91 123 140 116 209 130 162 295 123 139 128 42 95 202 188 147 406 411 116 605 149 191 59 59 0 0 3 5 0 0 1 2 0 57 0 0 0 96 COG0847(DNA polymerase III, epsilon subunit and related 3-5 exonucleases) 461 271 318 268 72 27 97 124 41 38 56 62 55 106 66 67 129 132 72 94 119 103 198 102 110 263 100 112 102 52 102 191 167 119 371 434 122 896 117 162 82 60 1 1 0 1 0 0 0 0 2 50 0 1 0 102 COG4147(Predicted symporter) 570 372 277 300 23 24 111 102 56 82 50 67 64 170 48 123 99 81 76 161 105 111 176 144 99 80 123 153 125 13 103 209 157 131 381 439 135 734 91 123 64 50 2 0 1 0 1 0 4 0 0 63 0 0 2 115 COG0777(Acetyl-CoA carboxylase beta subunit) 602 272 339 294 23 39 116 117 68 45 43 45 53 95 75 84 93 66 70 121 144 119 208 131 138 130 105 135 116 54 114 208 189 151 446 455 75 608 104 150 80 75 0 2 2 2 2 0 0 1 4 65 1 3 0 110 COG0001(Glutamate-1-semialdehyde aminotransferase) 1463 200 311 251 34 49 45 68 26 27 34 33 26 128 49 42 155 196 76 80 118 94 169 113 122 507 64 56 89 41 94 149 151 78 283 334 90 521 80 113 56 47 0 0 0 0 0 0 0 0 0 50 0 0 0 74 COG0569(K+ transport systems, NAD-binding component) 313 359 340 297 33 33 97 92 40 56 38 61 29 118 70 63 70 124 71 121 130 124 202 140 122 179 106 140 102 29 77 220 192 144 442 474 106 838 119 165 79 53 0 2 1 0 1 2 0 0 0 58 1 0 2 110 COG0770(UDP-N-acetylmuramyl pentapeptide synthase) 419 255 289 330 29 31 93 104 43 43 44 76 28 84 91 63 139 169 79 132 134 98 220 149 125 250 145 140 97 24 92 198 164 136 407 493 135 652 123 134 65 70 0 2 0 0 0 0 0 1 2 61 0 0 0 118 COG1220(ATP-dependent protease HslVU (ClpYQ), ATPase subunit) 436 309 261 295 42 32 122 123 45 47 41 97 47 68 78 96 69 107 81 159 124 91 186 127 137 113 113 122 94 16 108 175 185 157 436 481 121 799 111 150 83 105 0 1 1 0 4 0 0 3 0 53 2 0 0 122 COG0064(Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)) 341 339 370 329 13 41 112 99 57 27 43 50 29 121 75 74 150 109 98 118 130 90 231 141 149 314 110 130 92 37 106 199 159 146 412 462 132 572 175 117 74 45 0 0 0 0 0 3 0 1 0 59 0 1 0 93 COG1473(Metal-dependent amidase/aminoacylase/carboxypeptidase) 729 276 400 274 26 41 77 69 44 41 41 34 53 213 85 92 95 87 118 111 131 124 233 116 135 161 116 88 119 43 89 223 186 175 440 471 37 300 142 217 74 84 1 2 0 0 0 2 0 0 0 51 0 0 4 95 COG0533(Metal-dependent proteases with possible chaperone activity) 323 318 361 308 35 31 91 107 42 50 34 61 43 98 56 58 116 106 88 125 138 133 218 127 131 214 115 144 113 53 138 230 181 126 463 475 157 540 125 150 76 81 0 5 0 2 1 0 1 1 0 71 1 0 0 98 COG0807(GTP cyclohydrolase II) 472 270 229 247 41 32 97 113 46 81 34 61 29 84 66 63 92 114 92 106 118 131 192 123 169 244 125 117 117 36 105 197 169 161 418 435 127 776 118 168 64 86 0 0 0 0 2 0 2 0 2 72 0 0 2 102 COG0074(Succinyl-CoA synthetase, alpha subunit) 520 359 323 333 29 34 110 99 36 55 38 70 39 110 46 71 111 85 92 127 130 121 189 100 107 212 89 112 100 17 94 221 205 114 452 568 106 447 157 136 90 85 0 2 0 0 6 0 0 3 0 62 1 0 0 103 COG0014(Gamma-glutamyl phosphate reductase) 475 339 265 330 23 35 125 103 37 44 52 74 35 88 83 75 104 115 91 110 164 116 244 129 162 208 101 143 150 48 113 207 162 108 388 401 98 631 114 137 62 54 0 0 0 2 0 0 2 0 0 76 0 1 0 89 COG0538(Isocitrate dehydrogenases) 348 341 308 312 34 29 124 90 38 39 34 72 29 69 60 65 123 147 73 112 121 119 206 137 128 212 112 183 124 14 110 201 210 179 372 469 74 688 121 171 88 48 0 1 0 1 0 1 2 2 0 55 0 2 0 115 COG0376(Catalase (peroxidase I)) 470 435 406 357 26 39 104 114 35 51 44 42 72 154 34 37 89 137 65 125 106 120 234 148 147 113 116 106 123 20 115 221 206 118 397 501 52 475 89 133 54 68 2 0 1 0 0 4 1 0 2 94 0 4 2 85 COG0171(NAD synthase) 327 227 252 256 19 24 72 108 38 33 35 45 46 77 58 68 123 163 81 142 120 140 242 126 142 329 113 136 142 52 98 197 177 152 330 404 111 934 139 120 56 66 0 0 0 0 1 2 0 0 2 54 0 1 0 112 COG0162(Tyrosyl-tRNA synthetase) 410 283 358 334 33 30 89 75 48 36 34 46 30 96 78 71 122 129 70 101 129 109 244 124 148 244 99 144 134 38 100 188 182 118 411 510 135 531 115 150 69 64 0 1 0 0 2 0 0 0 2 95 0 2 2 112 COG1077(Actin-like ATPase involved in cell morphogenesis) 390 334 281 279 20 27 102 91 48 53 37 46 28 94 64 84 138 147 81 133 115 131 229 132 132 285 144 123 130 47 124 220 216 118 378 499 117 385 140 171 98 65 0 4 0 0 0 1 2 0 0 58 0 0 0 130 COG1622(Heme/copper-type cytochrome/quinol oxidases, subunit 2) 1078 266 263 282 23 24 97 90 23 38 29 59 54 94 46 58 92 108 54 120 103 91 204 152 96 209 121 101 116 41 91 182 145 158 385 417 88 514 119 105 65 61 2 1 1 0 0 1 0 0 0 64 2 1 0 122 COG0223(Methionyl-tRNA formyltransferase) 362 329 368 302 28 26 109 92 46 47 38 65 25 118 64 75 114 121 76 96 128 116 242 139 144 196 101 118 121 35 94 178 167 122 471 471 113 602 118 185 54 49 2 1 3 0 0 0 1 3 0 46 0 1 1 110 COG0750(Predicted membrane-associated Zn-dependent proteases 1) 352 332 377 359 30 30 97 108 36 35 56 54 33 101 101 71 117 124 67 131 128 120 216 124 157 233 134 100 114 43 86 188 199 122 394 434 111 528 144 137 64 50 0 3 0 2 0 2 0 0 0 82 0 0 0 105 COG1172(Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components) 1412 272 231 261 9 29 112 81 55 36 31 48 37 89 49 56 66 62 72 84 112 80 160 111 107 146 81 112 66 8 90 147 122 97 357 381 125 799 99 110 35 61 0 0 0 0 0 1 2 0 3 47 0 0 0 73 COG0470(ATPase involved in DNA replication) 203 170 215 191 25 28 62 177 41 51 99 73 56 78 62 54 151 208 84 130 153 148 301 135 178 467 109 111 146 119 123 188 190 138 237 382 134 520 123 119 92 69 0 0 2 0 0 1 0 0 0 80 1 0 0 173 COG0469(Pyruvate kinase) 525 242 309 220 34 38 63 84 36 31 38 32 35 133 57 54 116 156 71 125 127 110 214 140 146 230 110 123 137 45 83 180 153 123 312 350 130 906 128 132 76 74 0 0 0 2 0 1 0 0 0 49 0 0 0 112 COG1974(SOS-response transcriptional repressors (RecA-mediated autopeptidases)) 459 359 314 342 25 35 102 105 30 38 37 41 28 48 61 62 93 91 85 83 146 109 248 159 147 187 106 124 123 27 104 204 185 129 472 497 129 442 127 123 72 77 2 0 0 1 2 1 0 0 0 73 1 0 1 132 COG2885(Outer membrane protein and related peptidoglycan-associated (lipo)proteins) 1040 208 217 197 37 21 83 87 24 39 51 53 62 143 55 70 77 85 98 103 82 108 144 98 92 92 141 110 92 31 48 254 223 153 348 404 128 634 106 196 87 83 2 0 0 1 0 3 0 0 0 43 0 0 1 124 COG1129(ABC-type sugar transport system, ATPase component) 1558 225 215 246 11 34 70 73 60 28 29 48 35 66 55 37 78 86 66 63 86 73 140 89 106 195 98 94 64 13 57 133 103 129 312 418 91 855 92 111 30 70 0 0 2 2 0 0 0 2 6 44 2 0 0 67 COG0815(Apolipoprotein N-acyltransferase) 408 301 329 301 33 36 81 94 45 53 25 57 20 54 62 63 100 113 101 114 142 102 216 132 159 187 125 96 108 36 97 221 180 140 428 503 85 647 123 142 78 64 0 0 0 0 0 0 0 0 2 50 1 1 1 96 COG4591(ABC-type transport system, involved in lipoprotein release, permease component) 438 289 388 278 40 34 116 102 56 46 49 64 36 93 67 58 77 57 79 137 73 119 203 119 139 89 129 127 117 28 81 219 191 155 414 588 109 477 111 187 68 85 0 1 0 0 1 0 0 0 0 68 0 0 0 149 COG0229(Conserved domain frequently associated with peptide methionine sulfoxide reductase) 378 341 328 332 35 30 110 72 41 24 27 48 21 86 45 68 77 72 64 124 132 133 239 126 122 137 137 124 121 62 106 217 214 142 449 439 76 586 132 187 65 72 0 0 0 1 0 0 0 1 0 75 0 0 2 104 COG0823(Periplasmic component of the Tol biopolymer transport system) 609 331 421 341 35 24 81 103 37 40 46 53 29 78 72 77 84 69 88 100 129 114 180 125 129 109 115 131 84 22 65 202 196 132 393 436 119 545 128 138 60 69 0 2 2 2 0 3 0 0 0 62 0 1 0 99 COG0281(Malic enzyme) 747 264 208 262 32 26 68 111 48 53 51 74 56 93 72 74 159 159 90 111 86 104 171 104 96 213 111 96 82 22 68 193 179 122 439 493 113 476 131 154 70 52 0 2 0 0 0 0 2 3 0 63 0 0 0 104 COG2200(FOG: EAL domain) 4486 193 111 54 6 10 7 22 2 4 33 18 6 78 18 24 36 91 40 16 24 19 53 22 52 127 45 11 26 34 21 26 14 9 38 43 222 391 14 15 7 4 0 0 1 0 0 0 0 2 0 4 0 1 0 5 COG0366(Glycosidases) 908 174 135 134 66 42 45 70 21 14 54 22 25 78 45 45 166 265 79 70 108 83 214 111 132 483 101 93 119 81 91 103 101 97 170 163 90 1296 139 60 48 49 0 0 0 0 0 0 0 0 0 24 0 2 0 67 COG1181(D-alanine-D-alanine ligase and related ATP-grasp enzymes) 308 220 317 263 32 35 71 125 47 54 48 45 28 81 75 79 181 193 93 92 122 91 189 94 127 274 134 111 81 40 81 164 150 106 391 386 134 891 123 128 77 42 0 0 3 1 0 2 0 1 0 40 0 1 0 102 COG0082(Chorismate synthase) 316 312 309 313 23 28 103 83 41 65 31 57 53 90 81 79 104 131 82 117 144 96 227 141 143 175 120 114 99 38 98 222 186 127 422 513 103 517 145 122 74 56 0 0 2 1 0 1 0 0 0 64 1 3 0 99 COG1226(Kef-type K+ transport systems, predicted NAD-binding component) 839 172 323 218 83 111 63 54 28 32 38 25 27 124 44 52 84 55 94 86 81 74 157 104 93 78 114 83 77 150 71 136 134 109 170 205 134 1484 135 97 59 39 0 0 0 0 0 0 0 0 0 35 0 1 0 98 COG0479(Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit) 332 355 362 276 33 30 104 95 45 46 25 49 38 115 52 87 85 93 82 105 122 126 195 106 147 220 142 132 133 28 90 220 203 133 369 403 85 514 150 175 92 66 0 2 0 1 0 0 1 0 0 55 0 2 0 132 COG0755(ABC-type transport system involved in cytochrome c biogenesis, permease component) 438 339 323 324 26 26 80 97 40 49 36 59 26 90 77 100 120 115 87 112 161 112 220 136 155 202 104 121 104 28 106 195 181 134 404 480 83 419 121 119 69 50 0 0 0 0 0 0 2 0 0 61 2 1 2 94 COG0512(Anthranilate/para-aminobenzoate synthases component II) 471 292 250 355 29 21 91 104 64 64 34 53 41 92 57 78 107 113 76 107 117 116 187 130 150 174 107 110 88 43 99 181 165 116 413 466 59 720 105 128 54 51 0 1 0 1 0 1 0 1 4 54 2 0 0 88 COG1840(ABC-type Fe3+ transport system, periplasmic component) 771 280 256 275 15 26 61 88 37 41 20 32 56 69 52 56 72 95 74 143 124 102 235 141 125 91 103 139 82 31 96 193 214 156 472 489 114 435 118 126 73 72 0 1 0 4 2 0 2 2 0 77 0 4 1 76 COG0789(Predicted transcriptional regulators) 1595 147 169 130 24 13 51 37 34 24 50 39 25 110 63 65 165 150 82 68 84 54 109 76 70 322 98 75 91 8 73 98 105 95 230 306 71 993 73 104 48 60 0 0 0 0 0 0 0 0 0 32 1 1 2 92 COG2124(Cytochrome P450) 453 182 309 188 40 36 73 46 54 36 29 28 47 189 79 103 95 122 188 144 122 140 204 121 138 487 142 122 82 35 81 177 144 94 254 475 54 564 134 125 58 41 0 1 0 0 0 0 0 0 0 47 1 2 6 119 COG0136(Aspartate-semialdehyde dehydrogenase) 332 339 268 307 24 34 93 78 47 42 37 51 37 74 68 67 115 131 76 137 113 107 236 122 124 241 104 109 113 22 95 179 222 143 408 513 120 514 119 148 69 68 1 2 0 1 0 0 0 0 0 47 0 2 0 102 COG0460(Homoserine dehydrogenase) 470 290 255 298 30 36 83 92 37 49 37 57 34 84 74 77 114 140 79 97 146 99 189 132 151 246 110 138 91 36 120 167 159 128 336 404 68 696 124 117 66 43 0 1 0 2 1 0 4 0 0 62 1 3 0 117 COG1309(Transcriptional regulator) 2736 174 158 105 19 18 36 76 43 29 59 42 53 130 56 42 70 81 72 40 40 47 77 37 55 170 65 39 54 26 26 83 68 40 167 159 115 837 51 59 25 26 0 0 0 0 0 0 0 0 0 31 0 0 2 44 COG0541(Signal recognition particle GTPase) 308 284 281 351 30 45 83 78 43 84 33 58 30 158 50 63 139 122 95 124 101 91 214 124 103 237 107 112 94 27 112 219 168 158 331 438 122 618 121 133 66 52 0 4 0 0 0 5 0 0 0 55 0 0 0 104 COG0016(Phenylalanyl-tRNA synthetase alpha subunit) 313 314 340 289 36 21 105 91 31 50 25 52 27 87 53 70 109 137 87 123 142 114 197 126 149 209 121 116 121 36 97 209 190 156 408 444 143 480 157 124 57 58 0 1 0 0 0 0 1 1 0 57 0 0 0 101 COG2214(DnaJ-class molecular chaperone) 435 253 232 262 30 37 71 88 47 45 52 47 48 86 38 58 105 100 100 93 124 92 236 122 152 248 132 99 98 50 83 173 137 133 323 353 104 882 185 144 62 50 0 0 0 0 2 0 1 1 0 74 0 3 0 80 COG0685(5,10-methylenetetrahydrofolate reductase) 542 239 323 230 26 29 58 87 36 39 39 55 24 107 54 71 121 101 98 102 95 88 159 91 106 294 68 77 70 32 61 122 124 77 233 386 115 1381 97 111 30 59 0 0 0 0 0 0 0 1 0 49 2 0 2 57 COG0180(Tryptophanyl-tRNA synthetase) 412 300 301 302 29 29 93 67 61 46 36 36 44 63 60 91 125 123 64 137 105 100 226 120 101 216 109 119 104 36 90 196 171 127 393 444 147 523 123 170 68 76 0 0 1 0 0 2 1 1 0 60 0 0 2 85 COG0341(Preprotein translocase subunit SecF) 445 283 334 273 54 37 106 96 43 48 46 30 31 92 47 56 94 98 84 119 148 105 244 117 132 202 99 131 119 36 90 190 149 122 367 401 107 575 142 153 58 62 0 0 0 0 0 3 0 1 0 65 4 0 0 83 COG0824(Predicted thioesterase) 573 272 262 271 18 33 87 88 45 38 28 43 33 123 55 63 89 91 73 105 128 85 234 138 124 172 101 137 131 38 128 205 197 142 432 401 96 444 124 172 58 79 1 1 0 0 0 0 0 1 0 68 0 1 0 92 COG0859(ADP-heptose:LPS heptosyltransferase) 768 286 373 327 33 38 91 83 30 47 33 57 39 79 64 55 113 96 68 101 128 144 182 126 106 143 107 104 97 10 86 169 178 108 364 472 125 395 121 124 53 52 0 1 1 0 0 1 0 0 0 49 2 0 0 90 COG0123(Deacetylases, including yeast histone deacetylase and acetoin utilization protein) 507 255 223 293 21 32 100 81 37 43 34 48 26 84 77 77 115 96 81 121 92 102 181 103 138 147 128 120 116 28 100 240 208 161 421 405 71 613 122 139 75 65 2 0 1 1 0 0 1 2 0 53 0 0 0 130 COG0251(Putative translation initiation inhibitor, yjgF family) 857 221 291 253 26 44 80 84 41 41 27 52 49 148 78 74 84 88 82 115 124 105 178 106 96 208 98 101 101 49 70 174 192 89 377 417 66 500 107 132 57 71 1 0 0 0 1 1 0 1 2 58 2 0 2 89 COG0544(FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)) 299 290 280 305 32 24 82 85 57 41 42 58 50 147 60 84 119 125 77 99 152 123 203 123 143 221 124 115 125 38 115 192 161 119 398 397 118 476 133 151 70 71 0 1 4 0 0 2 0 4 0 58 0 2 0 113 COG0761(Penicillin tolerance protein) 378 296 281 290 16 37 83 112 36 40 40 67 41 84 56 88 143 109 61 112 140 127 203 124 130 239 106 147 111 33 107 164 169 132 320 424 46 679 104 143 74 52 0 0 1 0 0 0 2 0 0 51 1 3 0 102 COG0224(F0F1-type ATP synthase, gamma subunit) 327 322 323 277 33 31 101 85 51 63 46 59 52 118 71 75 128 115 77 106 104 112 188 141 142 229 118 130 120 27 82 225 179 141 419 433 113 392 122 127 68 68 0 2 0 0 2 1 0 0 0 63 0 0 0 88 COG0287(Prephenate dehydrogenase) 384 312 284 302 20 38 88 117 61 41 37 69 24 110 65 81 97 101 71 96 139 90 228 119 120 183 120 94 98 52 112 177 153 108 387 387 84 698 121 146 63 67 2 0 1 0 0 0 3 0 0 51 0 1 0 93 COG0536(Predicted GTPase) 315 291 348 301 26 33 109 86 38 54 26 51 45 95 64 44 110 129 76 123 103 95 226 112 125 245 99 130 125 30 102 206 172 127 358 419 81 671 137 123 47 56 0 1 0 0 0 0 1 1 0 57 0 0 0 77 COG0169(Shikimate 5-dehydrogenase) 563 266 251 292 26 27 86 94 38 41 31 52 21 93 57 54 127 135 79 100 86 101 204 142 126 208 110 112 111 25 93 187 148 125 385 384 121 659 108 137 51 56 2 0 0 0 0 0 0 0 0 49 0 1 0 93 COG0863(DNA modification methylase) 406 202 219 210 8 22 84 199 32 53 71 42 29 76 80 52 125 89 109 114 108 106 226 152 157 225 109 153 118 101 96 166 163 162 299 454 134 529 98 123 70 84 4 0 0 3 0 1 1 0 0 69 0 0 0 109 COG0047(Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain) 666 286 355 254 30 21 98 102 37 51 30 43 38 111 48 68 97 102 67 114 120 134 213 129 136 96 91 116 93 39 84 195 137 103 308 367 88 688 85 159 53 53 0 0 2 0 0 1 3 0 0 60 0 0 0 71 COG0740(Protease subunit of ATP-dependent Clp proteases) 285 213 215 253 44 28 74 110 86 29 35 48 39 99 54 76 158 136 84 119 143 128 220 143 175 398 87 114 137 71 144 204 132 90 265 337 104 648 144 112 67 51 0 1 1 0 0 0 0 2 0 66 0 1 2 70 COG0339(Zn-dependent oligopeptidases) 681 236 272 242 40 34 73 63 35 45 46 58 27 131 55 93 109 153 102 93 110 124 192 122 155 238 93 103 113 60 117 193 167 108 337 347 103 398 129 126 55 57 0 0 1 2 0 1 0 2 0 74 0 2 0 124 COG2217(Cation transport ATPase) 1558 104 97 93 23 22 21 17 2 5 13 11 5 74 27 50 189 148 58 46 81 64 121 64 81 375 95 54 54 66 56 94 81 49 46 107 125 1707 82 50 36 33 2 2 0 2 1 0 0 0 0 28 2 0 2 101 COG0114(Fumarase) 295 341 362 334 41 26 106 77 44 46 38 44 44 86 56 56 56 57 71 135 140 122 213 159 129 42 100 155 146 40 100 240 171 151 484 527 83 321 107 159 57 79 0 0 0 0 0 0 0 0 2 94 0 0 0 84 COG0612(Predicted Zn-dependent peptidases) 701 199 324 174 49 34 51 76 48 40 62 38 52 133 62 41 123 103 93 87 105 104 162 93 134 300 87 84 109 61 68 150 112 95 232 333 152 874 120 110 41 37 0 0 3 0 0 0 2 0 0 67 1 0 0 78 COG1902(NADH:flavin oxidoreductases, Old Yellow Enzyme family) 1280 203 277 212 27 39 59 80 46 58 41 36 38 212 73 72 71 89 130 91 67 101 155 133 86 168 137 92 86 28 68 159 123 91 317 311 52 468 83 126 63 33 0 0 0 0 0 0 0 0 2 39 0 0 0 80 COG0452(Phosphopantothenoylcysteine synthetase/decarboxylase) 311 257 226 305 20 26 108 64 47 38 38 46 30 99 50 98 99 106 88 97 147 98 190 113 126 163 123 127 116 23 128 158 174 151 441 480 123 542 138 161 63 61 1 0 4 0 0 2 0 1 2 61 0 1 0 108 COG0537(Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases) 395 232 291 281 22 29 92 137 47 48 41 68 36 75 68 78 138 174 60 92 111 109 164 105 143 257 123 97 104 24 79 162 176 149 358 371 146 587 135 121 70 49 0 2 1 1 1 0 0 0 0 37 0 0 0 91 COG0167(Dihydroorotate dehydrogenase) 336 317 304 300 34 28 68 88 49 35 45 44 36 100 74 43 115 117 85 108 111 120 181 130 129 230 97 100 106 30 98 169 164 130 355 424 135 584 108 146 73 67 0 0 0 0 0 0 1 1 0 74 0 0 2 77 COG1074(ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)) 581 135 210 159 53 26 55 58 67 49 63 43 29 164 67 56 116 109 91 93 107 103 175 100 74 197 81 88 76 60 79 145 129 62 309 307 141 1216 123 162 35 35 0 0 0 0 0 0 4 0 0 45 0 0 0 90 COG0462(Phosphoribosylpyrophosphate synthetase) 262 270 312 272 23 28 90 118 50 42 27 37 49 135 70 83 87 124 82 138 117 98 230 111 119 224 104 106 77 37 97 184 170 133 384 482 129 491 115 126 58 74 0 3 3 3 1 0 1 2 0 61 0 0 0 98 COG0202(DNA-directed RNA polymerase, alpha subunit/40 kD subunit) 287 284 274 298 34 30 93 103 53 48 43 61 35 77 68 75 113 131 97 115 98 120 213 113 114 229 97 95 99 32 87 193 192 93 380 383 136 548 113 166 83 50 0 1 0 0 0 0 0 2 0 87 0 1 0 88 COG1186(Protein chain release factor B) 462 266 277 290 45 34 81 85 37 36 27 34 28 56 41 89 118 123 68 105 112 106 180 132 89 236 90 101 102 33 105 217 154 116 378 419 110 553 136 172 68 61 0 1 1 1 1 3 0 2 0 57 1 1 0 91 COG0133(Tryptophan synthase beta chain) 346 324 286 318 19 35 92 96 48 52 38 48 41 102 75 48 110 128 96 123 127 71 195 129 130 176 95 96 108 34 114 208 168 116 406 429 106 520 110 113 68 37 0 0 1 0 0 2 0 1 0 60 0 0 0 83 COG0109(Polyprenyltransferase (cytochrome oxidase assembly factor)) 339 308 305 326 30 18 100 99 29 43 39 56 38 80 95 69 84 101 88 112 98 130 193 130 127 182 126 93 109 45 100 180 147 148 388 402 74 446 131 152 75 77 0 0 0 1 0 0 0 2 0 69 2 2 0 128 COG0059(Ketol-acid reductoisomerase) 395 331 255 296 28 25 107 101 43 52 25 42 51 127 76 63 113 118 89 135 119 105 212 111 143 186 92 127 103 40 85 210 163 114 375 431 80 397 131 106 79 49 2 1 0 0 1 0 1 1 0 74 0 0 0 101 COG0108(3,4-dihydroxy-2-butanone 4-phosphate synthase) 499 257 237 228 33 26 86 91 43 65 22 56 26 79 59 53 102 98 69 103 119 117 173 121 141 236 108 99 101 31 103 180 156 139 362 375 83 657 118 132 73 82 0 0 0 0 1 0 2 0 2 63 0 0 2 98 COG0726(Predicted xylanase/chitin deacetylase) 776 278 303 347 26 30 65 106 39 32 39 39 20 92 56 80 101 105 86 96 117 74 162 77 103 135 104 99 118 11 111 146 178 127 398 561 145 229 121 98 51 62 0 0 0 0 0 0 0 0 0 57 0 1 0 87 COG0771(UDP-N-acetylmuramoylalanine-D-glutamate ligase) 374 193 241 266 41 37 75 85 51 38 43 65 23 82 70 60 99 135 65 107 100 115 194 101 157 220 119 119 89 32 112 191 131 141 361 467 99 673 94 154 66 56 0 0 0 0 0 0 0 2 6 55 0 1 0 77 COG0166(Glucose-6-phosphate isomerase) 345 235 294 282 42 31 93 106 53 44 39 71 33 64 58 55 111 133 61 92 125 122 176 124 108 188 99 135 104 29 102 172 153 135 375 429 145 552 123 130 75 60 2 0 0 0 0 0 2 0 2 49 0 0 0 98 COG0540(Aspartate carbamoyltransferase, catalytic chain) 381 293 299 278 13 30 91 90 32 35 32 43 25 77 83 64 115 130 73 85 136 108 202 148 117 210 110 116 93 40 81 183 134 119 337 462 89 528 128 106 69 66 3 2 0 0 0 2 1 2 2 61 2 0 1 121 COG1322(Uncharacterized protein conserved in bacteria) 400 246 285 271 27 25 95 92 47 42 28 44 35 92 64 71 104 99 81 113 94 110 196 95 125 195 106 101 107 14 97 222 180 126 342 455 114 536 121 118 80 77 2 0 0 0 0 0 1 0 0 46 3 0 0 123 COG0482(Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain) 329 299 323 256 24 26 109 76 46 22 50 56 23 70 63 68 105 137 72 101 138 116 226 126 110 187 108 104 107 28 91 166 171 107 370 440 128 563 87 160 58 53 0 2 0 2 0 1 0 0 1 49 1 2 0 83 COG3914(Predicted O-linked N-acetylglucosamine transferase, SPINDLY family) 1312 203 280 236 36 37 47 97 41 28 10 42 43 135 77 42 78 64 62 107 123 121 184 89 118 118 78 92 102 42 91 141 144 75 258 455 107 271 108 155 43 53 0 0 0 1 0 0 0 0 0 32 0 0 0 51 COG0190(5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase) 300 294 301 339 21 27 84 70 43 51 30 51 24 136 64 75 106 96 90 106 110 123 235 112 122 211 94 107 117 36 113 195 210 103 345 409 97 406 116 127 62 70 0 0 1 2 0 1 0 4 0 79 0 0 0 109 COG0039(Malate/lactate dehydrogenases) 329 323 321 322 33 36 103 102 39 49 26 56 41 118 66 60 102 101 88 117 112 108 247 124 94 193 94 132 97 15 85 208 198 131 347 432 97 386 95 130 50 54 0 2 1 1 0 0 1 2 0 50 0 0 0 106 COG1177(ABC-type spermidine/putrescine transport system, permease component II) 1072 221 222 250 10 37 63 68 33 16 26 32 22 93 45 54 91 103 83 98 106 89 151 91 89 228 106 87 72 8 87 167 137 99 338 405 76 499 111 134 71 88 0 0 0 0 2 0 0 1 0 57 0 0 0 77 COG2239(Mg/Co/Ni transporter MgtE (contains CBS domain)) 370 298 288 290 34 25 109 64 38 39 47 77 50 82 62 66 117 99 71 109 114 92 221 128 138 198 90 106 92 39 79 182 126 83 420 414 117 573 114 114 54 41 0 0 0 0 0 0 3 1 2 36 0 0 4 80 COG0285(Folylpolyglutamate synthase) 336 225 260 255 32 27 75 106 45 30 40 63 41 102 53 69 136 120 68 120 113 110 199 102 95 238 100 93 104 33 118 211 151 107 346 474 97 561 109 121 72 65 0 1 0 0 1 0 0 0 0 50 2 0 0 112 COG0337(3-dehydroquinate synthetase) 301 272 270 265 30 44 73 106 48 31 36 61 27 82 53 38 97 117 77 104 108 143 186 127 115 213 95 118 96 27 123 171 131 114 381 406 88 643 144 144 46 57 0 0 0 0 1 2 0 0 4 45 0 2 0 103 COG0708(Exonuclease III) 334 235 317 242 35 34 79 100 51 40 31 53 35 123 77 71 68 107 90 120 115 89 188 112 129 126 94 108 81 31 80 167 163 121 408 350 106 739 104 141 70 48 0 0 0 0 0 0 0 3 2 49 0 0 0 96 COG0343(Queuine/archaeosine tRNA-ribosyltransferase) 293 289 319 269 31 29 69 97 43 69 34 50 27 90 65 77 104 105 75 114 149 143 191 138 104 254 74 112 103 45 126 180 147 127 375 405 116 374 121 137 58 65 0 1 0 0 0 1 0 1 0 55 0 0 2 104 COG0165(Argininosuccinate lyase) 435 276 228 319 22 41 80 86 32 21 27 44 22 79 69 50 116 134 75 87 114 87 165 99 124 230 126 107 108 31 97 188 156 135 336 415 132 596 104 105 58 59 0 0 0 0 0 1 0 0 3 44 1 0 0 89 COG2025(Electron transfer flavoprotein, alpha subunit) 765 289 310 252 23 18 83 83 49 36 27 52 44 114 56 65 73 103 58 115 102 114 197 100 91 188 100 89 99 14 84 177 142 111 356 460 76 315 90 128 50 81 0 0 0 1 0 0 0 0 0 51 1 2 0 118 COG0711(F0F1-type ATP synthase, subunit b) 268 261 259 295 17 25 90 84 39 42 35 75 44 88 94 81 91 111 88 105 98 121 203 143 111 177 98 101 125 31 96 199 175 104 426 430 82 535 83 144 58 57 5 0 1 0 1 0 1 0 0 60 4 0 0 87 COG0821(Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis) 333 288 295 270 27 27 87 90 33 36 44 40 40 112 68 66 105 113 79 99 126 111 194 102 155 243 131 99 90 42 93 196 158 114 345 451 60 508 107 102 47 66 0 1 0 0 0 1 0 0 0 54 0 0 0 93 COG0444(ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component) 699 198 284 224 18 48 56 100 33 19 32 37 33 150 49 43 115 104 103 95 122 113 209 108 93 306 147 130 66 12 46 126 115 115 250 336 108 582 122 107 54 42 0 1 0 2 0 0 0 0 0 37 4 0 0 132 COG0382(4-hydroxybenzoate polyprenyltransferase and related prenyltransferases) 298 268 291 297 30 36 71 86 34 40 32 34 24 69 45 58 64 71 72 124 151 131 231 123 139 96 119 125 105 51 89 204 164 132 345 387 68 712 137 123 50 54 0 0 0 1 0 0 0 0 1 47 1 0 0 85 COG0778(Nitroreductase) 482 236 305 208 36 39 88 88 64 42 33 27 37 199 60 58 80 113 102 107 109 121 168 93 78 157 97 72 103 25 58 177 141 122 355 391 117 603 96 141 48 57 4 1 1 0 0 2 0 0 0 64 1 0 2 81 COG1123(ATPase components of various ABC-type transport systems, contain duplicated ATPase) 534 222 220 254 13 58 61 69 45 29 28 43 35 126 29 56 70 94 100 78 125 104 208 132 157 250 88 134 73 31 97 211 128 127 448 426 57 331 154 194 40 68 0 0 0 0 0 0 3 0 0 58 0 0 0 64 COG0623(Enoyl-[acyl-carrier-protein] reductase (NADH)) 365 301 230 301 30 34 120 85 56 51 15 64 28 109 66 54 81 68 55 108 76 98 185 134 117 117 92 95 130 36 91 174 178 127 357 420 51 544 164 131 56 84 0 1 0 0 0 2 1 0 1 74 0 1 1 110 COG0137(Argininosuccinate synthase) 348 254 211 292 23 29 90 110 44 42 46 72 27 89 65 50 136 125 73 92 128 103 178 123 134 254 110 119 101 21 75 163 174 120 366 434 84 467 95 134 68 45 0 0 0 0 0 0 0 0 0 71 2 1 2 75 COG0744(Membrane carboxypeptidase (penicillin-binding protein)) 677 138 146 148 33 12 47 89 34 14 28 20 33 109 72 78 133 128 79 69 103 58 133 94 100 270 88 106 89 37 94 118 115 68 205 280 93 1258 115 99 50 45 0 0 1 4 1 0 0 0 0 51 4 0 2 96 COG0294(Dihydropteroate synthase and related enzymes) 292 236 260 253 19 25 112 90 40 40 33 38 25 84 61 80 86 142 57 110 151 120 208 131 126 183 101 134 101 37 105 172 147 107 312 444 106 584 120 139 57 45 0 0 2 0 0 0 0 1 0 57 0 1 0 89 COG0413(Ketopantoate hydroxymethyltransferase) 352 263 248 301 25 32 102 87 38 39 33 44 34 88 57 100 87 101 68 124 137 91 178 122 125 181 136 104 106 32 84 171 182 117 343 451 83 412 107 126 68 62 0 0 0 0 0 4 0 1 2 61 1 1 0 151 COG0196(FAD synthase) 286 259 312 291 24 34 100 94 34 46 44 55 35 69 64 62 113 115 113 81 113 117 180 122 119 185 93 102 121 26 97 165 167 133 391 467 95 377 132 117 70 71 2 0 0 2 0 0 0 0 0 59 0 0 0 100 COG0657(Esterase/lipase) 1165 191 251 185 29 33 79 106 34 48 28 38 49 141 44 65 66 42 93 105 83 76 185 92 97 161 104 116 84 26 71 170 160 104 275 314 47 436 72 138 45 61 1 1 0 4 0 0 0 0 0 47 1 1 2 82 COG0336(tRNA-(guanine-N1)-methyltransferase) 300 277 217 314 21 33 88 88 34 46 40 50 42 155 40 61 112 79 87 101 99 113 181 110 137 216 93 114 91 36 92 173 192 120 381 359 82 521 104 134 63 69 0 0 1 0 0 3 0 0 2 58 0 1 0 105 COG0009(Putative translation factor (SUA5)) 431 237 232 243 18 25 61 70 48 33 47 50 25 100 55 52 134 127 68 84 99 100 191 97 109 285 104 110 79 30 60 180 143 95 321 365 113 734 109 115 53 60 0 0 3 2 0 0 0 0 0 46 0 3 0 79 COG2079(Uncharacterized protein involved in propionate catabolism) 349 318 241 305 9 39 124 101 42 80 22 62 40 145 56 96 109 80 57 113 122 103 209 133 110 139 120 143 131 19 108 180 183 112 388 427 61 184 105 154 71 63 2 2 0 0 0 0 0 0 6 47 0 1 0 109 COG0150(Phosphoribosylaminoimidazole (AIR) synthetase) 305 228 285 266 43 27 81 131 32 38 37 53 63 72 82 61 94 78 80 92 144 107 170 103 109 99 97 114 128 94 110 165 134 117 335 416 131 573 102 142 73 57 2 0 0 3 0 0 0 0 0 67 1 0 1 71 COG0547(Anthranilate phosphoribosyltransferase) 427 246 258 292 27 21 74 104 38 51 30 30 20 82 65 76 106 111 73 107 120 93 187 119 135 193 89 119 91 31 89 167 141 88 377 348 85 628 122 115 34 49 0 0 2 0 0 2 0 2 2 45 0 1 0 85 COG1007(NADH:ubiquinone oxidoreductase subunit 2 (chain N)) 303 246 283 246 14 43 65 59 27 22 21 51 32 91 67 56 135 128 82 124 138 108 222 138 128 308 102 104 120 31 123 171 140 123 288 469 90 331 119 118 71 52 2 1 2 0 0 0 1 0 0 53 0 2 0 115 COG0417(DNA polymerase elongation subunit (family B)) 279 64 106 52 29 22 25 373 105 69 102 79 98 71 52 67 128 178 112 169 101 101 209 126 120 561 129 118 117 177 89 168 166 118 103 227 177 110 131 74 128 49 0 4 0 0 2 0 0 0 0 31 0 3 0 242 COG1121(ABC-type Mn/Zn transport systems, ATPase component) 654 181 172 217 13 28 69 73 28 33 22 36 23 117 52 28 40 60 62 100 132 107 204 123 149 156 95 111 107 50 122 170 135 101 294 263 91 780 145 114 57 74 0 0 2 0 0 0 0 1 2 59 0 0 0 106 COG1520(FOG: WD40-like repeat) 537 300 365 267 32 60 63 100 52 49 36 53 48 124 63 69 63 67 87 87 79 99 136 81 76 91 78 90 73 36 82 125 139 94 279 365 126 759 83 120 42 64 2 2 0 0 0 1 3 0 0 54 0 2 0 54 COG1061(DNA or RNA helicases of superfamily II) 227 118 114 92 27 26 32 198 63 60 93 43 53 78 47 38 116 175 107 97 94 83 226 94 115 392 117 104 114 171 62 117 139 98 140 153 82 1042 150 97 80 57 0 1 0 1 0 0 0 0 0 40 0 0 1 180 COG0331((acyl-carrier-protein) S-malonyltransferase) 1034 190 241 237 23 27 71 44 32 42 18 28 31 67 37 57 77 89 57 107 110 99 160 128 104 98 85 105 99 21 87 136 151 107 330 375 89 462 123 124 56 52 2 0 0 0 0 2 0 0 0 46 1 1 0 74 COG1396(Predicted transcriptional regulators) 1240 180 130 180 11 35 51 104 51 40 44 55 20 89 57 47 56 83 53 85 71 89 97 68 96 94 84 86 76 5 66 144 130 115 286 371 114 735 76 97 53 55 0 0 1 0 0 0 0 0 2 28 1 0 0 84 COG0501(Zn-dependent protease with chaperone function) 536 167 216 195 21 24 95 67 39 29 38 59 27 98 73 75 152 171 94 95 91 87 155 93 84 305 110 93 83 19 88 142 130 101 282 411 125 600 103 98 52 39 0 0 0 0 0 0 0 0 0 47 0 0 0 102 COG2192(Predicted carbamoyl transferase, NodU family) 302 193 190 244 4 28 55 161 37 60 57 63 47 68 52 43 87 96 90 140 109 136 210 112 129 373 111 124 120 95 87 209 187 119 265 509 114 110 114 112 77 46 2 4 0 0 0 2 2 0 0 59 2 0 0 137 COG1344(Flagellin and related hook-associated proteins) 607 183 217 185 31 101 63 112 43 54 71 16 77 161 45 45 43 44 109 79 89 112 184 145 135 80 141 111 98 49 79 197 138 100 270 193 84 716 91 122 39 62 2 0 0 2 0 0 0 3 0 49 0 0 0 116 COG0189(Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)) 396 258 264 275 27 41 87 113 31 39 45 63 21 106 71 71 82 92 77 104 108 86 206 112 92 76 102 98 109 32 78 224 168 131 301 280 175 522 104 109 56 69 4 0 0 0 0 3 1 1 4 55 0 0 0 113 COG4754(Uncharacterized conserved protein) 1279 123 119 115 11 13 60 89 21 48 32 49 27 128 34 43 91 118 55 61 51 73 101 77 80 255 89 49 31 5 46 154 111 78 233 249 127 999 84 99 37 50 0 0 0 0 1 0 0 0 0 32 0 1 0 52 COG1454(Alcohol dehydrogenase, class IV) 605 323 299 309 20 30 99 139 53 60 27 64 72 75 64 53 75 48 76 117 79 94 180 107 110 125 83 79 83 16 82 151 164 149 358 448 59 181 123 118 59 70 0 1 0 1 0 0 2 1 2 64 0 0 1 76 COG2890(Methylase of polypeptide chain release factors) 488 253 320 265 28 28 88 96 42 29 42 50 37 109 49 47 80 113 73 92 106 117 167 106 106 193 73 111 78 23 84 163 136 108 311 361 112 507 104 97 59 60 0 0 2 0 0 3 0 1 0 58 1 0 1 86 COG1089(GDP-D-mannose dehydratase) 257 161 173 205 22 29 71 125 34 25 37 59 39 66 51 58 100 134 72 110 85 95 185 113 103 349 100 137 113 76 109 153 156 110 244 487 116 552 101 101 84 60 0 1 0 0 0 1 0 0 0 46 0 0 0 134 COG1612(Uncharacterized protein required for cytochrome oxidase assembly) 336 282 300 281 40 22 85 84 42 31 30 55 28 95 85 53 110 112 81 112 91 109 163 118 108 151 112 138 121 35 78 170 140 104 359 348 60 438 114 142 65 63 0 0 0 0 0 0 0 0 0 47 0 1 0 92 COG0320(Lipoate synthase) 383 232 300 282 35 31 81 72 42 47 39 44 24 83 68 64 88 85 60 101 130 108 197 107 128 215 64 88 97 50 94 164 148 130 325 380 88 449 134 125 50 52 0 0 0 0 0 2 0 2 2 67 0 0 0 71 COG4175(ABC-type proline/glycine betaine transport system, ATPase component) 447 307 228 298 5 34 81 143 54 45 50 54 61 87 75 72 61 52 74 123 76 86 117 80 80 54 108 79 72 7 65 160 143 126 441 604 89 418 108 116 55 62 0 4 0 0 0 1 0 2 0 35 0 1 0 84 COG0024(Methionine aminopeptidase) 325 215 229 259 33 33 84 78 33 23 39 45 42 81 47 69 113 120 72 120 113 84 190 117 97 201 109 121 109 51 97 179 146 110 369 345 76 541 137 132 57 38 2 1 2 0 0 0 0 2 2 38 0 2 1 94 COG1351(Predicted alternative thymidylate synthase) 137 214 174 196 9 13 72 168 50 56 61 37 69 96 64 59 86 108 85 129 99 127 245 110 128 382 107 98 110 98 79 144 148 113 237 343 64 566 112 91 61 57 2 0 0 1 0 1 0 0 0 47 0 2 2 166 COG0857(BioD-like N-terminal domain of phosphotransacetylase) 814 193 154 169 42 20 69 101 45 49 24 54 47 79 40 60 95 92 51 83 99 80 169 92 80 148 72 82 58 31 75 124 152 74 241 299 41 928 106 161 55 39 0 4 0 0 0 0 0 1 0 56 0 0 0 58 COG0553(Superfamily II DNA/RNA helicases, SNF2 family) 433 103 221 84 52 70 59 151 62 70 105 50 97 118 65 63 127 120 181 113 73 45 90 51 76 368 100 43 41 114 38 115 84 56 94 179 105 1328 114 32 23 15 0 0 0 0 0 0 0 0 0 27 0 0 0 47 COG1176(ABC-type spermidine/putrescine transport system, permease component I) 650 257 239 266 12 32 69 92 35 25 40 32 24 85 55 51 91 83 95 100 86 92 141 87 81 215 91 82 82 9 72 166 167 148 371 460 46 291 136 147 67 74 0 0 0 2 6 0 1 0 0 53 0 0 0 96 COG1207(N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)) 333 295 253 269 14 19 80 83 31 36 28 45 46 80 62 66 105 99 66 78 104 86 193 116 107 223 118 100 82 19 108 167 165 121 292 384 120 554 115 94 56 59 0 0 0 1 0 1 1 1 0 44 0 0 1 81 COG2352(Phosphoenolpyruvate carboxylase) 480 208 163 222 26 20 88 84 37 36 27 36 26 57 56 43 100 43 53 111 116 93 212 135 144 240 113 95 124 40 105 178 137 107 298 344 80 505 157 154 71 51 0 0 0 0 0 0 0 2 0 59 0 0 4 112 COG2226(Methylase involved in ubiquinone/menaquinone biosynthesis) 289 249 263 280 29 29 85 76 44 24 35 49 30 57 56 55 89 90 85 72 103 89 195 125 111 218 89 129 103 37 97 169 166 126 318 384 90 547 102 137 53 66 0 2 2 0 1 1 0 0 0 52 0 0 1 89 COG1770(Protease II) 414 298 262 315 36 18 93 86 37 30 27 62 22 43 52 55 70 65 51 105 93 116 200 113 76 84 131 122 88 11 94 207 177 109 460 469 94 264 107 164 54 69 2 0 0 0 0 2 3 1 0 47 0 0 0 82 COG0159(Tryptophan synthase alpha chain) 328 249 224 254 12 26 75 81 34 41 47 48 42 85 54 54 81 84 70 104 135 73 178 133 128 175 80 119 104 35 92 175 127 121 404 390 77 564 113 108 70 42 0 0 3 0 0 1 0 2 0 46 0 0 0 71 COG0558(Phosphatidylglycerophosphate synthase) 262 232 270 233 18 26 76 68 22 24 23 41 23 99 52 59 112 127 54 84 123 99 167 97 105 354 115 124 133 22 76 140 141 124 356 374 96 507 116 103 54 48 0 2 2 0 0 0 0 0 0 64 0 0 0 102 COG0687(Spermidine/putrescine-binding periplasmic protein) 805 265 257 267 9 23 68 71 23 30 20 31 46 62 44 43 90 97 70 103 70 66 138 71 73 294 72 73 88 4 66 172 144 148 360 412 77 312 97 135 40 56 2 0 1 2 1 0 4 0 0 52 1 0 0 80 COG0707(UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase) 346 199 274 230 24 32 88 76 41 32 42 50 29 81 50 44 94 132 66 85 107 72 157 86 105 195 95 76 103 38 102 163 165 122 314 419 111 585 129 129 62 53 0 0 0 1 2 0 0 0 0 31 1 0 0 94 COG4771(Outer membrane receptor for ferrienterochelin and colicins) 1484 231 410 167 50 12 70 46 62 31 29 36 30 71 30 43 40 28 27 69 64 100 144 81 65 68 74 51 43 26 34 163 130 83 370 274 75 258 82 165 77 53 2 0 0 0 0 0 2 0 0 32 0 0 0 48 COG0276(Protoheme ferro-lyase (ferrochelatase)) 382 268 245 253 28 28 79 78 49 45 28 50 23 69 47 55 69 75 51 90 100 103 166 145 106 59 110 144 96 28 82 208 204 107 411 441 69 319 131 158 81 60 0 1 0 0 0 3 1 0 0 67 0 3 0 107 COG0090(Ribosomal protein L2) 215 233 288 258 16 23 97 88 26 35 26 49 43 120 72 43 112 84 54 137 105 124 178 121 116 173 116 127 102 31 99 173 158 119 311 379 77 501 108 139 60 40 2 0 1 1 0 0 2 0 0 61 0 1 0 76 COG0181(Porphobilinogen deaminase) 566 285 237 250 18 28 80 95 38 41 34 55 27 61 53 40 85 98 60 77 79 107 169 108 136 118 71 122 102 31 100 191 176 100 403 362 85 324 110 141 58 51 0 2 1 0 0 0 0 1 0 58 1 0 0 77 COG2021(Homoserine acetyltransferase) 301 290 277 308 22 23 97 103 40 39 33 65 39 76 59 68 89 112 55 111 83 93 160 111 91 177 77 92 85 13 68 167 139 130 333 517 76 407 99 102 62 74 0 0 1 0 0 1 1 1 0 52 0 1 0 83 COG0554(Glycerol kinase) 384 244 275 291 18 21 95 86 40 37 34 44 24 67 66 65 77 118 82 88 84 99 169 82 117 214 113 87 94 16 83 128 123 98 321 442 75 459 136 130 63 50 0 1 0 0 0 1 0 2 0 51 0 0 0 92 COG0356(F0F1-type ATP synthase, subunit a) 275 276 309 267 34 37 95 86 40 50 39 59 29 90 60 71 98 92 85 107 104 99 189 104 93 172 97 129 79 36 84 161 147 126 323 418 83 355 100 123 57 58 0 0 2 0 2 0 0 0 0 42 1 1 0 88 COG0242(N-formylmethionyl-tRNA deformylase) 311 224 259 234 16 24 68 87 40 45 40 46 21 85 49 45 103 102 88 91 82 101 201 98 114 240 98 96 122 57 71 179 137 83 362 357 91 525 98 153 45 53 2 1 0 0 0 0 0 1 1 33 0 1 0 90 COG0324(tRNA delta(2)-isopentenylpyrophosphate transferase) 303 280 274 277 24 25 98 77 42 32 37 55 20 88 52 61 110 81 64 110 98 95 190 114 142 176 105 120 90 35 106 175 144 99 323 374 80 436 106 100 52 37 0 6 0 0 0 2 0 0 0 55 0 0 2 79 COG0662(Mannose-6-phosphate isomerase) 570 207 261 209 24 20 75 88 35 42 46 35 21 111 65 41 70 87 55 83 88 106 170 106 122 210 94 137 101 64 111 137 107 94 314 333 70 483 94 110 51 70 2 0 0 0 3 0 0 0 0 51 0 0 2 75 COG0616(Periplasmic serine proteases (ClpP class)) 352 287 294 289 28 29 101 89 46 42 36 53 40 92 72 57 51 64 80 102 100 81 166 121 105 63 78 99 98 30 80 132 150 115 357 340 110 591 109 90 44 60 2 1 0 0 1 0 0 0 0 45 0 1 0 67 COG0266(Formamidopyrimidine-DNA glycosylase) 256 195 239 242 23 16 67 88 40 41 34 36 28 88 65 49 89 101 68 81 99 132 178 111 97 196 119 103 92 30 79 165 187 96 316 345 72 690 102 101 72 69 0 2 3 0 2 2 0 0 0 44 0 0 0 86 COG1985(Pyrimidine reductase, riboflavin biosynthesis) 255 211 183 222 24 28 63 75 31 31 42 45 9 65 65 47 108 111 58 102 150 100 193 105 133 186 98 93 84 34 86 138 131 92 349 353 95 771 115 114 56 40 0 0 0 0 0 4 1 0 2 43 0 3 0 90 COG0751(Glycyl-tRNA synthetase, beta subunit) 415 280 165 257 19 24 56 102 41 54 44 71 24 93 51 87 79 105 92 60 109 93 195 120 132 75 84 107 96 33 141 190 170 106 328 398 118 359 110 107 49 40 0 3 0 0 0 1 2 0 4 34 2 0 0 106 COG4206(Outer membrane cobalamin receptor protein) 1410 237 364 226 45 13 48 74 54 37 33 33 24 92 32 28 48 45 66 75 86 77 107 52 72 51 66 62 63 11 36 199 164 84 291 314 54 231 84 119 60 67 0 0 0 0 0 0 0 0 0 37 0 0 0 47 COG0861(Membrane protein TerC, possibly involved in tellurium resistance) 398 218 152 224 28 26 82 92 38 29 45 55 24 44 56 54 143 164 67 78 103 90 170 116 109 475 85 98 80 18 119 145 121 120 235 347 44 457 100 101 48 50 0 1 0 0 1 0 3 2 0 41 0 0 0 94 COG3958(Transketolase, C-terminal subunit) 392 204 245 194 17 16 78 94 36 57 39 42 30 98 39 43 78 91 64 83 94 91 176 88 93 243 95 69 74 22 64 120 151 93 275 385 85 803 86 121 45 47 0 0 0 1 0 2 0 0 1 41 0 0 0 84 COG1638(TRAP-type C4-dicarboxylate transport system, periplasmic component) 326 275 251 272 21 29 98 107 50 65 41 53 45 130 60 48 118 81 74 105 85 87 165 95 96 146 98 100 91 12 97 127 126 109 368 357 145 356 110 117 49 74 2 1 2 0 0 1 2 0 2 57 0 0 0 62 COG4547(Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)) 301 283 229 340 8 20 106 110 41 52 33 57 30 37 60 50 66 77 71 112 74 90 171 97 124 39 109 132 126 14 85 210 166 154 396 471 91 202 98 158 75 59 2 2 0 0 0 0 0 2 2 61 0 0 0 87 COG0249(Mismatch repair ATPase (MutS family)) 355 91 154 148 58 42 42 109 101 46 55 37 21 153 71 44 91 97 71 108 117 92 249 87 128 86 90 116 94 54 98 198 143 98 273 230 124 672 133 140 69 39 2 0 3 0 0 0 3 0 0 53 0 0 0 83 COG2089(Sialic acid synthase) 201 234 298 301 20 34 87 73 19 29 26 56 18 55 68 45 78 99 66 103 149 85 195 123 122 171 83 112 91 20 77 169 141 126 392 490 110 382 80 122 51 38 2 0 0 2 0 1 0 2 0 38 0 0 0 79 COG1879(ABC-type sugar transport system, periplasmic component) 1151 196 211 201 11 28 67 53 38 30 14 38 23 95 48 37 68 54 66 85 71 85 114 109 73 86 74 87 76 7 80 145 104 99 309 321 99 501 92 104 32 62 0 1 0 0 0 1 2 1 0 50 2 0 0 60 COG0723(Rieske Fe-S protein) 904 210 239 240 12 19 63 75 19 22 22 38 40 111 62 62 108 112 56 120 98 88 143 87 91 166 81 69 64 23 65 140 135 106 268 275 47 465 83 91 44 44 0 0 0 0 0 1 0 0 2 47 1 0 0 85 COG0107(Imidazoleglycerol-phosphate synthase) 286 258 249 283 19 29 75 81 33 48 23 66 21 63 62 59 89 109 54 86 94 86 173 111 115 162 105 113 94 27 67 159 159 118 338 396 92 430 110 122 58 63 0 2 0 2 1 2 1 0 2 64 0 0 0 78 COG0275(Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis) 288 195 272 276 27 31 84 82 30 48 43 55 21 94 35 47 100 91 69 104 117 114 209 109 120 149 82 76 76 38 71 182 136 98 396 395 100 418 114 101 49 72 2 0 0 0 0 1 0 0 1 38 0 1 0 78 COG0134(Indole-3-glycerol phosphate synthase) 321 232 233 262 31 27 74 96 34 45 32 26 19 104 42 45 147 145 72 62 95 68 173 104 91 239 96 83 83 28 81 151 104 83 306 301 91 700 85 107 42 40 2 0 2 0 0 1 2 1 0 38 1 1 0 80 COG0313(Predicted methyltransferases) 324 221 232 234 38 25 92 74 57 45 34 45 37 88 56 52 111 123 62 86 126 95 166 100 93 204 88 112 104 22 82 164 154 102 320 352 88 483 87 110 46 60 2 0 0 0 0 0 0 1 0 34 1 0 0 76 COG0407(Uroporphyrinogen-III decarboxylase) 330 237 241 294 40 31 82 76 32 38 35 34 31 88 58 49 76 78 69 92 87 73 207 137 115 78 92 107 106 36 88 159 159 111 406 406 86 267 139 126 72 83 0 0 0 0 0 2 0 1 0 60 0 1 0 76 COG0020(Undecaprenyl pyrophosphate synthase) 278 170 230 225 34 20 54 68 37 36 23 47 27 43 51 42 98 132 83 116 88 84 195 83 114 237 113 114 89 12 64 157 139 139 332 353 111 559 92 112 75 61 0 0 0 0 1 0 1 0 0 56 0 0 0 93 COG2055(Malate/L-lactate dehydrogenases) 314 256 241 302 14 33 69 88 28 55 24 93 48 111 65 80 96 115 92 133 82 81 149 105 80 78 106 115 82 12 59 159 150 130 385 459 77 216 101 126 57 66 0 0 2 1 1 1 0 3 2 46 0 0 0 97 COG0546(Predicted phosphatases) 586 216 213 237 20 32 60 100 31 65 41 51 30 106 59 55 88 68 71 79 95 92 142 93 113 94 82 80 69 31 77 169 125 119 268 305 129 615 116 96 40 31 0 0 2 1 0 2 0 0 0 28 0 0 1 51 COG0177(Predicted EndoIII-related endonuclease) 306 243 308 269 22 25 82 77 37 37 24 54 34 51 40 56 72 99 69 80 88 88 194 121 106 186 94 109 77 19 88 171 169 100 373 370 90 369 125 102 50 47 0 0 0 2 0 1 0 1 0 57 2 0 0 81 COG4091(Predicted homoserine dehydrogenase) 330 166 176 163 12 33 98 71 38 51 51 79 57 166 64 80 130 111 90 96 90 76 164 90 112 245 103 103 80 32 72 133 120 85 308 305 60 550 99 114 56 59 0 3 0 2 0 1 0 0 0 37 0 0 0 104 COG3333(Uncharacterized protein conserved in bacteria) 195 230 137 263 12 58 101 134 49 40 57 78 47 157 77 88 139 114 94 115 79 77 157 82 135 143 115 67 89 19 62 186 155 116 354 346 109 283 119 118 57 46 4 1 0 0 0 0 0 0 0 44 0 1 0 106 COG1005(NADH:ubiquinone oxidoreductase subunit 1 (chain H)) 293 209 251 245 14 15 64 63 33 32 26 51 33 60 46 56 133 154 57 89 106 96 218 125 99 345 86 116 98 35 110 172 143 116 267 425 76 267 98 81 57 30 0 0 2 0 0 0 1 0 0 57 0 0 0 104 COG1086(Predicted nucleoside-diphosphate sugar epimerases) 400 195 293 233 14 28 48 96 34 55 38 59 40 86 71 54 66 120 75 107 106 94 158 109 123 153 116 110 73 42 94 132 127 84 293 365 127 470 75 103 55 19 0 0 0 0 0 0 0 0 0 34 1 0 0 78 COG1194(A/G-specific DNA glycosylase) 269 224 267 204 25 17 79 79 44 29 36 65 22 84 49 67 93 74 87 98 90 77 168 101 110 162 93 87 103 26 68 183 174 114 332 387 71 482 124 108 50 55 0 0 4 0 0 0 0 1 2 57 1 0 0 108 COG0681(Signal peptidase I) 272 211 251 259 45 20 72 76 44 25 30 41 26 71 55 45 97 82 58 60 112 70 200 114 101 158 85 93 111 50 104 178 132 115 344 368 112 480 132 118 64 48 0 1 0 0 0 0 0 0 0 30 0 1 0 88 COG0253(Diaminopimelate epimerase) 337 232 188 240 31 25 91 57 42 60 31 50 33 127 48 58 100 109 65 96 103 89 183 114 124 118 81 106 99 27 92 168 137 97 320 394 60 463 108 111 50 51 1 7 0 0 0 0 1 1 0 29 2 0 0 90 COG1511(Predicted membrane protein) 3037 35 146 34 11 0 15 75 12 25 42 13 15 22 6 10 17 21 32 27 33 35 63 34 36 142 29 39 26 23 13 47 63 29 47 56 6 817 28 31 14 10 0 0 0 0 2 0 0 0 0 12 0 0 0 14 COG0633(Ferredoxin) 638 222 227 267 23 42 63 99 39 22 41 30 44 46 67 47 46 48 75 91 116 87 212 116 154 55 80 84 111 70 97 163 151 113 275 273 80 318 165 95 59 55 0 0 4 0 0 0 1 1 0 42 0 2 1 84 COG4770(Acetyl/propionyl-CoA carboxylase, alpha subunit) 606 189 252 197 22 47 42 98 32 49 30 31 36 111 45 49 54 99 82 84 62 74 163 75 58 167 55 74 83 12 53 134 139 79 174 314 48 868 94 90 51 75 0 0 0 1 0 0 0 0 0 66 0 0 0 68 COG0081(Ribosomal protein L1) 184 205 235 243 18 32 97 64 38 48 18 44 33 155 49 77 100 94 52 122 112 110 167 95 100 209 72 104 100 37 91 157 153 118 340 360 95 449 106 115 54 50 2 4 0 0 0 0 4 0 0 37 0 0 0 75 COG4974(Site-specific recombinase XerD) 1027 183 239 130 33 33 66 44 38 34 23 39 31 68 34 37 72 68 56 55 82 71 141 60 77 210 76 111 78 22 60 127 72 89 288 250 139 598 83 88 48 24 3 0 0 0 0 0 0 0 0 35 0 1 0 75 COG0659(Sulfate permease and related transporters (MFS superfamily)) 638 84 52 92 67 45 43 127 81 74 81 78 56 195 71 64 68 88 109 42 94 54 134 60 110 131 90 71 58 85 70 123 95 43 137 163 114 1059 120 125 36 25 0 2 1 0 2 0 0 0 0 20 0 0 0 34 COG0036(Pentose-5-phosphate-3-epimerase) 257 267 261 267 26 22 77 69 43 44 34 46 30 81 49 72 89 82 61 88 83 106 180 96 101 204 88 92 103 37 90 172 158 122 350 332 92 367 88 103 54 45 0 0 0 4 0 0 0 0 0 51 0 0 2 106 COG1410(Methionine synthase I, cobalamin-binding domain) 423 136 252 134 33 19 23 46 30 39 58 25 39 133 50 50 138 171 88 86 88 62 180 74 100 328 95 59 79 41 75 114 73 60 149 219 99 956 99 96 41 38 0 0 0 0 2 1 0 0 0 36 3 0 0 39 COG0552(Signal recognition particle GTPase) 329 220 203 232 27 22 63 90 42 31 34 38 21 143 57 51 116 116 62 89 88 90 142 94 110 181 67 115 87 29 75 142 125 123 309 354 96 517 91 107 61 73 0 2 0 0 0 0 2 1 0 27 0 0 0 81 COG2070(Dioxygenases related to 2-nitropropane dioxygenase) 726 300 317 223 40 29 93 65 49 40 18 49 40 188 43 53 45 38 79 118 72 85 201 84 89 68 97 83 74 26 75 167 131 71 313 366 70 157 76 132 40 40 0 0 0 0 0 0 1 1 0 48 1 0 0 49 COG0077(Prephenate dehydratase) 309 272 273 276 23 25 75 54 35 59 23 48 32 65 37 49 106 83 55 84 78 77 188 99 116 188 91 101 70 24 87 138 143 106 310 378 73 424 107 121 46 66 1 0 0 0 1 0 0 0 0 58 1 0 0 93 COG1686(D-alanyl-D-alanine carboxypeptidase) 456 216 228 223 10 26 67 61 35 41 35 48 32 103 39 63 90 63 64 104 82 94 164 85 91 85 99 110 87 15 58 148 145 122 375 373 88 435 132 118 47 54 0 1 0 2 2 1 0 0 2 50 0 0 0 91 COG1088(dTDP-D-glucose 4,6-dehydratase) 302 161 188 195 30 19 74 129 61 38 40 46 37 81 47 46 106 117 75 89 103 71 162 83 124 286 74 108 113 61 90 130 114 94 226 330 106 528 86 118 48 62 1 2 0 0 1 4 1 0 2 44 0 0 0 85 COG1573(Uracil-DNA glycosylase) 337 201 248 279 13 27 65 60 38 21 17 38 19 66 47 60 74 80 64 99 109 88 162 105 85 183 97 103 96 20 98 157 123 146 312 484 107 320 110 103 54 66 0 0 0 0 0 2 0 0 0 46 0 2 1 88 COG1522(Transcriptional regulators) 1081 139 180 99 19 24 31 53 53 50 56 58 39 192 95 56 43 53 78 85 57 78 115 67 66 126 79 48 60 16 43 121 104 94 219 235 159 534 67 128 57 51 0 0 0 1 1 1 0 1 0 27 0 0 0 76 COG1807(4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family) 502 238 218 262 27 36 66 63 14 17 22 34 16 51 18 36 64 94 42 63 134 114 192 121 116 138 89 91 89 38 82 220 104 78 282 257 94 560 153 77 28 26 0 0 0 0 2 1 0 0 0 53 0 0 0 91 COG0250(Transcription antiterminator) 202 194 210 229 22 21 84 85 47 44 31 38 33 154 44 61 103 94 51 106 109 89 162 76 94 224 69 97 90 35 76 157 140 104 288 311 114 579 126 86 50 38 0 3 0 0 0 0 0 0 2 46 1 1 1 74 COG0084(Mg-dependent DNase) 411 210 224 208 28 27 68 70 34 22 35 55 20 85 37 59 80 114 64 76 105 83 151 87 104 199 73 77 100 26 71 153 137 130 305 325 94 558 100 110 37 34 0 0 0 0 0 0 0 0 2 47 0 0 0 54 COG0061(Predicted sugar kinase) 244 218 223 256 22 26 58 61 30 34 22 36 31 89 44 55 105 104 48 105 132 84 190 121 119 127 76 122 98 39 83 185 137 102 305 414 78 435 94 106 59 57 0 0 0 1 0 1 1 0 0 39 1 1 0 64 COG1253(Hemolysins and related proteins containing CBS domains) 348 122 204 129 48 34 47 41 38 15 34 39 17 83 39 25 142 126 68 91 114 68 189 78 118 292 75 59 81 59 91 154 108 104 210 258 60 869 106 105 53 32 0 0 2 0 0 0 0 0 0 28 0 0 0 61 COG0531(Amino acid transporters) 1525 76 197 77 35 14 30 20 24 15 19 14 28 69 36 40 145 159 80 70 59 68 111 41 56 572 57 45 39 43 29 81 64 36 125 167 80 466 42 49 41 25 0 0 2 0 0 0 0 0 4 25 0 0 0 57 COG1054(Predicted sulfurtransferase) 269 220 247 246 29 24 83 67 32 42 31 48 24 81 47 59 87 115 64 74 116 85 190 102 86 149 91 105 98 27 84 165 139 115 390 357 91 278 118 114 74 53 2 2 0 0 0 0 0 0 0 45 0 0 0 90 COG2721(Altronate dehydratase) 371 255 195 300 12 34 60 106 41 32 25 53 49 32 72 68 128 136 64 145 85 106 148 93 91 147 77 88 90 5 86 163 191 137 366 433 63 35 77 135 55 49 0 1 1 4 3 0 0 0 0 39 0 0 0 103 COG0176(Transaldolase) 248 172 138 183 20 24 51 83 40 32 22 28 29 100 54 38 95 92 41 77 117 86 231 92 130 227 97 84 141 119 91 123 119 109 290 300 116 455 121 114 66 55 0 2 0 3 1 2 1 0 0 45 1 0 0 141 COG3959(Transketolase, N-terminal subunit) 472 186 246 189 12 8 70 82 24 44 35 35 29 78 41 45 72 100 49 60 87 76 165 73 69 222 71 54 54 15 53 115 126 93 245 318 104 881 76 104 42 27 0 0 0 0 0 0 0 0 2 28 0 0 0 67 COG0117(Pyrimidine deaminase) 250 226 198 192 23 24 58 90 27 33 49 39 11 55 54 40 94 92 57 107 133 96 177 96 125 153 96 91 78 17 76 123 127 98 326 365 82 605 101 112 59 44 0 0 0 0 0 4 1 0 2 41 0 1 0 93 COG0240(Glycerol-3-phosphate dehydrogenase) 282 281 281 239 29 14 59 91 39 59 29 41 14 109 43 46 121 125 69 95 81 81 143 86 78 155 65 74 79 17 62 164 136 78 322 369 89 448 111 107 51 42 2 3 2 0 0 4 0 0 2 32 0 1 0 85 COG0682(Prolipoprotein diacylglyceryltransferase) 285 237 247 227 29 40 86 75 31 38 46 45 17 87 37 36 73 78 74 90 86 79 161 105 95 179 91 98 93 33 84 134 134 115 331 354 79 455 81 126 51 57 0 0 0 0 0 0 0 1 0 45 0 0 1 75 COG2334(Putative homoserine kinase type II (protein kinase fold)) 384 213 224 215 10 24 56 79 26 32 37 55 24 59 32 53 99 65 68 92 100 108 122 67 92 111 91 106 75 15 67 162 157 152 302 434 93 348 132 149 58 63 0 2 2 0 0 1 0 0 0 60 2 0 2 86 COG2086(Electron transfer flavoprotein, beta subunit) 526 240 280 229 16 23 82 69 30 47 26 28 32 83 40 48 52 78 45 99 81 86 166 97 81 165 71 99 95 10 65 174 120 112 333 391 65 235 72 125 54 65 0 0 0 0 0 1 0 0 0 57 0 3 0 101 COG0791(Cell wall-associated hydrolases (invasion-associated proteins)) 403 152 182 192 20 24 42 65 29 29 43 41 27 67 45 48 132 136 70 97 109 81 150 65 117 312 83 74 85 44 80 151 129 69 247 295 63 566 101 128 38 58 0 2 0 0 0 0 0 0 0 22 1 1 0 68 COG0686(Alanine dehydrogenase) 343 237 224 215 18 17 66 98 50 36 26 53 34 93 66 71 87 107 66 131 74 78 133 91 89 175 73 112 82 18 70 165 140 128 278 385 74 315 114 79 49 63 0 2 0 0 0 3 0 0 0 65 0 0 2 84 COG1995(Pyridoxal phosphate biosynthesis protein) 324 219 228 276 36 40 68 88 48 34 37 51 43 50 65 25 64 49 73 99 103 70 156 108 109 76 72 96 87 37 99 182 133 115 363 389 87 306 121 110 49 46 0 0 0 0 0 2 0 0 0 56 1 0 0 87 COG1560(Lauroyl/myristoyl acyltransferase) 320 271 280 219 25 24 70 80 33 30 49 33 28 54 49 54 73 80 67 81 73 77 148 92 100 148 97 91 91 24 76 155 132 116 366 331 74 395 101 130 61 52 0 0 0 0 1 0 0 2 0 33 0 0 2 77 COG0471(Di- and tricarboxylate transporters) 423 264 476 200 35 26 59 77 41 47 45 32 33 138 43 36 33 22 64 89 84 116 189 82 125 17 78 79 102 48 92 160 126 94 298 254 57 413 94 117 44 37 0 0 0 0 0 2 2 0 0 36 0 2 0 32 COG0092(Ribosomal protein S3) 181 251 232 221 22 19 85 63 31 40 33 51 39 103 40 53 98 74 47 113 102 89 184 122 105 196 76 95 86 29 71 151 140 88 284 304 94 510 101 108 53 52 0 0 0 1 1 0 0 0 0 50 0 0 0 68 COG2759(Formyltetrahydrofolate synthetase) 270 323 279 287 18 21 68 110 42 43 29 60 51 109 56 57 77 64 62 96 104 104 135 98 80 104 93 78 79 16 64 142 132 117 308 436 74 216 98 117 48 74 0 0 0 0 0 0 1 2 0 41 2 0 0 70 COG4251(Bacteriophytochrome (light-regulated signal transduction histidine kinase)) 3069 152 66 65 10 9 24 18 4 15 33 16 6 56 14 22 71 76 29 16 14 25 39 28 23 147 55 29 27 23 19 21 19 9 33 48 151 413 18 17 8 6 0 0 0 0 0 0 0 1 0 4 0 0 0 6 COG0101(Pseudouridylate synthase) 231 228 265 220 15 28 86 70 35 38 20 47 42 73 53 49 96 104 61 68 102 83 171 93 103 181 81 102 103 31 75 180 142 104 302 347 72 401 92 115 44 47 2 0 1 0 0 0 2 1 2 40 1 0 0 101 COG1595(DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog) 880 115 154 85 43 15 52 47 37 21 59 36 33 128 59 45 117 99 77 57 52 45 102 38 68 228 82 56 43 26 51 88 104 63 213 227 146 864 47 95 34 40 0 0 1 0 3 0 0 2 0 28 1 0 1 34 COG0548(Acetylglutamate kinase) 381 219 186 253 25 23 73 84 30 42 51 72 19 70 58 65 127 113 61 64 78 63 148 101 90 180 87 54 85 30 56 138 107 92 256 332 95 585 89 73 37 41 0 0 0 0 0 0 0 0 0 36 0 0 0 70 COG0071(Molecular chaperone (small heat shock protein)) 390 174 194 167 18 19 68 67 25 38 53 38 34 77 30 50 62 66 40 100 93 95 173 106 104 215 77 94 114 91 67 155 130 100 303 325 93 361 130 112 55 53 0 1 1 2 1 0 0 1 0 61 0 1 0 110 COG1104(Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes) 372 157 206 164 20 26 56 43 30 26 23 33 42 84 55 47 101 116 67 60 138 103 190 108 112 279 79 86 94 70 76 114 107 76 209 231 80 724 95 84 39 21 1 0 0 0 0 0 0 2 0 32 4 3 0 48 COG0152(Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase) 314 244 250 238 29 20 72 98 33 50 50 47 35 77 54 53 83 89 55 102 86 84 177 102 125 84 88 91 78 28 72 141 130 85 336 332 76 371 91 107 46 60 0 1 0 0 0 1 2 1 0 72 0 2 0 68 COG2804(Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB) 1018 184 300 168 16 26 39 76 13 40 30 42 33 76 49 28 68 58 60 72 60 75 125 93 58 140 93 81 68 20 58 88 73 42 198 221 246 578 30 67 17 21 0 0 0 0 0 0 0 0 0 31 0 2 0 49 COG0264(Translation elongation factor Ts) 224 195 239 191 18 27 75 59 30 31 32 41 24 77 56 56 86 107 56 59 86 94 158 94 144 173 115 98 83 26 83 187 133 117 324 338 119 458 102 105 39 52 0 0 0 0 0 0 1 0 0 37 0 0 1 77 COG0557(Exoribonuclease R) 360 169 176 170 48 51 70 70 43 35 61 34 24 100 60 51 118 93 65 65 100 71 147 119 121 112 81 80 83 63 63 165 121 88 303 263 66 576 130 88 54 58 0 0 0 0 0 0 0 0 0 35 1 0 2 70 COG1519(3-deoxy-D-manno-octulosonic-acid transferase) 266 254 234 243 34 26 73 98 39 35 31 46 26 66 72 38 62 52 58 89 72 61 128 94 79 82 98 109 88 19 73 173 157 133 437 401 73 296 95 119 52 85 0 0 0 0 1 0 0 0 0 62 0 0 1 92 COG0052(Ribosomal protein S2) 207 194 249 220 23 32 65 69 22 25 44 59 35 64 67 66 86 94 55 77 82 89 169 98 104 169 101 96 94 29 81 189 150 117 332 346 91 413 95 119 44 47 0 0 2 0 0 0 0 0 0 30 0 0 2 80 COG0025(NhaP-type Na+/H+ and K+/H+ antiporters) 507 199 222 198 30 23 48 65 26 34 38 53 27 112 47 32 34 73 55 64 116 96 124 90 105 133 70 92 68 40 72 156 117 90 311 315 104 555 100 115 41 22 0 4 3 0 1 0 0 0 0 22 0 0 2 67 COG0078(Ornithine carbamoyltransferase) 272 219 227 235 22 20 62 76 25 44 25 35 30 93 49 55 111 101 44 55 84 115 171 118 88 164 111 98 81 23 87 166 139 94 274 383 65 451 72 95 60 42 0 0 0 0 0 1 1 0 0 46 0 2 2 76 COG1146(Ferredoxin) 340 256 273 280 14 24 75 100 38 40 42 39 37 85 41 55 79 55 46 99 63 85 117 67 77 153 115 80 70 10 55 168 144 120 299 396 86 340 92 123 54 37 0 2 0 0 0 1 0 0 0 41 2 1 1 89 COG0595(Predicted hydrolase of the metallo-beta-lactamase superfamily) 217 177 148 265 24 29 64 80 32 32 29 39 24 52 49 60 104 139 57 81 102 83 183 96 100 185 48 113 96 21 93 147 158 92 279 329 125 538 116 90 43 43 0 0 0 0 0 1 0 0 0 49 0 2 2 66 COG5285(Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin) 346 253 320 280 25 47 41 112 35 28 22 35 22 98 80 64 55 44 86 107 98 89 200 98 83 62 87 102 59 16 45 153 115 94 298 568 46 151 118 107 49 36 0 0 0 0 0 2 0 0 0 33 0 0 0 75 COG2513(PEP phosphonomutase and related enzymes) 553 249 255 256 11 14 70 103 31 49 28 48 40 78 59 63 95 78 72 85 83 100 141 101 94 124 105 80 92 16 87 154 146 76 301 370 88 96 69 89 46 53 2 3 0 0 0 0 0 0 5 54 0 0 0 69 COG0087(Ribosomal protein L3) 225 240 232 185 24 24 76 62 39 40 24 47 48 116 46 57 85 105 59 97 102 96 174 96 114 176 89 97 98 14 64 172 118 102 268 285 120 401 99 105 46 53 3 0 0 0 0 0 0 0 0 50 3 2 0 88 COG0118(Glutamine amidotransferase) 301 231 235 221 21 26 77 86 27 36 40 54 31 64 48 70 73 97 52 83 97 85 160 95 91 161 73 94 82 25 72 127 130 97 337 372 94 369 97 118 38 57 0 0 1 0 0 2 0 0 0 44 0 0 2 68 COG0812(UDP-N-acetylmuramate dehydrogenase) 246 182 221 241 23 33 70 67 35 36 32 37 19 65 45 44 97 137 52 60 105 92 171 85 105 181 72 90 84 29 71 147 135 118 352 335 83 452 88 95 61 33 2 0 4 2 0 2 1 0 2 48 0 0 0 73 COG0303(Molybdopterin biosynthesis enzyme) 528 158 212 155 8 34 31 79 24 31 44 33 32 73 60 47 90 107 70 93 62 62 121 68 69 198 90 72 40 2 37 119 105 108 305 318 86 678 96 98 42 53 0 2 1 0 2 0 0 0 2 35 1 0 0 74 COG0852(NADH:ubiquinone oxidoreductase 27 kD subunit) 216 158 221 228 8 16 58 51 25 19 14 34 36 134 60 61 113 109 57 85 104 120 178 100 112 317 82 113 76 22 102 139 119 100 211 361 46 441 75 59 48 48 0 0 0 0 0 0 2 0 0 52 1 0 0 120 COG1905(NADH:ubiquinone oxidoreductase 24 kD subunit) 263 192 188 225 5 17 63 87 24 33 19 32 20 88 47 69 103 115 65 115 77 98 118 99 71 218 82 71 79 6 73 129 121 119 348 383 102 445 98 94 57 51 4 2 0 0 0 0 0 0 0 32 0 0 2 101 COG0461(Orotate phosphoribosyltransferase) 247 237 255 219 22 28 56 68 33 13 34 33 20 74 53 38 85 126 45 64 106 84 169 79 106 172 76 92 84 59 67 157 114 85 336 327 67 434 94 132 57 65 2 0 1 1 1 0 2 0 1 54 0 0 0 73 COG0299(Folate-dependent phosphoribosylglycinamide formyltransferase PurN) 315 178 259 196 28 27 63 101 17 62 39 43 34 75 89 39 74 74 68 94 97 90 153 79 89 84 88 75 85 43 68 130 130 113 285 345 86 525 83 119 52 43 0 2 0 1 0 0 0 0 0 30 1 0 3 72 COG1190(Lysyl-tRNA synthetase (class II)) 359 215 287 181 35 16 59 48 43 40 26 25 19 81 34 62 103 135 59 71 110 52 175 97 120 243 85 105 79 43 60 132 107 59 193 264 112 542 88 106 47 31 2 0 0 2 0 1 0 2 2 35 0 0 0 53 COG0140(Phosphoribosyl-ATP pyrophosphohydrolase) 381 181 180 196 27 21 69 124 37 42 18 47 12 77 59 63 91 101 57 84 68 71 128 92 76 88 94 95 63 24 76 134 147 98 328 336 75 562 103 85 52 40 0 0 2 0 2 0 0 0 2 48 0 1 1 86 COG0302(GTP cyclohydrolase I) 277 251 227 229 35 22 72 76 35 27 39 39 30 61 53 59 56 123 46 91 77 72 158 110 90 164 71 106 89 45 80 148 132 112 315 335 76 406 74 105 45 45 0 0 1 0 0 0 0 2 0 45 0 0 0 91 COG0284(Orotidine-5-phosphate decarboxylase) 241 216 230 227 21 22 62 87 30 28 29 58 32 62 39 39 96 90 56 85 107 75 186 101 111 178 84 103 101 27 83 141 131 94 308 353 86 361 84 126 55 39 0 1 1 0 0 0 0 0 0 52 0 1 1 88 COG1082(Sugar phosphate isomerases/epimerases) 440 211 217 208 11 50 86 57 49 31 38 38 32 85 79 45 63 74 77 87 82 66 131 83 88 95 109 113 60 12 69 126 87 108 285 284 121 546 61 121 38 50 0 0 0 0 0 2 0 5 0 45 0 0 2 61 COG1212(CMP-2-keto-3-deoxyoctulosonic acid synthetase) 305 254 272 229 17 24 88 76 32 45 23 43 39 65 35 44 73 63 61 82 62 78 181 97 92 128 87 106 62 15 74 135 156 100 335 368 85 353 79 128 53 52 0 1 0 0 0 0 5 0 2 49 0 2 0 71 COG1364(N-acetylglutamate synthase (N-acetylornithine aminotransferase)) 229 211 206 266 17 21 46 77 20 43 44 72 25 51 38 52 125 115 61 84 103 78 158 85 92 146 82 78 84 15 110 122 139 90 280 342 78 522 121 68 41 45 0 0 0 0 1 1 0 0 0 38 0 0 0 88 COG1225(Peroxiredoxin) 284 186 262 210 22 25 67 49 32 15 29 28 20 115 59 42 86 107 64 70 124 110 178 106 127 232 73 104 104 48 72 132 115 74 224 280 59 475 93 84 52 42 0 0 0 1 1 0 0 0 0 52 0 0 0 74 COG0424(Nucleotide-binding protein implicated in inhibition of septum formation) 302 217 213 221 20 19 72 68 23 40 43 41 17 75 53 35 82 112 63 88 74 77 153 71 87 171 63 85 88 18 73 155 138 120 318 274 78 541 72 128 37 64 0 0 0 1 2 1 1 0 0 33 0 0 1 73 COG1884(Methylmalonyl-CoA mutase, N-terminal domain/subunit) 87 137 344 166 23 22 33 66 54 39 42 36 48 124 56 41 66 75 56 92 90 122 153 81 64 283 80 78 68 30 32 159 143 81 157 237 27 845 48 121 59 58 2 0 0 0 0 1 0 0 0 62 3 2 1 106 COG4665(TRAP-type mannitol/chloroaromatic compound transport system, small permease component) 197 261 188 251 11 21 75 130 27 43 34 57 45 95 55 82 87 102 88 116 69 78 120 91 95 82 96 93 73 8 58 167 190 108 381 409 73 167 120 104 60 60 2 2 0 1 1 0 0 0 0 57 2 0 0 64 COG0113(Delta-aminolevulinic acid dehydratase) 325 233 202 269 30 22 80 74 41 43 27 44 35 53 42 57 72 65 41 83 114 104 158 90 120 67 74 61 89 34 77 206 137 96 310 379 94 272 120 124 53 58 0 1 1 0 0 0 0 1 0 60 0 0 0 58 COG0836(Mannose-1-phosphate guanylyltransferase) 466 165 178 200 26 23 71 89 35 42 51 45 9 140 43 41 56 51 53 52 102 80 160 82 99 115 101 108 87 30 94 112 109 114 303 309 88 514 77 101 42 36 0 0 0 0 2 0 0 1 0 48 0 1 0 42 COG0763(Lipid A disaccharide synthetase) 290 217 251 273 33 33 80 76 35 32 38 32 24 45 56 47 39 68 51 88 110 85 177 104 106 86 84 99 94 39 91 179 128 105 375 369 79 279 91 95 55 53 0 0 0 0 0 0 0 2 0 45 0 1 0 53 COG3845(ABC-type uncharacterized transport systems, ATPase components) 179 151 187 164 6 18 60 24 26 17 26 29 25 114 43 43 68 93 52 95 68 113 166 90 99 194 108 106 84 9 81 167 149 118 353 395 59 419 137 148 67 78 0 1 0 0 1 0 0 0 0 56 0 0 0 103 COG1968(Uncharacterized bacitracin resistance protein) 276 243 218 213 16 23 64 73 38 36 28 42 25 58 35 52 67 87 69 70 64 92 187 98 102 163 75 97 73 18 83 150 128 119 331 350 67 422 101 85 54 66 0 1 0 0 3 1 0 0 0 41 0 1 0 73 COG0332(3-oxoacyl-[acyl-carrier-protein] synthase III) 314 185 286 152 38 30 74 56 50 21 45 49 36 87 61 46 71 83 85 76 93 83 140 93 83 82 101 100 84 32 60 138 149 79 340 301 94 482 76 135 50 38 0 1 0 0 0 0 0 0 0 35 0 0 2 60 COG0235(Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases) 653 228 178 227 26 31 56 70 27 41 23 41 27 67 57 57 74 65 64 94 72 71 136 92 77 123 72 79 57 23 67 147 131 91 295 333 90 278 92 94 42 51 0 1 0 0 0 1 0 0 0 47 0 0 0 103 COG2050(Uncharacterized protein, possibly involved in aromatic compounds catabolism) 531 224 267 229 12 20 72 66 33 36 39 27 41 116 45 67 91 54 51 77 94 73 148 84 80 82 91 84 79 14 65 109 101 95 293 347 48 396 94 86 45 51 0 2 0 0 0 0 0 0 0 35 1 2 0 73 COG0030(Dimethyladenosine transferase (rRNA methylation)) 217 171 232 233 17 25 60 83 25 20 30 35 23 39 47 45 81 63 49 87 116 82 158 88 102 186 109 97 96 33 92 149 132 103 277 368 99 418 100 118 64 42 0 0 0 0 1 3 0 1 2 50 0 0 0 97 COG0127(Xanthosine triphosphate pyrophosphatase) 275 211 248 202 23 19 62 62 31 25 35 40 24 53 47 44 70 87 50 81 129 78 177 114 92 163 74 83 96 33 68 154 127 111 345 327 75 367 113 117 50 54 2 0 3 0 1 0 0 0 0 42 0 0 0 78 COG0402(Cytosine deaminase and related metal-dependent hydrolases) 756 96 163 164 20 25 14 38 34 31 25 39 42 118 46 35 64 51 84 109 115 108 150 77 82 211 53 78 61 39 52 133 120 85 210 258 63 487 89 103 78 37 0 0 0 0 0 0 0 0 0 35 0 1 0 65 COG1160(Predicted GTPases) 235 188 251 171 27 35 60 68 28 48 41 42 26 77 47 58 91 110 52 72 86 77 169 86 93 236 76 77 76 46 81 124 107 71 302 258 73 624 80 90 43 33 1 2 0 0 0 0 2 1 2 31 0 1 2 57 COG0397(Uncharacterized conserved protein) 315 216 214 223 19 32 58 91 33 36 37 39 29 84 62 81 74 66 64 93 86 90 177 87 120 65 79 75 84 49 75 167 149 120 353 321 70 279 108 84 40 65 0 2 0 0 0 0 0 0 0 39 0 2 2 78 COG0217(Uncharacterized conserved protein) 258 234 212 218 20 24 77 87 27 37 24 54 34 80 33 53 79 117 43 104 85 75 138 69 121 161 97 78 81 12 50 138 148 86 334 396 82 367 97 99 45 45 3 0 0 2 0 0 0 0 0 42 0 0 0 57 COG1211(4-diphosphocytidyl-2-methyl-D-erithritol synthase) 262 186 215 215 15 24 71 75 32 23 16 40 19 58 43 44 102 118 48 66 109 71 167 106 112 191 66 106 97 41 77 141 139 92 287 301 75 465 99 91 38 50 0 0 0 0 0 2 0 0 0 37 0 0 0 75 COG0088(Ribosomal protein L4) 189 205 233 196 14 22 60 78 27 29 25 45 31 101 55 48 98 93 50 104 103 98 164 92 113 175 94 94 77 22 59 147 119 84 254 309 125 441 93 114 54 39 0 0 1 0 0 0 0 0 0 46 2 2 0 80 COG0563(Adenylate kinase and related kinases) 285 224 229 213 23 23 68 66 34 29 35 36 20 43 45 37 75 124 60 86 96 91 170 83 61 184 70 77 76 38 72 140 122 110 269 339 98 475 85 88 33 55 0 0 0 0 0 0 1 0 0 33 0 0 0 68 COG1385(Uncharacterized protein conserved in bacteria) 263 219 215 224 19 35 72 71 31 40 29 41 28 57 60 52 68 86 52 85 100 64 154 110 92 149 47 86 92 20 86 177 97 113 311 322 90 398 85 105 48 53 1 2 1 2 0 0 0 0 0 55 1 0 1 74 COG0149(Triosephosphate isomerase) 217 223 270 194 27 18 72 61 46 22 16 40 22 81 65 46 88 97 55 63 87 83 158 102 92 166 105 65 73 27 59 115 115 97 295 307 94 482 105 117 46 47 2 0 4 0 1 0 0 0 2 30 0 0 2 80 COG0522(Ribosomal protein S4 and related proteins) 195 211 203 224 21 16 81 77 38 21 23 49 43 55 38 53 81 84 72 79 104 81 161 97 94 172 76 88 82 29 67 151 112 104 314 286 103 411 111 95 68 62 0 1 0 0 0 0 1 0 0 49 0 1 0 96 COG3181(Uncharacterized protein conserved in bacteria) 198 139 89 150 7 31 64 87 33 31 28 47 31 92 42 59 528 339 56 81 60 45 92 56 59 637 86 50 50 12 46 126 102 82 216 203 72 209 78 72 43 38 0 0 0 0 2 0 0 0 0 38 0 1 0 61 COG0396(ABC-type transport system involved in Fe-S cluster assembly, ATPase component) 150 172 266 228 24 17 76 54 32 14 24 34 17 58 54 36 79 96 46 107 100 89 163 126 114 199 100 91 87 30 84 122 130 90 278 372 72 375 112 99 59 42 2 1 1 0 0 0 0 3 0 52 0 0 1 84 COG0325(Predicted enzyme with a TIM-barrel fold) 292 239 243 233 24 27 66 57 27 38 30 38 21 80 40 46 59 99 54 76 64 82 158 85 94 146 78 80 68 16 85 120 122 104 272 373 99 395 87 116 45 66 0 0 1 0 0 0 2 0 0 37 2 0 2 61 COG4666(TRAP-type uncharacterized transport system, fused permease components) 272 212 179 262 6 30 43 58 30 43 37 54 43 99 57 70 77 85 72 91 67 53 132 99 78 70 88 71 44 6 55 152 150 95 302 424 78 509 83 97 32 42 0 0 0 0 0 0 0 0 0 39 0 1 0 62 COG0226(ABC-type phosphate transport system, periplasmic component) 502 265 314 284 16 28 94 21 11 21 39 13 13 73 28 50 93 140 77 189 131 180 339 217 175 307 41 27 42 37 20 37 13 15 37 39 33 553 26 16 7 8 0 0 0 0 0 0 0 1 0 12 2 0 0 57 COG0629(Single-stranded DNA-binding protein) 310 186 143 188 19 23 70 80 46 28 22 22 24 52 44 44 79 87 80 73 94 87 140 105 102 160 82 56 80 29 97 136 98 86 235 290 69 724 76 74 40 39 0 1 0 0 0 0 3 0 0 53 0 0 0 67 COG0164(Ribonuclease HII) 245 171 249 183 33 26 59 80 41 24 23 38 30 53 58 55 95 106 47 82 97 81 169 100 107 143 84 94 85 22 89 133 113 98 276 390 115 335 94 89 47 67 2 2 0 2 1 4 0 0 0 35 0 0 0 70 COG1073(Hydrolases of the alpha/beta superfamily) 574 273 268 234 11 19 72 55 21 19 17 23 17 62 33 32 38 45 41 84 73 87 149 77 102 53 81 63 90 22 78 164 136 77 274 311 96 316 85 92 51 59 0 1 0 0 0 2 0 1 0 54 0 0 0 103 COG0289(Dihydrodipicolinate reductase) 261 196 180 246 4 22 65 79 28 33 41 32 25 68 42 47 97 105 67 91 80 83 164 106 110 127 64 106 86 23 79 162 126 92 309 316 78 356 103 104 49 54 2 0 0 2 0 1 0 2 0 44 1 1 0 69 COG2374(Predicted extracellular nuclease) 1031 145 308 154 29 8 10 10 18 15 9 20 16 24 10 11 5 13 20 81 125 258 302 94 80 32 147 186 70 30 40 87 76 39 53 481 49 342 25 57 19 29 0 0 0 0 8 0 1 0 0 7 1 0 0 38 COG1108(ABC-type Mn2+/Zn2+ transport systems, permease components) 268 165 152 191 19 28 56 60 17 30 17 26 20 89 55 39 30 37 52 82 97 91 180 109 129 94 79 106 95 57 84 177 122 82 249 223 78 628 142 82 40 51 0 0 1 0 1 0 0 0 4 61 0 1 0 94 COG0248(Exopolyphosphatase) 436 271 223 292 24 45 85 24 17 16 22 12 15 72 28 29 90 113 60 56 124 97 217 114 114 289 60 69 52 34 56 96 87 58 159 113 55 601 63 68 33 24 0 0 0 0 0 0 0 0 0 26 0 0 0 40 COG2220(Predicted Zn-dependent hydrolases of the beta-lactamase fold) 441 247 195 215 17 24 52 91 31 37 32 41 32 39 52 33 47 55 38 75 102 80 176 84 112 149 84 95 103 49 83 128 108 112 295 330 75 260 112 60 29 42 0 0 0 0 1 2 0 2 2 38 3 0 2 58 COG1187(16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases) 553 151 170 123 60 30 52 50 38 23 51 22 24 91 34 49 87 108 68 60 76 69 140 88 92 179 61 64 49 44 53 131 109 70 244 216 106 605 74 102 41 35 0 0 0 0 0 0 0 0 0 30 0 0 2 44 COG0805(Sec-independent protein secretion pathway component TatC) 280 210 243 250 19 27 66 68 46 38 15 38 30 55 32 39 86 65 49 78 82 82 136 86 96 155 77 97 82 23 53 116 134 96 264 333 79 406 77 104 55 60 3 0 2 2 0 0 1 0 2 47 0 0 0 80 COG2227(2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase) 205 243 216 239 24 19 57 89 28 24 36 47 19 76 46 57 74 59 65 77 99 84 164 79 84 84 60 71 81 22 74 137 121 84 309 326 70 481 105 102 47 43 1 0 0 0 4 2 0 0 0 49 0 1 2 75 COG0774(UDP-3-O-acyl-N-acetylglucosamine deacetylase) 298 227 267 275 26 31 70 77 38 35 22 40 20 65 45 23 43 77 47 71 86 58 156 82 91 68 63 81 90 40 87 178 142 123 343 312 80 249 112 97 49 56 0 0 1 0 0 0 0 0 0 36 0 0 0 83 COG0646(Methionine synthase I (cobalamin-dependent), methyltransferase domain) 335 176 236 208 16 11 25 41 39 31 45 29 42 89 45 47 90 127 68 61 83 58 115 65 62 172 85 57 71 24 54 110 79 86 180 381 97 722 70 80 26 38 0 1 2 0 2 0 0 0 0 30 0 0 0 48 COG3000(Sterol desaturase) 367 264 304 205 26 28 68 72 38 52 37 35 43 102 40 21 40 36 62 66 68 79 178 79 86 39 82 61 58 31 52 166 172 93 369 355 68 125 101 150 53 53 0 2 0 0 2 2 0 0 0 42 0 1 0 84 COG0576(Molecular chaperone GrpE (heat shock protein)) 207 217 197 179 14 22 80 63 35 19 36 38 20 57 42 54 80 91 56 99 106 98 134 97 109 143 79 119 83 31 71 124 106 95 294 318 93 412 110 97 52 47 0 2 1 0 0 0 0 1 0 38 0 1 0 82 COG1049(Aconitase B) 345 214 222 184 26 26 71 50 36 46 27 31 36 127 57 50 55 41 59 75 79 73 169 109 123 38 63 93 77 75 75 163 107 80 320 197 45 380 147 106 38 65 0 4 0 3 2 0 0 2 0 63 1 1 0 65 COG2151(Predicted metal-sulfur cluster biosynthetic enzyme) 328 159 238 170 27 35 47 57 17 25 38 30 24 66 47 53 66 85 68 82 91 70 136 81 93 237 87 63 82 32 59 132 119 76 217 302 62 494 89 125 47 34 0 1 5 0 1 1 4 0 2 50 0 1 2 75 COG0041(Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase) 266 208 222 203 23 25 59 51 19 41 38 33 31 95 54 41 85 78 70 78 93 83 155 73 118 103 74 76 64 24 56 126 125 73 285 287 80 551 86 88 38 43 0 1 1 0 0 0 0 1 1 41 0 0 1 58 COG1984(Allophanate hydrolase subunit 2) 541 211 208 217 15 33 81 85 42 25 36 50 37 95 59 63 45 46 85 81 63 56 133 86 56 87 49 68 83 10 68 112 108 77 254 408 63 300 74 89 56 45 0 0 1 0 0 0 0 0 0 48 2 3 0 49 COG0345(Pyrroline-5-carboxylate reductase) 282 229 192 235 28 20 85 68 31 30 24 41 18 74 42 50 88 65 53 75 69 90 152 89 83 126 67 79 85 14 78 147 130 102 287 329 63 428 62 73 47 44 0 0 0 2 0 0 1 0 0 42 1 2 0 70 COG0094(Ribosomal protein L5) 203 218 210 193 30 21 60 61 35 47 35 34 19 67 38 52 129 82 48 86 97 78 134 98 69 160 75 85 72 22 85 132 127 100 285 311 80 379 106 103 40 62 0 0 0 2 2 0 0 0 0 49 2 0 0 61 COG1044(UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase) 257 177 265 221 23 30 62 70 32 22 18 38 19 45 52 44 58 48 50 104 110 83 168 110 99 59 69 111 80 41 79 152 143 106 330 311 71 273 109 95 54 67 0 2 0 0 0 3 0 0 2 38 1 1 0 64 COG0145(N-methylhydantoinase A/acetone carboxylase, beta subunit) 355 163 298 203 18 52 41 47 23 48 21 22 45 215 49 43 47 15 110 109 69 87 162 76 76 102 82 59 46 16 54 140 82 75 204 279 68 434 89 143 41 42 0 0 0 0 0 0 0 0 2 40 0 0 0 72 COG1947(4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase) 226 197 207 211 19 27 56 69 33 34 21 43 35 146 41 53 64 96 51 79 61 77 158 83 99 154 83 86 95 23 85 141 93 87 246 306 72 423 117 87 39 36 2 1 0 1 1 0 0 0 0 46 0 0 0 48 COG1609(Transcriptional regulators) 1404 105 91 80 12 28 20 46 21 21 47 32 50 131 37 31 67 108 79 64 21 45 56 30 52 105 75 44 34 14 24 93 70 57 177 130 72 627 47 98 17 35 0 0 0 1 0 2 0 0 0 14 1 0 0 42 COG0193(Peptidyl-tRNA hydrolase) 230 184 216 213 16 15 72 73 28 34 32 45 35 102 44 42 90 87 75 77 76 74 175 79 77 146 66 89 73 37 52 125 110 105 258 323 89 380 98 95 39 54 0 1 3 0 0 0 0 0 0 49 0 0 1 67 COG1940(Transcriptional regulator/sugar kinase) 266 130 157 146 14 22 65 42 23 28 22 38 25 89 72 68 99 151 72 60 74 65 129 79 66 290 71 90 66 11 45 100 91 87 216 238 84 695 83 60 45 52 1 1 0 1 0 0 0 0 0 25 1 0 0 93 COG1741(Pirin-related protein) 686 162 143 223 27 34 61 50 32 29 32 31 26 32 32 45 102 98 44 78 74 69 145 92 78 134 60 92 80 20 61 108 112 77 194 225 66 417 76 103 42 41 0 0 0 0 2 0 0 0 0 36 0 2 0 68 COG1825(Ribosomal protein L25 (general stress protein Ctc)) 213 186 217 183 11 9 75 80 25 36 24 39 33 134 48 48 85 89 72 104 83 71 159 72 86 153 80 75 74 14 60 121 118 125 281 318 72 378 77 122 30 56 0 3 3 0 0 0 0 0 0 37 0 0 4 56 COG0231(Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)) 188 234 266 218 22 24 62 50 34 27 30 35 28 93 42 37 64 95 43 83 101 80 194 90 92 137 76 95 76 22 78 114 121 83 262 312 121 331 81 83 43 58 0 0 0 1 0 0 0 0 0 34 1 0 2 63 COG1846(Transcriptional regulators) 1439 89 116 151 16 18 35 46 32 12 31 32 22 88 29 43 74 65 39 55 56 32 65 50 29 93 66 57 62 6 38 118 74 51 174 211 60 477 32 91 37 35 0 0 1 0 0 0 0 0 0 27 0 1 2 42 COG2802(Uncharacterized protein, similar to the N-terminal domain of Lon protease) 378 224 246 213 12 25 62 83 17 18 25 41 18 83 44 33 70 90 38 74 104 59 122 95 110 83 97 96 81 22 66 109 100 83 254 285 50 404 96 100 37 40 0 0 2 0 2 2 0 1 2 52 1 0 0 69 COG0476(Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2) 421 183 228 227 17 34 69 59 24 21 23 36 24 73 34 48 52 97 59 64 85 83 143 108 87 141 73 95 72 44 84 123 126 100 244 280 69 284 103 86 30 37 0 0 1 2 0 0 0 1 0 44 0 0 0 77 COG0098(Ribosomal protein S5) 190 203 195 186 24 21 74 62 26 21 28 35 29 69 56 49 89 89 53 59 80 75 159 81 81 207 88 80 77 25 68 146 128 86 249 298 74 448 101 88 33 53 0 0 1 0 0 0 1 0 0 51 0 0 0 79 COG0075(Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase) 514 185 194 169 22 35 45 54 30 28 15 15 15 107 40 22 56 45 62 88 102 61 160 82 86 81 78 72 69 51 81 129 123 107 243 257 61 387 129 103 32 65 0 0 2 0 0 0 0 0 0 49 1 0 0 60 COG0283(Cytidylate kinase) 174 217 245 220 26 20 63 59 38 16 25 41 19 53 30 43 75 96 42 76 89 72 163 93 69 177 78 93 68 22 91 121 121 85 292 322 70 412 91 101 54 39 0 0 0 0 0 0 0 0 0 38 1 0 2 61 COG3347(Uncharacterized conserved protein) 767 171 159 155 10 15 32 72 22 46 21 25 32 129 66 50 59 61 55 77 71 57 139 60 71 160 61 38 53 14 47 103 78 84 267 311 33 416 67 76 25 42 0 0 0 2 1 1 2 0 0 36 1 0 2 57 COG2234(Predicted aminopeptidases) 568 138 296 108 37 20 64 62 46 33 26 39 15 91 45 66 49 52 58 63 92 113 123 54 59 139 72 65 49 31 33 143 86 56 270 282 61 392 63 127 62 64 0 0 0 3 0 0 0 0 0 29 2 0 0 47 COG1137(ABC-type (unclassified) transport system, ATPase component) 295 237 229 224 16 26 68 50 37 24 18 36 32 54 40 34 60 48 47 71 73 91 137 98 98 83 81 65 87 27 79 126 114 113 372 273 82 334 94 105 46 51 4 0 3 0 0 0 0 0 1 34 0 2 0 68 COG5616(Predicted integral membrane protein) 779 132 191 152 14 29 43 38 25 46 0 24 38 87 40 25 40 84 41 77 61 114 147 61 101 124 74 99 50 15 71 100 83 84 210 251 58 427 86 113 29 30 0 0 0 0 0 4 1 0 0 36 0 2 0 51 COG0328(Ribonuclease HI) 233 153 181 181 27 25 49 82 51 22 24 49 42 56 42 61 105 100 66 78 101 70 139 68 84 198 71 72 74 36 83 112 112 102 259 317 79 432 66 83 40 40 0 2 0 0 0 1 0 1 2 48 1 0 0 62 COG0002(Acetylglutamate semialdehyde dehydrogenase) 311 168 142 211 28 27 71 92 29 33 41 39 26 68 58 47 99 97 48 77 64 63 124 85 92 177 59 90 64 23 82 121 133 73 287 265 79 454 75 73 44 32 0 3 6 2 0 0 0 0 0 38 1 0 1 56 COG0743(1-deoxy-D-xylulose 5-phosphate reductoisomerase) 247 206 235 275 17 21 54 57 17 14 15 25 23 62 51 32 68 93 45 68 94 78 176 85 94 165 84 75 65 34 78 127 80 100 245 301 58 448 95 72 28 59 0 0 0 0 0 0 2 0 8 36 0 0 0 66 COG1278(Cold shock proteins) 290 173 193 173 18 24 57 102 36 28 40 39 35 84 55 61 102 82 72 93 59 72 103 80 76 124 61 73 60 7 58 106 116 99 221 347 90 524 74 93 35 32 1 1 0 0 0 0 0 0 0 42 0 0 0 63 COG2177(Cell division protein) 594 92 133 84 8 8 32 27 39 13 33 22 34 75 34 42 84 108 61 44 40 66 110 42 60 252 68 70 35 14 34 86 99 82 185 272 48 889 73 105 37 45 2 0 0 0 0 0 0 0 0 21 0 1 0 69 COG0794(Predicted sugar phosphate isomerase involved in capsule formation) 382 224 257 179 21 17 70 55 27 42 36 35 28 58 52 44 65 52 49 72 61 81 119 92 87 80 78 72 94 12 54 111 124 77 269 294 84 423 87 85 40 36 0 2 1 0 1 2 0 1 0 37 0 0 0 80 COG0717(Deoxycytidine deaminase) 187 197 213 193 8 32 58 111 27 27 25 42 23 62 46 47 104 80 49 69 78 71 145 85 93 163 79 61 66 29 64 136 136 93 230 285 73 528 87 75 32 33 2 3 0 1 0 0 0 0 0 30 0 0 3 62 COG0408(Coproporphyrinogen III oxidase) 265 240 191 244 21 30 82 76 38 46 37 52 21 65 68 58 57 46 36 88 87 70 119 92 94 50 82 87 85 37 88 155 157 88 271 291 50 242 107 101 61 53 1 2 0 0 0 0 0 0 0 47 0 0 0 62 COG0503(Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins) 259 196 186 244 17 29 62 46 22 23 23 26 39 62 33 36 67 52 42 84 87 97 156 90 89 118 68 71 75 19 78 154 140 99 260 274 72 442 89 108 35 44 0 1 0 0 0 0 0 0 0 40 0 0 0 76 COG2877(3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase) 295 201 216 216 23 26 71 77 29 31 32 45 29 77 35 60 69 73 52 87 73 60 139 70 76 101 65 93 80 18 64 138 120 101 255 337 68 320 88 95 49 43 0 0 0 2 2 1 0 0 2 46 0 0 0 74 COG0801(7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) 236 191 187 180 18 23 85 88 41 25 21 42 23 62 63 63 61 74 54 104 78 75 146 95 88 93 82 84 82 18 82 132 121 79 288 342 108 297 93 111 45 30 0 0 0 0 0 0 0 2 0 35 0 0 0 75 COG0353(Recombinational DNA repair protein (RecF pathway)) 172 203 228 227 24 21 66 76 24 42 22 42 23 54 45 38 81 100 66 89 52 41 140 77 88 162 63 80 94 24 71 128 134 80 309 295 73 401 74 83 43 46 0 2 0 1 0 0 0 0 0 39 1 1 0 70 COG4597(ABC-type amino acid transport system, permease component) 201 209 139 239 8 14 96 66 21 18 10 42 35 87 62 66 56 42 44 103 83 110 168 91 99 43 101 85 95 10 45 143 149 92 269 346 59 235 141 94 71 46 0 0 2 0 0 2 0 0 0 72 0 0 0 105 COG2870(ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase) 293 135 275 162 16 28 60 83 28 50 29 22 30 68 42 45 56 83 49 105 80 82 151 87 76 248 69 77 95 25 54 146 120 104 191 323 116 229 80 102 48 36 0 0 0 0 0 0 0 0 0 22 0 1 1 78 COG2770(FOG: HAMP domain) 1183 224 121 114 8 26 30 38 13 23 25 17 16 48 23 30 52 64 37 16 48 47 105 59 63 55 39 23 42 42 40 57 43 24 79 66 225 1027 27 12 21 18 0 0 0 0 0 0 0 2 0 12 0 0 0 10 COG0097(Ribosomal protein L6P/L9E) 196 235 196 185 16 25 72 47 26 26 24 30 11 64 53 50 94 79 41 58 81 67 143 89 89 162 91 93 76 23 67 115 124 98 287 292 95 367 97 90 27 68 0 0 0 0 1 0 1 0 0 58 0 0 0 63 COG2262(GTPases) 321 125 219 141 31 19 58 39 22 26 28 52 28 104 49 47 100 96 59 76 58 50 126 53 72 194 86 87 55 16 51 123 94 79 222 274 66 602 85 76 55 43 2 0 0 0 0 0 0 0 2 28 0 0 0 53 COG1853(Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family) 634 138 155 149 45 33 54 56 24 36 25 27 33 76 55 31 38 40 49 59 131 61 178 79 112 103 74 54 80 48 85 130 105 66 235 167 43 388 112 106 39 47 1 0 1 1 0 0 0 0 2 34 0 0 2 48 COG5000(Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation) 317 192 209 228 18 24 59 85 35 31 44 39 12 50 60 30 86 83 38 62 55 71 136 72 74 106 78 87 77 3 57 134 121 118 328 337 76 194 91 112 52 60 0 0 0 0 2 3 0 0 2 29 0 0 0 85 COG0307(Riboflavin synthase alpha chain) 228 180 180 173 21 19 56 65 34 25 25 47 9 68 50 47 78 85 47 80 92 78 132 94 101 136 86 89 58 39 57 149 104 90 287 281 66 422 67 85 61 39 1 0 0 0 2 1 0 0 0 34 0 1 0 88 COG0026(Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)) 245 180 149 165 20 30 49 59 26 32 29 31 20 59 47 39 91 88 72 71 89 58 139 80 88 132 79 84 72 28 73 118 140 69 280 281 56 516 99 103 35 36 0 0 0 0 0 0 1 0 0 41 0 0 0 58 COG3239(Fatty acid desaturase) 471 194 175 219 21 37 71 49 27 26 28 18 26 82 45 44 54 35 63 68 115 94 193 106 129 99 78 87 92 67 81 123 108 93 209 257 52 136 112 100 22 41 0 0 0 1 0 0 1 0 0 41 0 0 1 60 COG0232(dGTP triphosphohydrolase) 244 175 140 196 18 11 53 59 27 28 17 33 27 43 40 58 69 115 38 60 98 73 130 58 77 133 66 112 65 5 61 134 122 119 284 312 79 410 95 100 44 57 0 1 0 2 0 0 0 2 0 37 0 0 0 116 NOG22164() 116 272 395 223 30 10 88 107 59 83 38 43 59 165 87 86 5 10 118 112 58 68 145 85 87 2 41 76 120 23 65 138 121 73 253 324 38 102 63 93 41 37 0 0 1 0 0 0 2 0 0 45 0 0 0 36 COG2377(Predicted molecular chaperone distantly related to HSP70-fold metalloproteases) 274 254 216 223 17 26 74 78 39 40 38 45 34 38 44 58 57 54 39 63 64 63 123 76 58 66 73 70 64 18 60 134 132 115 354 339 55 282 77 80 63 34 0 2 0 0 0 0 0 0 0 36 0 2 1 81 COG3468(Type V secretory pathway, adhesin AidA) 1364 67 320 74 49 28 18 132 26 27 29 18 19 76 17 30 75 85 45 29 69 68 130 48 79 211 51 49 36 38 29 54 58 33 55 119 47 289 59 46 32 24 0 0 0 0 3 0 0 0 0 11 0 0 0 55 COG1466(DNA polymerase III, delta subunit) 241 225 194 229 16 20 53 73 31 13 42 28 22 60 28 39 94 80 60 65 100 50 109 77 61 149 53 70 69 21 84 133 131 82 274 297 96 377 102 97 39 37 0 2 0 0 0 0 1 0 2 32 0 0 0 62 COG2197(Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain) 1527 45 26 39 22 12 13 20 12 11 26 20 10 63 18 17 95 104 37 7 26 16 38 18 24 174 26 14 22 37 23 41 13 16 31 46 90 1330 50 18 6 8 0 0 0 0 0 0 0 0 0 14 0 0 1 9 COG0712(F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)) 205 204 219 195 17 18 61 95 33 25 24 44 37 64 31 59 65 81 39 66 83 81 124 83 85 157 75 82 84 25 64 141 109 74 282 339 60 344 88 83 32 35 2 0 0 0 0 0 3 0 0 39 0 0 0 59 COG0571(dsRNA-specific ribonuclease) 279 159 180 198 24 17 41 121 40 27 42 35 48 65 41 61 121 109 55 62 84 66 133 76 79 137 69 54 59 18 57 114 120 84 231 286 100 369 94 88 51 38 0 1 0 1 0 0 0 0 0 28 0 0 0 49 COG0244(Ribosomal protein L10) 180 168 189 219 8 21 77 49 26 36 20 36 21 132 45 56 75 65 47 96 106 92 130 84 91 159 84 70 74 28 79 130 119 102 244 271 76 352 72 93 39 45 0 2 0 0 0 0 1 0 0 36 0 0 0 62 COG1403(Restriction endonuclease) 244 191 168 214 11 23 43 49 16 24 30 39 24 58 40 25 87 93 62 52 74 86 146 81 100 217 58 77 88 38 88 144 106 92 211 265 63 409 72 68 51 41 0 1 0 1 2 1 0 0 0 32 1 1 0 82 COG0321(Lipoate-protein ligase B) 226 190 225 213 24 18 59 63 30 39 19 36 18 70 46 50 84 70 56 72 86 74 149 83 97 157 76 65 66 20 81 142 109 94 270 291 53 308 85 104 40 36 0 0 0 0 0 0 0 0 0 32 1 0 0 62 COG0464(ATPases of the AAA+ class) 625 107 193 180 56 108 32 32 17 31 26 10 15 95 65 18 55 86 42 56 84 79 113 68 54 293 79 33 61 60 54 61 54 38 60 157 95 605 74 50 44 29 0 0 0 3 0 0 0 0 0 36 1 0 0 55 COG0131(Imidazoleglycerol-phosphate dehydratase) 254 173 172 201 28 29 80 66 28 35 20 36 33 79 43 51 80 85 53 60 76 69 123 74 66 116 58 82 77 26 57 114 93 74 300 342 83 401 83 96 41 35 0 0 2 0 0 0 0 0 2 24 0 0 1 62 COG2355(Zn-dependent dipeptidase, microsomal dipeptidase homolog) 532 215 189 180 13 16 73 59 44 33 33 37 28 88 55 55 24 21 53 80 39 69 122 61 59 31 80 59 68 7 67 116 112 96 360 388 31 200 68 117 43 45 0 2 0 5 2 0 0 0 0 38 1 0 0 67 COG1651(Protein-disulfide isomerase) 258 197 208 194 7 25 47 68 20 25 27 44 23 89 40 40 66 79 58 72 62 57 122 68 64 187 60 60 51 13 56 116 107 92 279 284 110 480 73 84 28 38 0 0 0 2 0 0 0 0 2 29 1 2 1 64 COG0335(Ribosomal protein L19) 238 217 173 234 19 27 63 73 32 40 31 29 38 104 35 43 81 64 51 70 78 79 129 83 72 126 60 90 61 22 51 134 130 108 269 261 60 295 76 95 43 52 0 0 1 0 1 2 0 0 4 56 0 1 2 70 COG0608(Single-stranded DNA-specific exonuclease) 305 139 149 160 27 27 40 103 42 39 40 40 28 122 59 47 102 83 70 40 37 39 87 53 63 140 67 66 47 9 40 146 93 64 258 294 156 487 96 111 32 41 0 0 0 0 0 0 1 0 0 37 2 0 1 42 COG2907(Predicted NAD/FAD-binding protein) 369 193 177 231 9 23 45 82 36 31 21 44 31 66 46 46 69 68 55 50 66 62 155 62 102 72 79 84 71 13 73 144 124 97 266 290 68 247 110 77 37 57 0 0 0 0 0 0 1 0 2 44 0 0 0 72 COG1452(Organic solvent tolerance protein OstA) 293 200 206 204 14 26 46 78 25 26 31 23 23 66 34 40 79 59 28 85 74 58 119 79 86 60 83 75 59 11 78 136 137 90 308 342 95 333 94 99 30 40 0 1 2 0 0 0 2 0 0 32 0 0 0 57 COG3665(Uncharacterized conserved protein) 305 216 160 242 9 22 70 81 40 16 20 50 16 42 42 63 44 41 59 131 83 59 114 89 60 16 70 92 50 5 46 117 124 119 380 402 64 154 106 112 54 62 1 0 2 0 0 0 0 0 0 34 0 0 0 82 COG0855(Polyphosphate kinase) 467 280 147 298 25 26 79 13 9 9 12 13 3 66 17 13 91 108 57 51 95 107 210 111 123 295 26 30 39 32 35 65 33 19 72 73 45 819 48 19 17 22 0 0 0 0 0 0 0 0 0 21 0 0 0 22 COG2925(Exonuclease I) 264 256 195 263 10 20 68 96 27 51 30 36 26 57 47 64 56 36 47 102 75 78 124 113 86 31 62 88 68 9 65 130 146 93 283 344 58 193 74 88 52 50 2 0 0 0 0 0 0 0 0 30 1 0 0 67 COG0584(Glycerophosphoryl diester phosphodiesterase) 360 157 213 156 21 9 70 60 21 18 24 22 24 60 64 39 68 77 56 102 73 70 130 58 71 177 94 83 72 14 57 124 107 100 200 287 46 454 67 75 40 56 0 0 0 0 0 1 0 0 0 29 0 0 0 50 COG0290(Translation initiation factor 3 (IF-3)) 210 225 224 225 15 16 59 57 29 36 36 31 26 45 57 33 77 74 48 61 78 68 144 90 107 151 79 96 72 16 68 124 113 89 242 279 74 353 80 74 28 47 0 2 0 0 0 0 1 1 0 40 0 0 0 54 COG0156(7-keto-8-aminopelargonate synthetase and related enzymes) 405 131 195 113 29 42 81 45 31 33 48 21 19 75 46 38 49 51 65 80 92 81 168 71 81 103 75 56 65 37 60 113 102 72 229 218 66 409 103 162 41 57 0 0 0 0 0 1 0 0 2 33 0 1 0 58 COG4608(ABC-type oligopeptide transport system, ATPase component) 436 131 203 142 16 35 39 32 25 14 16 26 31 87 41 38 86 78 55 68 76 75 142 67 64 297 102 81 52 12 34 102 63 55 165 249 74 531 72 65 30 28 0 1 2 0 0 0 1 0 0 23 3 0 0 83 COG1354(Uncharacterized conserved protein) 253 204 192 211 9 14 50 66 23 31 25 26 21 43 35 38 86 81 41 83 83 72 148 89 77 178 72 79 60 18 53 115 100 76 237 266 52 505 81 94 33 23 0 0 0 0 0 0 0 0 0 41 2 0 0 62 COG0237(Dephospho-CoA kinase) 217 193 246 190 25 15 52 58 23 14 21 50 12 57 40 39 83 54 45 84 74 66 155 77 77 153 74 82 74 30 75 113 102 81 279 330 88 345 76 87 44 43 0 1 0 2 0 0 2 0 0 37 0 0 0 62 COG1209(dTDP-glucose pyrophosphorylase) 269 125 144 150 25 16 64 73 59 23 31 37 41 58 48 33 74 80 52 58 76 75 134 72 63 166 51 77 73 27 44 108 122 81 280 256 72 496 81 92 51 71 0 0 0 0 0 1 2 0 2 38 0 0 0 71 COG3127(Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component) 363 140 157 172 17 47 51 93 50 31 43 51 50 84 64 34 96 49 71 61 53 82 123 64 67 57 69 60 57 12 52 124 123 75 250 220 82 482 56 96 39 58 0 0 0 0 2 1 0 1 0 41 0 1 0 68 COG1218(3-Phosphoadenosine 5-phosphosulfate (PAPS) 3-phosphatase) 217 221 186 206 11 19 72 50 23 35 15 35 8 59 38 49 58 47 42 91 105 84 158 85 100 94 90 68 76 26 57 137 125 75 283 344 61 293 74 105 44 52 1 0 0 0 1 0 1 0 0 39 2 0 0 60 COG1384(Lysyl-tRNA synthetase (class I)) 183 243 174 228 11 23 66 69 30 27 27 57 17 41 77 31 69 49 44 79 58 64 119 104 112 87 84 73 82 5 63 119 145 113 284 352 92 130 88 126 65 53 0 0 0 0 0 0 0 0 0 67 0 0 2 81 COG2211(Na+/melibiose symporter and related transporters) 206 200 273 195 43 28 80 86 39 67 37 34 50 113 61 59 8 10 86 69 81 59 147 91 85 17 89 82 62 41 79 145 90 68 304 305 60 219 83 108 36 49 2 0 1 0 0 0 0 0 0 38 0 0 0 19 COG1834(N-Dimethylarginine dimethylaminohydrolase) 200 216 209 218 12 18 75 83 28 35 18 29 50 70 57 75 35 54 36 104 115 83 116 68 95 71 96 84 67 8 53 151 127 106 271 368 52 138 93 102 51 40 0 0 0 0 0 0 0 1 0 38 0 0 0 87 COG0357(Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division) 238 230 169 224 21 23 63 77 23 31 23 33 20 76 25 41 88 81 62 79 77 72 148 70 73 146 66 83 64 20 64 133 108 86 263 297 59 282 79 101 48 43 0 1 0 0 0 0 0 0 0 38 0 0 0 51 COG0194(Guanylate kinase) 217 158 170 191 24 17 49 80 40 27 25 28 27 44 33 39 49 68 40 61 93 73 127 81 83 142 88 100 83 24 71 102 98 72 287 289 70 389 103 106 52 51 0 0 0 0 1 2 2 1 0 37 0 3 0 80 COG3791(Uncharacterized conserved protein) 333 222 264 261 14 32 42 85 36 37 35 41 32 74 42 32 23 28 62 82 86 83 137 78 98 10 68 71 56 18 78 140 118 91 311 356 54 87 68 111 36 45 5 0 0 0 3 1 1 0 0 36 1 1 0 66 COG1562(Phytoene/squalene synthetase) 262 138 110 174 17 21 32 57 26 22 27 35 23 97 35 36 77 94 43 74 92 68 140 70 98 172 68 82 72 38 50 126 126 96 226 197 61 431 106 126 65 42 0 0 0 0 2 1 0 1 0 37 0 1 3 92 COG0848(Biopolymer transport protein) 569 269 219 207 15 22 64 71 27 29 36 23 23 101 45 50 63 43 49 49 56 65 100 66 86 58 75 45 54 29 40 120 112 57 303 271 53 226 73 79 30 21 0 1 0 1 0 0 2 2 0 47 0 0 0 42 COG3638(ABC-type phosphate/phosphonate transport system, ATPase component) 745 161 108 163 24 35 90 36 9 21 21 11 11 40 36 19 46 14 27 39 75 60 143 81 86 66 56 60 58 30 52 107 71 61 166 197 81 680 77 83 24 16 0 1 0 0 2 0 0 2 0 19 0 2 0 75 COG1058(Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA) 279 151 200 216 17 25 70 64 31 35 29 31 31 59 48 49 70 97 57 92 79 82 124 92 91 101 74 93 85 28 89 129 131 108 273 318 43 130 109 69 33 47 0 3 0 0 0 2 2 0 2 32 0 0 0 60 COG3588(Fructose-1,6-bisphosphate aldolase) 196 245 274 246 7 22 55 46 30 31 16 51 21 43 67 43 42 42 38 67 82 81 163 114 87 118 58 83 118 61 74 132 106 117 260 334 39 135 67 90 34 27 0 0 0 0 0 0 2 0 0 45 1 0 0 65 COG0228(Ribosomal protein S16) 180 187 176 203 21 16 79 51 12 55 20 46 36 109 38 44 74 58 46 78 82 64 122 68 98 125 75 77 50 15 69 125 120 97 241 259 66 400 99 83 34 39 0 6 0 0 0 3 1 0 2 48 0 1 0 68 COG1546(Uncharacterized protein (competence- and mitomycin-induced)) 222 109 151 183 23 20 57 57 34 28 31 36 24 86 51 40 79 94 47 108 93 72 125 80 95 134 85 84 69 30 75 134 113 74 251 300 72 323 111 88 37 44 0 0 0 0 0 0 2 0 1 39 0 0 0 53 COG1122(ABC-type cobalt transport system, ATPase component) 749 68 92 94 9 27 34 27 17 15 4 26 21 50 31 33 80 111 56 27 122 79 138 86 82 207 69 58 58 36 74 92 102 70 153 164 75 540 91 68 22 17 0 0 0 0 0 0 0 0 0 20 1 0 0 64 COG2010(Cytochrome c, mono- and diheme variants) 1115 121 122 112 8 30 39 40 13 12 19 20 15 93 21 24 77 96 41 49 44 42 105 70 58 164 56 37 32 29 38 81 55 27 123 124 53 667 49 44 11 22 0 2 1 0 0 0 0 0 0 25 0 1 1 29 COG1159(GTPase) 247 148 161 156 52 32 57 61 13 42 56 34 29 96 36 29 76 107 44 61 65 48 125 67 105 204 62 55 69 24 48 111 74 62 247 243 61 597 52 95 25 18 2 0 0 2 0 1 2 0 0 27 0 1 0 27 COG1038(Pyruvate carboxylase) 348 92 121 77 19 10 44 52 18 36 28 34 18 83 38 58 28 51 65 51 22 21 73 38 26 45 44 47 53 3 22 124 115 114 214 180 32 1296 92 89 44 30 2 0 0 0 0 0 0 0 0 25 0 1 2 20 COG0049(Ribosomal protein S7) 177 214 199 214 24 28 61 53 30 18 17 33 26 62 40 44 88 78 57 82 72 76 134 91 83 148 61 93 58 19 63 122 108 80 247 266 99 340 63 80 47 42 0 0 0 0 0 0 0 0 0 42 0 1 0 60 COG3203(Outer membrane protein (porin)) 3658 6 40 6 1 0 0 9 6 14 9 5 0 14 5 4 11 9 9 3 2 3 4 0 2 7 11 7 4 4 7 15 14 15 43 45 0 7 9 5 4 7 0 1 0 0 0 0 0 0 0 10 0 0 0 3 COG1216(Predicted glycosyltransferases) 529 95 211 121 25 17 27 52 29 19 16 29 18 60 34 21 122 134 42 49 46 41 98 49 65 271 36 55 39 14 58 84 66 51 171 191 98 727 40 67 28 21 0 0 0 2 1 0 0 0 0 27 0 0 0 38 COG0110(Acetyltransferase (isoleucine patch superfamily)) 404 155 210 144 13 32 67 70 21 8 22 26 21 54 48 29 73 74 48 70 63 70 120 61 59 187 69 60 56 24 46 91 86 66 208 227 61 550 82 112 46 34 2 0 0 0 0 0 0 0 0 20 0 2 0 39 COG0106(Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase) 251 172 175 190 17 32 67 69 32 23 30 50 18 63 29 42 82 83 46 62 70 48 121 73 107 149 62 100 59 18 72 111 125 83 244 274 78 347 61 85 42 61 0 2 1 1 1 1 4 0 2 36 0 0 1 53 COG0245(2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase) 187 163 187 187 14 22 67 70 31 18 23 41 18 58 50 37 69 89 43 60 77 56 146 67 88 166 66 72 76 23 85 122 120 78 256 305 66 393 86 76 32 39 0 0 0 0 0 1 0 0 0 34 1 2 0 58 COG0080(Ribosomal protein L11) 138 151 170 196 16 14 62 66 34 31 14 41 28 118 36 54 80 71 35 75 81 65 134 67 76 184 51 81 66 23 73 118 114 97 259 287 95 380 92 70 43 36 2 3 0 0 0 0 1 0 0 31 1 1 2 56 COG0386(Glutathione peroxidase) 276 221 205 179 19 33 71 80 29 49 30 36 25 79 38 38 65 52 55 86 64 62 142 61 85 78 64 76 71 29 76 137 105 95 312 258 50 233 69 107 47 32 0 1 1 1 1 0 0 0 0 30 0 1 1 64 COG4191(Signal transduction histidine kinase regulating C4-dicarboxylate transport system) 1293 94 70 78 6 16 20 39 20 19 30 38 10 69 30 33 44 34 34 36 25 32 45 39 39 87 54 31 19 18 25 53 68 36 149 161 167 753 51 44 19 22 1 0 0 0 0 0 0 0 0 12 0 0 0 53 COG0122(3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase) 356 193 232 238 9 23 34 54 15 22 13 45 11 67 48 50 72 52 51 83 68 54 137 60 85 137 69 82 71 13 70 134 124 70 249 259 51 264 63 92 35 38 2 0 0 1 0 0 0 0 2 41 0 1 0 69 COG1357(Uncharacterized low-complexity proteins) 378 102 163 173 78 52 33 46 15 24 14 37 35 58 43 32 49 44 37 58 98 72 155 77 107 126 67 69 64 80 68 107 81 43 106 214 129 543 127 55 34 33 0 0 0 1 0 0 0 0 0 31 2 1 0 48 COG1167(Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs) 1793 112 88 100 17 13 30 25 23 18 10 14 21 70 27 18 43 72 70 35 15 19 66 33 35 130 34 25 46 12 44 91 52 41 154 83 28 295 46 66 15 29 0 0 0 0 0 0 0 0 0 17 0 0 3 30 COG2951(Membrane-bound lytic murein transglycosylase B) 351 194 244 163 12 16 44 61 40 33 36 51 24 85 28 54 32 36 51 76 69 69 142 58 74 36 65 68 68 10 75 121 104 75 271 302 71 331 76 109 28 52 0 1 0 0 0 0 0 0 0 37 0 0 0 55 COG1043(Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase) 254 199 223 226 25 31 66 69 24 25 22 34 15 30 42 63 31 47 44 77 91 72 147 96 84 64 71 72 75 26 70 141 106 111 268 293 61 249 73 83 43 50 0 0 0 0 0 1 0 1 2 31 0 4 0 60 COG2224(Isocitrate lyase) 324 226 218 182 16 8 69 66 37 53 22 46 40 40 41 47 39 38 55 92 68 67 130 78 58 67 77 72 68 9 64 139 98 62 268 345 79 207 58 88 57 33 0 2 4 0 0 0 0 1 0 30 0 0 0 92 COG2319(FOG: WD40 repeat) 194 147 401 205 122 231 29 29 6 37 20 4 21 107 94 18 15 27 107 48 108 71 125 102 83 48 40 46 42 244 54 77 50 30 36 103 70 568 45 48 29 15 0 0 0 0 1 0 0 0 0 25 0 0 0 50 COG1663(Tetraacyldisaccharide-1-P 4-kinase) 258 209 248 204 23 26 72 84 19 20 35 25 37 54 47 16 57 42 47 71 54 63 136 87 75 46 72 81 82 13 55 142 98 85 277 331 61 235 78 95 42 55 0 0 0 0 0 0 1 2 2 35 0 0 0 75 COG0259(Pyridoxamine-phosphate oxidase) 261 182 186 180 15 18 51 51 30 51 12 42 34 75 43 51 68 63 57 58 82 58 116 56 70 135 57 66 66 11 53 112 111 76 263 266 61 415 60 86 47 49 0 1 0 0 0 1 1 0 0 52 0 2 0 69 COG4145(Na+/panthothenate symporter) 203 209 150 211 2 8 57 86 18 32 43 61 32 79 46 67 72 57 53 109 82 67 149 75 81 37 65 82 89 4 72 130 125 75 250 352 53 201 75 71 48 39 0 2 0 0 1 2 0 3 0 48 0 2 1 82 COG0349(Ribonuclease D) 181 188 153 160 10 33 42 61 28 18 28 26 37 52 43 44 70 88 62 57 71 73 95 66 74 186 83 68 81 37 61 92 121 72 238 262 59 516 74 54 38 46 0 2 0 0 0 1 0 1 0 37 0 0 2 64 COG0200(Ribosomal protein L15) 165 190 170 178 22 18 74 72 27 26 26 35 34 73 42 41 59 73 53 56 79 62 143 70 85 186 62 61 64 26 72 136 115 95 212 271 60 398 70 81 30 37 0 0 1 1 0 0 1 0 0 38 0 0 0 62 COG0787(Alanine racemase) 246 114 172 131 34 21 55 57 31 29 22 24 11 71 25 45 90 73 67 50 54 67 125 80 63 213 78 70 88 22 61 132 80 74 225 202 65 564 63 91 45 9 0 2 2 0 1 0 0 1 0 46 0 0 1 58 COG0334(Glutamate dehydrogenase/leucine dehydrogenase) 200 134 242 120 31 17 54 31 39 34 31 33 29 67 53 36 53 72 52 86 60 87 125 57 50 154 82 64 82 29 51 157 99 100 241 236 93 338 80 121 45 56 0 0 1 0 0 2 1 1 0 38 0 0 4 75 COG4232(Thiol:disulfide interchange protein) 465 198 226 142 23 14 56 55 38 25 40 33 28 77 46 37 46 47 51 56 35 61 78 53 58 76 74 44 50 16 39 129 89 99 281 250 82 412 57 77 46 40 0 0 0 2 0 0 0 4 0 29 2 0 0 45 COG0406(Fructose-2,6-bisphosphatase) 337 72 116 77 10 28 24 39 25 5 16 6 19 65 23 36 146 173 62 43 55 58 95 43 69 472 63 69 36 38 29 107 58 55 124 125 61 782 82 55 27 37 0 0 0 0 0 1 0 0 0 22 0 0 0 45 COG0414(Panthothenate synthetase) 225 131 145 162 22 20 68 67 21 25 36 47 18 60 39 41 70 56 48 70 99 78 119 81 60 134 76 87 71 29 71 122 80 78 264 267 57 405 95 102 39 40 0 1 0 0 0 0 0 0 2 36 0 0 1 58 COG0355(F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)) 199 220 216 203 9 23 50 62 22 39 17 35 25 52 34 49 70 64 34 58 84 71 139 77 108 110 69 74 75 20 65 118 109 80 260 303 61 244 89 80 44 44 0 1 1 0 0 0 0 0 0 46 0 0 0 62 COG0628(Predicted permease) 503 101 208 136 24 23 40 30 17 25 46 18 14 50 24 30 57 51 53 60 75 60 105 62 70 154 49 47 39 42 37 110 59 61 143 181 115 671 93 67 32 37 0 0 0 0 0 2 0 0 0 21 1 0 0 64 COG0530(Ca2+/Na+ antiporter) 498 165 180 141 23 25 39 36 16 30 25 9 14 57 36 31 33 42 49 47 82 71 121 68 88 28 48 80 76 47 68 118 85 68 195 235 109 508 73 81 37 25 3 0 1 0 0 0 0 0 0 26 1 0 0 67 COG0197(Ribosomal protein L16/L10E) 154 198 186 196 14 17 63 55 31 26 27 40 29 74 26 49 60 56 46 76 65 61 141 94 87 171 64 69 67 20 69 108 124 68 214 245 89 383 70 88 36 31 0 0 1 0 2 0 0 0 0 46 0 0 0 61 COG0694(Thioredoxin-like proteins and domains) 164 166 161 162 26 19 75 81 34 27 30 48 24 41 42 56 47 54 45 71 78 64 152 79 94 88 59 81 80 34 58 128 115 96 265 323 74 242 82 130 44 33 3 1 2 0 0 0 0 1 0 56 0 0 0 62 COG3200(3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase) 147 208 171 212 8 22 49 64 34 38 12 34 19 30 45 48 82 112 36 97 67 58 117 64 85 170 68 67 64 7 45 136 107 94 254 309 52 316 71 72 40 45 0 0 0 0 0 2 0 1 0 45 0 1 0 71 COG0523(Putative GTPases (G3E family)) 652 187 218 229 48 59 47 22 15 5 28 7 13 47 7 11 12 7 16 57 122 112 220 125 135 40 37 66 77 79 77 81 55 35 100 51 50 385 106 52 16 28 0 0 0 0 0 0 0 0 0 38 2 0 0 120 COG0160(4-aminobutyrate aminotransferase and related aminotransferases) 435 82 306 113 9 9 25 26 19 7 13 22 21 43 26 32 104 129 37 59 42 70 108 35 50 270 53 65 43 14 35 118 111 80 150 282 53 428 65 134 28 36 0 0 2 0 0 0 0 0 0 32 0 0 0 68 COG4166(ABC-type oligopeptide transport system, periplasmic component) 405 188 221 183 8 31 46 42 30 22 20 26 28 99 41 42 30 21 66 48 53 83 111 59 43 67 65 60 57 16 59 104 94 75 213 232 76 523 72 73 26 45 0 0 0 2 0 0 2 0 0 39 0 0 0 39 COG0233(Ribosome recycling factor) 188 130 190 180 21 21 46 51 31 34 21 24 16 48 25 37 61 70 52 89 57 82 122 67 94 134 79 81 64 15 57 136 105 93 247 262 96 374 69 99 38 54 2 0 0 0 0 0 2 0 0 43 0 0 0 77 COG0256(Ribosomal protein L18) 178 201 172 167 22 19 59 53 18 17 22 28 13 69 51 45 93 73 40 52 67 65 135 67 74 146 69 78 69 16 74 97 126 69 240 278 77 351 97 93 30 57 0 0 1 0 0 0 1 0 0 45 0 0 0 62 COG4108(Peptide chain release factor RF-3) 310 66 70 98 42 24 63 40 36 39 37 28 20 97 22 33 73 48 48 43 56 56 113 73 74 153 74 58 45 30 64 114 79 42 140 194 92 872 92 89 34 11 0 0 0 0 0 0 0 0 0 26 0 0 0 56 COG3696(Putative silver efflux pump) 1875 128 44 35 13 10 17 11 7 22 44 13 9 141 30 37 121 101 79 8 24 19 31 14 18 104 32 15 16 7 13 23 22 26 54 60 90 479 22 8 10 6 0 1 0 0 0 0 0 0 0 15 0 0 0 17 COG1932(Phosphoserine aminotransferase) 198 151 225 146 26 19 70 44 28 18 38 24 23 84 40 33 67 87 73 80 61 74 102 49 93 183 77 69 58 11 36 90 108 61 207 290 47 453 75 96 28 40 0 1 0 1 0 0 0 2 0 31 0 0 0 52 COG2185(Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)) 63 109 223 98 16 12 25 87 51 29 55 27 45 117 53 32 23 38 34 71 69 95 102 49 39 272 87 58 46 19 33 126 127 71 111 142 21 842 36 79 56 51 0 0 0 0 0 0 0 0 0 49 0 1 0 80 COG0096(Ribosomal protein S8) 177 180 189 156 25 18 64 46 21 31 27 23 13 62 43 40 97 79 48 62 82 65 125 80 71 143 76 69 62 21 61 113 111 90 250 255 80 336 85 90 30 61 0 0 0 0 1 0 0 0 0 50 1 0 0 56 COG0611(Thiamine monophosphate kinase) 280 180 160 168 25 19 59 64 34 21 38 53 15 34 36 45 66 63 45 81 62 59 115 60 93 122 61 68 64 29 72 125 102 56 319 243 52 359 87 81 26 35 0 0 0 1 3 0 1 0 0 29 0 1 0 51 COG1262(Uncharacterized conserved protein) 383 83 156 106 56 63 57 64 32 38 59 30 70 90 45 40 64 55 93 46 59 79 118 57 53 99 61 62 55 43 44 91 74 49 201 181 44 531 58 100 28 42 0 0 2 0 0 0 0 0 0 36 0 0 1 53 COG0394(Protein-tyrosine-phosphatase) 509 218 206 199 28 30 86 36 17 17 19 20 12 62 29 26 66 75 47 86 76 90 141 61 63 217 54 45 52 16 40 75 73 56 163 136 52 435 51 52 17 19 0 2 0 0 1 0 0 0 0 24 0 0 0 46 COG0756(dUTPase) 169 135 160 139 29 4 49 59 57 31 24 45 54 61 41 65 93 103 59 87 54 42 90 58 59 256 69 77 54 4 43 92 128 79 239 270 81 353 63 106 40 23 0 0 2 0 0 2 0 2 0 25 0 0 0 68 COG0635(Coproporphyrinogen III oxidase and related Fe-S oxidoreductases) 465 71 82 80 34 22 22 44 28 24 49 34 23 87 35 36 93 107 46 44 72 68 91 51 56 216 66 45 44 36 50 105 78 45 184 165 78 713 78 75 36 21 0 0 0 0 0 0 0 0 0 18 0 0 0 24 COG0340(Biotin-(acetyl-CoA carboxylase) ligase) 224 155 196 169 15 25 54 61 29 18 10 31 41 63 41 34 55 68 53 68 101 75 135 71 62 112 56 74 64 19 60 144 95 81 242 243 55 367 85 96 48 27 1 0 2 0 0 1 0 0 0 42 0 2 0 66 COG0100(Ribosomal protein S11) 216 203 202 156 22 19 74 65 26 30 27 30 35 45 44 43 66 66 59 79 82 72 143 81 74 139 54 63 61 27 43 122 95 69 221 224 65 313 70 79 51 47 0 0 0 0 0 0 1 1 0 47 0 0 0 73 COG1386(Predicted transcriptional regulator containing the HTH domain) 238 190 191 173 11 9 57 64 16 30 25 26 17 58 20 37 80 72 39 88 76 73 150 67 88 152 48 61 60 19 49 117 109 62 209 252 60 399 67 70 48 46 0 1 0 0 0 0 0 0 0 30 0 0 0 63 COG0423(Glycyl-tRNA synthetase (class II)) 101 199 289 174 21 21 73 44 28 28 7 28 18 40 46 49 55 52 33 61 59 82 143 57 86 182 85 55 62 26 39 130 110 69 260 238 95 295 64 87 53 41 0 0 0 0 3 0 2 2 0 42 0 4 2 62 COG0679(Predicted permeases) 292 154 105 178 8 21 51 60 29 22 21 33 13 54 37 38 52 31 38 63 53 56 98 71 81 31 62 65 61 22 69 117 94 75 237 214 102 634 79 89 28 31 0 0 1 0 0 0 2 0 0 47 2 3 0 70 COG2897(Rhodanese-related sulfurtransferase) 231 154 157 213 12 12 45 48 24 29 27 30 8 51 50 42 117 75 50 64 56 78 118 51 68 105 72 63 55 9 50 117 99 68 195 235 48 578 59 74 27 35 2 0 0 0 0 0 0 1 2 26 0 1 0 62 COG0790(FOG: TPR repeat, SEL1 subfamily) 1038 110 304 166 27 89 32 28 25 16 21 13 27 118 58 34 55 38 65 34 36 59 85 40 44 93 56 72 29 18 46 51 35 29 90 195 50 284 29 54 25 10 0 0 0 1 0 0 0 0 0 25 2 2 0 33 COG1032(Fe-S oxidoreductase) 364 156 189 183 25 15 18 60 22 9 41 21 26 57 62 25 54 63 47 35 81 43 119 71 51 229 49 32 33 30 44 110 54 32 51 322 222 485 157 35 19 2 0 0 0 0 0 0 0 0 0 9 0 1 0 38 COG3173(Predicted aminoglycoside phosphotransferase) 151 189 290 163 21 15 78 34 39 37 13 24 10 81 44 29 44 50 76 109 58 91 142 72 65 147 75 67 74 21 53 142 104 70 231 275 31 226 74 81 40 51 1 0 0 0 0 0 2 0 0 37 0 0 0 60 COG0590(Cytosine/adenosine deaminases) 232 158 181 167 23 22 45 41 22 20 18 16 21 50 20 40 54 51 51 69 53 75 130 67 80 155 60 65 61 20 56 122 87 67 323 313 71 326 102 84 44 30 0 0 1 2 0 0 0 0 0 34 0 0 0 56 COG0102(Ribosomal protein L13) 184 167 172 167 25 17 84 59 17 26 26 31 32 56 51 35 64 70 30 54 93 65 153 71 76 132 62 78 66 28 53 112 107 81 274 238 60 314 71 93 40 49 2 2 2 0 0 0 1 0 0 27 1 0 0 65 COG1792(Cell shape-determining protein) 247 177 145 147 15 17 47 56 32 20 25 31 15 49 34 36 77 98 38 52 65 64 127 78 94 188 51 74 76 14 70 125 89 68 266 277 51 288 80 95 44 40 0 0 0 0 0 0 1 0 2 29 0 0 0 58 COG0689(RNase PH) 206 156 191 112 9 21 49 41 21 40 13 30 30 80 37 40 79 95 45 73 56 82 139 60 72 196 69 42 71 27 39 117 79 72 199 227 75 412 83 88 35 55 2 0 1 0 0 0 0 0 0 39 0 0 0 63 COG0130(Pseudouridine synthase) 180 157 204 152 13 33 59 59 32 35 21 28 8 64 43 37 82 68 59 60 73 67 112 59 73 193 55 48 63 38 54 122 87 76 196 169 113 426 107 78 42 26 0 0 0 0 0 0 0 2 0 38 0 0 0 55 COG0677(UDP-N-acetyl-D-mannosaminuronate dehydrogenase) 102 134 221 180 19 19 36 48 18 23 17 34 11 42 57 50 84 77 54 76 64 75 139 77 101 170 73 59 75 18 65 124 81 86 287 257 129 230 71 97 46 34 0 3 0 0 0 0 0 0 0 36 2 0 0 65 COG0854(Pyridoxal phosphate biosynthesis protein) 246 193 164 179 21 12 61 67 29 26 31 40 12 36 24 25 55 48 53 48 75 59 103 91 71 66 75 88 57 25 38 145 113 101 309 281 75 269 106 95 38 36 0 0 0 0 0 0 1 0 1 26 0 0 1 47 COG0782(Transcription elongation factor) 310 164 187 171 12 13 53 56 29 31 32 40 15 72 37 36 73 82 54 75 61 49 92 59 75 145 47 56 37 11 46 103 114 75 246 290 85 345 52 68 37 40 0 0 0 0 0 0 0 0 0 28 0 0 0 50 COG0093(Ribosomal protein L14) 149 208 163 186 24 22 57 56 19 28 14 27 26 55 39 53 74 58 41 74 70 67 114 79 82 155 45 62 59 19 76 92 110 87 239 248 75 335 79 85 35 52 0 0 0 1 1 0 0 0 0 42 1 0 0 68 COG0234(Co-chaperonin GroES (HSP10)) 225 149 163 169 24 18 82 73 30 36 33 25 31 91 45 34 65 74 55 65 62 63 146 74 62 155 71 79 68 20 52 101 105 76 233 259 65 260 60 68 37 38 0 0 0 0 0 0 0 0 2 39 0 0 0 63 COG0125(Thymidylate kinase) 224 151 196 173 7 22 35 39 14 12 15 37 21 48 38 32 68 90 39 86 86 96 154 59 94 208 44 63 41 11 58 103 92 90 218 257 68 347 73 70 40 35 0 0 0 3 0 1 0 0 2 33 0 0 0 52 COG3917(2-hydroxychromene-2-carboxylate isomerase) 224 257 275 212 22 16 63 59 37 36 26 25 24 71 49 45 47 52 54 67 59 77 121 82 72 52 68 74 59 9 53 126 133 78 286 265 42 116 49 92 42 33 0 0 0 1 0 0 0 0 0 34 0 0 0 59 COG0381(UDP-N-acetylglucosamine 2-epimerase) 171 147 206 162 19 20 63 34 30 18 18 28 12 38 42 37 68 60 51 66 76 55 128 84 70 125 85 91 72 16 66 125 92 99 228 345 81 271 73 80 55 24 4 1 0 0 0 0 0 0 0 37 0 0 0 64 COG1070(Sugar (pentulose and hexulose) kinases) 508 102 119 117 20 19 41 37 10 27 13 17 20 65 24 13 75 80 39 35 79 54 102 60 59 231 35 36 46 28 51 125 81 77 248 158 56 508 78 87 31 41 0 0 0 0 0 0 2 1 2 42 1 0 0 35 COG2366(Protein related to penicillin acylase) 160 118 274 128 16 11 35 61 45 37 40 40 21 74 57 47 51 34 50 74 52 70 103 37 71 80 103 68 56 15 32 123 117 88 199 235 26 531 56 103 48 41 0 4 0 0 0 0 0 0 0 30 2 1 0 70 COG0573(ABC-type phosphate transport system, permease component) 316 274 225 272 5 28 89 25 3 9 38 10 8 46 30 84 95 99 59 141 121 123 203 128 126 215 62 27 34 18 27 29 13 14 47 40 24 468 31 10 7 12 0 0 0 0 0 0 0 2 0 8 1 0 0 85 COG0377(NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases) 190 174 180 188 11 11 58 46 23 27 10 29 28 107 41 45 88 78 38 65 83 84 132 81 76 214 65 85 63 21 62 117 86 102 160 288 25 192 81 59 38 42 0 0 1 0 0 0 2 0 0 42 1 0 1 89 COG0379(Quinolinate synthase) 240 198 129 183 15 15 54 77 23 23 14 36 36 81 39 48 69 76 46 79 81 86 120 85 88 144 63 59 60 26 61 115 76 48 215 248 51 305 76 65 32 42 2 0 2 2 0 0 0 0 0 29 0 1 0 59 COG0091(Ribosomal protein L22) 141 159 165 179 18 13 58 51 22 26 17 39 38 79 31 32 79 64 38 81 87 66 138 88 81 129 63 80 68 21 58 112 105 69 227 238 67 363 74 75 47 45 0 0 0 1 0 0 0 0 0 38 0 0 0 51 COG0135(Phosphoribosylanthranilate isomerase) 240 153 169 183 22 21 67 68 23 38 23 38 30 79 51 29 57 47 76 66 77 59 143 73 87 64 59 67 63 14 84 139 98 77 263 261 54 244 64 74 37 31 0 0 2 0 0 3 0 1 0 42 0 1 0 53 COG1744(Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein) 140 135 141 128 5 16 45 35 18 20 18 15 19 104 21 29 68 83 38 89 71 72 131 75 58 228 70 76 76 13 43 133 110 90 267 286 40 300 96 82 54 40 0 0 0 1 1 0 0 0 0 34 0 0 0 93 COG0040(ATP phosphoribosyltransferase) 266 169 142 186 20 24 50 78 23 18 13 36 16 60 44 36 84 73 49 54 65 61 108 72 82 100 47 69 64 22 61 127 87 76 218 247 58 389 50 63 36 45 0 0 1 0 0 0 0 0 1 37 2 0 0 76 COG1057(Nicotinic acid mononucleotide adenylyltransferase) 195 172 166 175 22 11 50 52 27 15 30 41 14 41 59 31 49 54 49 57 76 70 99 74 73 155 68 68 78 18 66 116 98 80 231 268 46 391 58 90 40 45 0 0 3 0 0 1 1 0 0 33 0 0 0 46 COG0440(Acetolactate synthase, small (regulatory) subunit) 210 195 165 177 15 21 54 51 26 23 8 26 42 71 52 53 74 66 47 87 65 82 122 85 61 138 63 72 61 13 73 130 92 79 205 269 49 273 60 69 45 20 0 1 0 0 2 0 0 1 0 35 0 0 0 74 COG0103(Ribosomal protein S9) 163 148 180 173 24 19 69 64 16 19 24 31 25 68 54 33 67 77 29 67 81 61 142 82 74 107 63 67 54 27 51 110 104 73 279 247 61 332 76 72 35 49 1 2 2 0 1 0 1 0 0 30 1 0 1 63 COG1014(Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit) 438 162 280 163 10 24 65 32 38 10 14 17 17 105 39 34 37 19 74 89 59 83 136 86 72 88 62 87 58 14 32 89 69 39 153 182 91 339 33 51 48 51 0 0 0 0 0 0 0 0 0 27 0 0 2 79 COG4603(ABC-type uncharacterized transport system, permease component) 145 139 135 149 3 17 46 12 23 26 23 22 23 102 24 31 39 67 52 94 57 71 128 72 72 162 66 75 64 4 47 117 100 116 271 296 45 348 91 102 55 47 0 1 0 0 3 1 0 0 0 42 0 0 0 70 COG0742(N6-adenine-specific methylase) 208 174 218 170 18 16 47 60 26 24 18 35 20 36 46 34 60 67 44 47 71 59 139 94 79 119 80 81 61 20 56 114 120 57 251 241 50 328 66 86 40 31 1 0 0 1 0 0 0 0 2 32 0 0 0 47 COG0005(Purine nucleoside phosphorylase) 160 168 204 194 8 15 42 22 7 17 14 26 37 60 31 33 59 58 48 91 89 85 141 94 88 141 61 75 61 25 54 101 87 75 182 276 59 372 77 76 35 39 0 0 1 0 0 0 0 0 0 32 0 0 0 74 COG0222(Ribosomal protein L7/L12) 172 133 158 183 15 14 75 50 30 24 19 36 18 136 27 45 64 67 33 68 97 73 96 64 92 124 72 50 71 23 65 118 88 103 244 262 56 328 59 74 30 38 0 0 0 0 0 0 0 0 0 33 0 0 0 61 COG0691(tmRNA-binding protein) 186 162 178 159 34 18 54 64 22 27 13 36 23 59 37 30 66 82 61 83 63 61 119 84 84 148 60 61 69 29 63 105 88 75 219 256 54 358 74 84 30 28 0 0 0 0 0 0 0 0 0 31 0 0 0 50 COG1045(Serine acetyltransferase) 380 157 153 154 14 23 56 57 22 31 44 20 13 61 31 43 40 54 48 56 73 75 109 82 116 62 63 49 63 21 67 111 103 42 226 223 48 374 83 73 31 34 0 0 2 0 0 0 0 1 0 41 1 0 1 55 COG0497(ATPase involved in DNA repair) 236 59 119 79 25 27 36 25 28 15 26 30 20 76 35 31 89 130 46 34 84 45 107 36 54 230 54 78 61 37 59 91 58 63 179 154 52 770 80 111 29 27 0 0 0 1 2 0 0 0 0 22 0 0 0 36 COG0354(Predicted aminomethyltransferase related to GcvT) 247 179 150 171 7 28 51 59 30 24 12 39 32 57 33 23 80 81 43 68 47 64 101 77 77 155 44 59 57 9 93 114 83 72 225 271 51 386 68 70 26 33 0 0 0 0 2 0 0 0 0 36 0 2 0 38 COG0270(Site-specific DNA methylase) 518 87 144 116 26 29 31 79 17 30 63 30 24 60 49 39 73 104 84 81 42 61 87 55 35 189 46 64 54 50 37 85 87 63 104 192 89 372 33 80 26 46 0 0 0 2 0 0 1 0 0 43 0 0 0 46 COG0105(Nucleoside diphosphate kinase) 189 133 201 175 24 17 41 63 27 32 22 22 32 73 39 35 85 77 53 61 66 85 103 56 90 151 61 60 65 26 65 103 87 68 196 283 94 309 63 78 26 39 0 0 1 0 0 1 0 0 0 35 2 0 1 58 COG1098(Predicted RNA binding protein (contains ribosomal protein S1 domain)) 423 123 152 137 14 16 54 49 26 34 27 19 30 57 39 22 72 50 54 40 54 63 110 60 87 158 51 67 46 12 43 92 92 58 174 184 67 586 48 74 17 29 0 0 2 0 0 1 0 0 0 23 0 0 0 30 COG0416(Fatty acid/phospholipid biosynthesis enzyme) 218 158 168 175 14 15 63 57 22 34 18 34 9 42 43 40 45 62 48 58 92 63 116 81 67 107 89 83 53 20 87 138 117 83 250 286 71 176 102 74 44 39 0 0 0 0 0 0 0 2 0 34 0 0 1 66 COG2972(Predicted signal transduction protein with a C-terminal ATPase domain) 1006 116 97 110 20 15 41 45 13 6 14 31 9 45 35 40 51 49 34 33 80 37 128 56 75 74 55 52 53 33 45 49 50 48 159 143 119 412 42 45 29 15 0 0 1 0 0 0 0 0 0 17 0 0 2 35 COG0203(Ribosomal protein L17) 174 154 154 186 15 15 58 48 21 30 28 37 20 47 49 32 64 72 35 60 61 79 125 58 68 137 70 63 60 16 63 109 115 68 254 233 58 396 78 82 36 35 0 1 0 0 0 0 1 1 0 45 0 1 0 51 COG0099(Ribosomal protein S13) 181 208 201 147 18 15 67 47 31 25 26 29 20 60 45 40 67 66 62 67 83 81 137 80 65 133 63 64 53 22 38 127 98 69 195 243 55 301 63 76 41 46 0 0 0 0 0 0 2 0 0 41 0 0 0 65 COG0666(FOG: Ankyrin repeat) 262 173 231 239 214 310 33 68 16 24 18 12 24 67 39 25 76 99 59 34 39 73 140 38 66 110 55 43 20 216 36 54 29 1 29 185 184 218 14 20 12 10 0 0 0 2 0 0 0 0 0 16 0 1 2 26 COG0326(Molecular chaperone, HSP90 family) 223 130 164 124 61 31 44 76 31 40 36 26 27 88 48 33 45 41 50 47 74 60 132 80 88 38 74 62 64 46 64 157 93 100 291 184 71 270 74 103 28 32 0 0 0 0 1 0 0 0 0 40 0 1 2 46 COG0017(Aspartyl/asparaginyl-tRNA synthetases) 234 84 191 79 31 13 28 42 24 23 10 37 32 58 24 34 57 73 44 50 68 92 106 52 87 137 47 40 45 24 25 119 83 70 169 217 96 693 48 110 40 26 2 0 0 0 0 0 0 0 0 20 0 0 0 52 COG0588(Phosphoglycerate mutase 1) 171 237 225 213 7 16 39 55 24 33 26 35 20 55 27 27 58 76 39 69 74 58 124 63 71 158 60 66 74 37 52 114 124 74 218 283 52 156 56 71 42 42 0 0 1 0 0 2 0 1 0 38 0 0 0 69 COG0849(Actin-like ATPase involved in cell division) 176 183 241 186 22 16 56 50 43 19 18 41 33 57 37 20 60 64 44 59 52 49 110 58 68 87 65 57 66 14 63 112 100 72 254 253 94 300 68 92 35 39 0 1 3 0 0 0 0 0 0 31 0 0 0 61 COG0802(Predicted ATPase or kinase) 189 166 184 169 17 15 66 53 29 20 13 33 18 66 28 39 64 43 48 74 75 71 147 60 67 140 65 64 59 21 52 110 106 63 275 262 57 275 67 78 49 38 0 2 0 1 2 0 2 0 0 27 0 0 0 55 COG0669(Phosphopantetheine adenylyltransferase) 205 188 169 156 20 17 58 51 33 32 25 27 11 63 37 43 62 68 46 53 54 61 133 71 69 127 70 68 64 17 49 116 115 87 257 220 53 297 82 87 36 42 0 0 1 0 0 0 0 1 0 43 0 0 0 37 COG1143(Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)) 196 151 154 172 10 9 45 40 16 22 18 44 13 49 41 37 96 90 43 66 69 63 155 77 66 224 64 76 72 18 66 108 108 85 182 284 43 198 58 71 40 54 0 0 0 1 2 0 3 2 0 55 0 0 0 58 COG3705(ATP phosphoribosyltransferase involved in histidine biosynthesis) 206 203 157 182 11 17 61 72 16 13 19 42 16 41 51 25 44 31 30 65 78 49 126 76 83 47 55 61 59 14 83 140 113 71 226 251 49 346 78 99 35 31 2 0 0 0 0 2 0 0 0 51 3 0 2 70 COG0359(Ribosomal protein L9) 172 143 189 161 6 17 44 46 29 22 26 23 24 38 46 49 64 72 50 51 75 71 119 71 86 129 74 67 67 21 69 122 97 71 246 245 58 313 66 79 43 43 0 0 1 0 1 0 0 0 0 37 3 0 2 52 COG0757(3-dehydroquinate dehydratase II) 239 181 187 164 13 13 42 61 26 34 19 33 26 41 48 46 56 60 46 50 58 64 114 71 96 108 54 65 53 18 58 123 98 88 283 267 57 255 64 61 30 38 1 0 0 1 0 0 0 1 1 33 1 0 0 49 COG1605(Chorismate mutase) 357 167 162 112 14 17 31 28 29 63 27 29 25 69 32 45 43 40 54 59 35 45 91 47 54 123 57 54 24 13 28 71 99 68 136 221 47 664 74 77 25 25 0 0 0 0 0 0 0 0 0 20 0 0 0 81 COG3748(Predicted membrane protein) 190 190 237 246 9 19 55 47 15 20 19 18 10 64 44 40 47 27 43 71 59 71 130 103 75 67 68 82 61 10 49 134 125 82 292 340 67 34 84 88 30 28 0 0 0 0 0 0 0 3 0 22 0 0 0 63 COG2252(Permeases) 418 226 171 207 11 17 50 77 23 34 12 42 27 55 39 61 93 77 28 64 49 57 110 73 59 113 34 43 46 25 54 108 135 78 218 230 55 62 43 78 30 33 1 1 0 2 0 0 1 0 0 47 0 0 1 56 COG1235(Metal-dependent hydrolases of the beta-lactamase superfamily I) 228 128 98 141 19 25 60 58 29 19 23 34 22 71 40 36 57 64 54 66 50 58 113 58 71 108 77 69 57 7 64 100 103 113 273 237 58 331 60 97 34 50 0 0 0 0 0 0 2 0 0 40 0 0 0 67 COG1115(Na+/alanine symporter) 371 175 272 141 27 19 61 50 37 34 24 50 46 91 41 39 21 26 60 75 60 87 112 68 47 7 56 64 43 19 40 117 105 34 257 209 39 198 85 99 37 50 0 0 2 0 0 2 0 0 0 29 0 1 2 39 COG3976(Uncharacterized protein conserved in bacteria) 318 218 158 154 3 18 57 37 10 28 18 18 30 32 20 35 62 60 32 47 80 59 98 68 68 86 73 75 78 10 63 112 112 64 197 200 51 338 87 90 42 47 2 2 0 1 0 0 0 0 0 30 0 0 0 78 COG2076(Membrane transporters of cations and cationic drugs) 277 187 175 172 6 14 43 51 22 19 35 52 25 28 44 31 46 35 30 71 53 61 114 72 76 22 69 66 59 11 64 122 131 67 328 321 61 138 74 87 36 41 2 1 0 0 0 0 2 5 0 38 1 1 0 77 COG0839(NADH:ubiquinone oxidoreductase subunit 6 (chain J)) 215 150 160 172 6 13 45 46 12 31 21 42 13 59 40 52 86 79 38 59 78 70 159 91 67 192 70 76 71 13 58 100 123 93 169 256 50 153 61 71 44 29 0 0 0 0 2 0 3 0 0 36 0 0 0 87 COG0292(Ribosomal protein L20) 172 182 190 190 21 14 64 65 18 32 18 24 14 43 26 39 67 61 41 63 73 60 129 67 85 121 67 71 68 18 53 117 109 63 229 246 58 285 73 79 26 33 0 1 0 0 0 0 0 2 0 26 0 0 0 52 COG1570(Exonuclease VII, large subunit) 214 131 211 135 17 17 45 39 20 25 35 20 22 80 18 21 62 76 61 56 53 49 100 52 57 208 69 52 36 15 20 124 83 41 191 180 65 587 69 66 24 32 1 0 0 0 0 0 0 0 0 38 0 0 0 34 COG0144(tRNA and rRNA cytosine-C5-methylases) 427 62 141 97 22 36 36 37 20 35 27 27 24 90 19 36 78 78 73 45 47 53 113 48 74 139 58 58 57 38 42 86 64 64 145 135 81 571 60 80 28 27 0 0 0 0 0 1 0 0 0 20 0 0 2 43 COG0205(6-phosphofructokinase) 85 163 245 126 26 16 66 28 21 17 24 18 20 66 45 41 60 70 41 73 55 70 132 75 87 141 71 70 51 17 42 118 121 49 203 242 70 372 67 75 29 35 0 0 0 0 0 0 0 0 0 41 0 0 0 60 COG0048(Ribosomal protein S12) 165 179 177 194 27 25 61 46 28 12 11 28 21 53 41 37 74 71 53 60 79 76 107 80 63 136 46 79 49 19 54 97 93 76 196 239 94 289 64 70 36 38 0 0 0 0 0 0 0 0 0 45 0 0 0 49 COG2755(Lysophospholipase L1 and related esterases) 287 103 202 127 26 20 43 54 29 21 23 32 20 57 41 32 101 89 57 53 51 80 101 52 89 174 64 71 45 21 40 100 80 72 210 162 56 385 68 70 27 35 0 1 0 0 0 0 0 1 0 20 0 0 0 41 COG1079(Uncharacterized ABC-type transport system, permease component) 151 128 136 122 4 21 56 28 18 14 26 20 12 90 22 25 49 63 57 91 55 58 115 79 58 155 78 77 73 1 50 123 92 116 210 266 56 363 72 84 56 44 2 0 0 0 3 2 0 0 0 39 0 0 0 72 COG1565(Uncharacterized conserved protein) 235 168 159 184 9 22 61 78 19 22 23 36 12 46 39 25 61 57 45 56 85 61 115 90 85 90 71 69 76 16 74 76 106 85 245 304 40 145 81 92 43 31 0 0 0 0 0 0 1 0 0 29 0 0 0 60 COG1091(dTDP-4-dehydrorhamnose reductase) 353 80 116 113 27 12 32 44 28 16 33 31 25 77 50 25 82 77 43 28 43 62 80 58 61 129 44 68 41 22 34 88 101 70 144 238 109 557 58 71 41 32 2 1 0 2 0 0 0 0 0 17 0 0 0 59 COG0507(ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member) 698 70 73 93 42 34 37 50 30 24 31 29 16 70 27 40 71 66 50 39 40 31 76 44 55 66 44 47 34 42 44 63 59 39 104 117 108 700 92 43 18 17 0 0 2 0 0 0 0 0 0 20 0 0 1 25 COG5022(Myosin heavy chain) 254 102 274 148 107 192 33 90 19 39 35 41 46 59 29 24 46 63 56 54 56 66 109 40 92 84 62 58 41 206 34 89 77 52 72 157 160 126 45 34 49 19 0 0 0 0 0 0 1 0 0 23 0 0 0 58 COG2148(Sugar transferases involved in lipopolysaccharide synthesis) 535 74 161 101 20 8 24 46 24 27 20 27 16 51 45 32 65 51 45 33 62 51 93 56 68 77 56 58 36 32 37 78 63 55 200 165 95 537 63 86 36 21 0 0 0 0 0 0 0 0 0 20 0 1 0 65 COG0578(Glycerol-3-phosphate dehydrogenase) 286 130 105 98 15 22 52 32 21 18 43 30 19 108 46 45 64 77 47 69 34 58 65 57 56 148 72 68 43 13 30 115 64 78 210 159 81 553 84 76 24 27 0 0 0 0 0 0 0 0 0 22 0 0 0 52 COG0581(ABC-type phosphate transport system, permease component) 305 239 205 254 7 23 75 22 5 13 26 8 6 36 18 59 69 110 40 121 137 127 195 127 118 193 54 37 31 22 23 23 28 14 51 26 23 524 15 10 7 8 0 0 0 0 0 0 0 0 0 7 0 0 0 72 COG1195(Recombinational DNA repair ATPase (RecF pathway)) 160 165 189 143 19 19 51 35 33 27 32 22 5 65 34 28 40 75 47 50 56 72 91 75 79 187 62 49 65 21 56 119 93 46 249 242 59 372 80 87 25 35 0 0 0 1 0 0 0 0 1 18 2 0 0 28 COG2080(Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs) 512 119 178 127 15 21 19 47 17 19 19 15 13 94 25 37 53 52 52 79 67 73 95 65 79 178 72 60 38 12 35 95 73 54 121 265 69 272 72 82 15 25 1 0 0 0 0 0 0 0 0 13 0 0 0 63 COG0565(rRNA methylase) 227 195 172 190 11 20 54 59 16 31 32 31 20 76 35 50 47 32 41 60 76 55 124 89 79 41 63 66 60 17 60 115 82 66 216 287 67 200 92 62 53 35 1 2 0 0 0 0 0 0 0 37 0 1 0 60 COG3386(Gluconolactonase) 372 138 221 197 13 24 58 57 24 29 21 26 29 61 31 40 70 68 54 65 65 67 108 51 62 82 97 57 47 12 37 73 61 67 258 216 46 210 76 62 35 31 0 2 0 0 0 0 1 3 0 30 0 0 0 41 COG3300(MHYT domain (predicted integral membrane sensor domain)) 2850 60 29 4 0 4 0 5 0 1 16 3 2 17 2 5 21 38 6 7 4 3 4 4 10 74 13 2 12 8 2 10 8 3 15 6 64 153 8 11 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG0575(CDP-diglyceride synthetase) 224 122 149 161 17 18 50 56 22 9 19 29 13 52 39 38 83 72 38 71 87 59 130 67 65 126 70 61 49 21 40 103 99 73 196 205 64 400 68 68 33 29 0 0 0 0 0 1 0 0 0 25 0 0 0 69 COG2844(UTP:GlnB (protein PII) uridylyltransferase) 269 128 157 138 14 24 34 32 25 31 36 19 19 82 52 32 81 56 66 83 42 45 103 55 50 94 56 46 36 17 36 94 87 58 243 213 68 528 54 75 11 23 2 0 0 0 0 0 2 0 0 27 0 0 2 43 COG1201(Lhr-like helicases) 405 75 71 53 17 31 21 17 8 7 9 5 9 43 18 12 2 10 27 80 77 69 136 84 83 113 51 60 60 49 56 116 65 68 105 116 69 796 81 81 54 57 0 0 4 0 1 0 0 0 0 31 1 1 0 83 COG0185(Ribosomal protein S19) 137 155 171 151 14 13 46 52 19 28 17 34 30 93 33 24 64 61 36 76 80 80 125 82 76 109 72 84 54 22 60 100 90 69 204 219 54 346 68 74 45 30 0 0 0 1 0 0 1 0 0 44 0 0 0 44 COG5360(Uncharacterized protein conserved in bacteria) 152 175 132 221 5 21 56 61 21 28 23 44 11 54 32 39 42 34 38 57 85 69 114 65 84 57 65 85 68 2 46 127 132 81 337 314 48 82 73 95 46 52 0 0 0 2 0 0 0 0 4 40 0 0 0 60 COG0820(Predicted Fe-S-cluster redox enzyme) 211 125 187 148 27 22 44 49 40 36 32 40 21 74 34 32 74 109 54 50 61 54 115 53 67 201 49 52 63 19 57 95 96 59 213 151 62 363 50 83 23 17 0 0 0 0 0 0 0 0 0 38 0 2 0 26 COG1087(UDP-glucose 4-epimerase) 240 126 142 110 34 24 33 53 21 20 21 15 18 68 32 22 112 95 43 48 74 56 122 66 76 236 61 75 60 25 43 88 76 77 160 208 50 377 72 45 41 29 0 0 0 2 0 4 2 0 0 37 0 0 0 39 COG1183(Phosphatidylserine synthase) 168 169 175 167 9 19 42 88 34 42 32 47 22 87 48 55 78 57 80 51 55 61 97 53 58 69 57 51 61 10 49 89 104 91 299 275 64 118 68 76 38 49 1 0 2 0 0 2 0 1 0 40 0 1 2 55 COG2041(Sulfite oxidase and related enzymes) 305 105 160 135 11 20 16 46 42 32 18 34 32 68 23 59 118 98 62 84 49 29 76 50 62 137 68 35 31 15 38 101 96 66 163 210 80 446 53 51 28 28 0 0 0 0 0 0 0 0 0 24 0 0 0 48 COG0643(Chemotaxis protein histidine kinase and related kinases) 1427 113 67 50 12 10 23 10 3 2 29 13 8 51 10 14 48 45 13 7 19 34 45 28 22 72 52 27 34 18 15 31 17 14 35 37 323 598 16 13 6 12 0 0 0 0 2 0 0 0 0 12 0 0 0 13 COG0816(Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)) 201 161 159 161 9 15 46 79 30 28 21 35 13 43 34 48 80 73 34 53 78 61 102 81 57 82 70 67 53 18 51 124 85 68 218 231 42 327 77 74 30 39 0 1 0 0 1 1 1 2 6 32 0 0 0 47 COG4105(DNA uptake lipoprotein) 196 167 179 172 15 12 50 65 26 17 25 24 9 63 27 43 53 42 34 47 51 59 110 58 83 62 68 90 66 18 53 127 103 88 280 248 81 220 62 100 33 52 0 0 3 0 0 0 0 0 0 17 0 0 0 49 COG0560(Phosphoserine phosphatase) 341 104 145 88 7 10 34 37 25 21 24 22 25 67 38 31 111 122 77 57 44 52 77 38 58 207 38 49 41 17 28 69 76 51 134 173 55 652 41 43 26 27 0 0 0 0 0 0 0 0 1 21 0 0 0 42 COG3391(Uncharacterized conserved protein) 478 88 291 102 34 14 29 41 41 12 11 30 46 83 31 26 116 98 64 41 61 57 105 26 34 274 32 38 20 10 25 81 79 52 90 140 68 352 31 78 23 37 0 0 0 0 4 0 0 0 0 20 0 0 0 33 COG2270(Permeases of the major facilitator superfamily) 95 155 203 140 23 14 63 59 28 26 7 22 25 63 32 38 24 16 38 91 85 97 161 51 87 41 84 54 85 20 65 104 107 72 192 351 29 228 75 86 51 27 0 0 0 0 4 1 0 0 2 50 0 0 0 74 COG0157(Nicotinate-nucleotide pyrophosphorylase) 257 157 128 145 15 12 44 66 27 4 24 22 17 54 49 32 42 68 52 54 66 69 130 82 89 123 61 59 63 20 54 106 76 51 208 224 72 322 57 86 30 36 0 2 2 0 0 3 0 0 0 32 0 0 0 39 COG0051(Ribosomal protein S10) 145 189 169 147 22 19 64 38 24 30 11 27 30 86 37 30 60 62 49 74 71 69 121 81 76 116 48 76 67 11 49 116 82 75 188 194 72 287 73 76 33 37 2 0 0 0 0 0 0 0 0 30 1 2 0 64 COG0184(Ribosomal protein S15P/S13E) 188 177 181 155 12 14 70 63 28 36 17 33 36 43 31 37 63 55 39 68 74 62 101 69 80 115 54 46 61 19 43 107 106 76 250 208 47 259 58 78 32 36 0 1 0 1 0 1 1 0 0 34 1 0 0 61 COG0361(Translation initiation factor 1 (IF-1)) 186 149 160 157 15 12 56 49 25 45 24 36 21 77 32 46 58 78 51 70 75 60 124 64 63 121 61 68 56 18 41 101 97 68 154 261 61 262 81 76 40 22 2 0 0 0 1 0 0 2 0 36 0 0 2 56 COG2001(Uncharacterized protein conserved in bacteria) 210 140 155 131 15 11 68 56 29 30 23 38 18 116 44 40 69 62 40 63 58 50 107 54 62 107 84 45 55 9 49 91 87 71 248 195 71 297 44 73 39 41 1 0 2 0 0 1 0 2 0 38 0 1 0 71 COG4805(Uncharacterized protein conserved in bacteria) 455 198 238 130 25 7 52 40 29 28 38 36 29 75 30 48 44 43 69 57 51 58 121 52 41 164 55 67 47 25 37 104 87 49 179 193 30 128 47 51 37 31 2 0 4 1 0 0 0 0 0 27 0 2 0 50 COG0212(5-formyltetrahydrofolate cyclo-ligase) 176 183 153 172 18 16 56 46 19 28 17 30 24 52 30 36 60 52 41 42 75 68 111 76 74 106 64 54 56 19 55 82 112 72 226 227 69 329 77 57 28 34 0 0 0 1 0 0 1 0 0 32 0 0 0 53 COG1521(Putative transcriptional regulator, homolog of Bvg accessory factor) 162 112 112 149 23 21 42 62 43 14 15 32 31 59 31 35 69 80 43 56 70 65 117 64 64 125 72 89 63 17 44 126 78 68 247 242 48 269 89 86 39 20 0 0 0 0 0 0 1 0 0 42 0 0 0 65 COG0054(Riboflavin synthase beta-chain) 178 141 148 171 16 15 61 50 24 34 19 35 15 39 41 37 39 69 52 57 40 68 113 58 81 120 39 60 50 21 68 97 104 74 210 287 52 326 58 79 23 47 0 0 1 0 0 0 2 0 2 34 0 0 0 42 COG4531(ABC-type Zn2+ transport system, periplasmic component/surface adhesin) 162 200 173 234 1 14 61 54 22 28 11 17 14 45 19 21 6 2 30 75 72 85 111 76 87 1 71 63 80 4 67 127 123 88 258 208 53 227 101 68 24 46 0 0 0 0 0 0 0 0 2 46 0 2 0 106 COG0737(5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases) 559 95 187 121 24 29 42 11 20 15 20 10 4 68 26 16 46 69 43 27 40 55 112 41 53 115 42 37 32 14 10 65 66 40 152 133 46 744 35 40 18 23 0 0 0 0 0 0 0 0 0 13 0 0 0 26 NOG20081() 213 149 115 160 21 15 68 44 22 17 19 22 40 30 28 40 55 43 49 67 100 73 136 82 86 58 51 73 60 43 63 120 72 58 191 242 51 250 118 74 30 55 0 1 0 0 1 0 2 0 0 23 0 0 1 52 COG0139(Phosphoribosyl-AMP cyclohydrolase) 339 158 138 141 17 13 45 76 26 20 10 27 4 38 39 43 55 59 40 58 51 39 99 72 52 69 60 67 55 14 60 104 86 58 187 272 59 370 68 53 25 33 0 0 2 0 1 0 0 0 0 25 0 1 0 53 COG1252(NADH dehydrogenase, FAD-containing subunit) 417 56 67 92 21 18 49 18 9 17 12 9 15 66 31 14 64 96 37 23 66 63 130 81 60 134 31 51 88 60 73 87 58 47 91 108 25 752 110 35 25 29 0 1 0 0 0 0 2 0 0 26 0 1 0 16 COG0637(Predicted phosphatase/phosphohexomutase) 395 93 71 91 21 31 46 31 23 26 13 37 11 50 16 26 40 62 27 51 52 42 93 54 85 140 44 50 53 29 36 88 78 51 124 174 59 733 59 44 21 24 0 0 2 0 0 0 0 0 0 24 0 0 0 59 COG3497(Phage tail sheath protein FI) 18 35 55 32 3 2 20 146 27 40 102 19 57 44 13 32 33 65 55 71 39 70 184 99 80 424 102 82 148 147 59 96 78 72 78 120 27 170 80 54 53 44 2 1 0 0 2 2 2 0 0 31 0 0 1 158 COG1496(Uncharacterized conserved protein) 222 133 155 180 7 21 63 53 21 19 20 25 19 55 22 34 47 78 32 55 72 56 109 73 83 94 50 62 60 15 58 86 104 55 222 254 81 271 73 71 27 35 0 2 0 0 0 0 1 3 0 32 0 0 0 49 COG0319(Predicted metal-dependent hydrolase) 180 135 170 154 24 11 42 65 19 33 19 25 17 47 48 38 67 65 37 56 76 52 117 61 79 126 55 51 56 18 43 104 107 65 218 214 70 328 64 87 28 28 0 0 0 0 0 0 2 1 2 20 0 0 0 34 COG0647(Predicted sugar phosphatases of the HAD superfamily) 139 122 142 174 13 11 66 48 22 19 16 30 19 70 37 42 45 47 41 57 62 74 107 60 55 68 67 85 63 18 46 119 127 99 217 297 38 256 57 84 37 44 0 1 0 0 2 0 0 0 0 26 0 0 0 85 COG0475(Kef-type K+ transport systems, membrane components) 381 69 109 86 12 19 19 23 7 6 13 16 16 66 17 26 67 60 34 49 66 50 124 79 82 70 53 50 45 21 62 52 45 48 64 106 152 845 94 27 26 34 0 0 0 0 0 0 1 0 0 24 0 0 1 38 COG0261(Ribosomal protein L21) 148 147 152 173 24 14 58 58 28 24 19 31 18 49 13 22 59 80 49 57 66 60 114 72 66 87 63 65 53 17 67 118 87 76 244 235 49 289 69 83 30 30 0 0 2 1 0 1 1 2 0 31 0 1 0 47 COG1117(ABC-type phosphate transport system, ATPase component) 254 218 169 234 9 15 71 38 27 8 30 7 17 61 33 36 74 87 43 97 113 97 186 102 103 181 51 35 41 32 36 57 25 15 67 34 27 487 24 16 12 8 0 0 0 0 0 0 0 0 0 8 0 0 0 63 COG2022(Uncharacterized enzyme of thiazole biosynthesis) 315 155 139 179 10 16 39 27 15 21 35 29 20 60 36 46 28 52 51 53 68 65 126 85 69 83 71 61 66 31 84 91 75 64 176 243 75 223 77 55 26 34 0 0 0 0 0 1 0 1 0 25 3 0 0 43 COG0089(Ribosomal protein L23) 127 123 155 152 8 16 51 58 20 18 13 30 19 62 52 34 78 56 32 75 58 70 112 67 74 128 71 69 67 14 45 116 93 68 191 234 52 327 71 95 38 23 0 0 1 0 0 0 1 0 0 35 0 0 0 47 COG0705(Uncharacterized membrane protein (homolog of Drosophila rhomboid)) 178 110 182 110 38 17 38 32 25 34 18 21 33 50 32 30 62 68 43 46 44 58 100 41 53 124 86 66 36 25 35 100 96 73 186 235 65 433 45 108 45 39 0 0 0 0 1 1 0 0 2 25 0 0 0 55 COG0695(Glutaredoxin and related proteins) 206 160 133 130 11 21 31 59 33 35 34 42 29 40 55 37 63 54 54 54 75 55 101 66 69 104 45 84 71 37 69 109 103 54 179 180 82 280 82 65 27 24 0 0 0 0 0 0 0 0 0 37 1 0 0 63 COG1116(ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component) 770 69 70 85 15 41 21 40 12 6 16 15 23 73 29 19 83 63 45 28 42 39 82 59 49 173 70 26 39 15 35 58 44 34 113 104 40 650 28 39 20 6 0 0 0 0 0 0 1 0 0 21 0 0 0 33 COG1210(UDP-glucose pyrophosphorylase) 280 165 134 170 8 9 49 57 31 18 21 25 10 36 36 26 63 53 31 56 48 66 96 64 61 121 52 59 48 17 51 98 68 72 224 231 70 319 51 72 33 39 0 0 0 0 0 2 0 0 0 27 0 0 1 68 COG1429(Cobalamin biosynthesis protein CobN and related Mg-chelatases) 266 71 58 147 26 50 21 23 6 13 16 9 14 63 34 9 25 11 32 32 122 51 201 122 156 42 42 44 92 109 112 124 90 53 172 60 11 468 123 62 22 46 0 2 0 0 2 0 0 4 0 38 0 2 0 36 COG0663(Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily) 288 169 167 159 16 19 54 74 23 38 26 31 18 71 35 31 30 36 41 61 58 50 107 66 63 90 70 52 49 10 57 81 76 64 238 177 48 310 69 62 33 28 1 0 1 0 2 0 0 0 0 35 0 0 1 49 COG3023(Negative regulator of beta-lactamase expression) 259 168 171 145 3 10 42 61 24 27 35 47 21 117 19 47 43 24 49 74 46 39 91 61 59 46 50 50 49 22 47 86 91 57 202 239 74 386 44 59 32 33 0 0 1 0 1 0 1 2 0 25 0 0 0 52 COG2896(Molybdenum cofactor biosynthesis enzyme) 301 136 169 112 8 25 20 48 28 27 23 39 24 74 41 33 54 67 49 71 53 63 110 47 29 121 68 64 34 12 19 85 89 54 167 266 82 296 66 73 45 31 0 0 0 1 0 0 0 1 0 30 2 0 0 66 COG0293(23S rRNA methylase) 185 198 166 191 18 21 54 69 32 25 25 30 12 38 45 41 58 47 51 61 41 41 120 54 67 32 65 54 58 23 40 111 110 60 242 288 60 182 59 81 34 32 0 0 0 0 2 0 0 0 0 39 0 0 0 61 COG0198(Ribosomal protein L24) 145 182 141 157 20 20 43 42 21 27 15 23 14 49 34 40 87 51 40 61 51 57 96 71 54 151 43 60 56 19 56 87 95 80 182 234 74 321 75 74 30 53 0 0 0 3 2 0 0 0 0 34 1 0 0 50 COG0579(Predicted dehydrogenase) 348 90 142 105 19 12 50 39 20 14 23 26 20 60 49 31 52 72 48 70 77 40 126 71 88 129 57 58 58 38 56 87 60 46 116 213 54 385 73 51 41 22 0 0 0 0 0 0 1 0 0 34 0 1 0 44 COG0199(Ribosomal protein S14) 174 159 152 134 23 17 54 44 20 33 25 25 13 43 32 38 83 70 36 57 60 51 94 69 55 118 64 64 53 22 52 96 96 75 221 228 54 291 77 82 23 49 0 0 0 0 1 0 0 0 0 39 0 0 0 47 COG2154(Pterin-4a-carbinolamine dehydratase) 200 195 196 170 19 25 43 66 25 20 14 30 28 76 42 24 34 46 32 59 67 57 104 63 65 76 54 65 69 25 36 116 104 45 225 217 44 225 57 91 31 37 0 1 0 0 0 0 0 0 0 29 0 0 0 58 COG1381(Recombinational DNA repair protein (RecF pathway)) 216 157 177 179 8 9 38 66 16 21 26 37 14 42 23 26 84 78 37 45 53 59 99 43 61 141 47 38 39 10 47 94 63 58 189 236 69 409 58 61 24 31 1 1 0 1 0 0 0 0 0 26 0 2 1 43 COG1793(ATP-dependent DNA ligase) 620 90 116 124 21 31 18 62 33 38 30 17 52 32 13 10 23 25 34 67 65 34 123 60 67 92 37 40 68 53 78 111 62 45 108 79 102 413 49 51 28 24 0 1 2 0 0 1 0 0 0 27 0 2 0 22 COG0350(Methylated DNA-protein cysteine methyltransferase) 444 135 179 133 6 14 42 36 19 30 17 17 11 58 32 34 62 64 45 60 60 47 82 60 54 127 47 35 49 11 38 77 75 88 157 227 65 331 49 47 31 27 0 0 0 0 2 0 0 1 0 26 1 0 0 46 COG3639(ABC-type phosphate/phosphonate transport system, permease component) 250 136 96 157 17 46 100 20 12 3 0 9 8 19 38 31 31 10 18 44 89 66 179 96 107 40 49 42 37 46 45 72 66 62 68 109 14 854 58 42 13 16 0 1 0 0 1 0 0 0 0 28 0 0 0 53 COG0858(Ribosome-binding factor A) 184 165 145 175 17 13 50 56 27 23 33 33 13 32 24 42 54 72 39 52 66 71 104 69 77 112 49 55 50 21 48 105 103 63 250 185 61 283 74 80 23 33 0 0 0 1 0 1 0 0 0 29 1 0 0 35 COG3836(2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase) 266 171 162 167 20 23 60 50 19 22 21 20 14 70 33 44 45 37 40 72 75 63 120 78 56 53 62 62 58 15 40 102 84 82 217 223 48 176 66 74 49 41 0 1 0 0 0 0 0 0 0 43 0 0 0 53 COG2301(Citrate lyase beta subunit) 357 152 120 160 6 30 45 46 24 26 21 20 28 78 28 23 61 38 46 43 37 54 117 59 65 73 51 44 42 2 50 94 80 65 191 248 43 337 52 72 41 36 0 1 0 0 0 0 0 0 0 43 0 0 0 36 COG0809(S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)) 194 134 207 126 26 28 36 43 30 40 14 17 20 72 47 42 52 49 40 48 50 59 148 60 75 79 49 61 70 28 43 115 51 46 198 175 70 341 77 73 34 45 0 3 0 0 0 1 0 0 0 29 0 0 0 38 COG1485(Predicted ATPase) 251 156 150 121 13 19 60 57 19 18 22 34 17 66 41 33 51 61 50 70 40 53 84 50 53 34 59 68 52 13 33 96 143 88 215 136 70 398 53 71 35 36 0 0 1 0 0 1 0 0 0 23 1 0 2 62 COG0688(Phosphatidylserine decarboxylase) 270 151 170 160 12 12 37 64 25 24 20 42 24 57 63 42 67 57 56 51 45 77 96 68 41 69 62 47 55 10 47 93 105 82 209 277 49 135 60 71 54 39 0 0 0 0 0 1 0 1 0 30 0 0 0 44 COG1738(Uncharacterized conserved protein) 151 165 145 153 23 13 70 62 30 19 20 32 9 40 37 24 59 58 50 74 60 69 99 82 53 90 49 62 59 15 57 122 106 76 265 251 55 164 52 93 33 34 0 0 0 0 1 0 2 1 0 25 0 0 0 61 COG0799(Uncharacterized homolog of plant Iojap protein) 163 180 172 165 22 15 47 53 16 14 20 26 20 41 40 35 42 46 47 43 70 66 95 65 58 137 54 66 62 10 44 117 90 67 211 236 62 279 58 70 30 39 0 0 0 0 1 0 1 0 0 27 0 0 1 35 COG0186(Ribosomal protein S17) 129 169 140 175 22 14 48 51 26 21 11 31 25 53 28 39 50 47 34 64 52 54 98 76 74 144 42 53 61 21 70 82 100 82 196 207 62 306 65 81 28 30 0 0 0 1 1 0 0 0 0 38 0 0 0 51 COG0227(Ribosomal protein L28) 170 155 147 133 21 15 46 63 25 13 17 17 14 45 46 27 59 55 40 73 60 68 105 79 81 75 51 86 56 12 48 97 96 83 210 253 50 302 46 82 27 31 0 1 0 0 0 0 3 2 0 28 0 0 0 38 COG1064(Zn-dependent alcohol dehydrogenases) 284 147 114 112 6 18 47 48 35 61 38 44 17 71 64 48 59 55 53 63 40 35 73 49 54 101 81 44 37 13 31 78 74 49 212 147 51 422 57 74 36 46 0 0 0 0 0 1 0 0 0 21 0 1 0 39 COG1596(Periplasmic protein involved in polysaccharide export) 543 158 279 133 22 10 37 23 29 15 20 18 24 23 30 30 16 25 37 32 51 60 91 48 59 70 52 32 40 23 47 89 73 66 231 153 51 253 58 90 24 29 0 1 0 0 2 0 0 2 0 17 0 1 2 31 COG1610(Uncharacterized conserved protein) 152 166 192 139 16 19 52 56 37 21 26 27 14 43 34 34 64 69 40 52 39 39 122 51 58 109 63 80 41 13 54 112 96 88 207 277 66 167 57 88 30 44 0 1 0 0 1 0 0 0 0 34 0 0 0 58 COG1898(dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes) 356 82 132 106 15 5 37 76 40 13 21 32 26 51 28 27 73 63 40 34 56 41 82 50 59 160 41 53 46 14 44 97 71 84 157 199 45 428 62 65 31 38 1 0 0 0 0 2 0 0 0 22 0 0 0 41 COG0360(Ribosomal protein S6) 151 134 159 167 11 12 45 33 37 15 19 23 17 31 36 34 64 72 39 46 66 61 104 66 78 125 56 46 55 12 64 91 91 76 241 210 60 303 66 78 37 42 0 0 0 0 0 1 0 0 2 28 1 0 0 39 COG0670(Integral membrane protein, interacts with FtsH) 227 158 128 178 12 17 48 70 26 20 20 22 24 24 37 36 32 42 39 79 66 60 107 56 83 64 48 58 53 24 78 93 117 76 197 285 51 179 53 82 46 19 0 2 2 0 0 0 0 0 0 43 0 0 0 59 COG1459(Type II secretory pathway, component PulF) 606 121 213 127 11 16 24 50 14 28 18 37 13 42 34 14 50 26 39 30 40 50 93 70 57 90 64 46 56 22 45 73 44 35 145 120 160 323 52 37 7 22 0 0 0 0 0 0 0 0 0 31 0 1 0 42 COG1694(Predicted pyrophosphatase) 127 93 137 81 17 14 42 61 22 21 40 20 19 60 30 22 48 71 55 52 87 51 127 62 57 167 57 73 90 83 48 91 74 76 155 141 35 413 87 59 43 36 0 0 1 0 0 0 0 0 2 22 1 0 0 66 COG0597(Lipoprotein signal peptidase) 239 142 156 156 9 13 40 56 22 20 16 36 22 42 39 32 60 66 38 62 65 46 108 75 57 106 50 58 53 15 65 96 76 46 153 230 41 332 66 62 36 40 0 0 0 0 0 0 1 0 0 30 1 0 0 61 COG0785(Cytochrome c biogenesis protein) 349 119 101 142 2 14 47 50 15 24 11 25 13 54 23 31 71 70 35 58 68 41 85 61 58 134 65 75 52 22 57 108 63 68 181 219 68 281 56 48 43 25 0 0 0 0 1 3 2 1 0 30 0 0 0 66 COG3653(N-acyl-D-aspartate/D-glutamate deacylase) 187 112 284 152 20 17 30 26 32 34 22 20 32 134 57 41 46 39 82 69 61 98 123 33 53 153 61 49 39 17 37 107 63 37 138 229 38 244 60 45 25 25 0 0 0 0 0 0 0 0 0 28 0 2 0 29 COG0509(Glycine cleavage system H protein (lipoate-binding)) 137 132 138 139 10 18 45 66 22 20 20 27 24 59 27 41 59 61 40 72 64 73 107 91 68 129 67 56 57 9 46 105 86 71 206 177 53 292 75 71 38 28 0 0 0 0 0 2 0 1 2 33 0 1 0 59 COG0822(NifU homolog involved in Fe-S cluster formation) 151 179 158 163 7 15 41 73 28 19 39 36 16 44 52 39 71 58 31 57 46 45 98 68 51 213 56 49 63 15 40 98 90 86 198 241 73 153 48 78 23 28 0 0 1 0 2 0 4 1 0 34 0 0 0 45 COG5524(Bacteriorhodopsin) 111 159 187 151 17 12 65 59 25 27 24 40 37 69 31 38 62 57 44 85 71 73 98 49 74 122 62 53 47 7 40 113 104 75 200 187 27 215 60 80 29 30 0 0 0 0 0 0 1 0 0 30 0 1 0 68 COG3491(Isopenicillin N synthase and related dioxygenases) 149 159 255 181 26 20 46 46 35 23 20 19 19 67 31 37 25 38 59 73 61 70 112 68 65 96 95 58 31 21 43 120 109 85 227 207 39 76 46 98 44 27 0 0 0 0 0 0 0 0 2 27 0 0 0 61 COG1409(Predicted phosphohydrolases) 488 152 187 130 25 31 48 21 12 11 30 4 10 59 21 11 14 24 39 40 51 63 65 31 30 46 35 28 25 49 24 123 90 69 215 118 58 458 86 70 31 39 0 2 0 0 0 0 0 0 0 17 0 0 2 29 COG0352(Thiamine monophosphate synthase) 294 150 133 169 13 24 42 40 13 24 18 30 13 44 34 23 58 42 35 49 54 44 116 62 78 35 45 60 54 24 42 91 94 57 203 207 60 358 69 50 26 31 0 0 1 0 0 0 0 0 0 44 0 0 2 46 COG1999(Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems) 363 175 228 136 24 17 53 51 21 24 32 33 18 63 29 15 19 28 47 51 49 55 101 54 67 37 61 47 39 18 27 91 85 52 182 239 46 276 40 67 28 55 1 0 0 1 1 0 1 0 0 28 0 0 0 24 NOG05996() 160 190 138 179 6 16 51 85 37 35 30 43 13 55 30 41 21 15 32 57 37 38 103 48 43 9 78 43 63 2 57 118 112 81 265 390 44 131 81 60 23 41 0 1 0 1 1 0 0 0 0 30 0 0 0 64 COG0254(Ribosomal protein L31) 185 144 169 148 16 17 61 48 25 13 14 26 26 76 31 43 52 47 34 57 79 62 102 58 65 98 53 58 50 20 45 85 91 65 220 238 60 253 43 74 37 22 0 0 0 1 0 0 0 0 2 32 1 1 0 51 COG1360(Flagellar motor protein) 529 81 149 77 22 12 29 49 24 28 40 9 7 97 25 23 22 11 52 41 39 54 95 62 56 39 45 64 48 5 36 89 64 71 178 118 49 465 52 121 25 25 0 0 0 0 0 0 0 2 0 26 0 1 0 37 COG4642(Uncharacterized protein conserved in bacteria) 76 206 303 219 35 72 42 59 30 31 24 35 29 38 54 33 21 23 58 52 58 71 123 65 90 14 71 85 38 63 32 73 75 60 147 307 38 89 61 67 17 26 0 1 0 1 0 2 0 2 0 23 1 0 0 49 COG2009(Succinate dehydrogenase/fumarate reductase, cytochrome b subunit) 234 159 140 160 10 15 35 56 21 15 18 44 16 34 33 39 51 39 45 58 48 38 87 70 62 28 60 61 69 7 59 92 94 71 235 249 43 302 46 66 35 35 2 2 1 2 0 0 0 0 0 34 0 0 0 60 COG1539(Dihydroneopterin aldolase) 221 125 136 126 19 10 60 63 30 23 17 31 19 63 43 31 52 56 39 67 78 57 99 43 67 69 72 61 53 15 39 84 97 66 240 222 63 248 72 85 33 18 0 0 0 0 0 0 0 1 0 22 0 0 0 42 COG3178(Predicted phosphotransferase related to Ser/Thr protein kinases) 226 197 165 217 10 11 52 69 15 30 34 27 23 46 29 49 46 53 32 78 56 65 82 59 70 82 61 48 58 10 41 114 77 54 213 267 66 80 54 66 27 27 0 0 0 0 0 0 2 0 0 34 0 2 0 53 NOG06309() 139 147 117 191 0 19 57 79 25 6 21 39 16 29 38 40 49 32 21 54 59 54 103 61 63 47 93 68 55 4 53 112 114 80 284 339 61 58 57 88 47 35 0 0 0 0 0 0 0 1 0 32 0 0 0 77 NOG20591() 131 147 138 206 0 1 23 129 32 98 37 48 28 18 31 10 19 13 14 46 104 94 139 144 94 14 122 91 75 5 80 25 32 56 196 250 27 129 53 29 33 49 0 0 0 0 3 0 0 0 0 48 1 4 4 89 COG1327(Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains) 196 156 129 146 11 13 48 42 16 23 24 28 16 40 25 27 63 71 36 46 59 33 97 75 74 110 49 63 60 15 53 95 83 60 201 252 64 318 49 59 33 31 0 0 0 0 0 2 0 0 0 23 0 0 0 45 COG0207(Thymidylate synthase) 160 126 163 122 19 24 47 72 31 30 63 28 45 69 38 40 52 83 71 55 43 63 102 36 44 164 43 42 43 34 21 92 89 64 195 196 83 205 46 62 36 40 0 0 0 0 0 0 0 3 0 32 0 0 1 38 COG1301(Na+/H+-dicarboxylate symporters) 923 130 200 115 31 21 43 36 22 22 24 10 14 64 25 26 33 26 37 40 42 36 93 41 38 58 23 46 21 25 16 76 67 31 159 148 55 150 21 43 34 28 0 0 0 0 4 0 0 1 0 25 0 2 0 21 COG4618(ABC-type protease/lipase transport system, ATPase and permease components) 405 109 87 98 5 13 28 40 8 22 12 17 13 67 11 24 44 63 56 46 41 57 65 52 55 131 34 35 33 6 33 71 78 52 131 157 43 670 50 81 34 16 2 0 0 0 0 0 0 0 0 14 0 0 0 36 COG0860(N-acetylmuramoyl-L-alanine amidase) 256 108 180 103 27 15 35 24 26 28 13 20 26 53 27 32 96 59 42 46 57 39 105 52 63 127 48 47 49 30 44 102 67 61 189 183 49 353 47 82 16 33 0 0 1 1 3 0 0 0 0 37 0 0 0 40 COG2908(Uncharacterized protein conserved in bacteria) 311 273 272 208 32 37 110 20 19 17 6 22 18 29 18 21 41 46 37 63 71 78 174 84 87 165 22 29 31 8 20 59 51 24 139 113 24 206 32 41 20 16 0 0 0 0 1 0 0 2 0 23 0 0 0 13 COG0400(Predicted esterase) 250 144 118 194 18 21 48 46 17 21 15 30 18 27 37 22 43 33 34 51 51 58 126 64 67 31 34 64 67 19 70 108 86 66 193 260 34 254 68 63 40 33 0 0 0 0 0 0 0 0 0 33 0 0 0 56 COG2040(Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)) 146 159 156 182 9 20 45 78 27 19 26 37 22 60 33 43 22 21 49 67 51 54 98 62 81 32 58 57 65 9 35 96 86 66 214 267 33 241 70 74 30 38 0 0 2 0 0 0 0 0 0 35 0 0 0 50 COG1574(Predicted metal-dependent hydrolase with the TIM-barrel fold) 392 73 276 75 22 14 25 48 46 14 52 29 36 101 37 32 40 33 65 27 39 37 56 33 25 61 49 33 31 5 18 87 48 46 121 221 37 560 27 62 24 24 0 0 0 0 0 0 0 0 0 15 2 1 0 19 COG1611(Predicted Rossmann fold nucleotide-binding protein) 429 107 160 122 16 20 39 14 25 28 18 22 16 44 31 19 62 63 48 38 59 31 98 49 59 172 29 35 43 18 35 71 58 37 180 159 97 335 69 72 15 21 0 0 0 2 0 0 2 0 0 18 1 0 0 30 COG0838(NADH:ubiquinone oxidoreductase subunit 3 (chain A)) 163 154 171 161 7 11 52 46 22 29 7 24 28 102 32 40 81 65 30 58 57 69 99 64 66 152 59 68 64 13 42 90 73 73 146 235 16 140 66 57 34 31 0 0 2 1 0 0 3 0 0 32 1 0 2 71 COG2853(Surface lipoprotein) 249 182 185 163 10 10 41 49 24 22 20 30 16 70 26 43 30 47 40 69 46 45 103 69 64 29 48 54 57 3 37 113 83 89 220 242 52 205 49 52 32 15 0 0 0 0 2 0 0 2 0 26 1 0 0 44 COG0528(Uridylate kinase) 168 98 171 96 19 15 40 30 17 28 16 11 15 48 34 32 55 60 43 58 43 59 89 59 79 156 60 61 61 22 36 101 77 62 138 166 74 428 44 95 30 40 1 0 0 0 0 0 0 0 0 29 0 0 0 41 COG0412(Dienelactone hydrolase and related enzymes) 542 80 161 107 18 11 41 43 16 17 21 13 15 79 39 41 85 80 61 48 51 48 107 47 70 134 48 34 56 10 21 48 44 41 100 201 43 294 46 56 17 15 2 2 0 0 0 0 0 0 2 15 0 1 0 33 COG1199(Rad3-related DNA helicases) 392 49 161 78 28 19 18 28 12 22 23 22 27 70 35 32 76 94 62 30 51 45 98 58 41 310 41 21 47 53 49 52 54 41 71 71 87 452 49 47 14 21 0 1 0 0 0 0 1 0 0 22 0 0 0 25 COG0211(Ribosomal protein L27) 137 161 145 149 19 21 52 38 24 29 13 25 23 46 21 22 49 62 43 74 54 50 112 75 56 87 50 63 59 22 53 106 93 72 196 226 35 267 57 63 30 42 2 0 1 0 0 0 0 2 0 30 0 0 0 36 COG2895(GTPases - Sulfate adenylate transferase subunit 1) 428 70 84 74 20 26 38 50 25 23 39 15 24 82 12 25 67 67 42 49 60 38 49 46 56 218 40 22 38 12 27 71 69 54 123 100 70 516 82 32 20 14 0 0 0 0 2 0 0 0 0 27 0 0 0 40 COG0619(ABC-type cobalt transport system, permease component CbiQ and related transporters) 287 61 70 70 6 8 32 24 25 21 10 19 20 26 25 32 78 73 45 48 58 61 109 55 60 214 48 53 49 19 40 62 41 60 103 137 45 606 95 59 24 18 0 0 0 0 0 0 1 0 2 27 0 0 0 60 COG1670(Acetyltransferases, including N-acetylases of ribosomal proteins) 789 59 97 62 7 15 11 26 21 15 23 12 14 45 36 39 96 86 51 44 38 25 71 34 33 195 34 28 18 7 14 48 30 58 81 148 64 454 24 42 8 19 0 0 0 0 0 0 3 0 0 18 1 0 0 41 COG3090(TRAP-type C4-dicarboxylate transport system, small permease component) 284 114 93 111 8 13 54 78 37 54 24 40 41 56 29 33 69 66 41 51 42 33 97 56 49 97 61 55 55 4 63 82 78 55 154 150 32 345 50 80 28 42 2 0 1 2 0 0 1 0 0 36 2 0 0 36 COG1234(Metal-dependent hydrolases of the beta-lactamase superfamily III) 103 173 194 145 25 23 47 35 19 23 14 25 20 68 34 25 36 21 55 49 57 62 149 58 85 45 62 72 78 46 61 131 111 57 198 215 43 112 50 95 36 37 0 2 0 0 0 3 0 0 0 32 1 0 0 52 COG1758(DNA-directed RNA polymerase, subunit K/omega) 183 124 133 129 17 12 49 51 21 22 12 41 12 38 46 31 56 50 49 80 63 47 116 71 76 95 59 50 47 13 51 86 76 56 206 247 63 240 75 53 26 27 1 0 0 0 0 0 2 3 0 25 0 0 0 50 COG1083(CMP-N-acetylneuraminic acid synthetase) 95 127 187 166 8 13 30 67 16 14 14 21 15 47 19 16 31 43 55 43 66 59 126 61 61 113 55 72 42 11 54 101 93 85 210 257 83 272 55 63 26 24 0 0 0 1 0 0 1 0 0 23 0 1 0 34 COG1866(Phosphoenolpyruvate carboxykinase (ATP)) 140 198 201 115 14 20 61 39 27 32 27 47 22 62 40 31 5 17 42 51 53 67 123 53 55 35 57 61 55 29 43 92 89 49 200 214 32 242 62 95 42 41 0 0 0 0 0 0 0 0 0 35 0 0 0 47 NOG05075() 70 110 91 142 2 9 33 121 27 41 41 39 32 55 49 43 25 43 89 87 60 59 141 80 54 127 42 76 103 96 67 98 104 63 157 198 14 45 82 49 38 31 0 0 0 0 0 0 0 0 0 39 0 0 0 77 COG1729(Uncharacterized protein conserved in bacteria) 190 191 177 186 4 6 52 62 14 40 24 28 15 39 19 47 46 40 38 49 55 46 85 60 54 50 68 44 58 6 54 102 111 69 213 251 48 173 50 63 24 27 0 0 0 0 0 0 0 0 1 15 0 0 2 45 COG5184(Alpha-tubulin suppressor and related RCC1 domain-containing proteins) 15 51 124 42 30 61 7 69 79 17 15 20 55 43 24 23 40 41 37 52 60 81 100 41 35 333 54 54 44 108 9 103 140 34 14 164 32 457 39 97 73 33 0 0 0 0 0 0 0 0 0 23 0 0 0 64 COG1256(Flagellar hook-associated protein) 530 44 55 58 8 21 27 46 17 18 33 15 24 45 24 23 15 23 45 36 26 65 75 44 33 30 46 67 51 25 34 113 178 51 73 57 33 550 64 88 75 52 0 0 0 0 0 0 2 0 0 20 0 0 1 70 COG3572(Gamma-glutamylcysteine synthetase) 196 148 148 153 7 20 60 52 10 19 12 37 17 34 42 33 40 39 36 54 62 55 102 72 75 39 63 65 63 1 48 110 105 107 248 168 55 111 55 70 38 43 0 1 0 2 0 1 1 0 1 41 0 2 0 69 COG1494(Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins) 118 120 113 142 4 10 32 42 17 20 12 30 10 48 50 23 59 48 26 54 76 82 110 68 67 125 41 52 52 21 67 102 94 66 200 228 52 265 51 88 30 25 0 0 0 0 0 0 3 0 0 24 0 0 0 55 COG2872(Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain) 316 139 157 115 4 17 53 50 11 25 16 13 21 35 29 44 27 37 39 37 47 51 87 56 64 121 30 44 37 10 35 76 50 43 117 106 32 642 49 46 24 24 0 0 0 0 0 0 0 0 0 20 0 0 0 25 COG4525(ABC-type taurine transport system, ATPase component) 553 131 91 137 2 12 54 63 16 9 15 35 18 34 23 37 29 37 21 45 56 58 76 48 37 50 63 57 48 4 43 84 106 105 183 251 56 85 60 64 24 31 0 0 0 0 0 0 1 0 0 26 1 0 0 41 COG0236(Acyl carrier protein) 416 117 131 133 14 15 35 37 19 23 12 22 21 49 38 39 24 31 30 52 65 50 75 59 59 71 48 57 48 12 39 96 83 62 181 181 24 277 63 63 30 33 0 0 0 0 1 1 1 0 0 23 0 1 0 56 COG1734(DnaK suppressor protein) 148 178 154 173 4 12 46 55 19 26 18 31 13 36 41 36 50 70 37 64 44 60 93 64 62 92 70 56 51 3 30 101 75 59 197 223 71 225 49 47 27 19 0 0 1 0 0 0 0 0 0 23 0 1 0 59 COG0752(Glycyl-tRNA synthetase, alpha subunit) 219 159 95 160 10 7 40 56 23 31 23 31 17 64 38 49 51 54 48 54 72 44 114 69 72 44 44 65 58 24 64 60 91 49 189 205 68 201 55 55 38 35 1 1 1 1 0 0 0 0 0 15 0 0 0 43 COG4985(ABC-type phosphate transport system, auxiliary component) 215 220 224 251 5 16 99 21 1 11 10 4 10 34 19 62 57 68 37 142 119 108 167 121 135 63 33 18 19 9 19 11 19 3 20 34 10 500 18 11 10 4 0 0 0 0 0 0 0 2 0 3 1 0 0 44 COG0762(Predicted integral membrane protein) 208 167 120 174 8 16 34 30 16 30 11 16 13 35 17 37 52 68 34 43 64 56 137 57 55 58 34 35 54 30 66 117 95 54 207 179 48 280 57 57 29 36 0 0 0 1 0 0 0 2 0 29 0 0 0 33 COG4886(Leucine-rich repeat (LRR) protein) 252 73 216 129 118 155 8 36 69 15 19 18 20 60 30 31 101 89 63 28 50 59 82 44 41 161 41 33 24 172 30 45 24 41 39 87 122 259 16 48 14 6 0 0 0 0 0 0 0 0 0 14 0 0 1 10 COG1080(Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)) 374 58 62 69 3 13 43 35 15 19 14 15 5 28 43 46 62 65 33 54 70 52 59 40 37 87 36 64 51 2 30 60 77 44 93 135 48 712 68 27 26 20 0 0 0 0 0 0 0 0 1 22 0 0 0 74 COG4625(Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain) 1629 40 104 29 4 11 3 41 21 24 9 7 25 18 8 13 33 36 8 17 14 21 34 27 30 48 18 27 27 19 15 16 16 2 12 34 21 437 17 20 1 2 0 0 0 0 0 0 0 0 0 10 0 0 0 39 COG0759(Uncharacterized conserved protein) 148 134 150 162 20 17 46 52 16 19 17 26 10 53 36 27 48 48 33 44 63 49 114 56 63 120 40 59 47 19 38 67 88 57 223 222 40 275 51 52 27 33 0 1 0 0 0 0 1 0 0 21 0 1 0 42 COG2255(Holliday junction resolvasome, helicase subunit) 148 61 149 77 37 13 24 41 29 11 29 16 22 77 21 16 77 66 42 24 39 65 90 49 64 152 50 39 43 20 37 67 52 39 129 153 96 596 52 52 19 14 0 0 0 0 1 1 0 0 0 32 2 0 0 30 COG3979(Uncharacterized protein contain chitin-binding domain type 3) 696 56 176 53 26 7 28 19 16 22 27 16 8 30 10 11 27 14 19 35 32 98 95 36 38 99 50 42 36 11 39 47 62 32 98 85 93 365 51 106 30 28 0 0 0 0 6 0 0 0 0 15 0 0 0 64 COG5598(Trimethylamine:corrinoid methyltransferase) 67 65 114 86 11 30 18 32 33 29 20 18 23 141 46 31 31 45 117 79 28 34 55 59 35 112 62 51 34 9 24 129 85 87 236 273 32 175 82 117 37 54 0 1 2 2 0 0 0 0 0 48 0 0 0 51 COG3962(Acetolactate synthase) 209 144 139 146 6 10 42 47 17 20 13 20 21 46 39 48 47 20 42 67 49 75 95 76 73 36 72 76 56 3 68 110 96 92 216 191 53 80 67 66 28 31 0 0 0 1 2 0 0 0 0 33 1 0 1 59 COG2236(Predicted phosphoribosyltransferases) 167 192 144 186 6 12 45 64 13 14 15 29 14 57 25 56 49 43 18 71 56 47 103 62 51 63 54 55 30 9 44 99 118 89 238 227 45 75 58 58 27 24 0 0 0 0 1 0 0 1 0 28 0 0 0 61 COG4341(Predicted HD phosphohydrolase) 152 198 156 207 10 10 57 57 15 14 15 9 6 53 24 33 31 32 49 66 47 55 95 59 67 38 47 57 38 6 47 68 75 79 195 323 58 142 61 62 25 34 2 0 0 0 0 0 0 0 0 30 1 1 0 36 COG1388(FOG: LysM repeat) 517 87 120 74 45 18 28 38 16 19 25 8 22 60 20 17 56 33 43 35 41 34 79 28 37 111 18 58 36 23 32 97 50 47 145 153 32 393 62 69 22 28 0 0 1 0 2 0 0 0 0 32 0 0 0 30 COG0347(Nitrogen regulatory protein PII) 396 102 103 104 12 27 36 46 25 37 30 28 19 72 32 31 54 44 33 39 57 39 83 46 63 140 55 52 49 24 35 94 64 43 168 116 57 277 49 46 23 24 0 0 0 0 0 0 0 0 0 31 0 1 1 31 COG1959(Predicted transcriptional regulator) 298 164 158 144 10 6 35 65 28 26 18 29 19 37 27 23 44 42 26 41 37 50 87 54 59 63 36 50 44 12 58 73 78 48 154 172 63 343 50 61 24 17 2 3 0 0 0 0 0 0 0 21 0 0 0 36 COG0385(Predicted Na+-dependent transporter) 248 122 121 154 5 21 54 47 21 13 21 24 14 21 38 25 23 39 30 56 38 67 99 44 72 8 51 69 47 11 54 108 111 80 197 252 27 207 83 47 40 30 0 2 0 0 0 0 0 0 0 33 0 0 0 56 NOG09978() 17 35 97 36 65 61 28 78 51 66 49 41 48 61 30 28 35 60 104 37 37 50 82 33 67 41 54 94 31 46 45 88 81 72 132 142 40 544 36 60 39 35 0 0 0 0 0 0 0 0 0 27 2 0 0 25 COG1238(Predicted membrane protein) 184 133 128 159 7 12 45 55 33 30 16 46 4 44 50 33 57 55 41 58 44 73 83 49 53 42 71 65 66 3 41 95 105 59 214 237 57 86 62 93 35 28 0 0 0 0 0 0 0 0 0 27 1 1 0 49 COG0351(Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase) 323 159 110 157 10 27 54 25 16 16 23 26 7 22 22 45 55 31 23 52 71 33 99 56 71 53 35 60 59 15 59 82 101 57 168 202 42 188 59 63 26 28 0 2 4 0 3 0 0 0 1 35 0 0 0 41 COG0506(Proline dehydrogenase) 329 101 164 89 23 12 26 20 16 17 16 24 16 47 29 41 40 40 29 43 45 45 78 34 39 87 44 45 25 23 19 84 93 48 139 215 70 442 43 74 33 19 0 0 0 1 0 0 0 0 0 19 0 0 0 28 COG0146(N-methylhydantoinase B/acetone carboxylase, alpha subunit) 307 91 219 139 18 33 22 33 16 31 9 9 15 151 28 22 32 4 80 80 37 51 107 57 54 51 71 40 37 13 38 80 42 32 107 154 36 279 65 71 29 27 2 0 1 0 0 2 0 0 2 32 0 0 0 48 COG0306(Phosphate/sulphate permeases) 347 133 140 87 22 7 54 44 33 26 12 29 19 72 37 23 33 33 40 49 28 30 57 33 32 58 68 45 45 20 34 102 87 94 255 197 61 80 60 112 50 38 1 3 0 0 2 0 0 1 0 36 0 0 0 35 COG2128(Uncharacterized conserved protein) 532 122 181 118 7 18 40 22 25 4 20 23 20 79 36 40 43 27 44 40 47 52 100 44 47 70 54 53 48 11 54 84 58 45 122 183 42 130 31 67 19 31 0 0 0 0 2 0 0 0 0 14 0 0 1 41 COG1018(Flavodoxin reductases (ferredoxin-NADPH reductases) family 1) 934 44 53 48 18 10 14 45 35 17 44 21 14 85 41 35 31 29 34 14 9 11 45 20 25 74 45 23 23 8 10 52 54 37 118 122 50 418 54 55 10 14 0 0 2 0 4 0 0 0 0 22 1 0 0 19 COG0678(Peroxiredoxin) 157 100 101 125 4 20 38 76 19 16 23 31 20 39 34 31 49 34 30 59 49 43 84 48 50 68 71 79 66 30 38 133 119 98 215 183 56 112 76 83 43 28 0 0 0 2 0 0 0 1 0 32 1 0 0 76 COG5470(Uncharacterized conserved protein) 152 169 152 168 8 18 44 61 12 24 8 37 10 41 20 30 41 37 34 66 61 52 119 73 48 24 59 41 44 7 43 104 97 60 253 233 42 132 54 76 25 16 0 0 0 0 0 0 0 1 1 37 0 0 0 48 COG3346(Uncharacterized conserved protein) 136 99 98 125 6 12 42 44 23 17 17 37 19 53 33 53 73 75 44 53 38 39 65 52 57 81 47 69 52 5 54 116 99 85 246 141 57 261 57 65 31 27 0 0 0 0 1 0 0 0 0 28 0 1 0 48 COG3246(Uncharacterized conserved protein) 271 154 125 172 3 25 37 59 18 12 9 19 26 74 17 38 19 22 50 50 36 43 103 67 44 48 51 63 40 10 37 86 57 54 187 245 24 191 68 81 17 38 0 0 2 0 0 0 2 0 0 35 0 0 0 51 COG0238(Ribosomal protein S18) 130 118 162 146 9 10 36 36 32 12 17 18 24 37 42 38 55 67 40 44 67 51 92 57 55 128 61 39 48 13 51 88 72 64 195 186 64 234 50 64 26 32 0 0 1 0 0 1 0 0 1 23 1 0 0 40 COG4993(Glucose dehydrogenase) 248 137 360 191 9 3 17 43 21 28 17 40 32 180 44 55 56 31 68 63 59 51 111 62 67 43 40 42 19 10 12 62 51 38 65 179 57 113 42 27 26 12 0 0 0 0 0 0 0 0 0 8 0 2 0 35 COG1835(Predicted acyltransferases) 569 49 49 70 10 4 11 44 19 19 13 20 6 40 17 20 123 192 28 30 49 23 34 21 28 350 21 22 28 7 21 62 38 32 85 101 36 440 25 32 21 23 0 0 0 0 0 1 2 0 0 14 0 1 0 24 COG1145(Ferredoxin) 327 109 76 128 7 11 43 37 20 10 25 27 20 56 18 39 73 56 37 49 64 28 59 49 56 116 56 49 42 11 38 84 76 54 131 153 63 355 48 63 16 22 0 0 0 0 2 0 0 0 0 27 0 0 1 42 COG2941(Ubiquinone biosynthesis protein COQ7) 157 166 144 165 5 12 46 49 16 19 20 49 18 52 27 30 42 42 35 40 44 44 114 50 63 29 52 57 58 7 46 98 86 81 223 219 32 174 45 71 26 31 0 0 0 2 0 0 0 0 0 30 1 1 0 38 COG2332(Cytochrome c-type biogenesis protein CcmE) 150 202 138 165 6 20 44 55 19 18 20 27 15 43 44 46 42 33 27 66 75 36 77 65 42 38 52 61 52 9 53 92 102 56 219 219 33 149 49 53 27 24 0 0 0 0 0 0 2 0 0 27 0 1 1 56 COG3474(Cytochrome c2) 100 132 131 124 4 10 31 32 19 33 25 30 14 71 30 25 36 18 29 52 47 34 81 59 50 24 62 60 28 4 50 94 79 71 205 198 41 487 33 64 28 24 0 0 0 0 0 1 1 0 0 29 0 1 1 44 COG1975(Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family) 305 94 151 127 5 11 10 18 21 11 17 17 12 48 29 32 58 44 54 71 68 66 78 40 30 81 68 41 40 6 29 83 68 58 202 236 49 196 55 86 22 29 0 0 0 0 0 0 0 0 0 14 0 0 0 58 COG2008(Threonine aldolase) 164 72 102 92 13 22 27 56 31 26 16 17 22 76 42 42 65 61 47 64 35 60 91 64 35 156 69 47 46 20 22 81 69 82 152 183 43 253 49 72 34 28 0 0 0 0 1 0 0 2 2 24 0 0 0 60 COG0580(Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)) 285 208 216 197 21 10 64 22 20 20 7 17 20 34 31 34 60 45 36 47 61 78 99 53 44 138 39 36 51 7 25 59 39 42 168 98 25 181 45 55 22 20 0 2 0 0 1 0 0 0 0 17 1 0 0 34 COG0219(Predicted rRNA methylase (SpoU class)) 209 149 153 162 7 11 58 53 9 21 23 30 11 44 41 36 35 34 40 74 56 53 107 59 40 41 56 59 49 8 61 87 100 62 153 205 56 145 64 38 32 31 0 0 0 1 0 0 0 0 2 28 0 0 0 32 COG2130(Putative NADP-dependent oxidoreductases) 279 202 278 153 14 12 41 37 27 29 22 28 28 66 14 32 10 4 80 63 64 58 89 65 54 20 49 51 49 15 43 86 50 41 178 195 19 91 48 41 23 21 0 0 0 0 0 0 0 0 0 22 0 1 0 25 COG0545(FKBP-type peptidyl-prolyl cis-trans isomerases 1) 291 82 127 100 33 30 20 37 21 16 41 18 9 69 30 35 51 50 35 52 62 43 90 34 42 84 27 39 36 27 29 76 51 40 114 146 68 468 38 81 20 18 2 0 0 0 0 0 0 0 0 18 0 0 0 13 NOG25484() 12 51 217 47 130 9 44 53 33 21 43 10 9 37 25 13 11 58 32 64 65 77 88 20 31 19 53 39 34 7 33 97 130 87 292 235 22 147 37 148 90 47 0 0 0 0 0 0 0 0 0 22 0 0 0 60 COG1600(Uncharacterized Fe-S protein) 180 87 162 99 24 21 26 30 26 23 31 45 26 76 12 35 41 23 43 40 66 47 108 49 57 78 71 58 49 17 50 91 51 46 131 172 48 290 62 72 18 26 0 0 0 0 0 2 0 0 2 40 0 2 0 40 COG3175(Cytochrome oxidase assembly factor) 172 167 105 144 7 11 61 63 13 30 16 30 21 51 45 34 36 57 47 56 36 53 75 54 67 34 51 45 56 9 43 117 84 64 214 164 36 123 49 77 33 38 0 0 0 2 0 0 0 0 0 34 3 3 0 42 COG2358(TRAP-type uncharacterized transport system, periplasmic component) 218 136 94 150 2 19 23 34 15 25 22 27 18 40 34 31 61 79 49 49 46 34 68 56 48 42 54 36 26 2 25 74 79 50 151 226 48 382 33 48 20 21 0 0 0 0 0 0 0 0 0 34 0 0 0 38 COG4581(Superfamily II RNA helicase) 76 52 56 71 28 37 30 34 18 21 15 22 14 30 21 32 103 94 53 53 84 47 108 66 73 230 44 46 72 30 70 52 57 31 73 112 29 442 68 30 37 33 0 0 0 0 0 0 0 0 0 24 0 0 0 45 COG0344(Predicted membrane protein) 174 141 130 125 6 13 46 37 23 8 14 33 7 21 15 34 20 45 35 71 56 53 104 75 64 113 54 53 49 14 61 94 83 56 177 224 33 137 66 55 37 33 0 0 0 2 0 0 0 0 0 30 2 0 0 40 COG0421(Spermidine synthase) 334 131 87 146 9 14 26 35 21 12 19 46 12 41 35 39 34 24 40 49 34 40 91 57 47 22 27 53 48 10 65 82 79 43 130 183 50 344 47 36 22 17 0 1 0 0 0 0 0 0 0 32 0 0 0 47 COG0589(Universal stress protein UspA and related nucleotide-binding proteins) 712 54 68 58 12 10 17 25 15 21 18 8 15 50 21 7 35 35 23 18 14 15 41 24 24 117 42 17 32 13 22 44 26 23 80 82 60 730 53 31 7 10 0 0 0 0 0 0 0 0 0 10 0 0 2 20 COG1062(Zn-dependent alcohol dehydrogenases, class III) 189 90 130 111 15 22 19 51 10 25 21 7 27 86 21 24 23 32 52 81 26 41 53 48 47 119 43 21 31 14 25 88 75 70 166 188 39 382 58 73 22 31 0 0 0 0 0 0 0 0 0 17 0 0 0 47 COG3660(Predicted nucleoside-diphosphate-sugar epimerase) 118 179 163 170 5 10 60 82 20 37 16 30 12 15 32 36 31 45 26 51 58 49 84 55 67 28 52 76 40 7 45 99 90 79 212 238 48 86 38 42 37 14 2 0 0 0 0 0 0 0 0 29 2 0 0 40 COG0713(NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)) 146 109 119 126 3 10 47 50 10 21 16 32 18 57 31 55 59 59 31 39 59 73 119 79 51 162 49 51 59 8 43 78 106 58 117 191 45 116 54 44 39 23 0 0 0 0 2 0 2 0 0 23 0 0 0 64 COG0323(DNA mismatch repair enzyme (predicted ATPase)) 181 42 129 71 36 47 31 35 25 19 45 10 27 59 25 19 34 39 44 40 29 46 69 36 47 35 54 46 27 16 29 82 101 56 164 129 65 453 64 106 28 37 0 2 0 0 0 0 0 0 0 24 0 0 0 44 COG0029(Aspartate oxidase) 195 58 89 66 23 17 42 46 29 12 19 30 23 53 31 25 92 96 37 36 72 45 101 38 56 203 39 26 47 29 45 79 44 41 59 119 44 420 55 42 37 22 4 4 0 0 0 2 0 0 0 13 0 0 0 32 COG1802(Transcriptional regulators) 625 31 37 41 10 22 8 37 27 16 41 16 20 142 24 19 59 24 63 43 7 19 34 21 10 84 60 30 12 5 6 36 22 28 89 68 60 687 32 33 10 19 0 2 0 0 0 0 2 0 0 19 0 0 0 34 NOG06507(Major facilitator superfamily MFS_1 protein) 102 112 102 111 5 11 37 57 25 9 28 34 22 40 20 39 39 72 46 46 53 31 91 28 42 91 56 40 27 8 47 83 69 49 169 256 57 311 67 59 28 32 0 4 0 0 0 0 0 0 0 19 0 0 2 47 COG0063(Predicted sugar kinase) 184 129 241 172 9 11 32 39 10 13 10 8 12 41 35 17 38 20 28 38 59 70 112 49 60 109 21 43 54 34 47 54 35 18 89 161 67 393 42 34 20 31 0 0 0 0 1 0 0 0 0 21 0 0 0 11 COG0698(Ribose 5-phosphate isomerase RpiB) 80 99 101 126 14 8 47 58 21 18 5 34 12 26 17 32 66 47 32 74 46 44 91 37 67 143 48 43 61 8 35 102 93 91 185 223 55 179 49 72 26 27 0 0 1 0 0 1 0 1 0 26 0 0 1 41 COG1329(Transcriptional regulators, similar to M. xanthus CarD) 103 129 97 146 0 20 53 39 13 17 21 22 7 29 27 30 62 64 31 54 46 45 68 41 43 134 51 55 50 2 67 93 82 75 213 251 21 171 42 64 23 23 0 0 0 0 0 0 0 0 0 28 0 1 0 60 COG0291(Ribosomal protein L35) 147 147 140 174 17 9 44 43 20 22 20 20 13 33 31 24 55 41 34 43 57 42 100 54 65 46 50 63 50 14 40 93 90 56 167 179 28 226 52 60 18 27 0 1 0 0 0 0 0 2 0 19 0 0 0 36 COG1508(DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog) 283 109 155 91 28 20 33 31 21 28 26 29 17 52 21 22 42 14 51 45 40 51 79 45 47 47 37 29 27 8 35 109 74 31 181 155 47 332 36 77 21 22 0 0 0 0 0 0 0 0 0 28 0 0 0 23 COG0398(Uncharacterized conserved protein) 176 124 89 172 7 12 27 51 15 21 19 21 11 42 26 33 40 37 26 41 57 37 114 64 73 23 44 56 57 32 76 77 84 54 141 187 51 224 65 67 28 27 0 0 0 1 0 0 6 0 0 21 0 0 0 40 COG4631(Xanthine dehydrogenase, molybdopterin-binding subunit B) 244 127 128 165 7 17 6 19 9 16 5 17 11 27 21 9 16 11 41 59 33 29 74 48 53 16 56 38 35 12 27 91 65 77 252 383 87 92 60 72 19 33 2 0 0 0 0 0 0 2 0 18 0 0 0 62 COG2274(ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain) 375 54 76 54 21 13 18 16 18 15 17 7 18 47 24 14 38 28 24 31 33 29 60 33 40 43 24 17 45 34 35 95 34 25 117 64 67 808 77 40 10 11 0 0 1 0 0 0 0 0 0 16 0 0 0 25 COG1893(Ketopantoate reductase) 421 123 93 120 7 25 34 47 11 17 7 10 15 65 31 25 34 34 31 63 49 50 115 48 67 26 45 56 53 15 37 76 66 44 152 120 32 142 53 77 36 28 0 0 0 0 0 0 0 1 0 28 1 1 0 58 COG4311(Sarcosine oxidase delta subunit) 173 136 84 156 2 13 43 51 26 20 24 25 31 58 22 33 29 11 39 60 49 38 80 48 43 4 53 56 39 1 38 90 91 62 218 277 38 128 46 77 37 39 0 2 1 2 0 0 0 0 1 40 0 0 0 51 COG1559(Predicted periplasmic solute-binding protein) 158 96 141 61 18 9 33 30 17 13 18 16 22 49 41 17 64 57 47 40 38 54 84 44 50 112 55 61 38 9 23 68 61 40 148 156 66 412 46 60 29 28 2 0 0 0 0 0 0 0 0 19 0 0 0 34 COG0721(Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit) 122 126 104 134 8 10 46 54 18 33 11 30 16 48 13 35 63 79 37 37 55 40 74 51 41 99 48 36 40 16 44 93 74 60 147 198 46 274 49 57 30 32 0 1 0 0 0 1 0 1 0 20 0 0 0 30 COG4999(Uncharacterized domain of BarA-like signal transduction histidine kinases) 1564 81 30 12 3 9 6 15 0 2 34 3 9 36 8 11 21 23 19 2 7 9 17 11 10 23 13 1 9 8 9 9 2 2 8 23 164 432 7 10 1 2 0 0 0 0 0 2 0 0 0 4 0 0 0 3 COG0182(Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family) 142 157 125 174 5 10 29 29 2 17 4 30 14 32 16 35 34 34 32 58 52 48 74 64 46 52 42 54 36 3 46 90 111 48 185 233 34 220 66 70 31 19 0 0 0 0 0 0 0 0 0 27 0 0 0 41 COG1643(HrpA-like helicases) 455 52 117 44 27 49 13 27 15 23 36 8 27 71 30 33 78 35 88 26 10 12 34 37 26 86 35 24 14 71 12 38 26 23 67 77 92 548 80 34 14 22 0 0 0 0 0 0 1 0 0 10 0 0 0 19 COG1066(Predicted ATP-dependent serine protease) 184 39 86 54 22 15 27 30 16 21 37 16 26 72 15 27 94 107 48 20 35 42 89 39 49 189 50 28 34 19 38 87 50 34 100 110 54 461 48 65 18 28 0 2 0 0 0 0 0 0 0 16 0 0 2 15 NOG08353() 99 132 90 154 20 9 40 61 21 22 25 41 8 31 32 23 35 35 27 43 66 41 103 58 61 26 52 41 39 11 43 85 110 90 266 180 31 94 50 84 43 34 0 0 0 0 0 0 0 0 0 26 0 0 0 73 COG1953(Cytosine/uracil/thiamine/allantoin permeases) 350 146 101 148 1 3 32 53 23 10 19 31 16 11 49 45 59 34 18 57 43 25 73 41 34 0 25 54 38 1 36 98 89 60 197 329 40 0 55 53 31 46 0 0 0 0 0 0 0 0 0 30 1 0 0 44 NOG11366() 127 165 114 145 2 6 50 67 17 27 7 33 8 16 20 30 26 37 29 76 50 51 97 58 62 0 54 58 67 1 55 83 106 58 213 235 39 87 51 62 36 44 0 0 0 0 0 2 1 3 0 23 1 0 0 49 COG1268(Uncharacterized conserved protein) 103 130 94 112 4 11 50 52 16 17 17 23 24 24 41 32 38 54 28 57 58 43 104 56 70 35 31 51 46 19 48 75 78 69 172 216 28 270 39 62 45 23 4 0 2 0 0 1 0 0 2 31 0 1 0 35 COG3004(Na+/H+ antiporter) 176 93 80 127 3 4 36 38 10 34 15 35 10 64 24 26 61 73 38 53 69 40 81 55 40 99 38 38 45 2 42 93 79 51 154 205 59 175 52 76 21 32 0 0 2 0 0 1 0 0 0 16 0 0 0 60 COG1495(Disulfide bond formation protein DsbB) 175 110 129 128 2 11 47 38 11 27 21 29 13 44 11 29 47 48 35 41 46 42 84 48 47 43 67 64 55 7 42 101 80 66 190 195 40 164 47 66 23 29 0 0 0 1 0 0 0 0 0 25 0 2 0 54 COG4122(Predicted O-methyltransferase) 283 127 126 124 18 10 57 47 23 13 23 26 5 19 18 17 57 58 25 46 41 32 86 55 36 111 44 51 36 4 38 65 83 50 174 205 54 136 38 37 40 26 0 0 0 0 0 0 0 0 0 25 0 0 0 34 COG0268(Ribosomal protein S20) 142 121 148 115 7 12 26 49 23 13 13 22 17 29 30 14 49 50 27 47 62 54 89 50 53 90 54 51 42 14 51 72 75 47 167 186 41 259 54 59 23 17 0 4 0 0 0 1 0 0 0 13 0 0 0 38 COG2120(Uncharacterized proteins, LmbE homologs) 54 57 121 52 8 10 31 28 23 18 23 29 23 43 28 21 81 99 31 32 38 36 68 37 53 276 42 53 32 7 17 52 63 47 104 191 55 436 38 56 20 19 0 0 1 0 0 0 0 0 0 30 0 1 0 34 COG1139(Uncharacterized conserved protein containing a ferredoxin-like domain) 457 51 44 53 7 6 23 34 5 24 14 24 9 40 30 42 47 44 28 53 19 20 33 35 28 68 79 39 18 2 21 37 41 27 94 110 58 714 26 34 14 2 2 0 0 0 0 0 0 0 0 1 0 0 0 56 COG0781(Transcription termination factor) 136 93 149 108 17 14 30 52 23 20 10 28 18 33 15 23 59 66 39 31 57 30 74 27 55 111 41 43 35 12 40 77 67 37 144 159 64 333 58 62 22 33 0 1 1 0 0 0 2 1 0 20 0 0 0 29 COG3176(Putative hemolysin) 188 111 89 99 27 30 85 24 22 18 12 12 27 45 15 17 17 68 23 46 40 36 83 43 57 56 45 27 37 5 29 74 64 56 126 92 28 451 77 66 28 29 0 0 1 0 0 0 0 0 0 31 0 0 0 42 COG2304(Uncharacterized protein containing a von Willebrand factor type A (vWA) domain) 337 65 159 67 35 12 37 39 37 19 34 17 27 50 40 27 29 21 41 28 35 44 68 27 50 64 24 27 41 21 21 57 65 36 102 142 89 365 30 76 26 32 0 0 0 0 0 0 0 3 0 7 0 3 0 22 COG3651(Uncharacterized protein conserved in bacteria) 96 124 130 138 15 5 55 36 19 20 17 25 13 28 24 35 36 42 32 63 71 59 83 41 62 68 41 36 48 18 52 109 81 57 156 171 21 215 55 61 31 28 0 0 1 2 2 0 0 0 0 20 0 0 0 55 COG1899(Deoxyhypusine synthase) 105 141 117 176 2 4 36 39 15 2 15 21 7 6 42 25 37 40 23 63 40 97 116 64 70 82 46 34 44 20 43 87 78 73 159 245 71 26 44 52 41 39 0 0 0 0 0 1 0 0 0 39 0 0 0 69 COG3088(Uncharacterized protein involved in biosynthesis of c-type cytochromes) 184 177 136 164 7 21 40 49 18 10 17 25 21 24 18 39 24 26 21 44 48 41 88 46 62 27 37 58 46 7 31 81 71 60 197 215 40 150 51 51 30 25 0 1 0 1 0 0 0 2 0 25 0 0 0 39 COG2917(Intracellular septation protein A) 164 112 82 125 6 16 48 57 15 22 23 18 16 32 26 35 31 27 24 46 53 44 89 51 52 29 34 59 35 4 48 73 92 55 251 247 55 166 48 59 32 22 0 2 1 0 0 0 0 0 0 32 0 0 0 36 COG3104(Dipeptide/tripeptide permease) 441 103 138 90 40 16 58 23 25 27 18 21 20 42 26 26 12 28 39 45 39 26 71 30 46 47 42 50 37 18 24 92 61 42 194 152 11 145 57 90 24 16 0 0 0 1 0 0 0 0 0 24 1 0 0 16 COG0456(Acetyltransferases) 181 83 131 91 7 20 28 13 12 21 8 12 7 65 31 26 70 79 36 47 53 39 80 30 37 212 37 40 28 22 40 77 48 37 110 136 48 382 54 35 23 12 0 0 0 0 1 0 0 0 0 15 0 2 0 26 COG3496(Uncharacterized conserved protein) 208 124 111 144 4 15 26 43 17 18 19 23 15 43 30 19 46 32 34 32 49 45 94 44 49 48 59 55 52 6 42 91 77 65 204 179 36 156 37 51 31 46 0 0 0 0 0 0 0 0 2 27 0 0 0 43 COG0639(Diadenosine tetraphosphatase and related serine/threonine protein phosphatases) 425 85 124 85 21 25 29 26 28 20 22 28 16 62 26 17 40 33 33 26 32 27 60 35 37 48 42 27 29 55 22 48 39 44 94 99 71 444 41 47 17 16 0 0 0 0 0 0 0 0 0 11 1 0 1 24 COG3800(Predicted transcriptional regulator) 102 108 77 119 7 19 46 78 31 25 39 45 10 39 41 28 15 54 21 58 35 42 52 47 55 45 47 42 51 0 27 88 66 47 153 247 34 328 33 57 30 24 0 0 0 0 0 0 0 0 0 21 1 0 0 44 COG1525(Micrococcal nuclease (thermonuclease) homologs) 156 131 91 137 10 10 42 43 11 18 14 28 9 28 18 23 49 51 27 40 47 38 73 50 39 105 38 36 45 15 32 65 81 39 169 173 48 319 40 61 25 40 0 0 0 0 1 0 2 3 0 15 0 0 0 40 COG0278(Glutaredoxin-related protein) 139 150 170 149 9 12 52 48 19 18 15 24 8 37 19 33 30 21 28 45 55 50 71 55 83 22 52 51 45 25 43 94 71 50 171 181 44 178 48 52 30 18 0 1 0 0 0 1 0 0 0 24 0 0 0 32 COG4977(Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain) 1564 39 16 9 8 7 6 21 18 15 23 3 19 60 13 16 15 12 30 15 9 4 22 9 5 9 34 14 11 5 10 54 39 28 75 47 41 160 21 27 9 8 1 0 0 0 0 0 0 0 0 5 0 0 0 14 COG2849(Uncharacterized protein conserved in bacteria) 366 110 390 84 12 22 15 26 32 11 16 18 15 40 53 28 13 25 41 37 32 66 112 36 56 27 54 70 41 12 34 67 40 19 56 177 39 83 13 72 25 26 0 2 0 0 0 0 0 0 2 20 0 0 0 30 COG0296(1,4-alpha-glucan branching enzyme) 701 31 70 47 15 18 4 12 8 13 3 4 2 33 7 12 57 80 28 11 37 40 72 44 55 165 27 40 28 45 41 48 26 12 43 33 18 509 48 29 8 6 0 1 0 0 0 0 0 0 0 5 0 0 0 18 COG3344(Retron-type reverse transcriptase) 322 122 45 96 15 10 27 23 8 17 23 28 16 27 23 20 48 35 16 52 24 28 54 42 29 29 39 24 29 13 23 47 56 31 109 76 123 632 51 26 21 24 0 0 2 0 0 2 0 0 0 9 2 0 0 34 COG2308(Uncharacterized conserved protein) 381 159 108 198 24 43 86 21 1 3 0 1 6 16 15 4 36 30 16 23 63 72 127 88 84 24 17 32 77 20 60 2 2 10 33 7 22 579 31 6 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 20 COG1335(Amidases related to nicotinamidase) 739 61 100 82 15 23 11 10 20 15 12 7 10 47 26 6 33 47 32 32 38 33 68 38 44 66 23 22 36 16 27 53 38 31 77 85 30 370 25 44 10 16 0 0 0 0 0 0 2 0 0 9 1 0 0 18 COG0220(Predicted S-adenosylmethionine-dependent methyltransferase) 150 115 153 86 24 22 22 30 23 12 29 30 14 54 19 14 50 45 35 50 43 48 79 43 45 107 40 47 40 28 47 76 65 59 151 117 35 289 59 49 26 26 0 0 0 0 0 0 0 0 0 20 0 0 0 26 COG4172(ABC-type uncharacterized transport system, duplicated ATPase component) 288 137 133 96 6 19 40 49 5 20 10 14 15 57 26 13 20 8 38 42 51 36 69 43 44 31 52 40 29 17 30 95 55 61 194 180 55 190 62 68 18 31 0 1 0 0 0 0 0 1 0 20 0 0 0 30 COG2884(Predicted ATPase involved in cell division) 138 65 117 58 9 5 35 34 30 12 32 15 25 52 24 36 56 77 30 33 30 43 64 35 32 146 56 63 25 6 29 58 68 44 143 126 62 359 36 69 42 38 2 0 0 0 2 0 1 0 0 18 0 0 0 58 COG4146(Predicted symporter) 66 134 191 77 38 9 35 55 19 34 39 19 11 44 30 55 20 19 41 59 41 50 104 40 62 12 44 46 41 12 20 119 75 67 225 138 54 166 42 68 38 30 0 1 0 0 0 2 1 0 2 10 0 0 0 30 COG2814(Arabinose efflux permease) 1642 33 57 33 2 0 0 3 4 3 2 1 3 28 3 10 32 48 22 14 13 7 23 13 15 144 16 6 7 5 8 8 6 0 10 21 7 268 2 6 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG1133(ABC-type long-chain fatty acid transport system, fused permease and ATPase components) 107 136 79 134 9 11 63 52 14 11 13 30 29 65 38 27 38 18 21 45 41 50 72 66 52 25 60 50 46 4 47 109 86 67 189 248 36 2 68 108 19 36 1 0 0 1 1 7 0 0 0 34 0 0 0 62 COG0736(Phosphopantetheinyl transferase (holo-ACP synthase)) 168 135 121 117 6 7 41 44 11 21 6 28 11 27 26 33 38 39 21 46 46 50 86 59 52 56 45 53 40 6 31 76 80 62 167 201 40 201 61 52 23 28 0 0 0 0 0 0 1 0 0 21 0 0 0 41 COG2823(Predicted periplasmic or secreted lipoprotein) 436 125 81 122 1 7 36 50 12 22 23 31 21 26 37 25 35 46 28 35 50 41 57 43 39 31 44 41 35 3 45 62 65 45 153 182 35 164 37 45 19 22 0 0 0 0 0 0 0 2 0 17 0 0 0 36 COG2364(Predicted membrane protein) 93 97 102 116 5 7 35 44 20 29 8 23 15 45 31 25 51 65 40 51 38 49 64 47 62 75 47 42 46 1 24 89 87 72 198 230 32 129 50 72 39 35 0 0 2 0 0 1 0 1 0 27 0 0 2 45 COG4624(Iron only hydrogenase large subunit, C-terminal domain) 72 91 94 108 3 8 27 34 15 10 9 21 14 31 12 27 42 43 35 65 38 25 61 32 43 38 31 26 33 5 25 76 66 33 136 201 49 636 42 60 22 19 0 0 0 2 2 0 0 0 0 15 0 0 0 28 COG0514(Superfamily II DNA helicase) 489 46 45 41 32 14 19 32 52 19 39 18 12 65 27 29 33 37 39 31 24 22 36 14 39 35 33 32 16 15 8 85 65 41 129 139 77 333 62 83 20 22 0 0 0 0 0 1 0 0 0 22 2 0 2 27 COG0175(3-phosphoadenosine 5-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes) 343 66 44 59 26 22 35 28 17 19 36 10 23 81 23 16 51 78 36 26 25 37 43 25 22 129 23 26 39 29 25 56 52 41 82 79 70 503 41 36 10 11 0 0 0 0 2 0 2 0 0 23 0 0 0 31 COG1191(DNA-directed RNA polymerase specialized sigma subunit) 497 120 109 84 11 22 29 31 16 31 22 21 22 43 25 13 33 35 25 21 35 19 59 40 40 50 54 23 25 7 20 77 42 38 107 115 35 333 51 31 20 17 0 0 0 0 0 0 0 0 0 18 0 0 0 34 COG1042(Acyl-CoA synthetase (NDP forming)) 253 72 150 90 10 20 14 24 10 14 20 18 25 77 39 12 30 39 37 35 25 32 52 34 27 128 21 35 41 13 11 41 52 31 103 169 49 473 32 62 14 20 0 0 0 2 0 0 0 0 0 20 0 0 0 23 COG2135(Uncharacterized conserved protein) 115 79 99 107 9 18 32 35 14 7 11 11 7 32 32 26 62 59 29 47 51 60 80 49 58 119 43 62 44 24 44 88 80 56 154 110 18 278 59 42 38 32 0 0 0 0 0 0 0 0 0 28 1 0 0 49 COG0191(Fructose/tagatose bisphosphate aldolase) 228 65 63 61 14 21 37 16 10 32 26 25 14 57 10 18 84 63 32 34 41 33 74 49 53 29 30 39 36 26 44 51 40 40 134 138 68 480 45 51 25 24 0 0 0 0 0 0 1 0 0 17 0 0 0 20 NOG06868(Photosystem protein) 51 23 44 65 19 6 21 80 14 19 3 6 55 0 2 2 2 5 13 32 103 74 245 119 121 102 58 82 140 188 68 49 25 31 44 69 0 123 113 47 38 49 2 0 1 0 0 0 0 1 0 52 0 0 2 89 COG0241(Histidinol phosphatase and related phosphatases) 239 90 124 85 13 13 48 57 22 19 20 24 14 56 28 27 44 49 31 29 46 47 71 43 67 104 41 51 45 17 43 63 68 48 112 203 42 155 27 61 25 21 0 0 0 0 0 0 0 0 0 20 0 0 0 35 COG2992(Uncharacterized FlgJ-related protein) 130 119 89 143 3 12 38 84 16 29 24 21 14 33 46 44 47 51 27 51 41 39 79 54 66 21 41 52 51 3 59 75 94 60 189 233 37 10 57 66 23 22 2 0 0 0 0 0 0 0 4 35 0 0 0 50 COG0271(Stress-induced morphogen (activity unknown)) 141 142 132 138 8 10 60 37 17 14 20 21 17 35 10 31 37 13 29 38 62 53 79 46 78 34 62 38 54 18 43 80 68 45 147 165 35 195 49 49 39 27 0 0 0 0 0 0 0 0 0 27 1 0 0 36 COG0620(Methionine synthase II (cobalamin-independent)) 284 123 157 133 10 20 30 18 13 11 6 11 12 42 11 21 59 71 32 46 36 25 65 72 33 122 38 22 38 1 48 90 56 43 180 178 29 52 49 49 14 33 0 0 4 0 0 0 0 0 0 33 0 0 0 54 COG3752(Predicted membrane protein) 120 132 229 108 7 22 42 38 25 18 18 38 20 35 53 37 36 17 40 49 64 58 92 42 44 65 56 44 33 21 39 83 52 40 169 160 27 85 47 61 27 25 0 0 0 0 0 0 0 0 0 22 1 0 0 31 COG2928(Uncharacterized conserved protein) 144 90 122 134 4 10 41 32 20 21 24 22 15 33 23 35 39 50 26 39 56 47 102 48 63 34 54 47 67 10 62 88 76 36 202 176 42 109 68 48 26 22 0 1 0 0 0 0 0 1 0 17 0 1 0 41 COG2188(Transcriptional regulators) 1063 33 33 43 14 12 39 13 20 13 16 12 13 49 28 19 51 58 28 20 19 23 34 17 10 76 25 10 9 8 13 34 44 28 44 63 41 271 26 38 12 11 0 0 0 0 0 0 0 0 0 7 0 0 0 27 COG0696(Phosphoglyceromutase) 110 45 51 82 15 18 25 38 27 11 26 25 28 46 27 28 38 30 34 39 67 62 94 58 67 55 28 34 30 17 54 99 50 33 134 142 99 344 73 65 27 24 0 0 1 0 0 0 1 0 0 27 0 1 0 28 COG0704(Phosphate uptake regulator) 214 187 162 209 3 14 53 17 15 11 21 1 4 43 26 23 60 64 29 64 62 65 114 61 64 194 32 23 14 1 13 27 21 17 21 32 50 322 5 12 15 4 0 0 0 0 1 0 0 0 0 4 0 0 0 52 COG3666(Transposase and inactivated derivatives) 334 105 74 64 11 8 27 39 17 14 26 15 9 27 18 21 40 32 31 24 29 44 60 30 38 60 39 38 34 9 24 50 31 41 87 112 75 551 42 48 17 19 0 0 0 0 0 0 0 0 0 14 0 0 0 18 COG1319(Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs) 161 85 154 98 9 17 9 41 7 19 6 8 14 79 39 26 50 39 48 74 54 50 94 50 59 104 62 54 32 12 28 63 57 52 92 174 34 198 38 62 16 19 1 0 0 0 0 0 0 0 0 7 0 0 0 47 COG2265(SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase) 244 53 121 55 25 27 24 31 20 21 31 17 29 69 26 21 60 64 53 26 34 20 40 19 27 187 22 24 23 18 14 45 33 27 93 101 63 514 34 36 11 7 0 0 0 0 0 0 0 0 0 14 0 0 0 17 COG0640(Predicted transcriptional regulators) 593 37 52 42 5 9 7 23 8 21 22 11 16 71 12 13 40 25 31 20 21 15 46 25 13 60 32 17 9 4 22 36 15 9 54 56 68 770 29 23 9 11 0 0 0 0 0 0 0 0 0 11 2 0 0 22 COG2854(ABC-type transport system involved in resistance to organic solvents, auxiliary component) 223 151 128 132 9 4 29 44 21 25 19 27 22 45 21 37 28 41 26 58 48 36 84 51 41 29 48 42 29 4 31 84 66 55 156 188 46 113 48 57 22 8 0 0 0 0 1 0 1 1 0 20 0 0 0 38 COG4764(Uncharacterized protein conserved in bacteria) 121 153 128 160 6 10 42 40 18 24 12 27 15 15 22 22 31 29 25 57 43 35 61 55 33 20 55 40 37 5 51 90 82 43 220 172 58 127 60 63 24 22 0 2 0 0 0 0 0 1 0 31 0 0 0 48 COG2518(Protein-L-isoaspartate carboxylmethyltransferase) 193 116 104 81 15 17 43 50 17 18 25 12 14 61 31 21 29 29 34 34 32 45 75 38 58 50 46 47 28 9 23 75 66 44 145 152 74 245 30 92 41 21 0 1 0 0 0 2 0 0 0 18 0 0 0 30 COG0300(Short-chain dehydrogenases of various substrate specificities) 291 101 155 89 11 10 32 20 14 15 14 17 17 47 17 25 45 57 38 52 67 37 73 40 46 168 41 28 30 24 27 61 50 42 138 93 21 224 35 39 14 26 2 0 0 0 0 0 0 0 0 17 0 0 0 19 COG3320(Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes) 1461 24 32 28 10 4 4 8 6 8 10 8 9 28 6 9 29 16 31 12 30 24 26 31 34 32 14 10 14 17 18 23 16 18 21 50 22 221 14 22 5 15 0 0 0 0 0 0 0 0 0 4 0 0 0 3 COG1450(Type II secretory pathway, component PulD) 522 149 183 91 11 12 31 30 12 14 19 6 13 30 15 14 26 24 35 36 42 35 71 42 29 32 38 43 24 23 34 62 56 29 81 70 67 269 18 30 17 16 0 0 0 0 0 0 0 0 0 13 0 0 0 13 COG3883(Uncharacterized protein conserved in bacteria) 117 59 74 71 13 5 25 14 13 17 11 14 8 32 19 21 37 34 43 49 28 37 78 33 49 131 39 40 29 8 35 87 63 52 135 144 52 468 53 60 36 31 0 0 0 0 0 0 0 0 0 13 0 0 0 49 COG4160(ABC-type arginine/histidine transport system, permease component) 536 97 86 103 1 7 26 37 16 18 12 17 14 24 15 32 16 10 25 34 37 22 54 52 50 40 40 31 21 4 37 69 52 39 182 204 35 123 51 41 31 18 0 0 0 0 0 0 0 0 0 21 0 0 0 41 COG4149(ABC-type molybdate transport system, permease component) 519 59 51 48 3 9 19 33 12 10 8 20 13 55 9 13 15 47 19 32 26 27 49 15 17 47 29 17 23 4 11 46 39 32 78 101 83 678 20 25 13 7 0 0 0 0 0 0 0 0 0 12 0 0 0 25 COG0529(Adenylylsulfate kinase and related kinases) 269 58 79 79 13 16 18 20 13 16 25 15 10 76 22 20 39 41 34 46 48 31 58 45 53 165 32 24 33 23 31 64 48 30 96 112 53 374 70 43 14 14 0 0 0 1 0 0 0 0 0 20 0 0 0 25 COG1060(Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes) 129 85 173 93 1 5 14 11 16 14 4 15 24 45 49 29 25 50 36 46 48 29 107 43 39 152 76 58 42 11 31 80 83 40 66 169 42 161 35 71 37 36 0 0 0 0 0 0 0 0 0 11 0 0 2 72 COG1832(Predicted CoA-binding protein) 85 122 108 132 3 10 34 41 17 24 9 19 11 38 40 41 41 33 30 67 52 43 71 52 58 54 52 59 50 9 47 56 63 45 176 204 28 111 61 52 40 27 0 0 2 0 0 0 0 0 0 34 0 0 0 51 COG5405(ATP-dependent protease HslVU (ClpYQ), peptidase subunit) 162 110 105 121 3 16 47 35 14 13 14 17 19 21 30 29 37 36 20 69 57 33 87 54 49 7 44 39 40 9 30 57 65 56 178 220 44 178 45 72 20 35 1 0 1 0 0 0 0 0 0 20 1 0 0 40 COG4536(Putative Mg2+ and Co2+ transporter CorB) 166 110 152 107 11 28 35 59 26 22 27 28 20 49 26 28 29 14 34 47 35 23 83 46 45 11 43 42 32 11 27 86 72 36 135 149 42 275 48 50 21 19 0 0 0 0 0 0 0 2 0 18 0 0 0 31 COG1540(Uncharacterized proteins, homologs of lactam utilization protein B) 171 140 114 117 6 8 38 27 25 14 8 43 18 18 35 27 50 43 27 58 44 41 71 57 29 58 35 49 49 2 24 60 71 55 148 239 50 102 55 60 32 24 0 0 0 0 0 0 0 0 0 19 0 0 0 32 NOG11078(Clumping factor) 234 28 60 11 0 1 5 10 20 4 21 26 23 60 40 13 1 16 23 45 56 65 119 71 54 8 87 69 36 36 26 122 167 74 39 110 31 43 49 137 104 79 0 1 0 1 0 0 0 0 4 33 0 0 0 126 COG2049(Allophanate hydrolase subunit 1) 260 130 107 131 4 15 35 36 22 5 13 33 10 30 28 27 38 29 25 41 35 42 71 50 28 38 34 43 50 8 33 64 56 42 157 236 55 125 43 50 26 35 0 0 1 0 0 0 0 0 0 15 1 1 0 29 COG0803(ABC-type metal ion transport system, periplasmic component/surface adhesin) 161 31 72 71 9 23 14 26 12 6 9 11 11 48 11 17 12 41 24 43 94 66 108 63 97 87 24 33 54 35 53 87 59 37 60 60 35 405 58 43 38 23 0 0 0 0 0 0 0 2 2 33 1 0 1 76 COG1489(DNA-binding protein, stimulates sugar fermentation) 122 108 99 134 8 15 39 53 16 11 13 18 14 31 30 22 39 41 30 48 57 55 74 52 78 24 43 44 62 8 63 83 58 65 153 167 25 174 55 56 17 20 0 0 0 0 0 1 2 0 2 20 0 3 2 29 COG1806(Uncharacterized protein conserved in bacteria) 203 117 85 146 2 10 27 31 10 15 7 25 2 37 26 20 51 52 28 43 36 39 71 56 30 57 31 54 48 0 29 72 73 47 200 224 47 138 33 38 25 31 0 0 0 2 0 2 0 0 0 18 0 0 3 41 COG3794(Plastocyanin) 133 140 125 103 5 11 34 31 18 17 6 16 16 29 23 39 7 2 15 45 48 34 117 41 51 89 56 47 51 50 51 88 78 72 115 153 27 56 83 66 34 27 2 1 0 0 0 0 0 0 0 26 0 0 2 98 COG4772(Outer membrane receptor for Fe3+-dicitrate) 872 75 134 58 15 7 26 33 22 17 9 9 37 24 26 17 9 13 31 24 20 19 47 25 25 12 24 34 16 7 17 76 51 28 104 161 34 64 15 78 23 10 0 0 0 0 0 0 0 1 0 9 0 0 0 20 COG0474(Cation transport ATPase) 525 32 69 34 22 39 1 10 2 13 0 7 6 9 2 2 36 28 30 11 15 15 26 8 18 91 34 14 10 68 16 15 13 9 20 25 88 926 9 25 14 11 0 0 0 0 0 0 0 0 0 2 0 0 0 25 COG1862(Preprotein translocase subunit YajC) 151 139 111 116 13 8 30 30 16 36 26 30 18 38 26 27 31 28 29 36 40 47 66 44 36 51 55 44 30 8 39 71 52 56 175 176 61 168 47 45 26 18 0 1 1 0 0 1 0 0 2 29 0 0 0 43 COG2945(Predicted hydrolase of the alpha/beta superfamily) 120 123 96 116 3 6 28 40 14 21 18 21 11 22 33 20 61 56 29 45 47 35 59 47 40 78 36 47 33 3 43 66 88 50 147 166 21 279 41 45 21 23 1 2 0 0 1 0 0 0 0 30 0 1 0 35 COG4215(ABC-type arginine transport system, permease component) 392 113 92 97 2 5 34 37 13 14 13 18 12 27 7 38 19 13 29 48 33 35 58 54 36 4 32 41 25 6 29 71 52 29 188 193 33 215 54 28 26 33 0 0 0 0 0 0 0 0 0 22 0 0 0 42 COG1055(Na+/H+ antiporter NhaD and related arsenite permeases) 284 91 212 78 11 11 28 16 11 6 9 14 24 35 27 22 5 9 19 46 25 44 76 41 41 41 30 25 33 6 31 57 40 38 100 169 41 357 40 58 26 18 0 0 0 0 2 0 0 0 0 18 0 0 0 32 COG0437(Fe-S-cluster-containing hydrogenase components 1) 453 64 86 82 19 11 25 38 26 12 12 22 15 47 17 22 17 25 28 30 29 48 74 35 22 59 32 23 16 8 17 65 60 44 143 94 30 306 30 61 23 16 1 0 0 0 4 0 0 0 0 29 0 0 0 20 COG2947(Uncharacterized conserved protein) 167 121 93 130 11 7 26 32 8 24 12 25 10 35 26 19 32 39 22 49 48 37 64 45 55 62 45 37 44 12 59 76 68 42 147 205 44 133 43 44 27 28 0 0 1 1 0 1 0 2 1 26 1 1 0 42 COG3473(Maleate cis-trans isomerase) 157 145 111 140 3 8 20 54 25 10 21 35 17 55 39 18 27 6 39 60 29 33 47 43 35 9 32 29 37 6 38 74 58 54 165 226 41 152 55 52 21 36 0 0 0 0 0 0 0 2 0 23 0 0 0 36 COG2391(Predicted transporter component) 162 27 68 36 1 7 5 54 17 31 30 13 3 69 21 32 84 111 76 48 13 13 26 13 25 49 55 21 7 1 9 25 25 23 57 144 68 711 20 24 22 4 1 0 0 0 0 0 0 0 0 2 0 0 0 69 COG1331(Highly conserved protein containing a thioredoxin domain) 79 105 166 155 11 10 34 28 21 9 15 13 10 24 23 16 12 53 26 19 39 38 82 46 39 90 56 52 29 6 40 56 57 40 136 160 33 336 24 42 23 17 0 0 0 1 0 0 0 0 0 17 0 0 0 18 COG2111(Multisubunit Na+/H+ antiporter, MnhB subunit) 72 72 105 73 7 12 42 32 12 18 31 23 8 80 22 41 32 30 31 39 41 27 51 32 28 53 40 30 27 0 35 46 37 27 120 110 87 592 36 35 14 25 0 0 0 0 0 0 1 0 0 8 0 0 0 21 COG2962(Predicted permeases) 183 104 71 104 4 10 21 39 12 10 13 32 10 53 20 39 46 68 43 42 36 37 50 35 27 129 44 26 26 0 47 75 68 62 140 182 39 174 24 53 24 21 0 0 0 0 0 2 0 0 0 14 0 0 0 43 COG4585(Signal transduction histidine kinase) 1002 53 37 29 2 5 5 15 2 8 4 10 9 36 15 10 53 24 26 4 5 8 14 10 4 57 14 3 6 3 7 12 18 6 17 28 37 673 4 8 5 2 0 0 0 0 1 0 0 0 0 2 0 0 0 7 COG1748(Saccharopine dehydrogenase and related proteins) 94 78 93 67 14 17 27 30 16 20 18 13 9 53 27 20 40 83 34 31 32 37 76 36 29 152 42 32 34 17 25 104 96 56 169 172 40 105 38 82 34 39 0 0 0 1 0 0 0 0 0 22 2 0 0 43 COG1524(Uncharacterized proteins of the AP superfamily) 194 75 141 76 16 5 33 6 12 0 1 11 13 29 12 21 54 57 47 54 41 39 69 31 37 168 56 35 39 8 21 81 47 57 82 184 26 190 38 52 28 32 0 0 0 0 0 0 0 0 0 22 0 1 0 55 COG1435(Thymidine kinase) 99 77 136 85 15 12 28 39 30 27 13 20 40 45 26 27 52 70 43 68 35 36 91 44 31 126 53 28 29 7 19 68 55 64 113 155 25 160 41 63 23 19 0 0 0 0 0 0 0 1 0 15 0 0 0 41 COG1692(Uncharacterized protein conserved in bacteria) 79 151 82 144 7 8 50 37 11 27 8 26 21 23 17 31 36 36 21 38 57 51 69 43 72 35 47 39 42 4 38 63 106 64 178 192 35 98 57 48 23 22 1 0 0 1 0 0 1 0 0 17 0 0 0 37 COG3618(Predicted metal-dependent hydrolase of the TIM-barrel fold) 453 72 100 87 10 26 31 31 20 8 11 16 19 77 20 27 47 25 51 40 42 45 74 38 56 50 33 36 34 9 22 51 50 47 93 102 70 96 39 64 13 12 0 0 0 0 0 0 3 0 0 18 0 0 2 21 COG2855(Predicted membrane protein) 168 95 117 81 3 7 37 60 28 13 15 26 31 29 29 23 57 84 20 45 24 39 80 27 32 46 25 45 19 7 37 84 71 63 160 166 35 88 71 65 27 43 0 4 0 0 0 0 0 0 0 33 0 0 0 30 COG3250(Beta-galactosidase/beta-glucuronidase) 202 58 174 49 75 31 32 32 20 16 16 12 15 36 26 22 75 101 36 32 26 37 62 17 24 280 50 31 32 26 18 67 54 38 104 124 26 68 53 44 9 8 0 0 0 0 0 0 0 0 0 13 0 0 0 15 COG0671(Membrane-associated phospholipid phosphatase) 832 43 42 37 9 8 16 39 16 15 7 9 5 23 4 7 52 44 13 22 11 19 35 16 30 132 18 22 8 5 15 40 28 26 69 43 36 370 25 27 20 14 0 1 0 0 0 0 0 0 0 16 0 0 2 14 COG0279(Phosphoheptose isomerase) 133 89 107 97 5 12 41 21 13 16 14 23 19 35 31 21 57 46 16 26 50 48 83 48 60 107 41 42 26 18 32 64 62 53 94 168 64 225 39 37 21 23 2 0 0 0 0 0 0 0 0 17 0 0 0 38 COG0315(Molybdenum cofactor biosynthesis enzyme) 219 94 87 72 2 9 14 33 24 20 15 21 5 27 36 27 44 49 39 31 25 28 66 36 25 85 32 33 18 14 16 68 61 30 128 209 38 298 35 58 32 16 0 0 0 2 0 0 0 0 0 16 0 0 0 46 COG4181(Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component) 180 68 96 91 8 18 27 42 24 16 27 19 22 42 33 21 37 45 34 36 24 44 55 32 54 42 37 38 40 1 26 68 59 49 135 104 47 341 40 57 18 23 0 0 0 0 0 0 0 0 0 20 0 0 0 41 COG1586(S-adenosylmethionine decarboxylase) 114 103 63 101 4 10 29 44 10 9 8 20 9 10 19 15 10 22 25 59 50 53 111 67 63 78 38 50 80 54 83 71 55 37 117 129 17 186 40 47 25 27 0 0 1 0 0 0 0 0 0 31 1 0 0 81 COG0636(F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K) 133 112 120 118 9 16 33 20 20 24 9 30 13 35 38 32 41 31 41 49 38 31 81 47 38 22 37 50 44 21 44 63 61 49 137 168 46 172 42 48 22 21 0 0 0 0 2 0 0 0 0 17 1 0 0 45 COG1526(Uncharacterized protein required for formate dehydrogenase activity) 263 95 80 61 6 5 19 39 23 19 10 29 14 34 23 33 39 48 31 49 21 49 40 28 31 80 44 40 28 4 16 58 63 54 154 185 49 198 49 55 38 21 0 0 2 0 0 0 0 0 0 6 0 0 0 37 COG2244(Membrane protein involved in the export of O-antigen and teichoic acid) 464 49 139 40 27 6 17 25 36 12 26 21 12 18 19 11 30 31 19 23 38 43 54 25 21 19 37 44 19 4 20 65 54 31 106 158 97 220 38 75 25 19 0 1 0 0 0 0 0 0 0 6 0 0 0 25 COG0810(Periplasmic protein TonB, links inner and outer membranes) 456 180 195 109 11 10 24 31 17 13 20 10 16 55 35 16 30 20 23 22 31 23 63 38 43 19 38 26 32 21 17 62 55 21 122 88 53 94 39 26 9 15 0 0 0 0 0 0 2 0 2 22 0 0 0 14 NOG20245() 13 32 74 45 16 9 15 112 23 3 2 7 15 11 8 9 8 6 14 38 88 86 192 94 111 147 23 74 87 123 49 38 55 48 47 95 8 3 117 49 66 31 0 0 0 0 4 0 2 0 0 27 0 0 0 140 COG1981(Predicted membrane protein) 123 128 93 137 23 19 43 45 18 43 24 25 24 42 23 37 49 28 37 54 46 56 73 66 70 26 50 41 46 6 32 69 56 42 115 129 35 125 42 34 33 8 0 0 0 0 0 0 0 0 0 4 0 1 0 43 COG4231(Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits) 376 112 116 106 7 15 35 28 15 15 21 5 15 63 10 16 23 11 51 42 37 35 68 44 37 26 24 41 30 4 6 61 65 33 122 150 11 189 23 60 20 37 0 0 0 0 0 0 0 0 0 17 0 1 1 37 COG2132(Putative multicopper oxidases) 1298 41 63 30 9 16 7 17 9 3 8 8 8 49 22 9 33 28 17 10 14 8 25 8 19 72 18 4 6 9 6 14 13 12 13 41 43 211 5 8 2 4 0 0 0 0 0 0 0 0 0 12 0 0 0 9 COG1239(Mg-chelatase subunit ChlI) 149 41 28 65 14 18 16 24 18 10 8 12 7 39 21 12 27 51 19 31 65 33 114 65 69 75 17 44 47 39 63 82 41 50 116 75 21 386 64 60 19 41 0 0 0 3 0 0 0 0 0 37 2 1 0 22 COG3221(ABC-type phosphate/phosphonate transport system, periplasmic component) 309 92 64 90 14 32 57 14 9 2 5 18 0 19 34 21 13 11 20 22 54 43 107 52 65 33 43 37 40 21 32 55 35 33 50 96 44 390 38 49 11 11 0 0 0 0 1 0 0 0 0 17 0 2 0 52 COG1703(Putative periplasmic protein kinase ArgK and related GTPases of G3E family) 34 56 162 70 5 8 8 42 35 20 43 13 28 42 27 20 44 20 34 47 51 53 69 38 20 115 35 35 21 10 21 54 56 43 61 106 22 462 18 60 29 39 0 0 0 0 0 0 0 1 2 19 0 0 0 54 COG0733(Na+-dependent transporters of the SNF family) 124 138 202 92 16 8 29 31 16 11 27 6 30 54 33 14 5 2 33 49 65 64 111 56 58 12 44 32 55 29 48 67 75 20 102 107 43 123 42 48 37 26 0 0 0 0 0 0 0 0 0 30 0 0 0 30 COG4783(Putative Zn-dependent protease, contains TPR repeats) 235 109 130 79 12 17 30 48 9 17 18 14 28 47 10 22 39 28 39 23 28 19 75 33 32 24 24 35 27 9 23 63 49 42 143 90 45 377 25 41 13 24 2 1 0 0 0 1 0 0 0 18 0 0 0 25 COG0521(Molybdopterin biosynthesis enzymes) 121 84 126 82 9 11 15 38 18 13 16 28 21 47 20 38 49 51 37 41 19 34 59 30 33 103 23 29 18 9 16 58 55 62 143 198 42 241 56 46 30 15 2 1 0 0 0 0 0 1 0 16 0 0 0 36 COG2936(Predicted acyl esterases) 210 37 75 51 2 14 5 14 8 10 2 7 8 75 39 34 23 15 28 43 83 79 98 44 68 81 26 24 38 38 45 103 101 25 59 127 14 211 74 69 42 26 0 2 0 1 0 0 0 0 0 18 0 0 0 36 COG1214(Inactive homolog of metal-dependent proteases, putative molecular chaperone) 154 60 100 70 12 10 26 35 11 9 17 16 8 59 31 28 46 36 33 29 30 43 73 33 25 154 54 47 42 10 41 48 35 25 114 134 51 326 39 44 27 14 0 1 0 0 2 2 0 0 0 11 0 0 0 12 COG0535(Predicted Fe-S oxidoreductases) 255 63 76 94 7 11 20 55 9 5 19 22 18 52 11 24 47 61 27 36 49 47 77 46 55 66 35 42 29 36 44 67 44 24 75 127 106 205 30 39 11 13 0 0 0 1 0 0 0 0 0 11 2 0 0 30 COG2272(Carboxylesterase type B) 86 186 224 135 23 24 34 46 14 29 10 7 31 53 14 24 24 30 39 28 45 35 104 39 60 56 22 40 37 41 24 70 60 39 159 112 13 49 16 36 18 25 0 0 0 0 0 0 2 0 0 36 2 0 0 22 COG1961(Site-specific recombinases, DNA invertase Pin homologs) 410 57 39 50 13 21 14 20 17 13 48 17 12 75 28 14 57 25 42 14 38 25 47 38 30 47 24 33 35 39 46 25 25 20 34 32 176 432 8 15 6 9 0 0 0 0 0 0 0 0 2 23 0 0 0 27 COG3292(Predicted periplasmic ligand-binding sensor domain) 1191 77 82 23 24 1 5 20 11 9 12 6 0 12 10 11 15 14 29 12 15 27 39 18 7 20 30 23 18 8 3 29 44 17 49 52 56 128 20 19 11 9 0 0 0 0 0 0 0 0 0 6 0 0 0 9 COG1292(Choline-glycine betaine transporter) 279 156 196 85 24 10 20 48 35 29 18 17 45 62 14 12 4 8 46 76 40 41 39 19 24 7 31 16 20 17 7 68 23 19 92 85 19 349 34 32 10 16 0 0 0 0 0 0 0 0 0 11 0 0 0 14 COG4240(Predicted kinase) 123 124 80 163 9 5 36 37 11 8 18 17 2 6 29 23 16 24 22 40 67 50 97 54 65 32 32 37 58 13 62 93 71 56 196 165 54 22 57 40 22 29 2 0 0 0 0 0 0 0 0 17 0 1 0 32 COG3146(Uncharacterized protein conserved in bacteria) 219 94 78 92 8 25 30 31 11 20 11 10 17 57 33 15 20 12 20 46 35 33 90 41 68 23 42 27 43 36 40 82 59 30 142 118 25 258 53 37 24 18 0 0 0 0 0 0 0 0 0 18 0 0 0 25 COG4567(Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain) 188 111 94 110 3 7 33 34 18 19 7 26 15 17 25 26 32 34 29 52 41 44 63 47 44 26 31 36 32 1 35 81 74 56 159 224 32 91 31 48 31 45 1 0 0 0 0 0 0 0 2 26 0 0 0 35 COG0651(Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit) 94 58 68 87 18 52 39 14 6 4 8 13 6 45 21 14 3 9 28 50 26 25 69 26 42 15 60 37 34 6 25 87 40 52 132 148 38 513 51 36 18 19 0 0 0 2 0 2 2 0 0 17 0 0 0 46 COG3206(Uncharacterized protein involved in exopolysaccharide biosynthesis) 614 60 96 54 9 11 14 39 19 2 13 13 10 29 34 11 12 29 22 23 35 18 42 27 19 37 27 19 21 28 28 39 17 27 51 71 53 403 26 35 9 33 0 2 0 0 1 1 0 0 0 12 0 0 0 8 COG3509(Poly(3-hydroxybutyrate) depolymerase) 241 110 187 74 33 19 22 28 36 23 3 22 15 42 20 12 9 35 26 29 38 87 107 56 30 32 18 25 32 18 36 73 61 37 178 114 7 71 42 68 33 17 0 0 0 0 0 0 0 0 0 13 0 0 0 24 COG0496(Predicted acid phosphatase) 173 95 129 89 17 13 27 26 18 13 15 8 4 50 23 21 14 16 30 39 53 34 75 41 49 44 38 49 39 29 27 66 66 21 160 140 39 187 43 83 24 21 0 0 0 0 0 0 0 0 0 19 0 1 0 31 COG3380(Predicted NAD/FAD-dependent oxidoreductase) 109 44 48 67 10 13 40 41 19 11 21 35 7 42 15 33 37 54 38 30 56 40 72 48 46 70 59 65 40 7 44 62 81 50 163 90 27 253 45 39 28 7 0 0 0 0 2 0 5 1 0 28 0 0 0 53 COG0674(Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit) 77 92 223 99 6 7 42 4 20 0 10 6 9 64 38 26 29 11 42 60 35 73 100 60 54 62 41 62 39 4 27 46 53 36 59 116 72 197 16 21 40 40 0 0 0 2 0 0 0 0 0 7 0 0 0 62 COG0038(Chloride channel protein EriC) 524 52 47 49 16 22 8 10 10 16 21 6 15 63 4 8 21 20 42 10 41 26 55 32 52 31 18 33 28 15 39 39 38 20 47 67 39 453 73 33 11 10 0 0 0 2 0 0 0 0 0 12 0 0 0 9 COG0828(Ribosomal protein S21) 167 123 111 106 11 16 21 36 22 14 19 14 22 58 17 21 30 13 19 31 40 30 67 50 50 42 31 36 26 19 47 86 62 48 159 183 45 82 51 50 19 19 2 1 2 0 0 0 0 0 0 21 0 0 0 40 COG3276(Selenocysteine-specific translation elongation factor) 203 78 169 89 12 10 29 32 23 25 2 17 26 33 34 21 35 29 36 44 41 48 92 45 41 85 60 45 28 10 34 56 61 40 79 155 35 89 34 37 26 22 0 0 0 0 1 0 0 0 0 26 1 0 0 39 COG1267(Phosphatidylglycerophosphatase A and related proteins) 126 110 132 118 2 11 32 39 20 13 13 37 10 36 29 23 28 38 34 53 39 24 67 41 51 32 43 48 37 3 40 74 64 40 163 187 43 105 47 38 18 17 0 0 0 0 0 0 0 0 1 17 0 0 0 26 NOG20044(Sulfotransferase) 100 131 94 163 2 10 43 38 13 7 4 15 14 41 20 14 19 12 19 59 33 28 65 32 50 0 35 41 43 0 31 74 61 61 192 286 42 6 54 74 29 17 0 0 0 0 0 4 0 0 0 25 2 0 0 59 COG1215(Glycosyltransferases, probably involved in cell wall biogenesis) 622 33 56 45 16 11 9 18 5 10 17 11 6 39 4 7 44 21 14 23 35 14 42 37 29 50 15 25 32 22 44 51 34 9 45 35 101 426 45 21 7 5 0 0 0 0 0 0 0 0 0 14 0 0 0 12 COG4233(Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis) 208 156 141 107 4 12 34 26 16 8 42 7 10 44 22 32 8 9 35 32 22 30 45 37 46 29 41 16 38 13 15 65 50 35 125 99 93 268 22 33 27 16 0 0 0 0 0 0 0 2 0 23 0 0 0 17 COG2863(Cytochrome c553) 588 64 96 68 10 11 10 34 13 22 8 11 17 70 26 18 42 34 29 40 8 30 41 33 21 36 40 27 15 7 18 32 29 13 87 96 41 295 16 25 8 4 0 0 0 0 0 0 0 2 0 5 0 0 0 19 COG4395(Uncharacterized protein conserved in bacteria) 163 116 88 129 5 11 37 34 10 19 20 30 12 11 29 20 49 29 16 43 42 30 65 44 27 16 44 38 36 0 34 67 74 68 151 209 42 62 42 64 33 31 1 0 0 0 0 0 0 1 2 15 0 0 0 50 COG1305(Transglutaminase-like enzymes, putative cysteine proteases) 551 68 68 59 5 15 19 17 5 0 7 8 13 29 10 8 34 20 16 16 49 47 68 36 36 21 40 18 28 24 47 17 7 3 44 24 34 557 22 13 8 6 0 0 0 0 0 0 0 0 0 7 0 0 1 26 NOG20038(Pyridoxamine 5-phosphate oxidase) 150 153 130 148 6 10 50 53 18 15 5 17 12 22 20 24 25 35 15 27 41 48 81 34 56 26 31 34 32 4 33 63 75 51 154 184 30 69 31 38 21 17 0 0 0 0 0 0 0 1 0 24 0 1 0 34 NOG16378() 86 151 80 111 11 13 40 34 17 31 15 30 16 15 20 24 39 27 27 42 42 46 72 59 41 27 34 47 53 14 42 83 89 45 174 101 16 99 56 66 26 25 1 0 0 1 2 0 1 0 0 20 1 0 0 35 COG0218(Predicted GTPase) 129 78 144 90 13 9 29 30 14 18 7 11 11 53 32 28 28 28 32 32 34 28 50 33 32 36 42 34 33 19 21 77 56 57 189 128 48 193 47 75 19 32 0 1 0 0 0 1 0 0 0 9 0 0 2 31 COG1816(Adenosine deaminase) 237 71 118 86 6 6 21 25 13 5 4 12 9 52 25 26 45 46 33 31 31 18 38 23 31 153 35 33 24 7 18 57 51 30 59 191 25 291 26 31 24 14 0 0 0 0 0 0 0 0 0 20 0 0 0 39 COG0432(Uncharacterized conserved protein) 118 101 141 107 10 8 36 26 12 10 5 10 5 11 20 16 37 37 26 61 56 58 87 48 48 30 43 61 43 15 38 69 60 48 124 143 44 105 44 45 33 20 1 0 2 0 0 3 0 0 0 23 1 0 1 47 COG3436(Transposase and inactivated derivatives) 393 88 14 1 14 0 0 5 8 5 10 3 3 11 6 7 10 6 19 3 13 2 2 3 2 33 6 1 4 6 4 1 0 6 2 12 149 1276 0 0 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG1162(Predicted GTPases) 153 76 64 50 14 14 14 27 30 19 22 21 8 28 26 19 57 65 23 17 42 21 41 36 39 154 18 20 21 18 39 60 43 30 127 81 34 422 37 40 21 7 0 0 0 0 0 1 0 0 0 16 0 0 0 15 COG0722(3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase) 347 107 121 111 15 15 22 25 7 16 19 14 5 55 37 7 22 18 34 21 28 30 72 36 42 12 28 22 32 28 37 41 34 11 85 93 31 304 38 30 8 14 0 2 0 0 0 0 0 0 0 14 0 0 0 22 COG3319(Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases) 1975 2 16 5 1 0 0 0 0 0 0 0 0 12 0 0 2 4 2 0 4 2 1 0 0 3 0 0 1 1 3 1 2 2 4 0 10 52 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2710(Nitrogenase molybdenum-iron protein, alpha and beta chains) 105 43 15 70 10 8 10 8 15 4 13 2 5 63 0 11 29 7 24 21 68 31 80 44 65 25 25 37 39 63 55 100 47 62 116 60 23 493 78 36 14 16 0 3 0 0 0 0 0 1 0 22 0 0 0 27 COG4555(ABC-type Na+ transport system, ATPase component) 300 87 82 72 2 8 31 31 12 5 4 13 3 25 18 21 17 33 34 33 26 52 69 38 35 78 63 48 31 4 31 61 46 40 113 141 36 98 46 55 36 41 0 0 0 0 1 0 0 0 0 20 0 0 0 52 COG2046(ATP sulfurylase (sulfate adenylyltransferase)) 106 72 95 84 19 13 16 18 8 16 17 8 13 63 18 20 12 18 40 33 57 44 56 40 36 103 37 19 31 28 39 64 46 31 81 118 33 364 71 28 14 23 0 0 2 0 0 0 0 0 0 21 0 0 0 16 COG0364(Glucose-6-phosphate 1-dehydrogenase) 272 30 12 35 10 18 11 13 5 11 36 18 9 33 24 19 29 17 35 82 29 29 41 37 41 52 51 29 33 31 31 68 33 55 67 51 62 258 105 24 53 15 0 0 0 0 0 0 0 0 0 19 0 0 0 158 COG3279(Response regulator of the LytR/AlgR family) 227 93 86 75 20 9 22 31 25 13 28 20 17 44 22 23 40 44 40 39 18 35 60 26 40 65 51 11 27 7 29 71 61 47 120 107 41 190 37 41 16 19 0 0 0 0 0 0 0 0 0 16 0 0 0 34 COG2606(Uncharacterized conserved protein) 264 112 82 100 1 4 26 31 5 9 3 19 4 19 28 24 47 41 27 55 37 35 56 39 40 103 37 45 37 8 36 38 49 40 115 142 38 151 31 31 23 9 0 0 0 0 0 0 0 0 0 16 0 0 0 30 COG1174(ABC-type proline/glycine betaine transport systems, permease component) 219 60 53 95 1 5 28 26 9 12 2 12 16 22 15 51 35 41 29 27 34 19 35 23 15 42 22 18 16 2 28 47 43 35 84 127 20 596 53 19 5 14 0 0 0 0 0 0 0 0 4 11 0 0 0 16 NOG14600() 220 128 114 156 19 17 38 21 9 20 18 28 23 55 15 42 32 29 20 41 26 34 74 46 23 32 18 38 30 8 25 60 43 42 128 134 24 94 31 21 21 22 0 0 1 0 0 0 0 0 0 19 0 0 0 35 COG1391(Glutamine synthetase adenylyltransferase) 229 30 36 24 5 11 11 23 12 16 30 9 13 39 10 11 58 53 36 16 8 12 28 11 13 49 51 18 7 7 2 48 33 26 97 65 65 740 21 38 14 18 0 0 0 0 0 0 0 0 0 14 0 0 0 14 COG0373(Glutamyl-tRNA reductase) 177 100 102 81 12 10 23 20 16 23 28 15 11 52 27 22 38 30 28 21 54 33 55 37 49 70 24 22 36 25 43 54 39 32 120 136 38 225 24 35 25 13 0 0 0 0 1 0 1 0 0 19 0 0 0 24 COG0310(ABC-type Co2+ transport system, permease component) 166 86 96 83 6 5 39 24 14 10 9 19 4 28 19 27 54 67 22 33 45 40 86 43 37 96 42 61 37 6 30 43 46 45 124 145 37 105 38 58 26 8 2 0 0 0 0 0 0 0 0 7 0 0 1 45 COG1051(ADP-ribose pyrophosphatase) 311 88 114 63 13 8 25 30 15 8 6 12 13 42 23 18 21 26 19 41 28 41 66 38 37 49 37 31 36 26 28 42 55 27 73 94 63 247 21 36 28 13 0 0 0 0 0 0 0 0 0 12 1 0 0 37 COG5278(Predicted periplasmic ligand-binding sensor domain) 1467 33 26 9 6 5 6 5 1 4 8 3 0 18 2 3 18 26 5 3 6 7 15 5 10 24 14 9 5 8 7 10 11 2 8 13 20 206 8 12 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG0718(Uncharacterized protein conserved in bacteria) 135 76 84 120 10 8 33 34 12 18 17 23 8 27 16 22 24 38 34 45 45 18 69 36 51 30 23 44 51 14 48 59 67 41 133 161 23 150 38 50 24 20 0 3 0 0 0 0 0 0 0 29 1 1 0 39 COG3022(Uncharacterized protein conserved in bacteria) 132 100 144 74 10 18 31 30 21 21 22 13 12 36 32 21 37 35 27 33 18 45 62 27 30 32 29 26 26 10 18 67 59 44 144 116 36 224 41 52 26 30 0 0 0 0 1 0 1 0 0 18 0 0 0 21 COG2017(Galactose mutarotase and related enzymes) 392 51 57 61 9 13 21 26 9 19 7 10 17 35 15 16 34 47 26 24 42 29 64 35 37 111 35 47 44 13 20 58 40 29 135 78 26 122 66 40 17 15 0 0 1 0 0 1 1 0 0 14 0 3 0 29 COG1296(Predicted branched-chain amino acid permease (azaleucine resistance)) 204 71 41 66 4 10 22 27 11 9 16 27 5 27 26 30 57 72 28 46 30 22 45 29 25 116 28 17 25 2 14 61 47 41 94 128 35 335 42 37 17 12 0 0 0 0 0 2 0 0 0 13 0 0 2 21 COG0605(Superoxide dismutase) 142 46 54 53 15 17 22 29 18 15 28 14 15 39 23 16 33 37 21 17 19 29 39 27 34 123 24 24 31 14 22 49 54 40 165 90 63 375 21 42 17 20 0 0 0 0 0 0 0 3 2 36 2 0 1 19 NOG25632() 119 60 106 64 10 9 42 15 29 10 20 14 18 24 12 18 8 9 18 20 24 57 83 30 43 73 50 76 34 4 31 60 93 75 182 159 17 59 20 92 30 28 0 0 0 0 2 0 0 0 0 45 0 0 0 47 NOG39259() 90 150 69 152 3 6 34 59 10 11 6 17 15 3 18 46 26 29 12 33 35 49 51 34 39 25 34 43 37 1 39 68 74 45 207 243 18 3 45 36 17 32 0 0 1 1 0 0 0 0 0 30 0 1 0 41 COG2206(HD-GYP domain) 1439 39 62 17 2 2 0 0 3 0 14 4 2 27 4 2 15 6 12 9 11 7 24 5 9 40 18 10 14 9 8 9 0 2 10 5 93 90 2 2 5 0 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG5498(Predicted glycosyl hydrolase) 931 15 38 19 44 16 28 36 13 22 44 8 14 23 14 4 9 10 17 31 27 52 41 15 33 7 30 35 14 6 13 32 20 19 116 44 27 41 24 56 15 18 0 0 2 0 0 0 0 0 0 5 0 0 0 6 COG0806(RimM protein, required for 16S rRNA processing) 122 82 99 86 16 14 38 16 7 19 13 13 13 50 7 16 27 23 22 25 43 41 64 42 42 81 34 21 27 9 42 57 51 29 119 89 37 338 36 45 12 16 0 1 0 0 0 0 0 0 0 18 0 2 0 26 NOG35990() 121 93 200 75 11 5 46 22 18 17 18 31 14 39 26 19 20 27 36 57 31 63 68 26 38 28 34 48 26 5 31 77 53 49 124 172 24 27 18 77 25 31 0 0 0 0 4 0 0 0 0 23 0 0 0 31 COG1286(Uncharacterized membrane protein, required for colicin V production) 139 110 93 120 1 11 29 45 13 10 17 16 4 49 28 18 26 40 23 41 25 33 43 30 33 28 29 35 33 3 41 66 56 41 149 180 35 155 23 39 24 32 0 0 0 2 0 0 0 0 0 20 0 0 0 39 COG1477(Membrane-associated lipoprotein involved in thiamine biosynthesis) 182 81 120 55 12 10 38 21 26 13 13 9 19 40 36 16 46 30 33 38 25 33 67 36 28 59 42 48 21 12 18 47 39 21 121 94 54 301 22 40 15 10 0 0 0 0 0 0 0 0 0 18 0 0 2 14 COG3209(Rhs family protein) 1498 5 4 1 0 1 1 26 4 4 10 0 4 12 0 3 20 10 3 1 3 8 9 0 0 12 4 2 7 3 1 11 3 0 12 5 177 147 2 4 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG2771(DNA-binding HTH domain-containing proteins) 1329 27 13 23 6 3 2 8 6 4 4 3 13 13 8 11 10 5 10 4 9 7 31 16 16 7 7 6 13 3 17 23 18 10 46 17 40 177 17 15 4 5 0 0 0 0 0 0 0 0 0 7 0 0 0 3 COG2940(Proteins containing SET domain) 158 94 103 107 26 32 40 49 15 12 9 15 14 20 12 32 50 46 23 38 35 24 56 31 41 30 30 47 36 28 29 50 60 41 116 145 52 61 47 50 25 9 0 0 2 1 0 0 0 2 0 22 0 0 0 46 COG1090(Predicted nucleoside-diphosphate sugar epimerase) 166 47 55 56 11 4 16 29 14 9 15 23 12 37 22 15 46 42 30 34 54 48 60 46 32 127 38 29 41 21 33 60 36 14 37 113 34 313 49 42 17 13 0 1 0 0 0 0 0 0 2 25 1 0 0 41 COG3820(Uncharacterized protein conserved in bacteria) 87 121 82 115 1 8 33 43 18 6 8 16 30 60 19 24 35 13 31 36 54 34 57 45 41 21 34 40 31 8 32 55 69 50 164 184 36 70 37 52 20 24 0 0 1 0 0 0 0 0 1 18 0 0 0 45 COG1134(ABC-type polysaccharide/polyol phosphate transport system, ATPase component) 183 48 77 60 8 19 28 16 8 13 8 3 7 24 8 20 72 58 31 35 26 35 59 42 42 128 35 29 12 12 27 44 31 20 74 83 59 396 31 28 18 13 0 0 1 2 0 0 0 0 0 7 0 0 0 26 COG1112(Superfamily I DNA and RNA helicases and helicase subunits) 339 41 82 44 20 25 6 15 8 6 19 9 6 34 9 19 32 51 35 19 17 27 37 20 24 78 28 23 18 21 10 35 53 26 31 73 28 489 13 35 25 16 0 0 0 0 0 0 0 0 0 8 0 2 0 49 COG1721(Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)) 160 48 148 51 13 14 17 19 24 5 13 14 8 51 32 25 21 18 31 46 32 55 66 31 37 35 38 34 23 17 25 40 49 31 73 110 66 284 29 52 31 28 0 3 2 0 0 0 0 0 0 16 0 0 0 38 COG2409(Predicted drug exporters of the RND superfamily) 103 24 70 20 11 3 17 5 0 1 8 0 0 25 10 8 145 158 18 18 10 21 47 22 9 387 25 8 18 2 7 25 28 16 16 45 8 565 8 26 16 14 0 0 0 0 0 0 0 0 0 5 0 0 0 28 COG0614(ABC-type Fe3+-hydroxamate transport system, periplasmic component) 316 50 81 69 3 5 18 18 12 12 13 11 15 31 29 22 24 23 14 24 32 37 57 33 39 121 34 39 30 7 20 58 52 32 55 87 41 228 42 40 31 24 0 4 0 0 0 0 0 0 0 12 0 0 0 51 COG1120(ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components) 536 34 68 41 8 6 5 10 16 4 10 9 6 58 10 11 46 46 16 16 14 22 43 22 24 101 36 27 22 5 22 35 36 22 55 64 23 299 37 55 17 16 2 1 2 0 0 0 0 0 0 9 0 0 0 28 NOG26616() 26 26 37 38 9 35 9 45 17 15 18 12 9 68 11 11 23 39 71 35 13 54 29 15 22 112 48 59 8 12 20 49 37 42 131 69 13 520 22 72 32 22 2 0 4 0 0 0 0 0 0 23 0 0 0 9 COG0314(Molybdopterin converting factor, large subunit) 182 69 113 70 1 9 12 42 28 17 8 23 5 14 16 28 24 37 27 49 36 28 50 23 26 62 41 32 21 6 21 68 51 31 142 190 34 178 35 57 20 12 0 0 0 1 0 0 0 2 0 13 0 0 0 39 COG2146(Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases) 533 47 86 49 4 4 18 22 9 10 2 3 10 39 22 17 36 42 19 39 42 26 33 24 33 110 23 18 22 5 14 19 22 8 37 65 40 350 21 12 8 12 0 0 0 0 0 0 0 0 0 16 0 1 0 15 COG2176(DNA polymerase III, alpha subunit (gram-positive type)) 119 37 72 44 4 2 30 15 22 14 21 30 11 39 19 23 60 55 24 21 19 31 56 29 30 141 31 26 29 1 15 54 44 21 101 97 53 380 30 65 21 11 0 0 0 0 0 0 0 0 0 15 0 0 0 17 COG4774(Outer membrane receptor for monomeric catechols) 864 90 171 97 17 0 36 19 2 9 16 11 12 20 7 9 8 10 12 26 27 27 38 10 24 7 29 14 14 5 14 33 22 24 87 40 14 35 14 22 11 9 0 0 0 0 0 0 0 0 0 3 0 0 0 13 COG5352(Uncharacterized protein conserved in bacteria) 85 121 78 109 3 14 39 47 16 14 10 16 13 32 16 23 21 21 19 40 35 39 52 43 56 33 26 44 40 0 40 70 72 53 157 195 22 63 38 34 23 29 2 0 0 0 0 0 0 0 0 26 0 0 0 40 COG5265(ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components) 466 30 26 40 12 32 13 62 25 31 19 25 18 56 19 9 16 21 34 12 22 16 39 29 24 23 19 25 21 10 16 41 36 22 69 65 40 380 19 24 14 13 0 0 0 0 0 1 0 0 0 12 0 0 0 21 COG1127(ABC-type transport system involved in resistance to organic solvents, ATPase component) 241 33 36 54 20 14 26 27 14 9 14 10 11 31 17 21 31 38 27 22 31 29 57 44 29 76 29 39 34 20 42 45 43 21 99 68 45 353 32 48 22 26 0 0 1 1 0 0 0 0 0 17 0 0 0 18 COG0262(Dihydrofolate reductase) 125 70 88 62 15 21 35 38 20 15 23 16 32 60 27 20 28 43 31 35 30 31 77 24 45 49 19 43 30 10 21 56 54 44 100 141 80 143 29 45 23 16 0 0 1 0 0 0 0 0 0 23 0 0 1 25 COG1752(Predicted esterase of the alpha-beta hydrolase superfamily) 673 40 58 24 18 4 3 38 9 2 19 5 24 44 7 10 37 41 19 10 8 9 32 10 10 46 13 17 7 3 13 6 6 6 14 62 42 527 4 6 12 2 1 0 1 0 0 0 0 0 0 7 0 0 0 12 COG3452(Predicted periplasmic ligand-binding sensor domain) 1270 26 14 15 6 6 1 4 1 4 2 1 2 32 6 6 14 35 8 2 6 5 14 13 17 37 3 2 9 9 7 10 9 4 7 8 44 287 4 2 1 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG0709(Selenophosphate synthase) 142 30 123 49 12 13 21 25 10 10 13 14 8 48 19 19 26 17 26 22 54 49 92 55 33 24 45 52 51 23 54 44 31 25 73 84 12 345 52 28 17 12 0 2 0 0 1 0 0 0 0 23 0 1 0 27 COG0076(Glutamate decarboxylase and related PLP-dependent proteins) 266 34 103 49 6 17 12 6 10 8 7 6 12 37 7 12 48 60 34 30 48 30 74 26 29 167 27 15 30 23 41 41 50 16 56 95 17 277 36 28 15 16 0 3 0 0 0 0 0 0 0 16 0 0 0 14 COG1100(GTPase SAR1 and related small G proteins) 93 52 84 96 51 76 16 5 4 4 9 3 6 11 18 11 27 29 21 24 106 63 123 68 68 30 18 23 60 146 60 62 28 22 45 51 47 148 68 19 9 11 2 1 0 0 0 4 0 0 0 12 0 0 0 20 NOG10056() 44 97 107 72 10 13 37 26 32 18 13 17 6 53 14 24 51 47 45 22 23 25 47 40 25 6 33 43 24 12 21 68 50 41 161 102 46 294 30 51 11 23 0 0 0 0 0 0 0 0 0 14 0 0 0 14 COG1067(Predicted ATP-dependent protease) 324 50 86 22 6 6 8 11 1 5 6 9 1 44 6 17 39 54 18 21 25 26 38 20 26 51 31 32 9 5 17 46 30 20 41 58 80 529 21 33 35 12 0 0 0 0 0 0 0 0 0 10 0 0 0 18 COG1957(Inosine-uridine nucleoside N-ribohydrolase) 160 43 73 71 10 7 24 26 13 5 4 11 16 61 24 42 60 71 38 50 40 34 62 35 22 128 45 35 27 0 17 72 35 51 85 151 25 65 42 46 26 18 0 0 0 0 0 0 0 0 0 16 0 0 0 60 COG1732(Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)) 262 79 63 93 1 10 27 44 9 17 8 13 17 12 15 41 21 21 27 29 35 30 34 23 27 11 23 15 17 2 28 46 47 29 83 156 16 425 28 18 7 14 0 2 0 0 0 0 0 0 0 4 0 0 0 17 COG1125(ABC-type proline/glycine betaine transport systems, ATPase components) 406 36 57 43 15 7 19 13 10 12 11 14 9 21 9 16 16 38 19 22 47 22 57 29 30 43 35 20 17 10 24 37 30 34 85 58 28 440 29 26 10 12 0 0 0 0 0 0 2 0 0 7 0 0 0 15 NOG11123() 83 104 76 114 0 7 41 48 19 19 10 24 12 13 28 25 36 20 20 44 42 34 68 43 48 24 48 44 26 1 33 60 66 44 159 177 31 53 41 50 24 25 0 0 0 1 0 1 0 0 0 24 1 1 0 28 COG2871(Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF) 135 104 114 72 15 11 54 25 18 12 23 11 22 34 16 14 3 12 23 35 24 46 52 35 45 15 29 55 27 4 28 53 48 50 164 118 39 177 21 61 20 26 0 0 0 0 0 0 0 0 0 19 0 1 0 21 COG2867(Oligoketide cyclase/lipid transport protein) 145 91 90 119 3 9 24 35 7 16 21 29 5 34 36 23 26 32 30 25 31 26 51 40 35 28 29 42 27 0 25 56 53 48 154 144 31 127 42 50 14 28 0 0 0 0 0 1 0 0 0 21 0 0 0 27 COG2887(RecB family exonuclease) 13 9 28 22 4 1 14 18 23 2 8 8 14 28 20 20 83 60 14 16 14 30 26 18 32 159 34 40 10 2 12 25 48 24 64 79 17 760 24 32 18 13 0 0 0 0 0 0 0 0 0 16 0 0 1 26 COG0746(Molybdopterin-guanine dinucleotide biosynthesis protein A) 199 93 73 74 2 2 11 30 10 16 8 19 11 17 27 26 25 25 21 38 22 37 34 23 21 44 36 25 18 1 19 45 36 38 119 156 30 340 44 49 10 9 0 2 1 0 0 0 0 0 0 11 0 0 0 28 COG3268(Uncharacterized conserved protein) 258 120 188 102 10 10 42 36 31 8 11 18 12 47 16 24 5 2 23 32 19 37 59 22 35 6 33 27 32 22 13 61 44 37 132 118 17 56 27 50 21 18 0 0 0 0 0 0 0 1 0 22 1 0 0 18 COG3180(Putative ammonia monooxygenase) 71 98 42 88 3 21 37 41 11 20 6 26 10 26 24 24 20 9 18 34 51 28 75 60 52 5 52 41 45 15 26 46 68 43 113 132 21 234 44 39 28 13 0 0 0 0 0 0 0 0 0 16 0 1 2 35 COG2159(Predicted metal-dependent hydrolase of the TIM-barrel fold) 138 60 204 114 7 16 8 26 9 8 30 18 11 97 30 38 35 37 42 40 49 46 74 34 57 77 31 16 22 8 11 43 26 16 32 120 60 139 23 12 15 4 0 0 0 2 0 0 0 0 0 4 1 0 0 22 NOG19065() 82 105 82 105 5 15 22 38 14 5 7 13 4 23 18 10 38 34 12 32 43 42 54 42 37 124 31 33 24 2 34 60 63 44 130 247 28 44 41 39 29 16 0 0 2 0 0 0 0 0 0 20 1 0 0 15 NOG17946(Phosphate-Starvation-Inducible protein) 134 105 69 115 4 14 45 38 14 21 10 21 8 14 12 24 13 11 14 34 40 38 91 48 33 10 30 33 45 6 34 76 81 60 176 107 30 0 43 64 32 27 0 0 0 0 0 0 0 2 0 36 0 0 0 41 COG1615(Uncharacterized conserved protein) 47 29 39 20 4 2 20 7 8 2 4 5 3 42 14 26 103 116 35 32 22 16 40 28 29 293 33 33 15 3 9 41 28 27 27 125 7 403 49 19 20 12 0 0 0 0 0 0 0 0 0 17 0 0 0 47 NOG13248() 119 105 63 93 2 10 31 48 9 15 11 11 12 16 24 32 33 31 10 36 21 23 58 27 41 18 47 40 26 3 32 62 76 61 148 132 37 130 42 43 32 23 3 0 0 0 0 0 0 2 0 24 0 0 0 37 COG0363(6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase) 149 49 79 45 10 8 22 18 13 14 25 17 12 44 29 24 28 26 22 27 27 35 58 34 47 57 33 48 35 27 34 65 35 35 76 109 37 241 52 59 23 11 0 1 0 0 0 0 0 0 0 19 0 0 0 37 COG1505(Serine proteases of the peptidase family S9A) 228 113 171 93 14 15 29 19 19 8 8 3 6 20 14 21 7 17 18 25 19 24 55 33 50 45 26 35 21 28 11 76 57 22 122 75 23 186 24 42 22 24 0 0 0 0 0 0 0 1 0 13 0 0 0 13 COG4796(Type II secretory pathway, component HofQ) 292 76 106 83 5 6 6 28 6 19 12 36 10 21 30 15 31 21 27 24 43 32 61 41 35 55 44 34 32 6 27 26 24 14 39 116 86 233 22 20 10 8 0 0 0 0 0 0 0 0 0 14 0 0 0 19 NOG06022() 46 147 271 110 14 7 25 15 7 18 0 25 15 37 15 15 13 14 25 50 39 28 64 24 47 112 29 27 23 13 19 75 64 57 115 87 7 52 28 66 15 15 0 0 0 0 0 2 0 0 0 4 0 0 0 14 COG1165(2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase) 134 41 42 73 24 15 14 28 8 9 14 9 10 18 14 11 67 68 19 18 45 34 95 37 59 171 16 8 22 19 40 48 21 21 61 69 17 352 53 25 8 3 0 0 0 0 0 0 0 0 0 16 0 1 0 9 COG0450(Peroxiredoxin) 304 82 73 78 8 11 15 13 9 5 14 11 9 29 14 17 29 41 26 19 32 38 63 41 34 92 22 14 26 13 24 30 20 10 36 155 55 282 20 9 8 13 0 0 0 0 0 0 0 0 0 11 2 0 0 25 COG3785(Uncharacterized conserved protein) 91 116 76 121 4 8 32 42 13 21 10 17 5 31 17 20 21 20 22 36 30 26 75 54 38 16 34 34 32 2 28 57 65 61 170 171 33 69 30 31 17 23 0 1 0 0 0 0 0 0 0 24 0 1 0 36 COG2249(Putative NADPH-quinone reductase (modulator of drug activity B)) 208 97 73 98 12 6 36 42 17 14 10 29 16 7 31 29 19 18 20 30 33 28 53 27 45 33 27 36 24 3 17 59 55 42 133 161 29 72 34 44 20 24 0 0 0 0 0 0 0 0 2 34 0 0 0 27 COG0609(ABC-type Fe3+-siderophore transport system, permease component) 500 19 29 22 4 3 1 6 1 6 11 3 0 25 12 8 28 18 9 8 12 5 16 10 9 141 15 12 21 12 16 59 43 24 101 87 38 392 31 41 22 20 0 3 0 0 0 0 0 0 0 19 0 0 0 12 COG4521(ABC-type taurine transport system, periplasmic component) 155 86 68 116 1 9 39 60 13 18 17 27 13 20 33 39 19 23 25 41 36 41 60 34 25 2 50 30 42 1 28 69 62 76 142 150 42 4 35 22 17 21 0 0 0 0 0 0 2 0 0 17 0 0 0 36 COG2256(ATPase related to the helicase subunit of the Holliday junction resolvase) 142 43 54 43 9 6 14 16 28 20 26 7 17 62 24 14 36 46 50 12 41 18 60 17 33 78 27 18 28 21 31 46 43 24 68 73 42 368 63 37 9 13 2 0 0 0 0 0 0 0 0 7 0 0 3 26 COG0286(Type I restriction-modification system methyltransferase subunit) 375 58 57 43 7 3 11 23 17 4 6 20 5 28 15 10 43 23 21 28 32 8 59 23 42 105 18 19 15 11 25 22 18 21 56 74 57 341 19 26 7 12 0 0 4 0 0 0 0 0 0 9 0 0 0 41 COG4327(Predicted membrane protein) 92 122 91 112 11 5 36 31 13 24 22 19 15 45 7 29 22 24 21 46 30 34 55 43 34 21 27 44 41 4 28 59 52 34 157 119 52 72 23 33 21 20 2 0 0 0 1 0 0 0 0 22 0 0 0 40 COG3476(Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)) 44 83 52 93 4 9 19 29 13 24 13 18 14 19 15 14 41 68 22 29 25 35 65 36 17 55 30 38 42 7 25 77 51 60 164 121 54 121 46 56 27 22 0 0 0 2 0 0 0 1 0 26 0 0 0 26 NOG13798() 54 67 78 61 4 15 33 17 10 6 14 11 13 57 14 10 3 4 32 37 27 39 53 43 46 9 40 25 34 9 16 73 85 50 183 181 31 81 61 72 26 36 0 1 1 0 0 0 0 0 0 37 0 0 1 51 COG0058(Glucan phosphorylase) 195 27 25 47 5 13 6 7 3 5 0 1 6 6 8 3 16 18 16 28 57 55 92 59 87 29 21 36 27 55 52 43 29 19 18 24 28 522 54 20 21 12 0 0 0 0 0 0 0 0 2 18 0 0 0 35 NOG14463() 21 59 152 36 35 7 30 30 25 4 23 17 16 24 25 22 12 20 31 74 53 59 79 42 37 2 31 36 46 7 29 97 78 40 157 155 15 20 26 65 48 25 0 0 0 0 0 0 0 0 0 12 0 0 0 27 NOG04272() 28 48 141 68 55 8 49 21 30 10 23 35 13 19 20 9 17 18 24 32 36 38 61 28 37 11 23 66 30 9 24 81 73 78 194 145 16 30 20 71 22 36 0 0 0 0 0 0 0 0 0 14 0 0 0 36 COG0120(Ribose 5-phosphate isomerase) 131 101 110 78 5 13 27 27 17 15 7 6 11 57 17 14 39 28 22 31 33 25 70 28 23 27 23 26 30 32 18 65 48 36 105 99 33 240 28 26 18 17 0 0 0 0 0 0 0 2 0 14 0 0 0 20 COG1749(Flagellar hook protein FlgE) 250 40 24 24 13 16 21 14 7 7 4 10 6 51 14 8 12 19 20 20 29 34 42 33 40 27 37 37 28 11 23 65 38 35 120 64 38 388 31 69 11 13 0 0 0 0 0 0 0 0 0 20 0 0 0 24 COG2326(Uncharacterized conserved protein) 183 90 148 67 11 18 28 20 13 25 17 2 2 20 14 11 12 12 13 24 23 30 57 26 26 35 33 22 17 14 16 34 36 31 48 71 14 435 37 35 12 20 0 0 0 0 0 0 0 0 0 13 0 0 0 18 COG1279(Lysine efflux permease) 200 73 89 88 3 6 30 39 14 25 6 20 2 25 22 37 27 31 23 30 25 30 61 43 50 4 23 23 17 3 24 54 48 31 141 145 38 98 37 45 21 21 1 0 1 0 0 0 0 0 0 16 0 0 0 43 COG5319(Uncharacterized protein conserved in bacteria) 109 102 70 102 3 3 23 43 8 10 15 24 8 20 30 18 34 39 28 43 44 30 68 33 33 15 27 42 29 4 21 54 70 53 174 162 21 44 41 33 14 28 1 0 0 0 1 0 0 0 0 17 0 0 0 39 COG3605(Signal transduction protein containing GAF and PtsI domains) 212 39 47 30 7 12 7 20 21 19 35 11 15 65 11 23 20 31 49 21 15 22 31 21 16 38 23 26 19 5 12 30 40 26 60 55 60 548 22 22 7 11 0 0 0 0 0 0 0 0 0 2 0 0 0 23 COG2267(Lysophospholipase) 303 84 77 59 13 8 17 17 19 19 15 15 4 62 16 21 10 19 40 25 18 27 58 20 28 15 25 47 31 4 25 48 39 40 96 76 22 208 34 38 28 14 0 0 0 0 0 0 0 0 0 16 0 0 0 28 COG2096(Uncharacterized conserved protein) 87 43 98 61 13 13 23 18 17 12 17 8 10 33 21 18 52 43 21 24 31 45 69 43 30 148 25 54 24 7 18 47 60 27 68 105 39 200 27 40 15 13 0 0 0 0 0 0 0 0 0 13 0 0 0 45 COG0369(Sulfite reductase, alpha subunit (flavoprotein)) 369 39 42 32 11 10 11 7 4 7 12 1 10 25 4 2 13 14 8 35 41 59 62 45 38 15 14 30 36 27 37 78 80 33 56 51 9 158 54 75 25 27 0 0 0 2 3 3 0 0 2 53 0 0 0 56 COG2166(SufE protein probably involved in Fe-S center assembly) 85 46 101 68 19 7 22 30 12 13 13 16 9 41 14 29 15 16 23 25 52 46 80 41 23 12 25 31 35 14 32 47 41 40 101 100 33 267 53 42 32 17 0 0 0 0 0 0 0 0 0 14 0 0 0 42 NOG06830(Beta-1,4-Mannosyl-Glycoprotein 4-beta-N-acetylglucosaminyltransferase) 80 109 72 113 3 2 29 39 18 3 3 8 4 19 10 21 32 27 18 37 48 43 63 63 53 67 26 40 43 8 46 59 70 49 151 129 21 38 39 34 24 19 0 0 0 0 0 0 1 0 1 9 0 0 0 33 COG1566(Multidrug resistance efflux pump) 976 23 25 21 1 7 5 16 10 6 8 8 6 35 13 8 12 6 13 11 16 9 20 16 5 10 30 11 9 5 11 29 15 19 33 33 23 244 20 20 5 12 0 0 0 0 0 0 0 0 0 6 1 0 0 11 COG3971(2-keto-4-pentenoate hydratase) 561 36 42 51 8 13 9 42 20 21 9 7 14 32 24 17 27 35 22 21 25 19 43 25 35 31 32 21 12 2 12 45 31 42 69 83 10 150 25 33 16 10 0 0 0 0 0 0 0 0 0 8 0 0 0 33 NOG13555() 47 65 96 60 8 6 29 24 12 9 18 24 15 21 21 32 54 24 28 28 40 24 47 18 27 64 46 33 27 9 13 56 42 53 153 151 20 176 39 53 20 25 0 0 0 0 1 0 2 2 0 23 0 1 0 33 COG3494(Uncharacterized protein conserved in bacteria) 82 82 68 120 8 14 31 46 11 9 21 15 3 13 19 16 16 25 23 52 34 30 51 55 41 27 34 38 37 1 26 63 58 47 152 183 36 86 25 40 20 15 0 0 0 0 0 0 0 1 0 17 0 0 0 27 COG0632(Holliday junction resolvasome, DNA-binding subunit) 136 37 86 45 14 12 13 22 15 7 14 11 7 58 16 10 57 52 22 18 27 30 70 23 40 106 17 12 33 17 21 43 38 25 75 79 50 313 39 38 17 21 0 0 0 0 0 0 2 0 0 13 1 0 0 14 COG1989(Type II secretory pathway, prepilin signal peptidase PulO and related peptidases) 215 75 125 88 4 4 29 32 7 20 11 21 5 26 21 9 33 34 17 30 22 31 64 32 34 52 27 25 39 19 24 29 34 18 79 109 62 219 21 13 5 13 0 1 0 0 0 0 1 0 1 16 0 0 0 18 COG0684(Demethylmenaquinone methyltransferase) 175 105 121 95 8 23 29 19 13 11 17 8 9 52 23 23 25 25 37 26 26 23 55 39 24 31 39 34 29 5 22 63 36 34 112 102 36 113 37 33 14 17 0 0 0 1 0 0 1 0 0 18 0 0 0 23 COG0543(2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases) 350 65 91 60 13 9 2 21 11 2 24 14 7 57 23 25 50 68 29 21 2 18 17 12 11 121 30 22 11 11 5 22 46 20 55 82 65 247 12 21 16 7 0 0 0 0 0 0 0 0 0 5 0 0 0 10 COG4644(Transposase and inactivated derivatives, TnpA family) 1576 58 13 4 0 0 0 0 0 0 19 2 0 15 0 0 2 4 1 2 4 0 2 0 2 4 12 0 8 6 6 0 2 0 2 3 21 19 3 2 0 2 0 0 0 0 0 0 0 0 0 7 0 0 0 1 COG1236(Predicted exonuclease of the beta-lactamase fold involved in RNA processing) 191 38 55 42 16 17 11 10 4 4 1 7 3 14 18 10 40 25 16 20 42 40 84 31 61 48 27 20 35 16 32 41 27 27 35 49 47 448 38 32 14 19 0 0 0 0 0 0 0 0 0 14 1 0 0 30 COG1666(Uncharacterized protein conserved in bacteria) 140 58 69 76 4 9 44 33 14 14 23 21 17 26 21 21 71 59 24 34 29 29 58 33 29 120 40 36 35 15 30 37 37 32 99 83 29 75 50 31 14 13 0 0 0 0 0 0 1 1 2 21 1 0 0 32 COG2062(Phosphohistidine phosphatase SixA) 172 134 118 121 9 11 40 14 11 7 11 11 6 19 4 11 11 22 16 35 43 40 68 34 40 22 24 27 26 6 6 60 35 19 83 55 22 294 27 37 5 13 0 0 0 0 0 0 0 0 0 10 0 0 0 10 COG2081(Predicted flavoproteins) 167 20 20 31 7 21 10 66 37 25 34 42 29 74 36 54 62 43 53 17 40 27 31 22 26 25 28 20 15 17 21 45 33 29 44 48 54 270 56 30 11 10 0 0 0 0 0 0 0 0 0 12 0 0 0 26 COG4121(Uncharacterized conserved protein) 291 43 43 37 10 12 11 9 10 12 19 11 22 47 9 7 10 13 19 26 45 36 59 35 19 12 34 24 15 19 18 54 32 15 106 61 29 417 31 27 9 7 0 0 0 0 0 1 0 0 0 5 0 0 0 12 COG0692(Uracil DNA glycosylase) 125 50 78 50 10 10 26 20 25 5 13 16 13 29 10 28 60 55 25 23 14 23 44 29 17 112 25 30 22 4 8 56 32 15 118 80 35 308 31 40 20 13 0 0 2 0 0 0 0 2 2 14 0 0 0 16 COG3852(Signal transduction histidine kinase, nitrogen specific) 273 63 61 64 4 17 22 17 13 31 21 9 5 43 18 10 14 22 28 37 12 28 36 19 23 33 27 18 25 3 19 51 49 22 89 98 39 255 22 73 9 20 0 0 0 0 0 0 0 1 0 17 0 0 0 22 COG1805(Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB) 125 84 115 51 23 10 43 25 21 15 14 11 23 28 23 16 6 9 32 27 43 26 66 25 23 1 27 32 23 8 21 47 51 50 109 124 22 239 38 43 17 14 0 0 0 2 0 0 0 0 0 19 0 1 0 8 COG2071(Predicted glutamine amidotransferases) 310 51 86 76 5 10 15 18 8 12 10 7 21 38 15 13 26 22 20 37 23 26 50 34 39 102 43 22 29 2 26 42 39 32 77 109 14 141 22 38 13 9 0 0 0 0 0 0 0 0 0 19 0 0 2 26 COG3419(Tfp pilus assembly protein, tip-associated adhesin PilY1) 414 68 90 90 2 3 23 43 15 10 9 29 20 18 12 16 5 20 13 23 37 29 55 60 30 11 64 40 39 1 33 12 20 30 80 131 53 47 12 13 4 5 0 0 0 0 0 0 0 0 0 24 0 0 0 26 COG3565(Predicted dioxygenase of extradiol dioxygenase family) 82 91 94 86 10 9 21 33 13 16 14 21 4 19 20 30 22 32 25 36 16 35 68 32 29 12 37 32 14 8 18 62 87 51 162 136 15 103 35 44 25 15 0 0 0 0 0 0 1 1 0 21 0 0 0 41 NOG06253() 113 145 179 92 6 9 28 44 14 26 8 13 18 42 14 13 18 3 17 20 30 39 89 43 37 22 39 17 50 17 18 55 63 26 98 121 10 50 17 23 21 24 0 0 2 1 0 0 0 0 0 22 0 0 0 19 COG4102(Uncharacterized protein conserved in bacteria) 142 73 84 71 26 16 34 14 14 11 4 13 5 28 20 13 37 29 20 41 33 39 54 26 29 88 45 34 27 7 17 53 49 50 149 131 50 34 47 38 14 23 2 0 0 0 0 0 0 0 0 10 0 0 0 31 COG4584(Transposase and inactivated derivatives) 892 63 13 4 2 0 0 0 1 1 3 2 4 22 8 2 13 12 23 0 0 0 0 2 0 24 4 0 5 1 13 2 1 0 1 5 43 602 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG0425(Predicted redox protein, regulator of disulfide bond formation) 120 61 69 59 7 4 18 23 12 8 13 9 14 51 16 17 14 22 30 24 30 25 43 17 28 63 40 26 23 9 32 39 42 19 68 75 62 425 28 33 11 17 0 0 0 0 0 0 1 0 0 5 0 0 0 15 COG3807(Uncharacterized protein conserved in bacteria) 91 94 60 120 2 5 19 26 13 10 14 21 8 14 9 23 22 34 26 41 46 25 53 43 27 19 36 41 37 1 40 52 72 59 127 171 14 62 50 43 17 12 0 0 0 0 0 0 0 0 0 18 0 0 0 43 NOG14187(Uroporphyrinogen III synthase) 86 108 64 106 5 8 29 50 17 5 13 25 7 4 18 15 42 29 18 27 25 43 61 36 29 37 20 43 33 1 37 62 77 33 192 165 37 0 23 28 25 22 0 0 1 0 0 0 0 0 0 26 1 0 0 27 COG2375(Siderophore-interacting protein) 251 46 65 56 15 10 27 18 16 14 20 14 10 31 14 14 17 27 31 15 11 22 34 19 29 67 36 26 19 7 11 43 48 6 57 63 38 384 37 28 16 12 0 0 0 0 0 0 0 0 0 3 0 0 2 30 COG4230(Delta 1-pyrroline-5-carboxylate dehydrogenase) 278 113 97 64 10 5 8 18 11 11 19 16 13 55 20 30 23 23 40 19 22 23 57 13 25 5 19 18 15 11 9 51 57 20 116 114 87 128 19 27 13 6 0 0 0 0 0 0 0 0 0 13 3 0 0 13 NOG24538() 74 78 54 104 6 9 34 57 14 14 10 46 12 3 20 28 16 22 30 40 29 27 56 59 34 23 31 49 35 16 51 68 76 66 125 181 11 1 48 24 12 14 0 0 0 0 0 0 0 1 0 16 0 1 0 31 COG1914(Mn2+ and Fe2+ transporters of the NRAMP family) 578 46 38 24 18 3 23 22 17 6 13 18 12 36 7 11 20 15 9 25 19 17 24 20 17 93 9 19 30 23 24 32 16 23 65 82 30 136 34 44 11 12 0 0 1 0 0 0 0 0 2 16 0 0 0 15 COG1972(Nucleoside permease) 131 82 167 78 20 6 36 11 20 18 10 15 25 10 25 13 11 9 41 37 21 31 56 33 28 29 35 23 25 6 13 74 45 21 161 102 8 107 28 66 17 19 0 0 0 0 0 0 0 1 0 22 0 0 0 18 COG1726(Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA) 137 92 128 72 28 12 33 24 20 19 10 15 18 32 19 21 5 6 29 30 37 17 50 25 32 1 34 29 29 10 22 45 49 43 133 88 26 162 40 62 21 16 0 0 0 0 0 0 0 0 0 17 0 1 0 14 COG1420(Transcriptional regulator of heat shock gene) 107 48 87 46 7 7 23 15 8 14 9 3 11 39 10 13 57 63 36 28 16 20 38 16 13 155 28 26 18 10 25 47 28 25 79 115 30 303 45 42 8 9 0 0 0 0 0 0 0 0 0 9 0 0 0 16 COG1013(Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit) 120 68 169 80 4 3 25 4 13 3 3 3 13 45 25 17 18 8 32 47 24 76 61 32 28 43 39 47 24 5 28 33 34 36 41 109 46 211 22 19 22 15 1 0 0 0 2 0 0 0 0 11 0 0 0 41 COG4630(Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A) 160 78 77 90 4 12 14 19 10 8 7 11 8 19 7 5 17 10 19 41 26 24 45 26 38 10 41 31 23 5 21 65 47 48 123 253 47 52 50 68 15 12 2 0 0 0 0 0 0 0 0 16 0 0 0 46 COG1794(Aspartate racemase) 151 105 72 99 2 5 18 32 19 14 10 16 2 10 25 22 19 21 22 40 29 22 56 35 33 2 20 28 34 0 34 64 73 36 153 138 36 64 45 29 20 28 0 0 2 1 2 0 0 0 0 19 0 0 0 42 NOG18221() 78 90 75 103 2 16 33 44 19 16 4 26 14 33 29 25 17 15 15 50 53 43 65 45 49 2 35 41 32 2 38 63 62 54 129 135 24 0 36 39 15 13 0 0 0 1 0 1 0 0 0 28 0 0 0 35 COG1828(Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component) 82 85 59 92 4 8 30 37 11 22 14 14 7 20 7 15 31 38 25 36 45 37 72 40 44 36 32 45 38 15 39 43 44 28 108 125 13 152 36 34 11 16 0 0 0 0 0 2 0 0 0 25 0 0 1 26 COG2186(Transcriptional regulators) 899 21 10 13 4 12 1 7 3 5 4 9 4 20 12 5 37 23 24 19 8 11 18 10 5 40 18 13 10 4 4 16 13 4 18 23 42 301 16 13 4 2 0 0 0 0 0 0 0 0 0 3 0 0 0 15 COG0561(Predicted hydrolases of the HAD superfamily) 87 40 69 34 5 9 6 15 4 16 4 7 7 45 26 18 44 54 31 22 29 39 74 33 28 124 26 41 28 40 22 48 26 32 45 66 18 328 43 20 12 46 0 0 0 0 0 0 0 0 0 13 0 0 0 18 COG0035(Uracil phosphoribosyltransferase) 167 37 71 54 14 11 22 8 7 8 7 4 11 33 11 16 58 45 22 20 39 36 48 45 35 109 30 39 36 13 23 51 44 21 67 95 36 206 40 25 13 19 0 2 0 1 0 0 2 0 0 22 1 0 1 14 COG1587(Uroporphyrinogen-III synthase) 352 51 59 40 7 16 13 19 5 13 22 11 17 39 15 9 29 40 35 16 18 23 46 21 32 49 11 22 25 22 27 37 27 18 53 64 49 279 23 24 7 35 0 0 0 0 0 0 0 0 0 12 0 0 0 7 COG0062(Uncharacterized conserved protein) 182 58 129 103 3 5 10 19 4 7 11 2 7 34 14 11 5 4 18 28 36 57 67 44 49 80 22 20 35 19 41 35 20 15 36 95 38 274 27 31 11 13 0 0 0 0 0 0 0 0 0 14 0 0 0 5 COG3204(Uncharacterized protein conserved in bacteria) 455 30 49 34 8 7 9 11 5 6 27 2 2 20 8 7 7 8 20 18 54 37 81 34 37 24 26 48 18 10 15 43 47 23 71 127 6 123 40 41 19 31 0 0 2 0 0 0 0 0 0 18 0 0 0 29 NOG04035() 102 34 70 42 32 6 29 16 38 12 13 10 12 18 17 10 15 4 19 27 39 50 49 23 31 56 27 41 29 2 21 69 57 43 189 123 12 68 37 95 37 40 0 0 0 2 0 0 0 0 0 33 0 1 0 37 COG4221(Short-chain alcohol dehydrogenase of unknown specificity) 264 68 95 67 11 10 20 17 12 8 16 8 7 36 24 17 45 42 37 19 26 24 40 22 15 88 21 11 18 11 21 50 33 32 85 84 26 176 19 35 18 18 0 1 0 0 0 0 0 0 0 19 1 0 1 19 COG5410(Uncharacterized protein conserved in bacteria) 2 16 17 23 3 9 21 154 17 48 56 7 56 75 19 28 17 14 125 27 8 14 31 23 22 27 36 12 34 78 19 77 94 22 33 33 9 342 32 7 3 8 0 0 0 0 0 0 0 0 0 20 0 0 1 16 NOG06407() 19 48 113 39 51 6 61 28 35 19 22 19 29 22 23 13 14 33 14 31 24 48 64 25 24 21 24 56 28 11 21 81 44 38 154 105 11 108 21 105 25 15 0 0 0 0 0 0 0 0 0 11 0 0 0 32 COG0274(Deoxyribose-phosphate aldolase) 110 34 76 69 12 14 18 6 12 9 6 10 8 15 22 7 42 54 23 21 34 34 66 34 44 135 24 20 28 12 28 47 42 38 52 100 15 264 43 27 13 14 0 0 1 0 0 1 1 0 0 14 0 0 2 32 NOG19730() 88 100 59 132 1 4 37 27 10 6 12 19 21 26 33 31 23 20 10 54 39 35 41 33 28 1 30 48 24 5 38 49 42 60 98 201 29 61 19 47 18 23 0 0 0 0 0 0 0 0 0 16 0 0 0 33 COG1222(ATP-dependent 26S proteasome regulatory subunit) 132 71 104 74 12 10 29 22 10 6 8 12 25 25 17 16 23 34 25 42 37 43 52 31 45 56 17 33 45 16 33 57 31 33 105 108 43 82 39 35 22 17 0 0 0 0 0 0 0 0 0 13 0 0 1 39 COG1826(Sec-independent protein secretion pathway components) 222 69 54 83 5 3 28 23 10 7 4 15 7 41 8 13 29 20 14 24 34 27 40 24 38 49 25 19 35 12 37 37 34 21 110 111 41 217 32 32 14 25 0 0 1 0 0 0 2 0 0 10 0 0 0 24 COG4696(Uncharacterized protein conserved in bacteria) 70 81 103 99 10 3 38 51 18 21 28 24 16 18 20 17 18 19 16 25 37 26 64 33 39 19 36 32 33 3 26 59 55 49 178 133 27 19 14 57 24 14 0 0 0 0 0 0 0 0 0 24 0 0 0 34 NOG19828() 78 112 66 136 1 5 32 40 11 16 2 17 37 12 13 21 18 23 14 43 44 30 50 43 30 18 26 44 33 1 24 51 66 61 115 164 32 30 30 38 21 26 0 0 0 0 0 0 0 1 0 19 0 0 0 33 COG4942(Membrane-bound metallopeptidase) 128 46 84 55 20 7 27 31 18 15 13 29 13 55 17 26 20 15 26 18 18 19 50 22 39 14 39 42 21 5 14 53 46 25 103 69 48 278 29 53 25 22 0 0 0 0 0 0 0 0 0 16 0 0 2 12 COG1875(Predicted ATPase related to phosphate starvation-inducible protein PhoH) 167 22 33 23 3 5 8 20 9 16 7 5 6 20 1 11 61 70 20 10 32 30 45 25 27 218 14 18 35 29 18 26 19 14 31 38 36 435 23 24 8 20 0 0 0 0 0 0 0 0 0 14 0 0 0 30 COG2723(Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase) 78 60 95 50 13 9 24 17 7 5 4 18 8 33 15 14 34 57 27 37 47 38 59 29 44 61 46 56 33 14 25 40 47 36 61 67 18 238 39 21 21 20 0 0 0 0 0 0 0 0 0 16 0 0 0 43 COG1597(Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase) 113 102 140 94 2 4 21 8 6 6 7 9 12 19 8 13 53 87 21 35 49 65 70 34 44 131 21 25 21 4 13 32 37 24 36 74 11 148 17 23 26 11 0 0 0 0 0 0 0 0 0 14 0 0 1 32 COG2233(Xanthine/uracil permeases) 380 53 55 53 2 6 3 11 7 6 2 4 2 35 17 17 32 19 25 27 32 13 24 17 5 71 25 22 10 2 8 45 43 42 127 233 48 40 54 39 17 16 0 0 0 0 0 0 0 0 0 6 0 0 0 27 NOG11092(Alpha-1,2-Fucosyltransferase) 22 29 14 28 0 3 8 50 22 4 12 6 10 11 8 5 35 26 15 38 50 58 105 77 67 172 28 56 92 80 63 38 49 25 61 78 14 38 22 24 23 37 0 0 1 0 0 0 0 0 2 31 0 0 0 85 COG1076(DnaJ-domain-containing proteins 1) 199 80 86 96 15 7 29 23 17 12 25 10 10 30 18 12 12 22 27 27 24 33 47 39 31 20 39 34 25 6 39 52 35 38 100 159 37 66 18 48 14 19 0 0 0 0 0 0 0 0 0 17 0 0 0 24 COG5016(Pyruvate/oxaloacetate carboxyltransferase) 354 59 90 72 5 3 25 11 6 11 7 7 9 32 12 12 19 31 21 22 24 33 51 33 21 28 23 30 32 8 27 40 32 35 97 98 16 162 27 40 17 9 0 0 0 0 0 0 0 0 0 17 0 1 0 11 COG0155(Sulfite reductase, beta subunit (hemoprotein)) 350 35 39 53 20 20 4 13 10 13 24 15 9 48 18 9 22 27 38 21 63 27 58 37 59 41 11 20 23 41 37 46 22 10 34 42 44 149 72 25 7 13 0 0 0 0 2 1 0 0 0 30 0 0 0 15 COG1164(Oligoendopeptidase F) 75 65 93 78 7 19 21 11 18 11 14 7 19 56 32 10 26 24 24 25 30 33 60 24 25 105 39 37 24 7 24 70 54 25 116 86 28 151 37 28 13 16 0 1 0 0 0 0 0 0 0 14 0 0 0 35 COG4953(Membrane carboxypeptidase/penicillin-binding protein PbpC) 526 58 37 59 18 3 32 39 18 8 12 13 14 25 6 11 5 33 13 19 12 18 35 25 21 24 23 16 15 3 21 22 33 21 100 96 18 169 23 29 8 8 0 0 0 0 0 0 0 0 0 10 0 0 0 10 COG3409(Putative peptidoglycan-binding domain-containing protein) 47 28 49 36 14 15 24 9 4 11 16 14 14 15 14 21 26 55 30 22 37 36 84 43 41 118 46 39 44 22 37 51 41 24 50 108 20 238 38 30 19 6 0 0 0 0 2 0 0 0 0 23 0 1 0 46 COG0586(Uncharacterized membrane-associated protein) 423 54 60 32 5 3 16 7 3 11 6 3 4 26 16 4 67 98 16 11 28 16 35 23 35 193 19 7 21 10 27 31 20 18 39 29 34 182 23 14 5 13 0 0 1 0 0 0 1 0 0 6 0 0 0 9 COG0658(Predicted membrane metal-binding protein) 223 11 6 1 12 14 9 10 4 18 18 6 4 37 6 14 57 53 28 6 5 1 7 1 5 190 7 2 0 4 0 9 3 2 12 5 77 794 17 10 0 0 0 0 2 0 0 0 0 0 0 2 0 0 0 5 COG1206(NAD(FAD)-utilizing enzyme possibly involved in translation) 62 58 47 61 10 16 23 26 11 10 16 9 5 47 18 12 8 4 10 30 57 35 74 43 59 24 24 45 27 19 39 76 52 30 113 99 22 217 63 37 9 13 0 2 0 0 0 0 0 0 0 18 0 2 0 12 COG3547(Transposase and inactivated derivatives) 597 104 13 6 3 0 1 1 2 2 24 1 3 12 5 5 1 2 15 4 1 3 6 2 1 20 1 0 4 4 1 5 0 0 10 10 111 700 8 2 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1946(Acyl-CoA thioesterase) 94 112 121 66 9 9 22 22 14 8 19 10 10 25 19 13 11 36 40 34 36 16 54 26 36 82 34 20 16 8 22 48 44 38 99 98 6 202 20 31 11 19 0 1 0 0 0 0 1 0 0 11 0 0 0 18 COG2169(Adenosine deaminase) 900 30 13 6 1 4 2 7 6 5 10 1 8 26 8 3 6 3 10 8 7 3 14 7 8 29 12 0 5 3 2 22 11 16 33 22 65 325 21 11 2 2 0 0 0 0 0 0 0 0 0 2 1 1 0 9 NOG28122() 92 98 86 123 1 4 27 31 8 18 6 18 13 23 24 23 25 16 23 37 34 30 40 33 30 0 39 28 36 0 25 55 52 45 120 200 22 8 41 47 30 24 0 0 0 0 0 1 0 0 0 16 1 0 0 28 COG0817(Holliday junction resolvasome, endonuclease subunit) 112 39 72 51 16 16 8 22 16 12 9 17 15 57 13 18 47 44 22 21 21 24 75 23 30 105 21 18 22 8 14 43 34 18 50 64 49 319 26 34 9 21 0 0 0 2 0 0 0 0 0 9 0 0 0 13 COG4448(L-asparaginase II) 131 42 59 50 1 12 3 9 7 6 2 14 18 13 14 19 62 48 22 18 41 39 78 32 25 138 30 30 24 11 20 44 44 20 54 92 8 228 40 20 17 29 0 0 0 0 0 0 0 0 0 21 0 0 0 44 COG0804(Urea amidohydrolase (urease) alpha subunit) 178 78 74 121 11 35 9 9 4 16 12 9 20 34 14 4 12 8 22 25 69 26 83 55 75 9 35 24 43 26 42 17 23 29 75 44 13 158 47 20 5 10 0 0 0 1 0 0 0 0 0 15 0 0 0 37 COG0779(Uncharacterized protein conserved in bacteria) 110 69 82 61 6 10 22 33 8 19 15 7 13 54 22 14 24 45 19 22 24 37 66 30 44 92 27 26 31 10 16 46 40 29 70 59 34 199 36 18 21 6 2 0 0 0 0 0 0 0 0 13 1 0 0 37 COG1428(Deoxynucleoside kinases) 83 79 126 63 29 12 25 29 23 11 25 34 7 32 26 25 20 33 25 34 18 20 64 32 45 20 23 20 24 5 21 65 51 45 113 136 18 66 24 43 29 10 0 0 0 0 0 0 2 0 0 10 0 0 0 23 COG2035(Predicted membrane protein) 65 52 66 42 26 3 22 25 21 9 14 8 7 30 17 26 6 25 29 44 30 36 36 22 19 1 32 27 28 9 11 73 49 49 102 113 39 266 35 53 16 27 0 0 0 0 0 0 0 0 0 23 0 0 0 29 COG3030(Protein affecting phage T7 exclusion by the F plasmid) 116 85 74 102 5 12 18 38 11 19 23 22 4 13 33 15 29 25 18 27 17 25 48 32 30 5 33 25 24 0 26 45 49 54 114 157 39 107 21 42 19 16 2 0 0 1 0 0 0 0 2 6 0 0 0 33 COG1523(Type II secretory pathway, pullulanase PulA and related glycosidases) 442 48 21 31 5 11 5 3 0 7 3 4 12 8 0 3 39 57 19 11 40 31 60 25 49 153 11 14 24 25 42 34 11 2 18 9 6 312 42 3 2 0 0 0 0 0 1 0 0 0 0 11 1 0 1 3 COG1678(Putative transcriptional regulator) 117 65 126 67 8 14 27 27 14 9 27 9 5 38 15 9 10 12 19 27 29 20 59 22 25 36 28 22 25 11 23 63 59 22 93 139 19 182 22 45 17 14 0 0 0 0 0 0 0 0 0 19 0 0 0 20 COG1298(Flagellar biosynthesis pathway, component FlhA) 261 48 46 33 13 18 9 12 13 15 18 13 13 48 21 12 23 22 22 27 18 37 37 29 31 23 33 27 22 6 21 34 32 29 81 52 35 296 18 38 10 22 0 0 0 0 0 0 0 0 0 18 0 0 0 20 COG5301(Phage-related tail fibre protein) 119 19 11 22 6 13 15 69 12 33 121 21 24 16 8 20 25 42 32 35 38 25 80 42 30 163 13 22 18 60 14 22 36 20 32 45 15 175 34 12 8 14 0 0 0 0 0 0 0 0 0 8 0 1 0 63 COG2918(Gamma-glutamylcysteine synthetase) 158 101 109 68 4 2 21 30 12 16 19 22 14 53 12 20 8 12 27 30 14 24 59 27 15 1 31 21 24 4 12 34 27 27 120 95 31 229 23 36 14 25 0 0 0 0 0 0 0 0 0 9 0 0 0 13 COG1484(DNA replication protein) 805 46 23 10 2 0 1 0 0 2 0 1 0 9 6 3 13 7 9 3 1 3 10 2 6 18 11 4 5 2 2 2 3 0 2 5 51 580 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG0348(Polyferredoxin) 469 33 13 17 7 3 11 18 6 11 14 12 9 14 17 9 27 42 8 22 10 8 17 3 21 51 20 8 6 2 10 13 19 9 36 57 77 466 14 18 4 8 0 0 0 0 0 0 0 2 0 7 0 0 0 0 NOG22321(Terminase, large subunit) 14 28 19 27 3 1 6 75 20 17 47 7 20 18 17 18 12 24 43 40 26 28 86 59 40 169 42 36 40 69 48 67 57 19 19 39 5 121 42 19 28 16 0 0 0 0 0 0 0 0 0 20 0 0 0 95 COG0610(Type I site-specific restriction-modification system, R (restriction) subunit and related helicases) 320 49 46 30 7 11 6 20 5 9 14 8 6 26 23 12 24 33 25 26 31 24 47 13 23 56 20 21 6 12 9 26 18 28 41 47 71 339 22 22 20 12 0 0 0 0 0 0 0 0 0 19 0 0 0 18 COG0767(ABC-type transport system involved in resistance to organic solvents, permease component) 221 29 34 35 21 15 28 23 11 8 8 12 9 28 14 14 27 20 18 20 14 25 39 26 23 50 29 22 32 19 32 57 28 29 88 52 46 308 20 47 17 12 0 0 0 2 0 0 0 0 0 10 0 0 0 21 COG3825(Uncharacterized protein conserved in bacteria) 129 115 109 81 9 9 31 38 12 10 9 8 13 48 18 12 16 8 32 21 37 37 88 25 46 4 26 32 30 16 21 70 41 37 110 76 14 62 32 50 15 14 0 0 0 0 0 0 0 0 0 22 0 0 0 10 COG3264(Small-conductance mechanosensitive channel) 310 28 43 29 14 3 6 26 17 9 18 9 8 44 20 12 23 17 27 22 21 18 24 13 16 30 21 10 7 5 13 27 22 21 54 42 23 469 30 34 13 21 0 0 0 0 0 0 0 0 0 9 0 0 0 10 COG2825(Outer membrane protein) 119 86 101 80 9 8 37 37 4 14 14 21 6 21 17 21 23 17 17 33 40 26 64 23 17 22 24 46 20 7 34 58 40 35 124 129 47 55 38 33 13 20 0 0 0 0 0 2 0 0 0 13 0 0 0 18 COG2127(Uncharacterized conserved protein) 115 45 48 57 9 9 12 9 11 11 17 18 8 39 21 8 32 42 26 13 36 29 63 32 41 123 32 26 26 21 14 44 40 23 80 78 22 192 55 34 19 16 1 0 0 0 1 0 0 0 0 15 0 0 0 17 NOG06100(Secreted protein) 83 221 285 124 41 34 72 4 0 4 14 1 4 19 8 8 2 18 22 25 21 71 160 46 41 52 5 13 6 2 3 12 2 4 11 10 7 147 4 7 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 13 COG3786(Uncharacterized protein conserved in bacteria) 79 94 46 106 5 6 28 38 12 10 9 20 10 20 15 12 19 26 18 23 28 26 43 36 37 17 36 33 23 1 19 46 54 44 111 179 30 83 35 50 19 32 0 0 0 0 0 0 1 0 0 16 0 0 1 32 NOG10303(Protein involved in DNA modification) 6 23 50 36 8 8 11 170 29 39 121 12 45 29 22 38 14 8 121 18 14 42 107 33 31 7 53 28 15 81 8 34 82 14 31 52 14 47 13 26 11 26 0 0 0 0 0 0 1 0 0 16 0 0 0 33 NOG09860() 132 65 116 42 4 12 2 33 10 18 23 12 11 56 16 15 8 21 29 23 19 39 33 24 14 33 28 23 15 7 8 48 49 25 113 93 13 269 22 49 15 17 0 2 2 0 0 0 0 0 0 7 0 0 0 9 COG2015(Alkyl sulfatase and related hydrolases) 78 69 107 83 7 5 32 25 13 7 19 19 10 43 8 14 30 31 33 34 24 19 52 41 31 123 37 23 35 7 16 45 27 26 113 106 11 75 22 43 12 20 0 0 0 0 2 0 0 0 0 20 0 0 0 24 COG0297(Glycogen synthase) 137 45 83 46 15 9 6 13 6 11 11 17 11 13 9 5 18 25 30 20 35 17 88 40 38 28 28 36 25 19 19 36 15 25 64 51 38 361 33 44 13 17 0 0 0 0 0 0 0 0 0 12 0 0 2 7 COG0775(Nucleoside phosphorylase) 267 57 99 46 4 4 16 33 19 14 7 28 17 36 8 15 22 20 14 11 20 22 46 34 21 43 24 10 16 13 11 43 39 24 91 93 28 166 36 40 16 4 0 0 0 0 0 0 0 0 0 12 0 0 0 23 COG5307(SEC7 domain proteins) 24 73 81 111 78 139 19 30 12 15 0 17 27 38 14 11 31 16 12 23 15 47 66 16 68 63 50 15 1 123 15 34 7 0 7 89 86 95 4 9 3 6 0 0 0 0 0 0 0 0 0 9 0 0 0 12 COG2805(Tfp pilus assembly protein, pilus retraction ATPase PilT) 164 58 68 62 10 9 7 24 12 28 9 22 3 19 19 15 24 24 20 29 29 22 43 34 43 46 25 18 32 10 15 27 18 17 48 105 103 220 43 9 8 15 0 0 0 0 0 0 0 0 0 14 0 0 0 25 COG1575(1,4-dihydroxy-2-naphthoate octaprenyltransferase) 91 26 76 51 19 11 25 6 5 4 6 16 12 17 12 12 41 59 17 26 24 39 64 29 34 96 33 26 26 23 28 44 41 34 76 94 14 186 44 35 20 11 0 0 0 0 0 0 0 2 0 12 0 0 0 28 COG0846(NAD-dependent protein deacetylases, SIR2 family) 177 63 86 64 20 20 17 10 5 3 7 5 1 31 12 15 13 17 30 20 31 23 45 19 29 34 30 35 21 15 22 35 40 20 59 89 40 233 25 29 25 27 0 0 0 0 0 0 0 0 0 24 0 1 0 26 COG1858(Cytochrome c peroxidase) 325 49 56 48 9 1 11 16 29 10 20 12 24 37 7 13 19 17 35 13 13 11 32 17 14 28 23 26 19 3 8 39 22 28 37 69 39 316 22 33 3 10 0 0 0 0 0 0 0 0 0 15 0 0 2 11 NOG13487() 61 78 60 77 5 2 31 29 11 10 13 13 2 13 11 20 13 17 25 41 32 28 50 25 29 13 21 38 28 0 49 48 72 42 170 172 25 46 32 44 27 3 0 1 1 0 0 0 0 0 0 22 0 0 0 39 COG5275(BRCT domain type II) 192 41 65 54 14 2 32 16 14 17 1 12 12 34 17 22 29 28 42 20 26 15 34 30 26 102 29 27 23 0 25 45 42 27 69 114 34 89 42 29 15 10 0 0 0 0 0 0 0 0 0 17 0 2 0 52 COG1660(Predicted P-loop-containing kinase) 207 23 21 23 3 6 21 19 5 2 18 13 8 43 4 19 61 76 25 15 15 12 27 32 19 170 21 11 27 3 16 27 32 19 38 73 25 311 23 26 13 8 0 0 0 0 0 0 0 0 0 13 0 0 0 15 COG3038(Cytochrome B561) 342 69 35 42 2 5 36 20 14 4 29 15 9 20 18 9 34 47 20 27 37 26 38 27 32 19 35 35 22 2 16 45 43 44 94 41 21 112 28 13 13 9 0 0 1 0 0 0 0 0 0 6 0 0 0 26 COG1576(Uncharacterized conserved protein) 74 71 109 71 25 6 20 29 10 12 12 11 12 26 17 11 17 15 19 17 40 29 63 39 36 32 16 17 19 15 22 59 44 36 78 94 45 187 30 36 11 13 0 2 0 1 0 0 0 0 2 15 0 0 0 15 COG0603(Predicted PP-loop superfamily ATPase) 165 56 79 66 4 11 10 19 7 14 21 10 18 28 26 12 26 25 20 14 39 33 63 35 33 80 32 13 30 15 32 44 40 23 21 48 32 237 40 16 13 5 0 0 2 0 0 0 0 0 0 6 0 0 0 15 COG0780(Enzyme related to GTP cyclohydrolase I) 222 82 118 76 8 14 12 19 5 19 26 8 10 42 17 10 17 34 23 20 34 25 72 28 40 39 18 25 29 26 24 28 21 12 57 61 24 145 27 19 13 13 0 0 0 0 0 0 0 0 0 8 0 0 0 5 COG0391(Uncharacterized conserved protein) 86 49 52 56 3 10 11 3 4 2 0 9 5 21 16 11 46 49 15 13 50 28 51 33 32 159 14 29 28 26 56 45 26 25 38 64 38 264 34 14 15 15 0 0 0 0 0 0 0 0 0 11 0 0 0 18 COG1925(Phosphotransferase system, HPr-related proteins) 433 20 18 21 4 3 8 10 11 4 18 7 10 24 17 9 13 16 17 7 14 10 20 11 13 23 21 32 7 2 5 26 25 16 71 44 17 465 12 17 7 7 0 0 0 1 0 0 0 0 0 8 0 0 0 23 COG2059(Chromate transport protein ChrA) 634 12 12 36 4 9 9 12 11 2 10 6 2 23 8 8 24 15 19 9 37 19 30 27 25 71 3 6 3 6 14 15 8 4 26 14 12 325 7 7 4 6 0 0 0 0 0 0 0 0 0 7 0 0 0 11 COG2027(D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)) 229 30 86 33 9 9 9 2 5 5 16 4 10 47 4 5 49 58 17 10 17 18 46 20 28 163 9 19 27 17 22 23 13 4 25 34 25 336 23 24 2 3 0 2 0 0 0 0 0 0 0 10 0 0 0 4 COG0255(Ribosomal protein L29) 68 45 45 69 5 10 18 38 18 10 11 17 15 33 15 19 33 36 21 32 22 17 36 25 28 90 22 26 19 8 28 40 43 29 103 72 29 231 29 38 11 10 0 0 0 0 1 0 0 0 0 9 0 0 0 26 COG1110(Reverse gyrase) 77 51 78 67 6 12 43 15 9 2 4 14 3 17 15 16 47 23 20 28 50 36 44 33 47 100 18 26 23 12 26 33 22 7 35 87 16 283 18 17 8 9 0 0 0 0 0 0 2 0 0 26 0 0 0 23 NOG09628(2Og-Fe(Ii) oxygenase family) 54 32 44 34 4 3 8 57 19 7 18 5 8 8 9 11 3 14 29 45 34 44 94 62 50 77 15 58 63 104 27 43 27 48 43 84 5 40 64 17 23 15 0 0 0 0 0 0 0 0 0 11 0 0 0 88 NOG20048() 91 93 47 113 4 4 31 28 7 10 3 24 10 7 12 30 30 22 10 31 40 22 45 34 40 27 21 33 26 0 33 56 50 40 133 167 27 7 27 41 16 10 0 0 0 2 0 0 0 0 0 17 0 0 0 27 COG0246(Mannitol-1-phosphate/altronate dehydrogenases) 192 35 42 34 3 14 25 32 35 18 13 19 37 59 16 20 11 30 28 45 21 23 52 16 15 14 20 28 12 4 9 57 38 32 66 99 17 159 18 49 21 22 0 0 0 0 0 2 0 0 0 21 0 0 0 23 COG0333(Ribosomal protein L32) 48 73 69 75 9 10 32 34 9 19 11 18 4 21 18 15 19 24 23 35 22 13 38 39 33 29 31 31 18 4 20 61 44 45 134 114 31 107 38 34 18 23 2 0 0 0 0 0 0 1 0 14 0 0 0 35 COG4214(ABC-type xylose transport system, permease component) 446 20 26 33 1 3 8 2 6 6 12 3 7 29 6 5 20 34 10 9 13 11 23 17 10 134 26 18 9 0 9 33 18 21 46 37 46 291 20 33 16 12 0 0 0 0 0 0 0 0 0 11 0 0 0 3 COG2020(Putative protein-S-isoprenylcysteine methyltransferase) 248 72 115 55 8 11 16 14 4 6 10 4 7 14 17 5 8 15 10 11 33 23 64 33 30 18 23 29 30 15 23 43 23 20 80 59 9 226 32 30 12 8 0 0 0 0 0 0 0 0 0 13 0 1 0 14 COG3328(Transposase and inactivated derivatives) 440 11 2 4 7 2 0 0 1 0 3 5 2 28 2 2 10 3 11 2 1 3 2 4 2 18 0 0 0 8 1 2 1 0 6 3 101 844 0 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG4253(Uncharacterized protein conserved in bacteria) 1488 0 8 4 0 0 1 0 0 0 0 0 0 1 0 0 3 0 0 0 0 0 0 1 4 0 1 0 0 1 4 0 2 0 0 0 2 2 2 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4133(ABC-type transport system involved in cytochrome c biogenesis, ATPase component) 107 98 105 59 8 11 17 33 8 13 16 11 8 52 20 11 10 19 31 16 24 21 39 16 29 22 31 15 20 3 14 57 35 33 107 103 22 158 16 39 21 12 0 0 0 0 0 0 1 0 0 16 0 0 0 22 NOG18195() 9 23 77 19 15 3 10 93 54 27 29 38 97 37 25 31 10 19 56 54 29 13 38 8 30 46 25 30 19 13 11 38 32 28 39 81 21 201 17 21 20 7 0 0 0 0 0 0 0 0 0 13 0 0 0 16 COG1092(Predicted SAM-dependent methyltransferases) 282 13 19 17 9 12 8 8 14 16 17 6 5 49 12 7 30 33 29 10 12 10 11 10 19 73 12 11 13 6 7 37 29 27 39 35 81 386 26 25 14 8 0 2 0 0 0 0 0 0 0 10 0 0 0 20 COG2259(Predicted membrane protein) 423 61 33 63 3 3 21 17 6 10 4 4 7 14 10 7 23 27 8 22 16 22 41 23 12 55 19 22 26 11 25 53 34 31 62 106 28 47 29 24 19 17 0 0 2 0 0 0 0 0 0 12 0 0 0 16 COG3448(CBS-domain-containing membrane protein) 200 96 69 102 0 5 18 31 15 18 6 27 6 9 22 23 19 27 12 30 26 21 37 21 30 11 26 18 32 3 22 51 36 36 103 135 29 1 25 29 19 23 0 0 0 0 0 0 1 0 0 15 0 0 0 33 COG2264(Ribosomal protein L11 methylase) 134 37 40 35 11 16 11 20 19 16 24 10 18 50 5 13 14 19 38 12 25 37 55 30 43 58 34 12 17 21 17 36 29 15 62 68 38 255 40 29 9 10 0 0 0 0 0 0 0 0 0 13 0 0 0 18 COG4566(Response regulator) 602 26 30 12 1 0 8 15 8 8 24 11 2 28 7 4 32 25 7 6 8 4 12 6 9 73 15 22 5 10 6 12 14 9 41 36 71 243 17 17 6 6 0 0 1 0 0 0 0 0 0 2 0 0 0 11 COG0007(Uroporphyrinogen-III methylase) 333 57 38 53 5 13 4 20 3 18 21 12 23 41 15 4 25 26 33 19 36 15 41 31 34 28 16 21 20 19 29 30 11 17 38 49 30 197 35 14 2 15 0 0 0 0 0 0 0 0 0 7 0 0 0 13 COG2816(NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding) 54 53 92 45 3 12 20 28 12 21 2 7 15 34 10 7 38 36 26 19 25 22 51 17 24 88 22 12 25 6 18 36 33 27 82 68 27 256 36 29 9 23 0 0 0 0 0 0 0 0 0 20 0 0 0 15 COG0362(6-phosphogluconate dehydrogenase) 166 37 22 43 6 11 16 12 5 8 7 11 3 36 21 26 6 21 28 37 45 22 69 39 57 10 31 47 28 35 16 44 33 20 64 74 53 146 46 24 23 12 1 0 0 0 0 0 0 0 0 12 0 0 0 30 COG2273(Beta-glucanase/Beta-glucan synthetase) 14 57 132 43 32 8 32 34 15 11 43 14 14 33 10 15 23 18 30 34 25 30 57 24 28 21 51 24 25 5 15 67 36 26 136 76 22 66 36 53 22 15 0 0 0 0 0 0 0 0 0 8 0 0 0 21 COG1757(Na+/H+ antiporter) 268 74 111 57 24 3 14 24 19 10 21 10 13 49 16 16 3 4 40 20 8 25 40 21 13 5 25 18 10 6 11 37 36 27 83 90 18 121 15 48 11 4 0 0 0 0 0 0 0 0 0 10 0 0 0 22 COG0602(Organic radical activating enzymes) 128 44 84 57 14 6 15 24 10 15 32 16 8 29 20 13 26 20 29 23 35 35 58 39 28 71 19 29 25 17 23 29 50 35 27 67 33 158 29 25 15 14 0 0 1 0 0 0 0 0 0 10 0 0 0 15 COG5362(Phage-related terminase) 1 11 14 21 2 8 18 127 15 33 48 8 52 65 15 27 11 13 121 20 11 17 30 17 19 24 35 19 27 63 12 63 85 11 27 23 9 304 19 5 3 10 0 0 0 0 0 0 0 0 0 19 0 0 0 16 COG3325(Chitinase) 249 47 98 18 10 6 11 13 14 0 9 8 3 22 12 18 12 23 19 12 33 39 51 22 18 29 21 9 9 6 9 30 31 27 77 49 45 272 15 39 13 12 0 0 0 0 2 0 0 0 0 16 0 0 0 16 NOG18147() 2 19 21 14 9 8 13 93 15 12 44 14 23 16 4 19 29 22 28 36 19 28 63 34 16 216 47 18 33 67 14 63 72 40 39 59 6 42 34 32 26 16 0 0 0 0 0 0 0 0 2 6 0 0 0 60 NOG18609(ETC complex I subunit) 67 76 43 84 3 6 29 31 10 18 7 15 11 49 20 15 18 11 19 33 35 24 44 29 27 19 28 31 32 1 16 59 55 49 96 134 13 54 37 55 8 15 0 0 0 0 0 2 0 0 0 23 0 1 0 41 COG1640(4-alpha-glucanotransferase) 264 25 31 36 4 9 10 10 1 0 3 3 7 7 17 13 14 11 7 30 40 32 75 36 59 35 33 24 33 24 45 30 25 22 35 31 20 245 36 16 13 18 0 0 0 0 0 0 0 0 0 19 0 0 2 39 COG0043(3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases) 192 64 150 78 2 5 2 14 8 8 5 5 8 50 24 8 19 8 14 37 32 32 49 16 16 74 19 12 13 12 7 40 32 13 13 68 41 177 33 23 18 16 0 0 0 0 0 0 0 0 0 5 0 0 3 23 COG3217(Uncharacterized Fe-S protein) 282 41 34 47 5 7 9 35 13 8 12 31 13 32 8 13 30 23 29 17 19 14 28 25 31 4 21 29 12 8 14 39 35 26 79 103 37 166 19 34 14 14 0 0 0 0 0 0 0 0 0 7 0 0 0 21 COG1135(ABC-type metal ion transport system, ATPase component) 479 14 23 27 3 3 9 3 1 3 15 4 2 25 2 5 3 10 5 19 19 34 23 22 20 83 17 17 16 8 14 20 23 8 18 41 31 335 31 17 12 10 0 0 0 0 0 0 0 0 0 3 0 0 0 9 COG5276(Uncharacterized conserved protein) 13 45 190 56 23 4 23 21 16 5 18 20 15 29 16 11 33 6 15 13 18 44 37 24 26 7 25 39 26 11 18 54 35 10 83 115 32 179 16 49 14 16 2 2 0 0 2 0 0 0 0 16 0 0 0 14 COG4976(Predicted methyltransferase (contains TPR repeat)) 178 65 72 55 5 8 25 34 14 14 6 20 11 41 28 10 12 8 22 28 18 27 49 27 32 24 31 29 23 7 32 30 45 33 65 146 31 34 43 49 8 15 0 0 2 1 0 0 0 0 0 8 0 0 0 20 COG0631(Serine/threonine protein phosphatase) 46 21 48 27 23 28 17 4 2 0 6 17 9 25 16 12 40 52 37 13 22 16 14 13 15 143 18 28 14 45 12 20 24 17 23 61 44 430 22 8 11 6 0 0 0 0 0 0 0 0 0 7 0 0 0 29 COG5267(Uncharacterized protein conserved in bacteria) 138 56 66 52 17 13 23 12 12 3 5 2 11 23 23 14 36 43 16 21 30 27 57 22 27 73 35 33 17 1 15 37 46 18 125 86 47 29 54 54 9 13 0 0 0 0 0 0 0 0 2 12 0 0 0 25 COG1561(Uncharacterized stress-induced protein) 125 73 103 51 25 11 20 31 26 12 23 7 21 44 6 11 15 20 24 24 22 15 39 24 20 26 18 22 18 11 6 38 34 34 107 89 23 106 35 59 10 15 0 0 0 0 0 0 1 0 0 12 0 0 0 22 COG2957(Peptidylarginine deiminase and related enzymes) 284 104 100 127 9 3 37 23 8 8 3 3 7 11 11 3 17 38 9 9 21 37 51 34 44 93 18 13 21 5 17 14 33 13 52 45 12 76 19 22 6 0 0 0 0 0 0 0 0 0 0 10 0 0 0 8 COG0116(Predicted N6-adenine-specific DNA methylase) 217 17 15 29 17 12 7 6 9 13 10 15 8 31 6 7 27 19 23 6 32 12 35 33 25 46 25 22 22 19 18 45 24 27 46 45 76 295 47 41 18 4 0 0 0 0 0 0 0 0 0 14 0 0 0 12 NOG11191() 63 66 46 87 5 8 22 31 13 13 14 18 7 6 32 18 37 36 14 34 31 18 57 28 37 38 46 30 30 7 29 56 50 36 114 130 14 22 29 34 21 8 0 0 0 0 0 0 0 0 0 11 0 0 0 31 COG3501(Uncharacterized protein conserved in bacteria) 1165 16 15 8 19 3 4 2 1 1 0 4 4 21 0 0 10 5 7 2 12 4 7 6 27 8 4 5 0 9 1 6 3 2 6 11 11 28 19 4 7 0 0 0 0 0 0 0 0 0 0 2 0 0 1 5 NOG08489() 5 7 11 16 3 4 4 57 8 21 32 21 15 4 7 9 3 35 17 31 36 54 178 88 70 167 24 51 78 132 24 23 35 14 17 14 4 8 18 15 19 3 0 0 0 0 0 0 0 0 0 12 2 0 1 78 COG1446(Asparaginase) 128 77 134 42 22 7 29 8 27 3 15 22 9 25 20 8 4 7 20 31 38 30 44 26 11 23 21 25 22 12 22 57 33 25 118 112 15 38 29 51 26 16 0 0 0 0 0 1 0 0 0 21 0 0 0 20 COG1589(Cell division septal protein) 111 53 80 65 5 10 10 14 4 5 5 4 1 23 15 6 21 24 23 23 29 23 60 24 41 47 12 27 26 12 27 42 21 22 49 68 19 314 27 34 9 7 0 0 0 0 0 1 0 0 0 9 0 1 0 21 NOG07590() 38 137 175 77 7 6 19 27 9 30 3 6 19 29 12 14 1 4 17 14 29 42 43 20 22 15 27 29 41 15 11 50 48 16 105 72 6 100 26 33 21 15 0 0 0 0 4 0 0 0 0 30 0 0 0 9 COG2307(Uncharacterized protein conserved in bacteria) 233 78 44 59 9 16 21 10 1 3 1 2 7 9 9 4 27 15 16 19 36 36 69 40 33 19 9 11 26 17 44 1 0 5 16 3 24 454 27 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 12 COG2335(Secreted and surface protein containing fasciclin-like repeats) 104 15 33 22 11 7 15 20 29 1 13 36 19 26 24 15 2 17 22 20 20 57 49 23 28 14 25 38 26 19 14 81 76 44 79 110 4 124 10 48 30 32 0 0 2 0 0 0 0 0 0 15 1 0 0 52 COG0338(Site-specific DNA methylase) 51 20 40 27 4 0 5 52 24 7 5 13 11 13 17 10 18 28 21 46 29 29 92 42 70 143 15 51 33 47 42 40 28 38 33 49 41 42 39 19 35 24 0 0 0 0 0 2 0 0 0 18 0 0 0 58 COG1949(Oligoribonuclease (3->5 exoribonuclease)) 94 66 97 51 3 5 10 17 8 7 11 16 8 26 15 12 50 52 23 18 10 15 45 22 13 120 13 17 18 9 19 38 31 19 62 78 31 230 20 21 16 9 0 0 0 0 0 1 0 0 0 4 0 1 0 18 COG0390(ABC-type uncharacterized transport system, permease component) 208 38 75 33 21 5 9 5 2 7 8 8 12 22 6 8 21 31 22 18 12 23 27 11 11 68 27 14 15 15 19 11 11 2 30 42 10 495 18 10 4 10 0 0 0 0 0 0 0 0 0 7 0 0 0 13 COG0418(Dihydroorotase) 160 37 35 56 6 16 14 11 10 9 12 7 8 41 22 18 19 23 16 20 26 21 66 32 38 12 23 19 27 16 41 55 25 36 83 80 16 189 45 25 8 10 0 2 0 0 2 0 0 0 0 11 0 0 0 15 COG1266(Predicted metal-dependent membrane protease) 72 23 72 37 10 14 7 6 15 11 15 7 10 16 14 6 7 21 18 18 46 22 75 24 37 60 26 23 19 32 18 39 37 19 70 41 7 322 60 42 21 13 0 0 0 1 0 0 0 0 0 4 0 0 0 6 COG1434(Uncharacterized conserved protein) 168 34 40 39 5 12 8 33 5 4 2 11 10 21 22 16 34 47 20 17 17 13 25 23 23 127 20 12 15 5 23 39 25 19 43 67 28 268 29 35 9 16 0 0 0 0 0 0 0 0 0 6 1 0 0 23 NOG18999() 60 100 47 102 4 2 19 45 5 13 4 15 5 2 15 18 34 31 14 42 30 21 36 23 35 27 27 29 25 7 20 39 54 46 118 149 15 57 30 24 16 18 0 0 0 0 0 0 0 0 0 13 0 0 0 22 COG3670(Lignostilbene-alpha,beta-dioxygenase and related enzymes) 134 52 105 54 15 12 18 12 5 10 8 9 5 32 19 17 9 15 37 32 41 28 60 26 52 71 30 21 37 18 22 52 35 27 64 86 8 98 38 14 5 6 0 0 0 0 0 0 0 0 0 10 0 0 0 9 COG1393(Arsenate reductase and related proteins, glutaredoxin family) 261 34 71 48 9 9 2 18 12 15 14 15 8 47 13 13 21 17 18 31 22 25 37 30 18 15 34 12 27 14 20 45 26 20 68 63 42 144 25 31 16 19 1 0 1 0 0 0 0 0 0 11 0 0 0 11 COG0720(6-pyruvoyl-tetrahydropterin synthase) 123 36 85 48 23 4 19 13 23 8 15 14 12 37 18 6 16 15 30 16 35 27 66 29 33 70 21 35 37 24 24 43 38 30 46 57 16 113 37 50 12 14 0 1 0 0 0 0 0 0 0 12 0 0 0 17 COG3293(Transposase and inactivated derivatives) 228 68 31 38 1 10 14 20 10 8 8 8 20 29 10 10 10 9 38 8 13 6 25 14 14 10 7 12 12 5 20 14 15 17 50 64 72 426 19 20 13 8 0 0 2 0 0 0 0 0 0 5 0 0 0 2 COG2866(Predicted carboxypeptidase) 179 37 110 19 16 11 7 7 14 3 8 5 5 21 7 8 29 25 17 23 33 51 53 23 19 89 16 17 25 27 14 37 52 32 33 70 20 115 8 43 41 20 0 0 0 0 0 0 0 0 0 16 0 0 0 37 COG2065(Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase) 52 21 41 40 11 4 18 15 13 0 5 7 4 21 12 7 38 50 17 26 29 23 60 32 28 110 19 26 32 6 25 43 29 28 68 87 25 256 28 23 12 8 0 0 1 0 0 0 0 0 0 15 0 2 0 25 COG4820(Ethanolamine utilization protein, possible chaperonin) 113 51 78 72 8 7 40 27 14 13 1 12 15 13 8 25 13 24 22 27 42 42 45 21 45 37 27 25 19 1 37 46 32 20 72 98 18 107 41 18 14 10 0 1 0 0 0 0 0 0 0 10 0 0 0 26 COG1951(Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain) 138 32 20 27 12 6 5 24 8 14 15 5 12 54 20 19 74 101 30 14 14 17 22 13 17 158 23 14 10 3 11 28 16 11 24 48 32 289 4 27 5 7 0 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG13036() 57 69 90 98 2 4 9 23 17 9 8 9 3 35 27 16 11 9 21 40 12 16 59 29 17 6 32 25 20 1 8 41 53 41 120 204 22 20 41 38 9 16 0 0 0 0 0 0 1 0 0 9 0 1 1 33 NOG05999(Iron ion binding protein) 151 90 50 93 0 4 23 34 13 11 7 24 11 7 19 23 28 24 23 33 26 28 33 34 23 16 41 29 28 0 27 39 42 30 108 129 12 0 23 18 23 11 0 0 0 0 0 0 0 0 0 19 2 1 0 21 NOG06408() 118 54 127 51 25 1 17 21 19 19 10 10 5 15 14 13 10 7 21 8 30 45 41 36 26 11 17 22 22 12 19 39 28 28 127 76 13 108 24 52 27 5 0 1 0 0 2 0 0 2 0 23 0 0 0 29 COG1321(Mn-dependent transcriptional regulator) 32 35 53 33 6 13 17 13 9 1 7 14 13 27 27 8 24 16 22 31 21 36 58 31 26 60 33 33 28 11 29 50 42 25 54 85 30 210 26 45 16 19 0 0 0 0 0 0 0 1 0 19 0 0 0 38 COG2317(Zn-dependent carboxypeptidase) 120 42 44 70 8 12 15 10 3 3 3 2 5 35 6 4 4 2 14 35 47 44 67 43 32 6 24 34 47 46 36 65 34 34 65 57 14 103 63 34 17 23 0 0 0 0 0 0 0 2 0 23 0 0 1 28 COG0288(Carbonic anhydrase) 224 36 15 31 8 13 13 20 26 18 24 24 9 43 4 19 87 59 33 14 20 13 23 11 17 69 13 7 8 11 10 22 28 9 19 46 39 261 19 34 6 7 0 0 0 0 0 0 0 0 0 6 0 0 0 7 COG2385(Sporulation protein and related proteins) 65 27 44 63 7 16 5 0 1 3 0 2 0 1 2 1 28 43 4 19 68 16 94 30 77 186 34 21 43 33 59 52 16 20 6 25 7 163 82 13 10 8 0 0 0 0 0 0 0 1 0 13 0 0 0 17 NOG30348() 12 13 15 5 7 1 3 46 21 23 8 30 5 14 20 15 14 1 14 2 2 8 16 2 5 1 27 48 53 5 20 91 85 63 190 212 36 43 57 51 30 45 0 0 0 1 2 0 0 2 0 39 2 0 0 19 COG3118(Thioredoxin domain-containing protein) 102 32 38 37 4 4 7 29 9 4 11 12 3 41 20 12 23 28 17 17 13 18 24 22 17 127 18 23 14 6 15 37 20 17 49 63 14 375 24 33 9 12 0 0 0 0 0 1 0 0 0 12 0 0 0 11 COG3803(Uncharacterized protein conserved in bacteria) 140 43 41 35 3 10 8 31 11 19 20 25 8 21 19 18 12 3 22 27 17 20 29 28 19 2 32 41 22 1 19 53 43 36 162 75 27 128 54 26 15 21 0 0 0 0 0 0 0 0 0 13 0 0 0 24 NOG16530() 55 57 37 87 2 10 23 27 11 6 8 10 13 16 12 19 17 32 18 30 29 30 43 24 35 31 30 32 28 4 38 40 44 47 90 54 29 145 49 27 14 11 0 0 0 0 0 0 0 0 0 32 0 1 0 26 NOG06841() 64 86 70 86 3 11 30 5 3 6 0 0 0 5 4 1 2 0 0 20 35 38 83 52 51 10 11 42 52 0 44 33 54 37 135 88 9 23 22 66 26 21 0 1 0 0 1 0 0 2 0 44 1 0 0 45 NOG13960() 100 77 160 70 3 1 27 12 9 8 14 13 7 24 16 13 5 12 26 22 23 49 62 26 33 44 21 37 21 8 17 62 26 32 74 100 15 7 21 41 18 23 0 0 0 0 2 0 0 0 0 14 0 0 0 23 COG1213(Predicted sugar nucleotidyltransferases) 87 53 128 47 1 2 12 18 5 9 0 13 13 27 18 23 22 59 26 15 25 28 50 28 25 108 19 25 21 3 24 24 42 34 49 92 43 54 34 43 13 10 0 0 0 0 0 0 0 0 0 11 0 0 0 32 COG1778(Low specificity phosphatase (HAD superfamily)) 184 40 79 29 13 6 12 22 16 9 17 11 5 21 10 11 15 21 20 11 13 20 33 20 18 48 18 20 12 6 14 35 27 16 56 72 33 323 28 22 9 5 0 0 0 0 0 0 0 0 0 5 0 0 0 8 COG1490(D-Tyr-tRNAtyr deacylase) 119 55 109 66 12 6 23 7 15 11 11 13 18 29 17 21 13 13 15 24 32 18 36 21 21 13 15 29 30 8 8 50 35 41 98 90 26 116 10 40 30 11 0 0 0 0 0 0 0 0 0 12 0 0 1 24 COG1737(Transcriptional regulators) 523 43 13 14 7 3 14 20 10 4 20 5 9 37 22 9 10 5 25 7 9 9 15 11 1 15 19 4 1 2 6 21 18 14 59 47 61 243 10 19 4 4 0 0 0 3 0 0 0 0 0 3 0 0 0 12 COG2986(Histidine ammonia-lyase) 399 40 71 21 3 1 1 9 11 6 13 6 12 28 7 9 25 29 13 20 12 36 36 22 18 85 16 18 17 13 10 27 13 25 21 48 23 146 8 35 17 11 0 0 1 0 0 0 0 0 0 10 0 0 2 15 COG0213(Thymidine phosphorylase) 133 34 83 46 5 13 8 10 7 4 3 0 2 21 4 8 33 51 20 16 22 30 32 17 24 110 17 29 6 4 11 25 46 20 53 70 52 206 26 40 14 12 0 0 1 0 0 0 0 0 0 8 0 1 0 26 COG2423(Predicted ornithine cyclodeaminase, mu-crystallin homolog) 281 52 117 71 4 5 1 7 10 8 16 2 11 45 9 9 21 21 31 10 12 15 43 20 20 46 23 7 9 3 5 30 30 25 52 86 11 158 12 26 5 7 0 0 0 1 0 0 0 0 0 7 0 0 0 12 COG1654(Biotin operon repressor) 150 54 87 69 5 5 9 23 9 8 7 9 12 33 8 5 31 40 20 17 35 22 18 27 22 59 8 12 14 7 21 48 18 19 43 83 17 251 18 18 10 4 0 0 2 0 0 0 0 0 0 5 0 0 0 8 NOG19952() 48 84 46 84 1 6 18 23 10 13 8 18 7 15 11 22 44 25 13 35 29 38 39 41 32 24 33 22 23 0 31 37 60 52 111 145 7 0 25 37 16 10 2 0 0 0 0 0 0 0 0 16 0 0 0 28 COG0422(Thiamine biosynthesis protein ThiC) 213 41 39 70 11 12 25 12 5 13 2 8 7 40 12 17 33 27 14 12 39 29 47 37 35 55 33 22 31 21 23 34 26 14 64 41 37 110 40 14 8 3 0 0 0 0 0 0 0 0 0 6 0 0 1 6 COG4760(Predicted membrane protein) 27 56 115 53 5 8 21 4 7 7 10 7 3 28 9 11 23 54 16 22 24 29 43 23 20 110 18 19 24 11 18 43 39 33 98 78 5 168 13 22 13 14 0 1 0 0 1 0 0 0 0 13 0 0 0 19 NOG06257() 127 122 130 96 6 3 23 8 5 7 7 2 12 33 13 12 6 3 17 28 14 26 40 17 24 1 24 19 17 14 9 40 26 49 89 93 14 98 14 38 2 19 0 0 0 0 0 0 0 0 0 14 1 0 0 20 NOG08619() 61 73 57 85 3 4 16 40 16 10 11 33 17 17 16 32 24 28 23 22 22 13 24 13 8 22 27 18 13 0 7 33 40 38 103 178 22 56 35 38 17 16 0 0 0 1 0 0 0 0 0 18 0 0 0 31 COG0606(Predicted ATPase with chaperone activity) 173 19 12 14 13 11 4 7 14 13 17 16 5 44 14 7 59 51 26 5 11 5 14 8 12 155 14 3 1 4 6 25 3 15 10 21 82 396 31 9 7 4 0 0 0 0 0 0 0 0 0 3 0 0 0 17 COG3899(Predicted ATPase) 370 25 51 17 5 6 7 11 3 4 4 14 5 31 9 8 9 42 25 23 9 18 22 11 15 38 26 11 9 8 3 33 27 12 59 68 48 187 24 26 12 2 0 0 0 0 0 0 0 0 0 6 0 0 0 36 NOG15344() 141 81 77 131 11 12 32 18 2 16 10 12 8 28 7 31 18 11 20 22 18 16 52 35 15 23 8 25 27 4 8 54 39 22 93 69 18 61 16 12 21 14 0 0 1 0 0 0 0 2 0 10 0 0 0 27 COG0690(Preprotein translocase subunit SecE) 77 61 56 67 5 5 17 19 11 23 7 8 3 59 18 9 37 26 12 25 32 19 58 19 26 47 22 20 27 22 30 36 31 22 76 68 21 159 26 28 9 8 0 1 0 0 0 0 0 0 2 9 0 0 0 12 COG2840(Uncharacterized protein conserved in bacteria) 178 41 39 31 7 19 20 27 9 19 13 17 12 14 17 9 16 18 25 21 22 20 28 12 25 7 23 26 11 4 8 43 27 41 112 103 33 157 29 28 18 9 0 0 0 0 0 0 0 0 0 6 0 0 0 30 COG4583(Sarcosine oxidase gamma subunit) 97 62 53 89 3 8 17 25 14 17 8 18 8 19 12 16 7 9 23 30 20 18 36 25 42 1 36 24 25 3 28 41 47 31 108 120 21 91 19 35 16 22 0 0 1 0 0 0 0 0 0 11 0 0 0 18 COG3844(Kynureninase) 92 27 49 27 13 6 8 15 12 6 9 15 4 28 16 10 62 84 26 24 13 19 40 11 17 126 23 16 11 4 0 27 30 16 59 99 7 235 17 32 11 5 0 0 0 0 0 0 0 0 0 7 0 0 1 14 COG3027(Uncharacterized protein conserved in bacteria) 67 107 65 103 2 2 25 41 5 14 8 10 5 16 10 16 21 6 14 29 32 31 42 29 28 17 29 22 22 3 21 42 36 28 75 119 23 82 24 25 10 17 0 2 0 0 0 0 1 0 0 18 0 0 0 29 COG3761(NADH:ubiquinone oxidoreductase 17.2 kD subunit) 67 76 51 83 1 3 16 27 10 3 12 12 4 11 27 21 14 21 16 29 27 17 59 29 25 18 35 24 27 1 24 61 40 37 86 140 31 38 42 38 8 21 0 0 0 0 1 1 0 0 0 16 1 1 0 18 COG1430(Uncharacterized conserved protein) 75 58 72 52 7 7 21 10 11 7 8 7 8 32 18 11 17 14 20 23 20 17 61 33 32 48 38 14 33 47 27 45 52 15 79 62 35 101 33 30 8 13 0 1 0 1 0 0 0 1 0 16 0 0 0 29 COG1398(Fatty-acid desaturase) 139 24 32 36 8 16 6 8 5 14 15 10 10 20 3 11 31 33 22 16 30 32 53 32 26 123 11 15 25 32 15 38 41 5 12 46 44 225 38 18 9 4 0 0 0 0 2 0 0 0 0 18 0 0 0 11 COG2876(3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase) 88 41 56 35 7 7 20 11 25 11 5 19 11 43 15 22 12 17 26 32 19 24 46 31 21 65 37 32 22 7 23 34 56 28 90 130 22 38 27 31 15 18 0 0 0 0 0 0 0 0 0 16 0 0 0 29 COG1536(Flagellar motor switch protein) 215 32 66 37 7 12 9 24 4 8 17 3 15 35 20 12 8 4 17 8 22 28 50 32 32 19 30 27 38 27 17 27 39 24 53 45 26 145 20 45 10 13 0 0 0 0 0 0 1 0 0 19 0 0 0 22 COG4535(Putative Mg2+ and Co2+ transporter CorC) 133 73 77 48 7 4 19 21 7 16 7 9 4 19 16 23 36 11 29 29 22 18 49 8 21 23 17 14 24 9 6 40 32 28 65 58 18 224 25 20 11 17 0 0 0 0 0 0 0 0 0 10 0 0 0 13 COG1350(Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)) 54 62 81 77 2 6 35 2 2 1 7 4 6 13 5 3 23 6 10 44 17 27 54 19 15 37 45 42 25 0 25 38 35 34 101 167 21 71 21 31 21 15 0 0 0 0 0 0 0 0 0 9 0 0 0 45 COG3164(Predicted membrane protein) 316 63 55 32 6 4 5 29 6 19 28 9 10 34 12 26 54 57 20 17 3 3 21 12 11 26 10 11 4 1 8 9 6 2 31 32 17 325 2 5 3 4 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG4962(Flp pilus assembly protein, ATPase CpaF) 353 1 10 5 1 0 0 2 1 1 1 0 2 8 2 4 52 39 7 1 5 1 7 4 1 138 6 4 11 1 2 9 10 5 2 8 37 578 0 11 8 2 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG2165(Type II secretory pathway, pseudopilin PulG) 635 90 72 49 3 3 6 12 2 8 3 9 2 4 4 1 5 8 6 4 12 11 33 17 19 37 6 7 12 11 4 19 13 16 51 21 42 53 10 9 3 6 0 0 0 0 0 0 0 0 0 9 0 0 0 1 COG2095(Multiple antibiotic transporter) 282 18 34 18 2 2 16 24 20 18 19 27 12 35 36 19 31 63 28 12 8 16 18 7 16 125 18 7 5 4 1 21 18 18 34 67 34 153 11 21 7 4 0 0 0 0 0 0 0 0 0 4 0 0 0 12 COG1480(Predicted membrane-associated HD superfamily hydrolase) 55 31 62 57 15 6 24 13 17 9 1 15 10 8 12 6 17 2 13 17 47 31 63 49 39 6 26 20 49 14 35 33 25 29 64 59 17 203 50 31 18 14 0 0 0 0 0 0 0 0 0 4 0 0 0 25 COG5256(Translation elongation factor EF-1alpha (GTPase)) 74 33 61 47 9 5 8 20 8 12 15 12 17 42 21 13 26 31 22 32 36 30 73 26 31 40 31 13 27 15 27 20 27 29 40 85 53 106 24 34 17 14 0 0 2 0 0 0 0 2 0 13 0 0 0 18 COG1413(FOG: HEAT repeat) 148 28 51 44 21 15 5 2 8 3 9 1 5 14 8 4 13 7 12 16 36 36 51 24 40 50 25 27 17 29 16 58 10 15 12 36 26 243 112 20 12 8 0 0 0 0 0 0 0 0 0 7 0 0 1 11 COG1182(Acyl carrier protein phosphodiesterase) 313 32 22 37 1 2 10 28 9 14 11 11 2 12 15 25 14 8 13 17 14 16 27 19 16 13 21 25 18 2 18 44 26 29 105 77 25 148 19 25 12 12 0 0 0 0 0 2 0 0 0 10 0 0 0 17 COG0053(Predicted Co/Zn/Cd cation transporters) 406 14 47 23 5 3 10 8 9 3 6 5 5 44 17 14 35 35 22 20 9 11 21 12 13 76 22 15 13 4 4 17 6 20 12 50 43 196 25 7 7 1 0 0 0 0 0 0 1 0 0 6 0 0 0 14 NOG09465() 63 76 72 84 2 2 4 18 3 1 5 6 6 11 16 13 15 5 18 37 15 26 31 14 15 37 42 23 11 2 7 43 51 29 95 210 20 53 23 27 22 19 0 2 0 0 0 1 0 0 0 11 0 0 1 49 NOG09469() 83 92 132 101 6 7 25 19 10 5 0 8 8 15 5 4 0 9 4 40 26 24 55 35 30 40 22 20 23 18 13 49 42 39 104 82 3 5 34 24 15 31 0 0 1 0 0 0 0 1 0 15 0 0 0 11 COG0613(Predicted metal-dependent phosphoesterases (PHP family)) 123 24 34 33 8 8 10 8 2 2 9 5 10 28 24 12 39 67 13 14 24 13 49 30 23 140 17 20 21 12 18 37 19 14 25 67 41 186 34 12 18 2 0 0 0 0 0 0 0 0 0 11 0 0 0 28 COG1333(ResB protein required for cytochrome c biosynthesis) 130 15 14 40 16 7 5 5 9 5 6 4 3 11 11 4 57 69 25 5 27 20 38 25 53 110 9 17 18 31 17 39 22 22 60 53 19 227 45 12 13 2 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG1841(Ribosomal protein L30/L7E) 61 55 70 49 8 13 25 15 6 8 15 13 15 40 18 15 28 52 16 12 15 18 45 24 14 92 22 20 17 11 19 42 22 17 63 68 12 170 12 28 9 15 0 0 2 0 0 0 0 0 0 13 0 0 0 24 NOG20793() 5 17 28 16 2 4 10 114 40 23 38 17 35 15 12 19 15 21 35 37 12 36 74 42 37 108 37 38 47 50 23 32 37 16 39 31 6 22 17 27 11 26 2 0 0 0 0 0 0 0 0 14 0 0 0 38 COG4174(ABC-type uncharacterized transport system, permease component) 155 35 68 48 1 5 9 8 9 14 5 4 14 32 9 10 16 24 20 7 21 22 34 23 29 15 27 32 16 1 7 47 37 27 44 73 27 214 20 47 14 12 0 0 0 1 0 0 0 0 2 18 0 0 0 19 COG1861(Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog) 81 58 85 81 1 5 7 29 8 9 3 8 2 20 14 10 22 43 18 24 28 38 59 35 28 52 18 15 21 1 13 32 28 34 73 106 35 77 17 25 5 18 1 0 0 0 0 1 0 0 0 13 0 0 0 19 COG2963(Transposase and inactivated derivatives) 546 49 12 5 3 1 1 13 13 11 22 6 0 44 11 8 15 13 21 0 1 0 5 3 0 16 7 2 3 3 5 2 0 0 1 1 39 430 2 1 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4266(Allantoicase) 174 63 54 71 1 2 5 11 3 0 11 7 8 7 13 22 13 15 12 21 26 20 27 16 17 3 27 11 14 3 13 47 57 37 106 199 45 13 35 31 22 13 0 0 0 0 0 0 0 0 0 10 0 0 0 9 COG0618(Exopolyphosphatase-related proteins) 18 41 71 16 15 3 22 16 17 3 1 12 3 19 20 29 21 15 23 28 46 25 49 22 16 36 24 28 31 12 17 36 50 32 66 79 58 116 26 52 26 31 0 0 0 0 2 0 0 0 0 8 0 1 0 30 COG3848(Phosphohistidine swiveling domain) 68 47 24 47 0 0 4 14 15 6 11 20 8 16 10 9 34 22 7 28 30 19 53 40 40 35 26 35 28 18 28 36 47 17 67 78 45 169 21 33 10 18 0 0 0 0 0 0 0 0 0 4 0 0 0 25 COG0724(RNA-binding proteins (RRM domain)) 70 62 85 58 46 50 12 10 6 12 2 10 6 28 5 6 9 10 15 47 41 22 52 27 31 19 17 20 34 56 24 38 27 9 32 44 25 108 65 16 20 8 0 0 2 0 0 0 0 0 0 11 1 2 0 10 NOG06109() 104 48 101 39 12 4 28 6 15 7 7 3 6 30 12 13 4 10 18 12 14 44 51 26 26 11 18 41 11 11 19 44 52 34 120 106 16 52 24 41 23 9 0 2 0 0 2 0 0 0 0 17 0 0 0 16 COG1168(Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities) 31 45 68 45 2 11 5 3 4 8 5 5 12 20 7 7 39 51 38 20 20 14 30 18 11 83 17 12 5 13 17 28 19 22 48 30 28 366 18 21 6 22 0 2 0 0 0 0 0 0 0 11 0 0 0 19 COG1760(L-serine deaminase) 238 23 62 31 3 2 2 21 4 7 10 11 4 57 12 5 20 49 28 10 7 11 23 12 4 92 16 12 7 8 0 26 9 13 57 42 16 282 7 29 9 6 0 0 0 0 0 0 0 0 0 5 0 0 0 14 COG2378(Predicted transcriptional regulator) 337 16 23 8 4 0 7 1 4 2 3 0 5 15 0 7 53 67 9 6 6 11 2 1 10 199 16 5 10 2 0 13 7 3 23 28 24 363 5 2 2 4 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG06505(Photosystem II protein) 36 7 3 26 10 9 10 47 10 2 0 4 13 6 2 3 3 5 8 37 52 20 64 38 38 48 22 47 66 95 44 53 30 27 27 14 4 76 93 19 34 26 0 0 0 0 4 4 0 0 0 20 0 1 0 97 COG1502(Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes) 874 13 12 7 6 4 2 7 2 11 6 2 4 15 9 0 15 8 8 4 2 1 5 0 3 26 8 3 7 5 0 14 1 2 2 20 20 162 8 2 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG04772(Alkane-1 monooxygenase) 98 50 94 36 15 6 18 12 13 9 9 6 6 19 10 10 9 5 12 26 19 39 47 19 22 10 25 23 40 4 19 45 49 39 111 117 9 49 27 51 29 11 0 0 0 0 0 0 0 0 2 17 0 0 0 17 COG0027(Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)) 200 38 31 45 6 13 17 18 7 6 12 11 9 18 4 7 32 29 18 9 45 33 54 28 33 24 25 13 24 18 26 44 19 10 39 61 24 128 36 26 10 14 2 0 0 0 0 0 0 0 0 16 0 1 1 18 COG2376(Dihydroxyacetone kinase) 189 69 64 76 3 3 26 19 5 4 2 5 0 19 10 7 24 24 9 18 17 7 59 23 14 21 18 23 28 9 20 30 17 20 62 133 14 130 12 10 6 19 0 0 0 0 0 0 0 0 0 15 0 3 0 15 COG4598(ABC-type histidine transport system, ATPase component) 499 24 26 26 3 6 8 12 12 13 6 5 9 29 2 7 12 12 14 14 20 1 16 12 6 16 10 16 11 6 7 36 20 20 63 37 22 147 18 26 10 11 0 0 0 0 0 0 0 0 0 11 0 0 0 18 NOG18174() 82 84 47 89 0 1 21 39 6 18 4 15 1 9 14 19 15 4 14 32 36 25 43 39 24 0 26 27 28 0 17 50 51 39 128 124 11 6 17 38 12 17 0 0 0 0 0 0 0 0 0 11 1 0 0 13 COG2142(Succinate dehydrogenase, hydrophobic anchor subunit) 85 55 47 27 5 4 17 17 10 3 10 12 9 23 20 18 16 13 15 18 27 8 36 24 24 5 21 17 31 1 13 26 26 24 75 53 18 302 26 31 19 25 0 1 0 0 0 0 0 0 0 14 0 0 0 25 COG0384(Predicted epimerase, PhzC/PhzF homolog) 171 85 109 61 8 9 16 16 5 14 6 12 11 24 8 13 17 14 11 21 15 19 32 19 14 15 22 7 20 10 4 46 32 24 93 55 21 102 25 32 8 9 0 0 1 0 0 0 0 0 0 22 0 2 0 15 COG3743(Uncharacterized conserved protein) 88 21 28 31 4 4 15 21 9 6 6 16 4 22 8 8 27 47 23 28 13 21 31 9 13 99 32 15 18 13 18 32 31 16 54 95 15 206 24 32 18 23 1 2 0 0 0 0 0 0 0 7 2 0 0 35 COG0656(Aldo/keto reductases, related to diketogulonate reductase) 174 58 71 51 13 22 6 15 13 5 2 7 10 34 15 13 16 24 17 27 14 17 33 21 13 29 34 15 16 22 8 25 32 30 37 57 32 157 19 21 12 16 0 0 0 0 0 0 2 0 0 6 0 1 0 26 COG2183(Transcriptional accessory protein) 243 39 48 32 9 7 18 12 8 11 11 11 13 16 8 6 37 36 15 20 30 19 31 10 22 48 38 33 12 12 11 27 22 12 59 63 43 127 7 19 5 14 0 0 0 0 1 0 0 0 0 8 0 2 0 13 NOG25756() 35 12 29 28 4 30 5 19 12 4 11 2 6 46 8 15 19 11 43 16 36 35 14 11 14 54 4 15 7 13 3 19 12 4 10 15 8 613 15 6 0 10 0 0 0 0 0 0 0 0 0 13 0 0 0 1 COG1347(Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD) 112 73 91 58 18 5 42 16 15 4 11 11 21 7 9 13 2 3 24 18 20 20 31 23 20 0 18 35 22 5 9 45 19 31 124 85 21 103 6 35 11 20 0 0 0 0 0 0 0 0 0 12 0 1 0 18 COG4623(Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein) 209 49 35 25 4 3 12 38 15 2 4 7 15 35 15 20 17 19 18 10 25 14 28 12 14 1 9 11 10 3 4 41 34 18 44 71 40 277 12 23 10 11 0 0 0 0 0 0 0 0 0 11 0 0 0 9 COG1246(N-acetylglutamate synthase and related acetyltransferases) 273 21 18 22 2 4 5 19 5 14 16 12 2 21 15 18 57 74 25 2 5 7 12 8 7 76 18 5 5 3 0 15 5 9 31 45 39 345 0 5 3 7 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG08813() 15 27 139 37 28 2 28 3 24 13 17 15 13 6 11 8 9 12 19 11 18 49 49 21 15 15 30 29 28 2 11 45 37 33 86 74 11 177 10 46 15 18 0 0 0 0 0 0 0 0 0 13 0 0 0 15 COG0800(2-keto-3-deoxy-6-phosphogluconate aldolase) 152 41 23 36 15 14 15 25 8 5 14 21 9 42 14 7 22 16 35 10 32 7 42 22 34 48 18 21 18 13 24 29 28 27 90 49 39 97 37 27 14 8 0 0 0 0 0 0 0 0 0 16 0 0 0 13 COG0837(Glucokinase) 124 48 56 36 10 15 11 16 8 12 11 10 2 33 22 7 6 6 17 16 38 10 63 34 48 8 21 24 21 19 39 48 44 30 96 68 20 72 35 24 7 13 2 0 0 0 0 0 0 0 0 10 0 0 0 16 COG2386(ABC-type transport system involved in cytochrome c biogenesis, permease component) 73 74 91 55 7 9 17 20 5 18 12 6 2 40 16 12 11 18 24 16 20 19 41 10 29 22 29 20 15 4 7 46 21 28 72 66 31 168 18 30 14 9 0 0 0 0 0 0 2 0 0 13 0 0 0 15 COG1193(Mismatch repair ATPase (MutS family)) 152 22 20 48 13 7 12 17 7 10 11 11 4 17 2 3 11 4 2 18 47 27 54 32 42 24 23 28 41 29 46 63 49 17 51 22 10 145 46 37 15 5 0 0 0 0 0 0 0 0 0 10 0 0 0 21 COG4973(Site-specific recombinase XerC) 182 84 95 61 3 3 18 15 6 6 6 12 5 24 14 16 12 11 24 17 11 15 44 21 10 15 19 8 20 6 16 29 31 14 61 62 26 164 28 12 15 8 0 0 0 0 0 0 0 0 0 17 0 0 0 7 COG2209(Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE) 99 70 78 53 16 5 37 14 16 7 15 7 20 13 8 11 2 1 18 22 14 37 33 19 27 1 14 36 21 3 14 43 17 31 124 82 24 104 10 51 13 13 0 0 0 0 0 0 0 0 0 11 0 1 0 16 COG0788(Formyltetrahydrofolate hydrolase) 188 27 40 33 9 9 11 8 1 3 18 4 8 35 12 6 20 44 12 2 31 15 31 19 25 54 25 20 25 10 26 18 22 4 48 24 26 303 26 11 5 2 0 0 0 0 0 0 0 0 0 2 0 0 0 7 COG2109(ATP:corrinoid adenosyltransferase) 137 22 29 75 4 10 4 10 1 7 10 5 5 20 9 8 5 0 10 10 55 30 84 65 73 13 14 23 38 38 69 48 23 10 34 25 16 120 59 21 4 6 0 0 1 1 0 0 0 1 0 4 1 0 0 11 COG0555(ABC-type sulfate transport system, permease component) 291 39 52 65 4 1 6 25 5 7 10 14 10 6 16 5 14 30 7 24 14 19 42 23 14 53 32 24 16 4 8 48 28 24 63 58 11 80 14 29 14 2 0 0 0 0 0 0 0 0 0 4 0 0 0 12 COG0796(Glutamate racemase) 99 31 50 19 17 7 10 8 11 4 19 14 12 17 7 2 52 81 19 7 32 17 34 15 21 155 16 16 22 23 21 32 12 8 50 46 20 145 22 34 10 7 0 0 0 2 1 0 0 0 0 9 0 0 0 10 NOG13477() 52 65 63 102 2 4 23 33 12 16 9 28 4 10 25 24 34 20 16 38 31 19 37 25 30 17 41 35 22 1 17 42 47 25 85 101 15 0 14 29 8 7 0 0 0 0 0 0 0 0 0 13 1 0 0 24 COG1330(Exonuclease V gamma subunit) 291 32 13 52 4 14 4 2 2 2 4 0 2 8 4 3 10 8 9 11 61 19 49 29 44 22 9 21 13 34 24 19 11 10 13 5 34 321 41 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG0239(Integral membrane protein possibly involved in chromosome condensation) 92 35 52 34 7 4 13 18 21 15 9 13 7 20 12 13 14 28 25 38 30 13 36 16 27 68 17 14 15 10 10 42 42 24 95 86 25 116 26 23 13 15 0 2 0 0 2 0 0 0 0 10 0 0 0 17 NOG11127() 44 79 64 99 3 7 19 22 13 9 15 18 11 18 4 11 15 21 15 20 18 23 32 23 34 27 21 27 20 1 29 37 39 29 98 93 14 63 30 27 13 10 0 0 0 0 0 0 0 1 0 16 0 0 0 26 COG4152(ABC-type uncharacterized transport system, ATPase component) 230 35 37 35 3 4 8 15 17 6 6 20 15 34 18 11 25 16 9 17 25 15 23 7 10 53 6 15 14 0 8 33 21 22 65 54 26 188 19 29 15 16 0 0 0 0 0 0 0 0 0 23 0 0 0 9 COG3525(N-acetyl-beta-hexosaminidase) 198 51 107 42 10 16 18 11 20 8 11 16 7 28 10 5 10 20 28 15 21 18 23 19 26 26 34 16 14 15 10 38 40 36 64 81 5 29 20 41 14 9 0 0 0 0 0 0 0 0 0 11 1 0 0 15 COG0447(Dihydroxynaphthoic acid synthase) 67 37 33 64 16 7 11 11 8 3 7 9 4 13 8 14 56 41 16 18 26 26 69 24 23 122 10 18 14 6 28 27 19 13 34 49 14 218 23 23 6 7 0 0 0 0 0 0 0 0 0 6 0 0 0 7 COG1169(Isochorismate synthase) 187 10 27 33 19 13 4 14 11 7 4 5 2 5 12 7 52 55 12 3 28 7 41 20 15 126 11 7 12 29 23 28 16 8 14 42 5 285 21 16 2 8 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG1607(Acyl-CoA hydrolase) 201 36 79 32 11 6 12 6 9 6 10 4 7 18 11 9 14 8 18 9 28 23 38 9 20 55 12 18 15 14 3 27 17 10 48 51 27 262 14 17 7 9 0 0 0 0 0 0 0 0 0 7 0 0 0 15 COG1838(Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain) 128 18 13 20 9 4 9 19 7 15 7 4 6 47 8 15 55 93 28 12 7 13 20 9 10 150 26 16 8 5 4 23 19 14 17 35 31 279 6 19 4 4 0 0 0 0 0 0 0 0 0 3 0 0 0 8 COG4753(Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain) 557 19 32 10 6 1 7 11 2 9 13 0 5 23 4 4 5 17 17 10 4 5 21 6 11 45 10 9 5 10 7 17 5 9 29 18 63 181 8 9 6 4 0 0 0 0 0 0 0 0 0 3 0 0 0 8 NOG10604() 1 8 17 21 2 2 5 83 13 7 29 6 9 14 10 6 8 18 13 19 39 34 88 55 56 134 25 31 63 70 35 24 25 25 20 33 2 1 61 15 29 10 0 0 0 0 0 0 0 0 0 7 0 0 0 70 COG2987(Urocanate hydratase) 189 31 71 21 2 3 4 5 12 5 12 6 17 27 10 9 40 22 15 31 26 40 34 15 18 87 19 24 13 8 13 33 22 11 22 72 18 115 4 39 23 19 0 0 0 0 0 2 0 0 0 12 0 0 0 21 COG4249(Uncharacterized protein containing caspase domain) 123 50 35 52 10 30 19 23 9 15 3 16 14 29 8 2 23 9 19 18 18 27 40 20 21 41 34 18 16 5 32 23 25 33 65 107 29 100 11 20 9 18 0 0 0 0 0 0 0 0 0 8 0 0 0 15 COG2068(Uncharacterized MobA-related protein) 120 22 44 52 4 9 19 13 7 5 13 13 10 35 14 20 12 11 12 23 35 30 40 28 31 27 25 11 18 1 15 25 25 49 54 83 12 158 23 28 6 21 0 2 0 0 0 0 0 0 0 9 0 0 0 26 COG1204(Superfamily II helicase) 49 19 63 24 12 12 2 8 4 3 1 5 6 10 19 5 16 9 19 19 28 36 30 18 5 79 17 11 16 18 8 39 58 29 17 51 28 326 17 32 25 8 0 0 0 0 0 0 0 0 0 2 0 0 0 37 NOG24186() 70 92 49 74 2 3 17 21 11 10 5 11 5 10 11 12 11 15 10 35 10 23 38 22 23 0 26 37 16 1 18 49 38 37 86 116 23 70 36 34 11 11 0 0 0 0 1 0 0 0 2 19 0 0 0 19 COG1763(Molybdopterin-guanine dinucleotide biosynthesis protein) 305 36 33 31 3 7 16 10 1 9 8 3 10 20 9 7 23 9 13 11 12 18 32 16 20 24 22 9 13 1 8 24 24 34 70 68 19 145 30 35 19 10 0 0 0 0 2 0 0 0 1 7 0 0 0 13 COG0634(Hypoxanthine-guanine phosphoribosyltransferase) 86 21 62 28 4 14 8 20 7 10 6 7 8 33 25 12 40 44 14 11 15 10 32 12 32 112 25 21 17 4 9 25 25 25 46 85 29 161 17 19 9 17 0 0 0 0 0 0 0 0 0 9 0 0 0 21 COG1291(Flagellar motor component) 255 43 97 26 4 5 10 15 4 4 13 7 1 29 12 7 7 6 13 20 18 24 49 21 30 25 28 32 12 2 9 23 16 10 39 49 37 148 18 20 7 10 0 4 0 0 0 0 0 2 0 11 0 0 0 14 COG1766(Flagellar biosynthesis/type III secretory pathway lipoprotein) 179 37 23 26 5 6 11 31 4 4 7 0 17 28 14 7 16 14 13 22 13 9 43 30 21 14 31 4 14 2 9 23 33 24 58 36 20 254 29 36 14 13 0 0 0 0 1 0 2 0 0 14 0 0 0 22 COG1664(Integral membrane protein CcmA involved in cell shape determination) 101 55 71 49 7 13 18 17 8 5 21 5 4 21 10 14 24 17 16 13 14 28 42 22 23 39 18 26 13 3 14 36 25 34 100 64 9 122 23 38 15 5 0 0 0 0 0 0 0 0 0 10 0 0 0 20 COG2902(NAD-specific glutamate dehydrogenase) 312 28 22 19 5 2 5 8 0 2 27 3 2 28 2 4 13 18 10 11 5 4 21 7 8 18 2 9 6 8 3 2 0 0 8 10 37 551 3 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG4674(Uncharacterized ABC-type transport system, ATPase component) 452 37 16 30 2 14 16 16 5 6 11 1 4 14 4 4 5 2 10 15 19 24 48 16 18 19 12 7 22 11 12 26 13 8 39 19 10 192 25 8 8 4 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG1124(ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component) 310 36 27 39 6 4 10 10 9 5 10 8 12 42 13 10 12 22 14 16 14 19 45 16 15 40 4 12 9 3 8 29 28 22 61 36 28 119 41 36 6 12 0 0 0 0 0 0 0 0 0 7 0 0 0 6 COG3540(Phosphodiesterase/alkaline phosphatase D) 204 60 54 26 9 12 31 7 9 19 9 6 6 15 10 7 11 6 21 9 16 22 51 23 18 38 19 23 10 14 11 38 38 24 85 29 8 187 8 12 8 8 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG3177(Uncharacterized conserved protein) 136 4 3 1 1 3 1 0 0 0 13 2 1 18 10 2 16 29 11 2 2 0 3 1 1 33 5 0 1 2 2 2 2 0 8 8 152 750 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG0732(Restriction endonuclease S subunits) 232 40 45 25 7 5 7 13 6 7 11 12 2 23 10 9 16 14 17 14 27 10 41 15 25 54 12 16 12 13 12 23 32 16 40 50 32 209 12 18 6 5 0 0 0 0 0 0 0 0 0 9 0 0 0 21 COG1921(Selenocysteine synthase [seryl-tRNASer selenium transferase]) 137 35 102 54 3 8 12 2 9 1 0 10 11 24 16 14 12 14 25 14 26 32 61 17 26 53 32 32 26 3 19 22 28 27 46 107 16 29 25 20 19 8 0 0 0 0 2 0 0 0 0 11 0 0 0 30 COG2869(Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC) 112 72 90 35 16 10 38 18 17 4 10 8 17 12 18 11 7 4 23 17 19 12 33 22 16 0 14 26 18 5 12 38 30 26 108 85 14 112 15 29 9 19 0 0 0 1 0 0 0 0 0 12 0 0 0 6 COG1733(Predicted transcriptional regulators) 343 15 16 6 2 4 5 46 23 20 24 34 36 55 27 38 28 20 20 24 3 15 12 10 7 7 24 17 7 5 2 28 31 15 57 43 20 58 13 19 15 4 0 0 0 0 1 0 0 0 0 5 0 0 1 14 COG0758(Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake) 160 10 17 7 11 10 4 12 2 19 13 4 11 40 4 4 59 84 29 6 2 7 20 6 3 125 9 8 6 5 4 13 9 6 0 22 86 323 36 8 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 10 NOG23457() 66 97 61 91 4 2 20 14 12 5 2 12 9 13 19 25 14 7 14 19 36 26 39 28 28 1 14 30 26 1 20 37 30 27 71 146 21 9 26 26 18 15 0 0 0 0 0 0 0 0 0 10 0 0 0 27 COG0392(Predicted integral membrane protein) 219 21 47 32 8 4 6 3 3 1 4 12 2 8 4 8 16 7 2 14 30 31 35 21 32 70 24 28 11 24 43 25 12 16 32 46 22 178 35 20 13 11 0 0 0 0 0 0 0 0 0 11 0 3 1 23 NOG06013() 33 64 78 48 11 1 36 9 12 7 21 22 6 24 16 6 10 0 8 25 20 23 33 13 28 12 22 26 16 4 20 46 42 19 156 94 3 57 27 54 11 8 0 0 0 0 0 0 0 0 0 14 1 0 0 28 COG1002(Type II restriction enzyme, methylase subunits) 271 11 21 18 8 3 4 8 7 9 3 9 2 16 1 3 29 18 16 3 8 8 27 7 3 49 13 9 4 4 12 10 8 6 14 24 23 475 5 11 6 8 0 0 0 0 0 0 0 0 0 11 0 0 0 7 COG0797(Lipoproteins) 129 40 62 34 9 5 6 10 7 15 15 6 9 17 11 17 11 11 13 9 8 22 31 15 12 63 19 7 5 7 20 29 19 14 29 50 38 312 25 14 9 7 0 2 0 0 0 0 0 0 0 9 0 0 0 8 COG1281(Disulfide bond chaperones of the HSP33 family) 156 24 11 26 5 16 12 13 4 8 16 1 2 37 14 16 19 11 21 11 36 13 49 28 18 15 20 8 24 15 26 26 29 18 45 26 16 279 28 33 7 15 0 0 0 0 0 0 0 0 0 8 1 0 0 4 COG1788(Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit) 292 35 33 28 5 12 6 10 7 11 35 6 10 31 2 10 23 21 28 12 10 19 19 13 9 42 27 15 11 2 6 31 28 24 25 33 4 224 11 9 8 9 0 0 0 0 0 2 0 0 0 2 0 0 0 8 COG2216(High-affinity K+ transport system, ATPase chain B) 452 10 13 8 0 0 9 4 3 0 0 3 0 3 0 7 7 11 5 1 9 3 17 5 4 20 15 5 5 1 5 8 22 10 4 15 10 436 23 11 3 5 0 2 0 0 0 0 0 0 0 9 0 0 0 23 COG4167(ABC-type antimicrobial peptide transport system, ATPase component) 71 53 36 32 0 5 11 19 10 16 0 12 7 10 12 6 21 28 28 6 32 18 55 35 28 26 11 13 27 5 30 26 29 30 87 61 18 175 24 36 12 18 0 0 0 0 0 0 0 0 0 15 1 0 0 6 COG2073(Cobalamin biosynthesis protein CbiG) 226 49 51 79 7 19 6 5 4 6 5 4 5 44 15 5 0 3 5 7 39 29 57 50 47 8 2 24 21 19 37 44 22 2 14 23 2 124 46 12 2 12 0 4 0 1 4 0 0 0 0 9 0 0 0 2 COG1463(ABC-type transport system involved in resistance to organic solvents, periplasmic component) 202 18 21 48 8 8 11 19 7 10 6 8 5 27 7 5 11 16 13 12 20 19 35 24 22 32 28 16 17 15 24 24 18 17 58 37 37 204 30 18 8 12 0 0 0 0 0 0 0 0 0 14 0 0 0 10 COG1257(Hydroxymethylglutaryl-CoA reductase) 16 44 96 40 15 5 24 6 16 17 6 13 7 21 18 7 7 5 21 28 26 44 47 16 22 12 36 19 15 10 11 41 43 37 85 56 52 56 25 57 26 18 0 0 0 0 0 0 1 0 0 10 0 0 0 23 COG5476(Uncharacterized conserved protein) 170 46 67 55 6 7 17 7 11 12 8 19 11 41 15 10 10 9 24 19 29 23 39 15 35 28 38 23 21 3 4 22 18 25 50 101 12 55 27 19 7 20 0 0 0 2 0 0 0 0 0 14 0 0 0 6 COG4765(Uncharacterized protein conserved in bacteria) 61 64 38 75 3 4 11 17 8 5 10 18 2 11 27 24 17 17 17 27 33 15 42 27 23 1 31 25 18 0 21 49 36 29 75 149 28 12 22 34 10 22 0 0 0 0 0 2 0 0 0 13 0 0 0 21 COG1376(Uncharacterized protein conserved in bacteria) 91 43 38 38 7 8 6 16 8 12 4 9 8 20 9 8 5 5 12 11 5 14 20 17 17 28 13 17 19 14 10 41 41 19 85 45 19 287 63 21 10 10 0 0 0 0 0 0 0 0 0 10 0 0 2 6 COG0153(Galactokinase) 102 41 49 45 12 4 13 11 11 11 4 17 13 11 11 6 33 52 21 20 16 25 35 24 27 103 16 14 19 5 7 24 29 36 113 51 2 48 27 41 9 11 0 0 0 1 0 0 0 0 0 8 0 0 0 12 COG3451(Type IV secretory pathway, VirB4 components) 975 5 7 1 1 0 0 0 0 0 0 2 0 19 0 4 22 8 1 1 2 0 2 0 0 2 5 0 3 0 0 0 0 2 2 0 69 48 4 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG3552(Protein containing von Willebrand factor type A (vWA) domain) 31 21 63 26 1 6 12 15 7 5 4 4 7 34 8 20 16 27 32 26 21 14 47 24 22 86 37 29 17 1 18 22 36 23 42 103 6 174 22 26 12 9 0 0 0 0 0 0 0 0 0 12 0 0 0 21 COG2605(Predicted kinase related to galactokinase and mevalonate kinase) 38 41 73 46 2 7 19 14 1 6 7 6 5 12 23 8 25 27 13 38 30 43 54 18 28 71 24 30 22 20 26 35 32 20 57 105 21 41 6 25 18 17 0 0 0 0 0 0 0 0 0 9 0 0 0 23 COG0693(Putative intracellular protease/amidase) 527 24 23 28 7 11 9 19 12 16 10 10 20 23 12 6 23 11 16 7 14 12 13 9 7 9 12 5 11 7 5 26 11 13 44 36 15 85 8 6 7 2 0 0 0 0 0 0 0 0 0 6 0 0 0 9 NOG19738() 52 73 42 78 4 3 17 17 5 2 4 14 8 19 9 17 2 3 23 30 30 17 34 24 29 27 26 31 16 2 14 40 30 25 85 156 17 32 22 40 14 16 0 2 0 0 0 0 0 0 0 11 0 0 0 24 NOG10237() 135 2 25 21 11 4 6 13 1 8 9 0 0 35 10 12 22 33 19 10 9 5 12 7 14 83 14 10 8 6 13 20 14 20 25 19 11 431 41 13 9 8 0 1 0 0 0 0 0 0 0 6 0 0 0 11 COG3243(Poly(3-hydroxyalkanoate) synthetase) 184 16 12 11 5 9 5 4 3 4 10 4 0 25 6 6 45 40 18 4 5 13 9 13 7 82 14 18 6 1 4 21 7 6 28 15 49 444 3 12 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 12 NOG24892() 20 35 103 46 13 4 35 29 34 1 17 10 9 13 6 3 6 15 17 16 13 41 49 21 27 20 10 35 10 2 5 38 32 22 78 62 13 155 25 37 17 9 0 0 0 0 0 0 0 0 0 11 0 0 0 18 COG2703(Hemerythrin) 987 23 12 1 0 0 1 0 0 0 0 4 2 3 0 1 11 12 5 0 0 0 3 3 0 7 5 0 0 5 1 0 1 0 0 5 61 25 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3492(Uncharacterized protein conserved in bacteria) 41 71 63 79 5 8 10 34 9 8 11 21 9 18 14 23 16 17 21 21 21 17 26 15 12 0 14 27 28 1 18 40 27 29 90 136 31 53 23 28 10 12 0 1 0 0 0 0 0 0 0 10 0 0 0 13 COG2115(Xylose isomerase) 116 27 40 44 15 8 16 20 3 8 6 9 5 23 6 6 22 19 8 15 17 21 29 15 13 107 13 13 13 7 12 29 31 37 103 59 6 104 33 38 17 18 0 0 0 0 0 0 0 2 0 15 0 0 0 13 COG1982(Arginine/lysine/ornithine decarboxylases) 477 15 10 24 7 5 2 0 0 0 2 1 0 9 0 2 75 28 2 2 23 11 50 20 20 19 7 12 23 23 16 28 2 3 11 4 45 147 24 11 3 0 0 0 0 0 0 0 0 0 0 11 0 0 0 6 COG0221(Inorganic pyrophosphatase) 112 21 13 26 11 11 5 3 2 3 6 3 0 28 5 5 55 27 9 6 27 18 56 31 35 34 12 11 23 25 25 27 11 4 21 17 41 340 33 8 6 2 0 0 0 0 0 0 0 0 0 8 0 0 1 5 COG0738(Fucose permease) 321 26 15 3 17 5 11 8 24 20 24 9 15 11 9 3 6 6 9 18 7 11 12 4 5 50 16 10 11 6 6 23 25 20 56 34 9 249 6 27 10 8 0 0 0 1 0 0 0 0 0 2 0 0 0 3 COG0599(Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit) 258 22 37 33 3 11 17 13 6 11 11 9 9 32 3 9 10 24 16 11 18 13 25 17 19 20 12 13 6 5 14 20 13 6 39 53 29 251 12 17 3 9 0 0 2 0 0 0 1 0 0 5 0 0 0 4 COG0431(Predicted flavoprotein) 397 24 39 27 10 5 10 1 14 2 7 8 3 25 8 12 12 11 9 14 18 7 33 14 6 7 11 11 15 8 5 34 30 14 46 33 23 118 23 27 16 7 0 0 0 0 0 0 0 0 0 6 0 0 0 20 COG1119(ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA) 326 18 20 13 1 8 1 3 4 4 1 1 5 20 2 3 27 39 23 17 24 32 26 19 37 72 11 9 18 19 28 14 9 2 7 31 12 229 22 1 2 3 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG11930() 97 45 35 49 1 4 18 16 6 8 12 15 4 20 10 28 15 11 23 48 24 25 20 15 15 17 40 33 16 0 13 38 33 32 79 69 22 117 21 25 15 6 0 0 0 0 0 0 0 0 0 0 0 0 0 28 COG5522(Predicted integral membrane protein) 35 113 175 68 7 4 21 18 17 6 5 11 8 12 10 10 4 6 6 13 12 24 50 30 27 3 10 26 18 8 17 42 24 22 115 67 7 5 15 55 11 8 0 0 0 0 0 0 0 0 0 10 0 0 0 13 COG4198(Uncharacterized conserved protein) 56 84 128 67 3 7 9 16 5 3 3 7 4 26 6 3 8 10 11 18 16 15 28 12 15 39 15 24 16 0 9 32 36 30 63 182 26 36 23 34 12 16 0 0 0 0 0 0 0 0 0 5 0 0 0 8 COG5336(Uncharacterized protein conserved in bacteria) 55 62 44 90 0 3 33 26 11 14 6 20 9 9 16 27 16 22 11 32 32 19 31 26 16 3 28 25 20 1 22 24 38 39 89 113 14 2 26 31 13 14 0 0 0 0 0 0 0 0 0 9 1 0 0 24 COG2360(Leu/Phe-tRNA-protein transferase) 124 34 24 29 16 10 11 12 10 18 15 3 6 38 20 9 10 17 23 22 16 9 25 19 12 56 17 15 13 6 6 37 25 22 69 79 27 184 14 18 10 10 0 0 0 0 0 0 0 0 0 7 0 0 0 17 COG3284(Transcriptional activator of acetoin/glycerol metabolism) 408 11 12 7 1 1 0 14 9 15 21 23 9 16 19 27 8 9 21 36 5 8 18 5 8 3 26 34 6 0 9 32 25 8 68 38 31 115 14 10 16 0 0 0 0 0 0 0 0 0 0 1 0 0 0 16 COG4786(Flagellar basal body rod protein) 229 24 25 27 14 16 14 18 5 4 6 6 4 27 8 7 5 11 16 15 15 17 27 25 13 12 23 14 18 9 5 31 26 22 60 33 38 202 15 38 3 11 0 0 0 0 0 0 0 0 0 4 0 0 0 19 COG3349(Uncharacterized conserved protein) 211 17 20 53 10 17 6 17 0 4 0 0 2 2 2 2 2 3 5 4 51 14 98 43 40 1 3 11 43 58 32 53 7 13 27 4 1 167 89 6 1 6 0 0 0 0 1 0 0 2 0 11 0 0 0 0 NOG06410(GH3 auxin-responsive promoter protein) 12 22 29 19 19 2 31 19 24 14 14 20 9 3 16 13 19 28 7 12 13 24 27 18 7 12 27 27 22 9 14 62 49 31 149 122 10 20 29 71 39 15 0 0 2 0 0 0 0 1 0 13 0 0 0 14 COG3894(Uncharacterized metal-binding protein) 60 40 59 42 6 5 13 14 10 11 11 9 16 27 17 14 11 16 45 30 15 13 45 21 19 38 25 12 9 3 13 37 21 19 80 74 17 124 30 41 6 17 0 0 0 0 0 0 0 0 0 5 0 0 0 18 NOG19290() 63 79 48 86 1 3 16 15 10 3 9 5 3 2 4 34 14 10 12 29 17 23 34 26 13 2 22 35 28 1 22 48 24 35 103 117 19 3 26 42 10 16 2 0 0 0 0 0 0 0 0 14 1 1 0 27 COG3840(ABC-type thiamine transport system, ATPase component) 98 24 21 16 2 3 7 13 4 9 3 3 8 20 12 11 4 8 12 18 16 12 21 13 9 10 15 21 13 5 15 41 21 29 80 76 22 349 16 19 15 12 0 0 0 0 0 0 0 0 0 7 0 0 0 21 COG1157(Flagellar biosynthesis/type III secretory pathway ATPase) 202 30 26 25 9 10 6 13 6 11 4 9 12 36 15 12 18 14 17 13 6 11 34 20 18 23 20 8 25 8 11 31 28 15 52 38 29 204 12 27 13 8 0 0 0 0 0 1 0 0 0 7 0 0 2 14 COG3245(Cytochrome c5) 532 31 32 16 4 0 8 6 9 8 16 8 8 36 17 12 24 13 11 7 6 9 22 11 9 14 10 5 5 5 3 8 6 6 29 28 21 127 8 2 2 5 0 0 0 0 0 2 0 0 0 4 0 0 0 7 COG2373(Large extracellular alpha-helical protein) 651 2 12 13 2 4 2 9 13 0 0 4 6 8 6 6 12 10 11 9 0 9 5 7 1 22 21 2 2 6 2 10 14 6 21 17 48 139 10 4 6 8 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1205(Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster) 179 17 34 12 2 5 4 0 0 4 5 3 4 13 20 4 15 23 22 14 14 19 22 21 18 71 10 14 8 14 4 11 10 8 15 14 23 401 11 8 11 7 0 2 0 0 0 0 0 0 0 8 0 0 0 25 COG4168(ABC-type antimicrobial peptide transport system, permease component) 82 47 66 50 2 15 16 18 6 11 3 5 5 21 23 8 21 30 10 22 34 25 44 21 32 36 16 15 16 3 15 35 33 26 58 58 17 104 22 24 10 16 0 0 0 0 0 0 0 0 0 6 0 0 0 20 COG2057(Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit) 244 29 39 28 4 14 11 11 12 11 24 11 14 21 4 14 23 18 24 25 16 14 27 17 15 42 22 15 12 5 11 28 26 23 19 42 9 174 9 13 10 7 0 0 0 0 0 1 0 0 0 2 0 0 0 7 COG4103(Uncharacterized protein conserved in bacteria) 60 83 68 49 9 8 20 16 8 14 10 12 6 28 10 8 3 2 22 26 12 14 26 21 17 1 30 12 18 1 13 35 34 19 110 72 13 150 12 25 9 9 0 0 0 0 0 0 0 0 0 12 0 0 0 19 NOG16995() 26 43 39 56 5 13 25 61 18 16 16 22 21 46 25 9 17 15 15 24 24 9 44 27 16 44 43 13 15 19 18 36 37 17 39 78 17 50 14 21 9 13 2 0 0 0 0 0 0 0 0 12 0 0 0 17 COG2137(Uncharacterized protein conserved in bacteria) 105 44 80 34 8 5 10 5 6 6 5 13 6 27 16 6 39 28 14 19 8 17 35 9 20 65 13 13 8 8 12 19 19 9 68 48 32 217 7 15 10 3 0 0 0 0 0 0 0 0 0 5 1 0 0 7 NOG06040() 117 36 45 57 4 24 35 0 0 0 5 0 0 5 0 2 0 0 11 8 45 48 142 81 76 38 4 2 0 3 1 0 0 0 3 0 8 342 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11046(Glutathione S-transferase) 60 45 34 56 4 13 8 17 10 20 16 6 14 35 8 12 16 9 18 25 35 27 35 28 33 11 15 20 22 26 21 55 27 30 89 55 21 57 33 26 15 8 0 0 0 0 0 0 0 0 0 14 0 0 0 12 COG1541(Coenzyme F390 synthetase) 166 24 27 15 5 12 8 11 6 10 11 5 8 38 7 4 20 13 18 12 11 19 22 18 17 34 26 19 17 5 12 40 21 19 53 48 29 195 8 35 20 19 0 0 0 0 0 0 0 0 0 16 0 0 0 17 COG3340(Peptidase E) 55 80 93 65 4 13 19 14 5 7 7 7 6 20 14 7 6 16 13 30 31 23 66 40 36 14 21 12 22 11 31 32 24 17 70 70 17 34 16 26 9 7 0 0 0 2 0 1 1 0 0 16 1 0 0 9 COG1488(Nicotinic acid phosphoribosyltransferase) 146 26 37 33 11 14 23 6 3 11 6 5 4 25 4 5 24 19 25 18 23 12 30 11 7 24 20 18 18 6 14 34 32 25 63 45 13 195 12 41 4 17 0 0 0 0 0 0 0 0 0 9 2 0 0 15 COG0295(Cytidine deaminase) 114 22 49 20 2 8 9 21 9 1 6 3 13 20 10 11 25 32 12 15 11 18 24 13 12 89 25 17 19 3 19 31 31 16 34 65 16 171 30 25 12 15 0 0 0 0 0 1 0 0 0 15 0 0 0 20 COG0327(Uncharacterized conserved protein) 117 26 14 16 10 3 27 17 5 5 5 14 5 18 19 13 24 28 23 19 10 12 31 15 16 25 15 14 9 2 15 17 14 16 48 61 28 304 9 18 11 6 0 0 0 0 0 0 0 0 0 7 0 0 0 22 COG2838(Monomeric isocitrate dehydrogenase) 164 21 45 31 17 6 9 19 14 19 16 6 11 42 8 15 20 25 38 26 11 20 35 5 23 5 29 12 15 8 6 33 17 14 56 62 37 76 12 59 7 10 0 0 0 2 0 0 0 0 0 13 0 0 0 12 COG1785(Alkaline phosphatase) 342 61 40 32 5 8 19 10 9 4 8 20 11 21 12 12 2 2 9 19 12 13 33 9 14 6 13 8 7 6 4 17 22 2 62 51 12 143 13 10 9 4 0 0 0 0 0 0 0 0 0 4 0 0 0 8 COG5564(Predicted TIM-barrel enzyme, possibly a dioxygenase) 516 23 23 21 1 5 4 12 1 7 13 4 3 19 9 1 10 10 12 5 2 6 6 1 2 32 2 5 5 3 4 24 17 6 30 22 30 186 14 18 2 2 0 0 0 0 0 0 0 2 0 2 0 0 0 4 NOG07592() 16 42 37 42 14 2 13 33 12 8 12 3 11 19 14 13 26 31 36 10 9 16 23 19 19 88 11 8 15 3 9 32 30 30 82 67 8 197 9 23 10 8 0 0 0 0 0 0 1 0 0 8 0 0 0 6 COG2717(Predicted membrane protein) 144 39 56 42 7 2 9 26 19 17 3 13 8 23 20 24 29 21 16 38 10 6 23 7 12 42 30 19 11 0 9 36 37 32 84 64 25 30 17 24 12 13 0 0 0 0 0 0 0 0 0 5 0 0 0 20 COG2351(Transthyretin-like protein) 102 67 49 61 0 6 21 17 4 8 9 7 3 19 9 9 8 6 22 17 21 21 32 22 24 7 20 21 18 3 17 32 46 27 82 130 15 14 33 36 14 7 2 0 0 0 0 0 0 0 0 12 0 0 0 23 COG3378(Predicted ATPase) 51 25 31 29 6 8 10 43 25 6 16 10 18 31 14 21 17 29 27 23 20 12 38 15 21 43 16 7 5 16 18 6 9 12 18 39 27 313 16 1 0 6 0 2 0 0 0 0 0 0 2 5 0 0 0 15 COG2131(Deoxycytidylate deaminase) 49 15 60 17 8 4 19 21 24 6 28 10 26 25 15 9 18 20 19 54 16 22 45 15 22 108 19 7 8 12 12 26 25 20 60 86 31 53 9 23 11 9 0 0 0 0 0 0 0 0 0 7 0 0 0 28 NOG20191() 44 53 93 72 5 7 24 9 3 6 0 5 5 15 24 10 11 5 9 16 45 37 40 26 29 62 8 15 39 8 16 38 21 15 49 77 45 17 27 26 10 22 0 0 0 2 0 0 0 0 0 6 0 0 0 24 COG4107(ABC-type phosphonate transport system, ATPase component) 236 32 31 43 3 23 35 2 2 2 4 9 9 9 0 6 4 18 6 10 14 18 31 17 13 56 8 9 5 5 5 25 21 8 51 46 3 225 27 20 5 9 0 0 0 0 0 0 0 0 0 2 0 0 0 13 COG1189(Predicted rRNA methylase) 59 31 41 40 5 12 18 8 2 4 9 3 4 18 4 2 43 34 7 7 46 16 45 24 30 92 13 23 24 18 18 21 21 15 50 40 19 184 22 9 11 7 0 0 0 0 0 0 0 0 0 7 1 0 0 12 COG0083(Homoserine kinase) 66 29 33 31 10 12 12 18 6 3 6 1 2 7 10 2 41 49 13 15 31 11 37 31 27 131 6 28 26 19 24 19 15 7 42 34 8 190 15 26 7 0 0 0 0 0 0 0 0 0 0 5 0 0 0 13 NOG23282() 63 63 35 64 0 4 16 18 8 5 1 16 0 4 8 12 9 18 15 21 24 16 40 21 36 20 15 32 29 0 25 38 48 16 116 123 17 0 25 29 19 15 0 0 0 0 0 0 0 0 0 10 0 0 0 23 COG1592(Rubrerythrin) 75 52 35 46 2 0 15 20 7 11 7 17 19 18 28 32 24 15 30 28 20 16 22 22 17 18 29 15 12 0 11 29 28 27 78 65 38 101 31 17 11 4 1 0 0 0 0 0 0 0 0 0 0 0 0 22 COG3329(Predicted permease) 57 17 14 28 0 4 6 1 4 2 4 7 0 4 16 11 45 51 14 18 34 13 57 13 28 111 9 35 32 12 19 21 17 7 13 17 9 318 15 7 4 3 0 0 0 0 0 0 0 0 0 2 0 1 0 15 COG4733(Phage-related protein, tail component) 128 9 14 9 9 2 9 48 5 13 102 4 15 7 4 8 23 17 23 3 3 4 18 12 12 16 32 20 17 46 13 8 13 6 4 16 4 366 16 2 5 12 0 0 0 0 0 0 1 0 0 4 0 0 0 9 COG3829(Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains) 475 24 29 13 1 2 2 4 9 4 18 17 9 17 11 20 7 5 8 27 8 8 17 9 10 35 13 15 8 5 9 21 23 8 53 32 42 47 13 5 11 0 0 0 0 0 0 0 0 0 0 2 0 0 0 13 COG1025(Secreted/periplasmic Zn-dependent peptidases, insulinase-like) 181 39 69 32 5 13 13 6 5 11 10 8 2 9 8 9 10 6 16 19 14 22 26 18 14 13 28 11 10 1 7 22 11 18 25 39 40 271 19 7 3 4 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG1373(Predicted ATPase (AAA+ superfamily)) 47 8 2 5 3 3 0 0 2 0 4 3 0 14 5 3 33 17 8 1 0 1 2 1 0 47 2 0 0 0 0 0 0 0 4 0 158 726 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06372() 51 71 56 77 0 7 27 33 21 6 0 8 1 33 10 6 5 6 8 28 17 4 30 14 24 12 16 28 5 0 21 37 22 21 47 245 6 6 22 34 6 9 0 0 0 0 0 0 0 0 0 14 0 0 0 5 COG0615(Cytidylyltransferase) 76 41 76 31 8 6 10 31 9 15 9 7 19 29 18 12 16 19 16 24 15 21 34 17 15 45 21 20 17 27 10 27 33 24 40 68 29 90 16 14 11 7 0 0 0 0 0 0 0 0 2 2 0 0 0 22 COG3710(DNA-binding winged-HTH domains) 598 27 45 24 2 7 3 7 4 9 2 1 0 4 4 0 0 0 0 21 13 11 22 8 12 7 18 15 4 4 5 12 10 15 39 25 7 57 19 18 3 9 0 0 0 0 0 2 0 0 0 4 0 0 0 0 COG2189(Adenine specific DNA methylase Mod) 93 33 28 28 5 5 8 11 3 4 2 4 4 5 14 16 35 23 15 14 15 20 21 20 29 56 11 27 10 9 19 18 29 30 42 46 27 220 15 27 18 10 0 0 0 0 0 0 0 0 0 6 0 0 0 22 COG1722(Exonuclease VII small subunit) 73 46 72 43 3 9 10 17 8 8 6 4 3 16 5 4 26 34 19 20 7 8 35 13 24 63 13 15 7 6 11 37 25 21 76 52 19 161 15 19 8 13 0 0 0 0 0 0 0 0 0 11 1 0 0 10 COG0214(Pyridoxine biosynthesis enzyme) 9 25 85 16 0 1 10 4 5 0 1 9 3 25 14 10 32 50 11 22 20 20 39 24 24 122 21 24 24 9 15 31 32 22 9 64 6 154 10 16 21 14 0 0 0 0 0 0 0 0 0 13 0 0 0 29 COG3182(Uncharacterized iron-regulated membrane protein) 734 43 9 3 0 4 1 4 0 0 2 1 0 15 2 4 2 3 4 9 2 12 14 6 9 10 11 1 9 4 10 14 18 2 14 11 4 14 18 32 6 2 0 0 0 2 2 1 0 0 0 15 0 0 0 9 COG0378(Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase) 168 48 42 69 6 19 8 13 3 3 3 0 6 11 12 4 4 7 9 11 34 27 56 44 35 18 22 12 26 25 28 13 14 13 49 9 16 146 30 6 1 4 0 0 0 0 0 0 0 0 0 2 0 0 0 13 COG0502(Biotin synthase and related enzymes) 194 34 71 58 2 5 7 6 4 6 10 3 12 16 9 8 16 16 13 12 35 17 52 24 25 37 8 8 21 9 25 22 12 5 8 53 38 118 36 6 6 7 0 0 0 0 0 0 0 0 0 4 0 0 0 11 COG2603(Predicted ATPase) 154 22 40 29 5 3 8 17 2 15 5 9 8 34 8 5 10 8 25 7 31 16 49 28 36 5 16 18 11 19 27 33 24 15 51 37 8 186 19 13 9 8 0 1 0 0 0 0 0 0 0 9 0 0 0 5 COG4935(Regulatory P domain of the subtilisin-like proprotein convertases and other proteases) 240 15 31 22 0 1 5 6 2 7 6 4 2 28 13 3 7 10 6 28 15 30 34 14 21 19 8 12 13 9 13 33 27 13 37 46 17 157 36 31 21 8 0 2 0 0 0 0 0 0 0 7 0 0 0 28 COG1232(Protoporphyrinogen oxidase) 31 16 72 33 5 8 19 7 2 2 11 6 6 13 6 4 31 29 12 32 22 17 38 18 23 53 26 26 24 7 14 33 31 15 73 116 31 51 19 28 18 22 0 0 0 0 0 0 0 0 2 12 0 0 0 21 COG1448(Aspartate/tyrosine/aromatic aminotransferase) 284 18 11 16 8 13 4 13 3 10 10 7 14 44 6 7 13 13 24 15 8 19 11 10 10 40 16 9 14 5 18 16 29 11 40 44 11 150 17 17 7 13 0 0 0 0 0 0 1 0 0 13 0 0 0 23 COG3938(Proline racemase) 131 43 65 30 4 2 1 9 7 8 11 11 7 40 4 8 10 17 19 11 11 16 25 13 13 53 15 17 18 0 10 27 18 29 49 86 16 149 19 23 10 9 0 0 0 0 0 0 0 0 0 9 0 0 0 12 NOG10886() 31 56 82 64 0 0 2 21 9 7 5 26 6 4 18 25 29 12 15 23 12 13 15 13 7 27 17 24 13 0 9 36 31 50 105 132 20 1 30 36 17 9 0 1 0 0 0 0 0 1 0 2 0 0 0 29 COG3322(Predicted periplasmic ligand-binding sensor domain) 692 25 10 13 2 3 0 0 0 0 12 0 0 10 0 0 19 9 0 3 3 2 6 11 13 16 6 0 5 2 4 7 4 0 12 9 13 174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1377(Flagellar biosynthesis pathway, component FlhB) 141 24 25 24 10 19 12 14 8 8 17 14 8 28 4 8 7 13 13 12 16 16 38 20 20 14 17 13 11 3 12 33 27 13 57 23 25 230 25 21 6 13 0 0 1 0 0 0 0 0 0 9 0 0 0 11 COG1026(Predicted Zn-dependent peptidases, insulinase-like) 28 90 75 73 15 6 21 19 8 18 12 16 8 32 14 14 5 4 21 16 29 10 44 22 30 2 18 8 26 15 15 24 33 18 71 58 43 27 6 22 7 17 0 1 0 1 0 0 0 0 0 19 0 0 0 20 COG1492(Cobyric acid synthase) 294 23 24 50 4 14 10 5 3 6 2 10 7 19 6 1 3 2 7 5 26 32 52 30 47 13 9 19 21 14 30 35 15 18 33 19 8 66 38 23 4 11 0 0 0 0 0 0 0 1 0 13 0 0 0 8 COG3194(Ureidoglycolate hydrolase) 176 54 41 49 2 7 4 10 4 5 9 11 7 17 14 15 17 12 17 19 23 15 25 7 9 3 20 16 7 2 9 30 33 40 71 137 22 25 33 22 17 6 0 0 0 0 0 0 0 0 0 7 0 0 0 8 COG1682(ABC-type polysaccharide/polyol phosphate export systems, permease component) 118 12 27 12 3 6 5 10 2 8 4 0 0 12 7 8 41 56 13 14 3 11 20 12 16 103 11 14 2 9 4 31 7 14 22 21 12 343 15 16 10 3 0 0 2 0 0 0 0 0 0 5 0 0 0 13 NOG14558() 4 28 43 22 7 1 10 10 41 5 14 9 20 15 10 4 10 8 14 16 24 25 45 14 12 60 25 32 24 6 16 57 41 24 87 80 4 31 26 66 20 12 0 0 0 0 6 0 0 2 0 14 0 0 0 32 COG2193(Bacterioferritin (cytochrome b1)) 142 63 101 56 3 2 22 9 8 9 3 7 9 12 12 16 3 5 11 22 14 17 34 23 17 2 20 20 11 4 14 35 16 10 62 75 29 94 11 30 9 4 0 0 0 1 0 0 0 2 0 0 0 0 0 7 COG0835(Chemotaxis signal transduction protein) 579 29 17 9 1 1 2 1 1 0 7 5 3 8 2 2 5 4 5 1 6 9 9 4 2 8 15 6 5 5 8 14 8 10 21 14 64 135 16 22 1 8 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG06245() 15 20 48 13 31 6 17 10 21 9 18 9 8 22 20 11 19 10 19 11 12 23 25 18 30 105 16 26 8 3 6 25 38 26 101 84 13 37 17 50 15 30 0 0 0 0 1 1 0 2 0 10 0 0 0 16 COG0428(Predicted divalent heavy-metal cations transporter) 64 22 33 30 19 6 21 4 10 9 5 7 9 31 10 16 23 28 11 8 8 11 23 8 6 16 14 19 15 2 13 30 31 25 79 56 49 204 12 38 16 12 0 0 0 0 0 0 0 0 0 7 0 0 0 13 COG1047(FKBP-type peptidyl-prolyl cis-trans isomerases 2) 197 25 33 21 5 2 0 19 6 8 19 11 6 38 29 9 19 19 25 12 17 21 31 11 14 46 6 9 14 9 7 14 14 2 8 45 67 169 6 9 15 7 0 0 0 0 0 0 0 0 0 1 0 0 0 26 COG1349(Transcriptional regulators of sugar metabolism) 344 11 7 8 2 5 2 8 10 2 4 7 12 30 5 5 14 20 29 2 3 0 3 7 4 38 12 2 2 5 7 17 17 18 31 14 24 279 17 17 7 8 0 0 0 0 0 0 0 0 0 1 0 0 0 9 COG2333(Predicted hydrolase (metallo-beta-lactamase superfamily)) 186 5 1 2 4 1 1 16 5 7 18 1 4 32 12 10 35 42 32 2 2 3 5 2 0 116 2 0 0 1 0 2 0 0 6 1 61 443 2 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3195(Uncharacterized protein conserved in bacteria) 168 46 40 52 1 9 8 14 5 5 9 2 2 20 5 11 11 8 28 12 11 20 27 14 17 12 28 20 20 5 8 31 34 11 79 114 25 42 20 19 13 17 1 0 0 0 0 0 0 0 0 5 0 0 0 18 COG4239(ABC-type uncharacterized transport system, permease component) 163 36 47 37 0 5 7 14 2 9 2 6 9 25 2 8 10 9 14 13 22 21 23 22 20 12 12 23 14 4 5 38 14 15 39 51 22 184 17 38 11 12 0 1 0 0 0 0 0 0 0 15 0 0 0 13 COG5012(Predicted cobalamin binding protein) 25 26 59 27 9 7 5 9 10 10 13 4 13 37 9 8 29 49 14 20 27 14 27 13 25 71 22 17 15 6 13 29 18 38 45 49 26 148 20 29 9 5 0 0 0 0 2 0 0 0 0 7 0 0 0 8 COG1544(Ribosome-associated protein Y (PSrp-1)) 171 10 6 18 3 11 1 11 4 9 7 5 11 25 5 4 33 20 17 12 22 14 34 18 11 31 9 14 14 10 16 33 12 7 49 35 31 254 27 8 6 12 0 0 0 0 0 0 1 0 0 5 0 0 1 7 COG5557(Polysulphide reductase) 27 43 61 53 14 6 16 25 16 12 7 13 6 15 6 10 8 26 9 17 12 21 62 14 17 10 20 18 10 2 15 38 34 27 88 66 20 78 18 32 29 10 2 0 0 0 2 0 0 0 0 9 1 0 0 18 COG3616(Predicted amino acid aldolase or racemase) 159 39 42 30 4 10 7 8 14 8 11 7 4 30 12 3 24 14 13 11 17 14 33 16 13 68 23 24 13 4 17 35 23 24 63 60 5 39 19 51 8 12 0 0 0 0 0 2 0 0 0 12 1 0 0 15 COG4136(ABC-type uncharacterized transport system, ATPase component) 123 47 34 41 3 6 13 12 10 8 6 12 8 17 12 12 13 22 16 19 22 23 29 18 26 25 25 19 16 2 17 28 27 22 73 58 15 80 28 19 13 10 0 0 0 1 0 0 1 0 0 9 0 1 0 19 COG2815(Uncharacterized protein conserved in bacteria) 8 17 28 10 0 0 9 2 1 0 2 0 2 3 2 7 44 87 9 5 14 6 16 6 8 210 10 6 5 0 8 8 15 8 14 75 6 353 10 5 4 11 0 0 0 0 0 0 0 0 0 9 0 0 0 17 COG4096(Type I site-specific restriction-modification system, R (restriction) subunit and related helicases) 112 43 47 30 2 4 7 18 2 9 7 10 1 15 7 7 9 22 13 9 7 18 35 12 14 40 18 19 19 7 14 27 17 14 28 42 17 269 16 19 2 4 2 0 0 0 0 0 0 0 0 5 0 0 0 20 COG1994(Zn-dependent proteases) 167 29 63 41 10 5 2 4 2 2 3 8 10 29 7 7 30 16 11 8 30 21 48 19 53 45 13 24 24 18 26 18 6 0 8 27 47 101 19 11 9 8 0 0 0 0 0 0 0 0 0 2 0 0 0 20 COG2268(Uncharacterized protein conserved in bacteria) 175 42 33 16 5 5 16 26 12 3 3 8 9 29 14 6 15 3 19 23 18 22 36 7 10 22 13 10 10 5 10 37 21 10 59 144 10 51 31 13 12 17 0 0 0 0 0 0 0 0 0 13 0 0 0 8 COG2515(1-aminocyclopropane-1-carboxylate deaminase) 145 33 48 43 18 5 10 8 15 18 24 5 6 50 12 15 9 11 23 7 6 10 21 13 14 30 21 15 17 6 1 38 25 17 28 80 25 77 20 35 12 4 0 0 0 0 0 0 0 0 0 16 0 0 0 14 COG2038(NaMN:DMB phosphoribosyltransferase) 174 27 34 62 6 9 9 2 2 6 3 3 11 15 2 9 1 4 3 15 40 19 49 38 25 23 9 25 21 29 25 27 20 10 34 21 5 134 41 22 5 5 2 0 0 0 0 0 0 0 0 14 0 0 0 7 NOG14015() 9 16 14 6 2 1 7 64 8 30 73 7 18 26 19 22 11 13 112 14 10 16 26 13 6 17 28 7 17 26 8 35 40 8 10 10 10 238 3 13 4 8 0 0 0 0 0 0 0 0 0 11 0 0 0 10 COG3011(Uncharacterized protein conserved in bacteria) 104 34 28 35 10 6 9 10 5 10 12 4 6 11 12 17 8 5 12 21 25 34 47 22 32 31 13 26 27 14 22 27 30 18 74 35 14 87 32 23 13 8 1 0 1 1 0 0 0 0 0 12 0 0 0 15 COG3225(ABC-type uncharacterized transport system involved in gliding motility, auxiliary component) 25 27 86 33 7 17 14 22 5 8 3 4 3 35 27 4 11 16 14 12 25 32 50 16 19 33 21 34 16 7 14 26 17 12 58 31 52 137 15 10 8 15 0 0 0 0 0 0 0 0 0 8 0 0 0 13 COG0655(Multimeric flavodoxin WrbA) 264 27 28 30 3 5 10 31 11 12 7 9 10 27 16 18 19 14 19 10 17 15 25 8 18 22 14 5 8 6 6 12 20 12 35 39 30 141 4 15 1 2 0 0 0 0 0 0 0 0 0 7 0 0 0 10 COG1912(Uncharacterized conserved protein) 116 13 34 20 16 1 25 11 8 10 7 4 6 24 18 15 13 19 6 22 24 14 34 13 25 44 21 36 16 4 20 37 38 18 54 95 13 43 16 24 17 7 0 0 0 0 0 0 0 0 0 9 1 0 0 25 NOG36034() 93 8 25 9 0 5 0 5 3 3 3 0 0 10 0 0 58 27 1 0 6 4 5 1 0 81 3 4 0 1 0 0 3 0 4 0 14 657 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1706(Flagellar basal-body P-ring protein) 166 26 25 23 6 8 18 18 3 0 2 2 7 36 12 7 16 17 26 9 14 20 20 6 14 16 20 8 16 11 11 25 27 4 53 35 22 194 19 28 5 14 0 0 0 0 0 0 0 0 0 17 2 0 1 6 COG0819(Putative transcription activator) 44 42 28 64 2 15 24 16 10 8 3 10 8 7 9 30 25 26 11 13 44 21 51 28 32 2 19 27 28 8 33 37 30 16 70 58 16 12 23 29 8 13 0 0 2 0 3 0 0 0 0 13 1 0 0 13 COG0627(Predicted esterase) 207 28 53 27 10 11 9 20 7 20 5 4 7 16 11 8 3 3 19 16 16 6 11 7 10 4 11 15 11 7 3 31 35 22 43 48 12 172 20 27 10 5 0 0 0 1 0 0 0 0 0 4 0 0 0 16 COG4188(Predicted dienelactone hydrolase) 96 27 70 28 9 4 6 10 14 3 2 7 4 18 15 17 11 2 22 18 38 18 41 29 35 20 22 15 18 29 29 29 19 14 30 41 5 126 49 6 9 2 0 0 0 0 0 0 0 0 0 11 0 0 0 11 COG3622(Hydroxypyruvate isomerase) 119 19 45 35 6 21 12 14 9 17 6 9 4 41 8 9 32 16 21 10 16 14 28 16 7 15 32 15 7 6 3 28 21 24 57 48 31 124 16 25 9 7 0 0 0 0 0 0 0 0 0 12 0 0 0 15 NOG19707(Phytanoyl-Coa dioxygenase) 43 42 59 48 7 10 9 8 9 8 2 15 6 28 29 23 22 24 26 24 25 10 31 12 23 40 42 22 9 2 12 31 26 23 68 74 10 27 19 29 10 16 0 0 0 0 0 0 0 0 0 7 0 0 0 18 COG3455(Uncharacterized protein conserved in bacteria) 294 13 17 14 7 1 5 16 7 11 14 2 6 37 4 8 3 1 13 8 10 9 18 16 7 8 9 19 11 3 3 30 17 21 59 30 21 174 4 43 5 7 0 0 0 0 0 0 0 0 0 10 0 0 0 9 COG3211(Predicted phosphatase) 132 59 84 46 8 8 4 12 4 5 1 4 7 19 2 10 16 18 10 18 22 29 32 25 20 66 7 5 6 2 7 11 9 2 21 35 14 236 0 2 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG1405(Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB) 1 32 91 34 7 1 1 36 36 9 4 18 36 21 17 18 31 38 17 48 26 28 33 7 10 61 23 16 14 8 6 16 37 14 15 68 49 3 13 19 16 10 0 0 1 0 0 0 0 0 0 4 0 0 0 26 COG1408(Predicted phosphohydrolases) 65 15 26 14 4 3 11 11 16 5 9 14 4 24 10 3 15 37 10 5 12 17 24 11 5 76 12 10 8 3 12 27 14 20 55 36 13 296 5 22 17 8 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG1449(Alpha-amylase/alpha-mannosidase) 26 11 13 9 0 0 17 2 5 0 0 0 4 30 4 19 40 16 9 24 19 33 36 31 22 0 50 30 23 5 16 53 50 30 38 48 49 78 33 21 31 9 1 2 0 0 0 0 0 0 0 15 0 0 0 64 COG2153(Predicted acyltransferase) 120 56 54 31 10 5 25 17 6 12 4 6 9 15 6 10 0 8 25 17 11 15 34 12 8 7 24 15 18 5 10 35 22 11 106 67 14 76 19 28 16 14 0 0 0 1 0 1 0 0 0 3 0 0 0 7 COG4170(ABC-type antimicrobial peptide transport system, ATPase component) 265 35 24 34 1 4 7 12 8 2 10 4 7 19 11 11 4 4 15 17 4 12 24 9 14 21 7 16 13 2 17 21 14 15 22 54 14 148 24 24 2 14 2 0 0 0 0 0 0 0 0 9 0 0 0 17 COG0448(ADP-glucose pyrophosphorylase) 120 25 20 33 10 6 2 14 1 3 4 0 1 5 0 2 38 18 6 12 35 9 34 18 31 84 10 15 12 16 22 16 2 5 12 11 13 299 22 7 4 4 0 0 0 0 0 0 0 0 0 7 0 0 0 1 COG1348(Nitrogenase subunit NifH (ATPase)) 47 19 8 36 4 6 4 18 8 5 4 0 5 20 2 1 7 10 9 13 24 25 40 19 16 27 22 28 28 18 26 32 27 16 72 25 9 214 31 32 14 10 0 0 0 0 0 0 0 0 0 14 0 0 0 11 COG1451(Predicted metal-dependent hydrolase) 142 18 27 26 3 6 1 5 10 8 14 9 6 28 11 8 50 45 12 15 12 11 19 8 11 94 6 13 12 3 15 24 12 4 38 49 47 130 9 12 4 12 0 0 0 0 0 0 0 0 0 8 0 0 0 9 COG1277(ABC-type transport system involved in multi-copper enzyme maturation, permease component) 62 20 73 37 7 9 12 24 4 8 8 7 9 19 6 7 14 23 12 15 20 12 30 11 9 34 17 30 13 3 18 22 12 8 35 48 34 211 10 24 5 15 0 0 0 0 0 0 0 0 0 5 0 0 0 2 NOG05375(Indoleamine-Pyrrole 2,3 dioxygenase) 25 62 61 29 4 1 14 17 5 1 0 9 2 6 2 18 19 24 19 27 20 27 44 23 26 95 19 20 18 11 12 35 30 29 54 75 18 3 19 19 9 8 0 0 0 0 0 2 0 0 0 7 0 0 0 35 COG4590(ABC-type uncharacterized transport system, permease component) 133 73 50 75 0 4 16 4 2 7 7 10 0 10 4 16 38 48 17 32 29 43 60 39 31 26 17 13 10 0 2 0 7 4 21 4 0 138 2 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 7 COG3336(Predicted membrane protein) 58 11 17 14 0 2 7 6 6 0 5 3 4 17 2 10 45 45 17 16 11 15 13 11 11 177 22 8 4 0 2 20 8 7 21 35 0 285 16 1 9 4 0 0 0 0 0 0 0 0 0 8 0 0 0 28 COG2834(Outer membrane lipoprotein-sorting protein) 103 46 29 39 3 9 8 26 5 6 14 6 5 22 6 17 23 19 13 17 18 23 21 12 21 12 23 14 22 4 10 27 18 11 58 57 24 134 15 23 6 10 0 0 0 0 0 0 0 0 0 7 0 0 0 14 COG2246(Predicted membrane protein) 153 24 50 37 7 5 11 5 2 0 5 5 0 9 2 2 16 8 3 20 16 26 25 20 8 43 17 18 14 3 21 28 15 9 27 50 29 185 13 24 10 11 0 0 0 0 0 0 0 0 0 9 0 0 0 15 COG3537(Putative alpha-1,2-mannosidase) 332 2 21 6 9 4 5 14 10 11 20 15 8 11 6 4 1 13 5 16 3 14 13 4 2 6 14 12 0 2 6 32 43 32 69 63 6 38 12 57 28 18 0 0 0 0 0 0 0 0 0 3 0 0 0 8 COG2730(Endoglucanase) 120 11 75 20 30 7 14 9 7 12 6 6 8 2 11 2 11 17 8 13 12 36 41 12 23 23 26 12 15 16 15 13 11 14 55 31 30 144 10 44 5 8 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG1648(Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)) 156 39 23 23 3 7 2 22 2 20 17 10 11 48 8 15 16 32 39 18 8 3 11 4 6 36 19 7 6 1 4 14 3 10 17 34 22 208 31 11 4 8 0 0 0 0 0 0 0 0 0 2 0 0 0 10 COG1402(Uncharacterized protein, putative amidase) 105 35 43 35 9 14 9 5 2 5 0 4 6 11 16 2 14 16 6 20 22 22 42 22 17 48 28 8 17 33 13 27 10 26 25 42 19 135 39 15 6 4 0 0 0 0 0 1 0 0 0 6 0 0 1 4 COG3608(Predicted deacylase) 263 29 35 18 4 2 1 1 4 2 5 11 1 11 3 12 4 6 12 12 12 25 26 8 17 17 25 12 5 13 5 18 21 7 10 32 36 210 1 14 11 4 0 0 0 0 0 0 0 0 0 7 0 0 0 17 COG1118(ABC-type sulfate/molybdate transport systems, ATPase component) 302 22 24 20 1 0 4 4 2 0 4 0 0 10 2 1 20 14 9 13 16 12 20 9 14 31 22 17 7 1 12 16 24 13 30 38 10 184 13 13 9 9 0 0 0 1 0 0 0 0 0 3 0 0 0 13 COG2913(Small protein A (tmRNA-binding)) 101 59 64 34 5 4 19 7 9 9 13 14 10 30 6 6 15 14 13 23 15 9 19 14 15 14 23 7 11 3 5 35 25 12 69 52 20 119 8 20 11 12 0 0 0 0 0 0 0 0 0 5 0 0 0 10 COG0370(Fe2+ transport system protein B) 94 18 27 13 24 3 12 17 18 23 17 19 13 23 8 9 18 14 17 14 8 16 16 13 13 75 7 8 8 6 7 20 24 15 17 47 42 195 8 21 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 12 COG2222(Predicted phosphosugar isomerases) 131 52 29 24 1 2 8 12 4 5 4 5 3 11 6 4 27 51 5 23 16 8 14 20 18 55 7 23 6 5 28 24 12 20 48 65 16 101 30 26 9 10 0 0 0 0 0 0 2 0 0 6 0 0 0 7 COG0252(L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D) 124 19 66 14 8 8 1 11 11 3 9 10 5 23 15 4 16 14 10 18 10 15 26 8 7 31 11 7 10 8 5 43 35 9 37 38 83 87 37 40 12 13 0 0 0 0 0 1 0 0 0 6 0 0 0 13 NOG11257() 39 99 120 77 0 4 25 15 7 13 4 5 10 15 7 5 6 1 11 17 19 18 51 17 19 0 12 6 19 9 5 36 29 19 100 50 7 19 23 19 3 12 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG1486(Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases) 51 64 51 51 7 6 15 6 0 0 0 2 2 1 4 3 5 11 4 25 27 15 42 18 32 3 18 20 13 2 15 38 24 26 78 83 6 70 24 24 16 26 0 0 0 0 0 0 0 0 0 24 0 0 0 24 NOG17855() 41 57 40 66 0 8 17 19 7 8 4 13 2 10 24 21 9 18 13 30 17 17 20 25 33 13 23 20 20 1 13 39 22 29 72 110 9 2 30 19 5 10 0 0 0 0 0 0 0 0 0 8 0 0 0 11 COG3830(ACT domain-containing protein) 108 14 5 10 3 5 7 13 1 4 9 6 10 36 13 9 52 41 34 8 19 3 11 7 18 77 17 4 16 1 6 21 10 4 32 29 30 212 15 17 9 12 0 0 0 0 0 0 0 0 0 4 0 0 0 12 COG4274(Uncharacterized conserved protein) 38 63 44 59 2 2 15 15 7 3 1 6 2 5 5 13 9 7 6 29 39 6 38 33 23 0 20 35 18 0 23 32 36 22 80 106 19 0 22 31 14 6 0 0 0 0 2 0 0 0 0 17 0 0 0 19 COG0725(ABC-type molybdate transport system, periplasmic component) 240 9 22 11 3 13 2 6 4 0 13 5 8 22 4 4 33 17 11 4 18 6 13 8 6 60 5 1 6 4 8 8 9 8 10 21 31 297 5 4 3 3 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG3152(Predicted membrane protein) 67 46 40 54 7 1 7 4 4 6 5 6 6 17 7 8 12 20 14 15 21 18 44 16 17 63 16 11 10 5 14 24 16 23 32 62 6 179 3 12 5 3 0 1 0 1 2 0 0 0 0 11 0 0 0 9 COG5245(Dynein, heavy chain) 2 61 109 74 87 175 0 6 2 18 4 0 5 8 0 0 6 4 51 22 19 7 10 6 0 2 12 11 4 180 6 17 0 0 4 4 10 28 4 2 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG3427(Uncharacterized conserved protein) 86 36 46 55 2 10 5 11 2 2 5 1 3 20 17 9 32 35 16 31 14 14 17 13 14 38 18 16 8 0 7 26 14 20 43 100 14 106 11 20 9 7 0 0 0 0 0 0 0 0 0 4 0 0 0 11 COG1850(Ribulose 1,5-bisphosphate carboxylase, large subunit) 31 16 15 34 9 9 3 1 1 3 2 2 0 18 1 5 10 8 8 7 27 14 45 27 26 33 5 9 24 34 33 30 14 4 19 39 22 338 20 7 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 2 COG1478(Uncharacterized conserved protein) 20 65 66 35 2 5 17 10 4 4 3 12 9 19 20 13 15 6 12 16 19 19 21 16 26 66 12 25 11 1 8 26 16 21 32 56 14 133 17 30 12 7 0 0 0 0 0 0 0 0 0 11 0 0 0 15 COG1783(Phage terminase large subunit) 11 7 6 10 1 3 2 65 12 32 97 6 18 15 4 15 7 17 93 3 7 14 22 15 10 7 24 6 6 21 0 41 39 8 12 10 8 268 2 3 3 0 0 0 0 0 0 0 1 1 0 6 0 0 0 8 COG4148(ABC-type molybdate transport system, ATPase component) 72 22 25 19 2 5 9 24 9 15 8 16 7 39 9 12 11 13 22 22 8 22 17 10 18 16 19 14 8 6 9 24 16 16 37 47 25 228 11 14 6 6 0 0 0 0 0 0 0 0 0 7 0 0 0 20 COG1363(Cellulase M and related proteins) 22 25 40 24 21 8 10 15 20 15 2 3 11 15 4 16 19 3 13 23 16 17 25 8 16 24 19 17 9 5 5 37 33 25 75 86 12 130 20 33 13 7 0 0 1 0 0 0 0 1 0 11 0 0 0 9 COG2511(Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain)) 25 49 73 48 0 1 7 5 0 0 0 2 4 12 6 13 32 10 3 23 14 34 35 21 8 45 23 25 10 6 9 32 56 48 45 60 65 29 17 11 18 4 0 0 0 0 0 0 0 0 0 11 0 0 0 23 NOG06130() 18 31 85 36 10 2 31 12 27 6 9 4 7 10 12 4 6 11 6 12 16 38 31 16 21 15 12 23 13 1 12 40 30 21 89 92 6 42 11 42 14 9 0 5 0 1 0 0 0 0 2 9 0 0 0 12 COG2172(Anti-sigma regulatory factor (Ser/Thr protein kinase)) 95 9 11 25 3 3 1 0 2 3 10 2 5 16 2 7 7 0 11 14 17 10 31 19 23 3 14 15 14 10 29 22 9 1 21 15 19 409 26 7 3 6 0 0 0 0 0 1 0 0 0 3 0 0 0 8 COG4196(Uncharacterized protein conserved in bacteria) 294 38 20 22 4 9 11 8 0 0 2 0 6 9 0 4 12 12 0 8 22 12 24 10 17 15 8 3 12 17 15 1 0 0 1 2 10 316 13 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG2365(Protein tyrosine/serine phosphatase) 132 25 40 19 3 6 11 20 0 9 6 3 0 24 3 4 11 13 19 14 8 13 25 10 9 24 6 14 15 0 5 33 27 12 60 51 5 220 8 18 7 7 0 0 0 0 0 0 0 0 0 3 0 0 0 18 COG1316(Transcriptional regulator) 41 8 15 10 5 1 10 3 4 0 0 2 0 5 4 5 49 63 10 10 14 9 28 6 3 162 18 6 9 4 9 24 14 20 18 40 18 221 50 5 5 5 0 0 0 0 0 0 0 0 0 7 0 0 0 19 COG3067(Na+/H+ antiporter) 77 64 61 36 6 12 24 11 11 17 7 11 4 31 11 6 4 0 12 12 6 11 42 18 27 0 24 22 27 14 10 38 20 17 94 28 21 33 27 14 9 3 0 0 0 0 0 0 0 0 0 18 1 0 0 14 COG2251(Predicted nuclease (RecB family)) 59 21 19 41 2 9 3 6 2 2 11 8 8 6 4 4 12 28 13 12 33 13 47 20 44 23 13 22 23 10 46 29 17 8 39 52 8 164 32 6 4 4 0 0 0 0 0 0 0 0 0 6 0 0 0 21 COG3502(Uncharacterized protein conserved in bacteria) 28 44 28 29 2 7 11 25 6 7 19 22 7 8 10 12 11 5 17 15 16 14 26 16 14 4 29 20 10 7 20 42 28 19 96 51 10 101 33 32 11 15 0 0 0 0 0 0 0 0 0 8 0 0 0 17 COG0729(Outer membrane protein) 349 7 14 5 13 0 2 1 0 0 15 1 4 8 4 0 14 6 11 3 5 9 9 5 2 15 9 4 7 0 5 5 1 2 6 13 9 376 3 6 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4972(Tfp pilus assembly protein, ATPase PilM) 91 30 60 24 0 5 6 20 12 7 8 11 11 21 2 9 23 5 19 20 18 19 31 24 30 44 17 13 20 3 13 15 7 6 37 64 63 105 0 5 2 4 0 0 0 0 0 2 0 0 0 12 0 0 0 13 COG2340(Uncharacterized protein with SCP/PR1 domains) 239 9 63 18 3 4 7 13 14 0 14 6 4 23 4 14 22 11 9 10 29 13 29 12 8 31 16 14 12 1 5 15 21 23 18 50 16 60 20 18 15 2 0 0 0 0 0 1 2 1 0 5 0 2 0 25 COG3511(Phospholipase C) 878 2 2 1 2 2 0 0 0 0 0 0 0 2 0 0 0 0 1 0 4 0 1 0 3 0 0 2 0 4 2 1 1 4 10 3 0 3 6 4 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG5013(Nitrate reductase alpha subunit) 303 42 119 54 0 0 3 8 3 8 11 3 4 29 6 8 29 24 7 21 7 10 22 11 4 13 11 4 1 1 9 3 12 0 14 35 8 63 14 7 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 11 COG1295(Predicted membrane protein) 215 28 12 23 15 7 7 5 5 10 10 5 4 16 11 10 13 15 14 6 21 13 28 21 20 26 10 19 22 22 22 25 8 18 26 13 17 134 13 14 7 6 0 0 0 0 0 0 0 0 0 6 0 0 0 6 COG1797(Cobyrinic acid a,c-diamide synthase) 117 34 43 46 7 10 8 5 6 4 0 7 4 5 5 2 6 0 9 13 44 13 41 33 44 16 14 7 25 19 36 39 15 18 21 37 13 95 39 13 3 10 0 0 0 2 0 0 0 0 0 6 0 0 0 13 COG2329(Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides) 51 17 20 27 5 6 7 10 6 4 5 11 3 16 7 8 19 24 18 7 14 13 29 14 15 22 14 22 18 5 17 43 31 36 98 55 9 76 37 28 16 24 0 0 0 0 1 0 0 1 0 21 0 0 0 15 COG2201(Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain) 344 38 25 14 3 4 5 2 0 0 5 4 0 12 2 4 16 4 4 6 4 5 8 12 7 12 13 5 3 1 2 14 2 2 9 7 87 231 4 4 0 8 0 0 0 0 0 0 0 0 0 5 0 0 0 8 COG1283(Na+/phosphate symporter) 27 14 90 16 1 3 0 11 13 5 5 11 9 31 18 19 12 8 25 29 19 13 23 11 8 14 49 28 23 3 12 33 30 22 24 77 37 60 10 15 22 15 0 0 0 0 0 0 0 0 0 17 1 0 0 31 COG3307(Lipid A core - O-antigen ligase and related enzymes) 237 23 22 22 4 7 3 4 1 1 0 3 0 8 8 5 12 8 8 5 23 10 24 22 16 14 5 15 14 21 13 37 5 3 20 15 45 190 46 6 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 COG2379(Putative glycerate kinase) 25 34 47 27 5 13 8 20 6 8 4 4 5 12 6 5 11 9 8 14 11 6 21 9 21 27 16 15 13 4 15 27 22 16 65 40 18 256 18 21 7 7 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG3039(Transposase and inactivated derivatives, IS5 family) 184 15 17 5 5 0 0 2 5 9 6 0 1 16 4 2 3 7 17 1 6 6 13 14 0 15 16 4 2 6 4 6 1 0 0 3 84 445 1 8 0 2 0 0 0 0 0 0 0 0 0 1 1 0 0 2 COG1762(Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)) 217 12 20 18 2 9 6 18 2 3 20 4 3 20 5 3 15 8 6 13 8 22 19 6 3 18 7 12 7 3 9 23 13 5 38 33 37 192 17 21 10 14 0 0 0 0 0 0 1 0 0 2 0 0 0 13 COG3590(Predicted metalloendopeptidase) 186 24 35 22 1 2 1 7 5 7 10 0 3 29 4 5 62 69 30 4 5 0 12 4 4 104 6 2 1 2 1 7 9 4 17 43 7 187 1 3 5 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG0455(ATPases involved in chromosome partitioning) 132 30 26 17 3 15 4 3 4 3 16 8 4 21 8 3 11 21 11 8 10 3 21 10 18 31 17 7 8 2 12 14 12 14 39 25 35 247 11 18 5 8 0 0 0 0 0 0 0 0 0 4 0 0 0 15 COG1765(Predicted redox protein, regulator of disulfide bond formation) 140 12 30 14 8 0 11 11 11 6 13 8 14 21 5 6 18 8 23 14 8 12 13 8 5 19 10 17 13 1 4 15 14 21 25 44 22 237 13 26 5 11 0 0 0 1 0 0 0 0 0 8 0 0 0 8 COG0426(Uncharacterized flavoproteins) 90 21 4 56 15 11 0 1 0 4 3 0 3 1 0 0 3 0 1 3 57 26 99 45 72 1 14 21 30 35 52 52 7 9 17 8 17 65 59 12 1 6 0 0 0 0 0 0 0 0 0 4 0 1 0 7 COG1624(Uncharacterized conserved protein) 20 19 55 34 11 8 16 12 4 3 1 5 5 9 5 13 6 6 14 12 39 30 51 28 47 8 29 17 26 13 24 26 10 15 60 41 24 88 29 27 15 8 0 0 0 0 0 0 0 0 0 6 0 0 0 13 COG2258(Uncharacterized protein conserved in bacteria) 169 36 39 32 4 3 6 16 6 5 4 3 6 14 9 12 19 17 7 13 11 22 30 12 11 26 31 15 7 4 4 23 28 31 70 68 10 33 15 21 5 7 0 0 0 0 0 0 0 0 0 5 0 0 0 23 COG3485(Protocatechuate 3,4-dioxygenase beta subunit) 319 26 27 29 3 12 6 16 4 4 3 3 1 32 3 10 17 2 8 14 18 13 23 15 7 12 23 9 7 3 11 14 12 1 27 30 10 120 11 8 6 2 0 0 0 0 0 0 0 0 0 5 0 0 0 5 COG3191(L-aminopeptidase/D-esterase) 187 24 68 26 5 5 8 8 5 5 6 1 7 29 8 5 7 1 10 24 10 14 16 6 17 36 22 3 13 0 8 19 29 8 42 67 11 94 14 15 16 16 0 0 0 0 0 0 0 0 0 8 0 0 0 6 NOG06500() 7 9 22 6 4 6 9 6 11 2 15 45 19 24 18 7 3 17 7 5 21 19 28 21 18 8 26 25 4 16 5 36 45 6 55 79 68 66 17 46 19 16 2 0 0 0 0 0 0 0 0 17 0 0 0 21 COG5059(Kinesin-like protein) 6 30 84 42 45 65 4 6 3 7 9 5 0 20 8 14 13 17 44 10 10 23 17 6 13 16 16 19 17 175 2 12 8 10 20 23 19 42 10 10 9 2 0 0 0 0 0 0 0 0 0 2 0 0 0 13 COG1293(Predicted RNA-binding protein homologous to eukaryotic snRNP) 40 32 44 41 4 8 2 5 2 5 0 9 6 5 4 8 8 8 8 11 50 50 62 22 48 28 7 22 26 20 18 31 29 4 5 21 32 83 35 23 13 17 0 0 2 0 0 0 0 0 0 4 0 1 0 22 COG0675(Transposase and inactivated derivatives) 571 3 1 1 2 2 0 10 2 0 4 2 2 8 0 1 19 26 1 0 3 0 8 1 0 23 0 0 0 0 1 1 0 0 0 0 67 161 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5412(Phage-related protein) 74 40 44 34 9 1 8 6 1 13 9 0 4 12 4 4 3 7 9 10 14 12 19 8 15 18 5 13 13 6 11 23 16 26 42 43 34 242 16 24 6 11 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1289(Predicted membrane protein) 842 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 0 0 1 0 0 4 2 2 4 0 3 0 0 0 0 0 0 46 3 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 COG3908(Uncharacterized protein conserved in bacteria) 58 49 37 60 2 2 11 16 4 4 6 10 1 0 10 6 14 17 12 20 22 21 34 20 28 9 21 12 26 1 23 39 24 26 85 79 16 2 13 28 15 7 0 0 0 0 2 0 0 0 0 5 0 0 0 21 COG2309(Leucyl aminopeptidase (aminopeptidase T)) 28 29 37 37 5 8 14 7 8 3 1 4 4 23 9 3 3 4 10 25 33 33 33 26 24 12 24 16 19 3 20 42 27 23 34 51 25 79 16 32 20 7 0 0 0 0 0 0 0 0 0 16 0 0 0 41 NOG10239(Parallel beta-helix repeats) 27 85 112 33 5 0 3 20 14 11 1 6 10 22 10 13 2 1 21 29 10 16 38 25 15 4 17 16 16 11 4 38 31 19 74 71 10 12 10 17 6 12 0 1 0 0 0 0 0 0 0 12 0 0 0 7 NOG10010() 29 16 17 26 3 7 14 39 5 22 23 5 5 16 14 12 17 31 19 9 12 12 24 7 18 55 13 17 11 10 11 46 34 37 25 67 6 112 25 16 7 10 0 0 0 0 0 0 0 0 0 3 1 0 0 8 COG4412(Uncharacterized protein conserved in bacteria) 197 20 99 24 0 1 4 2 0 2 8 8 1 10 6 5 3 6 5 14 14 39 49 28 10 34 18 14 11 5 10 8 31 12 11 29 30 71 2 27 9 8 0 0 0 0 0 0 0 0 0 2 0 0 0 28 COG1166(Arginine decarboxylase (spermidine biosynthesis)) 137 24 11 41 4 13 5 7 0 5 7 3 0 12 5 6 1 14 9 7 32 16 42 30 34 50 20 16 38 32 30 43 12 11 31 11 10 76 44 5 3 1 0 0 0 0 0 0 0 0 0 9 1 2 0 5 NOG09472() 4 7 5 5 1 4 1 36 1 5 24 1 12 4 2 1 0 0 21 3 8 11 15 2 3 0 10 2 4 9 1 3 3 4 6 1 3 662 22 2 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG2847(Uncharacterized protein conserved in bacteria) 158 24 36 18 4 5 4 13 3 3 20 1 6 18 9 5 23 20 19 7 11 7 25 10 11 18 10 6 3 2 7 22 16 14 27 38 18 220 9 15 6 10 0 0 0 0 0 0 0 0 0 6 0 0 0 7 COG1078(HD superfamily phosphohydrolases) 26 18 22 41 16 4 5 6 3 1 1 10 2 13 4 7 3 6 12 6 47 45 60 29 30 58 6 12 23 22 19 40 29 15 20 42 25 76 30 25 16 8 0 0 2 0 0 0 0 2 0 10 0 1 0 15 COG0716(Flavodoxins) 282 26 18 23 3 4 0 8 5 7 6 3 4 6 5 0 2 0 4 13 20 10 41 19 30 4 6 10 24 12 19 26 13 6 19 34 31 47 49 34 7 11 0 0 0 0 0 2 0 0 0 16 0 0 0 4 COG0648(Endonuclease IV) 23 14 31 18 1 0 8 10 8 2 0 10 8 10 7 13 37 38 6 27 10 16 24 31 22 110 30 22 15 7 14 26 23 12 13 55 41 53 21 15 16 11 0 0 0 0 0 0 0 0 0 19 0 0 0 36 NOG16951(Phage integrase) 17 17 8 21 14 47 25 30 16 33 47 10 26 86 12 21 14 6 36 4 14 6 29 36 20 0 8 15 11 1 18 29 11 9 40 17 26 52 12 14 7 11 0 0 0 0 0 0 0 0 0 4 0 0 0 32 COG1820(N-acetylglucosamine-6-phosphate deacetylase) 145 29 26 17 3 8 8 12 0 7 0 2 8 1 4 1 15 35 11 10 5 5 12 9 9 68 11 4 9 2 10 30 19 27 35 63 7 161 44 17 9 4 0 0 0 0 0 0 0 0 0 3 0 0 0 7 COG4989(Predicted oxidoreductase) 75 36 21 29 9 5 9 9 6 8 11 17 7 19 17 6 8 15 18 12 14 16 27 17 14 25 22 22 6 3 13 33 40 32 73 56 26 38 29 23 12 11 0 0 0 2 0 0 0 0 0 7 0 0 0 13 NOG14732() 48 47 38 43 0 0 13 20 6 6 4 14 2 6 7 16 11 26 11 12 14 17 37 23 26 13 23 20 25 0 15 21 35 31 75 79 16 12 27 29 8 5 0 0 0 0 0 0 0 1 0 8 0 0 0 21 COG3718(Uncharacterized enzyme involved in inositol metabolism) 71 34 42 19 3 11 17 6 9 9 3 4 8 23 4 7 7 9 18 14 17 13 33 21 22 28 21 22 12 2 12 29 18 41 76 55 13 54 20 37 13 12 0 0 0 0 0 0 0 0 2 6 0 0 0 13 COG1933(Archaeal DNA polymerase II, large subunit) 1 23 71 15 0 0 0 4 5 0 2 7 15 25 14 17 0 1 10 34 15 33 64 11 30 47 19 18 8 11 8 40 44 24 4 54 61 2 18 25 37 14 0 0 2 0 0 0 0 0 0 16 0 0 0 61 NOG17212() 4 20 76 13 14 5 23 11 31 3 8 13 14 16 2 10 4 15 18 21 16 25 31 14 16 17 14 19 13 7 8 44 31 20 69 88 8 62 9 47 11 8 0 0 0 0 0 0 0 0 0 6 0 0 0 6 COG0435(Predicted glutathione S-transferase) 35 29 20 41 6 17 13 15 4 4 2 4 0 28 10 10 5 0 13 22 16 24 49 20 26 1 21 15 17 15 27 45 18 21 58 22 14 105 34 24 18 9 0 0 0 0 1 0 0 0 0 6 0 0 0 25 COG2939(Carboxypeptidase C (cathepsin A)) 352 28 42 19 6 22 11 7 6 3 3 11 2 4 0 3 11 4 9 7 10 3 9 8 10 7 10 18 8 32 7 19 15 19 44 45 7 21 17 19 5 8 0 0 0 0 0 0 0 0 0 9 0 0 0 8 COG4143(ABC-type thiamine transport system, periplasmic component) 25 34 25 27 1 5 5 13 6 4 3 1 14 20 6 2 12 12 12 30 10 8 22 19 13 40 15 8 11 2 11 24 23 27 62 75 14 173 6 39 6 11 0 0 0 0 0 0 0 0 0 9 0 0 0 21 NOG06445(Dependent protein) 33 71 122 50 12 3 25 14 7 4 8 13 9 18 9 4 1 2 3 3 10 36 39 12 24 2 5 14 18 6 9 26 17 22 65 39 10 73 13 15 8 9 0 0 0 0 0 0 0 0 0 7 1 0 0 12 COG3447(Predicted integral membrane sensor domain) 521 45 14 10 3 1 1 6 3 0 16 2 0 8 6 3 17 11 4 0 3 0 4 5 1 7 8 1 5 6 8 2 3 2 4 8 66 93 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2942(N-acyl-D-glucosamine 2-epimerase) 311 14 20 18 10 8 6 14 2 4 13 6 0 18 10 9 12 6 14 10 11 2 13 6 11 20 16 4 5 9 3 9 4 13 22 26 9 177 10 17 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG4619(ABC-type uncharacterized transport system, ATPase component) 97 36 38 39 3 6 25 21 4 4 6 4 4 8 12 5 12 15 10 17 14 20 28 21 28 5 20 14 12 4 6 22 31 15 41 42 12 81 24 25 5 20 0 0 0 0 0 0 0 0 0 7 0 0 0 32 COG1705(Muramidase (flagellum-specific)) 147 12 66 12 9 7 7 16 6 3 5 6 5 16 14 6 7 9 14 1 7 10 7 2 8 9 6 4 8 4 3 23 15 22 52 63 5 200 19 23 19 2 0 0 0 0 0 0 0 0 0 5 0 0 0 9 COG1324(Uncharacterized protein involved in tolerance to divalent cations) 110 31 47 42 0 11 10 0 2 1 1 2 0 7 6 2 7 10 6 14 32 26 33 27 25 27 19 13 22 14 43 35 20 14 33 38 17 66 22 6 8 11 0 0 0 0 0 0 0 0 0 8 0 0 0 24 COG1764(Predicted redox protein, regulator of disulfide bond formation) 330 28 18 24 2 2 6 3 0 4 9 3 1 20 6 4 2 4 10 3 6 8 16 4 7 10 6 3 2 1 1 14 19 12 41 27 6 184 11 19 2 0 0 1 0 0 0 0 0 0 0 10 0 0 0 2 COG5108(Mitochondrial DNA-directed RNA polymerase) 8 9 38 14 6 4 7 87 8 15 36 5 14 12 5 15 4 2 19 14 22 64 105 39 33 8 19 20 18 59 6 18 15 14 11 24 2 17 7 11 10 16 0 0 0 0 0 0 0 0 0 6 1 0 0 23 COG3201(Nicotinamide mononucleotide transporter) 105 46 46 31 15 5 15 15 13 8 10 6 2 14 12 6 36 25 10 12 14 23 22 8 4 80 13 15 9 4 7 18 18 11 60 55 6 18 25 21 8 6 0 0 0 0 0 0 0 0 0 5 0 0 0 7 NOG10802(Protein involved in establishment of localization) 274 17 12 5 6 13 1 6 7 10 7 0 0 20 5 7 22 8 8 0 6 1 13 10 5 10 4 5 3 3 6 9 5 0 13 15 17 312 9 4 3 1 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG1260(Myo-inositol-1-phosphate synthase) 15 13 54 19 1 2 4 6 4 0 0 10 5 14 11 15 30 45 4 12 23 28 29 14 16 144 15 16 8 7 20 17 25 17 28 65 16 72 23 10 15 0 0 0 0 0 0 0 0 0 0 5 0 0 0 11 NOG20088() 36 24 34 51 0 3 17 26 8 7 7 19 6 8 12 4 19 10 3 17 28 22 42 16 14 14 17 22 21 0 20 19 17 37 77 114 14 2 10 26 6 13 0 1 0 0 0 0 0 0 0 12 1 0 0 10 COG3614(Predicted periplasmic ligand-binding sensor domain) 679 20 11 0 0 0 0 3 0 2 0 1 2 2 0 1 6 0 2 2 0 2 2 2 2 8 1 2 6 0 2 1 1 0 3 6 31 83 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09072(Alternative oxidase) 19 46 12 40 2 4 14 14 7 4 7 3 5 9 10 8 6 13 2 8 16 12 29 20 4 1 7 17 18 6 19 45 32 34 103 52 13 67 34 27 6 19 0 1 0 1 0 0 1 0 0 44 0 0 0 24 COG4032(Predicted thiamine-pyrophosphate-binding protein) 112 36 56 57 2 6 5 17 8 10 2 2 8 21 27 8 5 4 18 19 27 6 33 14 27 6 14 16 13 3 5 30 30 14 53 43 24 3 28 33 9 5 0 0 0 0 0 1 0 0 0 4 0 0 0 18 NOG08729() 63 39 30 39 3 6 12 7 6 3 0 10 4 18 0 10 0 5 10 23 9 25 35 18 21 5 14 10 16 3 12 34 37 18 67 79 20 34 30 32 11 20 0 0 0 0 0 0 2 0 0 13 1 0 0 28 COG4695(Phage-related protein) 36 2 6 3 1 4 5 18 4 9 19 4 2 26 10 3 5 10 41 4 1 3 6 6 4 30 10 9 3 10 6 14 11 0 6 4 7 508 4 6 2 4 0 0 0 1 0 0 0 0 0 3 0 0 0 10 COG5525(Bacteriophage tail assembly protein) 21 10 4 9 2 0 2 46 3 7 12 3 16 12 0 1 13 6 27 1 6 8 7 4 3 0 13 4 9 6 2 6 9 2 0 5 10 572 11 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG26669() 9 16 29 19 34 3 35 20 26 8 9 20 11 9 7 2 7 6 4 15 8 14 31 18 7 18 11 12 14 3 15 38 28 29 131 49 8 4 7 74 14 16 0 0 0 0 0 0 0 3 0 9 0 1 0 28 NOG04782() 18 47 119 28 3 4 8 8 8 1 2 8 3 16 6 3 2 4 3 18 16 41 39 11 11 12 6 20 10 2 5 28 26 28 93 75 22 47 10 29 8 11 0 0 2 2 0 0 0 0 0 7 0 0 0 8 COG3396(Uncharacterized conserved protein) 126 20 26 18 6 5 6 4 12 11 12 5 8 36 14 3 16 18 15 24 18 21 38 7 12 25 24 19 8 5 7 29 47 7 24 50 4 81 6 24 12 5 0 0 0 0 0 0 0 0 0 3 0 0 0 17 COG1271(Cytochrome bd-type quinol oxidase, subunit 1) 397 14 3 4 3 0 1 0 0 0 6 0 0 5 6 5 27 18 4 0 5 0 0 3 0 44 5 1 2 0 3 2 5 0 2 3 28 277 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3202(ATP/ADP translocase) 29 94 164 48 4 5 17 16 6 15 1 12 7 25 2 8 5 2 11 20 10 16 21 12 19 19 12 19 5 8 7 27 19 4 58 56 23 10 8 11 5 8 0 0 0 0 0 0 0 0 0 6 0 0 0 3 COG1352(Methylase of chemotaxis methyl-accepting proteins) 277 28 16 18 2 6 0 2 1 1 5 0 0 8 3 2 2 10 6 4 5 2 11 2 5 18 10 5 3 5 2 9 4 6 9 20 88 263 2 7 0 6 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG32651() 369 4 7 5 3 3 2 1 2 1 2 1 4 23 4 2 10 13 11 1 4 5 2 4 2 65 4 2 5 1 0 8 6 1 4 17 5 237 3 3 4 2 0 0 0 0 0 0 0 0 0 1 0 0 0 22 COG1272(Predicted membrane protein, hemolysin III homolog) 99 12 16 7 11 5 13 20 16 5 5 10 9 10 6 2 29 43 11 7 8 7 16 6 6 83 5 12 4 7 3 15 22 18 48 50 2 147 14 26 10 2 0 0 0 0 0 0 0 0 0 1 0 0 0 27 NOG06552(Photosynthetic reaction center M subunit) 17 10 12 21 7 6 7 15 3 3 2 2 8 7 5 1 4 2 4 19 25 19 73 36 30 29 23 32 32 48 24 17 14 16 29 36 3 106 35 22 10 19 0 0 0 0 2 2 0 0 0 18 0 0 0 19 NOG25252() 8 20 90 28 8 4 18 17 9 3 4 14 0 10 10 10 6 3 12 16 17 21 34 15 13 16 16 32 20 5 2 35 35 23 97 59 11 21 24 28 16 16 0 0 0 0 0 0 0 0 0 7 0 0 0 21 NOG17432() 25 44 27 44 0 3 14 5 4 9 4 5 2 12 16 11 11 24 17 22 27 19 32 21 17 10 26 23 13 0 18 37 36 15 84 70 7 19 12 43 13 6 0 0 0 0 0 0 0 0 0 9 0 0 0 15 NOG15993(Nickel-Containing superoxide dismutase) 30 17 24 22 3 4 11 4 5 3 0 2 2 9 10 6 35 8 6 14 25 19 40 27 24 41 17 22 25 17 21 55 35 34 49 59 3 28 26 37 20 9 0 0 1 0 1 0 0 0 0 8 0 0 0 12 COG1579(Zn-ribbon protein, possibly nucleic acid-binding) 4 16 34 12 6 4 12 8 5 2 8 5 7 14 14 5 32 28 13 12 7 15 28 9 14 75 14 25 6 0 4 23 10 16 40 63 4 192 9 40 10 9 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG2761(Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis) 130 14 35 23 3 9 9 47 25 7 17 25 6 26 19 19 37 32 13 21 10 4 11 4 8 24 15 11 7 5 4 20 18 16 29 39 12 54 9 23 8 3 0 0 0 0 0 0 0 0 0 4 0 0 0 11 COG2103(Predicted sugar phosphate isomerase) 23 29 56 24 11 4 18 8 13 13 3 8 6 13 10 6 8 11 11 11 13 26 29 16 6 24 13 13 11 7 4 42 25 15 45 35 8 129 40 28 14 9 0 0 0 0 0 0 0 0 0 8 0 0 0 19 NOG31953() 1 9 23 17 1 13 22 77 10 41 90 2 20 13 17 10 7 12 40 6 6 10 19 15 19 9 25 9 17 21 14 48 44 6 5 22 8 92 7 13 7 6 0 0 0 0 0 0 0 0 0 1 0 0 0 11 COG1259(Uncharacterized conserved protein) 10 23 35 9 9 2 24 5 11 2 2 3 6 3 4 12 21 47 8 13 11 14 25 18 14 99 17 21 15 3 12 24 20 18 55 56 15 88 21 22 9 12 2 0 0 0 1 0 0 0 0 5 0 0 0 18 COG1830(DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes) 14 25 52 21 3 5 9 6 5 2 0 7 4 14 5 1 12 13 6 11 13 9 16 12 10 43 11 13 16 3 15 29 31 19 32 45 27 181 22 22 16 16 0 0 0 0 0 0 0 0 0 10 0 0 2 34 COG1328(Oxygen-sensitive ribonucleoside-triphosphate reductase) 192 34 90 36 0 0 16 6 0 4 0 1 0 16 10 5 12 12 10 15 3 8 19 10 9 38 7 4 7 5 2 22 20 14 19 33 38 92 15 13 7 8 0 0 0 0 0 0 0 0 0 4 0 0 0 6 COG3313(Predicted Fe-S protein) 90 38 51 30 2 0 13 11 8 9 6 5 7 16 9 11 12 8 12 13 5 11 17 17 23 11 33 6 12 5 12 24 30 19 58 38 9 107 16 16 5 13 0 0 0 0 0 1 0 2 0 7 0 0 0 13 NOG19304() 24 15 39 33 3 10 25 25 4 9 11 4 1 8 10 11 7 8 8 12 23 26 25 21 25 28 18 16 16 44 17 28 26 22 42 49 6 79 32 5 12 10 0 0 0 1 0 0 0 0 0 8 0 0 0 14 COG1270(Cobalamin biosynthesis protein CobD/CbiB) 191 23 21 35 3 7 9 3 5 1 9 11 6 8 10 3 6 9 3 4 25 13 30 24 24 16 3 14 17 25 19 17 7 18 26 24 9 122 23 11 4 6 0 0 0 0 0 0 0 0 0 10 0 1 0 5 NOG11356() 155 11 54 10 5 5 5 14 25 8 22 0 10 14 4 6 17 25 25 18 10 19 7 5 5 44 31 34 5 13 8 28 21 9 10 16 52 75 10 5 8 4 0 0 0 2 0 0 0 0 0 3 0 0 0 2 COG2901(Factor for inversion stimulation Fis, transcriptional activator) 75 58 50 40 2 9 10 12 2 8 16 4 3 31 19 7 12 6 8 20 13 11 15 5 13 13 11 10 11 1 10 21 24 17 57 41 17 110 13 20 10 18 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG08769() 11 6 12 9 0 0 9 4 3 0 0 7 9 4 12 19 43 41 8 27 7 9 25 7 11 95 29 14 17 0 7 15 17 32 18 43 7 204 14 8 11 5 0 0 0 0 0 0 0 1 0 5 0 0 0 33 NOG23055() 66 58 61 55 2 5 15 20 7 15 3 5 4 21 9 6 0 2 11 12 20 11 31 19 26 0 15 17 21 5 15 29 32 22 69 60 7 2 14 27 4 14 0 0 0 0 0 0 0 0 1 10 0 0 0 10 COG3367(Uncharacterized conserved protein) 27 32 68 30 3 3 12 8 12 6 4 9 4 30 10 11 6 17 13 9 10 7 18 10 15 5 23 18 12 1 4 21 32 20 51 74 2 144 30 26 3 6 0 0 0 0 0 0 0 0 0 9 0 0 0 3 COG0380(Trehalose-6-phosphate synthase) 236 7 9 11 15 11 21 8 2 5 1 0 2 8 0 4 2 20 7 6 15 9 14 12 5 1 8 7 3 15 4 8 2 2 8 4 16 309 21 6 3 0 0 0 0 0 0 0 0 0 0 6 0 0 0 4 COG1952(Preprotein translocase subunit SecB) 100 22 33 31 2 7 7 21 9 16 13 5 4 25 11 13 4 13 13 9 14 10 19 13 13 13 12 7 2 3 7 19 32 16 33 36 24 162 12 26 5 6 0 0 0 0 0 0 0 0 0 10 0 0 0 4 COG4178(ABC-type uncharacterized transport system, permease and ATPase components) 227 12 19 50 8 11 8 0 0 5 0 0 0 4 4 0 2 16 5 7 33 16 40 43 37 8 13 12 14 35 42 28 4 6 6 5 6 52 53 13 3 0 0 0 0 0 0 0 0 0 0 7 0 0 0 2 COG4337(Uncharacterized protein conserved in bacteria) 23 38 58 28 7 3 16 27 15 8 0 11 12 10 2 6 1 0 2 23 17 31 42 15 30 1 18 24 15 7 6 45 35 21 74 51 2 12 29 31 18 14 0 0 0 0 0 0 1 0 0 9 0 0 0 16 NOG04984(Sialic acid-specific 9-O-acetylesterase) 20 17 20 16 27 11 21 19 6 17 13 7 5 23 9 9 5 20 19 10 11 23 27 10 16 12 11 26 23 29 14 30 28 22 69 38 6 74 23 31 8 14 0 0 0 0 0 1 0 0 0 4 0 0 0 5 COG1230(Co/Zn/Cd efflux system component) 373 27 17 8 6 1 5 4 7 1 4 6 0 17 6 5 32 17 21 2 11 3 5 2 2 93 10 1 6 10 12 6 2 2 5 12 13 77 3 2 0 4 0 0 0 0 0 0 0 0 0 5 3 0 0 0 NOG22780() 824 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 8 0 0 0 0 5 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22508(Tonb-Dependent protein) 279 109 146 52 19 9 20 5 1 6 2 0 0 3 0 2 0 0 5 14 12 18 37 6 11 4 0 4 3 0 4 8 2 2 3 5 0 49 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0829(Urease accessory protein UreH) 109 41 38 53 5 16 8 10 1 4 9 5 4 13 10 5 8 3 7 16 39 9 41 30 32 9 13 10 21 12 28 7 15 7 30 15 4 83 30 12 4 4 0 0 0 0 2 0 0 0 0 3 0 1 0 17 COG1231(Monoamine oxidase) 47 37 80 36 5 7 5 8 6 3 1 4 0 25 8 13 8 3 19 22 2 15 12 7 4 38 9 6 8 14 2 31 12 14 48 123 16 74 17 32 5 9 0 0 0 0 0 0 1 0 0 5 0 0 0 2 COG1868(Flagellar motor switch protein) 141 26 26 20 6 8 5 7 3 9 11 3 13 33 8 9 10 7 18 6 9 4 35 20 20 12 31 12 12 1 12 31 22 21 34 22 15 100 13 19 5 6 0 0 0 0 0 0 0 0 0 8 0 0 0 9 COG3951(Rod binding protein) 296 13 8 5 18 2 12 16 5 2 13 9 4 19 4 7 13 7 11 6 5 9 9 5 10 8 4 3 6 7 4 26 21 18 26 37 8 97 14 24 13 5 0 0 0 0 0 0 0 0 0 4 1 0 0 8 COG3159(Uncharacterized protein conserved in bacteria) 108 38 30 28 4 2 18 7 4 13 7 11 0 17 7 8 8 8 18 13 10 11 26 12 13 4 9 9 9 6 9 21 22 14 56 37 15 149 23 16 8 6 0 0 0 0 0 0 0 0 0 6 0 0 0 2 COG1897(Homoserine trans-succinylase) 92 40 24 31 6 14 6 5 1 11 0 5 3 27 4 8 4 1 13 11 20 13 33 20 31 0 23 15 20 23 19 24 18 12 51 38 2 83 16 18 4 15 0 0 0 0 0 0 0 0 0 14 0 0 0 23 COG1274(Phosphoenolpyruvate carboxykinase (GTP)) 111 14 48 19 2 2 2 2 3 0 2 2 4 21 4 5 37 38 15 7 3 2 4 4 2 116 4 2 6 0 0 1 1 0 6 30 20 287 2 0 0 2 0 0 0 0 0 0 5 0 0 2 0 0 0 4 COG1564(Thiamine pyrophosphokinase) 11 10 49 23 1 4 21 15 2 3 0 9 1 21 5 13 10 16 11 12 15 25 49 21 20 32 26 23 12 4 14 28 30 20 42 53 4 72 28 19 19 8 0 0 0 0 0 0 0 0 0 5 0 0 0 35 COG3816(Uncharacterized protein conserved in bacteria) 39 49 54 41 6 5 10 15 11 7 12 7 5 22 14 8 2 0 19 15 10 15 29 16 15 3 14 14 10 0 14 32 22 26 75 53 4 79 18 14 7 5 0 0 2 0 0 1 0 0 2 8 0 0 0 11 COG2607(Predicted ATPase (AAA+ superfamily)) 141 17 18 25 2 8 8 16 1 12 0 3 2 14 10 6 20 10 13 7 10 4 19 7 8 2 13 9 13 5 6 20 20 10 43 34 10 210 9 27 8 6 0 0 0 0 0 0 0 0 0 6 0 0 0 5 COG0311(Predicted glutamine amidotransferase involved in pyridoxine biosynthesis) 4 18 58 8 0 0 5 4 5 0 0 3 1 31 10 10 27 26 7 22 22 16 30 13 26 88 27 23 13 6 7 21 26 12 13 60 5 120 8 11 21 13 0 0 0 0 0 0 0 0 0 8 1 0 0 7 COG3751(Predicted proline hydroxylase) 82 21 22 26 8 8 3 18 12 5 11 7 3 17 7 7 17 21 13 3 5 13 29 15 13 75 15 10 15 15 9 13 18 13 29 58 10 121 16 7 7 2 0 0 0 0 0 0 0 1 0 3 0 0 0 12 COG0033(Phosphoglucomutase) 92 23 13 32 2 11 6 4 0 1 0 2 0 2 8 4 11 11 7 6 33 2 42 29 28 3 5 9 26 17 23 25 3 10 10 1 29 265 31 1 2 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG1572(Uncharacterized conserved protein) 41 9 25 9 11 3 4 8 11 4 8 2 8 19 9 10 2 13 15 26 1 18 29 14 12 19 9 14 14 4 4 34 37 10 4 29 16 210 12 39 21 13 0 0 0 0 2 0 0 0 0 11 0 0 0 21 COG4533(ABC-type uncharacterized transport system, periplasmic component) 123 10 15 21 6 4 1 2 3 9 6 4 13 22 4 15 0 11 6 15 12 16 19 21 21 14 32 9 6 6 13 18 15 10 36 53 10 178 8 17 8 5 0 0 0 0 0 0 0 0 0 4 0 0 0 11 COG3893(Inactivated superfamily I helicase) 17 9 10 21 2 5 11 17 25 4 13 13 10 44 14 3 14 3 11 13 3 1 4 6 12 25 29 23 5 0 8 22 45 17 54 36 12 169 27 35 6 7 0 0 0 0 0 0 0 0 0 8 0 0 0 17 NOG05956(Selenium-Binding protein) 78 22 14 40 2 10 13 26 10 9 4 8 17 40 4 11 1 4 21 15 9 10 20 9 16 0 22 9 25 5 10 25 28 28 79 51 6 25 21 36 10 19 0 0 4 0 0 0 0 0 0 6 0 0 0 6 NOG26084(Tonb dependent protein) 2 14 77 11 18 0 9 6 14 12 10 8 2 24 10 12 26 28 9 9 16 29 17 4 9 11 18 17 11 4 12 52 24 24 45 59 9 70 9 47 10 7 0 0 0 0 0 0 0 0 0 9 0 2 0 9 COG4635(Flavodoxin) 84 31 42 29 0 1 6 18 2 8 0 2 9 7 1 1 0 2 5 6 7 7 12 15 7 0 0 11 13 6 9 55 31 42 148 61 20 2 23 41 12 19 0 2 0 0 0 1 0 0 0 21 0 0 0 6 COG3145(Alkylated DNA repair protein) 143 17 28 16 16 9 6 11 7 7 7 4 4 20 5 9 10 23 13 15 5 9 18 10 11 38 16 9 8 11 7 21 20 10 21 23 21 158 9 9 4 4 0 0 0 0 0 0 0 1 0 2 0 0 0 8 COG4874(Uncharacterized protein conserved in bacteria containing a pentein-type domain) 69 59 88 47 11 6 11 8 11 9 3 4 4 2 2 2 7 10 9 17 16 23 24 4 18 6 10 3 4 6 5 38 28 27 104 50 4 2 7 36 7 8 0 0 0 0 0 0 0 0 0 5 0 0 0 8 COG1443(Isopentenyldiphosphate isomerase) 11 15 42 19 11 5 22 7 14 9 14 10 2 29 15 2 5 9 6 22 14 16 24 11 7 18 8 11 7 14 4 39 24 10 48 39 3 134 6 37 17 21 0 0 0 0 2 0 1 0 0 5 0 0 0 32 COG1021(Peptide arylation enzymes) 122 13 22 19 1 0 19 19 8 3 2 6 3 6 5 15 16 13 3 17 12 22 39 17 28 27 6 11 11 4 14 29 16 9 32 48 2 115 16 20 8 7 0 0 0 0 0 0 0 0 0 2 0 0 0 13 COG2911(Uncharacterized protein conserved in bacteria) 381 13 13 2 0 0 1 0 0 0 0 3 0 6 6 1 6 2 0 2 2 5 3 2 0 17 4 0 7 0 0 1 1 0 0 4 8 328 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3193(Uncharacterized protein, possibly involved in utilization of glycolate and propanediol) 198 19 28 15 3 6 3 6 4 8 12 4 2 26 6 11 13 12 8 8 5 6 12 4 5 8 13 10 7 1 5 5 11 2 19 17 19 241 3 13 7 2 0 0 0 0 0 0 0 0 0 2 0 0 0 10 COG3956(Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain) 26 26 25 34 4 2 7 11 11 2 4 8 2 4 3 5 14 22 8 20 38 20 53 30 16 64 20 33 29 7 25 19 21 12 30 46 15 30 16 23 8 5 0 0 0 0 0 0 0 0 0 7 0 0 0 12 NOG11065() 811 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3278(Cbb3-type cytochrome oxidase, subunit 1) 65 6 11 3 1 1 3 1 3 0 1 6 3 43 6 9 19 19 16 8 14 14 14 13 13 21 27 11 9 2 6 8 10 22 17 38 35 257 12 10 5 4 0 0 0 0 0 0 0 0 0 3 0 0 0 27 COG1977(Molybdopterin converting factor, small subunit) 175 12 44 23 1 6 3 5 2 4 5 1 2 16 5 4 23 17 8 12 12 8 8 11 6 52 5 3 7 3 8 17 5 13 34 32 15 157 7 20 5 4 0 0 0 0 0 0 0 0 0 6 0 0 0 7 COG2967(Uncharacterized protein affecting Mg2+/Co2+ transport) 80 31 58 33 5 5 4 8 6 5 10 9 11 18 5 9 14 19 10 19 7 7 24 13 7 10 18 15 6 1 8 23 25 16 26 49 14 114 11 22 11 11 0 0 0 0 0 0 0 0 0 5 0 0 0 10 COG3544(Uncharacterized protein conserved in bacteria) 33 72 87 43 2 2 10 24 2 20 1 0 9 19 7 4 11 42 9 7 16 24 23 10 10 73 6 5 19 12 5 19 24 5 43 33 4 24 9 10 10 6 0 0 0 0 2 0 0 0 0 11 0 0 0 4 COG1075(Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold) 107 21 78 26 4 7 7 3 0 1 4 5 0 16 4 3 4 4 11 5 25 12 25 21 25 6 12 8 23 25 24 31 10 10 22 5 12 130 29 16 4 12 0 0 1 0 0 0 0 0 0 6 0 1 0 6 COG3564(Uncharacterized protein conserved in bacteria) 38 24 10 34 0 2 18 21 8 12 3 6 7 7 5 9 11 3 3 13 7 10 21 19 14 7 11 19 24 1 26 44 29 22 51 37 11 131 15 19 9 13 0 0 0 0 1 0 0 1 0 19 0 0 0 15 NOG19096() 5 25 144 21 11 3 8 10 13 5 6 10 11 4 8 4 2 3 11 18 13 34 36 15 8 8 5 37 13 0 10 25 24 7 56 59 4 35 18 43 8 10 2 0 0 0 0 0 0 0 0 7 0 0 0 10 COG4559(ABC-type hemin transport system, ATPase component) 161 1 3 6 1 1 1 4 0 5 8 0 0 11 3 3 16 19 7 0 4 2 1 3 7 58 5 11 8 3 10 34 24 8 59 32 15 213 13 16 8 11 0 1 0 0 0 0 0 0 0 11 0 0 0 1 COG3777(Uncharacterized conserved protein) 216 11 20 25 5 7 4 11 9 7 7 1 2 25 8 5 10 14 8 7 7 6 21 8 13 7 12 11 13 1 20 24 12 14 56 17 5 83 11 24 7 12 0 0 0 0 1 0 0 0 0 7 0 0 0 14 COG1684(Flagellar biosynthesis pathway, component FliR) 138 22 23 17 6 13 7 6 5 6 19 3 7 19 11 7 8 4 7 10 13 8 25 15 10 11 18 16 9 2 14 25 19 9 47 16 14 120 19 20 5 11 0 0 0 0 0 0 0 0 0 11 0 0 0 13 COG3864(Uncharacterized protein conserved in bacteria) 6 16 16 16 0 7 5 41 3 20 55 2 21 19 5 9 12 8 19 8 11 7 11 9 16 74 18 7 11 21 5 17 19 10 13 33 8 193 4 12 1 0 0 0 0 0 0 0 0 0 0 12 0 0 0 8 NOG08451(Terminal oxidase) 8 10 8 23 1 0 1 0 0 0 0 0 0 2 0 3 0 0 0 44 45 38 79 39 40 16 20 32 74 73 59 13 9 17 15 2 0 2 32 6 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 COG2213(Phosphotransferase system, mannitol-specific IIBC component) 29 10 7 16 1 0 19 7 6 3 0 5 1 23 6 15 4 11 9 19 14 15 31 8 8 6 28 26 11 0 8 20 26 23 23 67 9 201 13 7 14 11 0 0 1 0 0 0 0 0 0 11 0 0 0 35 COG0830(Urease accessory protein UreF) 102 46 27 63 3 16 12 13 2 3 2 1 7 11 11 3 6 4 9 13 25 16 42 36 30 14 25 8 25 16 24 11 9 18 41 13 10 39 22 3 3 6 0 0 0 0 0 0 0 0 0 4 0 1 0 11 NOG06233() 19 17 45 25 6 7 5 17 10 20 0 6 12 36 10 10 2 0 9 28 12 24 37 14 27 4 12 14 20 13 8 40 35 32 30 40 8 11 26 40 13 22 0 0 0 1 0 0 0 0 0 8 0 0 2 28 COG2082(Precorrin isomerase) 90 23 28 42 4 9 0 1 4 8 0 0 8 15 16 6 4 0 9 4 44 21 40 25 33 4 13 18 22 25 28 37 17 11 18 13 7 73 29 10 4 14 0 0 0 0 0 0 2 0 0 11 1 2 0 10 COG3185(4-hydroxyphenylpyruvate dioxygenase and related hemolysins) 271 10 45 6 6 7 3 11 9 3 12 6 12 26 14 6 9 10 19 13 8 13 14 7 8 23 26 12 8 3 4 18 15 2 15 13 32 35 5 17 8 5 0 0 0 0 0 0 0 0 0 6 0 0 0 8 COG4235(Cytochrome c biogenesis factor) 113 13 24 14 4 10 3 20 5 7 13 4 6 31 9 9 19 7 23 8 4 5 7 12 5 5 3 14 4 2 2 21 13 7 30 35 18 215 14 18 1 4 0 0 0 0 0 0 0 0 0 7 0 0 0 13 COG2935(Putative arginyl-tRNA:protein arginylyltransferase) 87 21 30 27 6 7 8 5 10 17 11 4 1 30 12 3 7 6 20 19 5 5 14 7 13 14 12 3 7 8 10 19 16 19 53 35 32 124 10 23 6 11 0 0 0 0 0 0 1 0 0 6 0 1 0 15 COG3317(Uncharacterized lipoprotein) 167 47 51 39 4 2 7 11 3 4 11 7 1 8 11 21 21 4 14 13 8 15 27 12 17 2 14 6 13 2 12 25 15 3 42 52 16 20 7 11 10 4 0 0 0 0 0 0 0 0 0 8 0 0 0 12 COG1917(Uncharacterized conserved protein, contains double-stranded beta-helix domain) 142 39 41 30 9 6 13 10 3 7 5 4 1 13 8 4 6 8 3 14 15 13 32 7 23 3 10 10 18 3 6 21 12 15 61 32 8 74 21 21 6 8 0 0 0 0 0 0 0 1 0 6 1 0 0 6 COG3507(Beta-xylosidase) 174 14 33 6 22 19 14 15 17 15 0 13 11 12 6 7 4 11 16 7 7 14 14 10 1 16 4 6 4 3 11 15 20 28 33 30 22 85 12 24 11 4 0 0 2 0 0 0 0 0 0 2 0 0 0 3 COG1010(Precorrin-3B methylase) 138 25 35 56 4 13 5 8 1 2 5 1 4 29 7 5 0 1 6 4 18 24 27 30 38 9 4 14 20 12 21 34 24 9 17 14 5 47 33 18 5 5 0 2 1 0 2 0 0 0 0 11 0 0 0 4 COG4987(ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components) 111 13 13 21 1 2 3 9 5 3 5 18 4 8 19 7 29 23 11 9 14 8 11 5 12 38 14 10 4 4 6 27 19 14 14 34 24 162 19 15 3 11 2 0 0 0 2 0 0 0 0 0 0 0 0 9 COG2820(Uridine phosphorylase) 58 8 25 16 2 2 7 6 6 4 3 15 5 21 16 11 16 27 10 9 22 23 40 14 11 26 13 11 17 2 13 18 17 17 30 77 6 74 18 25 10 6 0 0 0 0 0 0 0 0 0 8 0 1 0 29 COG2368(Aromatic ring hydroxylase) 109 29 52 43 3 3 14 12 6 5 3 8 5 22 17 16 10 0 15 25 17 22 34 19 20 27 24 14 12 0 2 5 12 9 22 84 14 14 12 5 7 4 0 0 0 0 0 0 0 0 0 2 0 0 0 17 NOG06099() 6 20 85 27 11 1 14 14 14 6 9 9 9 22 6 1 10 10 11 18 14 33 32 15 10 15 15 16 6 3 6 55 18 8 51 33 2 82 8 30 9 8 0 0 0 0 0 0 0 0 0 11 0 0 0 12 COG2998(ABC-type tungstate transport system, permease component) 57 27 35 35 1 10 12 19 5 3 4 6 3 27 8 4 12 3 11 12 7 8 32 8 18 8 14 19 11 3 5 31 25 24 35 51 2 86 31 27 10 20 0 0 0 0 0 0 0 0 0 4 0 0 0 21 COG0510(Predicted choline kinase involved in LPS biosynthesis) 28 42 49 34 4 3 17 8 11 8 4 6 10 11 16 18 9 8 10 19 9 24 20 14 16 46 24 15 11 1 6 24 21 22 65 60 8 11 19 24 9 13 0 0 0 0 0 0 0 0 0 1 0 0 0 16 COG1725(Predicted transcriptional regulators) 322 7 10 19 7 3 4 0 5 2 0 2 0 13 4 4 4 0 3 6 25 9 28 21 30 10 8 10 13 10 26 17 6 5 12 10 3 60 29 14 1 6 0 0 2 0 0 0 0 0 0 11 0 0 2 11 COG2519(tRNA(1-methyladenosine) methyltransferase and related methyltransferases) 11 7 30 13 1 2 2 2 0 2 0 5 2 7 10 8 35 53 4 9 14 18 28 9 14 103 15 11 9 3 7 11 14 13 6 43 12 178 8 17 12 12 0 0 0 0 0 0 0 0 0 8 0 0 0 25 COG4750(CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes) 113 23 36 24 1 5 11 7 5 11 0 2 2 8 6 1 6 13 3 20 21 10 14 15 19 63 17 9 9 7 9 21 23 21 51 49 9 27 33 33 6 6 0 0 0 0 0 0 0 0 0 8 0 0 0 16 NOG26156() 2 7 36 12 21 1 22 18 9 8 20 9 11 10 4 8 5 4 4 13 20 23 52 16 20 10 17 18 12 4 5 33 31 24 106 44 6 21 9 57 14 10 0 0 0 0 0 0 0 0 0 7 0 0 0 9 COG1221(Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain) 619 8 6 4 3 0 1 4 3 3 0 0 3 11 6 1 5 1 2 0 0 0 5 1 1 2 5 5 2 4 4 6 4 2 4 2 0 58 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4662(ABC-type tungstate transport system, periplasmic component) 64 28 24 25 1 7 13 11 4 4 3 2 6 17 12 5 17 5 11 9 5 11 32 9 29 4 20 15 13 4 9 32 27 10 44 46 5 105 21 33 12 13 0 0 0 0 0 0 0 0 0 6 0 0 0 19 COG1407(Predicted ICC-like phosphoesterases) 37 25 17 24 14 12 4 3 3 2 3 0 8 13 8 2 0 2 9 8 20 15 35 25 10 9 11 11 8 11 16 35 25 20 33 15 20 201 25 22 5 7 0 0 0 0 0 0 0 0 0 15 0 0 0 4 COG1545(Predicted nucleic-acid-binding protein containing a Zn-ribbon) 56 48 49 37 2 3 7 8 4 11 2 2 10 26 15 5 13 5 15 12 11 30 31 13 9 33 17 17 10 4 8 14 25 12 24 73 10 54 13 12 9 6 0 0 0 0 0 0 0 0 0 8 0 0 0 19 COG3216(Uncharacterized protein conserved in bacteria) 64 21 15 27 4 5 7 10 7 8 7 4 6 20 4 4 2 8 7 3 21 11 38 13 20 3 17 16 9 10 10 31 32 17 40 38 17 150 20 17 6 4 0 0 0 0 0 0 1 0 0 5 0 0 0 11 NOG06757(Carboxysome protein) 40 10 2 31 7 7 4 0 0 1 0 0 0 0 0 0 0 2 0 5 32 28 43 34 34 0 2 12 25 27 24 17 9 4 4 5 1 317 48 4 1 0 0 0 0 0 0 1 0 0 0 4 0 0 0 5 COG4778(ABC-type phosphonate transport system, ATPase component) 117 32 20 35 4 18 32 15 7 3 5 5 9 13 14 4 5 9 5 11 9 14 29 17 11 24 10 8 2 3 7 7 1 4 14 21 10 216 4 2 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG2313(Uncharacterized enzyme involved in pigment biosynthesis) 23 15 47 17 0 7 7 5 2 7 5 3 1 16 3 4 25 15 15 12 15 13 20 7 4 83 9 16 5 5 8 13 20 22 30 48 18 146 14 17 9 8 0 2 0 0 0 0 0 0 0 13 0 0 0 15 COG2982(Uncharacterized protein involved in outer membrane biogenesis) 287 8 8 7 0 2 4 0 10 4 5 1 8 24 4 9 12 12 16 5 1 0 12 2 4 13 7 0 1 2 0 5 0 4 0 16 38 251 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2827(Predicted endonuclease containing a URI domain) 111 36 20 25 1 5 2 9 3 3 11 14 8 11 8 8 23 17 7 10 9 17 13 13 13 34 14 17 9 1 6 25 28 8 37 58 48 61 8 11 7 6 0 0 0 0 0 0 0 0 0 5 0 0 0 8 COG1929(Glycerate kinase) 134 12 22 15 0 2 15 6 3 0 2 13 1 10 10 6 23 19 15 13 19 14 17 17 16 70 20 16 13 1 8 13 16 23 33 55 29 29 6 19 5 11 0 0 0 0 0 0 0 0 0 3 0 0 0 13 COG3290(Signal transduction histidine kinase regulating citrate/malate metabolism) 465 11 9 9 0 1 2 2 0 7 5 4 0 9 2 4 1 6 0 6 15 15 18 14 5 4 7 10 3 2 2 4 2 0 16 9 58 31 6 8 2 7 0 0 0 0 1 0 0 0 0 0 0 0 0 4 COG4798(Predicted methyltransferase) 50 46 89 41 4 1 18 15 8 13 16 13 4 39 17 13 5 0 12 14 13 15 22 12 10 7 12 19 11 3 10 18 14 11 49 44 2 40 8 8 8 15 0 0 0 0 0 0 0 0 0 13 0 0 0 3 COG1704(Uncharacterized conserved protein) 68 2 10 8 6 4 4 0 0 0 4 1 2 28 0 6 38 43 21 7 8 7 14 9 7 119 11 8 8 3 1 17 8 9 15 15 50 188 6 5 2 8 0 0 0 0 0 0 0 0 0 4 0 0 0 11 COG3769(Predicted hydrolase (HAD superfamily)) 53 56 29 47 8 8 19 8 7 3 12 1 6 10 1 6 3 0 7 16 42 24 49 31 35 0 10 16 29 20 40 14 12 8 36 6 13 52 20 14 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG1487(Predicted nucleic acid-binding protein, contains PIN domain) 243 1 2 3 1 0 0 2 0 1 0 0 0 7 0 4 8 4 2 0 0 1 1 0 0 16 0 0 1 1 0 1 0 0 0 0 13 472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11264() 40 43 26 50 0 3 15 22 12 3 3 15 6 8 14 20 5 0 5 31 11 12 30 19 14 0 17 7 11 0 15 31 33 21 69 62 14 14 16 21 11 8 0 0 0 0 0 0 0 0 0 6 0 0 0 16 COG3886(Predicted HKD family nuclease) 40 6 20 14 0 3 0 14 4 3 10 4 4 2 0 8 4 8 6 20 11 6 33 10 32 37 24 15 18 19 13 11 20 36 9 13 8 178 39 11 15 7 0 1 0 0 0 0 0 0 0 6 0 0 0 35 NOG07594() 10 18 20 19 0 0 8 3 1 0 0 3 5 7 2 12 24 22 10 12 17 8 28 15 12 123 20 23 13 0 9 18 20 13 8 51 2 142 19 4 3 14 0 1 0 0 0 0 0 0 0 3 0 0 0 34 COG1142(Fe-S-cluster-containing hydrogenase components 2) 49 27 37 49 3 4 4 5 3 5 1 0 3 27 4 7 7 0 11 10 51 15 47 33 24 19 15 22 17 8 23 18 8 11 22 24 10 100 27 12 4 4 0 0 0 0 0 0 0 0 0 4 1 1 0 0 COG4447(Uncharacterized protein related to plant photosystem II stability/assembly factor) 192 28 38 39 2 6 3 8 5 5 5 1 4 9 4 2 13 12 2 7 31 18 44 25 26 12 14 14 20 13 20 15 3 0 14 23 8 35 27 8 1 0 0 0 0 0 1 0 0 0 0 6 0 0 0 12 COG2738(Predicted Zn-dependent protease) 15 37 50 37 10 9 15 20 5 8 2 5 7 11 7 3 4 5 8 14 17 14 19 13 11 1 5 5 6 3 4 24 26 14 57 30 13 193 11 15 4 3 0 1 0 0 0 0 0 0 0 4 0 0 0 9 COG0132(Dethiobiotin synthetase) 202 23 22 30 2 5 0 8 6 4 8 9 4 10 12 1 20 14 9 1 26 8 30 18 26 27 9 5 13 6 12 12 6 0 11 35 28 78 18 5 3 0 0 0 0 0 0 0 0 0 0 3 0 1 0 3 COG0672(High-affinity Fe2+/Pb2+ permease) 211 26 77 37 1 2 17 3 2 12 2 2 0 17 5 6 28 27 7 7 4 4 18 1 1 145 10 5 1 1 4 10 4 1 16 31 5 16 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG5511(Bacteriophage capsid protein) 18 6 2 9 1 1 0 39 4 5 20 0 15 13 4 0 2 0 15 0 2 4 9 5 4 5 3 3 6 4 4 8 0 4 4 5 2 534 6 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG1240(Mg-chelatase subunit ChlD) 77 14 15 30 2 7 2 6 3 2 1 2 2 17 8 0 12 4 2 11 31 20 31 22 27 25 7 18 22 12 17 32 11 14 35 24 7 113 24 13 6 15 0 0 0 0 0 0 0 0 0 18 0 0 0 10 NOG20057() 6 3 17 9 0 1 5 10 2 5 3 6 6 17 10 6 0 6 8 18 22 30 54 17 25 2 10 32 17 5 12 32 44 15 8 34 13 111 14 46 30 14 0 0 0 0 0 0 0 0 0 4 0 0 0 41 COG2243(Precorrin-2 methylase) 94 27 23 33 6 10 3 6 4 2 1 1 6 22 2 2 3 0 2 6 36 11 36 19 26 9 7 11 25 13 19 34 28 14 54 21 7 57 29 23 5 11 0 2 1 1 0 0 0 0 0 9 0 0 0 9 COG1819(Glycosyl transferases, related to UDP-glucuronosyltransferase) 249 20 55 21 14 2 14 10 4 3 8 1 0 13 4 5 8 2 10 11 13 20 19 14 11 47 2 5 3 2 4 14 16 7 31 12 19 60 2 0 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG1619(Uncharacterized proteins, homologs of microcin C7 resistance protein MccF) 98 15 48 26 9 4 10 2 7 2 3 6 6 10 0 1 19 21 6 1 28 12 27 20 39 20 3 25 16 18 13 26 16 5 9 16 13 92 33 19 7 6 0 0 0 0 0 0 0 0 0 5 0 0 0 5 COG3335(Transposase and inactivated derivatives) 132 15 8 3 3 2 0 14 11 1 15 2 6 16 7 1 9 8 19 0 2 2 4 5 0 18 6 0 1 1 0 6 1 0 0 4 93 350 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07600() 24 64 73 45 2 6 19 2 14 5 3 3 4 21 7 8 4 6 26 16 9 16 28 11 13 36 16 12 15 5 10 26 17 18 57 48 0 14 6 26 6 6 0 0 0 0 0 0 0 1 0 10 0 0 0 8 NOG08718() 2 19 32 28 0 5 11 62 3 9 18 2 19 33 12 19 11 18 84 12 9 3 23 17 11 15 19 6 2 24 11 34 23 4 18 1 7 99 9 2 7 8 0 0 2 0 0 0 0 0 2 6 0 0 0 5 COG1338(Flagellar biosynthesis pathway, component FliP) 128 16 13 20 3 10 8 5 6 9 7 3 2 22 10 8 11 4 9 6 15 23 30 12 19 12 25 12 13 1 10 23 17 4 42 16 20 94 13 19 8 9 0 0 0 0 0 0 0 0 0 12 0 0 0 16 COG3395(Uncharacterized protein conserved in bacteria) 117 11 4 31 2 9 5 6 6 1 5 3 3 14 0 6 5 6 8 2 30 12 41 21 25 5 14 13 26 18 14 25 17 11 10 11 2 158 35 11 4 4 0 0 0 0 0 2 0 0 0 5 0 2 0 5 COG3425(3-hydroxy-3-methylglutaryl CoA synthase) 12 32 58 27 13 5 10 7 7 1 0 6 6 24 12 1 4 0 1 13 23 26 29 11 6 31 11 20 10 7 3 29 31 11 42 66 26 25 10 34 22 23 0 0 0 0 0 0 0 0 0 6 0 4 0 18 COG3103(SH3 domain protein) 61 21 42 12 6 2 6 16 3 11 3 13 8 9 12 6 11 8 13 6 4 15 14 7 10 23 27 14 7 3 6 20 30 18 68 48 37 72 12 30 7 9 0 1 0 0 0 0 0 0 0 7 0 0 0 4 COG3828(Uncharacterized protein conserved in bacteria) 22 27 38 28 4 15 17 5 5 1 7 5 11 10 8 5 4 9 6 4 19 16 34 13 15 16 12 18 11 2 20 16 14 25 51 37 8 131 20 24 10 2 0 0 2 0 0 0 0 2 0 9 0 0 0 3 COG3156(Type II secretory pathway, component PulK) 219 50 73 42 3 6 13 13 4 0 1 3 0 16 7 8 9 3 4 4 2 14 22 9 16 5 5 18 8 4 8 23 19 4 39 12 5 37 8 9 5 7 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG0158(Fructose-1,6-bisphosphatase) 118 24 25 17 11 15 7 15 4 3 9 9 6 6 5 6 12 13 13 18 11 7 11 14 9 23 14 3 9 13 6 17 11 12 17 33 37 147 5 6 4 6 0 2 0 0 0 0 0 0 0 3 0 0 0 5 COG3806(Anti-sigma factor) 61 19 16 8 1 3 10 10 9 5 13 10 15 33 10 11 16 12 15 11 9 7 10 3 16 2 14 10 8 2 6 15 14 4 51 25 25 197 20 13 3 5 0 0 0 0 0 0 0 0 0 7 0 0 0 6 NOG09983(Tola protein) 185 29 39 23 5 1 9 9 0 7 8 4 1 17 8 6 13 6 10 6 8 6 12 13 10 3 9 2 4 4 5 24 20 8 49 43 23 97 11 11 3 2 0 1 0 0 0 0 0 0 0 3 0 0 0 2 NOG15786() 24 33 52 33 6 10 27 18 11 11 5 8 10 16 12 10 3 5 15 22 14 14 28 22 12 1 13 16 17 1 11 25 24 23 59 67 7 1 17 22 9 10 0 0 0 0 0 0 0 0 0 9 0 0 0 5 COG3280(Maltooligosyl trehalose synthase) 189 14 12 1 2 0 2 1 0 3 6 2 2 6 4 2 11 28 4 4 3 7 9 0 2 79 8 10 3 1 2 4 3 2 7 19 4 282 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG5283(Phage-related tail protein) 18 4 7 3 3 1 3 19 4 0 32 3 16 5 6 2 7 9 16 4 9 2 5 5 0 43 5 1 6 2 2 8 7 8 0 4 8 463 4 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG3484(Predicted proteasome-type protease) 76 90 45 77 8 18 52 1 1 0 0 0 5 9 0 8 21 17 4 16 22 35 58 38 32 7 5 9 25 2 13 0 1 4 12 4 0 22 0 2 0 2 0 0 0 0 0 0 0 0 0 6 0 0 0 6 COG3019(Predicted metal-binding protein) 109 68 27 45 7 8 9 3 7 1 6 1 6 12 7 6 6 3 7 18 21 20 30 24 21 1 8 16 15 16 14 19 22 9 43 19 5 50 8 12 6 3 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG2828(Uncharacterized protein conserved in bacteria) 139 26 17 19 6 14 19 16 2 7 4 2 2 42 10 5 24 32 18 15 5 17 18 14 14 15 27 5 17 2 1 10 14 10 23 11 39 25 9 15 4 4 0 0 0 0 0 0 0 0 0 3 0 2 2 25 NOG14665() 8 7 11 8 0 1 0 36 3 15 33 12 9 2 4 4 0 26 10 9 24 22 85 45 46 45 18 14 27 59 15 22 21 9 18 18 0 2 8 8 3 2 0 0 0 0 0 0 0 0 0 5 1 0 0 35 COG3550(Uncharacterized protein related to capsule biosynthesis enzymes) 186 24 3 2 0 0 0 1 0 0 3 2 0 1 2 1 7 10 5 0 2 0 2 1 0 1 1 0 2 1 0 1 0 0 0 0 26 462 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3408(Glycogen debranching enzyme) 171 53 42 71 1 5 22 3 0 0 0 0 0 3 0 3 4 7 5 11 22 10 43 29 13 4 14 15 17 0 20 4 4 8 43 22 7 30 8 2 1 12 0 0 0 0 0 0 0 0 0 5 0 0 0 15 COG1085(Galactose-1-phosphate uridylyltransferase) 32 35 30 32 11 0 11 9 1 1 2 4 7 8 3 4 27 61 4 6 13 4 10 9 14 169 8 7 10 1 7 5 10 5 38 30 15 47 15 17 8 2 0 0 0 0 0 0 0 0 0 4 0 0 0 12 COG3741(N-formylglutamate amidohydrolase) 166 12 22 22 2 8 7 12 9 2 3 6 4 25 8 3 10 13 17 5 4 9 8 11 8 11 11 5 17 1 10 22 25 8 63 31 15 81 15 15 4 3 0 1 1 0 0 0 0 0 0 0 0 0 0 13 NOG38696() 1 1 1 0 0 2 0 11 1 2 11 2 2 7 2 1 1 1 12 5 0 1 0 3 0 19 5 0 2 3 2 12 8 0 2 1 0 614 2 2 1 4 0 0 0 1 0 0 0 0 0 1 0 0 0 1 COG0427(Acetyl-CoA hydrolase) 282 27 11 15 1 0 2 0 0 0 0 1 0 5 6 1 23 7 16 0 2 7 8 2 5 10 11 2 0 0 0 6 7 2 0 3 9 273 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1943(Transposase and inactivated derivatives) 232 5 10 5 1 0 0 0 0 0 2 0 0 13 1 1 11 13 3 0 0 2 4 2 3 11 7 2 1 0 2 2 0 0 4 0 132 267 2 1 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG1696(Predicted membrane protein involved in D-alanine export) 33 18 28 14 7 6 6 6 17 0 18 8 6 26 10 7 13 21 13 20 18 7 24 11 13 21 10 13 9 1 10 29 25 20 39 52 44 65 9 22 9 10 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG0594(RNase P protein component) 68 19 21 34 3 3 6 8 2 6 9 4 11 35 7 9 23 7 12 8 26 11 28 12 12 40 7 11 17 5 12 23 13 6 42 63 21 61 8 15 3 7 0 0 0 0 0 0 1 0 0 3 0 0 0 2 NOG23936() 35 18 15 33 2 2 9 16 2 13 7 19 5 33 11 9 11 6 9 19 28 10 18 15 7 0 13 19 12 0 18 36 19 20 57 67 21 0 24 34 4 11 0 0 0 0 0 1 0 0 0 11 0 0 0 24 COG0393(Uncharacterized conserved protein) 41 37 62 35 12 1 10 14 12 12 5 4 10 27 8 4 7 0 8 18 11 25 28 18 10 1 4 7 10 6 1 21 11 11 63 45 8 49 14 34 13 2 0 0 0 0 0 0 0 0 2 9 0 0 0 11 COG1555(DNA uptake protein and related DNA-binding proteins) 176 4 4 2 7 3 4 1 3 4 8 0 2 13 2 6 24 26 12 4 2 0 3 2 1 73 0 1 1 6 1 6 4 4 4 2 19 289 13 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 COG0798(Arsenite efflux pump ACR3 and related permeases) 362 18 35 37 9 3 1 0 8 2 5 8 0 11 0 8 10 9 10 4 10 14 12 11 6 13 0 4 4 6 0 1 5 0 6 5 7 89 0 3 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1903(Cobalamin biosynthesis protein CbiD) 91 35 41 31 4 7 3 3 2 4 0 3 5 24 4 6 0 8 6 10 34 10 45 24 37 22 6 18 20 13 23 22 9 8 24 10 5 44 37 11 6 9 0 1 0 0 0 0 0 0 0 12 1 0 0 1 COG1782(Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain) 132 23 48 32 1 9 2 7 1 0 6 2 6 15 11 1 4 4 5 9 15 27 29 18 9 37 2 4 12 5 0 10 16 8 20 34 39 50 11 25 15 7 0 0 0 0 0 0 0 0 0 6 0 0 0 22 COG2331(Uncharacterized protein conserved in bacteria) 52 32 34 22 2 0 11 6 4 17 5 5 5 12 2 7 30 25 9 14 9 13 20 12 9 67 13 9 8 3 2 19 11 6 31 26 9 153 2 9 4 3 0 0 0 0 0 0 0 0 0 5 0 0 0 2 COG4067(Uncharacterized protein conserved in archaea) 113 20 20 14 2 0 16 11 1 1 11 2 5 36 12 16 13 5 12 18 15 19 25 12 12 5 23 12 16 4 13 15 19 11 11 31 47 63 14 9 7 8 0 0 0 0 0 0 0 0 0 0 0 0 0 19 COG2904(Uncharacterized protein conserved in bacteria) 119 44 47 22 3 4 7 8 1 20 17 3 2 25 4 7 9 14 17 13 10 7 25 7 7 19 9 5 9 5 9 4 11 10 36 30 20 92 5 10 6 6 0 0 0 0 0 0 0 0 0 6 0 0 0 4 COG1796(DNA polymerase IV (family X)) 117 19 10 9 4 6 4 21 20 1 3 10 11 25 16 9 21 30 8 11 12 22 15 6 7 34 10 9 5 3 9 10 24 12 10 46 26 68 2 12 19 9 0 0 0 0 0 0 0 0 0 7 0 0 0 6 NOG06360() 38 77 75 65 3 2 13 8 0 10 2 10 0 3 0 3 4 0 3 16 22 21 45 20 16 0 10 8 18 3 15 22 9 23 51 55 5 0 21 10 5 9 0 0 0 0 0 0 0 0 0 14 0 0 0 2 COG1113(Gamma-aminobutyrate permease and related permeases) 679 0 2 0 0 0 0 0 0 0 0 0 0 4 2 0 4 3 2 0 0 0 0 1 1 9 1 0 8 0 2 2 0 0 2 4 0 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2241(Precorrin-6B methylase 1) 103 25 36 40 4 6 3 10 4 5 3 2 3 32 5 8 2 1 5 2 23 23 29 19 28 17 4 13 16 25 9 20 9 8 29 19 5 58 33 22 9 5 0 0 0 3 0 0 0 0 0 4 0 0 0 5 COG3876(Uncharacterized protein conserved in bacteria) 14 23 80 30 2 8 8 9 6 9 14 7 8 11 8 6 7 9 24 10 9 15 31 7 18 22 13 8 8 6 9 34 20 17 41 41 15 64 8 37 5 4 0 0 0 0 0 0 0 0 0 5 0 0 0 4 COG3505(Type IV secretory pathway, VirD4 components) 557 2 2 2 0 0 1 0 0 0 0 0 0 10 6 0 0 0 0 0 3 2 0 0 0 1 1 0 3 2 2 0 0 0 0 0 14 124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG20803() 38 47 31 38 5 7 15 19 1 5 10 10 8 10 8 11 25 17 6 17 9 10 34 19 30 7 5 22 17 0 14 28 22 17 61 25 11 26 5 14 5 6 2 0 0 0 0 0 0 0 0 6 0 0 0 9 NOG04762(Photosystem I protein) 42 18 11 51 13 14 1 0 0 4 0 0 0 0 2 2 0 0 5 4 48 24 59 33 37 0 9 20 21 34 41 31 6 10 11 6 0 50 52 4 4 29 0 0 0 0 0 0 0 2 0 32 2 0 0 0 COG1426(Uncharacterized protein conserved in bacteria) 149 13 23 5 0 3 4 5 1 0 5 2 0 14 0 1 20 19 4 6 3 1 4 6 5 54 9 1 3 1 5 8 6 4 14 19 23 279 4 4 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG0467(RecA-superfamily ATPases implicated in signal transduction) 26 14 7 33 5 6 2 0 0 2 0 1 0 2 2 2 2 13 1 14 41 25 49 46 44 5 9 14 14 32 21 39 23 16 11 18 56 56 19 6 4 19 0 1 0 0 0 0 0 1 0 6 0 0 0 22 COG4558(ABC-type hemin transport system, periplasmic component) 97 1 2 2 0 2 0 0 0 0 0 0 0 0 2 0 9 8 6 0 1 0 5 1 0 44 1 10 9 5 4 29 33 15 68 36 7 254 10 26 11 12 0 1 0 0 0 0 0 0 0 13 0 0 0 4 COG3576(Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase) 191 15 11 16 3 1 4 1 1 1 3 2 0 21 10 10 9 3 14 11 15 14 23 15 8 32 9 6 10 1 8 17 6 13 28 43 8 90 9 12 10 8 0 0 0 0 0 0 0 0 0 5 0 1 0 9 NOG07965() 4 13 39 16 24 1 22 7 9 3 5 8 0 12 6 6 7 4 7 16 11 14 12 9 1 14 22 21 16 1 6 32 30 46 105 45 6 6 27 38 16 16 0 0 0 0 0 0 0 0 0 5 0 0 0 19 COG1294(Cytochrome bd-type quinol oxidase, subunit 2) 337 13 3 2 1 0 0 0 0 0 3 0 0 5 4 3 22 20 3 0 0 0 1 1 0 36 7 0 1 0 3 2 0 4 2 4 25 214 1 2 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG0429(Predicted hydrolase of the alpha/beta-hydrolase fold) 156 30 17 30 5 3 2 3 2 4 11 3 8 4 6 6 6 8 6 5 38 13 34 16 33 11 11 12 12 21 26 26 5 2 8 11 18 65 25 2 2 6 0 0 0 1 0 0 0 0 0 4 0 0 0 8 COG3903(Predicted ATPase) 639 2 6 0 1 0 0 0 0 0 0 1 0 4 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 3 1 0 0 0 0 1 8 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1340(Uncharacterized archaeal coiled-coil protein) 17 26 57 38 8 0 1 12 3 12 2 8 5 5 6 17 8 4 27 23 24 19 34 18 14 11 11 17 14 9 9 34 20 10 14 50 10 45 16 20 16 14 0 0 0 0 0 0 0 0 0 5 0 0 0 11 COG0282(Acetate kinase) 183 11 6 2 1 1 2 1 0 0 2 0 0 13 7 0 16 8 12 1 0 0 10 2 0 9 4 2 2 1 0 2 3 0 4 2 33 373 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1457(Purine-cytosine permease and related proteins) 353 8 5 5 0 0 0 4 1 4 3 0 4 4 0 0 33 16 1 4 0 0 2 2 4 64 1 1 4 0 2 1 5 3 18 6 2 152 2 1 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG35086() 23 16 8 24 1 2 2 17 3 1 0 1 2 0 2 0 0 0 0 6 41 23 78 58 71 7 15 34 72 76 37 14 7 8 13 4 0 13 11 4 6 4 0 0 0 0 0 0 0 0 0 0 0 1 0 17 COG3480(Predicted secreted protein containing a PDZ domain) 8 10 15 6 1 0 8 4 0 0 2 3 2 22 0 17 39 41 11 13 8 6 12 12 15 80 24 13 8 0 8 21 19 5 8 49 4 173 14 6 6 3 0 0 0 0 0 0 0 0 0 6 0 0 0 16 COG2121(Uncharacterized protein conserved in bacteria) 17 43 77 34 0 7 9 12 5 4 2 7 2 6 10 4 4 4 9 17 7 11 23 17 11 15 24 14 12 2 0 19 27 27 46 65 4 61 16 4 7 8 0 0 0 0 0 0 0 0 2 9 0 0 0 13 COG5424(Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C) 92 38 51 43 1 3 3 12 2 3 1 3 4 12 8 16 22 19 6 7 20 16 16 19 26 39 11 15 14 2 5 14 19 19 19 51 9 10 7 13 7 7 0 0 0 0 0 0 0 0 0 6 0 0 0 6 NOG16566() 18 24 23 33 1 3 11 32 18 10 14 12 10 8 14 21 25 19 19 18 11 11 13 24 14 16 15 14 13 1 11 25 24 20 53 36 14 10 13 12 7 4 0 0 0 0 0 0 0 0 0 7 0 0 0 15 COG5640(Secreted trypsin-like serine protease) 42 7 17 19 12 22 1 8 3 8 8 2 1 7 0 5 12 21 10 11 6 7 18 6 14 40 2 4 9 14 2 29 29 8 8 66 2 176 16 10 22 2 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG3483(Tryptophan 2,3-dioxygenase (vermilion)) 63 12 37 10 2 2 1 3 8 4 8 5 6 8 8 5 27 45 11 14 13 17 26 15 11 109 10 11 5 5 1 8 19 11 12 20 5 96 6 11 10 5 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG1223(Predicted ATPase (AAA+ superfamily)) 33 23 30 39 6 8 7 2 4 0 4 0 6 9 15 7 14 12 11 21 28 28 26 20 19 33 11 21 12 6 7 14 20 12 27 48 7 41 22 10 11 12 0 0 0 1 0 0 0 0 0 10 0 0 0 18 NOG04570(5-Nucleotidase) 75 56 54 32 4 5 6 12 5 12 8 5 8 12 8 12 5 4 23 14 12 6 26 15 9 11 11 7 11 8 5 18 21 17 61 48 9 10 12 17 1 7 0 0 0 0 0 0 0 0 0 6 0 0 0 6 COG2610(H+/gluconate symporter and related permeases) 214 18 23 11 1 4 11 8 10 0 13 8 5 3 9 6 4 10 12 15 10 4 7 5 7 10 12 16 7 2 2 22 16 10 37 34 4 79 9 16 5 0 0 0 0 0 0 0 0 1 0 2 0 0 0 11 COG1368(Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily) 223 20 35 11 5 2 1 9 7 8 3 0 7 28 11 10 30 15 13 8 17 10 22 5 6 22 20 6 5 0 4 11 16 16 19 25 11 4 6 17 8 2 0 0 0 0 0 0 0 0 0 3 1 0 0 11 COG0638(20S proteasome, alpha and beta subunits) 11 21 71 20 5 15 0 0 3 1 4 6 1 9 15 1 2 22 3 16 15 23 23 12 1 82 6 4 11 29 5 8 18 2 2 55 25 104 3 13 11 2 0 0 0 0 0 0 0 0 0 6 0 0 0 24 NOG06021(Peptidyl dipeptidase) 64 71 78 42 0 1 10 4 8 13 6 6 3 17 11 8 4 2 7 17 9 10 23 5 10 0 11 9 6 8 3 31 17 20 66 47 9 3 11 15 4 11 0 0 0 0 0 0 0 0 0 5 0 0 0 5 COG1714(Predicted membrane protein/domain) 96 32 35 30 9 4 17 9 0 1 12 3 0 19 17 8 17 10 17 10 7 5 21 9 9 9 9 14 12 3 10 14 8 8 35 36 28 92 11 11 1 2 0 0 0 0 0 0 0 0 0 6 0 0 0 2 COG3604(Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains) 191 19 21 11 3 9 1 2 0 0 3 2 2 8 5 2 7 6 7 5 4 8 9 11 6 40 7 7 5 3 4 6 4 2 27 14 41 191 2 3 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG10760() 21 34 26 28 1 1 7 19 1 10 5 10 1 8 5 12 20 18 6 15 19 25 21 25 14 10 18 17 7 3 16 29 34 17 46 53 5 10 15 17 14 10 0 0 1 0 0 0 0 0 0 5 0 0 0 29 COG1188(Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)) 100 11 20 13 11 11 8 17 8 7 9 5 6 25 10 8 6 4 19 6 2 3 8 8 7 4 8 5 4 1 4 21 32 18 53 25 16 121 8 29 13 2 0 0 0 0 0 0 0 0 0 0 0 0 0 11 COG4310(Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain) 27 38 48 49 1 8 10 7 3 0 4 9 3 1 14 8 14 4 5 9 18 3 19 14 12 26 7 17 12 3 8 16 19 21 40 77 13 76 10 12 3 6 0 0 0 0 0 0 0 0 0 4 0 1 0 7 NOG11246() 16 19 22 34 0 4 9 33 15 10 11 23 11 16 10 11 6 1 10 9 12 8 22 6 9 0 12 12 12 3 8 24 34 31 40 35 18 84 18 23 9 3 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG3669(Alpha-L-fucosidase) 16 13 36 26 4 7 11 17 8 8 16 4 7 27 2 4 9 18 15 10 5 3 13 5 20 24 16 14 8 8 15 28 2 24 89 39 12 39 14 33 9 8 0 0 0 1 0 0 0 0 0 12 0 0 0 7 NOG06017(Tryptophan halogenase) 129 8 4 3 0 3 3 21 15 10 15 6 14 12 0 1 7 11 6 7 22 11 40 9 11 72 13 19 24 51 12 15 11 5 9 26 10 6 16 11 4 2 0 0 0 0 2 0 0 0 0 7 0 0 0 21 COG1015(Phosphopentomutase) 67 12 18 12 0 0 12 14 3 1 0 2 2 25 10 11 9 2 12 9 13 17 21 16 10 1 16 17 9 0 7 27 33 20 42 58 12 54 17 24 15 13 0 2 0 1 0 0 1 0 0 9 0 0 0 27 COG4247(3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)) 50 83 78 56 18 4 37 4 2 3 2 5 0 18 2 6 5 1 5 11 12 14 31 15 13 5 2 9 12 1 13 19 19 12 38 32 11 24 9 3 2 4 0 0 0 0 0 0 0 0 0 3 0 0 0 10 NOG10074() 94 39 22 33 2 2 13 24 2 9 0 10 11 15 7 4 7 10 7 19 12 9 24 13 15 9 9 15 17 0 12 18 12 15 41 65 6 18 22 5 4 11 0 0 0 0 1 0 0 1 0 9 0 0 0 7 NOG13035() 23 39 65 48 11 0 9 16 3 0 1 8 6 7 11 4 10 1 7 9 11 20 23 18 13 1 13 10 15 1 14 27 27 10 38 72 13 39 10 16 8 4 2 0 0 0 0 0 0 0 0 5 0 0 0 11 NOG08628() 44 25 16 34 0 5 11 62 19 7 14 17 17 31 18 9 26 39 14 15 19 6 14 10 17 1 8 5 10 11 8 8 2 2 19 45 8 53 4 12 0 6 0 0 0 0 0 0 0 0 0 6 0 0 0 1 NOG16629() 43 30 59 15 5 2 3 5 2 1 0 5 5 14 6 0 2 4 5 5 9 21 17 4 11 6 9 7 16 11 7 11 16 8 18 37 22 204 7 20 10 4 0 0 0 0 0 0 0 0 0 7 0 0 0 5 COG4161(ABC-type arginine transport system, ATPase component) 316 21 20 20 4 1 2 4 2 2 6 10 7 4 2 6 4 10 2 12 7 5 10 9 8 26 16 7 3 1 7 8 6 8 16 25 6 47 3 14 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG12570(Transcription protein) 9 8 18 5 0 0 8 1 4 2 1 4 0 19 12 10 20 31 16 20 17 11 27 14 13 82 18 9 15 0 12 14 17 15 13 39 0 114 18 6 14 1 0 0 0 0 0 0 0 0 0 14 0 0 0 24 COG2063(Flagellar basal body L-ring protein) 124 19 18 10 4 9 12 16 3 0 0 1 10 25 9 6 9 7 17 7 8 7 7 8 5 7 14 5 7 3 5 17 22 10 37 18 15 133 14 16 4 10 0 0 0 0 0 0 0 0 0 8 0 0 0 9 NOG20064() 27 59 69 55 1 0 9 19 10 5 4 3 7 8 6 5 22 7 4 14 6 13 11 6 16 2 6 12 8 0 4 12 25 14 21 126 16 1 10 20 10 7 0 0 0 0 0 0 0 0 0 3 0 0 0 12 NOG04763(Photosystem protein) 42 17 12 52 11 9 2 0 0 2 0 0 0 2 0 2 0 0 1 4 50 20 65 30 42 1 6 23 25 26 45 38 3 4 17 2 0 46 38 5 5 21 0 0 0 0 0 0 0 0 0 26 1 0 0 0 COG0023(Translation initiation factor 1 (eIF-1/SUI1) and related proteins) 35 16 36 16 6 6 6 4 7 5 5 4 7 9 7 7 9 4 12 8 22 10 23 23 30 13 12 14 16 14 12 28 12 13 9 22 24 102 33 19 12 1 0 0 0 0 0 0 0 0 2 8 0 0 0 10 COG4787(Flagellar basal body rod protein) 176 22 5 10 3 3 9 14 4 2 5 6 3 12 5 4 2 4 9 9 6 8 7 17 8 5 12 6 7 3 7 28 13 15 70 29 6 95 8 13 4 5 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1639(Predicted signal transduction protein) 450 28 7 7 0 5 2 1 0 0 9 0 0 2 6 0 6 2 14 3 2 7 2 4 0 6 3 0 6 7 1 8 1 0 2 5 47 43 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 1 COG2818(3-methyladenine DNA glycosylase) 106 25 19 10 5 5 8 7 13 2 17 3 13 28 10 8 11 18 23 6 7 6 11 8 15 26 9 12 4 3 8 7 9 11 24 44 56 58 5 9 5 8 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG4653(Predicted phage phi-C31 gp36 major capsid-like protein) 4 2 1 1 1 3 2 7 3 2 28 1 11 9 8 4 4 1 12 5 0 4 2 1 3 5 5 3 1 11 2 6 13 7 12 3 7 481 5 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG12130() 24 29 13 33 2 6 9 30 14 1 4 18 4 2 20 15 23 9 9 8 13 13 27 19 21 0 9 9 17 5 29 32 36 18 65 23 6 2 8 16 7 6 0 0 0 0 0 0 0 0 0 18 0 0 0 16 NOG18957() 21 6 9 17 0 0 0 7 3 0 0 4 7 10 6 2 3 4 12 1 0 1 1 3 2 15 9 11 0 2 1 0 0 0 4 9 12 501 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG29805() 14 12 41 11 2 4 8 13 16 6 9 17 7 24 9 11 18 15 14 6 6 5 12 12 8 22 20 22 8 1 7 31 22 20 69 60 9 24 1 34 10 5 0 0 0 0 0 0 0 1 0 10 0 0 0 8 COG5571(Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion) 371 19 19 23 0 0 4 15 5 4 2 4 6 4 6 1 2 2 0 11 7 18 20 23 12 0 2 6 7 0 8 0 3 6 19 30 2 2 5 0 2 6 0 0 0 0 0 0 0 0 0 2 1 0 0 5 COG2205(Osmosensitive K+ channel histidine kinase) 370 11 14 13 3 1 5 6 0 1 4 1 0 4 3 2 13 10 2 3 6 8 15 8 11 13 8 5 10 6 3 3 7 3 16 16 8 48 8 6 2 3 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3975(Predicted protease with the C-terminal PDZ domain) 238 5 18 8 8 2 4 2 10 2 5 2 3 11 6 1 16 31 2 6 5 7 3 7 4 35 9 8 4 10 1 27 13 8 6 15 10 64 24 14 9 10 0 0 0 0 0 0 0 0 0 3 0 0 0 7 COG0701(Predicted permeases) 184 18 25 15 2 3 6 4 4 2 13 2 0 16 0 6 2 5 8 2 1 13 15 8 6 4 6 6 3 4 3 10 2 4 10 3 25 219 11 2 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 5 COG0368(Cobalamin-5-phosphate synthase) 141 21 18 40 8 10 9 0 0 4 0 2 7 5 6 4 0 0 3 11 28 19 33 17 19 11 5 13 17 14 30 21 9 9 14 13 7 61 22 12 1 2 0 0 0 0 0 0 0 0 0 8 0 0 0 8 NOG05970(Branched-Chain amino acid ABC protein) 21 21 21 22 0 6 8 1 3 1 2 3 3 23 8 5 10 14 5 10 22 9 15 11 11 41 14 19 17 0 16 13 17 28 66 44 9 76 15 14 2 11 0 0 0 0 0 0 0 3 0 13 0 1 0 7 NOG07792() 27 53 65 26 5 2 9 7 8 7 7 9 2 21 2 8 0 2 10 7 6 8 21 16 7 0 7 11 10 9 3 24 16 13 53 30 16 113 11 15 2 2 0 0 0 0 0 0 0 0 0 4 0 0 0 5 COG1886(Flagellar motor switch/type III secretory pathway protein) 147 31 37 27 2 9 3 3 3 7 4 0 6 23 4 8 9 5 10 3 2 13 28 15 22 6 14 12 8 1 5 23 9 4 30 16 21 59 7 20 3 3 0 0 0 0 0 0 0 0 0 8 0 0 0 9 NOG17121(DNA maturase) 0 6 13 17 3 3 6 46 10 14 9 5 28 6 7 5 0 4 22 9 15 33 74 33 37 3 20 16 21 61 11 14 23 11 12 26 3 23 4 3 5 8 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG3568(Metal-dependent hydrolase) 135 9 29 12 4 3 8 10 2 1 6 2 1 19 6 5 37 29 12 1 2 14 18 7 7 89 15 5 2 2 4 9 8 4 39 16 9 71 2 8 2 4 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG0832(Urea amidohydrolase (urease) beta subunit) 70 38 33 52 7 11 3 4 2 10 7 7 7 13 8 1 8 5 8 12 30 8 33 19 28 1 8 4 15 8 17 3 12 9 23 18 7 77 18 10 1 2 0 0 0 0 1 0 0 0 0 2 0 0 0 17 COG1652(Uncharacterized protein containing LysM domain) 107 8 17 16 2 7 5 10 9 9 13 7 4 26 9 8 8 5 12 1 9 6 10 9 14 1 10 7 14 5 6 20 32 7 38 28 29 92 13 18 4 8 0 0 0 0 0 0 0 0 0 3 0 0 0 9 COG1462(Uncharacterized protein involved in formation of curli polymers) 108 5 7 9 1 5 11 73 10 9 31 18 14 17 12 20 11 8 27 5 1 4 12 5 5 32 14 7 7 26 5 24 22 8 16 12 10 28 6 11 0 5 0 0 0 0 0 0 0 0 0 6 0 0 0 8 COG3385(FOG: Transposase and inactivated derivatives) 267 22 11 3 1 2 2 0 2 0 4 5 0 6 0 2 8 18 8 3 3 5 7 5 3 10 7 5 5 2 12 0 11 0 5 6 78 131 6 2 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2170(Uncharacterized conserved protein) 113 10 14 22 2 1 4 5 0 0 0 0 2 2 7 0 2 1 2 6 25 5 28 20 35 3 8 16 16 12 24 26 6 10 11 75 3 95 35 5 8 2 0 0 0 0 0 0 0 0 0 4 0 1 0 6 COG4243(Predicted membrane protein) 30 13 4 25 2 8 4 2 1 0 1 0 1 1 2 1 7 31 4 3 32 12 28 19 19 56 2 6 19 15 29 23 5 4 10 4 23 181 41 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG09488() 4 18 32 25 10 2 16 9 9 6 5 3 4 15 14 4 11 10 7 14 10 17 19 12 10 11 17 17 4 3 11 29 22 4 50 48 11 66 15 43 10 8 0 0 0 0 0 0 0 0 2 6 0 0 0 9 COG3677(Transposase and inactivated derivatives) 238 33 12 17 5 3 6 5 6 7 3 1 0 17 8 6 4 5 6 8 2 11 4 4 7 12 6 7 5 0 5 10 5 5 22 19 28 76 7 15 7 2 0 0 0 0 0 0 0 0 0 1 0 0 0 21 NOG10027() 12 28 69 25 4 1 1 9 6 2 4 8 5 6 12 7 1 4 11 19 14 9 24 9 12 1 14 15 7 3 3 34 17 22 48 83 6 39 6 26 5 11 0 0 0 0 0 0 0 0 0 8 0 0 0 20 COG0371(Glycerol dehydrogenase and related enzymes) 56 18 26 26 2 6 5 0 0 0 0 0 4 2 8 2 4 8 2 6 14 15 53 26 36 30 17 12 26 21 20 34 8 8 43 27 14 32 25 11 8 2 0 0 0 0 0 0 0 0 0 4 0 0 0 8 COG3892(Uncharacterized protein conserved in bacteria) 104 12 29 13 4 2 11 5 7 2 0 5 3 11 6 14 4 6 9 12 17 6 19 24 17 1 11 30 14 0 12 26 27 24 16 25 34 9 20 15 18 15 0 0 0 0 0 0 0 0 0 10 0 0 2 17 COG1202(Superfamily II helicase, archaea-specific) 19 18 35 14 1 10 8 4 4 5 0 3 0 1 6 2 8 23 8 16 25 21 30 19 20 57 13 21 10 3 17 44 26 12 6 24 10 89 15 9 4 3 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG25716() 10 3 15 13 1 17 1 6 0 5 6 5 6 33 5 12 13 3 31 12 15 26 5 3 2 38 3 10 6 1 9 11 1 6 8 13 7 270 7 10 5 5 0 0 0 0 0 0 0 0 0 8 0 0 0 1 COG1843(Flagellar hook capping protein) 123 21 14 16 4 18 5 6 3 0 3 5 7 19 4 2 9 3 7 6 22 7 19 9 15 5 19 11 7 3 4 24 17 11 30 19 6 106 9 13 6 10 0 0 0 0 0 0 0 0 0 7 0 0 0 13 COG1847(Predicted RNA-binding protein) 11 7 16 8 0 0 8 1 2 2 0 5 2 9 6 17 38 57 8 7 6 9 24 8 6 104 15 10 6 1 9 9 19 11 12 51 11 97 16 4 12 6 0 0 0 0 0 0 0 0 0 8 0 0 0 9 NOG10322(Lycopene beta cyclase) 43 16 37 39 1 7 1 4 0 0 0 0 1 0 0 0 0 0 1 16 44 25 55 51 59 14 1 14 35 35 43 16 2 2 12 2 0 49 26 1 0 4 0 0 0 0 0 0 0 0 0 9 0 1 0 1 COG4154(Fucose dissimilation pathway protein FucU) 71 40 36 47 0 6 16 11 5 3 0 9 1 5 4 2 4 12 10 13 2 8 20 12 10 3 22 12 6 6 14 18 12 20 37 44 14 52 20 15 5 6 0 0 0 0 0 0 0 0 0 7 0 0 0 7 COG4773(Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid) 493 21 15 10 0 1 2 0 2 2 3 0 6 8 0 2 0 4 5 0 2 1 9 6 2 2 4 4 4 1 12 2 2 4 5 2 15 4 2 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3227(Zinc metalloprotease (elastase)) 338 6 7 6 0 2 1 6 1 7 7 6 2 19 2 4 4 4 4 8 3 2 8 2 0 13 8 6 3 10 0 8 6 9 2 1 11 83 3 15 11 2 0 0 0 0 0 0 0 0 0 5 0 0 0 19 COG2269(Truncated, possibly inactive, lysyl-tRNA synthetase (class II)) 8 17 19 12 3 2 3 6 9 12 14 3 4 21 4 9 6 8 17 10 15 3 26 9 12 31 14 11 2 1 12 13 14 12 26 41 42 161 9 8 3 0 2 0 0 0 0 0 0 0 0 3 0 0 2 4 COG0853(Aspartate 1-decarboxylase) 42 16 13 13 13 6 16 10 6 6 12 4 4 15 10 4 18 4 14 8 8 20 12 10 18 11 7 8 9 1 1 28 11 4 64 27 34 88 11 24 8 10 0 1 0 0 0 0 0 0 0 2 0 0 0 12 COG2371(Urease accessory protein UreE) 89 27 24 54 1 7 6 8 0 2 5 2 7 18 6 1 7 2 9 6 22 15 40 31 25 4 17 8 20 11 23 6 7 7 43 17 4 31 15 6 2 6 0 0 0 0 1 0 0 0 0 4 0 2 0 14 NOG06393() 3 10 58 13 21 5 23 6 19 5 11 12 2 2 14 6 5 9 7 13 3 11 23 8 12 6 11 14 7 3 6 30 27 8 58 37 20 48 13 33 6 10 0 0 0 0 0 0 0 0 0 11 0 0 0 9 COG0831(Urea amidohydrolase (urease) gamma subunit) 61 36 23 46 6 12 8 5 1 6 6 1 7 14 12 3 8 6 9 13 25 8 31 23 25 4 12 6 15 7 18 4 13 10 19 20 7 80 20 11 0 2 0 0 0 0 1 0 0 0 0 2 0 0 0 12 COG2242(Precorrin-6B methylase 2) 97 20 21 36 3 5 3 9 4 3 2 1 2 27 4 7 4 2 3 4 21 23 25 20 33 10 2 12 16 18 7 20 10 6 30 22 7 53 28 15 10 5 0 0 0 3 0 0 0 0 0 2 0 0 0 3 COG3740(Phage head maturation protease) 6 3 3 2 3 2 2 27 7 3 26 1 18 13 4 5 4 10 30 11 2 2 5 8 6 16 18 6 4 19 4 7 10 3 8 9 14 316 3 2 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 11 COG4445(Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA) 47 16 16 16 9 3 2 8 8 15 7 2 2 15 4 3 0 4 23 7 29 3 29 10 21 7 7 9 10 13 19 26 17 2 24 16 12 149 15 16 2 2 0 0 0 0 0 0 0 2 0 7 0 0 0 3 COG0562(UDP-galactopyranose mutase) 56 13 18 14 2 5 6 7 1 2 1 5 1 7 0 5 18 20 4 19 18 8 28 16 6 141 4 8 10 9 9 14 19 15 18 31 8 37 19 10 6 8 0 0 0 0 1 0 0 0 0 1 0 0 0 9 COG5322(Predicted dehydrogenase) 48 19 14 26 3 5 1 5 1 1 0 1 6 6 2 0 9 6 4 6 31 14 44 31 43 6 10 19 15 23 32 26 6 9 11 15 3 93 42 5 3 2 0 0 0 0 0 0 0 0 0 9 0 0 0 1 COG0826(Collagenase and related proteases) 279 15 17 12 5 0 3 2 1 0 2 0 0 7 2 5 16 9 6 3 4 3 10 3 6 17 23 4 3 6 4 0 2 0 4 3 44 107 17 7 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG4370(Uncharacterized protein conserved in bacteria) 50 7 2 43 4 9 3 1 0 0 0 0 2 2 0 0 0 0 0 2 44 7 67 40 27 5 2 25 38 34 35 31 0 6 10 0 2 81 63 2 0 2 0 0 0 0 0 0 0 0 0 7 0 0 0 2 NOG39267() 103 6 41 9 1 9 2 20 3 2 23 3 12 6 8 7 10 18 6 12 13 4 11 12 8 37 37 6 6 6 7 26 31 10 6 15 51 25 10 6 12 0 0 0 0 0 0 0 0 0 0 1 0 0 0 14 COG3960(Glyoxylate carboligase) 293 17 23 18 2 2 14 4 2 2 2 4 3 13 1 2 7 6 5 7 5 4 11 5 8 17 2 3 8 4 11 26 12 2 8 27 4 39 6 4 2 4 0 0 0 0 0 0 0 0 0 2 0 1 0 13 COG2860(Predicted membrane protein) 222 15 15 9 1 1 0 1 1 4 4 3 0 14 4 4 25 34 7 1 0 2 3 0 0 74 2 1 1 3 0 1 1 0 6 4 10 181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1476(Predicted transcriptional regulators) 8 26 33 15 2 1 12 9 6 6 10 15 7 16 16 10 0 10 12 18 12 5 20 15 9 11 9 8 4 5 4 33 26 9 66 61 19 43 19 19 8 8 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG06411(Tonb-Dependent receptor) 14 25 39 21 35 5 27 24 13 14 6 8 2 11 8 6 10 8 6 12 3 20 35 13 17 6 10 12 8 1 6 20 23 12 35 55 9 21 5 18 13 3 0 0 0 0 0 0 0 0 2 4 0 0 0 9 NOG26238() 7 7 19 14 2 4 2 13 8 1 13 4 7 25 5 12 12 13 42 12 12 12 10 5 6 26 24 18 7 9 5 29 13 11 61 32 2 93 7 20 11 3 0 2 0 0 0 0 0 0 0 6 0 0 2 5 COG0598(Mg2+ and Co2+ transporters) 190 3 4 1 2 0 3 0 1 5 7 4 2 25 8 6 45 18 7 6 6 2 1 1 0 69 7 0 3 0 1 1 1 2 2 4 33 173 4 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3772(Phage-related lysozyme (muraminidase)) 16 2 2 1 0 1 3 47 9 4 18 4 7 9 4 5 11 15 25 4 2 4 5 6 7 105 16 6 5 9 4 2 10 5 5 2 8 247 1 2 3 2 0 0 0 0 0 0 0 0 0 5 0 0 0 3 NOG20085() 1 15 12 7 5 3 10 28 5 13 11 4 12 12 6 4 4 14 13 1 13 29 41 23 18 21 34 4 16 56 10 13 13 0 7 11 7 114 2 8 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 23 NOG13653() 18 50 58 36 2 2 15 8 10 5 5 0 8 12 2 5 2 0 19 12 16 14 26 5 16 4 10 7 13 4 5 25 23 18 59 58 6 16 10 23 8 3 0 0 0 0 0 1 0 0 0 5 0 0 0 7 COG4643(Uncharacterized protein conserved in bacteria) 131 19 22 14 0 0 1 9 3 4 14 1 6 13 0 1 5 2 11 2 5 11 11 16 8 4 12 13 8 16 6 8 8 2 0 8 9 227 8 0 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 7 COG1455(Phosphotransferase system cellobiose-specific component IIC) 553 14 7 0 0 0 0 0 0 0 3 0 0 1 0 0 2 7 4 0 0 0 2 2 5 23 3 0 0 3 2 0 0 0 0 0 8 8 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2924(Fe-S cluster protector protein) 72 54 49 36 1 3 10 2 2 3 6 7 8 22 3 5 15 9 12 8 5 10 14 15 11 13 7 4 7 1 2 19 14 8 43 32 11 61 6 14 6 3 0 0 0 0 0 0 0 2 0 8 0 0 0 6 COG1040(Predicted amidophosphoribosyltransferases) 89 5 6 3 3 6 3 7 9 7 12 0 8 47 6 6 37 39 16 0 2 2 5 2 4 58 6 2 6 2 4 6 1 5 8 12 53 147 8 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4276(Uncharacterized conserved protein) 3 24 38 18 9 1 6 7 8 5 3 11 0 7 4 2 3 3 2 15 33 27 19 17 4 39 20 20 3 4 9 19 26 17 47 51 8 44 13 15 19 1 0 0 0 0 0 0 0 1 0 12 0 0 0 11 COG1247(Sortase and related acyltransferases) 107 14 13 9 2 5 8 4 3 0 4 9 0 15 12 14 10 18 14 16 11 6 5 5 7 38 11 3 2 6 3 14 15 14 9 30 6 127 10 11 4 4 0 0 0 0 0 0 0 0 0 4 0 0 0 26 COG3662(Uncharacterized protein conserved in bacteria) 63 6 8 5 0 0 4 3 4 2 1 5 2 11 7 5 15 49 9 11 18 12 13 4 9 85 6 12 12 0 4 8 10 10 15 18 2 165 7 3 6 0 0 0 0 0 0 0 0 0 0 6 0 0 0 13 NOG06142() 21 34 32 22 6 5 11 11 3 0 3 6 3 13 10 8 9 21 13 5 14 17 26 16 17 0 12 18 13 4 22 25 23 20 59 36 3 0 15 21 8 8 0 1 0 1 0 0 0 0 0 12 0 0 0 20 COG1948(ERCC4-type nuclease) 80 9 29 15 9 8 4 6 7 0 0 1 5 9 10 5 8 11 4 18 35 25 46 20 18 8 1 22 10 14 4 26 13 8 14 24 42 18 18 21 8 6 0 0 0 0 0 0 0 0 0 4 0 0 0 4 COG0433(Predicted ATPase) 117 13 27 18 1 1 1 2 1 0 2 4 2 12 4 3 26 22 5 11 11 2 6 6 6 33 9 2 4 0 4 13 9 1 8 23 112 86 1 3 5 6 0 0 0 0 0 0 0 0 0 2 0 0 0 22 COG1876(D-alanyl-D-alanine carboxypeptidase) 59 16 12 15 19 4 6 13 3 6 7 0 2 17 9 1 13 13 11 1 27 11 32 17 19 14 5 5 6 19 9 22 11 7 28 22 12 94 27 10 3 8 0 0 0 2 0 0 0 0 0 7 0 0 0 1 COG3961(Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes) 241 9 14 9 1 0 1 0 1 11 7 5 2 16 6 9 4 5 5 11 6 4 13 8 0 4 6 10 4 0 9 15 11 2 14 12 7 128 4 9 3 6 0 0 0 0 0 0 0 0 0 4 0 0 0 8 COG3150(Predicted esterase) 141 56 47 24 4 1 12 12 3 10 11 3 0 5 6 5 7 2 4 8 5 7 16 8 14 6 13 5 6 8 3 22 18 14 56 16 12 2 17 13 6 1 0 0 0 0 0 0 0 0 0 5 0 0 0 10 NOG09316() 19 52 58 29 2 6 18 3 8 5 4 5 4 9 4 11 6 6 17 16 3 16 18 9 15 47 16 10 13 4 5 19 19 19 40 42 0 14 9 25 3 4 0 0 0 0 0 0 0 0 0 6 0 0 0 4 COG2064(Flp pilus assembly protein TadC) 127 1 1 3 0 0 1 0 0 0 4 0 2 6 6 2 11 12 5 8 2 6 9 6 2 16 5 3 5 5 1 21 15 8 2 3 50 242 7 11 11 6 0 0 0 0 0 0 0 0 0 2 0 0 0 14 COG3153(Predicted acetyltransferase) 151 11 14 10 1 4 2 7 6 8 9 1 5 13 4 7 10 8 14 8 2 0 9 6 7 12 5 9 4 0 2 14 15 14 29 12 5 155 6 16 2 10 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG5651(PPE-repeat proteins) 3 18 94 20 22 9 3 14 3 0 10 0 4 13 6 6 7 9 8 4 3 25 28 8 3 87 2 3 5 9 1 8 4 2 4 12 18 117 7 4 8 8 0 0 0 0 0 0 0 0 0 5 0 0 0 13 COG1679(Uncharacterized conserved protein) 67 18 27 23 1 2 1 0 2 6 1 8 7 16 2 8 6 5 1 13 5 27 26 15 10 19 16 10 14 5 11 27 36 13 33 22 6 21 7 26 20 7 0 0 0 0 0 0 0 0 0 6 0 0 0 40 NOG12222() 10 14 18 16 0 1 2 11 0 1 0 4 3 1 2 2 17 11 11 7 10 10 10 7 10 14 9 6 16 3 7 13 15 15 18 32 8 271 10 4 3 0 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG3508(Homogentisate 1,2-dioxygenase) 142 11 48 20 8 3 2 11 7 2 4 2 5 8 4 2 3 7 10 6 7 11 17 13 12 20 7 7 12 3 1 17 23 5 10 30 19 69 17 14 3 2 0 0 0 0 0 0 0 0 0 4 0 0 0 6 COG2826(Transposase and inactivated derivatives, IS30 family) 220 21 2 1 0 0 0 3 1 0 4 0 2 6 0 3 5 2 9 3 3 10 9 2 7 12 1 7 2 0 4 0 0 0 6 2 80 203 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG0572(Uridine kinase) 67 15 57 21 7 4 5 6 1 3 3 3 2 6 2 6 17 6 8 11 14 15 41 22 20 20 12 14 7 7 4 30 5 7 34 43 22 28 13 11 5 6 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2453(Predicted protein-tyrosine phosphatase) 167 18 34 24 10 22 5 6 6 3 4 2 8 7 4 3 7 10 7 13 12 2 16 7 7 19 11 6 4 31 8 14 13 10 11 24 7 30 10 19 0 2 0 0 0 0 0 0 0 0 0 1 1 0 0 6 COG4988(ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components) 188 18 8 9 2 2 2 2 1 0 0 0 0 4 2 4 18 12 0 7 9 6 9 5 18 36 12 4 5 2 0 3 5 2 11 27 48 137 4 3 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13927(Biosynthesis protein) 9 14 15 18 4 1 4 31 7 7 2 5 2 4 7 4 6 16 10 22 8 13 25 9 16 119 11 12 14 5 20 21 21 23 27 25 11 8 14 8 4 7 0 0 0 0 0 0 0 0 0 7 0 0 0 13 NOG08360() 26 18 67 29 4 4 6 17 6 6 8 6 5 11 10 6 8 2 10 10 21 14 27 9 16 4 12 9 16 4 10 19 18 12 58 50 2 26 5 21 1 1 0 0 0 0 0 2 0 0 0 10 0 0 0 3 NOG13351() 60 52 61 40 2 4 13 6 2 3 3 4 2 5 10 11 6 2 6 10 10 5 31 13 11 0 8 8 12 9 5 24 24 11 44 24 10 25 11 15 15 1 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1392(Phosphate transport regulator (distant homolog of PhoU)) 110 22 27 20 0 0 1 0 6 3 2 5 2 21 6 3 13 7 18 11 7 3 8 5 11 42 18 4 9 3 6 18 17 17 43 49 20 0 11 18 10 12 0 0 0 0 0 0 0 0 0 10 0 0 0 11 COG2878(Predicted NADH:ubiquinone oxidoreductase, subunit RnfB) 99 11 26 4 3 1 2 15 5 2 3 15 2 27 17 10 17 15 14 10 7 12 8 6 5 3 12 4 4 4 5 9 3 2 16 26 27 127 3 11 3 4 0 0 2 0 0 0 0 0 0 0 0 0 0 28 NOG18336() 23 50 63 30 4 1 9 20 6 13 4 4 10 24 9 5 6 0 6 6 14 18 33 19 12 8 19 3 17 8 11 22 23 12 36 28 3 6 6 9 7 11 0 0 2 0 0 0 0 0 0 5 0 0 0 3 COG1773(Rubredoxin) 96 20 9 24 0 7 9 2 1 9 3 1 6 22 4 5 6 0 6 5 27 27 34 11 25 3 7 12 15 11 20 24 10 2 18 17 4 73 32 2 1 13 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG16972() 49 42 86 50 3 2 8 9 2 7 2 3 1 24 8 3 14 2 5 8 2 6 17 9 12 4 10 15 3 1 5 17 22 12 47 55 4 9 7 15 5 11 0 0 0 0 0 0 0 0 0 8 0 0 0 2 NOG16088(Parallel beta-helix repeats) 91 13 15 13 0 0 2 12 10 2 0 9 6 15 13 23 2 4 4 13 17 12 13 13 7 4 16 26 15 0 10 23 26 16 22 60 6 0 14 13 12 14 0 0 0 0 0 0 0 0 0 7 0 0 0 33 COG2831(Hemolysin activation/secretion protein) 265 6 13 10 0 3 2 11 1 2 6 3 0 25 2 11 35 40 13 7 2 4 7 7 7 28 8 2 5 1 3 10 7 4 8 9 11 33 0 4 2 0 0 0 0 0 0 0 0 0 0 1 0 1 0 7 COG2835(Uncharacterized conserved protein) 84 34 28 16 3 7 12 10 4 12 8 6 5 19 5 8 10 9 5 8 4 8 10 10 9 32 3 5 8 3 2 18 13 13 32 36 18 65 7 15 3 5 0 0 0 0 0 0 0 0 0 10 0 0 0 4 COG4651(Kef-type K+ transport system, predicted NAD-binding component) 128 10 6 5 3 2 0 0 0 0 0 0 4 7 6 1 8 19 6 4 4 7 15 5 1 6 2 5 5 0 2 2 2 7 6 4 2 325 3 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3454(Metal-dependent hydrolase involved in phosphonate metabolism) 40 41 16 43 8 35 42 0 0 0 0 0 0 3 2 3 2 0 3 11 2 16 20 17 12 19 0 0 1 1 0 1 0 0 0 3 3 276 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG04781() 112 29 17 13 5 1 13 4 6 4 4 0 8 15 3 5 5 2 14 1 6 8 9 10 12 25 7 6 9 4 5 32 13 11 28 33 17 71 9 23 6 11 0 0 0 0 0 0 0 0 0 5 0 0 0 2 NOG21817() 206 20 13 14 2 0 2 4 0 1 2 5 0 3 6 6 21 11 8 4 7 6 15 10 9 17 11 17 8 2 9 14 11 8 43 29 5 20 14 11 4 2 0 0 0 0 0 0 0 0 0 3 0 1 0 19 NOG14359(Cytochrome c, class I protein) 50 19 22 18 2 3 2 7 5 12 11 5 6 25 2 6 11 11 3 12 5 2 8 8 11 7 10 10 5 0 3 14 20 17 48 11 21 162 6 10 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG1453(Predicted oxidoreductases of the aldo/keto reductase family) 42 26 4 39 3 7 1 0 1 1 0 0 0 3 0 1 0 0 2 6 47 14 54 22 36 1 4 10 28 49 40 31 8 1 13 3 0 66 34 5 2 0 2 0 0 0 0 0 0 0 0 10 0 0 0 5 NOG27762() 14 55 57 43 5 6 15 15 7 9 1 6 4 16 7 6 1 0 7 15 14 13 29 13 8 0 6 19 16 3 7 25 28 9 76 33 2 0 2 14 3 3 0 0 0 2 0 0 0 0 0 1 0 0 0 5 COG2813(16S RNA G1207 methylase RsmC) 133 21 7 8 0 3 0 2 3 13 13 4 2 31 10 6 7 14 14 4 4 5 6 1 5 15 5 7 2 0 5 13 8 3 27 27 31 104 9 23 7 6 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG0267(Ribosomal protein L33) 24 10 9 22 10 5 6 11 3 2 4 4 3 20 5 6 12 13 8 13 15 5 24 21 13 8 8 14 12 10 16 20 19 16 47 21 9 90 27 11 11 2 0 0 0 0 0 0 0 0 0 2 0 0 0 9 NOG14997(Chaperone protein htpG) 5 16 27 21 16 2 22 16 12 2 18 5 2 9 15 7 4 7 16 15 4 21 17 8 12 10 13 8 1 1 2 30 22 7 54 55 5 34 8 44 6 2 0 0 0 0 0 0 0 0 0 8 0 0 0 10 COG2311(Predicted membrane protein) 54 8 38 14 6 1 8 14 2 0 5 0 5 20 2 5 18 13 8 6 3 10 19 12 6 16 13 10 7 3 2 22 16 15 23 32 9 105 11 9 12 6 0 1 0 0 0 0 0 0 2 9 0 0 0 15 COG2138(Uncharacterized conserved protein) 56 11 27 47 0 4 2 0 3 6 2 2 4 17 0 5 6 4 8 0 18 24 40 22 42 13 10 13 12 30 25 16 6 3 10 12 8 63 20 3 0 4 0 0 0 0 0 0 2 0 0 5 2 2 0 6 COG1988(Predicted membrane-bound metal-dependent hydrolases) 42 30 48 17 4 6 2 11 13 7 5 3 6 10 9 9 3 6 8 14 11 14 19 6 15 6 16 15 2 6 2 17 16 8 29 25 14 86 6 20 2 13 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG0748(Putative heme iron utilization protein) 89 8 12 19 2 4 2 2 1 0 2 0 5 5 0 1 2 0 5 5 11 6 20 15 13 1 6 10 15 5 17 56 44 11 46 25 5 44 35 18 14 9 0 0 0 0 0 0 0 0 0 9 0 0 0 13 NOG04749(Magnesium-Protoporphyrin IX monomethyl ester protein) 28 10 5 25 6 13 6 6 1 6 2 0 3 11 3 1 8 4 12 10 20 7 33 21 27 13 7 13 18 13 24 24 14 12 23 11 0 98 22 18 0 6 2 0 0 0 0 0 0 0 0 14 1 0 0 10 COG1023(Predicted 6-phosphogluconate dehydrogenase) 4 6 8 10 0 1 2 11 8 4 2 4 5 9 1 10 18 13 4 41 5 6 9 7 2 52 18 3 1 8 0 15 17 23 8 5 19 79 45 5 40 0 0 0 0 0 0 0 0 0 0 1 0 0 0 82 NOG38388() 20 8 5 12 2 2 2 10 2 2 0 0 10 0 0 0 0 2 1 13 19 5 58 37 26 57 10 22 47 48 31 13 12 8 7 5 0 23 35 2 7 11 0 0 0 0 0 0 0 0 0 7 0 0 0 29 COG1241(Predicted ATPase involved in replication control, Cdc46/Mcm family) 6 22 54 16 10 7 0 10 6 9 0 5 0 20 21 10 3 0 9 15 8 17 33 10 12 27 13 14 12 17 3 19 34 19 0 28 41 7 9 19 10 10 0 0 0 0 0 0 0 0 0 4 0 4 0 17 COG2503(Predicted secreted acid phosphatase) 19 65 60 42 4 3 13 7 5 6 2 4 4 15 15 7 1 0 4 6 19 8 24 9 13 3 5 12 11 6 3 24 10 8 72 32 5 0 14 11 11 11 0 0 0 0 0 0 0 0 0 9 1 0 0 7 NOG07994() 9 17 13 13 3 2 8 24 12 7 7 4 6 11 12 8 2 6 9 16 10 11 26 14 16 11 12 20 22 26 12 26 25 33 30 26 4 18 30 14 11 2 0 0 0 0 0 0 0 0 0 2 0 0 0 20 COG4569(Acetaldehyde dehydrogenase (acetylating)) 361 14 2 4 0 1 2 4 8 7 0 7 5 25 6 3 6 12 10 11 3 7 1 2 1 3 6 0 0 1 0 10 3 6 8 10 2 43 4 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG36609() 9 58 54 48 4 2 16 7 3 5 4 3 1 20 15 2 0 0 4 14 2 11 21 16 14 0 15 15 18 5 8 31 23 13 52 33 2 0 17 22 5 4 0 0 0 0 0 0 0 0 0 7 0 0 0 5 NOG26302() 8 7 10 12 17 1 19 11 9 4 7 9 9 7 5 5 8 9 13 2 11 18 11 4 5 6 9 14 8 5 11 40 16 19 83 43 9 5 19 56 12 9 0 0 0 0 0 0 0 0 0 16 0 0 0 7 COG3387(Glucoamylase and related glycosyl hydrolases) 182 15 3 12 18 2 18 10 3 1 11 0 5 10 2 2 4 20 4 0 6 5 20 4 13 8 7 1 3 0 12 5 4 9 10 3 29 132 3 4 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 2 COG1874(Beta-galactosidase) 104 11 6 5 7 5 4 8 5 8 13 4 6 33 2 7 5 9 28 7 3 0 4 4 9 8 22 13 6 12 6 7 13 18 47 37 11 35 12 19 11 11 0 0 0 0 0 0 0 0 0 9 0 0 0 13 NOG18956() 2 4 7 1 0 1 2 41 39 24 12 24 31 21 6 9 17 16 28 36 4 2 17 3 3 114 23 6 6 5 2 9 10 2 10 15 6 20 8 2 6 3 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG2099(Precorrin-6x reductase) 102 10 10 22 0 8 6 5 0 6 4 2 2 13 2 4 0 0 5 7 14 16 26 22 25 0 12 9 20 13 31 31 16 6 15 12 0 67 27 12 4 6 0 0 0 1 0 0 0 0 0 8 0 0 0 5 COG2173(D-alanyl-D-alanine dipeptidase) 127 12 21 20 5 5 4 0 4 3 1 3 1 12 2 4 2 11 7 9 27 13 23 17 26 13 8 21 10 16 16 22 7 8 11 18 11 43 22 8 1 3 0 0 0 0 0 0 0 0 0 6 0 0 0 3 NOG18724() 28 17 23 24 0 4 6 25 12 7 10 19 10 9 4 9 16 6 6 13 7 4 18 8 12 0 28 3 10 0 7 10 7 4 51 64 14 67 10 14 1 3 0 0 0 0 0 0 0 0 0 1 0 0 0 14 COG1030(Membrane-bound serine protease (ClpP class)) 69 27 72 15 1 2 2 2 4 4 4 3 5 2 7 1 6 9 7 11 10 14 27 12 4 65 4 18 8 4 4 3 8 4 3 35 9 91 1 13 3 4 0 0 0 0 0 0 0 0 0 5 0 0 0 3 NOG16697() 11 15 20 13 2 11 2 16 2 2 8 1 6 33 9 12 3 10 35 16 14 21 13 3 7 22 9 15 4 17 7 10 12 2 7 22 8 154 3 5 3 10 0 0 0 0 0 0 2 0 0 3 0 0 0 3 COG2916(DNA-binding protein H-NS) 576 2 6 0 0 0 1 0 0 0 0 0 0 1 0 0 2 1 2 0 0 0 0 0 0 3 2 0 0 0 1 0 0 0 0 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1387(Histidinol phosphatase and related hydrolases of the PHP family) 201 11 19 5 1 2 2 2 0 2 2 5 4 11 4 0 9 6 4 4 6 21 11 1 3 18 5 8 5 2 6 12 11 1 4 22 21 120 6 6 4 6 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG17243() 26 48 67 50 4 6 15 14 1 5 1 2 18 15 5 2 0 0 4 8 3 6 18 10 11 1 9 11 10 4 10 29 13 16 54 34 6 15 8 17 2 13 0 0 0 0 0 0 0 0 0 8 0 0 0 2 NOG14313() 14 9 20 28 3 3 3 12 1 3 0 4 4 1 10 3 21 24 9 11 7 6 18 12 11 53 8 18 13 2 5 24 21 11 41 51 8 47 10 11 13 10 0 0 0 0 0 0 0 0 0 3 0 0 0 15 COG0818(Diacylglycerol kinase) 133 13 5 22 3 5 7 1 3 1 5 2 0 7 2 1 14 16 7 6 19 8 19 14 18 17 6 9 9 15 8 10 3 3 18 14 20 110 13 6 0 4 0 0 0 0 0 0 0 0 0 0 1 0 0 3 COG1111(ERCC4-like helicases) 8 16 43 25 5 5 6 0 2 10 2 1 2 7 8 6 6 2 0 7 3 25 31 26 1 23 14 20 6 4 14 23 16 19 20 35 38 38 15 22 10 11 0 0 0 0 0 0 0 0 0 4 0 0 0 20 COG3128(Uncharacterized iron-regulated protein) 112 21 34 14 0 6 3 17 3 5 0 4 0 4 4 1 7 12 1 10 21 11 24 20 11 25 11 14 18 28 9 29 7 6 10 8 7 8 25 9 9 6 0 0 0 0 0 0 0 0 0 1 0 0 0 24 NOG11148() 11 8 10 7 0 1 10 4 2 3 5 3 4 7 4 13 20 49 15 17 10 8 34 8 15 55 24 11 8 1 13 16 15 15 21 30 4 59 7 4 5 5 0 0 0 0 0 0 0 0 0 4 0 0 0 33 NOG17015() 10 16 23 13 9 0 17 5 15 0 3 9 2 17 4 2 4 7 7 7 14 13 16 7 14 6 11 16 17 1 19 18 15 17 58 44 3 57 11 24 14 2 2 1 0 0 0 0 0 0 0 8 0 0 0 20 COG3342(Uncharacterized conserved protein) 77 13 44 17 5 5 4 5 5 4 0 1 8 19 7 6 13 7 8 17 12 16 19 6 12 3 27 3 10 2 1 13 6 2 31 36 2 59 18 21 4 2 2 0 0 0 0 0 0 0 0 2 0 0 0 22 COG2353(Uncharacterized conserved protein) 184 15 27 17 2 4 4 9 9 5 5 1 2 18 0 0 20 9 3 5 10 2 18 6 7 45 3 3 1 2 4 14 2 6 13 17 18 68 4 4 2 0 0 1 1 0 0 0 0 0 0 2 0 0 0 3 NOG37783() 15 10 5 23 2 3 2 0 0 1 0 0 0 0 0 0 0 0 0 9 43 24 84 50 44 47 6 30 42 70 38 1 1 2 6 0 0 4 16 0 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 10 NOG19164() 18 21 35 41 1 0 8 12 4 1 3 3 6 13 3 4 14 7 5 7 3 18 18 9 9 14 7 8 10 1 14 13 14 8 43 58 13 66 6 13 9 3 0 0 0 0 0 1 0 0 0 8 0 0 0 22 COG3384(Uncharacterized conserved protein) 217 8 17 5 2 1 0 0 0 2 0 7 0 16 1 3 22 9 2 18 11 13 11 7 3 28 4 12 5 11 9 23 19 7 4 38 13 3 4 9 11 3 0 0 0 0 0 0 0 0 0 4 0 0 0 10 COG1558(Flagellar basal body rod protein) 104 16 14 19 2 18 8 8 4 0 5 4 8 22 2 4 13 2 8 8 16 4 14 8 13 3 16 9 7 2 1 17 10 11 31 22 12 87 9 7 5 1 0 0 0 0 0 0 0 0 0 7 0 0 0 10 COG4126(Hydantoin racemase) 112 13 18 24 4 12 4 5 6 1 4 3 9 25 8 3 10 1 8 15 17 8 17 10 11 6 8 12 8 5 13 16 11 12 33 25 2 40 13 13 3 11 0 0 0 0 0 0 0 2 0 3 0 0 0 7 NOG19129() 17 41 66 35 7 0 12 4 2 1 3 4 2 9 4 7 0 2 2 10 8 24 28 10 8 0 7 13 8 3 6 28 18 2 77 34 3 6 23 30 6 6 0 0 0 0 0 0 0 0 0 7 0 0 0 7 COG4208(ABC-type sulfate transport system, permease component) 343 7 5 5 2 0 6 6 8 3 2 3 2 5 3 3 4 6 4 0 3 3 10 4 8 13 2 12 7 1 9 11 1 12 8 8 2 15 5 12 2 10 0 0 0 0 0 0 1 0 0 10 0 0 0 2 COG5257(Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)) 106 21 38 18 0 2 1 3 1 3 0 1 1 9 10 11 3 2 7 10 7 25 17 17 12 32 3 8 7 6 9 13 22 11 9 38 38 11 2 8 15 12 0 0 0 0 0 0 0 0 0 5 0 0 0 13 COG1922(Teichoic acid biosynthesis proteins) 66 9 10 12 5 0 6 0 3 0 8 4 1 25 6 12 12 4 3 16 22 7 17 7 17 7 19 15 8 2 7 13 8 4 10 31 16 112 24 4 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 25 COG4870(Cysteine protease) 1 12 35 10 36 37 9 7 14 3 1 3 5 8 11 7 16 20 18 11 4 10 21 7 8 19 4 4 10 37 11 14 11 8 4 33 8 69 4 20 0 6 0 0 0 0 0 0 0 0 0 4 0 0 0 4 COG1001(Adenine deaminase) 29 31 43 30 0 1 0 2 12 4 12 13 9 14 12 8 10 3 8 8 7 4 8 4 1 23 2 7 2 5 5 33 14 12 17 60 11 68 12 18 3 6 0 0 0 0 0 0 0 0 0 7 0 0 0 6 COG1314(Preprotein translocase subunit SecG) 76 34 44 25 3 1 7 8 8 2 5 3 11 12 2 1 10 2 12 10 9 20 25 23 18 4 8 8 11 8 5 14 16 7 16 26 21 20 17 11 4 5 0 0 0 0 0 0 0 0 0 6 0 0 0 4 COG1479(Uncharacterized conserved protein) 136 8 14 7 5 2 1 0 1 1 1 0 2 7 6 3 4 6 6 4 3 3 8 5 0 44 6 4 3 2 1 9 9 8 24 18 16 186 4 6 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG1934(Uncharacterized protein conserved in bacteria) 106 13 9 10 1 2 3 6 3 0 11 2 7 17 2 10 13 13 14 3 3 1 6 4 6 7 7 4 4 3 9 11 8 8 21 16 13 172 12 9 4 0 0 0 1 0 0 0 0 0 0 4 0 0 0 3 NOG21856() 2 25 144 13 0 0 2 0 0 0 2 2 0 14 8 2 6 0 2 18 27 31 18 10 15 0 12 13 5 3 6 17 12 14 8 34 0 81 2 22 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG4123(Predicted O-methyltransferase) 71 14 18 14 6 6 3 10 5 2 10 3 5 17 4 3 7 4 4 8 6 12 15 6 3 7 14 7 6 1 7 16 18 9 49 33 15 86 14 11 3 13 0 0 0 0 0 0 0 0 0 7 0 0 0 8 NOG07819() 22 14 13 18 2 5 10 7 7 4 3 0 7 22 4 8 2 0 13 8 2 2 13 12 10 2 12 10 7 4 10 25 12 15 64 33 2 88 33 28 6 3 0 0 0 0 0 0 0 1 0 6 0 0 0 11 COG4781(Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase) 11 30 53 23 7 0 15 19 3 4 1 0 7 12 12 4 12 17 17 19 7 14 13 13 14 18 23 13 3 9 6 14 23 19 28 35 4 19 7 7 5 10 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG3898(Uncharacterized membrane-bound protein) 27 9 15 25 5 3 6 6 5 5 8 0 11 17 4 4 2 0 8 4 5 8 4 6 3 1 10 8 11 2 6 23 25 17 46 49 9 95 19 20 13 15 0 0 0 0 0 0 1 0 0 5 0 1 0 12 NOG12939() 14 18 42 19 11 3 12 4 6 1 3 4 0 9 7 5 4 1 11 8 6 16 24 14 12 14 14 9 11 3 10 14 17 24 49 37 2 45 8 29 16 8 0 0 0 0 4 0 0 0 0 4 1 0 0 4 NOG11124() 31 25 31 19 2 8 13 6 6 8 5 4 2 15 2 1 2 4 6 11 10 14 16 6 11 1 14 5 13 2 12 14 24 21 41 42 0 64 17 23 7 3 0 0 0 1 0 0 0 0 0 7 0 0 0 8 COG0163(3-polyprenyl-4-hydroxybenzoate decarboxylase) 101 22 34 16 5 2 2 2 3 3 2 4 2 15 4 4 9 1 5 10 9 11 21 6 5 31 6 3 5 6 3 13 5 4 14 27 23 99 16 6 6 5 0 0 0 0 0 0 0 0 0 3 1 0 1 2 COG1533(DNA repair photolyase) 80 16 29 24 3 5 2 8 1 3 3 2 2 8 9 4 5 4 7 7 0 13 34 18 15 8 14 14 4 6 5 21 14 14 34 20 30 42 13 17 8 7 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2875(Precorrin-4 methylase) 54 17 23 31 2 13 7 4 1 2 1 0 1 8 4 4 0 2 3 10 14 12 17 22 21 16 6 13 16 17 11 25 12 10 18 39 3 47 29 21 2 4 0 0 0 1 0 0 0 0 0 6 0 0 0 7 COG3773(Cell wall hydrolyses involved in spore germination) 5 9 9 19 1 2 7 17 7 4 29 4 17 24 8 6 7 12 15 10 11 5 18 11 12 29 12 8 6 10 2 27 18 11 27 29 5 76 7 15 10 7 0 0 0 0 0 0 0 0 0 2 0 0 0 6 NOG11068() 105 11 9 16 2 9 2 6 5 3 8 4 2 8 4 9 3 4 10 5 5 3 32 9 33 1 8 2 16 11 13 16 10 5 29 19 4 75 23 17 3 7 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG1072(Panthothenate kinase) 45 8 22 6 2 4 6 4 2 9 4 5 1 13 8 7 15 21 10 7 7 0 3 2 1 56 16 10 4 5 3 13 10 8 22 13 14 153 7 10 5 4 0 0 0 0 0 0 0 1 0 3 0 0 0 6 COG2832(Uncharacterized protein conserved in bacteria) 26 17 38 19 3 4 7 4 1 5 7 10 9 10 6 13 6 4 7 18 14 21 25 7 6 2 20 15 7 3 9 17 18 11 11 49 4 53 8 11 8 2 0 0 0 0 0 0 0 0 0 11 0 0 0 27 COG2937(Glycerol-3-phosphate O-acyltransferase) 100 27 22 15 1 3 16 4 3 1 4 2 6 11 0 4 5 0 14 15 5 7 28 6 11 9 15 23 11 3 7 19 8 13 41 26 3 48 7 9 5 2 0 0 0 0 0 0 0 0 0 4 0 2 0 7 NOG06412() 9 12 27 15 6 0 13 7 10 6 7 9 8 5 2 10 5 13 8 9 8 3 2 11 6 10 9 15 5 5 21 23 18 16 63 72 13 7 6 46 12 8 0 0 0 0 0 0 0 0 0 1 0 0 0 11 COG2003(DNA repair proteins) 161 9 2 9 2 8 5 5 3 1 20 3 6 17 0 4 16 24 9 2 4 0 5 0 0 25 4 1 3 2 3 1 1 9 6 1 49 135 0 6 4 2 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG3238(Uncharacterized protein conserved in bacteria) 99 4 5 1 1 2 2 3 0 3 3 1 2 11 5 3 23 34 12 2 1 1 6 5 1 60 2 2 2 0 1 9 7 6 12 5 2 218 1 8 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG2919(Septum formation initiator) 82 12 26 10 3 6 0 6 1 3 0 1 4 11 8 5 14 32 9 0 1 2 1 3 5 58 3 0 1 0 2 4 5 12 17 11 11 188 4 3 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG2905(Predicted signal-transduction protein containing cAMP-binding and CBS domains) 89 14 3 1 1 1 1 2 0 0 3 2 0 3 0 8 46 51 13 0 3 1 1 0 2 39 7 0 2 5 4 2 0 0 3 0 16 237 4 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG14025() 46 46 42 35 5 4 15 7 3 4 8 7 4 6 8 3 3 3 4 13 15 18 24 5 30 2 17 6 15 4 6 27 8 6 39 31 2 8 9 12 5 9 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG3858(Predicted glycosyl hydrolase) 12 21 62 18 0 5 7 0 0 2 4 2 3 6 2 10 12 25 4 12 8 7 21 9 14 49 9 16 7 5 6 14 12 12 14 22 16 90 2 5 8 4 0 0 0 0 0 0 0 0 0 4 0 0 0 10 COG0727(Predicted Fe-S-cluster oxidoreductase) 127 21 14 18 7 1 7 2 9 1 2 3 3 4 2 3 16 8 4 5 11 3 16 13 17 18 7 10 9 16 12 22 21 12 11 21 5 40 15 17 6 4 0 0 0 0 0 0 0 0 0 5 0 0 2 1 COG0585(Uncharacterized conserved protein) 51 13 29 9 4 0 0 2 3 4 19 3 5 18 6 4 2 0 2 6 7 15 15 8 13 5 7 12 1 8 4 15 14 5 8 19 30 140 3 13 12 6 0 0 0 0 0 0 0 0 0 2 0 0 0 28 COG3944(Capsular polysaccharide biosynthesis protein) 311 2 4 3 1 0 0 2 4 4 0 1 0 2 0 3 1 2 4 0 1 4 5 2 4 24 1 2 0 2 0 3 2 0 4 12 2 143 0 8 1 2 0 0 0 0 1 0 0 0 0 3 0 0 0 0 COG4401(Chorismate mutase) 29 10 16 18 1 4 4 9 2 1 2 3 0 9 3 7 16 14 7 12 12 8 26 24 14 39 11 13 13 9 15 12 18 6 9 27 0 84 27 7 2 7 0 0 0 0 0 0 0 0 0 9 0 0 0 8 COG2221(Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits) 189 22 9 7 0 2 2 5 0 8 2 0 0 13 6 1 5 8 12 13 12 12 9 3 2 15 2 1 7 5 0 8 5 6 6 48 12 77 29 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG09693() 20 17 55 9 1 0 10 3 0 0 2 2 7 2 11 12 4 3 4 14 27 18 35 20 11 1 16 28 19 0 16 19 24 17 5 42 1 5 17 12 10 16 0 0 0 0 0 0 0 0 0 10 0 0 0 21 NOG06756(Carboxysome shell polypeptide CsoS3) 23 8 1 12 0 2 4 0 0 0 0 0 0 1 0 0 0 0 0 3 30 8 42 20 41 0 1 4 21 27 16 15 4 3 2 1 0 237 26 2 2 0 0 0 0 0 0 2 0 0 0 4 0 0 0 2 NOG06762() 98 31 27 35 0 4 2 1 0 0 1 1 2 1 6 6 4 13 3 14 6 8 14 12 3 0 14 17 8 1 8 21 29 19 43 23 3 0 28 16 7 9 0 0 0 0 0 0 0 0 0 9 0 0 0 16 COG4889(Predicted helicase) 10 17 27 27 11 4 4 14 8 4 5 3 7 11 2 9 23 12 8 8 16 16 26 16 5 47 2 6 10 2 17 9 14 9 24 28 14 42 10 8 1 2 0 0 0 0 0 0 0 0 0 8 1 0 0 15 NOG24434() 562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0630(Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis) 215 6 19 3 1 0 0 0 0 0 0 1 2 8 2 2 6 1 0 4 4 16 13 11 4 6 13 12 9 3 6 13 25 12 0 6 59 13 3 14 15 10 2 0 0 0 0 0 0 0 0 1 0 0 0 20 COG3306(Glycosyltransferase involved in LPS biosynthesis) 10 6 7 6 1 4 3 14 2 3 18 11 7 9 6 6 23 32 4 9 9 5 27 17 20 46 11 6 13 16 5 18 18 16 25 34 3 13 16 28 2 11 0 0 0 0 0 0 0 0 0 12 0 0 0 8 NOG08491() 52 13 3 31 11 10 1 2 0 1 0 0 0 0 0 0 0 0 0 0 18 17 54 33 51 0 7 8 23 40 32 23 6 2 12 0 0 63 30 4 0 0 0 0 0 0 0 0 0 0 0 6 0 1 0 6 COG2350(Uncharacterized protein conserved in bacteria) 216 12 13 13 3 3 1 4 1 2 2 0 0 23 2 6 6 1 15 5 16 7 15 10 10 4 4 4 12 8 6 13 10 1 5 22 14 50 8 3 1 5 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG0095(Lipoate-protein ligase A) 38 24 25 33 5 4 2 4 0 2 8 1 5 0 0 2 6 2 4 7 21 6 30 19 19 11 8 8 11 15 15 9 2 2 8 5 15 158 10 6 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG1668(ABC-type Na+ efflux pump, permease component) 59 24 55 18 0 1 7 4 5 3 2 7 2 5 6 2 4 7 20 12 4 17 18 12 11 17 7 7 13 1 2 14 18 6 16 20 6 67 5 20 7 11 0 0 0 0 0 0 0 0 0 5 0 0 0 12 COG2182(Maltose-binding periplasmic proteins/domains) 12 8 10 2 3 4 5 0 0 0 0 0 0 17 2 14 17 25 7 9 9 17 33 12 13 60 11 19 18 3 11 7 22 14 13 15 0 34 19 11 24 13 2 0 0 0 1 0 0 0 0 9 0 0 0 33 COG1887(Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC) 92 15 32 25 1 0 3 10 2 7 5 6 5 4 2 0 6 19 6 5 14 8 16 11 8 21 5 8 3 0 11 12 14 21 28 39 8 46 13 13 7 4 0 0 0 0 0 0 0 1 0 2 0 0 0 0 COG4656(Predicted NADH:ubiquinone oxidoreductase, subunit RnfC) 82 16 5 3 2 2 4 1 1 5 17 5 0 4 0 4 13 10 9 4 2 1 4 3 5 25 4 0 0 0 4 4 1 8 4 10 31 255 7 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG04018() 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 44 71 7 1 0 0 0 1 0 207 1 0 0 0 0 1 0 4 0 0 0 214 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3542(Uncharacterized conserved protein) 97 27 20 36 1 3 9 3 1 0 0 2 4 2 0 2 2 1 1 8 21 13 31 25 27 13 4 4 6 10 16 8 10 3 23 22 4 71 15 6 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG3954(Phosphoribulokinase) 82 13 4 18 0 3 4 5 0 3 0 3 1 7 2 4 7 0 2 1 24 9 35 21 19 2 6 7 14 15 10 7 2 5 10 26 22 141 14 2 1 1 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG1399(Predicted metal-binding, possibly nucleic acid-binding protein) 61 4 22 7 3 0 5 5 7 5 5 2 3 10 4 8 35 28 7 1 5 5 7 3 7 93 4 5 2 2 5 6 0 5 6 12 13 125 19 6 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 3 COG5590(Uncharacterized conserved protein) 26 16 20 19 3 8 9 7 5 6 3 3 6 13 4 5 1 2 7 10 6 5 9 8 21 13 15 12 3 1 9 29 17 15 37 31 2 65 19 18 9 15 0 0 1 0 0 0 0 0 0 8 0 0 0 14 COG1366(Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)) 50 15 14 11 5 5 1 5 6 2 8 5 1 12 1 2 8 5 6 5 14 13 24 12 18 20 7 11 10 8 14 13 2 4 6 22 28 115 25 5 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 10 COG3179(Predicted chitinase) 169 0 1 1 1 1 1 20 1 3 30 1 1 7 2 3 19 20 12 5 0 1 0 2 1 129 8 4 1 7 0 8 12 1 1 1 1 58 3 3 5 2 1 0 0 0 0 0 0 0 0 2 0 0 0 5 COG4333(Uncharacterized protein conserved in bacteria) 31 9 9 32 9 7 4 4 3 2 2 5 2 14 8 1 6 0 7 7 15 8 23 17 14 2 7 7 8 12 9 25 23 14 40 18 6 80 21 18 6 3 0 0 0 0 0 0 0 0 0 7 0 0 0 8 NOG14450(3-Oxo-5-Alpha-Steroid 4-dehydrogenase) 11 40 52 25 1 1 12 6 3 11 0 3 4 4 5 4 0 0 2 13 15 15 21 13 10 0 6 7 12 5 8 25 19 11 70 32 1 8 16 29 9 8 0 0 0 0 0 0 0 0 0 7 0 0 0 9 COG1297(Predicted membrane protein) 5 23 81 13 2 1 1 3 2 0 0 3 7 12 6 3 4 2 2 14 19 17 25 7 10 39 14 17 6 11 6 22 12 10 3 19 5 16 11 26 17 8 0 0 0 0 0 0 0 0 0 10 0 0 0 38 COG1161(Predicted GTPases) 62 16 22 30 20 11 1 1 5 6 15 2 6 13 5 3 15 4 9 1 18 11 34 20 10 4 8 18 16 18 19 12 4 3 6 4 14 38 20 9 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 12 COG4952(Predicted sugar isomerase) 17 13 17 23 1 5 10 11 3 7 6 5 3 6 2 2 7 16 8 8 3 3 12 8 9 15 12 15 11 0 5 32 17 15 58 45 2 38 25 22 7 11 0 0 0 0 0 0 0 0 0 9 0 0 0 7 NOG04780() 100 14 19 22 0 10 2 0 6 3 9 1 6 15 6 9 8 2 15 4 9 12 21 14 16 1 13 12 2 5 6 22 22 13 37 16 4 12 19 14 3 3 0 0 0 0 0 0 0 0 0 9 0 0 0 15 NOG07830() 12 55 56 47 5 3 7 13 5 1 6 3 1 9 12 7 0 0 7 16 8 9 30 8 12 1 11 11 7 7 5 16 15 9 61 18 3 23 5 10 4 4 0 0 0 0 0 0 2 1 0 5 0 0 0 0 COG3453(Uncharacterized protein conserved in bacteria) 146 9 18 7 7 2 2 0 1 0 3 0 0 23 7 6 15 8 4 4 3 0 6 2 4 12 6 0 3 0 8 12 9 8 24 18 10 132 4 11 2 3 0 0 0 0 0 0 0 0 0 7 0 0 0 2 COG2247(Putative cell wall-binding domain) 1 21 33 12 7 2 1 2 2 1 0 2 8 6 0 4 18 11 4 5 6 2 11 5 14 54 2 4 5 0 2 19 12 17 39 25 3 138 12 9 4 14 0 0 1 0 0 0 0 0 0 8 0 0 0 2 COG2819(Predicted hydrolase of the alpha/beta superfamily) 117 28 24 20 14 2 14 7 4 1 9 4 2 2 0 0 15 15 6 2 11 20 20 13 17 48 4 6 8 0 6 22 9 2 16 23 7 0 10 11 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG1469(Uncharacterized conserved protein) 115 11 14 8 4 2 1 11 4 1 10 3 6 27 6 4 3 11 12 6 2 8 16 6 3 16 12 0 1 0 2 13 6 12 22 41 4 68 9 22 4 6 0 0 0 0 0 0 0 0 0 5 0 0 0 10 COG1017(Hemoglobin-like flavoprotein) 358 8 10 6 0 1 0 10 4 0 1 1 2 7 6 0 6 13 0 2 0 1 5 0 2 15 0 2 1 0 0 2 3 0 0 5 1 63 4 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG5505(Predicted integral membrane protein) 98 7 43 11 2 1 4 2 11 3 20 4 11 18 8 4 6 2 9 6 7 6 19 9 19 0 15 10 4 0 4 9 15 10 40 34 5 25 10 19 4 3 2 0 0 0 0 0 0 0 0 4 0 0 0 4 NOG20805() 88 77 49 63 4 5 21 4 2 4 1 4 1 3 2 10 0 2 9 2 5 4 25 10 5 5 7 8 18 2 0 15 10 3 34 15 5 8 1 0 4 0 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1896(Predicted hydrolases of HD superfamily) 73 8 9 11 2 1 3 4 1 3 9 1 4 17 6 2 3 5 11 4 5 10 6 7 3 16 18 2 4 1 8 24 19 10 32 22 18 93 9 19 14 11 0 0 0 0 0 0 0 0 0 5 0 0 0 13 COG1069(Ribulose kinase) 120 15 23 18 4 6 7 4 1 2 0 2 4 7 0 0 18 19 5 2 0 1 7 2 5 21 9 5 6 2 2 7 9 5 8 9 6 146 5 12 2 2 0 0 0 0 0 0 0 0 0 8 0 0 0 10 NOG07814() 46 12 9 8 8 2 4 6 11 1 16 12 7 22 11 6 1 12 9 6 6 8 17 12 8 0 8 8 7 5 9 21 18 10 42 46 22 29 9 30 13 6 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG06104() 13 17 32 16 2 2 9 0 6 4 0 7 3 14 12 13 7 11 19 12 7 16 20 4 4 29 9 19 12 5 8 16 16 13 36 53 8 11 21 10 7 7 0 0 0 0 0 0 0 0 0 9 0 0 0 7 NOG09824() 4 9 20 19 1 9 4 21 2 10 5 0 5 11 2 6 5 8 40 6 12 22 32 27 14 5 12 2 8 42 4 29 26 11 2 3 6 65 11 4 1 4 0 0 0 0 0 0 0 0 0 4 0 0 0 12 COG3107(Putative lipoprotein) 88 18 23 5 3 2 6 4 4 3 12 3 2 23 2 2 3 0 12 4 10 3 13 3 2 5 15 2 7 0 2 5 9 8 12 12 25 170 6 5 3 6 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1418(Predicted HD superfamily hydrolase) 53 10 28 8 7 0 8 2 4 3 6 6 2 6 15 7 29 21 10 12 9 2 12 2 9 56 1 7 3 1 1 12 5 4 14 23 56 53 5 18 6 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG4299(Uncharacterized conserved protein) 59 14 55 11 1 6 6 6 9 0 2 11 10 2 14 5 5 4 4 5 3 8 22 7 18 20 6 16 7 1 5 22 9 16 41 27 0 17 11 23 1 8 0 0 0 0 0 0 0 0 0 16 0 0 0 9 COG2421(Predicted acetamidase/formamidase) 40 15 39 14 2 7 2 4 7 7 9 10 2 19 6 6 9 19 10 3 5 16 21 6 3 46 5 6 7 1 7 15 7 0 10 26 0 101 9 9 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG1671(Uncharacterized protein conserved in bacteria) 73 10 9 8 2 2 6 8 2 4 10 4 12 16 2 7 4 4 13 8 4 2 12 10 9 0 9 3 4 3 9 17 11 8 40 15 12 131 12 10 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 6 COG2927(DNA polymerase III, chi subunit) 62 13 31 10 5 5 8 9 4 5 10 1 6 18 6 3 18 10 6 3 6 4 6 6 12 7 15 6 5 3 5 5 15 9 29 14 14 99 12 10 5 2 0 0 0 0 0 0 0 0 0 10 0 0 0 8 COG4301(Uncharacterized conserved protein) 97 40 24 29 3 10 22 8 3 2 3 4 8 11 6 1 3 5 3 1 6 6 17 9 10 2 6 10 7 6 2 16 1 8 8 22 6 91 11 2 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG3818(Predicted acetyltransferase, GNAT superfamily) 11 50 46 38 1 2 6 16 5 1 0 6 0 12 4 8 3 6 8 6 14 11 20 12 8 14 8 5 4 6 9 16 13 8 23 34 1 65 3 17 3 4 0 0 0 0 0 0 0 0 0 6 0 0 0 5 COG3033(Tryptophanase) 17 22 32 18 3 0 18 0 2 0 0 1 5 10 13 7 5 1 4 17 10 9 18 7 10 2 21 28 9 0 8 21 23 15 27 48 8 11 19 14 11 8 2 0 0 0 0 0 0 0 0 7 0 0 0 27 COG2850(Uncharacterized conserved protein) 125 7 5 8 4 4 0 5 4 0 7 8 0 18 10 4 11 10 7 4 3 5 6 2 9 8 2 4 11 7 2 5 6 4 10 4 13 168 0 7 1 4 0 0 0 0 0 0 0 1 0 3 0 0 0 12 COG1507(Uncharacterized conserved protein) 8 2 5 11 0 0 7 5 2 0 2 2 1 12 8 4 19 32 12 2 12 17 13 14 3 75 15 11 6 0 7 5 14 11 15 20 8 126 8 4 4 0 0 0 0 0 0 0 0 0 0 5 0 0 0 9 COG3450(Predicted enzyme of the cupin superfamily) 269 8 18 6 3 1 0 3 5 3 2 0 5 1 2 0 1 5 2 6 6 6 5 12 1 6 3 5 6 10 11 13 5 8 27 8 7 19 14 13 3 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG1641(Uncharacterized conserved protein) 32 17 18 41 3 5 2 2 1 1 0 0 0 6 8 0 6 0 3 9 28 16 34 12 12 28 18 17 16 12 30 12 12 6 7 26 9 52 16 3 5 2 0 0 0 0 0 0 0 0 0 2 0 1 0 3 COG4134(ABC-type uncharacterized transport system, periplasmic component) 86 16 5 12 1 5 9 6 3 9 1 14 4 11 2 5 4 4 12 5 1 2 18 5 4 0 5 8 9 2 5 13 10 14 10 25 0 169 1 3 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 5 NOG14785() 11 13 15 19 0 1 3 2 8 2 0 9 0 3 8 19 2 2 6 4 25 14 33 11 17 0 17 13 18 0 5 23 14 12 25 83 9 1 26 22 9 5 0 0 0 0 0 0 0 0 0 1 0 0 0 23 COG4949(Uncharacterized membrane-anchored protein conserved in bacteria) 80 1 1 2 3 6 5 15 9 0 16 3 4 17 4 2 2 5 8 4 3 3 5 7 16 6 17 4 0 0 7 14 9 7 24 11 6 189 2 7 1 4 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG5632(N-acetylmuramoyl-L-alanine amidase) 147 14 20 9 10 0 6 9 3 2 7 6 3 14 10 4 6 3 7 4 13 6 11 5 9 5 4 2 2 2 6 21 14 15 20 34 3 29 6 19 10 2 0 0 0 0 0 0 0 0 0 4 0 0 0 7 NOG04774() 288 6 14 5 2 0 7 6 3 2 0 0 0 10 0 5 2 8 8 6 4 4 6 3 3 17 0 0 6 1 3 4 8 2 8 25 4 30 0 6 8 2 0 0 0 0 0 0 0 0 0 3 0 2 0 10 COG3001(Fructosamine-3-kinase) 30 18 13 41 6 6 2 2 0 0 2 1 0 3 6 2 0 0 5 2 27 10 23 13 27 0 7 8 21 18 26 12 6 4 9 18 8 107 25 3 4 6 0 0 0 0 0 0 0 1 0 8 0 0 0 1 NOG27975() 1 9 12 16 5 1 5 29 5 9 12 3 17 1 2 1 0 0 11 9 17 28 53 23 26 3 18 15 12 58 4 9 6 10 10 28 0 3 6 7 8 10 0 0 0 0 0 0 0 0 0 14 0 0 0 14 COG5126(Ca2+-binding protein (EF-Hand superfamily)) 3 16 37 39 36 55 2 6 5 4 0 6 2 17 4 10 9 29 31 8 14 9 8 4 5 5 6 0 8 88 5 7 1 0 2 11 6 14 7 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 7 COG2983(Uncharacterized conserved protein) 38 16 4 8 2 6 6 7 5 7 8 11 12 26 9 3 6 1 29 6 8 4 11 6 5 2 9 4 7 2 3 19 13 9 20 26 15 117 8 13 3 7 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG2864(Cytochrome b subunit of formate dehydrogenase) 259 5 4 6 0 0 9 9 1 4 0 0 1 3 4 0 8 2 6 2 8 3 6 10 7 8 4 8 4 0 4 7 5 0 0 5 0 115 6 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4294(UV damage repair endonuclease) 2 5 4 5 2 2 5 33 7 6 4 6 15 17 2 10 16 24 22 12 8 11 21 6 12 84 7 12 10 6 5 29 15 18 15 15 0 15 9 8 4 2 0 0 0 0 0 0 0 0 0 4 0 0 0 14 NOG21394() 8 11 23 6 14 2 12 1 8 5 8 1 4 6 2 1 2 2 5 6 8 6 7 7 3 3 5 13 8 0 7 19 25 22 59 38 0 98 8 26 8 15 0 0 0 2 0 0 0 0 0 8 0 0 0 5 COG1815(Flagellar basal body protein) 99 12 10 16 0 9 8 9 4 1 4 4 9 16 2 2 10 4 8 4 16 3 12 6 10 1 15 9 6 3 7 16 9 9 32 19 7 69 5 15 2 8 0 0 0 0 0 0 0 0 0 6 0 0 0 10 COG1432(Uncharacterized conserved protein) 116 16 21 15 4 4 2 3 5 5 5 4 6 15 3 6 8 6 7 1 2 5 12 0 5 14 6 6 7 1 3 6 5 8 24 19 48 76 5 9 1 8 0 1 0 0 0 0 0 0 0 0 0 0 0 3 COG1690(Uncharacterized conserved protein) 133 14 26 9 3 1 0 0 0 0 1 3 2 2 9 3 7 4 1 5 17 11 21 10 2 38 11 8 3 3 1 8 8 6 1 29 38 47 0 6 7 4 1 2 1 0 0 0 0 0 0 5 0 2 0 13 COG3188(P pilus assembly protein, porin PapC) 469 1 2 0 0 0 0 4 3 2 3 1 4 3 0 0 1 1 1 0 0 0 1 0 0 9 0 0 2 0 2 0 0 0 0 1 1 13 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG22108() 9 8 7 4 2 8 3 12 7 17 10 18 5 32 2 18 20 12 14 7 1 1 4 2 7 0 9 9 3 0 4 13 13 7 36 16 10 125 13 20 3 4 0 0 0 0 0 0 0 0 0 8 0 0 0 3 NOG06254(Peptidase, M50) 15 19 12 14 0 0 5 13 9 9 0 14 6 2 4 0 4 0 3 6 14 5 11 13 7 3 23 21 15 0 4 5 7 10 44 34 20 114 2 8 3 7 0 0 0 0 0 0 0 2 0 9 0 0 0 9 COG3464(Transposase and inactivated derivatives) 30 10 8 1 3 0 0 0 0 4 3 1 0 3 2 3 2 11 2 3 1 0 0 0 4 15 4 2 2 4 3 0 0 0 0 4 48 352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3170(Tfp pilus assembly protein FimV) 88 10 10 10 1 3 2 4 1 2 11 4 4 13 11 5 18 20 14 4 5 1 9 5 4 7 4 5 5 1 3 2 2 2 6 12 28 181 3 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09489() 10 22 49 17 1 5 12 4 1 2 9 3 5 10 6 6 0 1 6 9 7 17 23 8 6 0 6 19 8 0 13 11 8 7 52 65 7 21 16 19 9 7 0 0 0 0 0 0 0 0 0 14 0 0 0 2 NOG11219() 12 15 29 13 8 3 13 14 10 6 6 10 9 9 8 3 4 13 8 8 4 15 12 7 4 8 6 13 3 0 6 23 13 10 61 42 13 15 3 30 14 6 0 0 0 0 0 0 0 0 0 2 0 0 0 12 NOG08141() 114 8 11 14 29 23 5 0 4 0 15 0 5 6 0 3 4 4 10 2 8 5 21 9 7 8 3 6 4 16 0 5 5 6 5 13 0 104 10 5 5 2 0 0 0 0 0 0 0 0 0 7 0 0 0 12 COG1306(Uncharacterized conserved protein) 70 9 14 10 0 0 16 1 0 0 0 0 0 8 15 18 12 5 4 12 7 8 14 5 11 2 17 27 18 0 6 12 10 27 19 64 9 4 11 12 13 9 2 0 0 0 0 0 0 0 0 6 0 0 0 15 NOG26203() 4 10 6 11 15 1 8 23 7 0 4 3 3 6 7 5 3 8 4 11 4 11 16 6 11 9 15 8 10 1 6 22 23 20 73 37 8 20 11 26 16 14 0 0 0 0 0 0 0 0 0 3 0 0 0 12 COG4553(Poly-beta-hydroxyalkanoate depolymerase) 241 4 3 4 1 7 1 0 0 0 4 0 0 13 4 0 13 12 4 1 3 6 3 5 2 12 1 4 2 4 4 9 6 8 14 7 1 94 2 7 3 3 0 0 0 0 0 0 0 0 0 1 0 1 0 7 COG4517(Uncharacterized protein conserved in bacteria) 17 41 50 32 2 3 1 10 2 4 6 4 2 7 3 8 1 0 8 5 2 8 10 6 15 0 13 5 6 3 7 11 16 11 41 27 13 74 12 12 4 9 0 0 0 0 0 0 0 0 0 4 0 1 0 4 COG3643(Glutamate formiminotransferase) 4 14 75 12 0 4 1 0 3 3 8 3 5 3 2 2 5 15 4 17 27 21 27 12 18 21 20 19 15 5 8 13 15 20 11 19 2 5 0 21 11 9 0 0 0 0 0 0 0 0 0 11 0 0 0 10 NOG11858() 24 38 24 51 2 1 10 17 1 1 0 3 3 2 2 5 10 9 2 10 18 18 24 15 12 3 5 15 12 0 13 15 23 9 24 39 11 0 17 7 6 6 0 0 0 0 0 0 0 0 0 9 0 0 0 4 NOG24172() 88 14 19 25 1 1 11 9 1 2 0 6 5 7 8 1 1 4 11 12 4 11 8 7 8 9 16 8 4 2 8 10 6 2 20 47 13 78 4 12 7 0 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG3973(Superfamily I DNA and RNA helicases) 106 7 23 14 0 0 1 0 0 0 0 3 0 0 0 5 15 26 2 3 20 8 23 6 6 75 4 6 1 0 2 4 5 0 7 28 2 95 6 2 0 6 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG4604(ABC-type enterochelin transport system, ATPase component) 71 38 21 18 1 4 9 3 4 0 0 0 1 3 4 4 0 5 4 11 8 15 10 11 12 0 11 15 5 2 15 17 23 6 45 43 6 17 12 2 11 12 0 0 0 0 0 0 0 0 0 4 0 0 0 15 NOG21577(HNH endonuclease) 12 14 11 12 1 0 1 56 3 1 0 0 11 1 1 1 0 4 7 12 6 9 22 18 15 25 5 18 16 33 7 9 5 4 5 3 0 103 24 4 10 2 0 0 0 0 1 0 0 0 0 3 0 0 0 21 COG1923(Uncharacterized host factor I protein) 102 16 14 8 1 2 2 10 1 1 6 2 5 21 6 5 11 7 8 4 6 5 13 4 2 9 4 2 7 0 3 14 7 0 19 23 13 118 4 11 3 1 0 0 0 0 0 0 0 0 4 5 0 0 0 7 COG5274(Cytochrome b involved in lipid metabolism) 32 3 28 4 7 7 1 17 9 5 3 4 5 3 4 3 33 23 8 8 13 10 6 6 3 96 1 7 6 9 1 9 10 1 6 11 10 89 2 5 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG21777() 10 37 53 35 4 4 15 12 9 8 1 4 0 16 2 1 8 4 2 7 7 4 21 6 11 6 1 7 4 10 6 31 15 13 45 34 3 1 14 15 4 13 0 0 0 0 0 0 0 0 0 11 0 0 0 2 COG2032(Cu/Zn superoxide dismutase) 46 10 12 11 7 3 3 26 14 7 4 5 14 21 4 9 18 16 8 12 4 8 6 3 10 14 4 8 5 4 2 16 12 15 21 19 3 72 10 8 3 4 0 0 0 0 0 0 0 0 0 5 0 0 0 9 COG1937(Uncharacterized protein conserved in bacteria) 102 14 14 10 1 3 8 4 4 5 1 4 1 22 5 2 9 19 8 5 5 4 12 5 11 20 13 6 2 1 3 3 5 4 16 5 8 134 5 4 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG0309(Hydrogenase maturation factor) 171 9 11 13 0 3 18 4 1 0 0 0 0 6 2 7 12 7 5 4 4 3 9 1 2 6 0 0 3 0 2 3 0 2 4 4 11 182 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3519(Uncharacterized protein conserved in bacteria) 405 3 3 2 0 2 1 2 0 0 2 0 1 7 0 0 3 0 2 0 6 0 4 2 2 1 1 0 2 0 2 0 0 0 0 0 5 51 0 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 NOG21675() 29 20 16 41 1 1 5 6 4 2 5 3 1 3 2 5 4 3 5 14 11 9 16 20 18 16 9 9 8 2 14 20 19 10 38 48 11 3 15 15 8 2 0 0 0 0 0 1 0 0 0 13 0 0 0 8 COG5501(Predicted secreted protein) 14 25 25 17 0 2 1 12 4 11 6 9 2 16 4 6 18 9 7 7 3 3 19 7 10 12 8 15 6 6 8 8 12 18 21 20 7 109 4 5 3 2 0 0 0 0 0 0 0 0 0 3 0 0 0 8 COG1636(Uncharacterized protein conserved in bacteria) 62 46 40 22 2 1 9 8 0 5 2 5 6 14 11 6 4 1 8 7 13 5 14 10 7 0 4 7 10 7 2 13 13 9 33 55 8 7 9 6 6 5 0 0 0 0 0 0 0 0 0 7 0 0 0 3 COG4097(Predicted ferric reductase) 10 39 51 21 2 4 10 9 5 4 6 0 5 6 2 2 35 10 4 4 14 8 17 11 13 53 4 11 7 6 7 8 8 7 18 25 6 40 10 8 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3332(Uncharacterized conserved protein) 126 21 13 26 4 1 15 9 3 3 10 4 11 18 4 0 10 6 13 9 4 4 14 7 16 10 3 6 5 3 6 9 6 7 17 16 14 42 2 2 1 4 0 0 0 0 0 0 0 0 0 3 0 0 0 5 COG4932(Predicted outer membrane protein) 0 4 20 9 19 5 3 2 2 0 6 22 6 11 6 1 2 10 5 9 14 22 12 11 5 0 14 4 5 4 8 14 42 14 12 39 16 32 11 23 17 20 0 0 0 0 0 0 0 0 0 3 0 0 0 28 NOG24764() 4 7 17 5 5 2 9 6 13 10 0 10 11 2 7 3 3 6 4 8 9 10 15 11 10 16 4 19 7 2 3 23 24 23 70 39 8 6 9 29 19 6 0 0 0 0 0 0 0 0 0 6 0 0 0 12 NOG06029(Major facilitator superfamily protein) 48 6 20 15 1 4 6 8 3 14 8 1 15 29 3 5 0 0 12 5 6 1 9 5 0 0 13 4 3 1 11 19 19 15 40 58 6 51 15 11 0 8 0 0 0 0 0 1 0 0 0 2 0 0 0 9 COG3323(Uncharacterized protein conserved in bacteria) 8 8 9 4 8 1 5 5 5 5 3 1 7 6 5 3 7 24 12 5 3 6 11 3 9 7 9 3 8 1 7 19 11 6 33 20 9 163 4 29 4 4 0 0 0 0 0 0 0 0 0 4 0 0 0 6 NOG34730() 13 59 48 23 3 5 11 2 3 2 6 2 7 13 5 8 0 3 4 7 5 12 19 14 7 0 4 14 7 4 3 28 15 10 49 30 8 16 9 15 2 4 0 0 2 0 0 0 0 0 0 7 0 0 0 2 NOG25508() 2 3 5 8 16 2 9 20 6 14 25 9 3 15 16 16 0 4 21 18 0 14 17 10 11 1 31 16 7 4 6 24 21 13 49 20 6 10 3 18 5 3 0 0 0 0 0 0 0 0 0 0 0 0 0 9 NOG07689() 15 48 52 27 2 4 8 7 5 2 1 5 3 19 11 7 0 0 10 8 9 10 24 7 7 4 7 11 8 3 6 29 10 13 41 33 1 13 8 12 8 1 0 1 0 0 0 0 0 0 0 5 0 0 0 5 COG3833(ABC-type maltose transport systems, permease component) 15 7 8 7 0 1 11 4 0 0 0 0 5 11 7 8 21 16 1 11 8 22 26 11 14 50 19 20 17 1 9 18 21 13 19 20 0 7 9 14 20 10 0 0 0 0 0 0 0 0 0 2 0 0 0 25 NOG11434(Major facilitator protein) 102 28 60 30 0 3 11 6 0 2 2 2 9 1 6 0 3 4 5 5 5 11 22 11 6 4 6 11 8 1 8 6 10 12 24 38 2 0 8 13 6 6 0 0 0 0 0 0 0 0 0 4 1 0 0 5 COG0783(DNA-binding ferritin-like protein (oxidative damage protectant)) 74 15 5 11 8 0 6 1 0 5 2 1 0 2 6 3 10 17 13 2 3 2 5 0 6 120 6 3 3 7 2 15 5 4 10 5 10 109 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3222(Uncharacterized protein conserved in bacteria) 21 16 9 19 4 4 0 0 1 6 4 2 1 28 0 2 3 7 6 6 14 14 28 17 16 0 8 18 12 5 14 24 11 9 29 21 12 66 21 8 3 5 0 0 0 0 0 0 0 0 0 10 0 0 0 2 NOG06242() 17 31 99 26 1 0 0 14 11 2 9 5 12 24 9 9 1 4 30 13 0 4 10 8 3 0 10 5 2 0 0 10 13 16 15 46 7 16 5 11 4 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG1987(Flagellar biosynthesis pathway, component FliQ) 145 10 7 7 2 8 1 6 3 3 8 2 2 7 4 3 2 0 1 4 8 11 16 8 8 6 10 12 7 1 6 14 11 2 24 10 14 69 10 10 2 6 0 0 0 0 0 0 0 0 0 7 0 0 0 7 COG5282(Uncharacterized conserved protein) 0 0 6 4 0 0 0 0 1 0 0 0 1 6 0 0 35 47 5 0 3 7 5 0 2 120 2 4 1 0 0 2 1 2 0 24 0 218 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3138(Arginine/ornithine N-succinyltransferase beta subunit) 220 27 8 9 0 1 1 0 7 0 2 11 0 12 6 3 0 0 3 7 2 10 6 5 5 1 9 6 5 3 3 14 10 8 21 20 10 20 2 7 4 2 0 0 0 0 0 0 0 0 0 4 0 0 0 10 COG2094(3-methyladenine DNA glycosylase) 72 17 11 18 2 4 3 0 0 0 1 1 0 1 10 1 0 2 2 2 25 7 25 21 15 12 6 8 9 11 15 18 5 1 12 9 15 105 17 7 2 0 0 0 0 0 0 0 0 1 0 2 0 0 0 9 NOG23412() 28 33 29 36 2 4 11 10 6 6 0 0 2 12 13 5 4 11 5 11 12 13 16 5 8 1 9 11 8 1 3 16 6 18 20 62 10 6 15 5 2 8 0 0 0 0 0 0 0 0 0 7 0 0 0 14 COG1006(Multisubunit Na+/H+ antiporter, MnhC subunit) 19 9 9 9 3 8 7 7 4 1 5 3 1 8 4 3 0 4 10 7 6 5 8 4 1 0 13 3 2 0 4 11 6 10 36 30 16 198 10 5 2 6 0 0 0 0 0 0 1 0 0 2 0 0 0 4 COG4281(Acyl-CoA-binding protein) 211 3 11 8 0 1 2 0 8 0 0 0 4 5 4 0 6 4 1 3 3 4 10 7 10 29 3 11 3 3 5 3 2 2 6 14 1 101 0 6 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2195(Di- and tripeptidases) 82 2 8 7 5 0 3 14 4 4 7 11 0 6 7 10 8 13 17 10 11 7 14 8 4 24 7 11 9 3 9 15 9 7 21 23 6 59 12 12 4 4 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG36238() 28 20 30 35 0 0 4 13 10 6 5 6 0 0 2 1 3 2 3 9 25 13 27 23 28 1 6 18 17 0 15 10 2 2 34 70 2 0 0 8 2 3 0 0 0 0 0 4 0 0 0 8 0 0 0 8 COG1677(Flagellar hook-basal body protein) 70 13 14 11 1 6 5 3 3 5 3 0 7 11 2 4 6 4 5 9 5 7 17 15 12 11 7 6 7 2 1 11 20 7 20 16 8 109 4 13 3 6 0 0 0 0 2 0 0 0 0 4 0 0 0 8 NOG14504() 19 10 14 23 0 1 2 3 1 1 9 3 7 1 10 9 18 3 2 16 12 12 12 13 6 0 13 4 10 0 16 21 13 16 76 41 10 0 19 12 7 5 0 0 0 0 0 0 0 1 0 8 0 0 0 24 COG4454(Uncharacterized copper-binding protein) 60 43 25 52 0 6 14 7 0 4 0 1 0 8 4 2 7 5 4 12 9 14 26 10 11 10 6 9 9 0 7 8 18 10 24 26 6 6 3 14 0 11 0 0 0 0 0 1 0 0 0 9 0 0 0 2 COG1814(Uncharacterized membrane protein) 6 0 3 3 2 0 1 5 3 3 1 3 2 25 6 5 29 34 16 2 8 4 3 3 2 108 1 0 1 2 0 4 0 0 3 6 20 182 2 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2948(Type IV secretory pathway, VirB10 components) 450 6 4 1 1 0 1 0 0 0 0 0 0 5 0 0 0 1 1 0 0 0 0 0 0 2 3 0 2 0 2 0 0 0 0 0 4 12 0 2 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG0420(DNA repair exonuclease) 169 13 13 16 2 2 0 0 0 0 0 5 6 2 10 1 1 3 2 3 5 3 12 3 4 39 8 1 3 1 6 5 1 0 4 7 21 122 2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4487(Uncharacterized protein conserved in bacteria) 31 12 11 27 7 12 3 9 4 1 2 2 4 0 2 2 5 2 3 4 18 10 38 25 25 7 11 14 21 25 24 17 13 9 13 16 10 13 22 12 2 4 0 0 0 0 0 0 0 0 0 6 1 0 0 1 NOG16480() 10 6 15 2 13 4 4 0 3 2 5 3 2 7 2 1 22 24 6 9 3 9 10 7 9 70 5 6 7 0 5 14 14 28 41 13 0 87 4 13 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG1155(Archaeal/vacuolar-type H+-ATPase subunit A) 0 13 28 14 3 1 0 4 0 0 1 9 2 11 10 1 2 4 4 11 9 19 21 3 5 36 4 10 8 5 5 10 19 2 2 31 43 87 3 8 14 7 0 0 0 0 0 0 0 0 0 3 0 0 0 26 COG1594(DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS) 43 6 26 7 2 2 5 41 22 3 6 13 21 13 11 14 22 25 7 30 7 8 18 5 9 31 4 7 4 4 1 4 10 6 0 13 12 4 5 5 9 3 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG2346(Truncated hemoglobins) 105 5 6 0 1 2 0 1 1 0 0 0 1 5 2 3 35 39 13 0 3 2 4 2 0 63 7 2 1 1 7 0 2 0 2 4 7 162 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG08846() 9 21 33 27 0 1 4 13 3 8 5 1 4 9 5 4 22 5 4 4 7 11 14 4 8 16 14 6 0 0 0 8 5 5 53 31 11 87 5 17 1 5 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG5563(Predicted integral membrane proteins containing uncharacterized repeats) 6 18 27 8 2 0 3 20 23 5 11 3 10 15 2 8 13 12 11 5 11 2 12 1 0 15 0 4 0 0 0 20 13 4 6 28 34 99 5 12 2 16 0 0 0 0 2 0 0 0 0 7 0 0 0 1 NOG19298() 13 10 44 14 0 0 7 3 1 1 0 3 4 25 10 8 3 13 8 9 22 21 29 15 13 27 16 8 16 0 5 12 15 8 8 35 8 17 6 8 7 2 0 0 0 0 0 0 0 0 0 4 0 0 0 18 COG1509(Lysine 2,3-aminomutase) 10 15 23 24 9 2 1 0 6 0 8 8 2 21 21 1 1 5 13 1 7 6 15 9 3 14 3 2 3 2 5 6 1 4 4 17 45 169 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 6 COG3658(Cytochrome b) 105 8 4 6 4 5 2 8 0 1 5 3 1 5 0 0 12 7 5 7 2 4 1 1 4 16 8 4 4 2 4 8 3 2 28 8 10 180 3 8 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG2989(Uncharacterized protein conserved in bacteria) 175 4 7 11 0 2 1 6 8 2 2 2 0 10 4 2 4 4 7 5 0 6 6 11 6 3 7 2 7 0 0 16 7 9 32 17 2 76 10 8 2 6 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG4626(Phage terminase-like protein, large subunit) 30 1 2 1 0 3 1 4 5 0 22 0 4 7 6 1 7 9 23 0 0 0 0 0 0 15 1 2 0 0 0 10 0 2 0 2 2 332 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG5588(Uncharacterized conserved protein) 54 30 23 23 1 5 6 11 1 5 1 1 5 9 0 1 1 6 1 9 4 5 19 13 8 13 7 8 3 1 6 6 7 10 17 42 1 102 6 9 1 8 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG1606(ATP-utilizing enzymes of the PP-loop superfamily) 28 19 22 40 4 6 0 1 1 6 0 0 0 7 6 1 1 2 3 6 20 17 28 27 25 24 6 14 17 12 23 15 7 0 6 19 14 38 19 1 0 0 0 0 2 0 0 0 0 0 0 3 1 0 0 3 COG2087(Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase) 97 9 11 24 1 3 3 4 5 0 3 0 5 16 0 1 2 0 3 0 7 7 27 15 19 3 5 1 12 4 22 21 11 8 34 11 7 35 17 12 3 7 2 0 0 0 0 0 0 0 0 11 0 1 0 5 COG2194(Predicted membrane-associated, metal-dependent hydrolase) 149 14 5 11 5 0 1 8 4 2 15 3 2 37 6 3 33 50 14 5 2 2 4 3 2 44 5 2 3 1 1 6 3 7 12 9 6 0 8 1 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11837() 7 6 8 11 0 1 4 3 5 3 2 4 0 23 14 10 10 19 34 20 15 16 19 8 17 88 16 7 12 0 12 8 12 6 11 36 1 5 3 1 0 4 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG13377() 65 32 49 38 7 1 16 9 4 6 4 6 0 12 1 7 3 0 4 12 12 4 25 8 4 0 5 14 12 2 4 12 13 5 37 11 3 4 6 11 9 4 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG1966(Carbon starvation protein, predicted membrane protein) 205 17 28 7 0 5 0 2 2 1 0 2 0 21 5 8 25 4 5 7 1 11 11 0 6 29 6 2 6 3 0 6 0 0 2 4 16 37 2 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG3411(Ferredoxin) 63 15 40 16 1 0 2 3 0 3 1 4 3 8 8 5 14 4 2 8 18 12 29 16 22 38 6 3 9 12 17 13 5 4 10 7 2 41 16 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG1621(Beta-fructosidases (levanase/invertase)) 86 19 36 13 6 17 12 7 1 3 7 2 7 9 0 2 12 6 10 4 3 9 24 8 10 24 10 6 12 11 3 10 15 3 12 13 9 18 6 11 10 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2976(Uncharacterized protein conserved in bacteria) 70 29 25 16 0 0 2 9 3 3 7 11 5 12 6 10 16 12 11 5 2 8 3 4 4 16 6 4 3 0 2 4 2 2 14 27 18 104 6 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG1877(Trehalose-6-phosphatase) 85 6 8 9 13 4 18 5 1 1 2 1 0 4 0 4 0 35 6 1 8 6 4 6 0 3 2 10 1 2 2 5 1 0 6 3 5 209 0 7 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG4586(ABC-type uncharacterized transport system, ATPase component) 72 6 7 14 4 4 0 4 0 5 0 0 0 8 3 7 9 2 2 7 25 8 34 11 26 36 3 8 14 22 13 12 8 5 15 9 11 23 27 5 6 2 0 0 0 0 0 0 1 0 0 4 0 1 0 6 NOG06228(Alpha-Glucosidase) 81 27 56 4 6 0 10 6 2 4 6 3 2 0 2 1 2 2 3 13 13 15 18 7 6 4 25 3 12 1 2 4 4 14 22 33 8 8 4 13 10 2 0 0 0 0 0 0 0 0 0 2 0 0 0 29 COG3626(Uncharacterized enzyme of phosphonate metabolism) 39 46 13 24 3 21 39 0 0 0 0 0 0 2 0 1 0 1 2 1 12 2 20 5 8 12 0 0 0 0 6 0 0 0 0 0 0 231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2862(Predicted membrane protein) 93 13 13 16 3 2 5 3 1 1 1 0 2 6 0 2 27 30 1 1 7 3 6 6 1 61 7 8 6 1 5 10 14 0 20 10 13 47 15 13 3 2 0 0 0 0 0 0 0 0 0 7 0 0 0 3 COG4577(Carbon dioxide concentrating mechanism/carboxysome shell protein) 45 5 1 20 1 0 2 0 0 0 0 0 0 0 0 0 0 0 4 3 15 7 13 9 7 6 3 3 6 9 8 14 0 2 2 2 10 263 14 5 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG07813() 10 44 31 27 0 1 7 10 1 2 0 14 9 22 15 13 4 4 7 3 12 5 23 6 12 0 13 2 6 7 8 23 8 16 37 39 3 0 12 14 2 6 0 1 0 0 0 0 0 0 0 8 0 0 0 0 NOG04790() 4 7 17 13 10 2 22 6 15 2 4 9 4 13 8 3 2 4 14 11 4 7 12 15 6 2 7 12 4 2 5 21 21 13 57 37 13 23 7 21 10 8 0 0 0 0 0 0 0 0 0 4 0 0 0 4 NOG06392() 7 9 7 1 8 1 6 19 6 6 18 6 0 16 8 2 4 4 5 4 7 5 12 4 8 7 6 8 10 2 0 29 20 26 72 31 11 31 9 23 6 6 0 0 0 0 0 0 0 0 0 10 0 0 0 5 COG3872(Predicted metal-dependent enzyme) 10 17 46 15 0 0 9 4 4 0 0 6 0 4 8 8 8 5 5 9 14 10 24 13 9 12 17 14 17 2 5 13 12 15 4 50 12 38 5 6 10 3 0 0 0 0 0 0 0 0 0 6 0 0 0 16 COG1438(Arginine repressor) 48 10 6 4 0 0 9 4 0 0 0 3 1 1 3 12 20 32 8 9 9 8 21 6 10 79 10 23 12 0 5 5 11 1 17 21 4 37 7 2 6 1 0 0 0 0 0 0 0 0 0 2 0 0 0 17 COG4579(Isocitrate dehydrogenase kinase/phosphatase) 107 16 18 8 3 0 2 11 3 2 4 0 6 12 8 10 5 8 7 0 1 9 5 5 5 10 9 4 2 7 1 7 10 4 8 28 5 123 3 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4392(Predicted membrane protein) 97 15 18 13 1 1 5 0 0 3 1 3 1 8 0 9 18 23 9 13 14 3 10 4 7 22 11 2 5 0 3 12 12 9 39 24 8 36 5 5 5 2 0 0 0 0 0 0 0 0 0 0 0 0 1 5 COG3613(Nucleoside 2-deoxyribosyltransferase) 86 7 31 8 0 0 9 4 3 2 1 6 0 10 12 15 4 8 6 14 7 6 28 10 3 17 16 18 7 0 6 17 20 6 25 17 2 6 12 6 9 2 0 0 0 0 0 0 1 0 0 4 0 0 0 11 COG1543(Uncharacterized conserved protein) 31 10 2 23 2 7 3 1 0 0 0 0 0 0 0 0 2 2 0 6 22 11 30 28 43 6 6 9 13 29 9 18 1 0 4 2 4 103 37 6 1 0 0 0 0 0 0 0 0 0 0 8 0 0 2 1 COG2005(N-terminal domain of molybdenum-binding protein) 236 3 8 7 1 3 4 2 0 1 0 1 1 20 2 0 5 4 7 0 7 5 2 4 5 6 1 2 2 0 2 5 2 2 6 6 13 97 1 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG35619() 0 1 1 2 0 4 1 42 7 18 26 8 13 24 10 5 13 12 16 11 6 5 12 3 4 93 8 2 3 7 3 19 12 6 14 9 2 31 3 2 4 4 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG3142(Uncharacterized protein involved in copper resistance) 73 10 31 7 0 1 6 6 4 5 6 5 2 6 8 2 0 3 8 7 9 11 14 7 8 4 12 10 5 4 4 11 19 18 32 47 5 9 14 18 12 0 0 0 0 0 0 0 0 0 0 11 0 0 0 5 COG5048(FOG: Zn-finger) 1 58 31 101 24 21 0 7 0 3 0 0 0 12 4 6 2 4 37 1 7 10 8 0 1 10 1 0 0 21 0 0 1 4 4 6 91 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19662(Transposase) 5 3 4 2 2 0 0 5 0 0 0 0 0 0 0 3 1 2 10 0 2 1 2 0 2 2 1 0 0 0 4 1 0 0 6 2 26 392 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1179(Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1) 83 10 14 5 1 2 2 6 0 4 0 6 1 4 8 9 21 10 4 4 2 7 6 1 0 37 5 6 3 2 4 4 8 4 4 7 18 154 0 3 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG3555(Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases) 116 4 10 11 2 10 6 21 16 0 2 7 14 7 8 7 10 15 7 8 7 7 9 5 7 20 5 2 4 10 3 12 4 1 24 6 4 39 7 1 4 6 0 0 0 0 0 0 0 0 0 3 0 0 0 8 NOG11067() 44 56 29 24 4 0 8 14 4 8 4 4 3 13 5 10 4 0 6 11 10 7 17 4 7 0 5 8 6 2 8 16 19 7 50 30 0 4 5 3 6 2 0 0 0 0 0 0 0 0 0 4 0 0 1 7 COG2370(Hydrogenase/urease accessory protein) 59 19 31 21 7 6 1 9 8 1 0 2 0 4 3 5 0 0 2 3 1 1 6 4 9 1 5 9 2 2 4 12 9 11 26 33 12 125 2 10 0 4 0 0 0 0 0 0 0 0 0 3 0 0 0 5 COG3707(Response regulator with putative antiterminator output domain) 131 14 4 0 0 3 1 0 2 0 1 0 2 5 3 0 23 21 3 0 2 0 0 0 1 77 1 1 2 1 0 1 1 0 0 16 5 153 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG0792(Predicted endonuclease distantly related to archaeal Holliday junction resolvase) 72 8 4 3 10 2 2 7 3 5 13 2 3 22 3 2 27 28 14 5 4 3 3 8 4 66 7 2 1 3 2 6 5 4 4 1 26 80 4 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG23746() 0 2 3 3 1 1 3 41 6 10 41 3 8 5 4 8 8 22 18 5 3 1 19 9 11 58 7 6 13 26 6 21 19 6 6 3 6 35 3 5 2 8 0 0 0 0 0 0 0 0 0 0 0 0 0 11 COG3942(Surface antigen) 23 22 20 22 6 3 10 16 10 4 14 9 10 19 5 4 10 12 9 6 6 3 14 8 12 7 8 9 4 4 10 7 11 8 25 32 10 13 6 15 9 8 0 0 0 0 0 0 0 0 0 3 0 0 0 10 NOG06415() 3 3 15 4 10 4 16 14 11 4 6 8 7 10 8 5 4 4 13 3 8 15 10 0 3 8 19 9 7 1 8 10 19 14 44 53 4 16 11 36 11 10 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG0434(Predicted TIM-barrel enzyme) 25 19 20 12 1 1 6 3 4 1 2 2 0 2 10 4 4 3 7 27 9 15 25 13 6 11 10 19 8 0 10 16 13 7 22 38 7 25 21 13 6 6 0 0 0 0 0 0 0 0 0 3 0 0 0 19 NOG08355(Protein involved in pathogenesis) 14 8 12 15 5 10 2 26 5 2 4 2 17 27 11 1 9 4 22 8 1 11 12 10 5 16 11 11 1 10 7 16 12 1 11 28 10 64 9 13 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG4946(Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system) 177 7 20 7 1 3 2 0 0 2 4 2 2 8 6 0 1 0 0 5 12 7 15 5 7 11 9 10 2 8 5 8 9 2 4 9 1 73 6 11 1 6 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG3823(Glutamine cyclotransferase) 2 12 24 11 10 2 7 3 11 3 8 3 7 15 4 8 3 5 3 17 11 15 30 10 8 11 8 9 9 6 9 18 11 8 33 36 6 16 12 17 13 9 0 0 0 2 0 0 0 0 0 3 0 0 0 6 COG4135(ABC-type uncharacterized transport system, permease component) 21 12 3 9 2 6 6 16 5 10 10 3 1 11 2 4 3 2 5 3 3 1 18 5 9 8 11 2 0 1 11 19 15 14 21 25 0 147 3 6 4 6 0 0 0 0 0 0 0 0 0 5 0 0 0 5 COG5621(Predicted secreted hydrolase) 74 24 15 13 4 3 2 1 2 3 3 2 2 9 2 2 7 4 6 4 4 5 12 7 4 29 17 6 7 3 0 18 7 6 12 16 3 86 12 8 9 6 0 0 0 0 0 0 0 0 0 3 0 0 0 11 COG3579(Aminopeptidase C) 19 29 46 23 5 3 7 4 0 0 4 1 0 0 15 3 13 0 1 20 14 14 24 14 16 1 7 6 21 4 8 15 12 5 19 36 13 10 5 12 6 4 0 0 0 0 0 0 0 0 0 3 0 0 0 10 COG4934(Predicted protease) 331 1 2 5 4 8 0 4 0 0 0 0 0 0 0 0 4 2 4 0 1 0 1 0 2 2 1 0 1 22 0 2 0 0 0 2 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4270(Predicted membrane protein) 10 21 48 18 1 1 8 3 3 1 6 5 7 16 12 6 1 3 0 11 7 16 22 7 7 33 5 6 6 1 6 6 23 10 26 50 0 4 5 15 9 8 0 0 0 0 0 0 0 0 0 4 0 0 0 14 NOG36157() 18 17 12 26 1 2 11 15 3 3 2 10 7 9 5 13 9 6 11 13 8 10 14 9 5 0 18 13 6 0 4 17 14 16 40 24 21 0 18 8 7 4 0 0 0 0 0 0 2 0 0 8 0 0 0 12 NOG15757() 17 27 20 19 4 4 3 23 7 5 0 14 4 18 6 12 6 5 9 4 5 6 14 6 7 76 5 9 6 2 0 11 8 15 22 19 4 6 28 5 2 4 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG08730() 199 22 65 14 2 0 0 12 2 2 8 0 9 9 4 0 2 0 4 3 6 2 4 3 1 0 2 5 1 1 0 13 15 2 18 15 2 1 3 13 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4365(Uncharacterized protein conserved in bacteria) 1 10 16 15 8 0 11 4 13 1 12 4 0 10 4 0 3 3 3 7 6 7 14 3 10 12 14 9 3 1 2 20 22 13 59 37 1 35 11 33 8 6 0 0 0 0 0 0 0 0 0 8 0 0 0 11 COG4403(Lantibiotic modifying enzyme) 13 16 10 13 0 1 4 10 2 7 2 0 2 5 0 0 6 6 6 5 17 11 10 12 6 10 21 10 10 7 9 17 14 19 35 46 21 48 10 9 4 3 0 0 0 0 0 0 0 0 0 2 0 0 0 11 COG1501(Alpha-glucosidases, family 31 of glycosyl hydrolases) 113 17 26 12 7 16 1 9 1 1 4 1 4 23 2 0 6 9 7 3 7 5 6 1 5 14 9 7 2 13 0 12 3 8 19 5 14 68 1 5 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3345(Alpha-galactosidase) 14 7 1 0 1 2 0 7 4 8 13 10 13 33 8 9 28 62 9 5 1 3 3 0 2 158 2 0 1 3 0 2 5 8 2 1 3 32 2 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3523(Uncharacterized protein conserved in bacteria) 333 3 3 0 1 1 2 0 0 0 2 3 0 2 0 0 8 5 0 2 0 1 1 0 0 0 2 2 3 0 0 2 0 2 6 0 4 77 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG5486(Predicted metal-binding integral membrane protein) 124 22 20 16 0 3 4 8 1 3 0 5 2 13 2 0 2 5 2 7 4 5 19 12 7 16 6 4 5 2 4 9 8 14 20 34 7 9 4 14 1 8 0 0 0 0 0 0 0 0 0 9 0 0 0 8 COG1245(Predicted ATPase, RNase L inhibitor (RLI) homolog) 76 19 23 15 1 2 0 2 0 0 6 1 2 11 10 0 0 6 3 22 11 22 24 14 11 12 18 17 4 6 10 6 7 4 2 13 26 8 7 14 5 7 2 0 0 0 0 0 0 0 0 2 0 0 0 16 NOG25259() 1 7 33 8 1 0 7 13 6 7 2 6 12 2 5 4 8 5 8 10 2 5 2 8 4 26 4 11 7 3 3 24 18 16 87 25 4 12 7 32 5 4 0 0 0 0 0 0 0 0 0 4 0 0 0 9 NOG36758() 10 6 5 5 1 10 0 8 3 0 5 3 8 27 0 4 6 5 26 8 7 7 4 3 0 19 2 3 4 2 2 6 5 0 16 7 0 218 2 10 1 2 0 0 0 0 0 0 0 0 0 6 0 0 0 1 COG4943(Predicted signal transduction protein containing sensor and EAL domains) 393 6 1 0 0 0 0 0 0 0 0 1 0 7 0 1 0 1 2 0 0 0 1 0 0 4 5 0 0 0 0 0 0 0 2 0 7 33 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07967() 5 11 10 12 18 2 15 4 9 2 1 3 6 9 2 3 6 12 7 1 1 9 8 5 14 1 9 10 6 2 4 5 19 13 49 69 13 45 6 14 10 5 0 0 0 0 0 0 0 0 1 3 0 0 0 7 COG3262(Ni,Fe-hydrogenase III component G) 25 9 26 9 3 4 6 0 0 2 5 0 0 5 0 1 6 6 0 3 4 13 13 7 10 42 12 10 9 1 11 19 4 9 16 47 4 84 19 2 7 1 0 0 0 0 0 0 0 0 0 3 0 0 0 9 COG4104(Uncharacterized conserved protein) 322 3 4 2 0 0 3 25 7 3 7 5 1 3 2 3 6 3 4 1 1 4 3 6 3 5 3 2 4 3 2 5 4 1 0 2 0 5 2 0 1 2 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG1389(DNA topoisomerase VI, subunit B) 4 11 35 16 0 0 0 1 0 0 0 0 0 7 11 3 4 0 2 2 15 26 20 19 4 33 10 8 6 2 1 16 17 13 0 37 24 36 9 13 17 14 0 0 0 0 2 0 0 0 0 5 0 0 0 23 NOG27146() 16 6 19 4 1 0 11 5 3 0 2 8 2 13 8 12 10 0 3 15 11 7 23 9 12 0 21 22 13 2 6 10 21 25 20 49 4 16 10 8 9 4 0 0 0 0 0 0 0 0 0 1 0 0 0 25 COG2372(Uncharacterized protein, homolog of Cu resistance protein CopC) 255 14 17 9 0 1 0 0 0 0 0 1 0 8 2 0 12 16 2 0 2 2 0 0 1 46 0 0 0 0 0 0 1 0 0 3 0 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG37683() 17 10 22 28 4 10 1 10 1 9 17 4 10 5 2 0 5 16 5 9 13 14 26 10 21 43 8 8 12 17 12 14 10 2 16 8 0 7 17 5 2 4 0 0 1 1 0 0 0 0 0 6 0 0 0 3 COG3764(Sortase (surface protein transpeptidase)) 48 9 11 11 0 0 11 4 1 2 1 2 4 19 14 5 2 8 3 15 12 9 19 7 15 16 13 17 7 0 3 13 7 9 8 54 7 11 15 11 15 0 0 2 0 0 0 0 0 0 0 4 0 0 1 20 COG0753(Catalase) 408 22 4 0 0 1 1 0 0 0 0 0 0 0 2 0 0 1 1 0 0 2 3 0 0 3 1 0 3 0 0 2 0 0 2 1 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4930(Predicted ATP-dependent Lon-type protease) 17 13 14 15 1 1 5 11 1 6 3 5 6 18 14 4 6 2 8 14 12 9 9 16 14 13 12 9 4 0 12 11 15 8 37 17 7 50 13 12 3 0 0 0 0 0 0 0 0 0 0 13 0 0 0 4 NOG16062() 14 12 15 7 20 6 17 14 6 6 11 7 0 17 8 12 11 1 25 18 6 0 11 2 3 4 9 3 12 6 8 13 22 21 40 14 11 2 6 12 5 13 0 0 0 0 0 0 0 0 0 9 1 0 0 4 NOG10619() 10 25 12 21 2 3 10 8 3 9 1 6 5 10 2 5 0 12 6 6 16 5 29 9 6 26 10 7 6 6 6 21 20 12 32 28 2 26 6 15 5 12 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG19564() 11 34 18 11 1 2 9 9 5 6 0 2 6 12 2 10 4 3 13 11 3 3 13 2 7 2 12 16 10 4 2 21 19 15 56 36 9 13 7 21 12 1 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1661(Predicted DNA-binding protein with PD1-like DNA-binding motif) 63 13 23 19 2 4 6 0 0 0 0 0 0 3 2 1 0 2 2 11 25 11 29 13 20 2 6 4 20 18 15 19 10 2 0 23 4 29 22 9 15 4 1 0 0 0 0 0 0 0 0 3 0 0 0 8 COG4421(Capsular polysaccharide biosynthesis protein) 14 26 20 32 1 0 3 5 1 3 3 2 2 2 4 3 3 6 7 4 17 5 15 9 15 40 7 9 8 0 6 12 13 8 19 40 4 48 19 9 7 2 0 0 0 0 0 0 0 0 0 3 0 0 0 7 COG1878(Predicted metal-dependent hydrolase) 53 17 21 17 1 3 5 2 3 4 2 3 0 14 6 6 9 13 15 5 5 17 10 7 12 28 5 10 8 2 9 8 6 7 23 28 10 42 4 8 2 1 0 0 0 0 0 0 0 0 0 6 0 0 0 6 COG2894(Septum formation inhibitor-activating ATPase) 84 10 6 12 1 3 2 0 0 0 1 1 0 0 0 0 3 1 2 0 18 2 35 16 14 1 6 9 12 12 19 21 5 4 2 2 3 131 13 2 2 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 NOG10018() 10 9 9 13 9 1 4 8 2 0 1 5 5 6 10 3 8 10 11 1 5 6 14 9 21 66 9 17 16 4 19 10 13 4 22 30 11 15 4 7 3 9 0 0 0 0 0 0 0 0 0 10 0 0 0 13 NOG04673(Transposase) 294 50 12 3 1 0 0 2 0 0 0 2 0 0 0 0 0 1 0 1 0 0 1 1 0 0 2 0 0 5 0 0 0 0 0 0 0 83 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3199(Uncharacterized conserved protein) 106 11 20 8 1 1 2 2 2 2 3 4 0 15 3 2 6 0 14 17 8 18 31 7 8 3 5 1 9 2 1 7 8 12 0 47 10 9 9 12 5 6 0 0 0 0 0 0 0 0 0 1 4 0 0 19 COG1419(Flagellar GTP-binding protein) 162 19 16 6 3 3 2 2 4 0 3 1 3 4 2 1 6 8 3 3 1 5 11 2 13 4 8 4 3 1 5 4 2 0 2 3 6 129 2 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG05989() 228 16 7 16 0 1 6 8 5 3 0 3 4 5 4 1 3 0 0 5 4 5 15 7 6 0 9 5 9 0 4 4 6 6 11 20 2 6 0 2 1 12 0 0 0 0 0 0 0 0 0 9 0 0 0 2 COG0003(Oxyanion-translocating ATPase) 18 2 6 1 1 1 0 9 0 0 0 0 0 18 5 9 10 29 9 4 8 8 11 4 2 63 5 2 1 8 0 8 8 11 0 2 7 160 7 6 6 0 0 0 0 0 0 0 0 0 0 0 0 1 0 10 COG5049(5-3 exonuclease) 4 9 12 15 9 7 9 17 5 4 17 6 12 19 10 13 35 44 14 7 3 8 16 8 16 27 14 5 6 7 5 5 7 12 8 24 4 6 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG04758(Photosystem II 44 kDa protein) 39 7 10 25 8 8 2 0 0 3 0 0 0 2 0 4 0 0 1 7 25 21 39 23 30 2 0 5 16 13 17 34 7 2 9 1 0 66 20 3 2 2 0 0 0 0 0 0 0 0 0 3 0 2 0 1 COG4099(Predicted peptidase) 7 15 41 12 2 5 5 9 4 7 2 7 0 20 10 6 6 4 7 9 12 12 10 13 6 3 12 12 2 4 6 9 12 7 60 34 4 21 6 16 7 2 0 0 0 0 0 0 0 0 0 3 0 0 0 7 NOG10128(Transcriptional regulator protein) 5 5 2 7 2 3 1 7 0 7 5 0 4 26 10 6 4 6 5 6 4 0 11 7 11 12 7 4 10 2 3 24 23 14 34 23 2 114 13 19 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG5281(Phage-related minor tail protein) 39 2 3 0 2 0 1 23 2 7 4 6 7 7 4 2 4 9 14 1 2 1 4 3 0 4 4 4 4 1 3 3 7 0 4 5 2 261 3 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4964(Flp pilus assembly protein, secretin CpaC) 133 14 1 12 3 1 4 0 0 0 0 4 0 3 0 1 5 8 0 4 4 3 5 4 8 11 6 2 1 1 4 2 3 0 4 4 50 145 4 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG4801(Predicted acyltransferase) 104 6 11 9 1 9 5 25 5 6 0 4 4 5 12 21 17 3 6 2 3 3 4 5 2 0 3 6 6 1 10 8 10 9 32 41 15 8 8 11 11 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG4085(Predicted RNA-binding protein, contains TRAM domain) 320 1 6 7 8 1 1 6 2 3 0 0 2 2 0 1 2 8 3 4 0 2 2 1 2 0 3 3 0 5 0 9 6 2 14 4 0 6 4 10 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 3 COG2257(Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB) 143 11 14 7 3 8 2 1 3 4 5 2 4 11 6 3 8 16 5 1 9 3 10 4 13 14 7 4 5 0 1 9 4 4 18 3 16 63 3 2 0 2 0 0 1 0 0 0 0 0 0 1 0 0 0 2 COG5479(Uncharacterized protein potentially involved in peptidoglycan biosynthesis) 0 11 34 7 4 2 2 12 2 0 5 0 1 10 2 3 5 4 7 6 7 7 6 4 5 5 4 2 3 1 2 4 18 6 6 26 8 198 6 4 0 8 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG4564(Signal transduction histidine kinase) 326 3 3 0 0 0 0 0 0 0 0 0 0 0 2 0 5 7 1 0 0 0 2 2 0 13 1 1 2 0 1 2 0 0 2 4 27 50 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1482(Phosphomannose isomerase) 20 1 3 7 1 2 2 3 1 0 2 4 2 10 4 3 13 23 18 5 3 3 2 0 8 63 4 2 5 1 2 3 1 3 3 8 2 210 2 1 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1516(Flagellin-specific chaperone FliS) 86 12 10 7 2 9 8 3 1 5 6 0 1 8 0 1 6 5 4 7 6 5 12 9 0 10 13 2 7 0 6 2 6 3 12 19 8 128 5 9 2 6 0 0 0 0 0 0 0 0 0 0 1 0 0 3 COG1312(D-mannonate dehydratase) 10 18 30 14 9 5 12 1 2 2 8 2 0 17 12 1 8 5 12 6 7 11 32 13 6 7 5 3 6 0 10 12 10 16 24 32 7 24 8 19 6 6 0 1 0 0 0 0 0 0 0 6 0 0 0 9 COG2975(Uncharacterized protein conserved in bacteria) 41 34 37 20 1 0 11 13 5 9 6 1 4 13 2 5 4 3 12 14 6 8 15 5 8 3 2 6 8 1 1 17 13 14 37 38 7 0 9 6 2 6 0 0 0 0 0 0 0 0 0 4 0 0 0 3 COG3760(Uncharacterized conserved protein) 24 21 21 36 1 5 12 22 3 3 3 5 2 8 2 1 1 0 2 11 5 12 20 8 14 0 10 13 7 3 8 25 13 6 33 26 5 26 6 7 7 5 0 0 0 0 0 0 0 0 0 8 0 0 0 3 COG1881(Phospholipid-binding protein) 215 23 23 15 3 2 4 1 1 0 0 0 0 3 2 1 13 12 3 1 2 2 4 4 4 53 3 0 2 1 0 2 0 5 1 2 16 27 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1970(Large-conductance mechanosensitive channel) 101 3 9 5 1 0 7 4 3 4 5 5 1 6 7 8 11 10 12 10 8 11 7 6 6 16 15 15 4 0 3 21 8 4 12 25 7 33 11 10 4 2 0 0 0 0 0 0 0 0 0 3 0 0 0 10 COG3241(Azurin) 46 26 56 16 4 10 2 7 4 3 3 1 0 7 10 0 2 1 11 4 7 10 4 6 6 15 5 5 3 3 1 17 7 12 25 33 2 36 8 13 5 8 0 0 0 0 0 0 0 1 0 4 0 0 0 3 COG0813(Purine-nucleoside phosphorylase) 69 9 9 3 0 2 2 5 7 4 0 8 0 7 16 11 15 18 10 12 3 5 7 0 1 63 6 1 2 1 4 19 12 2 21 26 2 10 11 20 10 8 0 0 0 0 0 0 0 0 0 5 0 0 0 6 NOG39103() 15 12 26 27 0 0 0 5 5 3 0 0 2 1 2 5 16 9 6 9 9 6 14 4 2 15 12 7 1 1 5 15 21 15 41 86 3 2 16 16 3 7 0 0 0 0 0 0 0 0 0 5 0 0 0 3 COG3627(Uncharacterized enzyme of phosphonate metabolism) 40 28 10 26 4 19 38 0 0 0 0 0 0 8 0 2 0 0 3 5 11 6 18 8 8 16 0 0 0 0 2 0 0 0 0 0 0 199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4094(Predicted membrane protein) 96 11 7 14 2 7 3 3 0 3 0 0 1 11 4 0 6 2 7 2 13 1 26 11 19 4 7 5 13 17 27 13 4 4 2 7 9 43 30 0 0 2 0 0 0 0 0 0 0 0 0 9 0 0 0 7 COG2343(Uncharacterized protein conserved in bacteria) 94 7 18 14 3 2 1 4 1 0 4 1 3 10 7 0 6 1 6 5 5 4 6 3 2 2 5 0 6 2 2 14 4 0 6 4 8 174 11 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2322(Predicted membrane protein) 5 8 46 12 11 6 10 5 7 3 4 11 0 6 8 1 4 5 6 9 7 12 16 12 6 10 8 10 4 1 5 13 12 16 29 22 2 36 8 31 5 3 0 0 0 0 0 0 0 0 0 8 0 1 0 6 NOG07796() 223 14 10 11 2 4 15 7 7 6 0 0 7 4 4 0 1 0 0 0 5 13 22 5 13 8 8 4 10 0 4 9 8 3 2 6 2 0 1 4 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG1695(Predicted transcriptional regulators) 131 7 13 11 2 1 5 6 4 5 3 3 0 5 0 1 25 20 7 0 5 0 3 1 3 51 6 4 1 2 2 4 2 0 15 9 12 62 4 7 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 2 COG2938(Uncharacterized conserved protein) 78 15 19 15 3 3 4 8 6 2 6 2 8 8 4 1 3 0 5 6 2 3 12 6 11 0 7 1 4 0 3 11 4 9 16 31 5 108 6 3 1 7 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG2085(Predicted dinucleotide-binding enzymes) 78 22 34 15 2 1 1 3 1 2 0 0 4 20 4 6 8 4 4 3 10 4 3 6 6 33 3 7 3 2 5 16 2 9 13 27 5 59 2 16 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG04724() 36 5 4 32 10 7 4 0 0 0 0 0 0 0 0 0 0 0 0 2 46 4 42 24 25 0 5 3 30 27 28 18 2 4 6 2 0 49 22 3 0 2 0 0 0 0 0 0 1 0 2 4 0 0 0 0 COG1156(Archaeal/vacuolar-type H+-ATPase subunit B) 2 8 33 18 4 4 0 4 0 0 0 4 0 7 11 1 0 1 1 11 9 20 16 2 13 21 10 10 5 7 5 16 15 8 8 15 17 82 7 9 11 19 0 0 0 0 0 0 0 0 0 0 0 0 0 14 COG3695(Predicted methylated DNA-protein cysteine methyltransferase) 50 8 14 13 8 2 4 2 10 0 7 3 2 7 5 2 3 6 10 5 5 8 9 3 6 9 10 9 8 5 2 17 11 6 35 36 4 44 22 13 4 4 0 0 0 0 0 0 0 0 2 6 0 0 2 6 COG1251(NAD(P)H-nitrite reductase) 222 23 2 2 1 0 2 4 0 2 8 2 0 19 4 3 7 10 15 0 0 2 0 0 2 4 5 0 4 3 4 0 0 2 2 2 27 57 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4867(Uncharacterized protein with a von Willebrand factor type A (vWA) domain) 1 2 10 4 7 3 11 5 7 1 7 3 8 10 2 10 7 7 4 6 4 8 18 4 4 31 3 4 6 0 6 12 22 9 35 20 8 91 4 26 6 7 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG06554(Chlorophyllide reductase 52.5 kDa chain) 7 5 5 10 0 2 2 5 5 4 3 0 5 16 2 2 6 2 10 3 6 4 8 12 10 15 6 6 6 0 0 22 23 16 39 19 2 112 3 20 9 4 0 0 0 0 0 0 0 0 0 5 0 0 0 6 COG1310(Predicted metal-dependent protease of the PAD1/JAB1 superfamily) 22 11 28 20 2 7 2 10 0 13 4 1 6 2 8 4 8 19 10 13 5 3 9 5 6 44 10 4 2 12 8 6 11 1 8 24 1 87 1 1 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG1811(Uncharacterized membrane protein, possible Na+ channel or pump) 8 12 15 5 1 0 6 0 1 2 0 5 3 6 2 7 35 34 5 5 8 11 12 11 9 50 11 12 5 0 3 9 14 9 21 34 1 16 11 4 10 6 0 0 0 0 0 0 0 0 0 10 0 0 0 15 COG3267(Type II secretory pathway, component ExeA (predicted ATPase)) 142 29 20 7 0 0 1 4 1 9 10 3 2 16 8 4 0 5 8 9 0 4 4 4 8 4 9 0 3 0 1 6 5 8 6 16 20 59 3 3 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 NOG07781(Glycosyl transferase, group 1) 324 4 10 7 1 2 1 2 0 0 0 0 2 0 4 1 1 6 1 2 2 2 0 0 2 5 2 0 0 0 0 5 2 0 7 14 10 20 0 3 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG06278(Nucleoside protein) 16 15 47 16 1 2 13 9 0 5 8 7 3 8 5 7 4 1 10 11 8 7 18 6 2 19 4 23 6 3 2 9 13 7 19 26 4 44 6 16 4 5 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG3536(Uncharacterized protein conserved in bacteria) 103 17 11 9 7 6 1 3 6 5 4 3 4 10 4 7 15 9 13 2 6 5 6 10 7 11 9 4 4 5 3 11 13 2 12 17 22 37 4 6 4 2 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG19773() 10 22 37 18 2 3 8 4 3 6 0 4 1 13 3 5 6 9 7 6 8 3 27 12 9 44 14 6 10 2 2 12 17 10 20 28 3 15 15 5 2 3 0 0 0 0 0 0 0 0 0 3 0 0 0 7 NOG24756() 2 8 36 13 14 0 9 4 2 4 2 5 2 4 6 4 2 5 4 6 4 8 17 6 18 5 6 8 8 0 8 16 15 6 64 21 2 51 20 8 8 2 0 0 0 0 0 0 0 0 0 4 0 0 0 6 COG3724(Succinylarginine dihydrolase) 155 18 17 8 1 2 0 0 1 0 2 4 0 21 9 4 0 0 5 6 2 11 5 5 4 2 4 9 5 3 2 16 11 4 31 15 4 25 4 6 4 2 0 0 1 0 0 0 0 0 0 4 0 0 0 11 COG3621(Patatin) 14 35 27 16 0 2 6 11 7 7 5 4 1 19 6 7 2 0 9 13 11 15 7 6 6 7 5 10 12 4 8 27 14 4 27 31 2 19 10 13 4 3 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG2344(AT-rich DNA-binding protein) 16 8 18 6 0 0 11 1 7 0 0 2 0 16 3 8 8 5 7 9 6 3 18 13 13 34 9 7 9 0 2 10 15 11 16 26 7 75 4 7 8 4 0 0 0 0 0 0 0 0 0 3 0 0 0 17 COG2891(Cell shape-determining protein) 75 17 30 11 2 1 2 8 0 2 4 5 2 8 2 3 18 10 5 6 2 1 10 1 10 12 3 3 3 0 2 4 8 4 12 26 11 103 2 5 3 4 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4137(ABC-type uncharacterized transport system, permease component) 70 4 10 6 1 1 0 12 2 4 7 4 6 14 8 5 7 6 11 6 7 1 9 4 2 15 0 0 2 2 3 3 4 0 4 33 22 137 0 3 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG13265() 19 25 29 31 0 2 5 4 3 5 2 1 0 4 8 1 8 21 9 5 3 8 12 12 8 47 17 13 5 2 11 5 5 11 28 36 5 2 3 12 4 4 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG1799(Uncharacterized protein conserved in bacteria) 17 5 1 17 4 1 2 0 0 0 0 0 0 1 2 2 14 39 5 1 8 8 20 10 6 68 4 5 7 10 9 4 3 2 7 4 2 131 13 0 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 3 COG3980(Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase) 59 17 34 14 1 3 5 5 4 3 2 2 1 6 4 2 10 12 8 7 11 2 15 4 6 7 2 0 3 3 4 11 5 4 20 29 23 61 9 6 5 5 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG21825() 2 4 11 5 1 1 2 19 40 6 18 10 14 6 4 7 6 5 14 3 13 11 21 18 16 33 0 3 11 4 8 5 9 8 6 13 18 18 12 8 14 2 0 0 0 0 0 0 0 0 0 0 0 0 0 11 COG4323(Predicted membrane protein) 91 34 49 25 0 1 8 8 1 7 2 5 0 12 4 2 1 0 4 5 9 9 14 10 7 10 2 4 6 6 4 14 8 3 34 11 2 8 6 3 2 2 0 0 1 0 0 0 0 0 0 2 0 0 0 2 NOG31410() 2 3 9 2 6 1 5 13 16 6 11 5 1 7 6 5 3 10 6 4 6 13 18 5 6 6 2 12 7 5 6 18 19 12 53 29 0 49 10 15 5 7 0 0 0 0 0 0 0 0 0 6 0 0 0 8 COG2930(Uncharacterized conserved protein) 110 7 26 14 1 5 1 6 3 3 3 4 2 9 6 5 4 2 2 8 4 2 3 1 4 4 3 1 5 3 4 9 7 6 26 20 11 68 7 14 1 6 0 0 0 0 0 0 0 0 0 5 0 0 0 3 COG1254(Acylphosphatases) 77 15 50 25 2 0 2 2 0 0 1 2 1 7 4 0 6 5 3 6 4 7 11 5 7 12 4 6 1 4 3 12 2 3 7 29 25 58 20 4 1 2 0 0 0 0 0 1 0 0 0 2 0 0 0 0 COG1883(Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit) 52 21 23 17 0 3 1 18 10 3 10 8 7 27 11 12 2 0 10 6 7 4 18 5 8 0 7 4 0 5 1 11 5 0 15 28 26 27 7 8 7 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG20563() 66 16 19 22 1 2 3 16 5 4 2 0 2 11 0 4 1 8 3 4 1 9 15 8 3 19 4 5 11 4 7 15 17 21 21 35 2 4 11 18 5 0 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG1833(Uncharacterized conserved protein) 10 30 13 12 0 0 8 4 0 0 0 3 0 0 0 4 5 15 4 20 11 19 16 15 7 0 6 13 7 3 12 21 30 17 32 28 7 0 13 13 4 8 0 0 0 0 0 0 0 0 0 10 0 0 0 16 NOG08023() 60 15 60 23 3 1 0 0 2 0 0 2 4 6 3 7 2 4 3 14 16 13 25 5 16 2 5 7 3 1 9 8 11 8 0 29 6 6 6 24 7 5 0 0 0 0 0 0 0 0 0 4 0 0 0 10 COG5394(Uncharacterized protein conserved in bacteria) 67 6 6 5 0 2 4 2 1 4 1 1 0 8 4 4 16 23 10 2 1 4 1 2 7 21 11 6 2 0 7 14 9 9 16 8 10 115 1 12 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 10 NOG31190() 20 5 5 6 2 12 6 2 0 3 7 2 3 23 4 5 13 12 22 8 3 6 3 2 4 47 4 6 3 6 6 13 6 2 4 18 3 116 4 8 4 2 0 1 0 0 0 0 0 0 0 2 0 0 0 2 COG2509(Uncharacterized FAD-dependent dehydrogenases) 77 2 4 3 6 8 1 0 2 1 6 4 3 6 7 0 28 23 9 6 6 6 3 1 0 55 4 2 1 5 0 10 2 2 8 4 8 82 27 4 1 6 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1261(Flagellar basal body P-ring biosynthesis protein) 119 7 9 11 2 7 3 5 1 2 3 0 1 13 0 1 2 2 7 0 4 0 6 5 4 4 7 8 4 1 5 6 7 3 16 4 7 126 1 9 4 5 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG09735() 384 0 4 3 0 0 0 0 0 2 0 8 0 4 2 0 0 0 1 0 4 0 6 2 0 0 1 0 1 0 0 0 0 0 4 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5545(Predicted P-loop ATPase and inactivated derivatives) 8 6 9 11 4 1 7 16 3 5 6 0 13 7 2 2 1 4 16 2 10 3 14 12 13 8 4 2 3 3 2 7 2 2 4 2 0 188 14 0 5 0 0 0 0 0 0 0 0 0 0 3 0 0 0 10 NOG10083() 5 14 17 11 1 0 1 6 6 1 0 3 2 1 3 0 0 2 1 1 1 5 5 5 5 0 13 14 9 9 5 25 23 11 66 36 8 30 13 40 9 13 0 0 0 0 0 0 0 0 0 4 0 0 0 10 NOG06394() 5 10 9 13 8 4 20 10 6 6 7 2 1 10 4 2 9 10 5 6 12 3 22 12 12 3 5 9 0 0 7 16 11 18 48 20 3 34 12 24 4 2 0 0 0 0 0 0 0 0 0 4 0 0 0 5 NOG09696() 9 24 31 19 0 0 0 6 9 8 7 5 7 19 5 14 7 9 15 13 2 3 7 4 2 30 12 10 0 0 2 6 7 2 34 56 5 15 8 9 6 3 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG0850(Septum formation inhibitor) 88 12 10 13 2 2 1 0 0 0 2 2 0 2 0 1 1 0 0 0 14 11 26 11 17 1 3 4 12 10 10 14 6 2 7 3 0 125 11 1 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 NOG09993() 0 0 4 3 1 2 1 0 0 0 0 0 0 0 0 0 3 0 1 10 12 16 45 31 15 15 16 20 34 36 21 12 25 9 25 5 0 0 13 6 6 11 1 0 0 0 0 0 0 0 0 17 0 0 0 15 NOG08367() 20 17 22 16 1 3 8 3 6 0 1 4 7 1 7 7 1 5 10 17 9 10 24 10 10 1 15 8 7 1 10 10 17 10 22 54 6 6 12 7 6 1 0 0 0 0 0 0 0 0 0 5 0 0 0 14 COG2956(Predicted N-acetylglucosaminyl transferase) 109 24 47 15 1 0 0 5 3 0 1 3 0 16 6 5 24 10 8 0 4 16 7 2 5 9 10 7 5 3 2 5 7 0 4 18 20 24 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07938(Transposase) 320 6 0 0 0 0 0 1 1 0 0 0 1 9 2 0 0 2 5 1 3 0 2 1 0 0 1 0 5 1 0 0 0 0 0 1 12 52 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3686(Predicted membrane protein) 83 14 32 21 0 7 2 5 2 2 2 2 0 4 6 2 6 2 2 4 13 12 24 11 9 9 6 2 13 12 18 15 4 5 7 11 3 24 17 4 1 2 0 0 0 0 0 0 0 0 0 6 0 0 0 3 COG3599(Cell division initiation protein) 18 5 2 1 5 0 4 0 0 0 0 0 0 0 0 3 31 29 9 2 3 3 2 3 3 80 8 11 0 2 3 7 6 1 0 18 2 140 15 7 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3316(Transposase and inactivated derivatives) 33 1 3 2 2 10 2 21 11 17 48 7 7 112 11 12 4 1 39 0 0 0 0 0 3 1 5 0 2 0 0 3 1 11 2 9 23 21 0 1 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3047(Outer membrane protein W) 324 12 10 2 0 0 2 4 0 0 2 0 2 3 4 0 2 7 0 4 2 0 0 1 0 1 3 0 1 0 3 1 1 2 1 6 2 24 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3909(Cytochrome c556) 18 7 4 9 0 1 3 12 9 3 12 11 5 0 11 11 13 20 5 7 6 8 5 2 6 4 4 0 5 0 2 23 6 2 26 15 19 114 4 8 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG04776(Neutral invertase) 31 14 1 27 3 7 0 0 0 0 0 0 2 0 0 0 0 0 0 0 39 17 27 28 29 0 6 6 9 15 29 20 8 2 5 4 2 55 25 2 8 0 0 0 1 0 0 0 0 0 0 5 0 0 0 0 COG1836(Predicted membrane protein) 19 11 36 14 1 7 1 4 2 0 0 1 0 0 3 0 0 0 0 6 25 15 30 25 20 0 6 8 14 11 27 12 15 7 3 6 2 32 21 7 7 4 0 2 0 0 0 0 0 0 0 7 0 0 0 16 COG2740(Predicted nucleic-acid-binding protein implicated in transcription termination) 11 9 5 8 3 6 4 5 3 6 6 1 4 24 4 1 10 1 3 7 10 1 5 6 3 5 10 5 10 4 4 22 16 4 39 8 5 94 19 10 5 4 0 0 0 0 0 0 0 0 0 5 0 0 0 11 COG3108(Uncharacterized protein conserved in bacteria) 40 5 10 5 0 1 1 9 5 8 6 0 4 11 3 0 2 3 7 1 0 2 7 5 9 2 12 7 5 4 4 15 13 13 10 20 6 122 6 23 3 5 1 0 0 0 0 0 0 0 0 4 0 0 0 7 NOG19439() 18 22 20 27 0 1 4 17 3 8 1 6 2 3 5 4 7 7 2 9 9 8 18 12 9 0 4 3 13 1 17 12 17 2 31 37 3 29 10 1 3 5 0 0 0 0 0 0 0 0 0 4 0 0 0 11 COG4784(Putative Zn-dependent protease) 16 15 29 11 5 4 4 7 2 3 8 1 5 18 6 6 11 2 8 15 11 13 25 10 9 1 10 4 5 1 4 15 15 6 14 30 10 44 0 4 1 8 0 0 0 0 0 0 0 0 0 6 0 0 0 3 NOG11725() 217 2 3 0 1 1 1 2 3 0 6 0 2 2 2 1 3 3 5 0 0 0 7 6 1 1 1 3 3 0 0 3 1 0 2 4 0 126 3 3 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1474(Cdc6-related protein, AAA superfamily ATPase) 3 11 28 10 1 2 0 0 1 8 0 9 0 5 12 5 2 2 2 14 16 13 24 4 12 9 10 12 11 7 4 17 22 8 2 23 33 1 5 16 24 13 0 0 0 0 0 0 0 0 0 2 0 0 0 20 COG5398(Heme oxygenase) 10 8 3 13 4 3 1 1 1 0 10 0 0 2 2 0 6 4 3 5 18 15 24 13 12 10 8 16 20 33 14 20 6 5 8 13 0 77 14 7 3 2 0 0 0 0 0 0 0 0 0 5 0 0 0 4 COG4336(Uncharacterized conserved protein) 62 14 21 11 0 4 2 13 6 2 5 11 1 9 7 12 7 6 11 3 3 7 6 3 8 22 6 4 7 1 3 8 9 9 41 24 10 11 4 12 3 12 0 0 0 0 0 0 1 0 0 0 0 0 0 2 NOG38524() 67 26 30 33 1 3 9 6 5 2 3 4 0 14 2 4 5 10 7 6 2 6 9 12 5 9 5 3 11 0 0 9 4 12 21 16 19 22 2 5 4 4 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG3018(Uncharacterized protein conserved in bacteria) 46 11 17 11 3 2 3 5 1 3 2 0 10 10 2 2 2 1 8 12 5 3 15 7 4 0 7 4 11 3 7 9 14 13 21 16 4 81 5 10 8 11 0 0 0 0 0 0 0 0 0 3 0 0 0 10 COG4227(Antirestriction protein) 11 1 0 2 1 0 3 5 0 11 5 0 2 4 0 2 4 4 2 4 0 0 2 0 2 20 4 3 0 1 3 3 6 1 2 4 3 298 0 1 2 4 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG2407(L-fucose isomerase and related proteins) 18 12 17 15 1 2 2 3 5 8 3 2 1 5 8 3 20 13 7 11 6 7 25 4 10 63 8 6 11 0 10 4 10 6 9 23 5 39 11 1 0 3 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG06043() 9 7 32 8 2 4 2 3 9 2 9 6 4 29 8 10 9 4 20 9 5 9 9 1 3 9 3 3 1 0 0 3 3 8 4 15 13 122 5 1 1 13 0 0 0 0 1 0 0 0 0 2 0 0 0 0 COG1620(L-lactate permease) 277 7 7 4 0 1 2 1 0 0 0 0 0 6 6 0 2 12 3 6 5 1 5 3 8 4 11 2 5 1 0 0 4 0 6 0 1 27 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0622(Predicted phosphoesterase) 20 12 28 20 5 3 13 2 9 4 2 2 2 9 6 3 5 4 11 9 4 5 8 5 6 5 7 6 3 2 1 17 11 17 37 35 8 33 5 21 5 0 0 0 0 0 0 0 0 0 0 2 0 4 0 4 NOG08485() 250 4 11 9 1 0 4 7 0 0 0 1 0 2 0 7 1 2 4 4 0 4 4 1 0 9 2 3 3 1 4 4 4 0 4 18 1 23 10 4 5 4 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG37676() 8 11 37 20 1 2 2 1 1 4 4 1 3 36 14 9 11 6 10 9 3 15 9 2 4 23 5 6 3 2 2 9 4 2 7 11 18 90 2 1 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG13018() 4 16 25 14 4 1 12 9 5 3 10 7 0 5 2 3 1 7 5 11 2 11 16 7 9 6 5 11 5 1 7 15 14 10 38 26 5 36 8 16 11 6 0 0 0 0 0 0 0 0 0 2 1 0 0 7 COG2067(Long-chain fatty acid transport protein) 96 10 7 3 0 2 2 2 3 2 13 2 4 15 1 2 4 3 6 3 2 1 3 2 1 3 4 13 0 0 4 6 8 4 18 17 18 108 7 7 1 4 0 0 0 0 0 0 0 0 0 5 0 0 0 2 COG1623(Predicted nucleic-acid-binding protein (contains the HHH domain)) 12 5 11 6 1 0 9 0 1 0 0 2 0 6 5 12 5 3 8 13 14 5 19 9 12 1 14 15 23 0 9 12 14 16 29 56 4 0 21 5 12 6 0 0 0 0 0 0 0 0 0 3 0 0 0 20 COG2187(Uncharacterized protein conserved in bacteria) 82 2 9 4 0 1 2 2 0 0 0 0 2 2 0 0 1 4 1 1 4 0 1 2 2 1 6 6 0 0 1 0 0 0 0 2 34 246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19826() 4 30 53 33 1 0 7 7 4 1 0 5 3 11 7 4 0 0 1 10 5 4 11 7 5 1 9 10 7 5 2 13 18 9 56 28 4 6 3 10 6 4 2 0 0 0 0 2 0 0 0 4 0 0 0 6 COG1928(Dolichyl-phosphate-mannose--protein O-mannosyl transferase) 1 5 17 11 1 0 1 2 0 2 3 0 2 5 0 1 49 38 0 14 4 1 6 4 0 149 2 4 0 1 0 5 1 0 4 9 7 67 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG04727(Chlorophyll protein) 22 7 1 34 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 9 57 40 34 0 3 4 28 35 22 19 1 3 4 10 1 0 29 6 2 6 0 0 0 0 0 0 0 0 0 8 0 0 0 1 NOG08456() 24 5 4 24 1 1 1 2 0 0 0 0 0 0 2 1 5 1 0 2 18 7 27 9 13 5 0 5 16 17 12 10 4 5 13 5 1 151 15 5 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 2 NOG11886(Probable transmembrane protein) 104 8 15 11 3 2 8 3 6 4 2 9 5 6 2 6 9 20 12 4 3 5 5 4 11 3 1 7 8 2 3 6 9 6 13 18 0 48 6 5 1 4 0 0 0 0 0 0 0 0 0 4 0 0 0 5 COG4880(Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats) 2 2 11 1 1 1 1 2 0 5 0 11 0 12 3 3 4 2 12 1 9 34 20 8 5 0 1 8 12 20 6 10 47 18 6 40 18 28 5 9 16 2 0 0 0 0 0 0 0 0 0 1 0 0 0 19 COG5465(Uncharacterized conserved protein) 10 16 25 18 2 5 8 5 2 4 4 2 2 8 4 2 3 0 5 6 11 7 14 7 9 0 15 11 10 0 3 12 12 8 28 34 3 56 12 15 1 8 0 0 0 0 0 0 0 0 0 2 0 0 0 7 COG0814(Amino acid permeases) 278 8 15 6 8 7 0 0 0 4 0 0 0 5 0 0 0 4 3 2 1 0 6 2 5 6 5 1 0 12 0 0 0 0 1 6 21 7 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2119(Predicted membrane protein) 115 4 5 13 3 5 7 0 0 2 0 0 0 0 0 0 9 6 0 5 19 5 18 12 12 25 0 4 9 20 12 8 0 0 2 1 0 67 17 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 3 0 COG1625(Fe-S oxidoreductase, related to NifB/MoaA family) 24 15 18 33 1 3 5 0 0 0 0 0 0 0 2 3 2 0 2 1 30 10 26 20 22 5 9 11 19 18 10 12 4 3 8 12 4 46 27 0 3 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 COG3693(Beta-1,4-xylanase) 11 3 5 9 24 6 18 18 3 13 1 2 15 0 4 3 0 3 3 10 1 9 16 12 7 3 2 15 16 5 7 13 9 10 41 29 6 5 6 31 5 9 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG1035(Coenzyme F420-reducing hydrogenase, beta subunit) 8 4 6 3 2 1 2 3 1 8 0 0 0 6 0 3 16 9 2 4 4 8 9 5 0 61 10 3 1 0 5 4 5 8 21 66 4 102 2 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 13 NOG11998() 31 13 25 21 4 3 2 14 1 4 2 2 4 17 2 5 5 0 2 10 2 8 13 8 9 0 9 9 5 5 4 8 8 8 23 22 20 49 6 10 1 3 0 0 0 0 0 0 0 0 0 5 0 0 0 10 NOG18717() 13 11 3 13 1 3 5 15 1 1 0 4 3 13 2 7 4 5 12 5 10 12 5 6 12 0 16 7 6 4 1 11 13 8 29 30 0 69 5 24 3 5 0 0 0 0 0 0 0 0 0 2 0 0 0 12 NOG19670() 13 13 20 11 1 1 3 4 12 8 4 5 2 7 2 5 4 10 4 0 9 10 9 4 2 31 6 8 4 2 2 6 20 6 29 24 7 35 12 31 7 8 0 0 0 0 0 0 0 0 0 3 0 0 0 7 COG3158(K+ transporter) 119 0 0 0 0 0 2 6 0 2 2 1 2 10 13 6 43 37 6 0 1 0 2 0 1 127 7 0 0 1 1 1 1 0 2 11 0 2 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1956(GAF domain-containing protein) 61 6 20 4 6 4 3 5 4 1 7 2 1 19 2 6 4 0 6 4 0 13 8 8 5 10 16 10 8 0 6 23 13 5 18 17 9 38 10 10 3 4 0 0 0 0 0 0 0 0 0 1 0 0 0 10 COG1649(Uncharacterized protein conserved in bacteria) 33 8 31 7 4 1 5 7 4 2 4 0 0 1 0 4 4 9 3 4 7 8 10 8 2 14 10 14 3 2 2 13 7 2 20 11 4 93 26 3 6 5 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG5605(Predicted small integral membrane protein) 55 47 48 64 1 2 6 5 0 0 0 10 1 4 2 0 0 0 2 4 10 8 15 8 5 0 0 2 3 0 0 3 1 5 9 75 3 1 1 4 2 0 0 0 0 1 0 0 0 0 0 1 0 0 0 2 COG1786(Uncharacterized conserved protein) 45 9 18 14 0 2 2 0 2 7 1 7 6 13 4 4 2 3 1 13 5 11 17 12 10 15 8 11 10 3 6 17 16 9 28 8 2 7 8 14 7 4 0 0 0 0 0 0 0 0 0 6 0 0 0 22 NOG10781() 2 16 91 32 2 3 0 1 1 0 0 1 0 6 3 0 4 2 2 8 10 26 18 6 8 7 12 8 14 1 14 4 2 0 0 7 15 34 2 6 7 14 0 0 0 0 0 0 0 0 0 8 0 0 0 12 NOG08475() 23 11 1 27 1 5 5 1 0 0 0 0 0 0 0 0 0 0 0 1 28 8 37 21 35 0 0 16 20 25 37 16 1 0 8 0 0 42 31 1 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG27438() 0 4 2 8 13 2 17 7 8 0 4 4 4 2 4 7 7 8 2 11 8 2 10 7 10 9 6 18 2 0 8 7 18 14 42 37 8 32 1 22 10 10 0 0 0 0 0 0 0 1 0 0 0 0 0 12 COG1842(Phage shock protein A (IM30), suppresses sigma54-dependent transcription) 171 12 10 3 2 1 1 3 3 7 2 2 7 9 2 2 0 2 5 1 4 0 10 3 2 1 1 1 3 4 3 7 3 5 6 3 6 77 15 0 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG1362(Aspartyl aminopeptidase) 7 7 8 4 6 0 1 1 3 5 13 0 8 11 3 6 5 12 12 10 4 8 9 5 5 41 5 2 4 3 2 1 3 0 0 13 13 160 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16584(Sulfotransferase) 12 8 21 8 5 2 1 6 1 0 5 1 4 6 20 0 0 2 5 6 9 16 11 4 0 10 3 2 3 6 1 12 3 2 6 36 17 115 12 9 7 7 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG38429() 9 18 18 23 0 0 0 5 1 0 3 2 3 3 8 1 0 4 6 7 13 6 12 12 19 1 10 13 14 3 11 14 22 18 22 55 12 0 4 9 10 3 0 0 0 0 0 0 0 0 0 2 0 0 0 10 COG1346(Putative effector of murein hydrolase) 149 3 3 0 1 0 0 6 1 2 9 5 0 15 1 3 23 14 10 0 2 0 1 1 0 31 1 1 0 1 4 2 3 0 7 0 15 86 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25410() 5 4 8 9 0 13 4 16 2 4 1 0 0 14 1 1 9 4 15 4 5 2 11 5 0 29 8 7 1 3 3 6 2 0 13 10 2 169 8 4 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2959(Uncharacterized enzyme of heme biosynthesis) 153 9 2 2 4 3 3 13 5 0 9 1 2 8 4 2 9 2 13 2 1 0 2 2 0 4 2 5 1 0 2 0 3 4 5 5 13 104 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1359(Uncharacterized conserved protein) 100 13 28 22 0 3 8 1 1 8 0 3 3 14 2 6 2 1 13 12 7 4 10 11 7 4 5 0 9 5 2 7 11 0 12 30 1 22 3 7 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG3407(Mevalonate pyrophosphate decarboxylase) 5 13 42 12 8 1 9 0 5 2 2 2 3 10 4 4 2 6 6 5 3 4 9 6 2 6 4 7 0 2 8 16 17 7 33 30 22 26 11 26 5 7 0 0 0 0 0 0 0 1 0 9 0 1 0 1 NOG09905() 17 45 46 30 1 0 4 1 3 1 0 1 3 0 6 3 0 0 7 8 7 7 23 10 1 2 2 6 12 2 12 23 4 3 47 20 2 6 11 8 1 8 0 0 0 0 0 0 0 0 0 7 0 0 0 4 NOG12572(Secreted protein) 15 21 39 13 0 1 1 1 0 1 1 1 1 3 2 1 25 12 3 4 7 10 12 3 3 63 11 8 4 2 0 14 16 7 23 17 4 20 7 4 4 0 0 0 0 0 0 0 0 0 2 2 0 0 0 16 NOG08787(Nitrile hydratase alpha subunit) 52 19 12 19 1 3 5 4 2 9 1 1 2 25 2 4 1 0 2 3 3 4 12 10 8 4 12 11 6 2 2 13 10 6 30 19 5 31 14 15 3 6 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG1691(NCAIR mutase (PurE)-related proteins) 27 17 14 35 3 3 2 5 0 5 0 1 0 7 8 2 4 0 4 9 12 16 29 12 25 20 5 3 16 15 12 9 5 4 0 13 1 30 19 4 1 1 0 0 0 0 1 0 0 0 0 3 0 0 0 2 COG5467(Uncharacterized conserved protein) 29 51 25 44 0 0 5 4 0 1 0 0 1 1 0 1 15 18 2 9 9 11 11 5 4 8 4 5 4 1 4 4 3 4 16 65 2 28 1 3 0 2 0 0 0 0 0 0 1 0 0 1 0 0 0 1 COG2356(Endonuclease I) 49 15 23 4 5 7 5 11 4 2 5 6 7 2 0 4 2 4 7 11 0 2 11 2 17 4 11 9 3 11 7 13 13 16 22 9 4 35 2 25 3 2 0 0 0 0 2 0 0 0 0 0 0 0 0 7 COG0383(Alpha-mannosidase) 15 5 33 15 6 14 9 2 0 0 1 1 0 1 2 0 6 3 3 2 9 12 11 5 8 18 13 4 0 11 2 14 14 4 6 10 0 84 47 3 2 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 COG3703(Uncharacterized protein involved in cation transport) 52 9 12 7 1 4 3 6 2 9 4 1 4 15 3 1 9 2 13 6 7 1 10 3 12 3 11 4 2 3 7 12 7 6 27 18 2 62 12 16 8 3 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG1904(Glucuronate isomerase) 15 17 12 6 9 9 7 1 6 3 6 8 1 18 8 4 8 4 21 7 1 4 10 9 8 15 20 11 7 9 6 11 0 6 31 16 10 29 4 10 3 1 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG14448() 4 18 36 8 9 1 8 10 4 1 4 6 7 6 9 1 0 1 7 9 14 8 11 9 9 2 6 8 7 2 6 15 10 11 35 52 4 9 3 17 5 3 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG05601(EC 6.3.2.- Auxin-responsive GH3-like protein) 93 10 6 4 4 0 5 3 5 4 0 10 4 0 6 2 4 4 0 3 5 10 12 4 2 0 13 14 8 7 0 14 18 10 24 28 6 18 9 15 9 0 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG16635() 12 15 23 16 0 1 1 5 2 0 1 7 5 5 10 6 6 3 4 4 17 6 12 3 6 7 9 6 8 0 10 20 13 7 36 62 18 0 6 9 5 4 0 0 0 0 0 0 0 2 0 1 0 0 0 6 COG5492(Bacterial surface proteins containing Ig-like domains) 72 10 40 13 1 1 8 0 2 0 6 7 0 0 0 4 4 2 4 3 10 18 13 18 10 22 11 4 5 2 7 4 6 2 4 3 3 48 6 10 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 10 COG3968(Uncharacterized protein related to glutamine synthetase) 1 1 9 5 8 3 4 4 11 1 12 7 8 0 2 4 8 14 11 4 1 1 4 0 2 53 2 2 4 7 0 13 2 5 13 9 14 132 5 5 3 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 NOG04707(Photosystem II protein) 36 10 9 16 4 10 3 0 0 0 0 0 1 2 0 4 0 0 1 2 22 20 32 23 20 0 2 6 15 32 24 22 4 4 8 0 1 29 26 1 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG17129() 95 12 33 7 0 0 0 2 5 3 7 0 2 7 2 5 6 3 3 5 7 6 4 2 6 0 8 4 6 0 0 10 6 5 13 22 0 86 4 2 3 4 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3024(Uncharacterized protein conserved in bacteria) 72 9 13 12 2 1 1 4 0 3 10 0 3 15 3 3 12 1 10 4 3 2 5 3 4 12 3 1 1 3 1 7 5 2 14 12 10 119 4 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG24959() 10 5 8 8 2 10 1 7 3 6 4 2 0 21 1 1 5 4 17 6 4 9 16 4 5 22 4 3 2 3 6 10 7 6 2 18 4 130 5 2 2 6 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG1577(Mevalonate kinase) 10 10 38 11 0 1 1 0 2 0 0 2 0 11 4 0 6 9 3 6 4 22 11 4 5 23 6 5 5 1 3 13 20 10 14 31 29 15 7 14 18 3 0 0 0 0 0 0 2 0 0 3 0 0 0 14 NOG16025(Integral membrane protein) 5 5 2 5 0 0 1 0 0 0 0 0 0 2 0 0 10 20 3 9 6 2 9 6 9 60 4 7 6 0 0 6 2 9 4 23 0 164 5 0 7 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG3668(Plasmid stabilization system protein) 162 19 0 1 1 0 0 0 0 0 0 1 0 1 0 0 4 2 0 0 0 0 0 1 0 3 1 1 2 0 0 0 0 0 0 0 28 169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24971() 8 18 34 19 0 0 6 13 1 0 6 5 7 13 8 3 5 4 0 4 3 7 5 3 9 6 1 6 3 3 5 16 20 10 43 45 4 0 9 20 7 7 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG1287(Uncharacterized membrane protein, required for N-linked glycosylation) 0 7 30 9 8 9 0 2 0 3 0 2 2 9 8 0 2 2 11 11 20 24 17 3 6 16 6 8 2 10 2 9 34 16 4 13 23 2 3 14 21 5 1 0 0 0 2 0 0 0 0 4 0 0 0 15 COG2608(Copper chaperone) 197 1 5 0 1 0 0 0 0 0 2 1 0 4 0 0 6 9 1 3 0 2 0 0 3 12 2 2 0 2 4 1 0 0 2 0 5 129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19695() 9 25 8 21 2 3 6 10 4 5 0 5 2 5 11 4 5 13 4 5 7 8 18 7 4 0 7 3 4 1 12 14 19 5 25 42 10 11 7 13 6 8 0 0 0 0 0 0 0 0 0 5 1 0 0 10 NOG08884() 10 15 29 7 4 2 4 3 2 0 2 8 0 15 2 6 4 2 2 6 6 13 8 3 4 17 8 9 3 0 7 15 14 5 40 47 8 24 7 14 3 3 0 0 0 0 0 0 0 0 0 6 0 0 0 7 NOG08036() 5 35 33 25 8 2 4 13 1 5 0 8 6 12 6 4 6 0 12 8 1 4 14 10 9 1 10 11 9 8 2 11 5 20 32 31 0 0 6 6 1 6 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3429(Glucose-6-P dehydrogenase subunit) 27 7 1 13 5 3 1 0 0 0 0 0 0 2 0 0 2 6 1 2 24 9 20 21 23 7 1 6 17 14 19 14 1 2 0 4 0 114 20 0 4 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 NOG13926() 5 5 11 15 6 0 6 9 7 2 1 0 6 2 2 3 5 4 1 18 7 7 15 7 18 52 7 17 11 11 5 5 15 10 22 18 2 7 21 8 7 2 0 0 0 0 0 0 0 0 0 1 0 0 0 10 COG2988(Succinylglutamate desuccinylase) 139 9 1 32 2 4 2 1 0 0 0 0 0 0 0 0 0 0 1 0 12 8 22 9 9 1 10 6 15 15 18 14 2 4 0 0 2 32 19 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG26244() 10 4 12 8 3 10 0 6 1 3 9 3 5 8 2 1 3 0 16 2 6 8 5 1 1 28 6 5 1 14 0 7 5 0 5 12 0 168 7 3 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG3040(Bacterial lipocalin) 68 14 23 12 2 1 2 3 6 4 18 2 3 11 12 6 10 6 12 9 7 13 14 2 10 23 7 4 4 2 2 9 6 1 7 8 4 35 2 4 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3397(Uncharacterized protein conserved in bacteria) 199 7 15 7 0 0 1 0 2 0 0 2 0 0 6 11 0 4 0 4 4 3 2 2 8 3 4 0 0 1 0 4 2 2 4 10 3 53 2 8 3 2 0 0 0 0 0 0 0 0 0 12 0 0 0 2 NOG23396() 3 12 49 11 5 2 3 18 7 2 1 7 0 8 4 3 2 0 8 2 8 14 14 7 3 8 11 12 5 0 8 15 9 4 40 43 0 3 3 18 8 0 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG3814(Uncharacterized protein conserved in bacteria) 15 18 10 16 1 5 2 6 3 1 1 1 0 13 6 4 0 0 8 4 6 5 10 5 10 1 12 6 7 0 6 14 9 12 34 29 8 56 12 15 3 6 0 0 0 0 0 0 0 0 0 6 0 0 0 5 NOG06395() 4 1 7 1 16 0 6 10 22 0 1 8 2 2 4 2 6 2 10 5 2 10 10 4 4 1 6 19 4 1 4 14 9 14 48 34 7 19 11 30 17 6 0 0 0 0 0 0 0 0 0 0 0 0 0 8 NOG11860() 7 14 20 23 1 1 3 3 3 5 3 6 0 47 16 8 6 1 6 9 11 12 27 17 5 5 7 7 13 3 3 6 6 4 22 16 19 6 3 8 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG17710() 7 4 8 5 18 2 4 11 6 2 4 10 5 6 4 3 10 7 8 4 2 9 16 4 3 15 6 13 9 0 2 10 13 10 22 24 9 32 10 25 5 8 0 0 0 0 1 0 0 1 0 1 0 0 0 11 NOG15748() 1 5 16 6 1 3 0 0 0 6 0 3 2 6 0 0 1 6 6 8 10 5 9 5 0 0 3 2 15 6 0 10 13 4 7 22 15 173 2 6 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG2013(Uncharacterized conserved protein) 32 13 14 6 4 4 0 2 6 0 1 2 2 8 2 2 0 0 2 11 7 14 20 4 12 13 0 5 5 7 4 4 2 2 11 10 15 114 1 16 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 5 COG1493(Serine kinase of the HPr protein, regulates carbohydrate metabolism) 77 5 4 3 2 3 1 0 0 1 7 0 3 20 2 2 13 20 7 4 2 3 1 1 3 26 10 1 9 4 5 5 5 2 16 11 10 66 6 9 1 10 0 0 0 1 0 0 0 0 0 2 0 0 0 5 NOG17693(Prolyl 4-hydroxylase, alpha subunit) 23 26 16 19 1 6 7 19 15 6 3 6 13 24 7 7 8 7 2 4 4 5 16 12 7 1 5 9 8 8 0 8 11 5 27 11 2 0 4 7 5 6 0 0 0 0 0 0 0 0 0 2 0 0 0 6 NOG07893() 21 8 7 11 0 3 3 8 13 15 0 11 0 2 8 0 4 4 1 4 1 9 18 15 11 1 27 16 3 0 15 7 2 6 47 34 6 5 6 3 3 8 0 0 0 0 0 0 0 0 0 9 0 0 0 13 COG2807(Cyanate permease) 170 1 6 1 0 0 0 2 2 0 2 2 2 2 0 1 2 7 3 0 3 0 0 0 0 5 0 0 1 0 0 2 0 0 2 5 15 151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1269(Archaeal/vacuolar-type H+-ATPase subunit I) 0 9 20 5 2 2 0 0 6 0 0 0 1 5 4 5 4 0 2 18 13 10 14 1 3 33 7 7 5 11 0 7 22 3 0 17 35 50 2 15 15 10 0 0 0 0 0 0 0 0 0 2 0 0 0 22 COG3161(4-hydroxybenzoate synthetase (chorismate lyase)) 107 32 20 19 2 1 2 6 1 0 8 1 3 28 6 3 9 1 5 3 6 1 5 5 3 0 3 4 1 3 3 11 8 4 23 23 9 2 4 4 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG0786(Na+/glutamate symporter) 82 9 2 20 1 4 2 2 0 0 0 0 7 7 0 1 0 0 4 3 13 5 31 33 26 6 5 9 14 23 20 9 4 2 2 1 4 15 6 0 0 2 0 0 0 0 0 0 0 0 0 9 0 0 0 3 NOG13388(Transcriptional regulator protein) 56 11 7 16 5 7 4 4 0 1 3 2 0 8 0 1 7 6 1 0 20 3 13 10 18 8 6 15 9 6 16 9 6 6 19 4 18 28 16 2 3 4 0 0 0 0 0 0 0 0 0 6 0 0 0 2 NOG04740() 22 7 3 28 0 6 0 0 0 0 0 0 2 0 0 0 0 0 0 3 36 12 37 26 41 0 5 4 17 20 26 11 3 3 9 4 0 22 34 0 0 0 0 0 0 2 0 0 0 0 0 2 0 1 0 0 COG2954(Uncharacterized protein conserved in bacteria) 15 7 35 18 13 2 1 2 2 0 4 1 0 3 0 1 4 5 5 7 16 10 33 18 23 3 8 10 8 6 15 16 17 7 10 8 0 20 14 10 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG1163(Predicted GTPase) 5 17 37 17 3 4 0 9 5 3 0 2 0 0 4 1 4 4 2 6 5 13 25 19 8 11 19 3 7 2 5 10 9 8 12 20 26 17 7 10 8 5 0 0 0 0 0 0 1 0 0 3 0 0 0 9 COG1029(Formylmethanofuran dehydrogenase subunit B) 149 20 9 17 0 0 1 5 6 0 2 3 1 0 7 1 3 4 2 5 2 8 4 5 4 5 6 4 5 0 1 7 5 0 15 28 3 28 6 4 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG5433(Transposase) 41 17 1 0 0 0 0 0 0 0 0 0 0 2 0 1 0 2 3 0 0 0 0 1 0 3 0 0 1 2 1 2 0 0 0 0 30 276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3733(Cu2+-containing amine oxidase) 8 11 19 9 3 3 5 6 4 4 0 0 2 5 0 4 19 21 3 6 5 3 15 8 15 28 10 10 5 4 0 19 11 4 30 29 3 25 2 4 4 10 0 0 0 0 0 0 0 0 0 5 0 0 0 3 COG4668(Mannitol/fructose-specific phosphotransferase system, IIA domain) 40 3 8 9 0 0 8 2 1 0 0 4 0 11 0 5 0 5 9 4 5 4 15 1 2 5 7 7 5 1 0 5 17 16 37 34 1 69 11 8 5 5 0 0 0 0 0 0 0 0 0 3 0 0 0 11 COG4983(Uncharacterized conserved protein) 37 11 15 12 1 3 1 25 2 3 17 2 0 3 0 0 9 8 21 4 6 2 9 9 1 10 11 0 1 6 0 9 7 6 6 7 2 109 2 2 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4451(Ribulose bisphosphate carboxylase small subunit) 15 11 3 19 2 2 3 0 0 1 2 0 0 3 1 6 1 2 2 1 14 11 21 10 19 5 3 1 18 12 13 8 3 3 8 12 1 130 6 3 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG13134() 321 5 3 2 6 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 1 0 0 3 0 0 0 2 2 0 0 0 0 0 0 31 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36704() 0 13 5 10 4 2 16 9 3 0 8 9 9 0 12 3 2 6 7 4 3 7 6 10 9 10 4 5 10 1 4 20 9 12 42 54 4 0 5 27 7 6 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG3504(Type IV secretory pathway, VirB9 components) 351 2 4 1 0 0 0 0 0 0 0 0 0 2 0 0 2 1 0 0 0 0 1 0 0 0 2 0 0 1 0 1 0 0 0 0 2 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12626(Transcription protein) 6 4 2 2 0 0 9 11 0 0 0 1 2 3 6 6 25 24 5 13 8 1 20 3 1 67 9 5 11 0 7 9 12 9 3 18 0 42 5 4 6 5 0 0 0 0 0 0 0 0 0 4 0 0 0 12 NOG05640(Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-)) 1 9 16 5 0 0 0 7 6 2 0 2 5 0 4 3 0 2 4 0 4 7 10 1 4 0 8 12 15 4 14 35 15 9 51 34 9 5 5 36 10 8 0 0 0 0 0 0 0 0 0 9 0 0 0 7 COG0387(Ca2+/H+ antiporter) 106 7 8 4 3 3 2 0 1 1 0 4 6 11 4 2 5 3 2 3 3 8 15 4 1 3 2 6 5 3 0 5 3 2 0 14 2 102 6 3 4 0 0 0 2 0 0 0 0 0 0 1 1 0 0 8 COG5078(Ubiquitin-protein ligase) 2 6 32 11 17 27 3 2 7 6 3 0 0 5 2 9 17 14 7 6 9 6 21 10 9 9 5 5 5 19 2 6 11 11 12 21 11 17 3 3 1 0 0 0 0 0 0 0 0 0 0 1 0 1 0 4 NOG09954() 3 3 6 5 12 4 6 3 13 0 9 2 4 2 4 4 4 8 3 4 6 6 4 5 5 7 6 2 5 2 4 16 16 6 53 39 2 28 8 30 8 6 0 0 0 0 0 0 0 0 0 5 0 0 0 9 COG3186(Phenylalanine-4-hydroxylase) 108 6 27 3 1 2 2 1 2 6 3 1 0 2 10 0 4 2 3 6 0 10 4 3 9 26 5 4 3 2 3 14 2 2 24 23 10 19 2 11 4 6 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG18954() 50 7 20 20 1 4 3 8 4 4 5 0 6 9 3 3 4 2 11 10 8 5 15 14 7 13 13 6 8 0 1 3 8 5 21 11 2 5 22 24 2 2 2 0 0 0 0 1 0 0 0 1 0 0 0 4 COG2077(Peroxiredoxin) 82 9 8 6 0 1 1 3 2 4 2 4 0 11 9 1 2 13 4 3 2 5 6 0 1 32 3 0 1 3 2 4 2 0 4 10 19 111 2 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4658(Predicted NADH:ubiquinone oxidoreductase, subunit RnfD) 41 3 3 2 3 0 3 4 1 2 7 4 2 3 2 3 11 13 7 0 1 4 4 4 4 3 6 1 1 1 0 6 1 8 9 3 21 181 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4098(Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)) 174 5 13 4 0 0 0 0 0 2 1 0 0 0 0 4 6 2 0 0 6 2 3 2 0 41 0 0 0 0 0 1 2 0 8 9 4 84 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1920(Uncharacterized conserved protein) 9 12 25 9 2 0 7 4 4 0 0 3 3 10 13 6 2 8 2 8 14 7 17 5 5 22 5 9 9 0 14 13 5 14 8 38 4 20 10 13 3 5 0 0 0 0 0 0 0 0 0 3 0 0 0 5 COG2508(Regulator of polyketide synthase expression) 71 3 1 0 0 0 0 0 2 0 2 0 0 10 0 3 4 12 6 2 0 0 1 1 0 4 0 0 3 1 0 0 0 0 1 0 17 228 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG10090(Nitrile hydratase beta subunit) 55 14 13 24 2 5 6 5 1 7 1 1 1 21 2 3 0 0 5 4 3 4 9 7 6 3 14 8 5 2 1 11 7 8 14 17 4 30 15 16 3 5 0 0 0 0 0 0 0 0 0 3 0 0 0 10 NOG25312() 3 9 18 8 9 0 6 2 1 4 2 1 2 2 0 2 2 1 2 7 5 14 17 3 9 3 16 8 3 0 8 22 10 6 39 35 9 27 8 22 7 6 0 0 0 0 0 0 0 1 0 4 0 0 0 12 COG2766(Putative Ser protein kinase) 139 6 2 2 2 5 2 0 4 0 0 0 2 2 4 1 7 6 2 4 6 4 5 9 0 22 5 0 15 4 4 5 0 0 0 16 26 44 8 3 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG3712(Fe2+-dicitrate sensor, membrane component) 168 20 21 4 1 0 0 5 3 1 4 1 2 2 0 2 1 1 5 1 4 3 0 1 2 10 13 5 2 1 1 6 10 6 8 11 9 3 8 19 6 0 0 0 0 0 2 0 0 2 0 1 0 0 0 0 COG2961(Protein involved in catabolism of external DNA) 114 7 7 7 0 2 2 4 0 5 2 2 2 3 0 0 20 36 7 0 2 1 4 0 2 33 4 2 3 4 1 5 4 5 4 12 16 45 1 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2995(Uncharacterized paraquat-inducible protein A) 283 9 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 0 0 0 0 2 0 0 0 2 1 0 4 0 0 0 0 0 2 6 53 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1863(Multisubunit Na+/H+ antiporter, MnhE subunit) 11 10 12 7 1 3 9 0 2 5 8 4 3 7 2 5 2 0 3 2 2 6 19 9 16 0 11 6 3 1 3 4 4 2 18 13 13 136 7 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG10067() 2 4 1 5 3 4 10 14 1 11 22 3 12 10 4 4 4 16 11 7 4 8 16 9 8 5 12 12 6 5 3 23 7 14 20 11 1 29 13 10 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG11483() 106 14 12 17 0 2 0 6 7 4 2 3 4 24 19 5 1 0 7 6 4 7 4 1 2 3 1 5 1 0 1 8 5 2 25 28 7 14 3 6 1 2 0 0 0 0 1 0 0 0 0 0 0 0 0 2 COG2345(Predicted transcriptional regulator) 37 1 3 0 0 1 1 0 0 0 1 0 0 4 0 0 29 58 2 4 3 1 2 2 1 94 2 0 1 4 0 8 2 4 0 5 0 84 13 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG21649() 0 10 22 7 1 5 5 21 5 6 9 1 13 11 2 7 2 7 18 3 0 4 11 2 9 3 11 4 2 11 8 10 7 4 4 6 2 101 2 1 1 8 0 0 0 0 1 0 0 0 0 2 0 0 0 2 COG2337(Growth inhibitor) 89 0 2 1 1 1 2 0 0 2 0 0 1 2 0 1 9 9 4 0 0 0 1 0 0 10 3 0 0 0 0 1 0 0 2 3 13 213 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11197(Protein involved in glycosaminoglycan degradation) 17 23 24 15 1 3 18 9 5 0 0 4 3 7 0 3 11 2 1 7 2 4 9 7 10 22 4 18 4 0 4 17 15 12 24 16 0 8 15 8 7 2 0 0 0 0 0 0 0 0 0 3 0 0 0 7 NOG33422() 2 4 10 6 0 1 6 13 10 1 9 6 4 11 3 3 19 3 6 3 3 9 10 3 0 8 9 7 6 0 3 20 14 6 42 26 6 28 4 20 6 5 0 0 0 0 0 0 0 0 0 9 0 0 0 7 NOG06416() 1 4 6 4 44 1 9 5 15 2 0 0 2 4 2 6 8 1 7 5 3 7 7 3 2 21 3 4 6 1 1 14 21 11 53 25 0 19 6 16 15 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3774(Mannosyltransferase OCH1 and related enzymes) 5 0 8 9 2 5 4 23 16 5 7 1 10 8 2 11 17 18 7 19 6 1 15 6 8 28 3 3 2 2 1 2 8 8 2 21 3 53 10 4 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG14371(Acyl-Coa dehydrogenase) 20 18 17 20 1 4 2 9 4 3 2 3 5 9 6 12 6 3 6 7 9 8 9 8 6 3 9 13 5 1 2 10 8 10 26 9 2 41 11 8 2 6 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG5345(Uncharacterized protein conserved in bacteria) 45 10 6 6 0 1 1 7 2 2 12 1 3 15 2 3 0 0 6 0 0 2 6 2 5 0 4 3 6 0 0 3 4 4 16 5 8 171 3 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11651() 2 5 4 4 11 0 8 5 12 16 12 5 9 2 9 7 5 3 9 2 8 8 5 1 0 5 9 3 3 0 1 20 5 8 35 37 5 15 6 38 11 6 0 0 0 0 0 0 0 0 0 5 0 0 0 4 NOG06101() 9 11 46 11 2 0 0 8 1 5 2 4 3 8 5 0 2 3 3 3 12 9 15 8 9 100 4 5 5 1 4 10 11 0 8 8 0 16 1 5 3 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG5520(O-Glycosyl hydrolase) 65 2 13 5 16 11 5 10 10 5 3 3 3 4 8 2 5 9 9 6 2 12 12 4 12 1 14 5 2 4 3 12 10 2 26 7 8 2 4 20 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0170(Dolichol kinase) 17 16 46 19 2 3 1 0 0 0 2 0 0 0 2 0 0 1 1 4 20 15 30 18 17 3 12 5 6 7 26 9 3 2 2 6 8 33 17 2 3 2 0 0 0 0 0 0 0 0 0 8 0 0 0 0 COG3008(Paraquat-inducible protein B) 249 9 5 0 0 3 0 0 1 0 0 3 0 7 6 2 7 6 2 0 0 2 0 1 0 2 5 0 1 7 0 0 0 0 0 1 3 41 1 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG3394(Uncharacterized protein conserved in bacteria) 56 2 12 9 0 1 3 4 0 0 2 7 1 2 2 0 10 7 5 5 8 4 3 5 2 38 3 4 5 3 5 11 4 0 35 28 8 35 18 13 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG2971(Predicted N-acetylglucosamine kinase) 79 7 2 2 0 1 1 1 1 1 0 0 2 0 0 0 12 23 0 2 0 5 2 2 1 23 4 2 3 12 2 12 0 0 0 4 0 122 27 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 7 COG0710(3-dehydroquinate dehydratase) 17 13 14 16 3 2 1 4 1 0 4 0 0 12 6 1 10 9 6 3 5 8 11 5 13 9 8 2 1 3 2 17 9 12 4 18 11 65 14 5 7 4 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG3582(Predicted nucleic acid binding protein containing the AN1-type Zn-finger) 50 9 24 16 4 1 9 5 3 1 0 2 1 5 2 3 11 0 1 1 6 7 10 4 1 22 8 6 4 4 10 7 6 0 16 30 7 36 3 18 3 6 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG1534(Predicted RNA-binding protein containing KH domain, possibly ribosomal protein) 66 2 15 5 1 1 0 5 8 1 5 3 2 13 14 5 14 11 7 3 2 0 3 2 3 16 2 4 1 2 2 3 3 2 6 20 12 89 0 6 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG5534(Plasmid replication initiator protein) 211 0 3 2 1 0 0 2 1 0 0 0 0 2 0 0 0 0 2 0 0 0 1 0 0 4 0 0 2 0 1 0 0 0 0 0 2 132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0549(Carbamate kinase) 32 8 52 19 1 0 0 0 0 0 0 2 0 1 6 1 0 0 0 18 9 18 13 21 13 1 8 13 3 2 4 9 12 8 13 22 9 5 3 10 8 6 0 0 0 0 0 0 0 0 0 2 0 0 0 13 COG1528(Ferritin-like protein) 54 7 10 10 2 6 0 3 1 0 3 1 1 0 2 0 3 0 1 3 9 17 19 10 19 3 1 5 5 8 7 25 3 4 4 15 7 69 17 4 1 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 COG4095(Uncharacterized conserved protein) 34 11 14 8 5 1 4 6 10 8 2 12 0 13 2 8 7 2 1 7 16 5 19 7 12 17 3 10 11 8 12 13 5 2 16 19 6 3 4 2 5 4 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG3470(Uncharacterized protein probably involved in high-affinity Fe2+ transport) 55 8 30 15 2 0 5 4 9 1 0 4 0 2 2 0 0 0 0 2 1 3 11 6 1 0 1 1 6 1 3 27 17 16 57 24 1 0 6 21 6 7 0 0 0 0 0 0 0 0 0 7 0 0 0 2 COG2893(Phosphotransferase system, mannose/fructose-specific component IIA) 48 11 9 14 0 1 0 14 1 2 3 1 3 13 0 3 7 8 8 3 5 6 1 2 2 15 11 1 3 1 2 11 7 2 24 16 8 64 7 10 1 5 0 0 0 2 0 0 0 0 0 5 0 0 0 4 COG1551(Carbon storage regulator (could also regulate swarming and quorum sensing)) 18 16 15 9 2 2 3 6 1 1 3 0 6 4 11 6 1 0 5 6 4 4 12 7 2 3 13 3 1 2 3 3 2 0 11 12 19 139 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG15416() 85 1 0 1 3 0 1 2 1 0 4 1 2 10 2 2 2 2 0 3 0 2 1 2 0 8 3 0 2 2 4 10 0 2 0 2 2 181 10 2 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG4100(Cystathionine beta-lyase family protein involved in aluminum resistance) 33 11 0 24 5 8 1 2 0 2 0 0 0 0 0 0 0 0 0 5 19 14 31 30 24 0 7 5 19 14 23 9 1 2 14 0 0 21 32 0 0 0 0 0 0 0 0 0 0 0 0 5 0 2 0 0 NOG16663() 35 11 13 16 1 1 2 4 3 2 4 2 2 1 6 2 5 15 1 6 6 6 9 2 8 41 7 11 2 3 5 12 13 13 16 27 12 7 6 9 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 6 COG1243(Histone acetyltransferase) 3 11 17 12 2 6 3 2 15 5 5 0 7 16 13 9 9 17 2 20 6 3 16 4 10 17 2 1 3 2 0 0 5 4 7 31 51 18 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG11648(Uroporphyrinogen-Iii synthase) 5 8 8 6 13 2 13 4 3 1 9 2 6 7 0 4 4 6 5 2 7 8 4 8 0 5 6 9 8 0 1 13 18 10 57 35 8 9 16 15 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 6 NOG13634(Protein involved in DNA catabolism) 7 22 25 6 9 3 8 5 2 3 6 15 0 15 4 3 1 12 5 7 4 11 7 5 7 1 7 12 5 1 7 8 9 10 22 13 4 37 5 9 6 2 0 0 0 0 0 0 0 0 0 1 0 0 0 10 COG5477(Predicted small integral membrane protein) 17 29 13 18 0 1 10 8 6 1 2 9 3 6 1 7 1 11 3 13 6 3 10 11 7 4 13 15 3 0 5 14 16 16 19 19 4 6 2 10 3 2 0 0 0 0 0 0 0 0 0 3 0 0 0 11 COG3634(Alkyl hydroperoxide reductase, large subunit) 155 9 4 5 0 0 0 4 1 0 0 1 4 7 0 2 9 15 5 0 2 3 7 2 3 16 4 7 1 0 1 5 2 2 8 2 39 20 2 3 3 2 0 0 0 0 0 0 0 0 0 5 0 0 0 1 COG5361(Uncharacterized conserved protein) 151 1 1 2 1 0 1 16 2 1 4 5 3 13 7 4 5 7 13 3 2 0 2 2 1 1 3 0 3 1 0 43 5 4 4 9 6 16 10 3 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG06042(Double-Transmembrane region protein) 7 3 28 8 0 1 3 4 4 1 7 0 6 29 6 5 3 2 10 4 9 7 6 3 0 2 7 2 5 1 3 7 2 0 4 14 11 140 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2031(Short chain fatty acids transporter) 169 10 13 7 1 1 0 5 4 9 7 4 4 5 4 4 0 2 3 5 4 2 8 0 5 2 8 4 5 2 0 5 2 3 0 9 0 20 9 7 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG2920(Dissimilatory sulfite reductase (desulfoviridin), gamma subunit) 32 10 7 12 2 0 4 13 2 5 0 3 5 11 6 0 2 2 4 2 4 6 5 6 0 0 5 1 3 0 3 2 7 6 7 39 10 130 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5272(Ubiquitin) 2 7 18 6 17 23 3 26 17 5 3 3 16 11 4 3 6 6 12 25 4 3 7 1 3 12 3 3 2 24 3 12 16 5 2 8 7 11 2 2 4 4 0 0 0 0 0 0 0 0 0 4 0 0 0 4 NOG21162() 26 24 21 28 0 1 6 12 3 13 2 18 2 0 7 0 0 0 0 3 12 6 14 22 9 0 8 5 11 0 13 7 8 3 16 33 4 0 4 4 1 6 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG3734(2-keto-3-deoxy-galactonokinase) 63 16 5 8 2 7 1 9 3 2 3 0 13 18 5 3 2 3 16 3 6 2 7 1 7 0 4 2 5 2 5 11 11 16 25 16 2 17 5 15 6 2 0 0 0 0 0 0 0 0 0 6 0 0 0 3 NOG25988() 7 6 14 11 5 1 5 16 5 2 6 6 7 2 2 4 2 14 3 1 6 7 5 1 4 8 5 4 7 0 8 22 12 10 47 27 4 1 3 31 8 16 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1776(Chemotaxis protein CheC, inhibitor of MCP methylation) 136 26 16 10 0 6 1 0 2 5 2 0 0 7 2 1 12 5 3 2 4 1 8 9 4 4 9 10 6 1 7 3 0 0 4 5 24 11 3 2 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG09955() 3 6 6 8 17 1 11 4 11 1 2 2 3 2 4 5 10 4 6 8 2 10 9 5 3 1 0 4 4 0 2 11 16 10 48 35 3 34 7 17 6 6 0 0 0 0 0 0 0 0 0 4 0 0 0 7 COG4864(Uncharacterized protein conserved in bacteria) 4 14 51 5 0 3 3 5 1 4 2 1 6 6 8 4 3 5 3 7 13 10 27 8 6 6 7 4 6 2 5 7 8 8 7 15 3 58 2 12 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG26243() 6 3 5 11 4 11 4 8 1 0 2 2 3 20 2 4 11 5 12 7 3 9 4 2 3 29 4 6 1 6 5 14 13 8 16 11 1 85 2 4 5 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1864(DNA/RNA endonuclease G, NUC1) 18 10 10 5 0 1 6 1 2 3 7 0 2 13 6 2 12 15 7 6 4 7 10 5 4 53 9 0 3 1 3 23 15 12 20 24 5 14 3 6 6 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG5008(Tfp pilus assembly protein, ATPase PilU) 150 8 8 1 2 0 1 0 0 0 1 2 1 18 8 10 5 2 13 3 1 4 4 3 0 17 2 2 2 2 0 4 2 0 0 12 31 30 0 0 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG2898(Uncharacterized conserved protein) 200 4 13 0 0 0 0 2 2 1 2 0 0 2 2 0 5 12 1 0 2 0 0 1 0 12 4 0 2 0 2 3 0 2 2 3 5 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2978(Putative p-aminobenzoyl-glutamate transporter) 145 15 9 2 5 2 2 4 0 0 0 0 0 6 2 4 0 0 6 0 0 4 4 1 1 10 2 1 0 0 1 6 4 2 3 2 2 104 1 0 3 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 NOG04040() 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 27 34 4 0 0 0 0 0 0 109 2 0 0 0 0 0 0 0 0 0 0 175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1808(Predicted membrane protein) 38 1 7 4 14 5 4 4 1 3 2 0 1 7 2 4 0 0 5 6 7 3 5 0 2 1 1 1 6 2 6 23 5 9 37 10 6 85 30 4 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG14431() 3 5 9 4 7 2 12 4 9 3 9 7 2 0 8 3 0 10 1 9 8 4 11 8 1 0 8 12 3 3 5 14 17 10 68 20 1 6 8 19 5 4 0 0 0 0 0 2 0 0 0 5 0 0 0 6 COG3687(Predicted metal-dependent hydrolase) 252 9 24 7 0 0 0 7 2 5 0 0 0 3 0 1 0 1 4 2 3 0 2 1 0 4 5 1 2 0 2 1 0 0 2 2 2 6 1 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2837(Predicted iron-dependent peroxidase) 233 6 2 1 0 0 0 0 0 0 1 0 0 4 6 0 3 4 3 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 2 1 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08725() 13 17 19 29 3 9 5 7 1 1 2 0 8 16 6 2 0 2 8 12 10 8 22 20 12 3 5 4 8 3 9 5 13 16 26 8 3 3 4 7 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG18434() 1 3 7 4 2 3 4 44 5 1 6 5 9 3 3 6 8 6 4 16 4 2 3 7 12 33 7 3 1 12 3 6 8 18 6 31 4 14 11 2 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 21 COG2324(Predicted membrane protein) 2 4 18 1 0 0 0 3 5 7 0 1 0 0 1 1 21 26 2 1 4 3 6 0 4 80 4 1 2 1 0 6 6 2 7 8 7 103 3 6 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG3302(DMSO reductase anchor subunit) 20 10 2 8 2 8 5 10 4 9 3 5 9 24 0 3 6 7 8 5 4 2 6 7 8 18 8 2 4 0 4 10 15 13 29 18 3 14 5 16 7 3 0 0 0 0 0 0 0 0 0 1 0 0 0 8 NOG08817() 6 7 9 9 17 1 10 5 10 5 1 9 4 8 2 5 0 7 6 3 3 9 9 3 1 10 0 9 5 1 2 15 20 14 56 21 0 15 1 14 10 5 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG18589() 27 22 15 21 0 0 6 11 2 2 8 7 6 7 4 5 0 0 5 6 6 0 7 5 5 0 2 4 8 6 7 10 3 4 44 26 19 9 6 10 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG3931(Predicted N-formylglutamate amidohydrolase) 13 10 10 17 0 1 0 4 0 1 4 0 0 23 5 2 3 1 4 6 2 5 12 4 8 4 7 4 4 0 5 8 8 8 32 23 2 93 6 5 1 5 0 0 0 1 0 0 0 0 0 2 0 0 0 0 COG3208(Predicted thioesterase involved in non-ribosomal peptide biosynthesis) 306 1 9 1 1 0 0 0 0 0 0 0 0 4 2 0 0 0 0 0 1 0 3 1 0 1 1 2 0 5 2 1 0 0 0 1 0 7 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4258(Predicted exporter) 176 5 13 7 1 0 1 2 0 0 0 10 4 1 8 11 4 2 0 2 10 3 14 4 2 2 0 0 4 0 1 1 2 0 14 16 5 23 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04720() 12 8 9 1 4 5 8 7 3 2 0 3 14 2 6 5 2 3 6 11 5 1 5 8 5 10 9 0 0 8 1 11 9 6 38 11 2 75 17 8 7 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG2912(Uncharacterized conserved protein) 133 2 9 6 2 5 1 3 1 0 2 0 2 15 9 4 16 14 11 1 2 6 1 1 0 21 1 0 1 0 2 2 2 3 0 13 4 49 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4956(Integral membrane protein (PIN domain superfamily)) 29 8 10 19 5 3 1 0 0 0 1 0 0 2 0 0 2 0 1 8 15 6 32 12 27 2 1 8 17 8 16 16 4 1 4 2 8 53 22 2 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 COG2969(Stringent starvation protein B) 78 2 6 0 1 1 0 5 4 1 11 3 2 21 8 5 17 12 12 1 0 3 0 3 2 6 5 0 0 0 3 3 1 1 13 17 6 92 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11598() 7 11 13 6 0 1 6 0 3 4 1 3 0 5 6 5 3 11 6 3 2 5 7 3 8 9 4 6 6 0 2 12 7 0 28 21 17 90 3 16 5 1 0 0 2 0 0 0 0 0 0 0 0 0 0 3 NOG20787(Cytochrome c protein) 19 20 17 22 1 6 17 21 9 8 2 20 11 7 7 9 15 18 9 8 9 14 25 5 5 0 7 9 6 1 4 0 2 0 8 4 3 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35984(Surface protein) 2 2 0 1 4 7 1 7 1 1 7 8 10 5 0 4 11 14 6 11 0 8 7 6 6 51 4 0 2 6 0 25 34 16 4 16 8 28 12 4 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG5007(Predicted transcriptional regulator, BolA superfamily) 88 13 26 10 1 0 1 4 4 1 4 1 6 11 8 5 11 8 5 3 7 1 7 8 1 7 4 0 2 0 1 2 1 2 0 10 7 73 0 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1657(Squalene cyclase) 180 2 13 6 0 3 0 2 1 0 0 0 0 6 0 0 0 2 5 3 4 0 3 0 2 8 0 5 0 3 2 5 1 2 0 11 7 61 4 4 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0645(Predicted kinase) 116 0 2 1 0 1 1 2 0 1 0 0 2 2 0 0 1 2 1 1 2 0 0 0 0 1 2 2 1 1 0 0 0 0 0 0 25 182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09624() 19 15 15 15 1 9 7 6 4 5 2 2 1 6 4 1 0 0 1 4 1 12 15 6 5 0 9 9 6 1 10 8 7 2 20 32 11 33 9 23 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 8 NOG23336() 139 3 0 2 6 1 0 0 1 0 0 0 3 6 0 0 0 2 2 0 0 0 0 1 0 4 0 0 0 3 0 1 0 0 0 0 8 167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3135(Uncharacterized protein involved in benzoate metabolism) 194 16 6 6 1 5 3 1 5 0 3 5 0 7 2 2 6 2 5 6 4 6 4 1 1 18 0 4 5 1 2 4 0 2 4 2 2 6 1 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG20593() 1 1 7 4 2 0 1 45 15 3 5 11 21 9 4 9 19 11 13 25 2 5 3 3 11 14 1 2 0 0 0 7 5 6 0 9 17 48 2 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3028(Uncharacterized protein conserved in bacteria) 69 7 3 5 1 0 1 2 0 3 14 5 2 18 6 7 13 14 5 2 0 0 5 0 3 14 5 0 0 2 5 2 5 0 4 4 21 95 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG24934() 30 8 1 18 6 9 1 0 0 1 0 0 0 0 0 0 0 0 4 0 14 5 37 13 25 0 2 2 15 17 34 15 7 2 6 2 0 35 20 2 3 4 0 0 0 0 0 0 0 0 0 9 0 0 0 0 NOG39440() 12 20 8 18 0 2 10 15 2 2 0 6 2 0 4 13 17 10 1 5 3 8 7 2 8 22 0 4 7 0 5 9 6 6 23 51 2 0 10 6 4 3 0 0 1 0 0 0 0 0 0 3 0 1 0 9 NOG08480(Phycocyanobilin:Ferredoxin oxidoreductase) 18 4 1 9 3 3 1 4 0 4 2 0 2 0 0 0 0 0 0 1 21 10 36 14 33 2 6 9 11 12 13 14 15 5 12 8 0 36 18 10 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2339(Predicted membrane protein) 7 25 18 15 0 2 3 5 1 1 4 1 3 8 7 3 14 2 7 5 5 6 17 8 16 11 5 6 4 1 2 13 11 7 22 32 8 10 6 10 4 4 0 1 0 0 0 0 0 0 0 3 0 0 0 3 NOG11613() 9 19 27 18 1 1 3 5 3 3 6 5 6 14 3 1 2 1 5 7 5 9 16 10 11 0 8 4 5 0 2 13 14 7 16 34 2 10 9 13 1 7 0 0 0 0 0 0 0 0 2 2 0 0 0 7 COG3812(Uncharacterized protein conserved in bacteria) 145 18 10 4 1 1 0 2 3 3 8 2 4 2 0 2 6 2 8 2 3 0 5 4 3 7 2 7 3 4 0 10 12 2 23 5 5 5 7 8 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG1697(DNA topoisomerase VI, subunit A) 1 9 27 10 2 1 0 0 0 0 0 0 1 10 2 4 0 2 3 3 7 22 20 13 3 14 15 10 3 1 2 14 21 2 0 19 22 14 2 17 18 8 0 0 0 0 2 0 0 0 0 4 0 0 0 16 NOG39441() 4 5 75 7 0 2 2 4 4 0 8 3 5 4 0 2 2 1 7 3 9 12 18 11 5 2 10 8 5 2 9 7 15 2 2 19 6 31 5 15 0 6 0 0 0 1 0 0 0 0 0 5 0 0 0 0 NOG25752() 3 4 14 15 2 3 4 4 3 0 18 8 2 45 14 7 2 12 20 7 1 13 7 8 12 3 2 3 4 2 4 6 1 0 12 8 8 48 4 3 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG2066(Glutaminase) 102 18 17 23 3 1 3 1 1 1 0 3 0 6 0 1 4 11 3 2 3 4 16 3 12 0 2 0 4 9 2 0 2 6 6 1 7 61 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG14014() 1 2 3 3 1 1 1 17 4 17 5 3 6 0 0 1 0 0 14 0 5 1 15 3 9 1 6 10 13 12 3 5 7 0 8 0 2 142 1 2 5 6 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG4852(Predicted membrane protein) 21 19 6 17 3 0 5 3 4 0 0 0 6 5 2 0 11 11 4 7 6 6 9 8 14 3 6 4 4 2 6 9 9 0 14 37 3 43 6 10 4 10 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG09480() 19 10 0 8 0 5 1 0 0 5 0 0 0 0 0 0 0 0 1 3 26 8 28 21 38 15 4 6 19 15 13 19 3 4 8 2 0 39 15 3 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG3025(Uncharacterized conserved protein) 118 4 3 0 0 0 0 0 0 0 1 2 0 0 0 0 3 2 0 0 0 0 0 3 1 3 1 0 0 0 2 1 0 0 0 0 23 174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3249(Uncharacterized protein conserved in bacteria) 65 6 6 1 0 2 3 6 2 0 8 1 3 8 4 3 0 0 8 2 7 3 2 3 2 0 3 3 3 1 4 4 3 0 10 14 6 138 0 2 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG11085() 8 15 13 13 2 0 2 8 8 7 1 7 2 14 2 0 2 0 10 5 5 8 12 7 8 1 12 11 9 5 8 15 14 13 35 15 1 11 7 10 5 3 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG5306(Uncharacterized conserved protein) 184 2 7 1 0 2 1 4 0 2 3 1 0 6 4 0 0 2 11 3 0 0 0 0 1 0 4 0 2 0 2 5 3 0 4 3 34 44 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG09811() 6 0 0 1 0 0 1 45 5 5 2 2 8 9 4 5 4 5 10 1 4 2 14 5 10 53 5 11 19 12 6 8 9 9 6 7 0 28 2 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 2 9 NOG21239(Possible multidrug efflux transporter, MFS protein) 25 8 0 13 5 1 1 0 0 2 0 0 0 0 0 0 6 4 2 6 29 12 24 17 22 7 0 4 12 30 34 15 4 0 3 2 0 17 25 2 0 2 0 0 0 0 0 0 0 0 0 3 0 0 2 1 NOG11654() 3 6 9 3 2 2 10 5 16 3 9 4 5 7 2 0 0 6 5 1 5 14 10 3 9 0 7 8 3 0 4 13 19 12 51 32 3 5 10 22 2 3 0 0 0 0 0 0 1 0 0 2 0 0 0 4 COG2045(Phosphosulfolactate phosphohydrolase and related enzymes) 22 11 6 19 4 3 3 1 4 0 1 1 2 0 4 0 2 3 1 2 13 9 31 11 20 8 3 2 9 13 12 17 3 2 3 12 2 48 26 3 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 NOG04002(Alfa-L-Rhamnosidase) 0 4 2 4 7 6 2 15 8 4 4 3 5 19 0 3 3 10 8 8 3 6 10 7 4 7 8 8 1 11 0 9 11 13 20 18 13 39 1 22 3 2 0 0 0 0 0 0 0 0 0 5 0 0 0 3 COG2974(DNA recombination-dependent growth factor C) 96 22 12 15 1 0 4 8 2 5 0 2 5 11 4 1 2 3 4 1 6 2 7 1 3 1 4 6 0 0 0 18 11 5 14 16 6 17 5 4 6 6 0 0 0 0 0 0 0 0 0 0 0 1 0 1 COG2414(Aldehyde:ferredoxin oxidoreductase) 7 11 25 17 0 1 0 7 0 4 1 0 5 21 0 10 11 7 6 6 6 12 21 12 9 7 13 16 5 1 4 5 6 2 0 6 16 34 0 3 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 18 NOG04755(Protein involved in lipopolysaccharide biosynthesis) 24 12 1 16 3 4 3 0 0 0 0 0 0 0 0 0 0 0 0 4 25 12 24 27 13 0 6 12 20 19 10 19 3 0 5 2 0 40 27 0 0 0 0 0 0 0 0 0 2 0 0 4 0 0 0 0 COG0068(Hydrogenase maturation factor) 105 6 2 0 2 0 0 0 0 0 0 0 0 2 0 1 3 7 1 0 0 1 1 1 0 6 0 0 2 0 0 0 0 0 0 2 18 177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3970(Fumarylacetoacetate (FAA) hydrolase family protein) 61 8 13 18 3 8 4 3 2 0 3 0 0 1 0 8 6 12 8 2 7 8 11 5 3 30 5 9 3 1 4 15 7 4 16 3 2 24 1 2 5 3 0 0 0 0 0 0 0 0 0 0 0 0 2 6 NOG06545() 196 0 1 0 0 0 0 3 1 2 9 2 0 2 0 1 4 11 8 0 0 1 0 0 1 51 8 3 1 3 0 2 1 0 4 4 6 2 0 3 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG17496() 2 14 24 8 10 3 10 0 5 0 3 2 2 5 5 4 2 2 3 3 9 10 9 5 4 0 4 9 3 0 6 16 15 8 27 30 12 9 5 25 9 7 0 0 0 0 0 0 0 0 0 3 0 1 0 3 NOG08033() 5 2 19 4 8 0 4 17 5 7 1 5 11 0 0 0 2 6 12 8 2 4 7 1 8 6 15 7 7 2 0 16 7 14 16 25 2 39 5 25 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG3952(Predicted membrane protein) 12 10 18 19 2 3 3 3 0 1 3 3 1 7 4 1 1 3 4 6 11 2 12 3 10 26 8 5 4 0 4 12 15 4 10 21 10 48 2 10 1 3 0 0 0 0 0 0 0 0 2 4 0 0 0 4 COG2968(Uncharacterized conserved protein) 87 6 17 6 0 0 1 4 1 0 4 0 0 2 2 0 23 31 2 5 0 5 2 1 0 76 2 0 1 1 0 1 0 0 4 1 16 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19293() 0 0 3 1 1 5 2 6 6 6 2 13 5 4 8 2 2 2 4 7 0 0 4 4 0 0 9 9 1 2 2 15 12 12 26 29 2 95 5 14 8 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG13352() 19 33 67 24 2 1 2 0 0 0 0 0 0 7 4 1 0 0 2 6 11 9 26 10 23 0 7 4 3 0 0 2 2 4 2 3 2 37 1 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 17 COG3330(Uncharacterized protein conserved in bacteria) 29 4 2 23 2 4 2 0 0 0 0 0 3 0 0 0 0 0 4 1 8 10 21 20 14 2 7 7 10 16 22 11 2 5 6 1 2 55 31 2 2 2 0 0 0 0 2 0 0 0 0 2 0 0 0 0 NOG11824() 39 6 3 4 1 5 2 3 0 6 3 1 0 6 4 1 5 3 2 7 1 4 4 2 0 5 11 1 2 0 3 11 12 9 14 13 4 113 5 15 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG26066() 10 6 5 17 0 5 4 11 0 3 5 0 2 29 5 2 5 10 9 5 8 5 6 8 3 8 5 7 2 7 1 8 6 6 6 22 4 75 6 0 1 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG3882(Predicted enzyme involved in methoxymalonyl-ACP biosynthesis) 7 16 33 16 1 1 5 4 3 0 8 3 7 3 4 3 2 10 4 8 2 6 10 1 5 10 6 4 8 2 8 7 6 12 13 35 26 12 6 6 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG13499() 11 22 25 12 2 0 2 14 2 12 4 7 5 12 3 7 1 0 12 5 9 3 1 1 3 0 9 10 3 2 3 20 18 13 27 23 8 0 3 10 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG10098() 58 11 14 8 2 1 3 7 2 1 3 0 2 6 2 1 7 6 0 11 6 2 7 7 5 19 5 11 6 1 0 13 8 8 8 28 7 19 0 5 4 8 0 0 0 0 0 0 0 0 0 2 0 1 1 6 NOG29289() 7 6 10 6 2 2 4 9 1 0 8 2 7 29 2 3 5 11 9 7 3 14 8 2 4 14 9 8 6 1 3 8 4 3 33 13 3 32 3 15 2 6 0 0 0 0 0 0 0 0 0 3 0 0 0 5 COG1865(Uncharacterized conserved protein) 15 12 10 11 1 0 3 3 5 5 5 0 1 13 2 0 2 0 2 6 6 1 6 4 2 23 2 4 1 0 2 18 11 3 13 16 2 112 2 2 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG19887() 29 9 15 7 4 3 2 0 0 2 1 2 0 0 2 2 4 0 1 3 3 2 7 4 9 0 8 7 8 5 9 30 9 7 24 18 2 25 26 14 5 4 0 0 0 0 0 0 0 0 0 8 0 0 2 9 NOG22299() 0 5 22 9 6 0 8 2 10 1 2 8 2 2 4 3 3 5 5 9 1 3 9 7 9 0 15 2 5 0 1 15 15 8 47 32 5 11 4 14 7 4 0 0 0 0 0 0 0 0 0 8 0 0 0 2 NOG06102() 6 26 65 19 3 0 4 8 4 2 4 3 2 8 4 0 1 0 0 2 8 10 8 2 2 9 1 9 4 0 1 17 13 5 27 4 3 19 10 10 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 COG2993(Cbb3-type cytochrome oxidase, cytochrome c subunit) 44 1 2 2 2 2 0 0 0 0 0 2 0 14 5 1 7 15 5 0 0 4 1 2 2 19 5 0 0 0 0 1 0 1 0 2 23 164 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG1867(N2,N2-dimethylguanosine tRNA methyltransferase) 11 6 23 6 3 1 0 0 0 0 0 0 0 3 7 0 2 0 2 6 4 7 13 6 0 5 2 5 3 7 5 10 12 13 15 21 7 62 23 11 9 2 0 0 0 0 0 0 0 0 0 9 0 0 0 8 COG1275(Tellurite resistance protein and related permeases) 128 0 0 0 1 1 0 2 0 0 0 0 0 2 0 0 1 1 1 0 2 0 0 0 0 1 0 0 0 0 1 0 0 2 0 1 12 173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25534() 3 7 7 9 5 1 8 11 7 0 0 3 2 6 12 6 5 2 4 12 3 4 17 6 13 2 1 10 5 0 4 18 13 7 34 17 0 11 10 22 7 6 0 0 0 0 0 0 0 0 0 1 0 0 0 8 NOG06330() 6 10 3 6 0 8 6 7 2 11 2 0 0 3 2 1 7 18 6 4 6 6 12 5 2 19 7 7 5 0 5 16 8 5 22 7 18 33 9 12 3 9 0 0 0 0 0 0 0 0 0 2 0 0 0 9 COG3214(Uncharacterized protein conserved in bacteria) 122 0 8 4 4 1 3 1 0 0 4 0 0 9 4 4 7 9 3 6 2 4 4 4 2 65 8 0 4 0 0 0 3 0 0 10 3 20 1 2 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2706(3-carboxymuconate cyclase) 147 5 11 10 1 7 1 4 0 4 0 0 2 5 2 2 7 3 10 0 2 3 13 0 1 15 8 4 4 3 3 1 4 2 6 9 0 25 1 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 NOG23061(Site-Specific recombinase, phage) 2 16 3 1 2 3 2 10 1 2 9 0 6 36 3 3 7 16 11 5 6 3 3 4 7 23 2 6 1 12 9 3 1 2 3 2 6 68 10 0 3 0 0 0 0 0 0 0 0 0 0 3 0 0 0 12 NOG08368() 0 8 15 3 0 0 0 0 0 0 0 0 0 3 0 1 22 21 1 11 7 10 5 8 3 95 5 9 2 6 2 8 12 1 10 29 0 0 0 12 7 5 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG4945(Membrane-anchored protein predicted to be involved in regulation of amylopullulanase) 3 2 3 6 0 0 1 0 0 0 0 0 0 13 0 9 15 2 1 6 4 12 8 14 7 0 30 19 9 0 5 21 15 12 18 19 0 2 12 5 13 15 0 2 0 0 0 0 0 0 0 9 0 0 0 14 COG3744(Uncharacterized protein conserved in bacteria) 113 1 2 1 0 4 0 0 0 0 0 0 1 6 0 1 1 2 6 1 0 0 3 0 4 5 1 2 0 0 0 1 0 0 0 2 6 161 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5458(Uncharacterized conserved protein) 10 5 13 8 1 4 3 10 2 0 0 0 0 13 0 0 0 0 6 10 5 2 8 2 8 3 12 2 3 0 3 15 12 5 17 23 4 65 9 10 4 12 0 0 2 0 0 0 0 0 0 4 0 0 2 9 COG3034(Uncharacterized protein conserved in bacteria) 48 10 14 10 0 2 0 1 5 3 2 1 2 7 5 2 8 3 5 8 1 4 11 8 15 10 5 4 5 1 2 10 11 5 14 25 17 16 5 9 1 2 0 0 0 0 0 1 0 0 0 0 0 0 0 7 COG0121(Predicted glutamine amidotransferase) 175 6 3 3 1 0 1 0 4 0 0 0 0 2 2 1 18 19 1 0 0 2 3 2 0 33 3 2 0 1 0 2 1 0 0 3 25 6 1 1 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG2223(Nitrate/nitrite transporter) 91 8 7 4 3 2 3 0 0 0 1 0 0 6 0 0 11 13 4 3 20 4 13 11 6 6 6 2 3 3 0 3 0 4 4 6 9 45 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1464(ABC-type metal ion transport system, periplasmic component/surface antigen) 310 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 2 1 0 1 0 0 0 1 0 1 0 0 1 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08132() 224 20 4 0 1 0 1 0 1 2 0 0 0 2 0 0 0 0 1 4 0 0 0 2 1 2 2 0 1 3 0 0 0 0 0 4 8 40 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17113(Major tail protein) 32 6 14 8 0 0 0 9 2 0 5 0 2 1 0 1 2 2 3 8 8 15 18 9 15 31 0 9 8 21 4 4 4 0 6 9 0 2 27 4 8 2 0 0 0 0 0 0 0 0 0 2 0 0 0 23 NOG37189() 18 5 3 33 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 6 34 24 20 0 11 4 12 25 22 17 3 2 10 1 0 31 17 2 0 2 0 0 0 0 0 0 0 0 0 7 0 0 0 1 NOG05969(Glutamate-Cysteine ligase) 60 13 12 6 0 0 0 2 0 3 0 3 4 6 6 7 22 19 5 6 2 0 14 5 7 9 0 4 2 0 3 8 7 10 7 15 16 2 4 8 7 4 0 0 0 0 0 0 0 0 0 3 0 0 0 12 NOG04736() 26 5 3 13 1 3 3 0 0 2 0 0 0 0 0 0 0 0 0 7 32 7 28 21 9 0 5 5 20 22 22 13 3 6 4 3 0 36 23 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG06237() 13 10 17 6 1 1 5 4 1 4 0 0 4 6 0 1 2 2 4 11 0 14 7 4 3 1 12 10 12 2 4 18 19 14 32 30 0 2 7 14 4 10 0 0 0 0 0 0 0 0 0 6 0 0 0 6 NOG04734() 24 3 11 13 2 6 1 0 0 0 0 0 2 0 0 0 0 0 0 2 20 11 35 17 16 4 3 5 19 30 18 7 1 4 8 0 0 35 17 2 0 0 0 0 0 0 0 0 0 0 0 6 0 1 0 0 COG4928(Predicted P-loop ATPase) 234 13 11 8 0 0 0 0 0 0 0 3 0 2 0 1 0 0 0 0 1 0 5 0 3 1 0 1 0 1 0 5 5 4 11 4 3 0 1 4 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 NOG09490() 7 20 19 16 2 1 16 8 0 9 3 0 0 24 4 6 2 1 6 7 5 6 9 7 5 2 11 4 2 1 0 4 7 3 11 20 3 46 7 6 3 2 0 0 0 0 0 0 0 0 0 4 0 0 0 3 COG4731(Uncharacterized protein conserved in bacteria) 54 21 22 13 6 0 3 6 6 2 2 1 1 4 2 3 5 1 6 6 10 6 7 6 1 5 4 2 3 2 0 6 9 7 19 11 3 25 6 10 2 6 0 1 0 0 0 0 0 0 0 2 0 0 0 5 COG2104(Sulfur transfer protein involved in thiamine biosynthesis) 15 7 2 12 0 4 2 1 0 3 2 2 1 8 5 1 3 8 4 5 8 8 9 9 5 4 8 12 10 10 5 7 6 2 6 17 5 89 7 1 1 1 0 0 0 0 1 0 0 0 0 1 0 0 0 4 NOG06497(Saccharopine dehydrogenase) 4 2 5 3 4 0 5 1 6 0 12 0 5 10 1 3 2 3 10 5 9 3 7 6 7 1 6 11 1 0 5 21 18 4 27 24 11 20 11 31 6 4 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG08890() 317 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4409(Neuraminidase (sialidase)) 1 9 13 7 9 11 4 4 0 3 5 0 6 3 4 1 9 6 8 0 2 5 2 4 1 9 3 3 3 11 2 18 12 8 56 23 6 26 3 9 2 4 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG14461(DNA repair protein RecO) 1 9 6 5 10 1 8 11 5 1 7 7 3 10 2 2 2 6 1 7 3 8 8 4 6 0 4 4 4 1 6 12 12 10 36 28 3 5 6 39 9 3 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG19951() 10 6 4 8 1 4 1 5 4 1 5 0 4 11 3 5 3 0 5 4 8 4 17 10 12 0 9 6 4 1 8 15 12 10 13 7 1 68 3 11 6 6 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG3843(Type IV secretory pathway, VirD2 components (relaxase)) 288 0 1 0 0 0 1 0 0 0 0 0 0 3 0 2 1 0 0 0 0 0 0 0 3 0 6 0 0 0 1 0 0 0 0 2 0 11 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3165(Uncharacterized protein conserved in bacteria) 92 11 7 2 2 0 1 1 2 2 5 1 8 3 3 3 12 5 3 1 5 1 0 1 3 2 1 3 0 1 2 4 1 2 3 11 15 93 4 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17638() 0 5 21 3 7 0 3 9 14 8 5 2 5 4 8 5 2 4 21 4 6 9 5 5 9 13 2 10 9 1 3 8 11 6 4 25 8 17 4 9 5 4 0 0 0 0 0 0 0 0 0 10 0 0 0 7 NOG10856() 1 3 4 4 1 0 0 1 0 4 3 0 0 7 0 5 8 3 5 2 1 1 1 1 0 27 0 3 0 0 0 2 5 8 17 8 2 167 3 14 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 COG3007(Uncharacterized paraquat-inducible protein B) 112 4 4 13 4 3 2 7 2 1 5 0 8 11 4 2 3 0 18 4 3 6 5 3 0 14 5 0 0 1 1 3 7 0 10 8 12 19 5 1 0 7 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3071(Uncharacterized enzyme of heme biosynthesis) 121 15 28 13 0 1 0 3 4 0 12 1 2 20 6 2 3 2 2 2 4 1 4 1 0 3 1 1 0 0 4 0 2 0 8 13 17 18 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG17523(HNH endonuclease family) 12 5 11 8 2 3 3 4 0 0 0 0 2 1 2 3 0 1 1 5 20 7 20 8 30 25 3 6 11 13 9 5 1 0 1 5 4 70 5 1 2 2 0 2 0 0 0 0 0 0 0 1 0 0 0 3 COG3133(Outer membrane lipoprotein) 60 15 20 4 0 1 1 1 1 2 2 2 2 9 1 1 8 2 5 5 5 3 6 2 2 0 1 5 5 0 2 3 7 0 27 10 6 80 2 2 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1938(Archaeal enzymes of ATP-grasp superfamily) 1 15 20 5 0 0 0 0 0 0 0 3 2 8 6 1 0 2 0 10 10 13 28 5 7 27 5 6 9 3 5 18 7 8 2 11 11 0 8 14 7 7 0 0 0 0 0 0 0 0 0 5 0 0 0 27 COG5310(Homospermidine synthase) 1 1 0 0 0 0 1 0 0 0 0 2 2 0 0 0 23 31 5 0 0 0 0 0 0 209 2 0 0 0 0 0 0 0 0 2 6 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3926(Putative secretion activating protein) 6 7 4 6 1 3 5 16 1 4 5 1 4 13 0 0 5 2 6 5 3 4 10 12 4 10 5 6 5 6 3 6 11 3 8 6 6 94 2 4 1 2 0 0 0 0 0 0 0 0 0 5 0 0 0 6 NOG11102() 0 0 0 1 0 0 1 4 0 10 0 0 4 0 0 1 0 0 12 0 0 4 1 0 5 2 1 2 3 3 4 4 7 1 2 0 0 231 0 0 2 6 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG3781(Predicted membrane protein) 183 7 7 5 4 2 0 0 1 3 1 0 0 9 0 0 0 5 2 1 4 1 6 1 2 2 1 1 1 6 2 5 3 2 0 2 3 35 0 2 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5164(Transcription elongation factor) 3 8 11 9 7 1 0 20 2 14 6 1 8 6 0 1 7 2 2 4 7 2 14 7 3 20 8 7 15 3 5 3 7 6 6 25 2 25 10 15 2 4 0 0 0 2 0 0 0 0 0 1 0 0 0 4 COG4372(Uncharacterized protein conserved in bacteria with the myosin-like domain) 17 12 2 19 2 5 0 2 0 0 0 0 0 0 0 0 0 0 2 3 25 8 21 12 11 0 10 5 16 27 9 15 6 4 4 1 0 42 20 7 1 2 0 0 2 0 0 0 0 0 0 1 0 0 0 1 NOG11638(Signal peptidase) 7 9 8 8 13 2 4 11 7 2 5 7 6 9 2 2 4 10 9 2 1 5 7 2 0 1 1 8 2 1 1 9 9 11 56 33 0 8 1 13 7 6 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG17045(Cytochrome subunit of sulfide) 7 10 12 8 0 1 0 5 1 2 4 0 0 7 0 3 6 2 1 12 6 1 5 5 10 1 5 3 3 0 4 13 6 10 20 14 3 101 3 8 4 4 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG1481(Uncharacterized protein conserved in bacteria) 0 2 1 0 0 0 0 0 0 0 0 0 0 4 0 0 34 26 3 0 0 0 0 1 0 81 1 2 0 0 0 1 0 0 4 2 0 151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22842() 5 3 1 1 1 0 0 19 0 2 40 5 2 2 0 0 0 0 9 0 1 0 0 1 4 2 9 4 3 0 0 12 3 2 5 0 0 171 3 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26077() 1 2 8 5 7 1 9 13 9 5 0 6 4 7 4 1 2 5 3 2 1 2 10 3 1 2 6 6 0 1 1 32 9 16 45 30 4 1 13 22 8 5 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16525() 15 4 15 10 0 0 7 0 0 0 0 5 0 9 8 7 2 0 6 8 8 6 10 3 7 8 12 11 12 0 2 10 20 15 10 23 3 5 4 4 16 5 0 0 0 0 0 0 0 0 0 5 0 0 2 17 COG3172(Predicted ATPase/kinase involved in NAD metabolism) 16 7 9 9 7 1 4 5 2 0 12 3 2 2 4 2 8 4 3 3 7 14 6 3 2 11 7 4 3 1 3 13 13 7 18 21 0 41 7 11 4 8 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG1647(Esterase/lipase) 56 1 3 2 0 0 0 0 0 0 0 0 2 0 0 1 19 34 1 0 4 1 3 0 4 123 2 1 0 1 0 3 1 0 0 0 7 35 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2719(Uncharacterized conserved protein) 145 6 2 2 1 0 4 1 3 4 0 1 0 5 4 0 4 1 0 0 0 0 11 6 1 18 2 0 8 3 4 7 0 0 0 9 17 32 0 5 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG3495(Uncharacterized protein conserved in bacteria) 16 18 9 8 2 6 2 6 1 8 5 4 2 16 6 0 2 0 2 2 5 9 18 10 2 3 5 6 3 1 5 2 1 2 6 12 9 86 3 3 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG18857() 58 10 4 6 2 7 1 6 3 0 0 5 0 15 0 4 4 2 2 5 3 3 5 7 5 4 5 13 6 3 4 17 9 5 26 8 6 8 11 15 3 3 0 0 0 0 0 0 0 0 0 7 0 0 1 2 COG3236(Uncharacterized protein conserved in bacteria) 8 2 9 2 6 0 2 2 12 0 5 4 2 6 2 5 6 8 1 11 1 7 3 3 4 24 12 7 0 1 2 10 13 4 19 16 12 40 11 9 8 3 0 0 0 0 0 0 0 0 0 0 0 0 0 11 COG3026(Negative regulator of sigma E activity) 84 2 5 1 0 1 0 3 3 0 6 6 3 11 0 9 17 3 9 0 0 0 1 1 1 12 1 0 0 0 0 0 0 0 0 2 2 127 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG08710() 13 12 8 7 1 0 6 10 3 6 2 9 2 1 8 0 1 0 1 3 2 10 6 13 5 2 12 9 22 0 11 5 12 4 29 22 2 13 2 4 3 12 0 2 0 0 0 0 0 0 0 8 0 0 0 9 NOG10877() 2 6 13 9 1 1 2 6 6 1 4 7 4 9 2 7 8 5 10 4 1 1 6 5 3 17 3 5 4 2 2 19 10 7 17 23 5 41 5 18 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG30027() 309 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2110(Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1) 67 14 28 9 2 2 1 0 0 0 4 1 2 8 4 2 6 4 6 6 14 7 16 6 9 3 6 0 6 3 2 4 3 2 2 18 7 14 5 5 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG26855() 4 10 10 6 2 2 5 1 1 0 3 3 0 4 0 4 0 4 0 3 6 5 8 5 6 33 12 4 2 0 5 17 13 9 35 18 3 5 14 18 11 5 0 0 0 0 0 0 0 0 0 3 0 0 0 10 COG1442(Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases) 28 4 11 6 2 4 2 7 1 0 0 3 0 1 11 10 4 4 4 7 2 3 7 6 4 7 9 18 10 4 10 6 6 9 7 24 2 46 1 4 7 0 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG2143(Thioredoxin-related protein) 1 3 0 4 0 0 2 6 4 11 3 8 0 19 1 0 5 1 6 4 5 0 0 2 1 1 3 3 2 2 2 5 5 5 24 5 11 129 6 6 4 2 0 0 0 0 0 0 0 2 0 0 0 0 0 6 COG1514(2-5 RNA ligase) 76 18 36 7 0 0 0 1 0 2 0 0 1 0 0 0 0 2 0 2 2 3 4 3 2 20 2 2 3 0 2 5 1 0 2 5 24 80 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 COG2520(Predicted methyltransferase) 0 8 14 4 1 0 0 0 0 4 0 1 0 5 4 1 0 1 1 11 3 20 18 8 3 9 5 9 11 8 5 16 23 11 2 11 26 1 4 9 12 15 0 0 0 0 0 0 0 0 0 3 0 0 0 22 COG3964(Predicted amidohydrolase) 21 14 43 24 0 4 1 5 4 9 4 2 4 8 4 1 4 4 3 12 2 9 5 4 3 12 0 3 0 0 4 2 9 3 21 13 0 28 4 7 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG1027(Aspartate ammonia-lyase) 68 7 15 8 2 0 0 0 0 0 1 9 0 5 5 0 6 4 8 5 1 2 3 0 3 14 1 0 0 1 2 1 0 0 2 8 15 112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5387(Chaperone required for the assembly of the mitochondrial F1-ATPase) 5 5 5 18 0 1 2 10 4 4 7 4 1 8 0 5 0 1 10 5 2 5 6 5 5 1 8 5 2 0 3 14 11 9 29 16 2 54 10 7 0 6 0 0 0 0 0 0 0 0 0 3 0 0 0 10 NOG10846() 24 7 2 16 7 9 4 0 0 0 0 0 3 0 0 0 0 0 0 1 25 4 18 17 16 0 0 4 10 20 20 12 2 2 6 2 0 41 27 1 1 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG21340() 10 12 1 3 1 4 10 21 9 11 3 19 3 2 7 6 8 7 9 1 2 0 1 1 2 12 0 0 1 0 0 7 6 4 14 17 2 76 1 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 COG3381(Uncharacterized component of anaerobic dehydrogenases) 115 1 10 2 1 3 2 0 0 1 1 0 0 1 2 1 7 2 5 2 3 3 5 3 4 4 5 2 1 0 3 2 1 4 6 5 4 85 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG06494() 9 10 17 10 0 0 1 0 1 0 2 0 3 21 0 0 1 0 8 12 0 4 15 10 9 2 7 11 7 0 2 4 6 15 25 13 1 37 9 13 2 6 0 0 0 0 0 0 0 0 0 3 0 0 0 10 NOG07857() 52 15 23 10 7 1 4 2 1 0 2 1 0 4 0 2 1 4 1 8 4 5 11 4 15 1 6 6 6 1 3 12 7 8 27 5 2 10 8 11 0 4 0 0 0 0 0 0 0 0 0 3 0 0 0 9 COG4654(Cytochrome c551/c552) 132 0 1 1 0 0 1 3 5 8 11 2 4 12 2 5 24 24 3 0 0 1 1 1 1 17 1 3 0 2 0 5 1 0 2 5 2 25 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09722() 39 3 40 11 2 2 2 11 2 4 0 1 0 2 2 3 2 4 1 8 8 7 10 4 5 8 4 9 8 0 2 9 5 2 6 29 3 10 6 11 0 7 0 0 0 0 0 0 0 0 0 6 0 0 0 8 COG1264(Phosphotransferase system IIB components) 293 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19097() 2 7 8 4 13 1 4 4 4 7 7 0 2 1 2 1 1 8 6 4 1 13 14 4 7 4 1 6 6 1 2 14 14 2 30 24 8 28 8 13 6 6 0 0 0 0 0 0 0 0 2 2 0 0 0 4 COG5309(Exo-beta-1,3-glucanase) 1 0 0 0 1 1 4 20 12 13 10 5 5 13 24 9 3 4 16 7 0 2 1 3 2 2 14 2 0 1 0 15 10 0 42 14 5 19 4 12 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13286() 69 7 4 7 1 2 3 1 1 0 3 3 4 12 6 2 9 3 7 6 4 4 5 0 4 3 5 5 3 1 3 6 4 10 23 13 2 15 8 15 5 2 0 0 0 0 0 0 0 0 0 4 0 0 0 11 NOG26810() 1 5 32 2 5 0 5 4 4 2 4 5 0 0 4 0 0 4 6 4 7 10 11 3 2 2 2 5 4 2 0 28 23 6 32 24 3 2 4 24 8 9 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG04722(Apocytochrome f protein) 22 5 5 24 3 6 1 0 0 0 0 0 0 0 0 1 0 0 1 1 32 17 19 16 16 0 2 5 11 15 16 15 1 3 10 5 1 25 13 5 1 2 0 0 0 0 0 0 0 2 0 1 0 0 0 3 COG5533(Ubiquitin C-terminal hydrolase) 3 8 12 6 12 9 0 13 4 3 6 1 3 9 6 5 16 13 2 12 7 3 15 5 1 13 6 2 5 9 2 6 5 14 9 38 13 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3625(Uncharacterized enzyme of phosphonate metabolism) 24 25 11 19 4 10 27 0 0 0 0 0 0 0 0 0 0 2 0 1 8 3 11 3 6 0 0 0 0 0 4 0 0 0 0 0 2 144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1646(Predicted phosphate-binding enzymes, TIM-barrel fold) 2 7 47 14 1 0 0 2 4 0 0 0 2 2 6 1 0 2 2 6 8 15 12 4 8 28 4 6 6 3 4 9 12 9 8 19 8 9 4 6 1 9 0 0 0 0 0 0 0 0 0 1 0 0 0 12 NOG06506() 16 20 16 13 3 6 9 4 0 0 1 0 0 12 6 7 4 3 5 13 3 8 5 7 4 6 7 11 9 4 4 15 7 0 28 11 3 20 1 3 3 0 0 0 0 0 0 0 0 0 0 3 0 1 0 2 COG3121(P pilus assembly protein, chaperone PapD) 262 0 1 0 0 0 0 2 1 0 4 2 2 4 2 0 2 1 2 0 1 0 1 0 1 4 1 0 1 0 2 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07815() 232 12 2 0 3 0 0 0 0 0 9 3 0 4 0 0 0 0 2 0 0 0 0 4 0 0 1 0 1 0 0 0 0 0 0 0 2 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21775() 3 19 28 13 2 3 4 8 4 0 10 2 2 9 5 3 0 0 2 13 1 0 13 7 2 0 3 6 5 2 0 9 15 11 20 26 10 19 5 7 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG08893(Major facilitator superfamily protein) 18 6 9 10 3 3 1 13 2 7 1 2 2 21 2 6 7 9 11 4 3 5 10 6 1 5 4 2 6 1 0 13 14 6 16 14 2 21 6 9 6 0 0 0 0 0 0 0 0 0 0 3 0 0 0 11 NOG16348() 0 2 3 1 0 0 0 0 0 5 0 1 6 2 2 0 4 2 0 2 2 15 17 9 0 2 10 5 11 1 4 14 66 11 0 16 0 3 15 22 15 16 0 0 0 0 0 0 0 0 0 5 0 0 0 12 NOG08819() 42 13 14 7 1 0 1 6 1 3 1 2 4 6 4 10 7 4 1 5 4 1 8 3 7 0 4 0 1 0 2 12 3 4 26 16 0 65 4 6 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08005(Ectoine hydroxylase) 3 9 15 20 3 3 2 5 0 1 0 1 0 16 4 5 9 7 5 13 2 7 18 13 6 18 8 1 8 2 2 4 8 6 4 42 0 20 2 2 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3083(Predicted hydrolase of alkaline phosphatase superfamily) 57 27 41 16 0 1 1 0 0 0 2 3 3 10 2 0 4 2 2 4 3 3 3 5 3 2 11 0 4 2 0 6 0 2 10 29 9 13 4 4 5 4 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG06196(Glucans biosynthesis protein C) 10 8 19 15 1 16 0 15 3 1 1 0 1 8 2 1 0 4 4 5 14 6 11 7 3 2 1 3 9 1 4 8 1 2 16 9 2 61 5 5 1 9 0 0 0 0 0 0 2 0 0 4 0 0 0 0 COG2101(TATA-box binding protein (TBP), component of TFIID and TFIIIB) 2 6 25 8 0 0 0 1 3 0 0 1 3 16 18 1 1 1 5 14 11 17 12 9 4 20 5 3 4 1 5 8 16 8 0 19 16 1 3 3 7 6 0 0 0 0 0 0 0 0 0 3 0 0 0 14 NOG16716() 6 8 9 8 1 2 4 16 8 0 0 7 4 2 0 1 6 6 2 23 6 3 12 6 6 4 8 10 5 0 9 12 6 7 26 13 3 25 3 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 COG1918(Fe2+ transport system protein A) 21 6 14 5 0 0 4 2 1 3 0 11 10 7 5 3 3 9 4 3 5 7 15 3 3 10 4 6 1 0 9 6 9 7 6 19 4 57 4 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG25322() 6 0 2 8 2 4 0 1 1 0 2 0 2 13 1 0 0 0 6 4 12 7 7 4 0 36 3 2 0 6 3 9 7 8 4 14 2 96 8 4 2 5 0 0 0 0 0 0 0 0 0 7 0 0 0 0 COG3285(Predicted eukaryotic-type DNA primase) 255 8 10 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 0 0 3 0 0 0 2 0 0 0 0 2 1 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2960(Uncharacterized protein conserved in bacteria) 73 4 5 8 1 4 4 4 0 3 7 1 1 12 2 0 6 7 3 2 4 0 9 6 3 6 5 4 7 2 4 6 8 4 14 11 13 15 6 14 0 5 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG20600(Carboxysome protein) 10 2 0 8 1 4 0 0 0 0 0 0 0 2 0 0 0 0 1 2 20 3 14 9 20 0 3 3 8 12 12 9 3 2 0 1 1 137 8 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4222(Uncharacterized protein conserved in bacteria) 19 13 6 3 9 2 4 0 0 0 2 0 0 10 2 0 6 3 3 1 9 1 18 7 9 19 2 0 0 1 0 0 0 0 0 0 4 144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27089() 1 6 9 5 0 0 4 23 3 6 17 8 2 0 7 3 9 20 7 5 3 5 6 5 4 42 5 2 6 2 1 16 8 9 11 14 0 2 7 7 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG1837(Predicted RNA-binding protein (contains KH domain)) 2 6 17 6 1 0 0 0 0 0 0 2 0 1 2 1 11 16 3 2 2 1 8 1 3 54 7 1 0 1 1 2 0 0 0 3 13 125 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3609(Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain) 78 9 1 1 0 0 0 0 0 0 1 1 0 0 0 1 0 1 1 1 1 3 2 1 2 2 0 1 2 2 0 2 4 0 0 2 2 167 1 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4982(3-oxoacyl-[acyl-carrier protein] reductase) 4 4 13 7 6 5 5 0 1 4 4 0 0 15 4 0 0 0 0 5 0 3 3 12 9 20 6 1 2 7 8 24 5 8 8 14 14 51 7 11 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG11637() 1 3 11 6 9 1 7 9 6 2 5 5 2 7 3 3 1 6 4 2 0 7 7 2 4 3 0 9 5 1 4 13 12 9 49 30 3 5 0 25 6 3 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG23833() 1 1 12 7 4 1 3 8 1 3 5 3 2 5 4 1 7 9 6 2 4 15 9 1 1 12 1 5 7 2 3 10 15 9 29 34 2 17 2 7 1 10 0 0 0 0 0 0 0 0 0 8 0 0 0 7 COG0641(Arylsulfatase regulator (Fe-S oxidoreductase)) 147 3 7 2 2 1 4 0 0 1 2 2 0 1 0 0 0 4 3 2 2 1 3 0 1 7 0 0 0 1 1 5 4 0 2 5 25 52 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG16286() 3 1 3 0 0 0 2 0 0 0 0 0 0 6 3 12 1 2 8 9 6 6 6 6 9 11 11 13 3 0 2 6 7 5 2 22 4 92 2 3 4 4 0 0 0 0 0 0 0 0 0 3 0 0 0 19 COG4420(Predicted membrane protein) 15 3 14 0 0 0 1 0 0 0 0 1 0 3 0 2 26 34 5 4 7 3 3 2 2 78 2 2 4 0 0 0 0 2 0 6 6 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18921() 0 6 12 4 9 3 11 4 7 5 2 4 7 2 7 3 4 5 7 4 5 3 5 5 5 5 2 10 3 3 1 17 10 6 44 18 2 16 2 20 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG22767() 3 4 15 16 8 1 5 7 2 1 6 5 2 0 2 7 5 2 6 6 6 5 9 6 6 12 2 9 10 0 0 7 3 7 10 20 2 48 1 17 5 2 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG11292() 2 7 10 3 8 2 16 7 1 1 3 3 4 0 7 3 3 1 5 2 4 8 7 5 0 9 2 4 5 0 4 8 12 10 28 41 3 34 0 10 3 2 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG06553(Photosynthetic reaction center L subunit) 5 6 5 1 3 0 1 4 6 0 1 0 0 9 2 0 6 2 5 3 5 0 12 1 5 4 8 7 2 0 8 16 10 7 17 6 2 89 10 8 6 4 0 0 0 0 0 0 0 0 0 5 0 0 0 3 NOG07783() 120 4 0 1 5 0 7 13 0 2 11 2 12 5 4 1 2 5 7 2 2 0 5 0 0 24 3 4 2 3 0 4 7 0 10 2 0 15 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG35975() 9 22 43 17 0 0 1 0 2 8 0 1 0 17 3 4 3 2 7 8 6 3 12 3 5 4 1 2 2 2 3 9 6 11 16 46 7 0 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG17518() 8 10 17 9 6 0 7 8 7 4 0 2 0 9 0 3 0 2 3 2 4 2 8 3 11 2 3 5 0 3 7 10 4 16 43 34 4 3 3 19 6 3 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG04119(Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 EC) 1 0 0 5 0 0 2 20 2 3 0 0 4 0 0 1 0 2 2 7 5 8 37 18 13 18 2 16 15 23 12 4 6 2 14 5 1 0 0 8 5 10 1 0 0 0 0 0 0 0 0 7 0 0 0 15 NOG25503() 65 9 4 4 0 1 0 0 2 5 0 4 2 14 4 4 2 0 7 6 2 0 9 2 5 6 3 4 1 1 4 8 5 13 21 31 7 4 7 11 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 10 COG0827(Adenine-specific DNA methylase) 4 9 5 7 1 2 4 4 1 0 3 0 0 9 0 4 7 22 5 6 0 6 13 2 9 18 0 10 2 4 4 5 12 6 8 22 9 42 10 3 2 4 0 0 0 0 0 0 0 0 0 2 0 0 0 7 COG3788(Uncharacterized relative of glutathione S-transferase, MAPEG superfamily) 44 11 5 6 0 4 1 0 0 2 1 1 0 20 3 5 5 7 7 7 3 2 2 5 1 9 5 0 4 0 1 7 7 2 4 13 5 74 1 6 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG07598() 6 7 9 3 0 0 12 0 6 0 0 2 1 8 10 7 1 0 1 5 6 6 20 8 10 1 7 12 5 0 1 11 11 6 11 24 0 25 12 5 8 7 0 0 0 0 0 0 0 0 0 5 0 0 0 14 COG1258(Predicted pseudouridylate synthase) 5 9 13 7 0 2 0 0 0 2 0 6 0 3 8 0 0 0 3 5 4 8 16 11 6 9 7 11 7 1 6 7 25 10 0 33 9 0 9 11 17 3 0 0 0 0 0 0 0 0 0 0 0 0 0 20 COG2821(Membrane-bound lytic murein transglycosylase) 105 5 3 5 3 2 1 0 1 0 1 2 6 14 9 5 17 9 7 4 1 2 4 2 2 16 2 2 5 0 1 3 0 2 4 6 8 25 0 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG29169() 1 2 5 0 21 1 5 0 7 5 13 6 0 0 2 2 6 5 5 4 2 3 10 4 2 4 2 7 1 1 5 18 11 12 26 25 4 11 17 12 5 3 0 0 0 0 0 0 0 0 0 4 0 0 0 13 COG1397(ADP-ribosylglycohydrolase) 62 4 13 7 1 3 0 2 1 2 1 0 1 2 2 2 1 5 3 5 0 3 5 0 4 20 3 0 2 0 0 2 0 0 4 12 7 108 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG4446(Uncharacterized protein conserved in bacteria) 16 5 8 26 4 4 2 0 0 0 0 0 0 1 0 0 0 1 5 3 21 10 23 14 15 2 1 6 13 19 21 13 4 2 2 0 2 22 15 2 2 1 0 0 0 0 0 0 0 0 2 3 0 0 1 0 NOG07681() 24 7 5 14 1 5 1 3 2 0 0 0 1 0 0 0 0 0 0 4 21 12 22 16 11 0 3 6 11 18 11 16 3 0 6 4 0 26 33 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 COG3713(Outer membrane protein V) 234 4 0 0 0 0 0 5 1 0 1 0 0 3 0 0 0 1 3 1 3 1 2 2 1 3 0 0 0 0 2 2 1 0 0 0 2 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11639() 2 4 5 4 13 1 9 5 2 1 6 2 6 2 0 1 1 6 6 3 3 3 11 0 2 11 7 6 4 1 2 14 11 18 27 21 9 24 7 16 4 6 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG2178(Predicted RNA-binding protein of the translin family) 8 16 15 11 0 2 5 0 0 0 0 0 0 5 2 0 3 1 3 8 7 6 7 9 9 7 8 11 7 1 8 8 8 9 13 36 11 1 6 3 7 6 0 0 0 0 0 0 0 0 0 4 0 0 0 20 NOG12524() 1 0 1 2 0 0 0 0 2 0 0 0 2 4 0 0 14 36 3 2 2 2 1 3 0 66 2 0 0 0 0 0 2 2 4 14 0 114 3 0 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG10835() 14 18 20 14 2 2 6 0 1 1 3 0 0 0 0 1 0 2 6 8 6 4 16 12 7 1 16 9 5 0 4 7 3 7 18 6 2 22 6 6 3 9 0 0 0 0 0 0 0 0 0 6 0 0 0 18 NOG08493(Glucosylglycerol 3-phosphatase) 24 9 1 13 3 8 1 0 2 0 0 0 0 0 0 0 0 0 0 2 26 4 30 12 18 0 1 4 14 19 15 7 3 2 7 0 0 36 23 2 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1227(Inorganic pyrophosphatase/exopolyphosphatase) 59 3 4 2 0 3 2 9 1 5 0 2 4 7 0 1 0 4 7 4 0 0 1 0 2 11 2 6 0 0 1 9 9 7 28 8 11 44 6 13 1 2 0 0 0 0 2 0 0 0 0 2 0 0 0 8 NOG06547(BNR repeat protein) 19 14 26 7 2 4 9 1 7 0 3 7 2 3 10 3 7 17 5 3 1 9 7 2 6 10 3 4 1 1 5 6 3 1 24 39 2 1 6 7 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3654(Prophage maintenance system killer protein) 13 0 0 1 0 1 0 3 1 0 3 0 3 7 0 2 5 5 6 0 0 0 0 1 0 14 1 0 0 0 0 1 0 0 0 0 4 218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4657(Predicted NADH:ubiquinone oxidoreductase, subunit RnfA) 26 5 3 3 2 2 0 3 0 1 4 2 0 11 2 2 12 3 2 0 1 3 4 1 4 1 3 0 1 1 0 7 1 3 8 10 15 137 3 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG24751() 11 3 13 13 0 13 3 4 0 2 1 1 0 15 8 3 0 4 13 13 8 6 5 0 3 7 1 11 3 10 5 9 5 2 2 15 1 58 4 3 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG22441() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 2 0 0 0 0 0 2 0 0 0 2 0 2 2 0 8 266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14527(Beta-Carotene hydroxylase) 1 5 22 5 7 0 3 4 9 1 10 2 2 12 4 3 8 4 5 5 3 6 8 3 4 13 0 9 3 0 2 6 10 9 28 21 2 13 2 24 6 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3510(Cephalosporin hydroxylase) 45 9 6 8 0 1 1 3 2 1 2 1 1 1 4 0 6 8 4 1 4 9 7 2 4 22 5 2 6 7 2 4 3 5 6 13 4 65 7 1 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG4627(Uncharacterized protein conserved in bacteria) 5 5 14 12 0 2 2 8 0 1 0 2 2 6 2 6 1 6 6 12 9 3 7 6 6 16 2 6 7 2 0 11 3 8 10 31 4 22 8 8 5 1 0 0 0 0 0 0 0 0 0 9 0 0 2 11 COG4704(Uncharacterized protein conserved in bacteria) 13 17 13 15 2 3 1 6 1 3 0 4 6 4 7 5 2 0 7 5 6 1 7 3 9 6 5 1 2 1 1 14 12 11 24 25 3 21 5 3 2 3 0 0 0 0 0 0 0 0 0 4 0 0 0 6 NOG13020() 1 17 50 8 3 1 3 3 9 1 4 5 0 8 3 3 1 4 1 9 6 4 12 6 1 2 11 7 9 3 3 11 8 4 2 11 1 13 5 6 6 5 0 0 0 0 0 0 0 0 0 5 0 0 0 13 COG5328(Uncharacterized protein conserved in bacteria) 2 6 8 17 0 3 3 0 1 5 4 1 0 8 2 4 0 2 6 6 7 2 6 4 1 1 9 4 1 0 1 12 10 17 31 10 0 56 5 12 3 2 0 0 0 0 0 0 0 0 0 9 0 0 0 7 COG2314(Predicted membrane protein) 53 8 15 5 5 0 3 2 1 0 0 0 0 6 2 0 6 11 0 2 12 3 6 0 2 2 10 0 2 0 2 2 7 1 6 12 4 65 2 5 1 3 0 0 0 0 0 0 0 0 0 3 0 0 0 19 NOG18298() 4 10 27 11 7 1 2 2 4 7 0 3 3 1 4 5 2 2 2 9 2 11 8 3 9 4 1 9 1 2 2 7 8 8 33 25 3 6 7 18 5 1 0 0 0 1 0 0 0 0 0 3 0 0 0 5 NOG14991(Photosynthetic reaction center H subunit) 9 5 4 5 1 2 5 1 3 2 0 0 7 8 0 3 1 1 1 7 5 1 5 2 3 12 4 5 2 0 2 18 5 4 26 12 3 74 5 13 5 7 0 0 0 0 0 0 0 0 0 4 0 0 0 6 NOG15001() 2 2 4 5 0 1 0 3 0 0 1 1 1 0 2 3 5 6 5 7 8 9 11 3 7 31 10 5 4 7 2 6 7 3 8 20 0 62 6 4 2 0 0 0 0 0 0 0 0 0 0 7 0 0 0 17 NOG08587() 6 1 2 3 0 1 3 8 2 3 1 2 2 14 4 1 20 8 6 1 2 2 6 0 2 11 6 3 1 3 5 5 18 10 13 10 0 60 9 14 2 9 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG4213(ABC-type xylose transport system, periplasmic component) 81 1 2 1 0 0 1 4 5 2 3 0 1 1 2 3 18 22 2 2 0 3 1 0 0 73 1 2 4 0 0 1 0 0 2 2 0 42 3 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3569(Topoisomerase IB) 52 17 12 6 0 1 0 12 5 0 1 2 1 10 2 4 8 11 1 3 8 5 16 2 5 21 0 4 5 2 1 3 7 2 2 20 7 12 0 3 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 9 NOG10038() 1 6 29 11 1 1 3 5 3 5 6 4 2 24 4 2 9 16 8 5 1 1 2 3 3 14 11 4 0 1 5 4 3 4 7 17 3 47 3 1 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG4923(Uncharacterized conserved protein) 7 8 11 8 1 0 1 7 4 0 0 3 2 8 4 3 3 9 9 5 10 6 6 6 6 4 3 5 3 0 4 11 7 4 9 9 0 90 0 3 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG15332(Carboxysome protein) 13 3 0 4 0 4 2 0 0 0 0 0 0 1 0 0 0 0 1 1 19 2 16 11 22 0 1 2 8 11 10 7 3 2 0 1 2 129 8 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3737(Uncharacterized conserved protein) 52 7 23 7 0 7 0 2 1 3 4 0 3 6 0 4 14 13 7 3 1 4 0 1 10 12 8 1 3 1 2 5 4 1 4 12 2 40 5 8 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG05988() 178 6 4 5 1 0 0 9 1 1 0 1 4 4 0 0 5 0 0 2 4 0 9 3 6 0 3 4 0 0 5 0 3 2 6 9 0 5 0 0 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4936(Predicted sensor domain) 145 6 4 3 3 0 0 3 2 5 0 2 0 7 2 2 2 2 3 0 2 1 5 0 3 1 3 6 3 1 0 0 1 4 15 7 10 24 2 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06785(Exodeoxyribonuclease VIII) 26 2 3 3 0 0 1 3 1 5 17 0 4 1 2 2 4 0 3 2 3 3 4 2 0 1 2 3 4 1 0 0 4 2 0 5 5 161 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19117() 3 6 19 7 6 1 8 3 3 6 7 6 0 5 4 1 3 3 3 5 4 6 9 4 3 5 7 6 0 1 5 12 12 10 29 19 6 10 7 12 5 4 0 0 0 0 0 0 1 0 0 3 0 0 0 5 COG4321(Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis) 16 6 2 3 0 1 4 2 2 2 5 1 6 12 0 4 1 1 5 6 1 1 2 0 4 0 13 1 2 2 0 5 6 2 24 19 6 86 5 12 0 5 0 0 0 0 0 0 1 0 0 6 0 0 0 2 COG1750(Archaeal serine proteases) 4 1 10 9 0 0 2 6 0 0 0 6 2 16 0 1 11 5 3 9 6 6 3 6 10 10 13 13 5 2 5 5 4 6 10 27 16 15 7 16 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 10 NOG09857(Curlin associated protein) 67 12 3 4 0 3 3 37 4 12 7 1 3 15 5 4 0 7 8 0 2 0 3 2 1 14 0 0 5 0 0 7 5 8 6 7 6 2 4 6 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG1759(ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)) 0 9 24 13 0 0 0 0 1 1 0 1 3 8 15 2 0 2 0 5 2 7 3 5 0 23 4 4 4 6 2 18 20 10 2 15 17 5 5 11 9 2 0 0 0 0 0 0 0 0 0 8 0 0 0 18 NOG17231() 3 11 7 6 6 1 11 4 3 1 5 3 2 5 3 5 4 1 4 0 3 3 9 4 1 1 2 8 4 2 1 15 5 5 38 30 13 28 12 7 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG3850(Signal transduction histidine kinase, nitrate/nitrite-specific) 37 10 19 4 1 2 0 0 2 0 2 0 2 15 0 1 1 0 6 1 9 11 5 3 3 10 4 3 3 2 6 10 6 11 32 12 6 16 10 11 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 COG1599(Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins) 1 13 34 4 4 1 10 0 1 0 0 3 2 6 2 1 0 2 2 12 11 12 12 4 3 25 6 2 5 7 4 10 9 5 0 18 15 0 1 9 12 0 0 0 1 0 0 0 0 0 0 0 0 0 0 13 NOG05972() 237 10 1 3 1 1 0 0 0 0 1 0 0 2 0 0 8 2 0 0 0 0 0 1 0 3 3 0 2 0 2 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG06248() 6 13 12 15 0 2 4 2 0 1 1 0 0 3 2 2 3 7 3 8 11 7 4 3 1 13 13 8 11 8 0 17 9 5 14 20 3 23 3 3 8 4 0 0 0 0 0 0 0 0 0 4 0 0 0 6 COG5146(Pantothenate kinase, acetyl-CoA regulated) 11 32 28 22 1 1 11 0 2 7 0 0 2 3 0 1 1 0 1 3 4 8 18 5 9 0 2 5 11 3 3 10 9 1 28 15 0 1 7 8 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG31975(Reductase) 17 5 6 21 2 1 0 0 1 2 0 0 0 0 3 0 0 0 2 4 13 17 27 14 24 0 0 3 7 9 17 13 3 3 5 5 1 16 19 2 6 0 0 0 0 0 0 0 0 0 0 7 0 1 0 5 NOG16941() 45 7 10 6 2 3 4 3 2 2 2 0 4 7 2 2 8 2 1 1 1 4 3 4 3 1 5 6 1 1 5 11 2 2 12 7 2 82 5 0 1 6 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG1942(Uncharacterized protein, 4-oxalocrotonate tautomerase homolog) 51 11 8 24 0 1 6 9 1 3 0 0 0 4 1 2 6 11 2 4 0 13 5 8 4 2 1 9 4 1 10 9 8 4 23 17 3 1 4 7 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG21636() 12 14 22 13 2 1 2 9 6 0 7 5 5 6 4 6 8 10 4 3 7 4 6 8 0 15 8 5 0 3 5 7 5 2 18 20 1 19 2 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3093(Plasmid maintenance system antidote protein) 35 5 2 0 0 0 0 2 0 2 2 0 2 5 2 4 3 8 1 0 0 0 0 0 0 15 2 0 0 2 0 0 0 0 0 0 13 173 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3746(Phosphate-selective porin) 8 2 9 3 0 0 0 4 4 9 7 0 4 12 0 7 11 6 12 1 4 7 2 2 2 13 5 1 3 1 1 8 4 4 12 16 9 71 1 8 3 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3254(Uncharacterized conserved protein) 20 14 18 13 3 3 4 2 0 0 0 1 0 9 8 1 12 17 6 1 8 4 12 1 7 17 2 6 7 3 6 9 1 2 5 15 2 23 5 2 1 0 0 0 0 0 0 0 0 0 0 9 0 0 0 1 COG2915(Uncharacterized protein involved in purine metabolism) 50 6 6 4 1 0 3 6 4 2 1 1 1 14 0 0 1 2 7 0 3 3 2 2 3 0 1 0 2 0 1 2 1 2 6 12 18 110 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3517(Uncharacterized protein conserved in bacteria) 162 4 0 4 1 1 2 0 0 0 5 0 1 6 0 0 2 2 0 2 0 0 4 0 0 1 2 0 2 0 3 2 1 4 0 4 2 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11010() 9 15 33 13 2 1 3 2 1 0 0 0 0 2 0 0 2 5 6 2 3 4 3 3 5 13 0 1 1 1 3 6 3 4 14 11 16 68 0 7 4 6 0 0 0 0 0 0 0 0 0 0 0 0 1 7 COG3404(Methenyl tetrahydrofolate cyclohydrolase) 3 6 44 6 2 2 1 0 0 3 4 0 5 3 4 0 2 0 4 10 14 10 16 5 5 5 8 9 9 6 4 9 9 9 5 16 1 4 0 12 6 5 0 0 0 0 0 0 0 0 0 10 0 0 0 3 COG3259(Coenzyme F420-reducing hydrogenase, alpha subunit) 114 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 1 1 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 16 140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2302(Uncharacterized conserved protein, contains S4-like domain) 25 7 2 19 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 26 10 18 16 29 1 1 6 12 13 11 17 4 4 0 1 0 38 10 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4158(Predicted ABC-type sugar transport system, permease component) 127 2 4 1 0 0 0 0 2 0 0 2 0 2 0 0 4 16 5 0 5 2 4 1 0 20 1 2 4 0 2 2 1 0 5 2 20 26 3 4 0 3 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG1311(Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B) 5 11 18 9 1 0 0 0 5 0 0 2 2 3 6 2 1 1 3 9 4 12 8 6 8 4 14 4 1 2 4 11 15 6 2 12 31 2 3 4 16 3 0 0 0 0 0 0 0 0 0 3 0 0 0 24 NOG27206() 1 6 4 6 7 2 8 4 5 5 3 5 2 8 7 5 1 5 6 3 5 7 10 3 4 6 6 11 2 2 2 14 14 10 28 23 3 2 4 11 2 8 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG17411() 14 25 31 25 1 1 7 7 1 4 0 0 1 2 4 0 0 0 3 8 5 5 19 10 11 0 1 0 10 2 1 5 9 2 24 10 0 0 8 5 1 6 0 0 0 0 0 0 0 0 0 6 0 0 0 3 NOG11932() 3 3 4 3 0 2 3 3 1 0 2 0 0 10 4 2 8 1 7 3 1 2 1 1 5 10 4 3 6 0 2 10 11 11 15 14 1 81 7 13 3 5 0 0 0 0 0 0 0 0 0 6 0 0 0 6 NOG09720(Succinate dehydrogenase, cytochrome) 2 8 13 6 6 2 9 5 6 3 6 2 3 2 2 4 7 11 2 4 5 9 7 5 5 2 6 6 3 0 2 12 8 12 18 13 3 7 12 21 6 5 0 0 0 0 0 0 0 0 0 6 0 0 0 1 NOG11645() 3 4 8 5 10 0 5 2 6 4 2 7 0 4 4 3 2 6 5 2 4 11 10 4 6 6 4 14 4 1 2 18 8 2 34 23 3 5 7 16 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG1461(Predicted kinase related to dihydroxyacetone kinase) 2 3 30 1 1 0 0 0 0 0 0 0 0 2 2 1 16 19 7 0 1 14 14 4 0 62 2 1 1 0 0 6 1 2 12 25 3 39 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11064(Phage integrase) 261 3 4 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3520(Uncharacterized protein conserved in bacteria) 217 1 1 1 0 0 1 0 0 2 0 0 0 2 0 0 0 0 0 0 1 0 0 2 0 1 2 0 1 0 2 0 0 0 0 0 4 32 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1 3 COG0851(Septum formation topological specificity factor) 55 5 1 7 1 0 0 0 0 0 1 0 0 0 0 1 2 0 1 0 12 0 26 11 6 0 4 6 7 6 10 13 2 2 2 0 1 80 6 0 0 2 0 0 0 0 0 0 0 0 0 6 0 0 0 0 COG2363(Uncharacterized small membrane protein) 25 8 26 7 3 4 2 4 4 1 17 2 4 9 2 1 3 2 6 3 5 6 9 5 3 4 3 7 4 1 0 5 8 0 6 10 8 42 0 9 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1276(Putative copper export protein) 31 29 16 13 2 1 0 0 0 1 0 1 2 11 2 0 11 14 9 2 0 2 3 5 5 76 8 2 0 1 1 2 0 0 3 3 0 18 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3263(NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain) 81 10 14 4 0 0 0 1 0 3 0 1 0 6 2 1 4 5 3 2 1 2 1 2 0 4 1 0 0 3 0 8 6 0 4 5 8 78 5 7 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG11575() 8 7 7 10 1 0 11 0 0 1 0 6 2 0 5 11 0 0 2 2 7 2 14 11 10 0 19 11 13 0 6 12 10 9 9 25 3 0 13 3 5 4 0 0 0 0 0 0 0 0 0 4 0 0 0 13 NOG19434() 8 6 13 9 0 0 3 0 2 0 0 3 1 10 8 2 7 0 1 8 11 9 12 5 6 0 14 11 6 0 17 10 11 9 10 10 4 0 14 6 6 2 0 0 0 0 0 0 0 0 0 2 0 0 0 20 NOG09623() 15 10 20 17 0 3 7 7 2 1 1 3 10 3 0 0 2 0 1 9 8 7 19 2 3 0 2 2 4 1 7 5 5 2 21 22 19 10 6 10 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG07998() 10 3 28 12 1 0 3 2 2 2 2 4 1 12 6 2 2 1 3 5 0 0 4 6 7 0 7 1 1 0 3 17 8 5 14 28 0 43 1 8 5 7 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG1554(Trehalose and maltose hydrolases (possible phosphorylases)) 3 0 2 2 7 3 2 3 4 10 0 10 3 5 6 3 2 9 0 1 2 3 4 2 0 3 5 10 0 5 4 13 6 6 23 6 11 65 4 13 5 4 0 0 0 0 0 0 2 0 0 2 0 0 0 2 NOG11369() 4 2 3 3 7 4 1 1 7 0 0 1 6 3 6 0 2 3 3 9 8 7 14 4 2 7 5 6 2 4 7 16 11 6 30 20 6 6 5 30 6 4 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG09455() 22 2 6 19 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 2 29 5 26 18 26 1 1 6 9 8 8 14 3 0 9 0 0 30 19 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG35037() 27 7 1 15 2 1 7 0 0 0 0 0 0 0 0 0 0 0 0 2 30 12 22 16 19 0 2 2 15 17 24 7 2 2 8 0 0 14 12 1 0 0 0 0 0 0 0 0 0 0 2 5 0 0 0 0 NOG17218() 32 23 35 13 3 0 4 2 2 0 1 0 0 10 0 1 0 0 1 1 1 3 10 8 6 4 4 3 4 7 5 14 5 3 28 12 2 5 6 5 2 1 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG2859(Uncharacterized protein conserved in bacteria) 15 4 0 6 0 0 0 0 2 0 0 1 0 2 0 0 18 27 1 4 9 1 5 7 12 77 0 4 5 4 6 3 2 0 3 3 2 36 2 4 0 0 0 0 0 0 0 0 0 0 2 6 0 0 0 0 COG5135(Uncharacterized conserved protein) 26 7 6 16 2 3 2 0 0 1 0 4 0 0 0 2 0 0 1 0 16 2 17 8 21 3 4 5 4 13 18 11 5 2 12 2 2 32 10 7 1 4 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG4587(ABC-type uncharacterized transport system, permease component) 17 3 2 14 3 5 0 1 0 0 0 0 0 2 0 3 0 2 1 2 13 9 26 8 24 7 2 1 12 13 15 8 7 2 3 3 4 19 29 1 0 0 0 0 0 0 0 0 3 0 0 3 0 2 0 4 COG2240(Pyridoxal/pyridoxine/pyridoxamine kinase) 67 0 4 5 3 1 9 5 0 4 3 0 4 5 2 1 4 0 2 0 2 2 1 0 0 5 10 3 2 0 2 5 6 10 20 4 2 53 2 8 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 8 COG4965(Flp pilus assembly protein TadB) 148 0 0 0 0 0 1 0 2 0 0 0 0 2 0 3 2 2 0 0 0 0 1 0 0 9 4 0 2 0 0 1 1 0 2 1 2 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3587(Restriction endonuclease) 149 8 0 2 0 0 0 0 0 0 0 4 4 0 2 0 3 11 2 0 0 4 0 1 1 7 4 0 0 2 0 0 2 1 6 0 3 53 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG32623() 4 2 19 3 7 0 3 0 4 0 6 1 2 8 2 2 4 1 4 3 9 2 7 2 0 7 2 4 7 1 6 12 13 11 40 20 6 14 0 16 6 4 0 0 0 0 0 0 0 0 0 0 0 0 0 8 NOG24838() 0 4 9 0 8 0 0 8 8 0 8 2 0 16 4 1 10 3 4 4 4 4 5 5 6 19 4 0 0 2 2 4 1 0 0 16 1 93 1 5 2 1 0 0 0 0 0 0 0 1 0 3 0 0 0 4 COG4675(Microcystin-dependent protein) 168 2 1 0 0 1 2 5 0 0 1 1 4 2 2 1 4 2 0 1 2 1 3 3 0 15 2 0 3 2 2 2 2 4 0 4 4 11 0 11 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 NOG14449() 5 10 7 4 14 0 10 1 2 4 3 3 3 4 5 2 1 4 3 5 4 4 10 7 11 1 2 3 5 2 2 10 8 9 27 42 1 6 1 14 3 4 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG1944(Uncharacterized conserved protein) 74 4 1 0 0 0 0 0 3 2 2 0 7 5 2 1 16 8 0 0 0 1 3 0 0 0 0 0 1 0 0 0 0 0 0 4 30 104 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3727(DNA G:T-mismatch repair endonuclease) 49 4 18 9 0 2 2 2 0 1 0 1 0 2 2 1 2 3 2 5 3 12 9 2 2 19 2 5 4 6 7 2 4 2 1 17 12 43 4 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 6 NOG10787() 29 6 1 20 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 2 10 7 20 14 25 1 0 3 9 22 19 14 2 1 3 5 0 17 23 2 0 4 0 0 0 0 0 0 0 0 0 6 0 0 0 0 NOG09575(Collagen triple helix repeat protein) 1 3 11 8 2 6 0 7 4 3 8 5 7 8 4 0 11 5 6 2 0 3 6 8 1 37 6 1 0 0 4 3 12 6 4 14 6 23 4 4 8 1 0 0 0 0 0 0 0 0 0 1 0 0 0 18 NOG14459() 2 6 15 5 10 1 4 5 4 2 0 3 2 12 2 6 2 1 1 5 10 6 3 8 9 11 6 6 2 0 1 10 15 7 22 25 0 4 1 15 8 3 0 0 1 0 0 0 0 1 0 6 0 0 0 3 NOG21903() 13 10 18 19 1 1 0 0 0 0 1 0 3 0 0 0 0 2 1 3 15 3 31 11 26 0 2 19 14 14 17 9 5 8 7 3 0 5 6 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06026() 239 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 1 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1708(Predicted nucleotidyltransferases) 85 2 10 2 0 1 2 2 0 0 4 1 0 3 2 1 3 5 3 2 3 0 1 1 5 7 1 2 1 0 1 3 3 0 8 4 31 61 0 4 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG06565(Type III restriction-modification enzyme) 4 10 10 6 0 0 9 3 1 0 2 2 0 3 0 3 5 2 1 0 2 3 3 6 6 23 0 11 1 0 4 1 2 0 7 16 7 89 3 6 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 8 COG3151(Uncharacterized protein conserved in bacteria) 31 4 11 5 0 0 2 8 4 3 9 0 0 4 0 2 6 1 6 2 0 1 6 2 3 0 3 2 4 0 2 2 2 0 5 6 14 108 1 4 2 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5006(Predicted permease, DMT superfamily) 73 7 2 1 0 0 0 0 0 0 0 0 0 3 2 0 7 17 0 2 3 0 3 0 0 44 2 3 1 0 0 0 0 0 0 5 1 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2836(Uncharacterized conserved protein) 56 9 4 0 3 0 0 5 0 2 3 0 0 4 0 1 7 17 1 1 0 0 2 2 0 18 1 0 0 0 0 0 0 0 0 5 20 106 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5373(Predicted membrane protein) 243 1 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 1 0 2 0 0 0 2 1 0 0 1 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5337(Spore coat assembly protein) 1 5 55 8 2 3 0 0 13 4 0 2 2 3 0 2 7 0 2 4 5 17 3 4 5 11 10 7 1 0 1 11 8 8 4 28 5 7 0 8 1 4 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG09611() 44 10 21 4 2 1 0 3 2 0 17 0 0 12 10 3 1 0 10 5 3 2 10 4 2 2 10 5 3 0 0 2 2 0 2 6 8 51 4 3 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 COG4338(Uncharacterized protein conserved in bacteria) 4 3 3 8 2 1 4 1 3 1 2 1 1 11 2 1 6 8 1 3 5 2 0 4 1 15 3 1 0 2 0 6 4 7 11 10 0 121 3 1 1 0 0 1 0 0 0 0 0 0 0 3 0 0 0 0 COG4660(Predicted NADH:ubiquinone oxidoreductase, subunit RnfE) 42 4 1 0 0 0 3 0 2 4 4 0 4 3 2 2 2 2 13 2 0 0 5 1 3 2 0 0 0 0 2 3 2 2 2 12 9 127 1 1 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3324(Predicted enzyme related to lactoylglutathione lyase) 181 4 0 2 5 0 1 0 0 0 3 1 0 2 0 0 2 6 2 1 0 1 2 2 0 2 0 0 1 1 3 3 2 0 2 2 9 20 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG13032() 58 11 1 23 1 3 0 0 0 0 0 0 0 0 0 0 0 0 2 2 2 1 14 5 3 4 0 7 1 2 4 0 3 2 18 7 0 81 3 1 3 1 0 0 0 0 0 0 0 2 0 1 0 0 0 0 COG1470(Predicted membrane protein) 129 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 13 23 19 6 3 0 1 0 1 0 2 3 10 2 0 4 0 24 0 4 1 2 0 0 0 0 0 0 0 0 0 6 0 0 0 4 COG5560(Ubiquitin C-terminal hydrolase) 1 7 7 8 10 10 0 14 4 3 0 4 11 10 4 1 14 13 8 22 7 3 8 3 10 24 5 0 3 11 1 4 4 3 3 12 7 2 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4795(Type II secretory pathway, component PulJ) 152 15 3 2 1 0 2 5 0 0 1 5 1 6 3 1 2 0 4 5 0 1 3 1 0 4 0 0 1 3 2 4 1 0 2 6 7 19 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG06504() 0 0 0 0 0 0 0 0 1 0 0 0 3 0 0 0 8 9 4 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 234 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08462() 20 12 7 14 2 4 0 0 0 0 0 0 0 3 2 0 0 2 3 4 14 4 24 15 22 3 5 3 9 20 14 7 0 2 4 3 0 21 12 1 2 0 0 0 0 2 0 0 0 0 0 4 0 0 0 1 COG3144(Flagellar hook-length control protein) 145 11 1 0 0 2 0 2 1 6 2 1 0 3 4 1 0 0 7 0 1 0 2 2 3 1 2 2 2 0 2 0 2 0 0 2 4 48 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG5515(Uncharacterized conserved small protein) 7 5 9 13 0 0 2 5 5 8 2 6 3 7 6 7 8 3 11 7 1 1 5 4 7 0 8 5 3 0 4 9 8 7 27 23 6 4 5 10 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG4843(Uncharacterized protein conserved in bacteria) 6 2 2 3 0 0 7 4 1 2 0 4 0 2 4 5 2 1 3 6 6 6 13 14 10 0 12 4 7 0 2 14 17 8 13 35 0 5 9 10 7 1 0 0 0 0 0 0 0 0 0 5 0 0 0 12 NOG07687() 26 4 6 20 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 12 19 17 27 1 0 5 9 13 9 13 4 2 4 1 0 19 21 2 0 0 0 0 0 0 0 0 0 0 0 6 0 0 2 1 NOG11933(2-Vinyl bacteriochlorophyllide hydratase) 2 5 3 3 0 1 1 2 3 2 4 0 2 12 9 3 9 3 2 4 4 5 7 1 2 2 1 4 3 0 2 15 11 10 20 19 0 66 4 8 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG35294() 3 15 6 4 4 0 2 0 0 0 0 0 0 88 102 0 1 1 0 0 0 1 1 20 0 1 3 2 0 0 0 0 0 0 0 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1848(Predicted nucleic acid-binding protein, contains PIN domain) 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 2 191 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1910(Periplasmic molybdate-binding protein/domain) 85 2 5 6 0 3 0 4 2 1 0 0 1 9 0 2 4 2 5 1 3 5 1 8 2 1 3 2 0 0 0 1 1 2 0 0 15 77 0 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG21844() 0 31 36 20 1 3 0 20 2 6 0 0 2 0 0 0 4 2 0 4 9 3 26 9 8 3 4 7 10 0 4 8 3 2 0 22 0 0 0 4 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09471() 21 6 2 14 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 11 9 19 17 14 1 4 8 10 9 24 9 1 6 3 0 0 23 25 4 1 4 0 0 0 0 0 0 0 0 2 10 0 0 0 1 COG3115(Cell division protein) 118 5 5 7 2 0 0 7 1 0 12 2 2 17 2 5 7 3 4 3 0 3 1 3 1 3 6 2 2 1 1 3 2 0 2 3 8 17 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4398(Uncharacterized protein conserved in bacteria) 21 3 17 13 0 1 2 3 0 0 0 0 0 4 4 2 2 5 4 3 5 5 6 4 4 8 2 5 3 4 3 11 3 6 0 3 3 73 26 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1317(Flagellar biosynthesis/type III secretory pathway protein) 138 8 6 2 0 1 0 0 0 3 5 0 2 5 2 2 4 4 1 0 0 4 4 5 1 1 2 4 1 6 3 3 7 0 3 2 8 18 0 2 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2764(Uncharacterized protein conserved in bacteria) 188 0 0 0 0 0 0 2 0 0 0 0 0 4 0 2 2 1 1 0 0 0 0 0 0 20 2 0 0 1 0 0 0 2 4 4 4 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3488(Predicted thiol oxidoreductase) 25 16 7 13 2 1 2 8 2 2 3 2 5 5 0 3 7 2 1 5 3 6 5 5 2 5 2 3 3 1 2 8 2 0 11 19 26 35 6 1 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG26295() 1 4 4 7 8 0 10 10 16 1 3 5 0 1 3 4 2 6 3 2 2 2 7 1 3 7 2 5 7 0 1 13 10 7 54 18 1 2 2 12 8 2 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG4725(Transcriptional activator, adenine-specific DNA methyltransferase) 2 6 4 7 2 2 2 9 2 4 0 2 0 3 2 2 4 17 13 2 2 3 7 6 5 12 4 4 7 2 9 15 12 10 4 17 8 32 1 1 3 5 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG09592(Thioesterase superfamily) 0 2 11 4 0 0 0 1 0 0 0 0 0 2 0 4 17 11 0 3 11 12 11 5 3 27 8 10 6 3 4 8 9 2 6 9 18 13 1 10 7 3 0 0 0 0 0 0 0 0 0 5 0 0 0 15 COG4913(Uncharacterized protein conserved in bacteria) 169 1 0 0 0 6 1 0 0 0 0 0 0 2 2 0 0 0 8 5 0 2 0 0 0 0 2 4 0 0 0 1 1 0 0 0 25 30 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1963(Uncharacterized protein conserved in bacteria) 10 7 11 14 3 3 3 0 0 0 0 0 0 1 0 0 0 2 5 5 17 8 20 14 22 2 5 4 6 15 17 9 4 6 2 0 6 21 7 4 0 1 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG1718(Serine/threonine protein kinase involved in cell cycle control) 48 4 16 7 1 0 0 1 4 1 0 2 2 6 10 9 2 1 6 3 4 5 7 4 3 8 4 5 5 7 2 5 13 5 0 14 6 1 0 8 7 9 0 0 0 0 0 0 0 0 0 0 0 0 0 14 COG2914(Uncharacterized protein conserved in bacteria) 77 2 1 0 3 3 0 2 1 3 13 4 0 14 4 5 6 9 6 1 1 0 1 1 1 3 4 0 0 0 2 2 0 0 0 2 15 69 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG05971() 5 4 13 4 0 2 3 7 10 8 3 6 8 28 7 7 7 11 13 4 1 6 6 1 0 10 7 2 1 3 0 1 5 7 11 24 11 8 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25163(L-Arginine:Glycine amidinotransferase) 19 22 11 15 0 2 8 2 2 1 0 4 4 1 2 7 5 4 3 5 4 5 5 2 5 0 3 3 5 0 2 12 3 13 27 27 1 2 3 6 3 3 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG07798() 177 1 3 2 2 1 1 0 2 2 4 0 2 3 2 3 4 4 2 0 5 3 5 0 2 1 0 2 1 1 2 2 1 0 5 4 0 4 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 NOG08459(Photosystem II protein) 22 8 0 24 1 4 2 0 0 0 0 0 1 0 0 0 0 0 0 1 15 8 14 19 10 1 1 3 17 11 16 11 2 2 1 4 0 19 24 0 0 3 0 0 2 0 0 0 0 0 0 8 0 1 0 3 COG1320(Multisubunit Na+/H+ antiporter, MnhG subunit) 13 9 4 5 0 6 8 0 1 1 2 1 4 5 0 1 3 7 4 4 1 4 4 8 9 0 9 1 4 0 2 1 1 2 0 5 17 103 0 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG2981(Uncharacterized protein involved in cysteine biosynthesis) 54 8 3 3 2 2 2 1 4 11 4 0 2 5 3 1 1 0 11 5 4 1 3 0 1 1 2 2 3 0 1 4 2 0 2 1 13 84 5 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG23894(HNH endonuclease) 11 6 2 15 2 5 2 2 0 0 0 0 0 0 0 2 1 0 2 4 17 12 31 16 15 6 9 6 12 18 11 1 0 5 8 0 0 26 0 2 4 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3079(Uncharacterized protein conserved in bacteria) 35 11 15 5 2 3 2 4 1 4 3 0 1 18 7 4 2 0 2 0 0 3 3 3 0 0 1 0 1 0 0 0 1 4 8 21 9 77 3 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG08455(Photosystem I assembly protein) 14 6 5 14 1 9 1 0 0 0 0 0 0 0 2 0 0 0 0 4 13 7 23 11 16 1 5 6 7 18 14 8 3 2 6 4 0 25 20 4 3 0 0 0 0 1 0 0 0 0 0 1 0 0 1 2 COG1180(Pyruvate-formate lyase-activating enzyme) 78 1 11 12 0 0 1 0 0 1 0 2 0 1 4 1 8 2 1 1 1 1 3 3 2 23 13 2 0 0 3 0 0 0 2 3 33 39 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG20059(Cytochrome c, class I protein) 5 6 9 4 5 1 11 4 1 3 3 2 4 2 2 2 4 2 3 2 3 7 6 1 4 0 7 8 0 0 0 18 13 10 49 24 0 0 5 17 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG17142() 233 3 1 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19175(Alpha/Beta hydrolase) 4 12 9 17 0 4 9 3 3 3 0 2 2 4 2 2 0 0 1 3 3 2 4 3 5 18 2 6 4 1 3 16 9 10 22 32 2 0 11 7 3 2 0 0 0 0 0 0 0 0 0 3 0 0 0 8 COG5517(Small subunit of phenylpropionate dioxygenase) 199 8 3 4 2 0 0 0 0 0 0 1 0 1 2 0 7 3 3 1 0 4 1 1 0 8 0 0 1 0 0 1 0 0 0 3 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3624(Uncharacterized enzyme of phosphonate metabolism) 13 13 8 15 5 5 20 0 0 0 0 0 0 0 2 1 1 2 1 1 1 2 6 5 5 1 0 0 0 0 3 0 0 0 0 1 2 142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06103() 56 14 26 7 1 0 2 8 2 4 3 6 9 1 0 0 0 0 1 3 1 3 6 2 6 1 3 1 0 1 2 5 6 8 13 14 0 14 2 14 3 4 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3732(Phosphotransferase system sorbitol-specific component IIBC) 8 5 5 11 0 0 8 8 3 0 0 2 3 18 6 10 9 5 6 0 9 7 10 5 0 4 11 9 5 0 0 7 5 11 2 21 0 0 5 3 7 7 0 0 0 0 0 0 0 0 0 3 0 0 0 18 COG3467(Predicted flavin-nucleotide-binding protein) 61 5 21 9 0 0 0 0 0 0 0 0 0 2 8 4 7 9 6 2 1 2 2 3 6 66 0 0 0 0 0 1 0 0 0 6 3 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 NOG16499() 2 0 3 1 4 2 0 0 0 2 0 0 0 0 0 1 2 0 0 6 0 2 4 1 1 5 5 2 0 0 2 7 2 9 15 11 1 139 8 8 1 4 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG07680(Linker polypeptide) 30 2 1 3 9 4 3 3 0 6 0 0 0 0 0 0 0 0 0 3 5 0 0 1 0 2 7 4 0 4 0 17 1 0 6 0 0 101 40 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG1950(Predicted membrane protein) 50 0 0 0 1 0 1 0 2 0 1 0 0 7 2 1 11 19 4 1 0 0 0 1 0 47 0 0 0 0 0 3 3 0 2 0 3 96 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36158() 5 22 30 15 0 0 4 9 1 3 5 2 5 15 4 4 0 0 3 2 6 4 8 7 5 0 5 3 5 0 1 19 7 8 24 10 0 0 7 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2843(Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)) 1 3 33 9 1 2 2 0 1 1 0 0 0 11 3 2 14 2 3 3 3 4 3 8 11 18 6 3 3 4 1 14 4 2 11 17 11 24 3 9 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3533(Uncharacterized protein conserved in bacteria) 78 9 5 11 4 4 7 3 0 0 0 0 0 2 2 0 0 4 3 4 0 0 10 1 3 11 2 5 0 2 6 3 8 14 10 11 4 5 6 3 3 2 0 0 0 0 0 0 0 0 0 7 0 0 0 3 COG1498(Protein implicated in ribosomal biogenesis, Nop56p homolog) 2 11 35 11 5 7 2 2 1 2 2 3 0 10 14 1 0 0 1 5 7 14 10 1 2 8 1 6 2 7 3 4 8 12 2 13 11 3 0 4 10 8 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG1736(Diphthamide synthase subunit DPH2) 1 7 21 3 0 2 0 0 1 0 0 5 2 14 10 2 0 0 2 5 9 17 13 6 4 9 5 3 4 3 1 17 9 1 0 15 17 0 1 10 15 7 0 0 0 0 0 0 0 0 0 5 0 0 0 9 NOG08002() 9 4 6 7 0 0 3 0 3 0 0 8 1 8 4 9 0 0 1 5 9 10 17 5 7 0 10 11 10 0 7 18 9 4 4 32 0 0 9 6 7 2 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG26868() 12 15 20 26 1 4 0 0 2 2 10 3 3 4 0 0 0 0 2 5 2 1 10 3 2 2 2 7 3 0 2 7 1 7 17 18 2 22 14 10 8 0 0 0 0 2 0 0 0 0 0 0 0 0 0 3 COG3562(Capsule polysaccharide export protein) 141 2 1 1 3 3 2 0 0 2 3 1 3 13 0 2 4 2 3 0 0 0 1 0 2 1 2 2 0 5 2 4 0 0 0 0 0 38 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06249() 114 10 5 6 0 0 0 0 0 1 4 2 0 0 0 3 0 5 1 2 2 0 3 3 2 12 4 0 3 3 1 2 1 0 4 11 0 40 8 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19579() 5 24 29 19 4 0 5 6 5 0 3 2 0 3 6 3 0 0 5 8 8 2 5 2 4 0 7 6 2 1 2 10 5 8 28 5 3 17 0 3 2 4 0 0 0 0 0 0 2 0 0 1 0 0 0 0 NOG19634() 1 1 18 0 0 0 0 0 0 0 0 1 0 2 4 2 0 0 1 12 19 25 16 9 8 2 3 18 0 4 3 17 18 9 0 14 0 0 0 12 10 9 0 0 0 0 0 0 0 0 0 1 0 0 0 14 NOG16997(Rhodanese-Like protein) 3 2 4 4 0 0 0 2 0 1 2 0 5 1 4 0 2 0 2 2 2 0 2 0 1 0 4 1 0 1 0 0 2 0 0 20 35 150 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2271(Sugar phosphate permease) 45 8 22 13 6 1 0 0 1 2 0 2 0 10 2 1 7 5 4 3 2 3 5 4 1 39 7 9 2 4 2 6 2 3 12 4 3 5 3 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1503(Peptide chain release factor 1 (eRF1)) 3 7 20 7 3 5 1 0 0 0 0 1 1 1 8 0 4 0 2 6 8 10 14 4 5 7 3 8 3 7 2 8 10 4 2 8 25 4 3 8 14 10 0 0 0 0 0 0 0 0 0 3 0 0 0 14 COG2718(Uncharacterized conserved protein) 93 7 1 2 4 2 4 0 4 1 0 1 1 4 2 0 9 0 0 1 1 0 9 4 3 21 1 0 3 4 4 2 0 2 0 8 22 25 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG5452(Uncharacterized conserved protein) 5 6 9 10 3 1 3 9 1 5 0 6 5 8 4 1 3 6 4 8 4 2 11 3 8 0 9 1 5 0 4 4 13 3 18 17 1 30 4 15 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2026(Cytotoxic translational repressor of toxin-antitoxin stability system) 47 0 1 0 0 1 0 0 0 1 4 0 0 6 0 0 7 6 2 0 0 0 0 0 0 19 3 0 0 1 0 2 0 0 0 0 28 123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5331(Uncharacterized protein conserved in bacteria) 17 13 25 17 3 1 2 7 2 1 6 2 1 4 10 4 0 0 2 3 5 14 13 10 2 1 9 4 8 3 6 10 6 0 18 7 1 1 3 7 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG18242() 2 6 45 11 3 0 0 2 4 1 4 4 0 6 0 0 0 0 2 2 3 7 5 12 6 0 1 12 7 0 4 5 10 2 21 13 6 7 5 14 1 4 0 0 0 0 0 0 0 0 0 6 0 0 0 8 NOG12582() 7 5 5 4 0 0 3 5 0 0 0 2 0 3 15 1 0 0 6 8 5 10 12 6 10 0 6 18 10 0 3 11 10 6 10 24 3 2 8 2 6 9 0 0 0 0 0 0 0 0 0 1 0 0 0 14 COG2833(Uncharacterized protein conserved in bacteria) 49 2 2 0 1 3 2 1 2 5 3 0 3 17 2 5 8 3 9 3 1 0 1 3 2 6 5 3 2 0 1 6 0 2 3 11 13 51 3 4 6 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG20062() 0 5 9 11 4 1 5 4 9 0 10 1 0 1 0 2 2 6 2 5 3 11 5 2 6 3 4 3 2 1 3 11 9 3 36 23 1 5 8 19 6 4 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG09329() 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 28 33 2 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06273() 0 1 0 0 0 0 0 0 0 0 2 1 0 2 2 7 25 41 6 1 0 0 1 1 0 45 2 0 0 0 2 0 0 0 0 0 1 108 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3735(Uncharacterized protein conserved in bacteria) 131 9 2 1 0 0 0 0 0 2 3 0 3 4 4 2 8 4 6 0 1 0 0 1 0 6 1 0 1 0 0 1 0 0 0 9 5 38 2 0 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG2367(Beta-lactamase class A) 121 2 6 3 1 1 0 0 0 0 2 0 0 5 0 0 2 4 2 0 8 3 3 4 0 4 0 2 1 2 3 7 2 0 0 4 4 35 13 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG14352() 70 5 5 4 1 1 3 6 5 3 0 6 4 6 4 1 8 0 2 2 0 4 7 1 2 7 0 7 6 0 1 5 6 9 10 28 1 7 0 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG4582(Uncharacterized protein conserved in bacteria) 101 12 26 11 3 0 0 1 0 0 1 0 0 2 6 3 14 10 0 1 3 0 1 1 1 13 0 3 3 0 1 1 3 2 2 11 8 1 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG06030(Tryptophan halogenase) 28 17 6 3 0 0 2 10 2 3 2 4 0 14 3 5 0 2 10 3 8 4 19 2 6 10 10 4 3 18 2 7 4 4 14 2 2 2 6 3 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG25806() 2 1 4 5 1 2 0 8 0 0 2 0 4 16 4 6 2 1 13 5 6 5 3 1 1 17 0 6 3 4 1 9 1 6 0 7 1 93 2 2 0 1 0 2 0 0 0 0 0 0 0 2 0 0 0 0 NOG25419() 1 0 16 7 8 0 8 2 2 0 0 1 2 0 1 2 2 3 1 11 5 12 9 6 0 2 6 21 5 0 0 13 8 8 35 23 0 7 2 15 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG3123(Uncharacterized protein conserved in bacteria) 79 6 5 4 0 1 1 0 0 0 0 1 2 3 0 5 9 9 10 1 0 3 3 1 0 5 1 2 0 1 0 3 3 0 10 2 24 49 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3754(Lipopolysaccharide biosynthesis protein) 11 3 2 1 5 3 2 3 0 0 0 1 2 3 0 0 1 8 1 0 4 0 2 0 0 5 5 0 2 2 2 3 2 2 6 0 2 152 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11573(Reductase) 4 6 16 8 6 1 2 13 0 3 9 1 0 22 5 2 4 0 5 10 0 11 25 8 6 2 4 9 0 1 0 3 1 0 11 18 0 12 6 1 0 5 0 0 0 0 0 0 0 0 0 7 0 0 0 0 COG2190(Phosphotransferase system IIA components) 205 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 0 6 5 5 0 0 0 0 0 0 8 0 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG13217() 13 10 6 9 2 0 2 4 3 1 2 7 0 0 2 3 6 4 3 5 2 4 3 3 0 12 1 2 5 2 6 3 14 7 8 20 10 35 7 15 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 2 COG1084(Predicted GTPase) 5 9 14 10 1 1 0 0 0 3 0 1 0 4 0 0 4 2 3 8 6 7 16 7 3 9 4 13 10 8 1 3 15 6 9 19 1 4 0 4 7 10 0 0 2 0 0 0 2 0 0 5 0 0 0 11 COG2909(ATP-dependent transcriptional regulator) 118 1 3 0 0 0 1 7 2 3 0 0 0 2 0 0 7 15 7 0 2 0 0 0 1 14 2 0 4 0 4 0 0 0 2 0 2 47 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17192(Type IV secretion system protein VirB1) 245 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3628(Phage baseplate assembly protein W) 7 2 2 4 0 0 2 13 6 0 5 1 3 2 2 1 1 0 1 3 2 5 17 13 11 23 10 8 8 4 1 7 8 6 6 8 5 8 6 11 6 2 0 0 0 0 0 0 0 0 0 2 0 0 0 14 NOG14741() 4 5 22 5 2 3 3 2 0 3 1 3 5 14 5 4 9 10 8 4 0 0 3 1 2 12 5 0 1 0 0 8 6 8 10 15 3 35 8 10 3 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG06371() 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14439() 5 4 6 2 8 1 13 8 4 0 7 4 0 0 5 3 2 4 2 1 2 4 13 5 0 0 6 4 4 0 4 10 13 3 36 11 3 12 4 23 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG24056() 1 1 3 6 6 1 2 5 4 1 18 1 1 32 8 4 2 6 9 6 0 7 0 7 4 6 1 0 2 2 3 10 0 0 4 12 3 58 1 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG08786() 6 2 9 5 0 3 2 0 0 2 0 2 0 2 2 1 2 4 1 11 10 2 8 9 6 9 3 13 5 2 12 6 10 10 12 24 2 16 6 6 5 2 0 0 0 0 0 0 0 0 0 6 1 1 0 6 COG3694(ABC-type uncharacterized transport system, permease component) 13 7 1 12 2 4 0 0 0 0 0 0 0 1 4 1 0 0 2 1 13 6 18 9 18 10 5 4 16 13 11 6 4 4 0 0 4 18 27 0 0 0 0 0 0 0 0 0 3 0 0 3 0 1 0 5 NOG09660() 2 1 13 7 4 1 7 4 1 0 0 6 0 7 0 3 1 0 1 9 10 5 16 6 5 0 2 7 2 5 0 10 14 0 18 13 2 14 13 12 7 1 0 0 0 0 0 0 0 1 0 5 0 0 0 11 COG1056(Nicotinamide mononucleotide adenylyltransferase) 59 6 16 6 1 0 0 0 0 0 0 0 0 2 4 0 0 1 5 5 9 12 10 7 6 11 3 7 3 1 2 4 4 4 9 7 11 10 2 9 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG16989(Rhodanese Homology Domain) 9 13 16 14 0 1 1 3 3 8 1 3 0 6 0 1 2 0 2 12 4 2 8 6 7 0 1 6 3 1 5 16 6 5 12 15 2 24 9 10 3 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG04726() 23 8 3 22 2 5 1 1 0 0 0 0 0 0 0 0 0 0 0 1 26 5 17 8 18 0 1 10 9 7 17 11 3 0 4 0 0 18 16 3 0 2 0 0 0 0 0 0 0 0 0 2 0 2 0 0 NOG06453(Feruloyl esterase) 156 2 9 7 0 0 0 0 0 0 0 3 0 2 0 2 3 2 3 2 2 4 6 0 2 4 2 0 1 0 2 1 0 2 4 14 3 3 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4857(Predicted kinase) 18 11 11 9 0 5 2 6 0 2 0 0 0 6 0 1 2 0 4 4 7 1 9 4 0 2 4 0 1 0 8 20 12 15 24 7 2 11 5 21 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG26704(Possible porin protein) 15 6 2 5 2 1 1 0 0 0 0 0 2 0 0 0 0 0 1 0 14 1 14 9 11 7 5 5 3 1 6 7 1 2 0 0 0 109 12 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3846(Type IV secretory pathway, TrbL components) 210 1 3 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 4 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3545(Predicted esterase of the alpha/beta hydrolase fold) 198 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 9 10 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 13 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07688() 19 6 3 10 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 3 17 6 19 17 11 0 6 2 8 17 8 9 2 4 5 0 0 40 17 0 1 1 0 0 0 0 0 0 0 0 0 3 0 0 2 1 COG4548(Nitric oxide reductase activation protein) 3 2 18 11 1 2 1 2 5 0 0 5 2 14 4 5 2 2 12 1 0 1 15 2 4 0 0 0 1 0 2 0 5 0 2 27 20 67 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG26212(Possible porin protein) 25 2 2 7 7 5 1 0 0 4 0 0 2 0 0 0 0 0 5 2 29 0 6 3 13 21 2 2 3 7 6 5 0 2 4 2 0 72 3 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 COG2002(Regulators of stationary/sporulation gene expression) 7 3 5 8 1 0 8 0 0 0 0 0 0 0 2 3 4 0 1 4 4 3 15 6 1 2 5 11 2 0 5 8 6 8 3 10 2 84 8 1 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 9 NOG14080() 5 9 11 16 2 2 6 6 4 0 0 3 1 9 5 1 2 1 5 2 5 6 12 7 2 0 7 6 2 0 5 3 16 7 26 12 2 8 7 3 5 4 0 0 0 0 0 0 0 0 0 1 0 0 0 7 NOG19101(Acid phosphatase homologues) 2 7 8 6 9 0 5 4 5 3 4 2 3 3 2 2 3 4 0 3 0 4 10 3 4 4 2 15 1 0 0 9 14 3 37 15 0 10 2 21 8 1 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG2212(Multisubunit Na+/H+ antiporter, MnhF subunit) 9 8 5 6 1 5 7 0 2 2 5 4 3 4 0 1 4 1 5 2 1 3 11 6 10 0 9 5 4 1 4 5 3 0 8 13 10 62 5 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG13041() 4 6 7 10 7 0 13 2 2 0 0 2 4 2 2 1 3 2 4 6 3 8 3 5 6 4 1 7 0 0 3 11 15 8 33 18 4 17 2 9 5 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG22697() 4 1 6 4 0 2 0 5 2 2 3 0 2 4 0 7 3 12 5 1 4 0 5 4 0 93 1 3 1 1 2 2 9 4 13 8 1 22 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3709(Uncharacterized component of phosphonate metabolism) 14 10 5 16 3 12 18 1 1 0 0 0 0 0 0 1 0 0 1 3 4 6 8 6 3 1 0 1 0 0 0 0 0 0 0 0 0 127 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3911(Predicted ATPase) 45 2 2 3 7 0 5 4 6 1 5 5 0 0 1 4 3 4 3 3 3 3 7 2 6 1 1 10 2 0 3 9 7 6 34 21 7 1 5 10 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3522(Uncharacterized protein conserved in bacteria) 142 1 1 0 0 1 1 0 0 0 0 0 4 2 0 0 2 0 1 3 0 0 7 0 0 0 1 4 1 0 4 1 0 0 2 2 2 57 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08453() 16 4 0 15 2 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 13 9 25 10 11 2 1 4 14 11 16 16 0 4 4 0 0 31 20 4 0 2 0 0 0 0 0 0 0 0 0 4 0 0 1 0 NOG38613() 25 1 5 15 3 5 0 0 0 0 0 0 0 0 0 0 0 0 0 4 14 11 32 9 17 0 0 4 4 12 3 18 2 2 6 0 0 26 16 3 0 3 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG29985() 20 20 9 20 2 7 11 2 4 8 0 5 0 7 1 5 0 0 5 4 20 4 14 10 2 0 8 1 3 2 3 10 4 0 9 3 0 0 12 1 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG38999() 5 12 19 24 2 2 0 5 0 0 0 3 1 8 4 5 5 2 4 9 7 6 7 3 3 18 2 1 3 0 4 5 5 6 10 37 2 0 7 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12510() 5 5 8 5 0 0 7 2 2 0 0 2 3 4 0 6 5 0 2 4 2 1 9 3 3 3 2 5 0 2 0 15 10 4 18 37 1 32 4 15 2 6 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG1141(Ferredoxin) 18 4 3 14 2 1 1 0 0 1 0 0 0 0 2 0 0 0 0 0 12 4 17 11 9 1 2 5 12 16 16 12 3 0 6 4 1 19 21 3 0 13 0 0 0 0 0 0 0 0 0 8 0 0 0 0 NOG23231() 3 2 13 4 14 1 7 5 4 1 3 3 6 5 3 2 0 0 4 8 6 10 8 2 12 0 3 4 3 0 1 12 10 0 37 9 3 1 2 15 3 5 0 0 0 0 0 0 0 0 0 5 0 0 0 2 NOG07807() 2 3 0 2 0 2 0 3 4 0 0 1 9 6 5 4 0 0 5 2 4 1 4 0 3 0 5 4 4 1 0 4 0 0 11 5 0 125 3 11 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG1739(Uncharacterized conserved protein) 83 4 5 4 1 1 0 1 6 5 4 1 3 10 11 6 1 10 4 4 2 1 1 2 0 7 2 0 1 2 1 2 0 0 1 11 21 17 0 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16669() 2 7 8 5 0 5 5 1 5 3 0 4 6 3 4 3 5 2 2 7 2 0 5 5 1 8 1 1 1 1 2 9 9 7 29 22 1 18 1 9 3 17 0 0 0 0 0 0 0 0 0 7 0 0 0 5 COG4667(Predicted esterase of the alpha-beta hydrolase superfamily) 71 18 10 8 2 0 1 2 4 5 0 3 0 5 2 2 0 0 4 3 0 3 6 2 10 1 0 6 4 0 6 4 2 0 13 11 7 4 1 8 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG25487() 8 8 15 11 0 6 0 0 0 0 2 0 1 16 2 4 4 6 9 4 12 11 5 2 4 14 4 8 2 6 0 2 2 0 4 6 0 56 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3758(Uncharacterized protein conserved in bacteria) 205 0 0 0 1 0 0 0 1 0 0 0 0 1 2 1 3 7 4 0 0 0 0 0 0 11 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3392(Adenine-specific DNA methylase) 7 7 3 2 2 0 2 10 14 2 3 5 1 1 6 5 13 12 3 7 0 2 4 4 1 24 2 5 5 2 9 3 7 5 6 14 9 11 1 6 7 3 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG39439() 237 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3749(Uncharacterized protein conserved in bacteria) 82 0 1 3 1 2 1 4 6 0 8 4 1 9 3 1 10 7 9 5 0 0 3 0 1 4 7 0 1 0 4 0 0 3 6 10 12 29 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG10778() 19 9 1 13 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 3 16 6 20 14 14 3 1 9 7 15 12 11 3 1 8 18 0 12 11 9 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09473() 28 8 3 17 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 2 16 7 21 16 11 1 0 4 7 13 18 12 2 3 0 0 0 14 18 1 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG2145(Hydroxyethylthiazole kinase, sugar kinase family) 49 3 3 4 2 5 3 1 0 0 1 0 1 0 0 2 0 4 2 5 3 4 6 3 3 0 0 5 3 2 6 3 2 8 6 2 2 76 6 1 0 6 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG1712(Predicted dinucleotide-utilizing enzyme) 44 13 14 9 1 2 1 2 1 0 0 0 0 17 9 4 4 0 3 4 7 7 5 3 1 18 4 4 4 0 3 6 1 1 6 16 15 3 0 4 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 NOG25206(C4-Dicarboxylate transporter protein) 7 5 5 11 0 4 1 5 2 1 0 0 0 11 3 0 0 1 10 6 5 9 5 4 2 0 1 7 1 0 4 6 6 2 11 9 10 47 10 6 0 7 0 0 0 0 0 0 0 0 0 5 0 0 0 10 COG2921(Uncharacterized conserved protein) 59 7 5 3 2 0 1 3 2 6 6 1 1 3 0 7 14 6 8 2 0 1 4 1 0 7 4 2 0 0 0 0 1 4 0 10 3 64 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11936(Hydroxyneurosporene synthase) 4 2 0 0 0 0 1 3 0 3 6 0 2 13 2 1 2 7 7 0 2 3 1 2 4 2 3 5 3 1 2 6 6 8 21 3 0 92 4 10 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3261(Ni,Fe-hydrogenase III large subunit) 67 9 10 11 0 0 0 2 1 0 0 3 2 15 5 6 20 4 8 0 5 9 0 3 2 4 0 1 3 0 1 2 1 2 0 8 7 25 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG04487(Cytidine monophosphate-N-acetylneuraminic acid hydroxylase) 7 13 12 15 0 1 2 2 1 2 2 4 2 4 2 2 6 6 1 2 5 6 10 10 4 24 4 10 0 0 2 7 4 8 16 16 4 3 4 1 3 4 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG1394(Archaeal/vacuolar-type H+-ATPase subunit D) 2 6 22 7 0 1 1 0 0 2 0 1 0 4 0 2 0 0 0 6 4 11 6 5 2 10 3 4 2 6 0 7 12 3 0 8 21 47 2 4 7 11 0 0 0 0 0 0 0 0 0 1 0 0 0 8 NOG05981(Protein involved in purine metabolism) 5 3 2 4 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 7 6 4 0 3 8 4 0 5 3 3 0 2 1 0 152 1 6 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG26114() 4 4 3 0 19 1 12 6 1 0 0 2 6 0 4 1 4 2 1 2 7 7 10 2 4 0 1 1 1 2 0 14 12 14 34 15 1 4 5 12 3 8 0 0 0 0 0 0 0 0 0 1 0 0 0 7 COG5021(Ubiquitin-protein ligase) 56 7 28 10 13 17 0 4 0 3 0 0 0 3 2 2 4 4 6 2 0 2 5 3 0 0 1 1 0 22 0 4 9 0 0 6 0 7 1 6 7 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG10565() 0 0 2 0 0 0 0 0 1 0 2 0 2 3 0 0 11 25 5 1 0 0 3 0 0 42 0 0 0 0 0 0 2 2 0 2 0 134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06532(RND superfamily protein) 129 7 10 6 3 0 1 0 0 0 0 0 0 12 0 4 3 0 6 0 1 0 5 2 0 0 2 0 1 0 1 12 2 8 5 2 0 4 0 4 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG1547(Uncharacterized conserved protein) 14 6 26 13 0 2 0 2 0 1 0 0 0 0 2 0 0 1 0 5 15 1 18 12 13 11 1 4 9 6 8 8 3 0 2 7 0 23 15 4 0 0 0 0 1 0 0 0 0 0 0 3 0 0 0 1 COG5587(Uncharacterized conserved protein) 43 4 3 4 2 0 11 0 2 1 3 4 2 4 1 7 3 10 5 0 0 1 7 2 0 1 0 3 0 0 4 13 10 3 15 7 5 36 0 10 5 3 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG4287(PhoPQ-activated pathogenicity-related protein) 5 11 23 9 4 3 3 2 3 3 0 2 2 6 2 1 2 0 3 6 8 3 12 4 2 5 10 3 2 0 0 3 12 6 12 27 11 5 5 9 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG5316(Uncharacterized conserved protein) 1 13 58 7 0 0 0 0 0 0 0 0 0 2 7 2 8 0 5 4 3 12 4 4 3 6 1 3 7 0 1 5 2 2 5 8 9 49 1 0 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3275(Putative regulator of cell autolysis) 83 8 3 2 0 0 0 1 1 5 2 5 2 1 2 0 0 2 10 2 0 2 1 1 0 11 0 0 2 2 2 1 1 4 8 8 8 46 4 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG08481() 22 9 2 9 0 2 0 1 0 0 0 0 0 2 0 0 0 0 0 1 18 7 27 14 18 0 1 3 6 17 12 12 0 0 2 2 0 27 17 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 COG3257(Uncharacterized protein, possibly involved in glyoxylate utilization) 60 4 1 1 0 4 2 2 3 2 4 0 3 14 3 1 0 0 7 6 1 2 3 3 1 0 11 0 2 0 6 8 9 4 14 5 4 23 10 5 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG14440() 5 6 3 6 7 0 7 3 2 2 2 2 1 2 2 0 3 8 0 2 5 4 6 2 7 0 4 8 1 0 2 10 3 17 30 27 4 0 3 26 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG3675(Predicted lipase) 5 4 4 5 1 1 5 18 7 6 13 5 5 2 4 5 4 8 3 5 2 3 7 9 3 6 4 3 5 7 8 7 8 2 4 20 2 12 2 4 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG24132(Copper resistance protein) 161 2 0 0 0 3 1 2 3 5 0 0 1 8 2 0 0 0 1 2 6 1 0 0 6 0 5 2 0 0 2 3 0 2 4 6 1 1 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG14658() 21 9 4 15 0 4 1 2 1 2 0 0 2 0 0 0 0 0 0 1 13 6 13 13 6 0 1 7 4 7 17 18 2 2 4 10 0 26 13 3 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG11519() 47 12 7 9 3 4 5 21 1 5 1 4 3 5 12 3 5 0 6 4 1 3 2 5 4 0 0 1 1 1 4 10 6 0 13 8 0 4 4 3 1 6 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09467() 66 2 38 7 1 1 1 7 1 1 4 1 2 6 0 0 0 0 0 3 3 14 1 3 5 6 2 6 3 0 1 4 1 2 7 8 0 12 0 8 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG1467(Eukaryotic-type DNA primase, catalytic (small) subunit) 3 6 18 5 0 3 0 0 3 3 0 6 5 4 8 1 0 1 2 8 0 9 13 7 6 29 8 4 1 9 0 7 16 2 2 21 2 0 3 2 6 4 0 0 0 0 0 0 0 0 0 3 0 0 0 5 NOG27740() 24 3 0 12 5 2 2 0 0 0 0 0 0 0 0 1 0 0 0 0 12 1 12 12 14 0 0 8 6 19 22 9 4 2 8 2 0 33 14 4 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG3428(Predicted membrane protein) 3 7 1 0 3 1 2 0 0 0 1 1 0 3 0 0 2 4 1 0 0 0 3 1 0 0 1 0 3 1 5 4 0 4 6 2 1 164 2 1 1 2 0 0 0 0 0 0 0 0 0 2 0 0 1 1 NOG19110() 3 5 2 1 8 0 12 1 5 2 6 0 0 3 4 1 2 4 3 2 3 4 8 2 2 1 6 0 8 2 4 14 14 8 41 26 0 4 1 9 5 5 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3424(Predicted naringenin-chalcone synthase) 5 1 2 2 4 8 6 3 2 0 0 0 1 4 0 0 2 2 7 0 0 0 1 4 2 0 5 1 3 1 0 4 5 0 6 5 3 139 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18569() 32 5 21 7 10 2 7 0 2 2 4 4 9 13 2 3 0 0 1 2 1 3 5 2 1 1 1 2 2 0 0 9 10 9 28 14 2 0 2 9 2 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1105(Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)) 54 0 1 0 1 0 0 0 1 3 1 0 0 6 1 0 6 9 9 0 1 0 0 0 0 10 0 0 0 0 0 1 0 0 0 0 4 122 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4669(Type III secretory pathway, lipoprotein EscJ) 44 0 0 1 0 0 0 7 0 2 0 1 0 0 0 2 0 0 0 0 1 0 0 1 2 7 2 0 0 0 0 0 1 0 6 2 2 140 6 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23400() 0 3 6 3 4 0 3 4 9 1 1 3 0 0 0 0 0 1 7 1 3 8 8 5 4 1 5 9 6 0 2 7 7 17 35 15 3 6 8 14 6 12 0 0 0 0 0 0 0 0 0 2 1 0 0 2 COG3255(Putative sterol carrier protein) 12 4 18 10 0 2 6 3 2 5 2 2 3 5 0 0 3 0 1 3 1 4 8 5 11 0 2 6 4 0 4 5 3 5 17 20 6 11 6 16 3 4 0 0 0 0 0 0 0 0 0 6 0 0 0 4 NOG30036() 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 1 11 22 2 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 0 0 166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25702() 229 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14526() 0 7 18 5 0 0 0 0 4 0 5 0 0 3 2 0 22 35 0 1 0 3 1 1 5 55 0 2 0 0 0 1 6 2 3 6 1 31 0 8 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4650(Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain) 136 4 5 2 0 0 1 4 6 0 0 0 0 1 0 1 2 1 4 2 1 1 1 3 1 0 8 2 3 0 2 4 1 4 8 4 2 7 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG4659(Predicted NADH:ubiquinone oxidoreductase, subunit RnfG) 38 1 0 2 0 0 1 1 3 4 3 1 0 2 0 4 7 5 7 2 0 0 2 4 5 1 2 1 0 1 1 3 0 2 0 5 5 117 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2161(Antitoxin of toxin-antitoxin stability system) 47 4 2 0 0 2 1 1 1 0 2 0 0 5 0 0 9 3 3 0 0 0 0 0 0 7 3 0 0 0 0 4 0 0 0 0 14 122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3287(Uncharacterized conserved protein) 120 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 1 0 2 0 2 1 0 4 1 0 0 0 4 0 0 0 0 0 37 47 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10824(Protein involved in oxidative phosphorylation) 14 7 2 15 2 5 0 0 0 0 0 0 0 0 0 0 0 0 1 4 16 3 34 12 10 0 5 8 8 8 16 5 1 1 5 1 0 27 14 2 0 0 0 0 0 0 0 0 0 0 0 3 1 1 0 0 NOG21415() 0 6 6 5 1 1 1 6 0 0 17 0 0 0 0 1 0 2 4 0 4 7 3 3 2 6 1 3 6 11 4 1 2 2 0 0 0 120 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2107(Predicted periplasmic solute-binding protein) 4 9 19 9 0 0 1 0 0 0 0 1 0 2 8 3 1 3 1 6 4 12 10 8 2 31 4 6 1 1 0 3 8 5 2 16 5 20 6 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 12 COG3642(Mn2+-dependent serine/threonine protein kinase) 1 12 28 5 1 0 0 0 0 0 0 2 2 6 4 0 1 2 0 4 7 7 3 7 0 12 3 4 4 5 0 7 7 8 2 11 15 39 4 3 6 3 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG07686() 15 4 1 11 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 19 10 21 13 21 1 1 2 8 15 9 10 2 0 2 0 1 20 29 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG17126() 44 12 11 22 0 1 1 5 0 3 0 0 4 1 6 3 0 2 1 4 7 6 12 8 2 1 1 9 0 0 2 5 7 2 16 5 9 4 3 3 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG12971() 19 4 0 20 1 2 2 2 0 0 0 0 0 0 0 0 0 0 0 2 14 5 24 20 10 0 4 5 10 14 13 16 2 0 9 0 0 19 10 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG22972() 0 6 16 6 0 1 1 28 1 4 11 0 7 4 3 8 2 3 12 2 1 0 5 2 4 4 2 1 4 12 1 3 8 0 2 9 1 45 1 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG04719() 67 3 3 7 2 3 3 3 4 0 0 4 0 3 0 3 2 5 5 1 0 0 3 1 5 10 2 0 3 3 0 11 1 5 0 7 1 44 9 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14990(Photosynthetic complex assembly protein) 5 2 4 4 0 1 2 2 2 3 1 0 6 4 2 3 1 0 8 9 1 1 3 1 3 6 4 3 2 0 0 14 3 4 15 13 1 66 5 12 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 7 NOG28294() 13 7 0 13 3 4 1 0 0 2 0 0 0 0 0 0 0 0 0 4 16 8 24 9 12 0 3 2 4 13 9 8 2 4 7 0 1 31 18 2 3 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG09313() 0 1 8 3 0 0 0 0 0 0 0 0 0 0 0 0 27 25 1 1 4 3 5 1 0 96 2 0 1 0 0 0 0 0 0 13 0 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10848() 19 4 0 9 1 3 1 0 0 0 0 0 1 0 0 0 0 0 0 2 20 11 16 11 24 0 2 8 15 17 15 3 3 0 0 0 0 27 12 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG11943() 1 2 3 1 1 2 6 10 11 0 1 0 5 4 11 5 5 5 5 3 6 2 7 0 0 4 2 3 0 0 0 15 13 4 20 19 6 36 6 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG10106(Decaheme cytochrome c protein) 225 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18277() 55 5 15 5 1 0 3 0 0 2 11 0 0 1 0 0 2 0 1 1 7 2 12 1 5 2 2 3 1 0 4 8 5 4 27 12 2 6 5 4 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG5032(Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family) 0 4 25 13 15 29 3 5 0 3 0 1 0 3 2 6 1 2 13 1 4 4 5 2 2 0 0 2 0 29 6 12 0 2 2 12 0 12 4 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG07963() 1 5 5 6 10 2 8 2 2 4 3 5 2 0 0 2 1 0 0 4 5 8 4 1 3 0 9 5 3 0 2 9 11 9 32 21 1 5 4 14 3 6 1 0 0 0 0 0 0 0 0 1 0 0 0 9 NOG13746(Protein Rv0883c) 0 0 0 0 0 0 0 0 0 0 1 0 0 4 2 0 19 21 8 1 0 0 0 0 0 49 0 0 0 0 0 1 0 2 0 0 0 119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2861(Uncharacterized protein conserved in bacteria) 34 13 36 3 0 0 0 0 1 3 0 0 2 2 6 1 1 0 1 0 12 6 8 4 1 20 3 9 1 0 0 5 0 4 0 10 11 24 1 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG5540(RING-finger-containing ubiquitin ligase) 115 3 4 3 4 10 3 4 0 2 2 1 0 1 9 5 6 2 2 1 4 2 1 1 6 3 2 3 0 6 2 2 2 0 0 9 2 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG12923(30S ribosomal protein) 13 7 2 16 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 20 5 20 12 21 0 1 8 12 9 11 4 1 0 2 4 0 23 27 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG15830() 3 1 6 5 0 1 2 2 0 0 0 4 1 3 2 3 3 11 1 3 6 5 19 7 9 30 7 4 4 0 2 6 5 3 5 26 4 0 4 3 7 2 0 0 0 0 0 0 0 0 0 5 0 0 0 13 NOG15303(Carbohydrate kinase) 14 4 2 18 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 1 19 8 18 12 13 2 2 7 10 12 15 14 2 1 7 4 0 12 14 4 1 0 0 0 0 1 0 0 0 0 0 3 0 0 0 1 COG0374(Ni,Fe-hydrogenase I large subunit) 72 4 1 0 1 0 0 2 0 0 0 0 0 4 0 0 0 0 2 0 0 0 4 0 0 0 1 2 0 2 0 0 0 0 0 0 1 131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04733(Phycobilisome linker polypeptide) 19 3 0 3 3 5 0 0 0 0 0 0 2 0 0 0 0 0 0 2 5 0 0 0 0 3 0 2 0 2 0 14 2 0 4 2 0 114 37 3 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG21679() 1 0 3 2 0 0 0 16 6 2 3 1 7 3 0 1 8 4 3 6 3 7 3 1 3 38 4 6 3 4 4 6 5 2 10 18 0 6 12 0 3 0 0 0 0 0 0 0 0 0 0 5 0 0 0 17 COG3017(Outer membrane lipoprotein involved in outer membrane biogenesis) 56 5 5 0 1 1 0 6 0 0 2 0 2 10 4 0 5 15 2 2 0 1 4 0 0 5 2 0 2 0 4 1 3 0 0 3 16 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1563(Predicted subunit of the Multisubunit Na+/H+ antiporter) 11 5 9 11 3 0 7 0 3 0 2 1 0 3 4 3 2 2 0 7 2 3 7 6 5 0 7 3 6 0 4 7 1 4 18 10 36 17 6 2 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG4821(Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain) 11 8 20 12 0 0 4 1 2 0 0 0 0 0 2 1 6 4 1 3 1 0 5 2 0 27 3 4 4 0 2 9 9 5 13 27 3 18 3 4 4 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG3440(Predicted restriction endonuclease) 2 2 7 13 1 2 1 2 1 6 2 2 5 5 2 0 2 1 5 0 4 0 10 3 3 14 1 1 4 0 2 2 4 8 8 6 7 73 2 2 0 2 2 0 0 0 0 0 0 0 0 1 0 0 0 6 COG4636(Uncharacterized protein conserved in cyanobacteria) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 9 212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14561() 16 12 5 20 3 19 16 1 1 0 0 0 1 1 0 1 0 0 2 1 3 5 12 6 11 2 0 0 1 2 0 1 0 0 0 0 0 82 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4360(ATP adenylyltransferase (5,5-P-1,P-4-tetraphosphate phosphorylase II)) 24 4 1 11 1 5 3 0 0 2 0 0 0 0 0 0 0 0 0 1 20 7 20 13 22 0 0 0 12 7 16 8 1 0 2 2 0 16 17 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG1556(Uncharacterized conserved protein) 123 5 4 4 0 0 0 2 0 1 0 0 0 1 0 1 0 0 0 1 3 1 3 2 1 11 0 0 0 0 0 0 0 0 0 4 4 52 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5011(Uncharacterized protein conserved in bacteria) 10 0 0 3 1 0 2 0 0 0 0 0 0 3 0 0 1 3 0 0 0 0 0 1 0 2 3 2 0 1 2 15 2 2 0 7 2 133 24 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG14009() 3 6 9 7 0 0 1 1 7 1 4 4 0 10 5 1 1 0 5 6 0 0 1 4 2 0 5 1 3 0 0 11 6 8 11 23 1 47 9 8 0 5 0 0 0 0 0 0 0 0 0 6 0 0 0 2 COG3012(Uncharacterized protein conserved in bacteria) 82 14 3 3 1 0 3 0 3 4 0 0 5 11 0 0 4 4 1 2 2 3 5 3 0 1 0 2 1 6 0 4 1 3 3 2 18 7 19 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG14469() 4 6 6 5 5 2 7 0 6 2 2 3 0 1 0 1 4 2 6 4 0 9 6 5 7 1 4 5 1 0 3 12 8 6 29 26 2 8 4 13 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG08933() 5 2 1 4 2 2 0 2 4 2 0 6 4 9 0 0 0 0 6 4 6 0 7 4 9 0 1 0 4 0 5 16 12 8 14 19 4 25 13 12 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG19091() 1 6 6 2 1 0 5 1 6 4 0 2 2 0 2 0 6 0 1 3 9 2 3 3 5 2 6 9 4 2 2 9 14 2 27 22 2 10 11 13 6 5 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG27351() 3 2 3 8 7 0 3 10 8 0 2 2 4 6 2 3 3 3 3 3 2 3 7 4 1 0 0 9 2 0 5 9 12 6 22 17 3 14 7 11 10 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1378(Predicted transcriptional regulators) 55 1 8 4 0 0 0 0 0 0 0 2 0 0 8 0 7 4 1 7 3 9 6 2 6 9 10 2 4 0 0 3 4 0 0 9 47 4 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 4 COG3358(Uncharacterized conserved protein) 2 1 4 0 0 1 0 2 3 0 3 0 0 0 0 1 5 3 7 0 8 3 7 9 5 1 6 11 3 0 5 5 4 7 7 10 0 86 3 5 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09454() 23 4 3 14 1 0 2 0 0 1 0 0 0 0 0 0 0 0 1 4 12 3 20 12 16 0 0 4 14 10 17 8 1 0 2 0 0 32 12 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 2 0 COG1288(Predicted membrane protein) 189 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 5 0 0 0 0 0 0 1 0 0 4 2 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12740() 136 4 3 2 4 0 0 3 1 0 1 0 0 9 0 1 0 1 0 0 2 0 2 0 0 0 3 2 3 1 0 3 0 4 0 2 3 27 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG37754() 19 3 1 11 2 2 1 0 0 1 0 0 0 0 0 0 0 0 0 4 34 6 13 14 10 1 0 0 8 15 9 7 3 2 4 2 0 22 18 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 1 NOG16032() 85 8 5 4 1 3 1 1 1 0 6 4 1 3 0 2 3 3 2 3 5 2 1 3 2 0 2 6 0 1 0 5 3 2 9 18 0 11 5 6 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG04779(Hydrolase, hydrolyzing O-glycosyl compounds) 7 6 4 5 11 27 0 0 0 0 0 0 0 2 0 0 0 14 6 0 5 0 8 1 1 2 4 0 0 27 0 3 0 4 0 4 0 67 13 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1658(Small primase-like proteins (Toprim domain)) 3 11 16 15 0 2 4 8 2 0 0 1 2 1 4 0 4 2 0 8 14 4 6 1 7 6 1 4 6 0 4 4 1 2 11 12 13 16 5 0 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 17 COG3704(Type IV secretory pathway, VirB6 components) 179 0 1 0 1 0 1 0 0 0 0 0 0 6 0 4 0 2 0 2 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 12 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG04951() 3 5 38 12 3 0 2 0 0 1 1 1 3 2 4 2 0 4 8 9 8 1 11 3 2 0 6 1 3 0 2 3 2 0 0 15 3 49 0 2 1 5 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG28567() 14 8 0 17 3 3 2 0 0 3 0 0 0 0 0 0 0 0 0 1 26 6 19 9 22 1 1 7 7 11 7 12 2 4 2 2 0 15 14 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG28616() 11 10 8 13 0 2 5 5 3 0 4 1 0 14 4 3 16 20 12 10 0 0 1 1 8 11 4 3 5 4 2 8 2 5 6 0 0 11 1 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG4589(Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase) 43 2 7 6 0 0 4 6 3 1 0 1 3 6 2 3 2 2 4 3 1 4 3 0 6 2 10 1 4 1 3 11 1 2 15 5 19 27 0 4 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG09449(NHL repeat protein) 4 3 4 2 0 0 0 4 0 2 3 8 2 14 5 7 4 3 1 4 9 1 7 5 2 9 4 6 3 0 6 2 8 2 0 17 3 35 2 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 24 NOG12776(Photosystem I protein) 28 7 1 9 3 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 19 3 15 10 12 0 2 3 13 15 9 13 0 2 2 1 0 29 10 2 0 4 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG29948() 12 11 12 22 0 3 0 0 0 0 0 0 0 0 2 0 0 0 1 0 23 9 28 10 22 4 1 3 8 8 20 4 2 2 4 4 0 0 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4969(Tfp pilus assembly protein, major pilin PilA) 57 3 11 3 0 0 0 0 0 1 2 2 6 7 0 3 6 2 3 2 2 3 0 1 0 3 5 1 1 0 2 0 2 0 0 2 14 71 0 2 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG14388(Sulfur oxidation protein) 10 7 9 10 0 2 1 7 2 5 0 3 1 6 0 0 2 0 3 3 3 0 6 7 11 0 7 4 3 0 9 7 11 8 12 9 0 30 5 7 1 2 0 0 0 0 0 0 0 0 0 3 0 0 0 5 NOG19135() 2 4 3 6 7 2 8 10 3 4 2 3 1 1 7 1 0 0 4 1 2 0 2 3 6 0 10 7 1 2 8 6 5 6 32 21 2 5 1 23 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3281(Uncharacterized protein, probably involved in trehalose biosynthesis) 128 0 0 0 1 0 0 0 0 0 0 0 0 2 2 1 0 3 1 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22440() 7 2 21 5 3 3 6 2 0 0 0 0 4 3 0 1 0 1 0 6 8 12 22 12 5 0 9 3 10 0 9 9 7 6 8 19 0 0 2 5 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG18818(Redox protein) 5 9 22 7 2 0 1 1 1 1 0 1 0 2 0 1 4 1 2 4 5 1 9 4 4 0 5 12 2 1 4 8 9 6 20 7 3 22 12 4 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 8 COG1774(Uncharacterized homolog of PSP1) 0 3 6 5 10 1 2 0 3 0 7 3 0 6 2 4 7 17 5 3 2 0 2 3 4 7 1 4 1 6 2 8 4 5 14 11 7 24 8 8 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG36028() 1 4 0 0 1 0 0 5 0 0 21 3 2 6 0 1 0 0 5 0 1 1 1 5 1 1 3 0 0 0 0 0 0 0 0 2 0 153 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3593(Predicted ATP-dependent endonuclease of the OLD family) 186 5 0 0 0 0 0 0 0 0 0 0 0 2 2 0 2 2 0 0 0 2 0 0 0 1 3 0 1 0 2 0 0 0 0 0 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 NOG14471() 3 5 4 5 7 1 4 0 5 2 2 5 2 0 4 1 0 1 1 0 3 7 8 5 7 1 7 5 0 0 1 6 8 11 36 19 4 14 3 11 4 0 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG09456(Transcriptional regulator, Crp/Fnr protein) 9 2 3 7 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 16 16 16 19 0 1 3 14 9 7 18 2 2 4 0 0 26 8 1 1 3 0 0 1 0 0 0 0 0 0 3 0 0 2 0 COG3750(Uncharacterized protein conserved in bacteria) 4 0 4 2 1 1 2 5 0 3 3 2 4 10 2 0 0 2 11 4 2 1 3 4 2 1 7 4 8 0 6 7 4 2 7 14 3 56 2 15 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG13679(Ribosomal protein) 3 6 6 2 8 1 8 0 6 1 8 5 2 2 6 1 2 3 1 6 2 3 5 7 1 3 8 7 6 1 4 11 5 7 22 21 0 5 6 11 5 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG09079() 18 2 2 13 5 5 0 3 0 0 0 0 0 0 0 0 0 0 1 3 20 7 18 15 23 0 1 2 6 7 6 4 0 0 2 0 0 24 30 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2036(Histones H3 and H4) 3 8 19 6 13 14 2 7 5 5 0 0 4 14 9 7 3 5 1 2 7 0 4 1 0 2 2 2 1 11 0 0 0 1 2 11 4 26 0 3 8 3 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1553(Uncharacterized conserved protein involved in intracellular sulfur reduction) 62 9 6 3 0 1 0 1 0 0 1 0 0 0 0 3 3 0 3 4 7 2 5 1 2 0 1 2 0 1 0 3 8 0 8 12 6 58 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29199() 2 5 6 2 4 1 10 0 3 2 2 4 0 8 2 4 5 5 0 2 2 7 6 1 5 4 5 2 3 2 4 6 8 4 29 22 1 8 2 17 3 5 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG14982() 58 3 2 1 2 2 1 6 2 1 1 2 1 13 2 3 7 6 7 4 6 4 3 0 2 13 9 2 2 3 3 2 3 0 4 22 3 1 0 2 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG16505() 122 7 8 5 1 0 3 1 0 1 0 1 1 5 2 1 4 1 6 7 1 2 3 6 4 1 2 2 3 0 1 2 0 0 0 1 5 3 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG32710() 12 3 0 13 2 4 0 4 0 0 0 0 2 2 0 0 0 0 0 3 26 17 29 11 14 2 1 6 15 11 11 7 1 0 3 0 0 0 9 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 7 COG4539(Predicted membrane protein) 80 8 21 2 0 1 1 0 1 0 0 2 1 0 2 1 3 0 1 2 1 1 5 1 2 16 6 3 1 1 1 2 4 4 2 15 0 16 3 4 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3147(Uncharacterized protein conserved in bacteria) 143 1 7 1 1 0 0 0 0 1 0 0 1 5 2 1 4 5 2 0 0 0 0 0 0 10 2 0 0 0 2 0 3 0 2 0 4 15 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33160() 11 0 0 3 1 0 3 0 0 0 2 0 0 8 2 1 6 8 2 2 0 0 0 1 0 28 3 0 0 0 0 7 0 1 6 0 0 110 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06373() 15 1 17 8 1 7 0 5 2 1 5 1 0 19 5 7 10 0 9 1 4 1 9 8 5 4 7 1 8 2 0 2 6 6 6 2 2 7 1 7 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 13 COG1795(Uncharacterized conserved protein) 63 13 12 14 0 0 0 4 0 0 0 0 0 1 0 0 2 2 0 5 3 1 3 6 5 5 4 7 2 1 2 1 8 2 6 16 1 27 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5519(Superfamily II helicase and inactivated derivatives) 56 11 3 5 1 0 0 11 1 0 33 0 2 2 0 3 2 4 6 0 5 2 4 0 3 1 4 2 1 1 0 2 0 0 0 0 2 49 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG26551() 211 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5635(Predicted NTPase (NACHT family)) 8 7 13 9 3 3 1 0 0 2 0 4 0 1 0 1 0 0 2 2 12 5 24 15 17 0 2 3 6 10 12 2 0 0 0 4 6 41 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08942(Transposition protein) 199 3 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 0 0 1 2 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24928() 6 5 5 2 11 0 5 2 1 4 1 1 2 3 0 4 4 2 4 4 2 1 5 3 2 0 4 3 4 0 2 16 7 6 37 21 1 0 11 9 7 1 0 0 0 0 0 1 0 0 0 1 0 0 0 6 NOG12996() 14 8 2 17 1 5 2 0 0 0 0 0 0 0 0 0 0 0 0 3 21 9 14 17 21 1 2 3 15 7 16 5 1 4 3 10 2 5 3 2 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG13763() 0 0 0 0 0 0 0 3 0 0 1 0 0 0 0 0 14 35 3 0 0 0 0 0 0 55 0 0 0 0 0 0 0 0 2 0 0 103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2746(Aminoglycoside N3-acetyltransferase) 3 5 10 9 0 0 3 8 1 0 3 0 3 0 6 4 4 3 1 1 2 5 4 4 4 9 7 4 6 0 2 9 4 13 17 18 5 14 3 11 3 4 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3315(O-Methyltransferase involved in polyketide biosynthesis) 66 8 12 4 0 1 4 0 4 0 3 1 6 2 0 0 0 0 8 7 4 6 1 2 2 1 0 2 2 1 2 6 4 5 2 18 2 15 1 7 2 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG07996(Dihydroneopterin aldolase) 3 5 4 2 0 0 1 0 1 0 8 0 3 14 0 2 1 4 3 6 5 1 9 4 1 0 7 5 3 0 0 7 12 5 19 20 6 21 8 10 5 3 0 0 1 0 0 0 0 0 0 3 0 0 0 4 NOG12505() 0 0 0 0 0 0 0 1 1 0 0 0 2 0 0 0 20 25 1 0 0 0 0 0 2 70 0 2 1 0 0 0 0 0 0 0 2 88 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG18105(Heparinase III protein) 9 6 10 8 1 0 8 1 0 0 0 2 0 0 2 2 1 0 0 7 4 10 13 4 6 0 13 4 3 0 8 5 2 7 17 11 6 8 9 8 5 7 0 0 0 0 0 0 0 0 0 3 0 0 0 5 NOG16552() 28 5 0 12 1 4 3 0 0 0 0 0 0 0 0 0 0 0 0 4 9 10 12 7 8 0 1 6 14 11 13 12 5 0 2 0 0 23 16 1 0 0 0 0 0 0 2 0 0 0 0 6 0 0 0 0 COG3376(High-affinity nickel permease) 139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 6 0 2 0 0 1 0 0 55 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16705() 3 7 43 6 0 3 0 3 3 1 0 1 3 6 5 7 0 0 1 8 7 4 12 5 5 2 1 1 2 0 0 5 4 2 2 19 2 19 3 14 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12786() 19 5 0 10 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 1 12 9 20 17 13 0 1 3 9 12 11 16 1 2 4 0 0 22 14 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 4 COG3837(Uncharacterized conserved protein, contains double-stranded beta-helix domain) 93 1 1 2 2 4 2 0 2 2 0 0 7 3 2 1 4 0 5 0 1 1 0 1 4 1 2 2 3 0 0 1 0 2 2 1 7 50 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG5650(Predicted integral membrane protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39 41 1 0 0 0 0 2 0 61 0 0 1 0 0 0 0 0 0 0 0 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1701(Uncharacterized protein conserved in archaea) 0 5 16 4 0 0 0 0 0 0 0 1 1 10 10 3 0 0 0 4 5 9 10 6 6 7 6 7 4 4 3 9 8 10 2 18 6 2 9 7 3 7 0 0 2 0 0 0 0 0 0 2 0 1 0 7 COG3515(Uncharacterized protein conserved in bacteria) 142 6 0 1 0 1 0 2 0 0 0 0 0 5 0 0 2 0 2 0 0 1 0 1 0 0 3 0 0 0 1 0 0 0 8 4 2 32 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG22446() 6 8 13 11 0 1 4 5 3 2 0 1 1 7 2 1 7 3 0 5 3 4 5 3 4 7 4 6 3 0 2 4 10 4 14 24 3 1 9 11 2 3 0 0 0 0 0 0 0 0 0 1 0 0 0 7 NOG16065() 4 3 2 3 0 3 1 10 1 0 0 4 8 9 4 3 3 5 6 12 0 2 2 1 5 26 11 4 2 1 2 10 6 0 5 15 0 23 2 1 5 0 0 0 0 0 0 0 0 0 0 7 0 0 0 3 COG1537(Predicted RNA-binding proteins) 1 3 22 10 0 2 0 0 1 2 0 1 0 2 8 1 3 0 0 2 14 25 6 5 5 12 8 10 1 2 0 10 5 2 0 7 9 2 4 12 9 3 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG14483(Like protein) 60 10 9 4 3 3 0 4 1 1 7 0 2 13 3 2 2 2 4 0 2 1 7 2 5 0 5 0 1 1 2 5 5 3 9 3 0 21 1 4 0 0 0 0 0 0 0 0 0 3 0 2 0 0 0 2 COG4995(Uncharacterized protein conserved in bacteria) 32 3 1 3 13 7 1 2 2 0 0 0 0 0 2 0 0 6 6 0 1 2 1 2 1 32 0 0 0 3 0 4 0 0 0 9 0 71 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27269() 18 5 0 17 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 19 0 24 6 19 0 0 2 7 18 5 8 3 2 2 0 0 23 22 1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 2 NOG13932() 3 14 39 6 2 0 1 0 1 0 1 5 2 12 2 2 2 0 4 3 4 6 9 7 4 0 9 6 0 0 2 5 4 0 7 25 10 2 2 2 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG3265(Gluconate kinase) 39 5 3 5 2 2 5 8 3 2 0 4 0 5 4 3 5 5 4 6 2 1 3 2 2 4 5 6 2 0 2 6 10 2 12 10 1 15 2 5 4 0 0 0 0 0 0 0 0 0 0 3 0 0 0 5 NOG18192() 10 24 12 8 0 1 1 3 3 1 0 0 0 7 2 1 1 2 5 3 3 3 12 2 1 0 2 0 0 0 0 6 3 5 9 9 2 67 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26164() 11 3 7 4 19 2 8 9 3 10 4 2 4 4 0 3 2 7 4 2 0 2 1 1 1 1 1 6 5 4 0 9 3 2 16 1 0 31 7 9 1 2 0 0 0 0 0 1 0 0 0 0 0 0 0 1 NOG16602() 7 6 11 5 0 3 2 0 1 4 0 3 0 6 2 5 1 0 0 0 11 8 8 1 6 3 6 4 0 0 8 8 7 0 10 17 1 38 1 9 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG1743(Adenine-specific DNA methylase containing a Zn-ribbon) 0 1 1 1 0 1 0 0 0 0 0 0 0 5 4 0 4 9 2 2 8 0 1 0 0 30 1 0 9 3 0 0 0 0 5 8 2 107 6 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG37320() 14 7 2 11 3 0 1 4 0 0 0 0 0 0 0 0 0 0 0 1 11 6 21 10 8 0 3 8 15 10 14 4 0 3 6 0 0 32 13 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 1 2 COG3415(Transposase and inactivated derivatives) 35 6 5 1 1 0 0 5 4 2 0 1 0 9 0 0 8 0 4 0 0 0 0 0 0 10 0 0 0 1 0 0 0 0 0 2 20 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1527(Archaeal/vacuolar-type H+-ATPase subunit C) 4 8 27 8 1 1 0 0 0 0 0 0 0 6 6 1 1 0 0 3 5 5 6 7 0 13 6 8 7 3 2 3 8 4 0 14 11 9 2 5 8 8 0 0 0 0 0 0 0 0 0 2 0 0 0 11 NOG14780(Cytochrome protein) 9 5 4 6 1 4 1 5 9 4 0 1 2 16 2 1 1 0 6 4 1 2 10 7 10 0 5 3 6 1 3 0 2 2 9 2 22 38 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13489(Phage-Related protein) 0 2 2 3 0 2 4 36 1 3 23 0 4 1 0 0 1 0 10 0 2 4 2 3 9 0 7 1 0 10 3 4 5 3 0 10 9 35 2 0 0 2 0 0 0 0 0 0 0 0 2 5 0 0 0 3 COG2980(Rare lipoprotein B) 79 12 9 6 0 0 1 4 3 0 5 2 0 4 1 2 23 8 1 1 1 0 0 2 0 10 2 0 2 0 0 0 2 2 2 12 2 10 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5054(Mitochondrial sulfhydryl oxidase involved in the biogenesis of cytosolic Fe/S proteins) 0 0 8 4 3 1 5 13 0 0 3 4 2 6 2 1 16 15 5 7 3 2 16 3 7 11 5 1 2 2 2 2 4 6 2 27 4 7 5 1 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG5389(Uncharacterized protein conserved in bacteria) 6 10 13 8 0 1 2 2 1 2 2 1 2 11 0 0 0 0 3 7 2 3 14 5 5 0 4 1 1 1 4 10 9 7 13 20 2 19 5 7 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG17470() 2 4 1 6 0 1 4 7 1 1 3 2 5 2 2 4 9 9 2 5 8 1 14 7 1 30 5 5 13 4 0 5 9 4 12 11 0 1 2 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG17991() 31 7 2 3 2 0 0 8 1 3 7 0 2 5 4 1 0 0 1 5 1 3 6 0 0 3 4 2 1 0 0 5 6 1 8 3 3 64 6 6 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4260(Putative virion core protein (lumpy skin disease virus)) 111 1 4 0 1 0 0 0 2 0 2 0 0 3 2 0 2 0 2 0 1 1 2 0 3 2 0 1 4 1 1 7 1 4 4 2 8 29 3 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30008() 1 7 8 4 2 0 2 3 1 0 2 0 6 5 0 1 2 0 1 0 6 9 9 4 3 0 1 4 1 0 12 13 2 8 39 10 3 0 12 14 2 8 0 0 0 0 0 0 0 0 0 6 0 0 0 1 NOG13994() 5 10 13 8 5 1 3 6 3 3 2 1 2 6 2 3 1 0 8 7 8 3 3 2 5 2 1 5 2 1 2 7 3 3 12 32 10 0 2 11 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG5441(Uncharacterized conserved protein) 1 2 2 3 1 1 1 1 1 6 0 1 4 16 2 3 5 8 5 1 4 0 5 3 3 26 2 0 2 0 1 14 12 3 21 6 4 14 5 10 4 5 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG27256() 17 6 1 11 1 2 1 0 0 4 0 0 0 0 0 0 0 0 0 0 25 10 15 19 10 0 1 7 8 10 20 11 0 2 0 0 0 20 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06095() 39 7 12 3 0 0 4 0 2 4 1 4 0 5 4 4 2 5 1 4 8 4 6 4 0 5 5 1 1 0 3 3 10 6 7 18 2 4 3 6 5 0 0 0 0 2 0 0 0 0 0 4 1 0 0 3 NOG14457() 2 4 4 9 8 1 4 5 8 2 2 2 3 3 2 1 1 2 10 4 1 2 6 2 6 2 9 3 1 2 4 11 10 4 25 10 1 7 2 13 3 4 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG3629(DNA-binding transcriptional activator of the SARP family) 81 3 3 1 0 2 1 0 0 0 2 0 0 1 2 0 0 3 4 0 0 2 3 2 0 1 0 2 0 0 0 1 2 0 0 2 3 85 2 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3339(Uncharacterized conserved protein) 46 1 2 10 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 5 21 10 14 3 1 3 9 9 12 4 1 2 2 1 0 23 9 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08885(4,5-Dihydroxyphthalate decarboxylase) 9 9 6 18 0 6 1 11 0 6 0 3 2 12 6 1 3 1 3 2 9 6 9 1 2 12 2 0 0 0 2 2 1 0 5 0 1 51 1 1 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG2179(Predicted hydrolase of the HAD superfamily) 20 4 4 15 2 5 1 0 0 0 0 0 0 0 0 0 0 0 1 3 15 9 17 15 6 0 3 1 8 7 12 8 2 3 4 6 2 23 12 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4262(Predicted spermidine synthase with an N-terminal membrane domain) 108 4 1 1 2 1 1 12 2 0 0 0 3 4 0 0 3 0 0 1 0 2 1 1 0 3 0 0 1 0 0 1 0 0 8 4 18 23 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 1 NOG11644() 1 0 3 4 9 0 5 9 6 2 8 1 2 7 0 2 4 6 2 1 0 3 5 0 7 0 3 6 3 0 3 14 8 8 28 16 0 8 5 6 7 4 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG0731(Fe-S oxidoreductases) 0 13 22 8 1 0 0 0 1 2 0 0 2 4 4 3 0 0 0 7 4 7 12 2 7 19 2 3 3 3 3 10 10 5 0 13 18 2 2 3 4 2 0 0 0 0 0 0 0 0 0 6 0 0 0 4 NOG16664() 7 6 7 5 0 2 4 2 2 2 1 4 5 8 0 7 0 3 5 7 3 7 3 5 5 4 6 8 4 2 0 4 6 4 13 14 0 30 3 7 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG1683(Uncharacterized conserved protein) 123 3 6 1 0 0 0 0 0 0 0 2 1 7 4 1 3 0 4 0 1 0 4 0 2 5 1 7 0 0 0 0 2 4 2 2 21 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG07808(Permease of the major facilitator) 1 8 2 2 1 1 2 0 2 0 0 0 4 4 3 1 2 0 4 10 3 0 5 1 8 0 11 1 3 1 1 6 4 6 21 10 1 68 2 3 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 5 NOG10799() 17 4 2 15 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 2 23 7 13 10 13 0 0 8 11 20 7 3 2 2 0 0 0 20 19 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 1 NOG18940() 8 12 7 4 2 2 1 2 1 2 1 1 0 9 4 1 2 0 2 6 1 4 5 3 0 0 5 4 2 0 5 9 11 5 16 11 5 31 7 4 2 3 0 0 0 0 0 0 0 0 0 1 0 0 0 10 COG1855(ATPase (PilT family)) 0 7 9 6 0 0 0 0 0 0 0 2 2 6 4 1 0 0 0 16 1 8 4 4 4 17 9 5 0 1 0 7 14 15 2 9 20 3 2 7 4 8 0 0 0 0 0 0 0 0 0 1 0 0 0 13 COG3556(Predicted membrane protein) 55 7 3 19 1 5 0 0 0 2 1 0 0 3 0 0 0 1 0 0 14 3 11 10 6 1 2 1 4 7 2 10 0 3 6 1 1 18 8 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG1263(Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific) 189 0 4 0 0 0 0 0 0 0 0 0 0 2 2 0 1 0 1 0 0 0 0 0 0 5 2 0 0 0 0 0 0 0 0 0 3 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21442() 23 3 2 18 1 1 1 0 0 0 0 0 2 0 0 0 0 0 1 0 6 7 17 7 20 1 4 2 7 14 11 11 1 3 8 0 0 14 17 2 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG08880() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 22 33 2 0 0 0 0 0 0 48 1 0 0 0 0 1 0 0 1 0 0 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18441() 1 9 12 7 1 3 3 20 1 2 3 2 2 4 8 6 2 7 18 7 2 2 4 7 8 3 4 0 2 4 5 9 6 0 4 2 4 17 4 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG0230(Ribosomal protein L34) 34 10 6 11 4 0 2 2 3 1 0 2 2 3 4 1 1 1 2 5 3 4 4 3 3 21 1 1 2 0 0 8 2 5 10 9 4 24 0 4 4 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3087(Cell division protein) 86 4 1 1 0 1 0 7 1 0 11 3 1 6 2 1 23 12 3 2 0 6 1 0 3 8 2 0 1 1 1 0 4 2 0 2 3 8 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11967() 9 1 5 5 1 0 0 4 3 0 1 1 5 7 5 1 3 4 3 6 1 2 2 3 3 0 4 3 3 0 2 8 5 3 12 9 1 39 9 18 4 6 0 0 0 0 0 0 0 0 0 3 0 0 0 6 COG4615(ABC-type siderophore export system, fused ATPase and permease components) 145 2 2 0 0 0 0 1 0 0 0 2 6 7 2 0 2 2 3 3 0 4 6 0 1 1 1 0 1 0 0 0 0 0 4 1 2 7 0 1 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3822(ABC-type sugar transport system, auxiliary component) 7 4 7 7 0 0 4 2 3 2 1 4 7 7 5 0 3 1 1 4 0 0 6 3 0 4 13 5 5 0 2 7 9 3 20 9 7 12 8 9 5 4 0 0 0 0 0 0 0 0 0 7 0 0 0 3 NOG14969() 134 1 1 0 0 1 1 8 1 2 0 0 0 2 4 0 0 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 49 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14294(Acetyltransferase) 8 3 7 7 6 0 3 3 1 0 1 0 0 7 2 4 1 11 3 3 6 6 10 2 5 19 1 2 3 0 0 5 6 3 26 15 3 12 2 6 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3298(Predicted 3-5 exonuclease related to the exonuclease domain of PolB) 46 9 25 16 3 1 2 2 2 2 2 2 5 4 2 3 13 2 4 6 0 0 3 1 2 15 0 2 1 1 0 1 1 0 0 7 7 14 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06502() 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 7 9 4 0 0 0 0 1 0 29 0 0 0 0 0 1 0 0 0 4 0 148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16534() 17 4 1 15 5 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 13 11 16 9 13 0 4 12 9 15 13 5 1 0 5 0 0 13 16 0 0 0 0 0 0 0 0 0 2 0 0 3 0 0 0 0 COG5488(Integral membrane protein) 48 5 4 9 2 2 2 0 0 1 1 1 2 3 2 0 3 6 1 9 3 3 10 3 3 6 1 3 3 1 2 4 6 2 6 2 0 25 5 5 0 6 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG19790() 10 16 9 16 0 1 2 6 0 0 0 1 0 0 4 2 1 3 2 3 11 2 9 3 3 0 4 1 2 1 9 3 6 2 16 29 5 15 3 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1801(Uncharacterized conserved protein) 115 4 1 0 1 2 2 0 0 0 0 1 0 3 0 1 0 2 2 1 0 2 2 0 0 5 0 2 1 0 0 2 1 0 2 0 6 46 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19381() 2 1 7 4 4 2 3 4 1 0 3 0 2 1 2 2 0 1 3 2 7 7 13 2 0 0 1 7 2 2 5 10 8 4 38 14 4 15 1 12 6 3 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG17943() 195 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3577(Predicted aspartyl protease) 10 12 4 6 1 0 1 0 0 2 0 2 1 13 4 0 7 4 7 0 4 1 5 2 4 1 1 0 1 4 2 4 5 4 14 17 9 48 1 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13308() 29 6 6 4 0 1 0 0 1 0 0 2 3 1 4 1 9 6 4 0 2 2 7 5 2 3 6 1 2 0 4 7 2 1 12 13 1 47 1 7 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG3220(Uncharacterized protein conserved in bacteria) 64 6 4 0 0 1 0 0 3 0 2 0 6 7 2 2 5 5 5 0 0 0 1 1 0 2 2 0 2 1 3 1 0 0 4 4 24 47 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG28900() 10 4 0 11 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 12 13 19 3 14 0 1 4 9 9 10 11 5 0 3 0 0 53 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3957(Phosphoketolase) 68 2 1 1 0 0 0 0 0 0 2 0 0 2 0 0 7 5 0 0 0 0 2 0 0 1 0 0 2 0 2 0 0 0 0 0 3 107 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG09451() 16 8 0 19 1 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 16 3 24 9 14 0 4 2 12 13 9 5 1 1 4 0 0 24 11 0 0 2 0 0 0 0 0 0 0 0 0 5 0 0 0 0 COG1370(Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit) 1 5 11 9 0 0 0 0 0 0 0 1 0 1 6 0 0 0 1 4 2 8 6 4 1 71 3 0 2 3 2 2 3 6 0 9 15 0 2 7 3 10 0 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG32798() 16 5 1 9 0 5 2 0 0 2 0 0 0 0 1 0 0 0 0 3 14 6 22 11 9 3 0 6 12 10 13 7 1 0 2 0 0 28 19 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4241(Predicted membrane protein) 9 6 4 16 2 5 0 1 0 0 0 0 0 0 0 0 2 0 0 1 15 3 14 15 17 0 2 4 12 10 11 7 1 0 4 1 0 25 17 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG38089() 5 9 13 8 1 3 4 2 12 0 2 0 6 5 2 2 9 5 6 5 11 2 6 5 7 1 3 3 6 3 3 2 9 12 6 23 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG2012(DNA-directed RNA polymerase, subunit H, RpoH/RPB5) 2 5 8 8 2 0 2 12 8 0 7 0 0 1 6 4 16 14 4 3 7 6 13 5 1 15 3 6 0 3 1 2 2 4 6 8 17 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16573() 14 4 0 10 1 3 1 0 0 0 0 0 1 0 0 0 0 0 0 2 7 3 15 10 12 0 2 8 6 9 14 6 2 2 6 0 0 35 22 3 1 0 0 0 0 0 0 0 0 0 0 7 0 0 0 1 COG5421(Transposase) 4 19 1 2 0 0 0 0 0 0 0 2 0 1 0 0 2 6 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 29 139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12560() 0 1 1 2 0 1 1 1 0 2 10 1 3 2 2 0 0 0 3 5 1 0 3 0 1 40 5 2 0 4 1 3 1 4 6 5 6 54 1 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 32 NOG23515() 199 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1307(Uncharacterized protein conserved in bacteria) 2 3 31 3 0 0 0 0 1 0 0 0 1 0 1 0 11 13 3 4 4 11 14 4 0 43 4 2 1 0 0 1 1 2 1 9 4 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16710(Biopolymer transport protein) 7 11 24 10 2 2 4 1 0 3 3 4 3 9 6 1 1 1 5 4 1 4 7 3 2 0 3 4 2 1 2 9 3 3 2 10 2 33 7 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3134(Predicted outer membrane lipoprotein) 163 0 0 0 1 0 1 0 1 0 2 2 0 0 0 3 2 6 14 1 0 0 1 1 1 2 0 0 0 0 0 1 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5485(Predicted ester cyclase) 47 3 8 2 1 0 3 2 4 0 4 2 0 2 0 0 3 4 0 2 2 3 2 5 1 23 4 3 3 0 1 6 5 4 18 17 2 0 2 7 5 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 COG3117(Uncharacterized protein conserved in bacteria) 89 10 6 1 0 0 0 0 2 0 3 3 0 5 0 4 9 19 7 0 0 2 1 2 5 5 1 1 1 1 0 0 1 0 0 9 12 3 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10055(Phycoerythrin class protein) 18 5 2 10 7 1 2 0 0 1 0 0 0 0 0 0 0 0 0 5 17 6 12 10 17 1 2 4 9 11 12 13 4 0 5 1 0 0 23 2 2 2 0 0 0 0 0 0 1 0 0 0 0 0 0 1 NOG04744(Phosphorylase kinase) 33 0 1 0 3 4 1 0 1 1 0 0 0 0 0 0 0 0 1 2 7 0 0 0 0 0 7 0 0 9 0 20 3 0 2 0 2 53 52 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 COG1093(Translation initiation factor 2, alpha subunit (eIF-2alpha)) 1 3 22 5 0 2 0 2 2 0 0 0 0 4 10 1 2 4 0 6 2 8 10 3 7 8 3 12 3 1 3 5 9 3 0 11 16 9 6 5 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG09812() 115 5 7 10 0 1 0 0 0 0 0 1 0 2 2 0 0 0 2 3 0 2 1 1 0 6 1 1 0 0 4 2 1 0 9 8 1 14 0 0 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3162(Predicted membrane protein) 81 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07229(Arsenite methyltransferase (EC 2.1.1.137) methyltransferase) 19 8 0 15 1 5 0 0 0 0 0 0 0 1 0 0 0 0 0 0 21 9 16 17 11 1 0 2 10 22 20 6 2 4 2 4 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG09438(Photosystem I assembly protein) 17 6 1 13 3 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 16 2 14 9 13 0 0 8 9 14 15 11 4 2 2 2 1 27 7 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG19124() 1 1 10 0 7 0 2 4 15 4 2 1 4 1 0 2 0 1 2 2 2 12 7 2 0 7 6 3 1 1 7 8 3 4 31 21 0 6 8 10 3 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 COG3503(Predicted membrane protein) 48 18 6 8 2 0 0 2 0 0 2 5 2 1 0 1 0 0 3 0 7 6 6 0 0 0 2 2 1 0 2 9 8 5 6 17 7 2 7 14 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG08712() 5 1 1 1 3 1 3 1 2 5 3 5 3 9 2 7 3 5 8 1 2 3 6 1 0 6 2 3 2 2 1 7 2 2 1 5 1 77 2 1 1 2 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG12897() 26 4 1 10 1 6 1 0 0 0 0 0 0 0 0 0 0 0 2 0 11 10 21 11 14 0 1 8 10 4 11 13 0 0 2 0 0 16 16 1 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG5226(mRNA capping enzyme, guanylyltransferase (alpha) subunit) 0 0 5 0 1 0 0 28 16 0 0 14 24 7 0 4 10 8 13 28 0 0 3 0 0 15 0 0 0 0 0 0 0 2 2 4 0 6 4 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG14846() 3 6 15 4 0 0 1 5 1 0 4 2 1 3 2 1 0 0 2 2 0 0 2 2 2 0 4 0 1 0 0 0 4 2 8 12 4 105 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3524(Capsule polysaccharide export protein) 81 7 5 1 2 2 0 0 0 0 3 3 0 3 4 1 6 2 4 0 4 0 2 0 0 4 0 0 0 3 0 3 0 0 1 2 0 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11204() 49 7 9 4 0 0 0 0 1 4 0 1 2 2 2 1 0 7 2 4 5 2 4 2 2 25 2 2 2 0 1 2 2 4 2 11 6 21 2 4 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG3585(Molybdopterin-binding protein) 188 0 4 0 1 0 1 0 0 0 0 0 0 3 0 0 2 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26885() 184 3 4 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06037(Gene transfer agent (GTA) orfg15 protein) 2 0 0 0 0 0 2 1 0 0 4 2 0 6 0 1 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 1 0 0 0 1 4 176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1916(Uncharacterized homolog of PrgY (pheromone shutdown protein)) 1 5 22 8 0 1 0 0 0 0 0 2 0 9 2 1 0 0 1 13 17 11 11 5 1 0 13 6 7 3 2 4 7 8 2 9 8 6 0 1 4 9 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG3031(Type II secretory pathway, component PulC) 59 10 5 3 0 0 1 2 3 0 0 0 6 9 6 0 0 0 7 1 7 1 3 3 5 0 6 4 3 1 4 6 1 0 11 1 9 11 2 7 0 3 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG4670(Acyl CoA:acetate/3-ketoacid CoA transferase) 11 5 8 9 2 5 6 4 1 0 3 0 0 6 0 0 9 0 1 0 5 5 13 10 8 9 13 4 2 2 2 4 4 3 3 6 0 32 1 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3157(Hemolysin-coregulated protein (uncharacterized)) 145 1 1 3 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 1 1 2 1 0 1 2 0 2 0 0 1 0 2 0 0 5 27 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12976() 20 6 5 16 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 13 2 13 11 12 0 4 3 8 8 10 12 5 4 2 2 0 21 13 1 0 1 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG13495() 0 5 1 1 2 3 3 18 3 18 13 1 4 13 6 3 5 3 19 0 3 4 1 1 0 4 10 0 0 2 0 6 6 2 3 2 4 25 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG10553() 1 4 4 6 0 0 1 2 0 0 0 1 1 3 0 7 7 14 3 9 6 1 6 5 5 26 4 1 5 0 0 3 8 6 10 19 2 18 1 1 3 2 0 0 0 0 0 0 0 0 0 2 0 0 2 4 COG3063(Tfp pilus assembly protein PilF) 46 9 6 6 2 0 2 4 0 2 4 2 4 3 6 2 17 3 9 1 1 0 3 2 1 0 3 0 1 0 0 1 0 2 2 10 14 32 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2716(Glycine cleavage system regulatory protein) 73 8 10 3 0 0 1 2 0 0 2 0 0 14 5 4 2 0 9 2 1 1 1 0 0 2 0 0 0 1 1 2 0 0 0 15 15 27 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14479(Plasmid replication protein) 190 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 2 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07673(Tocopherol cyclase) 2 1 28 3 0 1 3 5 1 1 3 7 0 0 8 1 0 1 0 2 5 5 5 4 0 6 11 10 3 3 1 5 2 4 30 4 0 24 3 1 4 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG27475() 4 13 29 10 6 2 6 0 1 1 0 3 2 7 4 2 0 0 3 3 5 6 14 8 6 1 3 7 5 1 2 3 6 6 2 18 0 5 2 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG1644(DNA-directed RNA polymerase, subunit N (RpoN/RPB10)) 2 4 8 4 1 0 0 0 3 0 1 2 1 7 5 5 4 2 3 8 7 4 11 7 3 10 5 6 4 2 6 4 11 5 2 11 13 1 1 4 6 10 0 0 0 0 0 0 0 0 0 2 0 0 0 7 COG5349(Uncharacterized protein conserved in bacteria) 6 6 3 8 1 2 1 6 2 4 3 3 0 17 2 2 2 0 3 4 1 1 7 2 4 1 1 4 3 2 5 2 6 0 7 7 4 56 2 2 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG3563(Capsule polysaccharide export protein) 101 5 1 0 2 1 0 5 4 0 0 0 0 3 0 1 0 3 8 0 2 0 1 0 0 0 0 2 1 5 2 2 0 0 0 0 1 40 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4672(Phage-related protein) 17 3 7 5 1 2 2 7 0 9 5 1 5 0 0 1 4 2 7 9 4 1 6 3 3 5 2 6 3 8 4 1 3 2 6 6 0 44 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG18827() 5 11 7 10 0 2 1 2 1 0 1 0 0 4 0 1 6 4 2 5 6 1 7 3 2 23 5 1 3 0 2 2 5 5 13 27 7 12 7 4 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG14528() 14 13 13 15 0 1 13 4 4 0 0 2 0 7 11 3 0 4 0 0 8 8 17 13 8 0 0 5 3 0 10 2 0 2 3 5 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG09073() 2 0 0 2 1 1 0 3 2 1 0 2 0 4 0 0 0 0 8 0 4 2 2 2 4 0 2 2 1 2 2 6 1 2 0 0 0 141 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16489() 0 3 2 2 0 0 0 11 6 7 0 10 6 0 0 0 2 0 0 2 8 4 6 3 2 0 13 2 5 0 2 3 1 2 9 4 2 78 0 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21807(Dna-Directed DNA polymerase) 10 8 21 14 2 5 4 8 2 0 4 0 0 3 9 2 0 0 7 1 0 2 3 5 6 0 3 5 2 1 4 6 7 3 10 9 0 13 4 7 2 3 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG5255(Uncharacterized protein conserved in bacteria) 9 14 6 26 0 0 1 0 1 0 0 0 0 0 0 1 0 0 0 1 9 0 6 6 6 0 2 10 0 0 4 8 5 7 25 14 10 15 1 7 2 3 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG18230(Transcriptional regulator protein) 182 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 1 0 0 1 0 1 0 0 0 0 0 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4968(Tfp pilus assembly protein PilE) 106 1 2 2 0 0 0 1 2 1 2 4 2 5 0 5 0 2 2 2 0 3 1 1 0 2 2 0 1 1 1 0 0 0 0 1 17 30 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3481(Predicted HD-superfamily hydrolase) 3 10 35 8 3 1 0 4 3 2 0 2 4 0 2 1 2 1 2 3 2 2 6 0 7 22 0 0 4 1 2 8 4 2 8 7 2 21 2 3 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG4313(Protein involved in meta-pathway of phenol degradation) 190 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12815(Photosystem II oxygen evolving complex protein) 19 5 2 9 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 8 16 9 15 0 2 0 9 16 22 10 2 3 5 0 0 14 15 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG5630(Acetylglutamate synthase) 58 2 0 1 2 0 1 7 8 12 4 9 0 8 17 10 2 2 10 6 3 0 1 0 2 0 2 0 0 0 0 1 1 0 10 2 3 10 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12924(Cytochrome b559 protein) 20 7 5 16 1 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 12 3 19 11 17 3 1 3 8 5 5 9 1 0 5 2 3 18 14 2 0 0 0 0 0 0 2 0 0 0 0 4 0 0 0 0 COG1585(Membrane protein implicated in regulation of membrane protease activity) 8 0 1 1 0 0 0 1 2 0 2 0 0 6 6 5 0 20 5 2 0 1 1 0 0 0 0 0 0 1 0 5 4 0 4 1 0 122 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19480(S-Layer protein) 13 0 1 2 5 1 0 0 0 2 0 0 0 0 0 0 0 0 6 1 6 0 0 5 2 52 4 3 0 3 0 1 0 4 0 0 0 65 15 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 6 NOG22395() 197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08452() 13 4 0 19 1 8 1 0 0 0 0 0 0 0 0 0 0 0 0 7 15 5 13 12 8 0 2 5 5 15 9 13 3 2 1 0 0 12 15 3 0 0 0 0 0 0 0 0 0 1 0 5 0 0 0 1 NOG10819() 11 4 2 14 2 6 1 0 0 0 0 0 0 0 0 0 0 0 1 2 20 3 18 8 12 1 1 2 8 10 14 6 2 2 6 0 0 20 20 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08615() 39 9 14 3 4 5 4 3 0 1 0 0 4 5 4 1 0 1 2 1 6 12 7 2 4 0 7 6 5 2 5 6 6 2 10 7 2 0 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 COG0833(Amino acid transporters) 186 0 1 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3478(Predicted nucleic-acid-binding protein containing a Zn-ribbon domain) 5 4 12 0 0 0 0 1 3 2 0 0 0 2 0 4 0 0 4 5 1 1 5 2 1 0 11 9 6 0 3 14 10 7 15 26 2 0 8 5 4 5 0 0 0 0 0 0 0 0 0 7 0 0 0 13 COG3868(Uncharacterized conserved protein) 172 5 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 7 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09493() 4 7 19 5 1 3 3 10 6 2 1 9 1 10 6 4 1 1 2 5 3 5 2 2 0 1 5 10 2 4 0 3 7 5 10 22 0 0 3 4 6 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG14804(Photosystem I protein) 17 5 0 15 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 11 10 12 6 12 0 3 4 10 12 8 5 1 0 8 1 0 24 13 2 1 4 0 0 0 0 0 0 0 0 0 7 0 1 0 0 NOG08365() 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 42 28 2 0 0 1 2 1 1 77 1 0 1 0 0 3 0 0 0 0 0 32 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG14467() 0 2 2 8 1 0 5 0 4 0 1 3 0 5 8 0 2 8 4 2 2 2 3 7 2 0 5 3 1 1 3 7 10 3 34 18 6 9 8 11 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG25815() 100 3 34 0 0 0 0 2 0 1 2 0 0 0 0 0 0 0 1 4 4 5 4 1 2 0 0 0 11 0 0 0 0 0 2 0 0 0 2 3 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 NOG10596() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 12 12 1 0 0 0 1 1 0 41 2 0 0 0 0 0 0 0 0 0 0 120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG19659() 4 9 4 3 2 3 7 3 3 0 5 1 1 1 0 0 0 0 0 3 4 4 3 2 3 0 3 2 0 0 2 8 3 8 19 8 6 44 2 15 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG14434() 3 3 7 4 5 0 8 3 5 1 2 0 5 5 2 4 1 1 6 1 2 2 13 0 6 4 2 5 1 0 4 10 5 9 23 8 1 10 6 8 1 5 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG09893(Lipopolysaccharide core biosynthesis protein) 1 10 16 8 5 1 2 8 0 0 0 0 3 0 2 4 0 0 0 4 13 3 10 4 7 1 0 6 2 2 4 9 6 1 18 12 10 4 5 7 5 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG07905() 0 1 6 0 9 4 0 3 4 3 0 6 3 4 5 3 0 0 5 4 4 2 8 3 0 1 2 2 0 0 1 8 3 11 20 13 6 12 5 16 4 6 0 0 0 0 0 0 0 0 0 5 0 0 0 3 COG4986(ABC-type anion transport system, duplicated permease component) 144 1 1 3 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 1 0 29 0 2 0 0 0 0 0 0 0 3 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3531(Predicted protein-disulfide isomerase) 62 2 3 4 0 2 0 0 0 0 4 1 0 5 0 3 0 0 1 0 0 0 1 0 2 2 0 0 0 0 0 0 0 0 0 3 10 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5637(Predicted integral membrane protein) 18 5 1 11 1 2 4 0 0 2 0 0 0 1 0 0 0 0 0 1 8 6 15 11 7 0 1 0 7 15 11 8 2 1 13 0 0 21 11 0 3 4 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG10576() 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 7 22 3 1 1 0 0 0 0 57 0 0 0 0 0 0 0 0 0 0 0 102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1637(Predicted nuclease of the RecB family) 0 0 4 0 0 0 0 0 0 0 0 0 0 0 2 0 3 6 3 2 0 1 2 2 2 31 2 1 3 0 1 0 0 0 0 4 5 119 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1798(Diphthamide biosynthesis methyltransferase) 0 5 22 5 0 0 0 0 0 0 0 4 2 3 8 0 0 0 1 5 8 12 8 5 2 8 6 4 9 2 2 9 9 2 0 4 19 2 1 6 7 1 0 0 0 0 0 0 0 0 0 2 0 0 0 12 NOG08898() 155 0 10 0 0 1 0 0 0 0 0 0 1 0 0 0 2 0 0 1 0 0 4 0 1 0 1 2 3 0 0 2 1 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4912(Predicted DNA alkylation repair enzyme) 11 1 5 1 0 0 0 0 0 0 2 0 1 12 2 0 25 14 4 1 1 5 6 1 1 15 5 0 0 2 0 2 0 5 6 24 13 18 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 NOG27478() 5 2 6 4 0 0 2 1 1 0 0 2 2 0 2 2 0 0 1 8 4 6 17 3 6 1 14 8 7 0 4 10 11 3 4 21 0 0 7 1 3 5 0 0 0 0 0 0 0 0 0 4 0 0 0 17 COG4391(Uncharacterized protein conserved in bacteria) 4 3 17 8 3 2 1 3 3 0 1 1 0 23 6 3 7 5 10 4 0 1 5 3 1 4 3 2 1 0 0 6 5 7 6 16 3 14 4 4 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG10756() 16 4 6 4 4 4 4 0 0 0 0 0 0 1 0 0 0 0 0 2 10 5 16 8 16 0 2 5 10 13 12 10 1 4 0 1 0 25 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1285(Uncharacterized membrane protein) 110 0 2 3 0 0 1 0 0 0 0 0 0 3 0 0 5 5 2 1 0 0 1 0 5 4 1 0 1 0 2 0 1 0 4 5 6 31 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG31424() 2 5 11 5 0 1 1 18 1 6 45 1 2 3 4 6 4 4 9 0 0 0 3 0 0 4 12 2 2 6 2 3 5 0 2 4 2 12 0 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11850(Phycoerythrobilin:Ferredoxin oxidoreductase) 10 7 0 17 1 6 5 0 0 0 0 0 0 0 0 0 0 0 0 3 22 7 18 9 7 0 2 4 11 11 10 7 1 4 0 2 0 0 20 4 0 2 0 0 1 0 0 0 0 0 0 3 0 0 0 0 COG1380(Putative effector of murein hydrolase LrgA) 114 1 0 0 0 0 0 1 0 0 0 0 0 3 0 1 4 3 2 0 0 0 0 1 0 2 0 0 0 1 2 2 1 0 0 0 0 55 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 NOG09703() 0 1 5 1 17 2 2 1 2 0 1 2 0 4 2 0 2 5 4 3 0 8 0 2 0 16 3 1 5 3 1 6 2 2 12 9 3 45 3 8 3 6 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG2116(Formate/nitrite family of transporters) 59 5 1 1 1 1 0 2 0 0 0 0 0 1 0 0 0 0 2 1 3 1 1 2 2 0 3 0 3 4 1 8 0 2 0 3 4 56 22 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1401(GTPase subunit of restriction endonuclease) 6 9 8 4 2 1 1 4 2 3 5 0 0 6 0 3 4 4 2 2 6 6 5 4 5 14 6 3 3 0 2 8 1 0 4 7 3 44 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14802(Protein involved in cell organization and biogenesis) 11 6 2 5 4 4 1 0 0 1 0 0 0 0 0 0 0 0 3 1 8 11 20 13 12 2 1 4 10 5 12 9 2 0 2 0 0 19 16 2 1 0 0 0 0 0 0 0 0 0 0 2 0 1 2 1 COG3664(Beta-xylosidase) 6 4 0 0 1 3 0 5 1 0 2 0 0 2 0 0 2 0 1 1 0 0 1 0 0 0 2 0 1 3 0 1 6 0 7 3 4 132 0 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10816() 14 8 0 11 1 5 1 0 0 0 0 0 0 0 0 0 0 0 1 0 19 4 12 12 10 0 2 1 5 15 8 7 0 1 6 1 0 31 16 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG12858() 20 6 1 11 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 10 27 14 10 0 2 2 11 14 5 9 0 4 0 0 0 24 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12953() 3 8 11 19 0 2 5 2 0 0 0 3 0 0 2 3 0 0 0 0 8 4 7 8 0 4 5 5 7 0 3 6 6 8 16 13 7 9 6 5 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG34949() 9 6 0 13 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 16 4 17 15 19 0 0 9 7 14 11 4 2 1 6 0 0 19 14 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG21509() 1 4 16 9 0 1 5 3 0 1 2 5 0 10 4 1 5 2 3 4 2 0 2 3 0 6 10 3 3 0 2 5 6 6 14 13 2 19 3 5 3 2 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG20087() 3 6 18 8 1 4 0 2 2 0 3 0 1 3 4 1 0 0 0 4 0 9 14 3 4 0 0 5 1 0 5 5 10 7 25 16 3 0 7 10 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG11849(15,16-Dihydrobiliverdin:Ferredoxin protein) 12 8 3 11 2 4 5 2 0 0 0 0 0 0 0 0 0 0 0 0 19 6 15 7 4 0 3 11 11 12 10 8 0 4 9 0 0 2 20 0 0 1 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG07989(Secreted protein) 1 11 8 7 0 1 0 2 0 1 10 5 2 17 1 4 5 1 3 3 2 1 6 5 2 2 5 4 2 3 4 3 3 2 4 1 11 37 1 7 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG27356() 5 2 10 1 1 0 5 2 4 5 9 0 2 3 0 0 0 2 0 5 7 6 6 3 0 4 3 4 2 4 2 7 6 2 27 16 1 3 2 13 2 4 0 0 0 0 0 0 0 0 0 6 0 0 0 6 NOG10845() 30 1 0 4 4 1 3 0 0 0 0 0 2 0 0 0 0 0 0 4 9 1 2 5 6 0 6 4 0 10 0 9 4 6 0 0 0 34 40 1 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG2048(Heterodisulfide reductase, subunit B) 0 8 30 6 0 0 0 0 0 0 0 0 2 4 1 0 0 0 0 7 10 13 20 7 1 2 2 8 7 1 1 11 14 2 0 7 3 1 6 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 NOG26097() 3 3 4 3 6 1 0 6 6 2 1 5 4 2 2 0 0 0 7 2 5 1 5 0 6 5 1 9 1 1 0 10 6 5 20 18 0 7 4 14 5 8 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG07992() 12 1 4 9 4 1 2 3 5 0 1 6 0 5 0 0 3 2 8 2 6 4 9 10 8 1 5 4 4 0 5 13 6 8 14 6 3 3 4 2 3 2 0 0 0 0 0 0 0 0 0 1 0 0 1 2 COG1939(Uncharacterized protein conserved in bacteria) 19 3 5 15 4 1 2 0 0 1 0 0 0 0 0 0 0 0 0 0 8 5 16 9 14 0 3 7 6 6 9 13 2 0 3 4 0 17 18 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG38505(Ribosomal protein) 1 5 2 2 2 1 7 4 9 0 2 3 4 8 0 1 0 2 4 7 3 6 8 1 0 1 5 5 2 1 2 9 6 7 21 17 3 1 1 14 5 6 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG4804(Uncharacterized conserved protein) 122 5 2 1 2 3 0 0 0 0 0 0 0 0 0 3 2 8 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 2 0 23 7 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09617() 161 1 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 1 2 0 0 0 0 0 0 0 2 1 2 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17457() 1 3 5 5 2 0 3 3 2 4 5 5 0 10 1 1 0 3 2 5 3 6 5 5 6 7 1 6 2 0 1 4 7 5 29 19 2 3 0 9 3 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG2060(K+-transporting ATPase, A chain) 182 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10800() 14 2 2 7 1 0 4 0 0 2 0 0 0 0 0 0 0 0 0 1 18 2 18 14 15 0 0 2 11 8 14 5 5 1 9 1 0 15 8 3 0 0 0 0 0 0 0 0 0 0 0 5 1 0 1 2 NOG16002(Atp/Gtp-Binding protein) 0 0 1 0 0 0 0 0 0 0 3 0 0 0 0 0 23 21 3 0 4 2 0 0 0 43 1 0 1 0 0 0 0 0 0 7 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22661(C4-Dicarboxylate transporter protein) 3 5 6 5 0 1 0 0 3 2 2 1 1 7 3 0 0 3 5 3 2 6 6 3 2 0 1 2 4 0 5 5 5 7 9 5 12 40 8 7 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 8 NOG12965() 19 4 0 9 3 5 2 0 0 0 0 0 0 0 0 0 0 0 1 0 6 7 13 7 20 0 4 9 6 15 3 5 5 0 0 2 0 26 14 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG1229(Formylmethanofuran dehydrogenase subunit A) 9 12 10 11 0 0 1 4 2 4 2 2 1 0 2 3 1 4 0 0 3 8 4 7 3 5 3 4 3 1 3 6 1 2 6 16 2 34 3 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG2808(Transcriptional regulator) 80 4 2 3 1 0 1 2 0 0 3 0 0 9 0 1 6 3 6 0 3 1 2 1 0 14 3 1 1 1 0 0 3 3 6 1 8 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10732(Photosystem I protein) 15 5 3 9 0 3 3 2 0 2 0 0 0 0 0 0 0 0 1 2 19 4 10 10 14 0 0 10 5 11 8 8 1 0 4 1 0 11 10 2 1 4 0 0 0 0 0 0 0 2 0 10 0 0 0 0 NOG19743() 4 5 6 11 0 2 2 3 0 2 0 2 4 8 6 7 11 2 9 5 1 2 5 0 2 8 5 0 1 0 0 4 0 4 2 3 8 38 2 4 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 6 COG3977(Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase) 131 3 2 1 4 3 0 6 1 0 2 0 0 4 2 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 5 0 2 0 2 1 11 4 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG17207() 4 9 17 13 0 1 3 0 3 2 0 7 0 1 3 5 2 1 1 1 4 0 1 3 1 0 0 7 4 0 1 13 10 9 18 17 2 2 5 8 4 4 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG22484(Protein involved in cell organization and biogenesis) 170 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 6 4 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08034() 1 2 1 3 0 4 3 4 1 1 4 2 2 10 2 4 0 0 2 4 0 2 4 0 0 0 4 2 1 2 0 6 10 9 24 23 8 13 6 13 3 3 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG12929() 0 1 2 0 0 0 0 0 0 0 1 1 0 5 0 0 15 37 1 0 1 0 0 0 0 52 0 0 0 0 0 0 0 0 0 2 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3433(Aryl carrier domain) 173 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35230(Sprt homologues) 3 5 1 4 1 10 0 2 2 2 1 0 0 2 2 2 3 5 7 1 3 2 3 3 4 7 5 3 2 0 2 10 7 0 9 9 0 56 3 2 3 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3770(Murein endopeptidase) 17 2 3 5 1 0 3 0 3 3 1 1 1 8 2 3 0 0 3 2 3 1 2 5 4 0 3 1 3 0 4 4 5 9 6 9 0 56 4 0 1 6 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG2102(Predicted ATPases of PP-loop superfamily) 11 7 22 6 0 2 0 0 2 0 1 2 3 4 4 0 0 0 2 4 3 5 10 5 0 9 5 1 3 7 1 3 6 6 1 7 20 7 1 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 COG1095(DNA-directed RNA polymerase, subunit E) 22 3 12 3 0 0 0 1 0 3 0 1 0 2 5 1 3 2 1 5 5 14 3 2 2 6 2 3 4 5 5 5 4 5 0 7 18 0 11 9 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG2237(Predicted membrane protein) 2 9 12 4 0 0 0 0 0 0 0 1 3 2 4 1 0 0 0 7 3 8 13 8 9 17 1 0 5 4 2 6 12 0 0 20 4 0 2 4 7 3 0 0 0 0 0 0 0 0 0 2 0 0 0 14 NOG06256() 12 8 13 9 0 1 2 2 1 2 0 0 0 0 0 1 3 6 1 3 5 6 6 8 2 1 0 1 1 0 1 8 2 12 19 22 0 8 12 2 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1669(Predicted nucleotidyltransferases) 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 3 1 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 11 161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3659(Carbohydrate-selective porin) 120 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 5 4 0 0 0 1 4 0 0 1 1 1 3 0 0 1 2 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3010(Putative N-acetylmannosamine-6-phosphate epimerase) 7 3 1 5 3 0 3 0 0 4 0 0 0 0 2 0 6 14 4 3 2 0 4 2 4 11 1 0 0 4 0 9 8 0 4 12 3 51 13 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG19569() 3 22 29 12 0 2 2 0 0 0 0 0 0 0 0 1 0 3 0 3 5 8 12 4 3 1 1 3 3 3 1 6 2 5 9 36 0 0 3 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG16599() 10 3 0 0 2 1 1 0 2 0 3 0 0 13 4 0 8 6 6 3 2 0 3 2 2 7 0 3 0 0 2 2 1 0 7 1 12 79 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3947(Response regulator containing CheY-like receiver and SARP domains) 15 4 3 2 0 0 0 2 2 1 3 3 3 11 0 0 5 5 3 1 6 0 3 3 7 12 2 2 6 1 0 4 2 2 9 3 8 39 3 0 2 5 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG19756() 3 8 4 2 0 1 7 1 5 0 0 3 2 1 2 2 2 8 3 6 10 7 7 5 2 17 1 1 5 0 8 5 4 2 3 27 0 1 5 1 3 6 0 0 0 0 0 0 0 0 0 3 0 0 0 5 NOG25041() 2 4 8 6 2 1 9 10 10 0 2 9 7 2 2 0 2 2 1 2 0 2 5 2 7 1 5 12 4 2 2 11 6 0 22 7 0 0 3 10 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG04010() 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 4 3 13 2 0 0 6 0 1 0 52 1 0 1 0 2 0 2 0 0 23 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29342() 185 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12661() 3 2 4 3 0 0 0 0 0 0 0 0 0 5 2 1 0 1 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 1 2 3 0 154 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21416() 162 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15928(UPF0233 membrane protein) 0 0 0 0 0 0 0 0 0 2 2 0 0 3 0 0 18 30 2 0 0 0 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06428() 0 6 17 11 1 0 0 4 0 0 2 0 0 5 4 0 20 14 4 0 0 1 1 6 1 61 1 0 3 1 1 0 0 0 0 5 6 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12645() 0 0 0 0 0 0 0 2 0 0 2 0 0 2 2 0 19 14 4 0 3 0 0 0 0 45 0 0 0 0 0 2 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06089() 144 4 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 1 0 1 0 0 0 0 4 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08648(Type II restriction protein) 3 8 5 6 0 3 0 0 0 0 2 0 1 3 4 0 5 2 3 2 0 3 9 4 2 16 1 2 2 0 3 7 5 0 8 10 6 44 1 2 1 4 0 0 0 0 0 0 0 0 0 4 0 0 0 5 NOG14508() 0 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 29 19 1 3 3 5 3 2 2 79 1 0 1 1 0 5 5 0 0 4 0 3 0 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 NOG27508() 0 0 7 1 0 0 3 3 3 0 5 7 2 2 2 9 0 4 3 4 3 3 10 5 1 4 3 3 3 0 0 11 11 3 21 26 2 3 8 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG13042() 3 4 5 4 0 0 0 1 3 4 3 2 1 8 6 0 5 6 6 6 0 1 5 0 0 17 5 6 2 3 1 7 1 1 8 12 2 36 2 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG22262() 8 13 3 10 0 0 8 4 0 5 0 4 1 0 2 2 1 7 2 6 9 4 11 8 7 0 1 7 7 0 4 6 9 7 9 4 0 0 3 1 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 7 COG4573(Predicted tagatose 6-phosphate kinase) 89 1 2 1 0 0 0 2 0 0 0 0 5 0 3 3 0 0 1 0 0 3 0 1 0 0 0 3 0 0 0 6 4 2 4 10 2 39 0 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG37696() 10 2 1 12 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 20 6 20 12 19 1 3 1 6 9 7 12 3 0 5 2 0 27 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14807() 67 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 2 109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16209() 15 5 1 10 2 4 0 0 0 2 0 0 0 0 0 0 0 0 0 0 10 2 26 9 16 0 0 2 15 9 8 3 2 0 4 1 0 25 7 0 0 3 0 0 0 0 0 0 1 0 0 2 0 0 0 1 NOG12999() 2 0 1 0 0 0 0 0 0 0 0 0 0 0 2 1 2 2 7 0 0 1 3 0 0 19 0 0 0 1 2 0 1 0 2 0 0 137 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1990(Uncharacterized conserved protein) 1 4 9 8 0 2 0 0 0 0 3 2 0 1 6 3 0 2 1 4 7 8 11 4 5 12 2 4 4 4 0 13 5 7 0 11 9 6 7 5 4 3 0 0 0 0 0 0 0 0 0 2 0 0 0 5 COG1097(RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)) 1 4 22 7 0 1 0 2 1 0 0 4 0 0 11 2 1 2 0 0 4 5 7 4 3 9 2 4 1 4 0 4 7 6 1 8 32 4 0 5 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 11 NOG16668() 4 0 0 0 0 1 0 26 18 1 3 9 27 5 2 3 1 5 4 22 0 0 0 0 0 6 0 0 0 0 0 0 0 2 0 0 13 23 0 4 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12798(Protein involved in oxidative phosphorylation) 14 4 0 13 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 9 2 20 5 12 0 1 4 19 8 12 10 1 0 4 0 0 22 18 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 NOG11646() 3 2 8 2 3 0 8 0 1 0 0 3 0 8 0 2 4 3 3 0 0 7 7 1 4 1 2 1 4 2 2 6 3 8 18 12 4 17 7 12 6 3 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG12872() 15 3 3 12 1 4 1 0 0 0 0 0 1 0 0 0 0 0 0 0 15 3 23 13 5 3 0 9 5 9 8 6 0 0 4 0 0 21 16 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3745(Flp pilus assembly protein CpaB) 126 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 4 0 0 1 2 0 0 0 0 0 0 9 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4257(Streptogramin lyase) 3 11 18 11 2 0 0 2 0 4 0 0 0 7 2 2 0 2 1 2 4 2 3 0 1 20 2 0 0 3 0 2 0 0 2 7 2 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09653() 0 1 5 2 1 3 1 8 0 3 6 0 2 9 0 1 2 2 5 1 0 0 0 1 2 0 7 6 3 0 0 3 5 6 26 12 2 12 10 14 4 2 0 0 0 0 0 0 0 0 0 12 0 0 0 5 NOG31573() 2 2 2 1 9 0 12 5 6 0 0 2 2 2 0 3 2 0 1 2 3 6 4 2 2 3 2 4 3 2 3 10 6 8 20 10 2 0 4 24 3 1 0 0 0 0 0 0 0 0 0 5 0 0 0 4 COG4678(Muramidase (phage lambda lysozyme)) 16 0 1 1 1 3 3 10 3 0 0 0 1 0 2 0 0 2 2 2 1 0 1 2 0 2 1 0 0 3 0 7 2 0 4 0 0 71 38 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 NOG28562() 13 2 2 14 3 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 8 7 24 6 10 0 5 5 8 14 21 7 1 0 2 0 0 12 11 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG16448(Photosystem I reaction center subunit IV) 11 5 4 14 6 4 2 0 0 1 0 0 0 0 0 0 0 0 1 0 7 3 18 14 6 2 0 2 7 9 8 10 1 0 3 0 0 21 16 0 0 2 0 0 0 0 0 0 0 1 0 5 0 0 0 0 COG5031(Uncharacterized protein involved in ubiquinone biosynthesis) 8 6 12 14 3 2 1 6 1 0 4 0 3 5 0 0 2 0 0 2 4 1 3 5 2 1 2 0 3 1 0 17 2 8 0 13 2 41 2 1 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG16564() 14 6 3 9 4 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 15 5 13 9 11 0 2 6 6 14 9 10 2 0 2 0 0 0 32 2 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG16493() 8 10 11 17 1 1 0 5 0 0 0 1 2 4 0 3 0 2 6 5 7 8 7 7 4 29 0 1 2 1 7 3 5 0 0 11 2 1 5 1 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 3 NOG14438() 1 1 5 3 8 0 5 7 5 1 1 0 2 0 0 3 4 3 3 0 0 7 7 2 1 1 2 2 0 0 3 9 10 8 26 12 2 7 7 11 5 4 0 0 0 1 0 0 0 0 0 2 0 0 0 2 COG3865(Uncharacterized protein conserved in bacteria) 85 0 1 0 0 0 0 0 0 0 0 2 0 1 0 0 13 10 0 0 2 2 0 0 0 57 0 0 0 1 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG14745() 5 1 1 0 0 1 0 3 0 2 5 0 2 11 0 1 11 0 4 0 0 1 0 1 0 17 0 0 0 0 5 5 2 0 0 4 8 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28220(Sprt homologues) 18 3 0 18 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5 6 8 7 15 0 1 4 15 19 8 5 5 0 2 0 0 21 14 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4529(Uncharacterized protein conserved in bacteria) 11 4 4 3 0 0 2 2 0 0 0 0 0 8 2 2 2 0 3 3 0 9 2 3 0 34 11 0 7 2 0 11 2 7 12 1 3 10 16 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13497() 9 5 19 5 0 2 0 1 2 5 0 0 3 4 0 3 0 0 1 0 0 4 1 0 0 1 1 4 2 0 0 18 7 9 22 17 3 6 10 10 1 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4354(Predicted bile acid beta-glucosidase) 19 2 3 0 7 1 0 2 0 2 0 0 0 0 0 0 0 6 0 1 7 0 1 0 0 1 3 10 0 13 0 9 3 3 10 0 2 50 19 5 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG34860() 0 0 0 2 0 0 0 19 2 0 0 2 11 2 0 0 1 0 4 0 0 1 1 0 0 0 0 0 0 0 0 0 0 4 0 2 0 130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG11671(Mercuric transport protein) 160 9 0 0 1 0 0 0 0 0 4 0 0 0 0 1 0 0 4 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2123(RNase PH-related exoribonuclease) 2 5 19 3 1 1 0 0 0 0 0 0 0 3 11 0 1 0 0 3 7 6 6 4 2 11 1 6 5 9 2 9 5 2 2 12 19 1 3 0 4 3 2 0 0 0 0 0 0 0 0 0 0 0 0 12 COG1512(Beta-propeller domains of methanol dehydrogenase type) 15 0 0 2 4 3 2 0 1 0 3 1 0 9 1 2 3 10 7 1 0 1 2 1 0 20 3 1 1 1 2 7 1 1 0 1 13 47 10 1 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG20554(Cytochrome c protein) 86 1 3 0 0 0 0 0 0 0 0 0 0 4 4 0 0 2 0 0 0 0 0 0 1 3 1 0 0 1 0 0 0 0 0 1 8 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5495(Uncharacterized conserved protein) 47 0 4 0 1 0 0 0 0 0 3 0 0 12 0 1 4 4 1 3 2 1 2 1 0 1 0 0 1 1 0 0 0 0 4 6 3 75 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG32176() 14 8 0 15 1 2 0 0 0 3 0 0 0 0 0 0 0 0 0 2 17 5 20 8 12 0 2 3 8 5 8 9 0 3 0 0 0 16 16 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG1926(Predicted phosphoribosyltransferases) 53 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 7 2 0 0 0 0 0 0 0 22 2 0 0 2 0 0 0 0 0 0 2 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2357(Uncharacterized protein conserved in bacteria) 9 2 12 2 0 0 0 3 1 1 3 4 0 10 8 3 2 2 0 0 4 2 0 3 1 0 3 7 1 0 2 3 3 9 4 7 10 56 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1094(Predicted RNA-binding protein (contains KH domains)) 1 3 15 6 3 5 0 0 0 2 0 0 0 3 11 3 1 0 0 4 5 6 7 3 1 5 2 2 2 6 1 5 13 2 0 8 14 1 0 10 7 10 0 0 0 0 0 0 0 0 0 3 0 0 0 12 NOG08826(EC 2.7.-.- Stealth protein) 4 5 3 3 3 0 4 1 4 3 3 7 1 8 4 2 0 4 3 0 4 1 4 3 5 0 1 5 1 3 0 9 9 8 23 19 0 2 0 13 3 1 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG10563() 0 0 0 1 0 0 0 0 2 0 0 0 0 0 0 0 26 28 2 1 2 1 1 0 0 77 0 0 0 0 0 0 0 0 0 4 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25439() 2 0 8 1 3 0 4 6 4 2 2 3 0 0 1 2 0 4 3 0 1 2 4 0 1 0 5 2 3 0 2 18 2 4 30 18 6 19 3 14 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19136() 1 3 6 2 5 1 4 2 3 2 3 1 0 3 4 2 3 0 1 5 3 1 1 3 0 1 1 2 5 0 0 8 7 8 31 30 0 6 4 13 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG31462() 18 3 1 12 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 4 14 15 11 0 1 3 6 6 16 8 0 3 2 2 0 22 15 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26015() 179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4649(Uncharacterized protein conserved in bacteria) 9 8 11 8 0 4 1 0 0 2 2 1 0 6 2 0 0 0 2 6 1 3 6 3 4 0 2 5 1 1 6 8 4 6 20 15 3 8 8 5 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG5377(Phage-related protein, predicted endonuclease) 70 1 0 0 0 0 0 9 5 4 2 0 5 3 4 1 4 4 4 0 5 1 0 0 2 9 4 0 2 1 3 2 4 0 0 0 2 28 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17094(Lipoprotein) 25 5 4 1 6 0 2 5 2 3 3 5 4 6 0 4 4 4 2 5 0 1 4 0 3 5 6 7 3 1 1 8 5 1 12 10 2 13 0 2 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08828() 0 0 4 0 0 0 0 0 0 0 0 0 1 5 0 2 4 22 4 0 1 3 4 1 0 69 2 1 2 0 0 0 0 0 0 12 0 40 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG18143() 30 0 3 3 0 2 1 3 1 0 0 0 0 3 6 2 2 0 0 1 2 3 5 2 4 35 2 4 12 13 11 2 2 2 2 3 0 13 1 0 2 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG5323(Uncharacterized conserved protein) 0 0 0 1 0 2 0 13 0 1 6 3 0 6 0 3 2 1 10 0 2 2 1 0 1 10 2 2 1 4 1 5 5 6 2 2 2 75 0 3 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG12250(Recombination protein) 0 0 2 1 0 0 0 9 1 2 18 1 4 0 1 0 1 2 11 0 0 0 2 1 0 0 2 1 0 1 2 2 1 2 0 2 2 103 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2007(Ribosomal protein S8E) 0 6 15 8 2 3 0 0 0 0 0 5 1 9 0 0 0 0 1 8 3 9 3 5 3 15 1 4 2 2 0 7 6 0 2 14 22 4 0 6 1 1 0 0 0 0 0 0 0 0 0 4 1 0 0 6 COG1471(Ribosomal protein S4E) 0 5 11 6 0 2 0 0 0 0 0 0 0 6 4 0 2 1 2 3 12 4 8 2 0 9 7 1 5 5 5 7 4 0 0 14 23 0 5 4 8 7 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG08488() 11 5 0 7 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 20 9 17 16 9 0 0 3 11 8 12 17 3 0 3 0 0 21 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG23635() 10 3 0 11 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 17 9 17 12 10 2 4 4 7 13 12 3 0 0 0 0 0 22 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10795() 15 4 1 12 1 5 0 0 0 0 0 0 0 0 0 0 0 0 1 0 6 5 9 9 13 0 1 4 3 9 7 7 3 2 11 4 0 38 5 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG1244(Predicted Fe-S oxidoreductase) 0 2 11 3 0 0 0 3 1 0 0 0 4 7 0 1 0 0 1 6 5 6 17 6 4 0 1 4 5 3 0 15 15 1 0 7 2 11 4 5 10 2 2 0 0 0 2 0 0 0 0 4 0 0 0 9 COG3301(Formate-dependent nitrite reductase, membrane component) 166 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08607() 53 2 4 1 0 0 2 7 4 2 3 0 0 8 2 4 2 1 2 0 0 2 7 0 7 1 5 0 1 0 0 2 7 2 8 9 0 24 0 2 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG1580(Flagellar basal body-associated protein) 111 10 2 2 0 0 0 0 1 1 2 0 0 2 4 0 1 0 7 0 0 0 5 2 1 5 3 3 0 0 0 3 1 0 2 0 1 8 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08088() 9 4 20 6 1 0 0 6 0 0 0 0 1 2 4 1 0 2 6 10 7 9 13 4 7 0 2 2 4 5 2 6 0 0 0 11 0 14 8 4 1 3 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG0409(Hydrogenase maturation factor) 43 1 1 0 0 0 0 0 0 0 0 0 0 3 2 2 0 3 1 0 0 2 0 1 0 2 0 0 0 0 0 0 0 0 0 2 6 109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11790(Nudix family protein) 12 6 0 2 0 2 2 2 0 6 2 0 0 9 1 1 0 0 1 3 5 1 4 3 1 0 5 0 3 4 1 5 8 5 17 15 0 18 3 12 4 6 0 0 0 0 0 0 0 0 0 5 0 0 0 4 COG3002(Uncharacterized protein conserved in bacteria) 0 0 5 5 0 0 0 0 0 0 0 0 3 0 8 0 4 0 0 0 0 0 2 4 0 8 1 0 0 0 0 1 0 0 0 0 5 132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13923() 177 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10092() 5 6 9 11 0 1 6 2 0 0 0 0 0 0 4 0 0 0 1 0 1 2 5 4 1 0 2 5 4 0 0 10 5 10 10 6 0 53 0 6 1 6 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13655() 1 6 4 4 0 0 1 0 6 1 2 0 2 0 2 0 9 7 1 2 1 0 7 2 1 17 5 4 0 5 0 1 6 0 6 10 0 41 3 2 4 4 0 0 0 0 0 0 0 0 0 1 0 0 0 10 COG3235(Predicted membrane protein) 75 5 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 1 0 0 0 0 1 0 0 0 0 2 0 0 7 81 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21432() 10 4 0 8 1 1 3 0 0 0 0 0 0 0 0 0 0 1 1 3 18 8 9 6 7 7 0 4 8 9 16 11 2 2 5 1 0 14 11 4 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG12963() 12 7 3 13 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 20 9 16 0 1 3 11 10 10 5 0 0 4 0 0 19 12 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 COG3131(Periplasmic glucans biosynthesis protein) 146 6 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 1 0 0 2 0 0 1 0 1 0 0 0 0 0 2 10 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04402(Single-Strand selective monofunctional uracil DNA glycosylase) 1 2 8 1 3 4 0 0 0 0 0 0 0 6 4 1 0 0 2 9 3 14 7 1 3 2 9 7 3 1 2 20 11 0 2 7 2 20 1 3 6 7 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG06276() 130 9 3 3 2 0 0 0 0 0 0 2 2 0 0 0 2 0 0 0 7 0 1 2 2 4 0 0 0 1 2 1 1 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1900(Uncharacterized conserved protein) 8 8 1 9 4 0 6 2 0 0 0 0 0 0 0 0 0 2 0 1 15 10 19 3 14 1 1 4 7 7 10 2 1 2 9 9 0 13 5 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38393() 7 6 0 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 19 9 15 7 17 0 3 4 3 7 14 8 2 2 2 0 0 22 13 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 COG1650(Uncharacterized protein conserved in archaea) 1 6 25 10 0 0 0 0 0 0 0 2 0 5 6 2 1 0 5 3 2 3 4 2 1 13 1 4 4 3 4 7 8 0 2 5 8 0 6 6 7 9 0 1 0 0 0 0 0 0 0 6 0 0 0 5 COG1500(Predicted exosome subunit) 2 5 14 5 0 1 0 1 2 0 0 6 0 0 10 1 3 0 0 0 5 7 12 6 4 7 2 0 1 5 1 3 7 1 2 7 22 6 1 7 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 14 COG5273(Uncharacterized protein containing DHHC-type Zn finger) 0 7 7 15 14 18 0 1 1 2 0 0 0 8 0 0 6 0 0 5 2 7 5 1 22 0 0 3 1 31 0 9 0 0 0 7 1 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12509() 2 25 66 17 0 0 1 0 0 0 0 0 0 6 0 0 2 0 1 7 2 1 3 2 0 20 4 2 0 0 2 1 0 0 0 3 0 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG5351(Uncharacterized protein conserved in bacteria) 124 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13328() 26 2 5 11 0 0 2 0 0 0 0 3 1 0 3 0 2 0 0 2 10 7 15 11 14 0 2 0 8 6 2 11 0 1 3 4 0 13 10 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2899(Uncharacterized protein conserved in bacteria) 59 2 5 1 0 1 0 2 2 2 2 0 0 4 1 1 0 2 0 1 3 2 1 2 0 2 3 1 4 0 2 2 8 0 16 12 3 0 5 14 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG23548() 1 1 2 2 2 4 1 8 1 0 0 0 0 6 6 2 2 5 7 3 0 4 0 0 2 13 10 1 2 2 4 5 4 5 17 4 5 33 4 3 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5238(Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport) 0 9 21 8 25 40 0 3 0 2 0 0 0 2 0 1 0 0 1 1 3 1 1 0 5 0 0 2 1 29 0 2 0 2 0 1 2 10 1 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG19690() 5 1 1 2 1 4 0 0 1 0 1 0 2 4 2 1 2 2 3 0 2 5 3 5 3 0 5 4 3 0 0 0 1 2 3 6 2 94 0 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2715(Uncharacterized membrane protein, required for spore maturation in B.subtilis.) 58 3 22 4 0 3 0 0 1 1 0 1 0 2 2 1 4 3 2 1 5 1 5 2 9 11 3 3 2 0 3 6 5 0 2 1 4 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG25976() 14 12 2 9 4 14 10 0 0 0 1 0 0 2 0 0 0 0 1 0 6 3 11 8 5 0 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04009() 0 0 2 2 0 0 0 0 0 0 0 0 0 4 2 0 1 20 0 1 2 0 1 0 0 51 4 1 0 0 0 0 1 0 0 22 5 55 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG14801(Protein involved in photosynthesis) 13 2 1 9 3 2 0 2 0 2 0 0 0 0 0 0 0 0 0 3 10 6 10 10 17 0 0 7 12 10 10 10 2 2 10 0 0 0 19 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 NOG38769() 0 0 1 3 2 0 0 6 5 1 1 5 8 2 0 6 8 8 2 5 0 0 3 0 0 37 7 2 1 1 0 7 7 2 0 15 0 13 8 2 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG4303(Ethanolamine ammonia-lyase, large subunit) 139 1 2 2 1 0 0 3 1 0 0 0 0 2 0 3 0 2 0 0 0 0 0 0 0 2 2 0 0 0 0 0 1 0 4 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22624() 0 0 0 0 0 0 1 0 0 0 0 0 0 2 0 2 28 30 1 0 0 0 0 0 1 68 0 2 0 0 0 1 0 0 0 2 1 33 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG12893() 9 6 0 8 1 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 23 3 14 12 16 0 0 5 12 16 15 3 0 1 9 0 0 0 13 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4637(Predicted ATPase) 128 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 1 0 6 0 0 0 0 0 4 0 0 0 0 0 0 2 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12610(UPF0336 protein) 1 1 5 2 0 0 0 0 1 0 0 1 0 2 0 0 15 16 2 0 0 1 0 1 0 11 0 0 0 0 0 2 0 0 0 1 0 113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14774() 5 5 6 2 0 1 2 1 2 2 0 0 1 7 0 4 0 0 4 3 4 2 5 5 2 0 5 3 3 0 2 8 8 3 24 13 0 18 8 3 3 6 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG10811() 11 7 1 8 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 11 7 8 9 18 2 1 2 7 11 5 10 3 2 2 0 0 31 6 1 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 1 NOG07919(Type IV prepilin protein) 150 0 3 0 0 0 0 0 3 0 1 0 0 1 0 0 0 0 1 0 0 0 0 0 0 10 0 0 0 2 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32461() 17 1 0 11 2 7 3 0 0 0 0 0 0 0 0 0 0 0 0 5 15 1 16 5 12 0 1 5 7 6 7 10 4 0 4 0 0 23 7 4 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG10059() 4 2 1 4 0 5 0 0 0 0 0 0 0 5 2 1 9 5 3 1 4 8 6 3 5 2 4 0 4 0 0 3 2 2 2 5 0 77 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16891() 4 2 2 2 0 1 0 4 0 0 0 0 5 6 2 0 0 0 3 1 3 2 8 4 4 0 8 3 1 0 0 4 4 2 14 3 2 51 9 12 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG10603() 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 24 25 1 1 2 0 0 0 0 73 1 0 0 0 0 1 0 2 0 4 0 37 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05998() 76 3 1 0 2 0 0 0 2 0 2 1 0 0 0 0 0 1 8 0 4 0 1 2 4 0 3 0 0 0 0 0 2 1 4 0 23 32 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04153() 0 0 22 0 0 0 0 4 0 2 0 0 0 7 2 6 8 10 8 3 7 21 11 2 2 3 2 0 8 4 4 9 0 0 4 13 0 2 0 2 1 2 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG4966(Tfp pilus assembly protein PilW) 136 0 1 1 0 0 0 0 0 0 2 0 0 1 0 2 2 1 1 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 16 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09725() 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 25 25 4 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09459() 20 1 0 3 1 3 3 0 0 0 0 0 0 0 0 0 0 1 1 0 10 0 5 0 8 3 1 0 3 4 0 7 3 2 0 0 0 74 14 1 0 0 0 0 2 0 0 0 0 0 0 3 0 0 1 0 NOG18219() 1 7 9 5 1 0 1 1 2 1 5 6 0 3 4 1 4 1 1 5 0 9 10 1 4 8 4 5 2 2 2 13 8 0 10 11 3 0 1 14 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG1626(Neutral trehalase) 95 10 12 5 1 4 0 0 0 0 0 0 0 0 2 0 0 3 0 1 0 2 1 1 0 0 0 0 0 1 0 2 1 0 2 6 12 12 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26575() 1 13 24 4 3 1 2 2 4 1 0 2 1 5 6 3 0 0 3 0 2 4 10 0 0 5 2 0 4 2 0 5 5 9 10 14 3 5 5 6 0 2 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG11851() 54 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 1 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5469(Predicted metal-binding protein) 9 5 5 9 2 3 3 1 0 0 1 0 2 6 2 0 2 0 3 3 4 3 9 5 4 1 1 1 2 1 1 7 1 4 22 1 0 19 11 10 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG22619() 0 1 4 1 0 0 0 0 0 0 0 0 0 2 0 0 6 13 4 0 2 5 1 1 6 14 2 0 2 0 0 6 4 1 2 16 0 72 0 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG32101() 5 6 5 7 1 1 10 10 3 2 8 3 6 20 4 2 6 0 5 2 4 0 5 10 5 0 2 2 2 0 3 3 2 0 8 4 2 2 2 2 1 2 0 0 0 0 0 0 0 1 0 2 0 0 0 3 NOG14797() 19 3 0 9 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 15 4 15 11 13 0 1 3 6 14 10 1 0 0 0 0 0 28 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11421() 57 0 0 0 0 0 0 0 2 0 0 2 0 1 2 1 13 5 4 1 0 0 3 0 0 48 1 0 1 0 0 1 0 2 2 1 1 20 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG33339() 173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08703() 8 5 5 10 0 1 2 2 0 0 1 2 1 3 0 2 5 4 4 0 4 0 9 1 4 11 4 4 9 2 3 5 1 4 4 9 2 29 2 6 2 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG16574() 10 8 1 11 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 3 15 1 15 10 10 0 0 5 2 10 13 7 2 1 3 0 0 27 8 2 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 COG4766(Ethanolamine utilization protein) 12 12 9 6 0 0 2 7 3 0 0 2 0 5 0 1 2 0 2 1 0 0 0 0 1 0 0 0 0 0 0 1 3 1 12 87 0 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5512(Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives) 0 0 2 0 0 0 0 0 1 0 1 0 0 3 0 1 16 26 5 0 0 0 0 0 0 48 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36064(Protein SSO1033) 2 2 0 0 0 0 0 0 0 0 0 0 0 4 0 3 17 7 0 0 2 2 0 0 0 48 2 0 0 0 0 0 3 0 0 0 5 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4101(Predicted mannose-6-phosphate isomerase) 7 3 14 8 2 8 1 6 1 4 3 0 0 5 4 0 1 0 4 7 2 5 7 5 4 0 4 4 4 0 3 4 2 4 16 5 2 6 0 7 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG3736(Type IV secretory pathway, component VirB8) 160 2 1 1 1 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3124(Uncharacterized protein conserved in bacteria) 40 7 0 3 8 0 1 0 3 2 2 1 0 7 11 1 7 4 2 5 0 0 0 2 0 1 3 6 3 0 3 3 5 2 10 3 0 9 4 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3832(Uncharacterized conserved protein) 103 2 0 0 0 0 1 0 0 0 0 2 0 0 0 0 6 0 0 0 2 0 0 1 0 18 0 0 0 0 0 2 0 0 4 0 11 18 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3657(Uncharacterized protein conserved in bacteria) 82 0 0 0 0 0 0 0 0 0 4 1 0 4 2 0 2 4 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10820() 11 4 3 9 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 3 5 0 16 8 17 3 3 2 8 6 12 10 3 2 2 1 0 17 16 0 1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG26185() 1 5 21 7 2 0 0 1 0 1 0 0 0 4 0 1 0 2 0 6 3 5 5 1 6 2 2 6 3 0 0 7 8 10 8 14 5 17 2 4 7 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG09934() 18 3 13 9 0 0 1 5 0 0 0 3 1 2 0 2 1 3 2 8 5 6 9 2 0 12 0 1 2 8 5 5 5 0 6 23 0 0 4 3 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 COG3930(Uncharacterized protein conserved in bacteria) 79 1 16 1 0 0 1 0 5 0 1 0 0 0 0 1 0 4 0 1 1 1 7 0 4 0 8 2 2 0 1 0 0 2 0 5 17 1 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3854(Uncharacterized protein conserved in bacteria) 14 6 17 5 2 4 1 0 0 0 0 0 0 1 0 0 0 10 0 1 5 3 4 1 0 10 0 0 0 3 0 9 1 0 2 2 0 35 34 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG22512(Transcriptional protein) 1 3 14 3 2 0 0 6 3 4 6 2 4 12 0 5 2 6 7 6 3 1 1 3 2 20 1 1 3 1 0 3 9 5 7 11 0 0 6 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3049(Penicillin V acylase and related amidases) 59 2 0 0 0 0 0 0 1 0 0 0 0 1 0 0 3 3 2 0 0 0 0 2 0 7 1 0 0 0 0 2 1 0 0 0 0 87 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12972() 16 2 2 11 2 3 2 0 0 0 0 0 1 0 0 0 0 0 0 3 13 5 15 4 14 0 2 8 9 9 8 8 2 0 2 2 0 14 8 2 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1571(Predicted DNA-binding protein containing a Zn-ribbon domain) 1 2 19 7 0 0 0 0 0 0 0 3 0 4 8 0 0 0 3 4 11 9 14 13 6 7 4 3 6 1 1 1 8 2 0 15 4 2 2 3 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG35687() 12 7 0 12 1 3 0 1 0 0 0 0 2 0 0 0 0 0 0 1 17 7 23 11 5 0 0 12 7 5 8 5 2 2 0 0 0 19 7 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG10766() 13 5 3 11 0 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 11 8 24 7 15 0 3 6 18 9 17 4 1 0 2 2 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG11571() 4 5 26 10 0 0 0 1 2 1 1 0 0 9 1 1 7 1 10 9 6 8 12 0 0 2 3 2 4 0 2 4 6 4 0 16 1 0 5 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG4963(Flp pilus assembly protein, ATPase CpaE) 119 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 6 1 0 0 0 0 1 0 0 3 0 0 0 0 0 0 0 0 0 0 7 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06349() 75 1 2 1 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 39 47 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15434(Transposase) 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 24 138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25847() 0 3 6 4 0 0 3 3 1 0 2 4 2 2 4 0 0 0 1 0 2 2 3 1 2 6 1 0 6 0 2 10 17 10 29 6 0 15 6 13 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG16081() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 19 1 0 1 0 0 1 0 47 2 0 1 0 0 0 1 1 2 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21314(Signal peptidase) 16 4 1 8 1 2 1 0 0 0 0 0 0 0 0 1 0 0 0 0 6 4 14 10 10 0 6 2 12 11 7 8 1 0 2 1 0 25 12 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG12984() 14 4 2 10 4 5 2 0 0 0 0 0 3 0 0 0 0 0 0 1 11 4 17 10 5 0 0 5 8 10 3 5 0 0 9 0 2 24 10 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4723(Phage-related protein, tail component) 21 1 2 4 1 1 1 9 1 0 2 4 8 0 2 1 5 4 2 1 1 0 2 2 0 1 2 0 4 5 9 3 4 0 7 0 0 53 2 0 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 NOG15892() 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 21 22 9 2 0 0 3 1 0 48 3 0 2 0 0 0 1 0 0 3 0 51 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG25386() 3 1 2 4 1 4 0 1 0 0 4 0 2 11 0 1 2 0 0 2 0 10 0 2 0 10 2 0 1 2 0 3 3 0 6 7 2 76 2 0 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG08753() 62 7 19 14 0 2 3 1 0 0 0 3 0 0 0 1 0 0 3 1 2 5 1 1 1 0 8 2 1 0 6 0 2 0 12 2 2 1 0 2 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13293() 4 8 15 3 1 1 0 3 0 4 4 1 0 2 0 3 12 4 1 1 3 3 8 2 2 7 1 0 1 4 0 0 1 2 5 5 5 50 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11251() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 25 20 1 0 0 0 0 0 0 57 0 0 0 0 0 0 0 0 0 0 0 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2219(Eukaryotic-type DNA primase, large subunit) 5 4 18 8 0 1 0 0 0 0 0 0 2 2 2 0 4 0 0 6 5 2 8 6 8 14 7 1 6 2 1 3 8 0 0 16 3 0 1 4 6 6 1 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG11621() 10 12 13 11 0 1 2 1 2 2 0 2 0 6 0 0 0 1 2 1 1 3 5 4 9 17 2 6 0 0 2 6 0 0 13 20 2 3 0 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG28850() 4 0 3 2 2 8 0 5 2 1 2 1 4 9 6 1 2 3 6 10 2 4 4 1 5 5 6 4 3 6 0 0 1 1 14 3 2 18 3 3 1 6 0 0 0 0 0 1 0 0 0 3 0 0 0 3 NOG16453(Photosystem I reaction center subunit psaK) 17 7 1 7 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 11 6 14 8 14 0 1 2 10 6 7 5 3 0 7 0 0 21 14 0 0 2 0 0 0 0 0 0 0 0 0 5 0 0 0 0 COG2362(D-aminopeptidase) 99 2 24 1 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 2 1 2 0 3 0 0 6 3 1 0 2 3 0 2 0 0 0 5 0 4 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG23360(Parallel beta-helix repeats) 0 3 6 2 4 0 5 3 3 2 0 0 0 2 2 0 0 0 0 1 5 9 4 3 6 3 1 0 3 3 5 7 6 8 38 3 0 11 2 12 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1964(Predicted Fe-S oxidoreductases) 6 9 19 10 0 2 1 0 0 2 0 1 0 0 6 0 0 5 1 1 0 1 2 1 1 17 3 1 1 2 0 3 9 2 0 19 16 22 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG3016(Uncharacterized iron-regulated protein) 9 2 3 5 0 3 0 2 0 2 0 0 0 8 2 3 7 1 2 2 0 0 2 2 2 7 1 0 1 0 0 4 1 0 0 4 13 75 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1465(Predicted alternative 3-dehydroquinate synthase) 1 8 18 2 0 0 0 0 0 0 0 0 2 2 0 1 0 1 0 5 5 3 12 9 2 6 0 6 4 1 2 4 8 7 0 15 4 2 7 10 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 12 NOG10066(Glycosyl transferase) 9 4 4 7 12 0 2 0 0 3 2 0 0 11 4 3 5 9 7 3 6 2 2 5 2 1 3 1 2 1 0 9 2 0 4 2 4 23 11 1 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG30848() 16 2 0 10 5 4 2 1 0 0 0 0 0 0 0 0 0 0 0 1 21 8 20 14 12 0 1 1 3 12 12 1 3 0 4 0 0 0 7 1 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG29208() 14 2 1 6 1 1 2 0 0 0 0 0 2 0 0 0 0 0 0 0 9 5 11 14 10 0 3 10 9 6 4 6 1 2 2 0 0 15 23 5 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG35914() 12 5 1 14 3 3 0 0 1 0 0 0 0 0 0 0 0 0 0 1 11 8 9 7 12 0 1 3 9 7 7 4 0 1 2 1 0 23 18 1 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG3101(Uncharacterized protein conserved in bacteria) 0 1 0 0 2 1 0 3 0 1 6 2 1 5 0 1 0 0 4 2 1 1 2 2 0 0 1 0 1 0 0 2 3 2 0 9 16 96 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3635(Predicted phosphoglycerate mutase, AP superfamily) 6 9 28 23 0 0 0 2 1 0 0 1 2 2 8 0 3 0 3 1 2 2 3 0 1 5 1 0 0 2 0 0 0 0 0 17 8 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10129() 0 2 2 4 1 1 1 0 3 5 0 0 5 2 0 2 0 2 1 4 6 5 4 4 0 0 0 2 3 0 0 13 8 8 8 2 0 35 8 15 1 2 0 0 0 0 0 0 0 0 0 7 0 0 0 2 NOG21643() 11 3 1 12 1 3 0 0 0 0 0 0 0 0 0 0 0 0 4 0 19 3 18 8 7 2 2 1 7 13 8 11 0 0 2 1 0 27 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19624() 104 0 3 1 0 0 0 0 0 0 0 1 0 4 0 0 2 8 1 0 0 0 3 3 0 7 4 0 1 0 1 0 6 0 2 6 5 3 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG13421() 31 6 4 10 0 0 4 8 3 3 5 1 0 9 4 1 1 0 6 3 0 2 2 4 0 0 6 0 2 2 0 8 3 1 6 9 15 2 4 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG33742() 4 1 2 5 0 0 1 3 1 2 2 0 1 10 0 0 0 0 1 3 1 3 7 1 0 0 1 0 3 0 4 9 10 19 16 9 0 26 6 12 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG19377() 3 0 0 0 0 0 0 4 2 0 3 0 0 2 0 4 4 1 4 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 131 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19698() 8 2 0 0 2 0 2 1 0 0 0 0 0 1 0 1 3 3 2 2 3 0 0 0 4 1 1 4 2 1 3 2 0 1 7 4 0 96 3 1 1 0 0 0 0 0 2 0 0 0 0 1 0 0 0 4 NOG11649() 1 0 0 3 0 0 8 3 6 2 5 3 4 1 0 4 1 1 7 2 0 0 1 0 1 3 7 6 1 0 0 9 7 4 24 17 10 9 2 8 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1859(RNA:NAD 2-phosphotransferase) 36 0 8 7 2 0 0 0 0 0 1 0 2 5 2 0 0 0 0 13 5 7 10 4 3 0 1 2 2 5 3 0 8 0 0 7 4 4 1 10 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 6 NOG30278() 8 23 15 14 0 3 13 5 0 3 0 0 0 2 0 0 0 0 0 1 3 1 9 3 3 0 0 2 2 3 2 7 5 3 17 5 0 0 3 9 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG09800(3-Hydroxyanthranilate 3,4-dioxygenase) 5 0 17 5 2 2 1 0 4 0 9 2 2 1 0 2 2 4 4 3 2 0 7 5 0 10 2 0 1 1 0 7 8 1 8 11 5 23 2 5 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08458() 13 1 3 5 2 5 1 0 0 3 0 0 0 0 0 0 0 0 0 0 13 5 10 8 14 0 0 2 9 7 10 7 1 3 4 1 0 29 11 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09940(DNA polymerase) 0 3 4 5 0 1 0 10 2 1 21 2 2 8 0 0 3 7 24 0 0 0 0 0 0 10 3 0 0 0 0 6 1 0 0 0 1 53 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04778() 19 0 1 1 0 0 0 0 0 0 0 0 0 0 0 5 0 8 0 0 2 0 0 0 0 6 0 2 0 2 0 1 0 0 2 2 7 106 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05960() 58 1 2 2 0 0 0 0 0 0 0 0 0 4 0 2 1 2 2 6 2 2 1 0 0 0 6 0 2 2 3 3 0 0 2 1 2 60 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4125(Predicted membrane protein) 160 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18451() 9 16 8 10 0 1 2 3 0 0 0 1 2 0 2 1 3 3 0 6 0 2 4 2 2 3 2 0 6 2 5 5 3 2 8 24 10 5 2 1 5 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG16401() 8 2 1 16 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 2 15 4 14 17 16 0 0 4 4 8 9 6 0 1 0 0 0 18 16 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG16518() 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 12 22 2 0 2 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22687() 8 9 4 6 0 1 4 1 1 1 0 1 2 0 2 1 6 19 1 2 4 2 2 6 1 0 4 5 4 0 6 8 1 10 10 5 4 0 4 4 0 5 0 0 0 0 0 0 0 0 0 4 0 0 0 9 COG2922(Uncharacterized protein conserved in bacteria) 35 10 14 3 0 0 0 1 0 3 0 6 2 11 5 3 7 6 7 1 1 1 1 0 0 9 0 0 1 0 0 1 0 2 3 12 14 5 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG36760() 0 6 4 1 0 1 0 4 5 2 6 0 0 2 0 0 0 0 4 2 12 5 14 5 5 34 1 2 3 7 0 3 5 4 2 5 1 0 12 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 NOG16382(Photosystem II reaction center protein) 4 2 7 15 2 4 2 0 0 0 0 0 0 0 0 0 0 0 2 1 5 6 18 9 16 0 0 3 3 13 6 3 1 0 2 1 0 19 18 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 0 1 NOG11383() 2 7 10 5 1 0 1 5 0 0 0 1 0 3 0 1 2 0 1 3 0 1 7 2 5 1 2 4 2 0 3 4 2 0 6 0 3 65 1 7 2 1 0 0 0 0 0 0 0 0 0 5 1 0 0 1 NOG10855() 35 0 0 0 1 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4223(Uncharacterized protein conserved in bacteria) 2 3 2 1 0 0 0 0 0 0 4 0 1 12 4 0 0 0 4 1 0 1 1 2 0 1 3 4 3 1 2 8 7 8 18 10 5 24 6 15 4 8 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG19498() 8 3 1 6 0 3 0 0 0 1 0 0 0 0 0 0 0 0 1 1 19 6 14 12 6 0 2 3 8 12 9 6 2 0 2 0 2 22 6 2 1 0 0 0 0 0 0 0 0 0 0 8 0 1 0 0 NOG37939() 7 4 0 3 0 3 0 0 0 0 0 0 0 0 0 0 0 0 1 3 7 2 12 12 14 0 2 1 5 17 16 13 4 0 1 0 0 17 18 0 1 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 NOG33567() 0 6 8 5 2 0 2 0 0 0 0 0 0 45 71 0 2 1 0 1 1 0 1 8 0 0 4 2 0 0 0 0 0 0 0 5 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2604(Uncharacterized protein conserved in bacteria) 64 6 2 0 0 1 2 4 0 0 0 0 0 2 0 2 2 2 0 1 0 4 1 2 0 0 0 1 1 1 2 7 3 2 2 2 17 29 0 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG10740() 14 2 1 8 0 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 14 4 13 6 13 0 6 2 11 5 13 5 4 0 2 0 0 19 15 3 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 NOG11542() 4 2 0 0 0 0 0 2 6 7 4 1 1 5 0 1 0 0 5 0 0 0 2 0 1 0 0 0 2 1 0 1 0 0 2 0 12 104 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17168() 31 4 1 0 1 0 0 5 2 2 5 1 3 1 6 4 0 0 3 1 2 0 1 1 0 0 2 0 0 0 0 2 1 2 2 0 9 72 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1890(Ribosomal protein S3AE) 0 4 20 2 1 1 0 0 0 0 0 1 2 6 4 1 0 0 0 2 10 7 13 3 5 7 0 1 4 4 1 5 4 12 0 6 14 0 2 7 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG12841() 13 4 6 9 2 3 4 0 0 1 0 0 0 0 0 0 0 0 0 0 5 2 16 8 4 0 0 5 4 7 12 8 4 0 5 1 0 22 15 3 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 1 NOG19794() 15 5 2 14 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 12 13 5 14 0 0 5 4 4 10 5 0 0 2 0 0 25 12 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG3719(Ribonuclease I) 104 1 3 2 0 1 0 0 1 2 0 3 0 1 2 2 2 2 2 2 2 0 3 1 2 3 0 4 0 0 3 0 0 0 0 4 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20201() 2 6 3 9 0 1 3 18 3 2 0 2 0 2 4 1 4 3 6 5 4 1 4 2 1 3 3 5 1 0 3 9 6 5 15 10 0 1 2 7 3 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG25695() 3 2 28 4 2 0 4 5 1 2 0 0 1 4 0 1 0 4 4 4 2 2 5 1 2 4 0 5 1 0 0 14 5 13 12 11 0 0 3 11 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG19134() 1 4 4 2 3 1 2 2 3 1 0 2 0 0 0 0 2 25 1 2 3 2 4 6 1 8 8 4 1 1 4 6 3 1 15 15 0 4 5 12 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG1019(Predicted nucleotidyltransferase) 1 6 17 2 0 2 0 2 0 0 0 0 0 0 5 3 0 0 1 2 3 8 8 9 2 14 7 8 5 3 1 7 6 0 0 10 10 3 9 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG31683() 13 4 0 11 1 3 1 0 0 0 0 0 1 0 0 0 0 0 0 3 7 2 14 9 12 1 1 6 6 10 13 11 4 0 3 0 0 20 7 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1827(Predicted small molecule binding protein (contains 3H domain)) 48 2 11 4 2 0 0 0 2 0 0 0 0 5 0 1 6 7 1 1 0 0 1 0 2 0 4 0 3 0 1 2 2 0 4 4 0 48 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20549(Nickel ion transporter protein) 17 5 4 6 2 3 1 0 0 0 0 0 0 2 0 0 0 0 0 0 12 5 17 10 11 0 3 2 9 14 17 3 2 1 0 0 0 0 17 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 NOG10884(Protein Rv2267c) 8 0 6 3 3 1 0 0 0 0 1 0 1 2 0 0 6 0 4 0 2 5 2 1 0 1 0 5 1 2 3 8 2 2 4 22 2 41 15 7 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05959() 51 1 35 10 2 0 0 0 0 0 0 1 0 9 0 1 0 0 1 1 0 6 1 1 1 2 1 4 6 0 2 1 2 2 2 9 0 2 2 3 1 1 2 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG18953() 2 5 0 4 0 0 3 0 1 2 3 0 0 4 0 3 2 0 2 1 6 0 5 3 3 0 4 2 2 1 2 1 3 1 6 0 2 88 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12895() 17 3 2 9 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 5 12 9 3 0 4 0 10 7 17 13 0 1 6 0 0 22 8 2 0 2 0 0 0 0 0 0 0 0 2 4 0 0 0 0 COG3619(Predicted membrane protein) 152 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10087() 153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15859(Cytochrome c oxidase polypeptide IV) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 19 3 0 0 0 0 0 0 61 0 0 0 0 0 1 0 0 0 0 0 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2824(Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism) 87 8 2 2 0 0 0 0 0 0 2 3 2 5 2 2 3 12 4 0 0 0 2 2 1 5 2 0 0 0 1 0 0 1 2 1 10 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19844() 9 9 1 8 1 1 2 0 0 0 0 0 0 0 0 0 0 0 1 5 9 6 9 10 16 0 1 6 8 7 3 8 2 1 2 1 0 24 12 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG30721() 2 8 8 4 1 0 2 0 0 3 1 1 2 4 6 1 1 5 0 0 5 7 6 2 2 20 2 1 6 0 3 5 3 0 6 27 2 6 2 4 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4645(Uncharacterized protein conserved in bacteria) 117 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06477() 164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29413() 160 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20034() 94 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 1 0 0 2 0 2 53 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27918() 0 4 1 3 1 3 3 10 0 1 3 0 4 16 2 4 0 0 5 1 3 6 4 5 1 5 9 1 0 1 2 4 2 2 2 5 1 37 1 3 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG13266() 159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08869() 5 1 2 3 0 2 1 3 0 1 1 0 2 7 0 1 0 0 3 4 6 7 3 5 2 0 2 4 1 0 2 12 6 11 15 14 0 14 6 6 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG4425(Predicted membrane protein) 0 0 0 0 0 0 0 1 0 0 0 1 0 3 2 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 0 1 0 0 151 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1803(Methylglyoxal synthase) 47 3 9 4 2 1 0 0 1 0 2 1 0 2 0 5 8 10 2 2 0 3 2 0 0 20 0 0 2 2 0 6 1 0 2 1 0 23 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG18934() 2 4 5 2 0 1 1 1 1 0 0 5 2 9 4 2 10 4 4 7 2 3 3 6 4 14 1 7 0 0 1 7 3 4 2 7 7 10 3 6 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06048() 3 2 4 1 0 0 0 0 4 0 0 1 0 6 0 2 0 0 11 1 2 2 2 0 0 1 0 0 2 0 2 0 0 2 2 3 2 108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19100() 1 4 49 3 1 0 0 0 1 0 1 0 0 4 6 2 3 0 5 2 6 6 6 6 2 0 7 5 1 1 3 2 1 0 6 16 0 5 0 2 1 3 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG14590(High potential iron-sulfur protein) 114 4 0 0 1 0 0 0 0 0 0 0 3 0 0 0 10 3 0 0 0 0 0 1 2 3 0 0 0 0 0 0 0 0 0 0 0 19 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16536() 11 6 2 8 2 1 2 0 0 0 0 0 0 0 0 0 0 0 1 0 17 6 13 6 16 0 1 1 6 13 10 5 0 0 3 1 0 12 16 0 0 0 0 0 0 0 0 0 1 0 0 3 0 0 0 0 NOG18993() 0 2 0 6 0 0 0 7 1 1 0 0 0 1 0 1 0 0 6 0 1 1 0 3 2 0 0 0 0 0 0 1 0 0 0 6 10 112 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09833() 159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1965(Protein implicated in iron transport, frataxin homolog) 79 1 4 0 0 1 1 0 4 4 2 0 1 4 0 2 6 3 1 2 1 0 1 3 0 4 2 1 3 0 1 6 1 0 4 0 10 8 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1781(Aspartate carbamoyltransferase, regulatory subunit) 5 4 22 5 0 0 0 0 0 1 0 1 0 4 12 0 0 0 0 6 14 5 7 3 1 9 1 4 2 3 2 7 3 0 0 14 7 0 1 2 5 2 0 0 0 0 0 0 0 0 0 3 0 0 0 8 NOG06374() 151 0 1 0 0 0 0 0 0 0 0 0 0 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19090() 3 0 1 3 0 1 0 0 0 0 2 0 0 0 0 0 1 0 3 0 2 6 19 4 8 2 1 5 18 12 6 11 0 4 7 0 1 19 15 0 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG1427(Predicted periplasmic solute-binding protein) 1 2 9 0 0 0 0 1 0 0 0 0 4 2 1 0 2 0 1 10 2 3 3 2 1 16 3 4 0 1 0 5 14 2 2 10 6 21 3 12 8 7 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG3297(Type II secretory pathway, component PulL) 80 4 5 1 1 0 3 4 0 0 6 0 0 5 2 1 2 0 1 0 2 0 2 4 4 4 1 1 0 1 4 3 0 0 0 0 2 16 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG36286() 0 0 8 0 1 3 0 0 0 0 0 0 0 2 0 0 2 0 0 0 1 10 0 4 0 0 3 11 4 1 10 21 20 3 0 12 0 1 8 14 5 0 0 0 0 0 0 0 0 0 0 2 0 0 0 16 COG2091(Phosphopantetheinyl transferase) 95 1 3 2 2 1 0 0 0 0 0 2 2 8 0 2 0 0 1 0 0 1 2 0 1 1 1 0 0 1 0 0 0 0 0 5 3 26 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3166(Tfp pilus assembly protein PilN) 51 5 2 2 0 2 0 0 2 0 4 2 2 6 7 1 2 2 4 2 0 4 2 1 0 1 1 0 0 0 2 0 0 2 0 3 11 37 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12875() 13 0 3 10 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 4 7 8 14 12 17 0 0 3 3 8 5 17 4 0 5 0 0 16 7 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1632(Ribosomal protein L15E) 2 3 13 4 0 0 0 0 0 0 0 1 0 4 5 0 2 0 3 5 9 9 8 4 3 5 4 0 4 4 1 5 6 7 0 5 18 2 4 2 6 4 0 0 0 0 0 0 0 0 0 2 0 0 0 8 NOG06537() 64 8 3 0 0 0 0 0 2 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3148(Uncharacterized conserved protein) 103 4 3 0 0 0 0 0 0 0 1 0 0 1 0 1 1 3 1 0 0 2 4 2 2 4 1 0 1 2 0 0 0 0 0 0 25 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1031(Uncharacterized Fe-S oxidoreductase) 0 1 4 1 0 0 0 0 0 0 0 5 0 0 6 0 2 0 3 13 13 8 10 1 0 0 1 4 4 0 0 15 11 4 0 7 9 0 0 8 5 4 0 0 0 0 0 0 0 0 0 2 0 0 0 21 NOG21759() 0 5 14 7 3 2 3 4 0 0 1 5 2 13 1 1 0 1 3 5 1 1 2 2 8 1 6 10 3 1 0 11 4 4 6 16 2 0 6 2 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG18946() 5 8 8 8 2 4 4 3 0 2 3 0 1 15 2 4 0 0 1 0 2 0 6 4 6 0 8 3 1 1 2 8 6 4 4 9 0 0 6 9 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 8 COG4702(Uncharacterized conserved protein) 78 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 26 9 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2016(Predicted RNA-binding protein (contains PUA domain)) 7 9 19 1 0 1 0 0 0 0 0 2 0 7 3 0 0 2 1 9 6 8 8 3 4 2 2 2 4 3 0 7 5 9 0 6 4 2 2 6 4 5 0 0 0 0 0 0 0 0 0 4 0 0 0 4 COG3963(Phospholipid N-methyltransferase) 88 2 6 2 2 0 0 0 0 0 0 0 0 3 1 0 2 2 1 2 2 1 2 0 0 1 1 0 1 0 1 4 1 2 5 9 0 10 0 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3667(Uncharacterized protein involved in copper resistance) 66 12 6 2 5 1 0 0 0 0 0 1 0 11 3 0 2 0 0 2 0 1 0 1 0 0 4 1 1 2 0 0 0 0 0 0 11 27 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG23844(Cytochrome c protein) 3 1 4 2 0 0 1 1 2 1 0 0 3 2 1 0 0 0 1 3 2 0 3 1 2 0 10 2 2 0 4 10 7 11 24 8 2 10 7 11 2 9 0 0 0 0 0 0 0 0 0 4 0 0 0 5 NOG08037(Dioxygenase) 108 0 8 4 0 0 0 0 0 0 0 1 0 4 0 1 2 0 1 2 0 0 0 0 1 2 3 0 0 0 2 0 0 0 3 4 12 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27133() 0 0 0 0 3 0 6 9 6 4 1 2 4 0 4 0 0 0 2 5 6 0 0 1 0 0 3 5 1 1 0 11 2 4 27 17 1 0 7 19 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33819() 15 6 2 13 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 11 3 15 13 8 0 5 2 4 3 13 8 1 2 6 2 0 15 7 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08767(Secretory lipase) 83 0 2 1 0 0 0 1 0 0 2 0 0 1 0 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5447(Uncharacterized conserved protein) 4 1 4 1 0 2 0 7 1 2 7 1 0 13 0 2 0 1 4 1 4 0 1 0 2 0 2 2 2 0 0 4 10 11 6 6 4 20 3 16 6 5 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG16204() 14 5 1 10 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 6 9 12 6 15 6 1 0 10 9 12 10 2 2 0 4 0 14 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 NOG08870() 0 0 1 4 0 1 2 5 1 0 0 0 8 8 0 0 0 0 2 1 0 0 2 1 0 0 3 8 2 0 0 12 9 4 27 8 3 20 2 15 3 3 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG2910(Putative NADH-flavin reductase) 89 0 4 2 0 0 0 2 0 2 0 0 0 2 0 1 0 0 1 0 0 0 0 0 0 4 2 0 0 2 0 0 0 0 0 2 1 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35638() 11 7 1 12 0 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 14 8 19 4 18 3 0 2 8 13 6 3 0 0 4 2 0 0 18 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 3 NOG10758() 17 2 2 14 4 3 1 0 0 0 0 0 0 1 0 0 0 0 0 0 12 1 12 11 12 0 2 2 8 5 13 4 2 0 1 2 0 13 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17150() 29 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 4 3 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 14 103 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2996(Uncharacterized protein conserved in bacteria) 49 1 1 0 0 0 0 5 2 5 8 3 5 3 0 4 4 5 4 1 0 5 0 3 1 2 1 0 0 2 0 5 1 0 10 8 15 0 0 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG16323() 2 2 2 11 2 2 1 0 2 1 3 4 7 15 0 1 3 0 12 4 4 3 7 7 1 0 8 0 5 3 0 5 2 5 2 9 4 4 0 3 2 6 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG16861(Transcriptional regulator protein) 2 0 1 1 10 1 4 3 5 0 2 1 3 0 2 1 0 3 4 2 0 6 4 1 5 8 2 8 1 0 0 6 6 9 15 14 0 5 4 12 5 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG12959() 31 6 0 14 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 10 5 14 9 7 0 1 4 5 7 6 6 1 2 0 0 0 5 22 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG0700(Uncharacterized membrane protein) 61 2 19 2 1 3 0 0 1 1 0 1 0 1 2 1 3 3 3 3 3 2 4 2 8 8 3 5 1 0 1 3 6 0 0 0 2 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5253(Phosphatidylinositol-4-phosphate 5-kinase) 4 6 21 9 3 13 3 2 0 0 0 0 8 0 4 2 0 0 0 0 9 9 6 4 7 0 6 7 2 7 0 0 2 0 1 13 0 0 3 4 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2039(Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)) 2 0 2 1 1 1 0 0 0 0 0 2 2 2 2 1 8 15 0 8 2 6 4 1 4 49 3 4 2 0 4 3 1 0 0 2 4 8 3 2 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG14730(Regulator protein) 0 2 2 3 2 0 1 2 2 0 3 3 1 11 0 5 0 0 4 1 0 0 0 4 1 0 8 1 1 0 2 11 4 12 20 8 1 23 3 14 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3463(Predicted membrane protein) 12 2 4 4 0 4 1 4 0 0 0 0 0 0 0 0 6 7 1 1 3 0 2 2 0 16 4 0 0 2 2 17 4 0 2 19 8 22 10 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16535() 13 1 3 10 0 2 1 1 0 0 0 0 1 0 0 0 0 0 0 1 12 5 14 9 9 0 1 3 6 10 9 6 2 2 3 0 0 19 12 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 COG2354(Uncharacterized protein conserved in bacteria) 45 7 1 1 6 0 0 0 1 2 2 0 0 0 0 2 3 0 5 0 0 0 5 0 1 4 2 0 0 1 0 1 2 0 0 4 0 59 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08779(Parallel beta-helix repeat protein) 1 4 24 3 1 2 0 2 0 2 0 0 0 5 0 0 0 0 0 6 5 12 9 1 0 0 7 4 5 1 9 4 5 4 5 6 2 2 4 6 4 1 0 0 0 0 0 0 0 1 0 2 0 0 0 11 COG1613(ABC-type sulfate transport system, periplasmic component) 132 0 1 0 0 0 0 0 0 0 0 0 3 0 0 0 5 9 0 0 1 0 0 1 0 4 0 0 1 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30670() 13 4 1 7 1 3 1 0 0 0 0 0 2 0 0 0 0 0 0 2 13 0 7 8 12 1 3 2 8 10 13 13 2 2 2 1 0 15 9 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG13363(Type IV secretion system protein) 159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09625() 19 2 0 0 0 1 0 0 0 0 0 0 0 4 0 0 0 0 0 1 2 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23368() 3 6 5 1 8 1 5 0 1 2 7 5 0 9 6 1 0 3 2 5 1 0 8 1 3 0 3 2 3 0 2 10 8 0 13 11 0 6 4 7 3 1 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG12789() 14 4 3 11 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 3 14 6 24 6 10 0 5 2 8 8 8 3 2 0 8 0 0 8 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33963() 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 1 4 2 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10847() 10 2 0 9 2 3 1 0 0 0 0 0 0 0 0 0 2 0 0 0 12 12 25 13 15 0 2 1 4 16 8 8 0 0 3 0 0 0 7 1 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG10567() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 15 13 2 0 0 0 1 0 0 29 0 0 0 0 0 1 1 0 0 0 0 94 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18156() 159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06321() 130 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19158() 0 2 7 2 1 0 1 4 1 0 3 1 3 3 2 1 1 4 0 3 4 8 4 1 2 1 1 3 5 1 4 10 4 6 19 20 0 5 6 7 2 5 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG16414(UPF0367 protein) 10 0 0 7 0 8 1 0 0 0 0 0 0 0 0 0 0 0 1 0 10 5 11 23 9 0 3 5 7 13 6 8 0 0 2 1 0 12 10 3 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG04718() 156 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2105(Uncharacterized conserved protein) 7 4 8 2 1 0 1 0 1 0 2 1 3 0 2 1 8 3 0 0 6 2 9 9 3 23 4 2 2 2 0 3 4 2 0 2 4 29 2 0 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG4192(Signal transduction histidine kinase regulating phosphoglycerate transport system) 41 2 2 5 0 0 3 5 1 1 3 5 0 3 0 1 1 2 0 0 2 0 4 1 0 0 0 0 0 0 4 0 0 6 0 2 9 40 10 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3940(Predicted beta-xylosidase) 133 0 1 0 1 0 0 0 0 2 0 0 3 0 0 0 0 0 0 0 0 0 0 1 3 0 0 1 0 0 0 3 2 0 4 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4779(ABC-type enterobactin transport system, permease component) 155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2943(Membrane glycosyltransferase) 99 6 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 2 2 0 0 0 1 0 0 1 0 0 2 1 0 0 0 0 0 2 2 34 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26387() 1 5 0 4 0 2 2 1 0 0 5 0 1 2 0 1 0 7 0 2 2 0 4 2 2 23 10 9 1 1 4 1 3 8 10 6 2 22 4 4 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG07934(Malonate transporter protein) 64 3 13 3 0 0 0 1 0 0 0 0 4 4 2 0 0 1 3 6 3 0 5 0 1 2 0 1 2 2 0 3 1 2 2 20 0 0 6 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG07683() 20 3 0 7 0 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 5 11 8 13 9 0 1 2 1 9 7 3 1 1 0 2 0 24 14 2 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 COG3311(Predicted transcriptional regulator) 31 6 8 11 1 2 0 0 1 0 1 0 1 4 0 0 1 2 1 2 9 2 6 5 6 2 3 4 2 1 2 3 3 0 0 1 1 23 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 COG4087(Soluble P-type ATPase) 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 2 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3516(Uncharacterized protein conserved in bacteria) 100 2 0 2 0 1 1 0 0 0 0 0 0 6 0 0 3 0 0 0 0 0 2 0 0 3 1 0 0 0 2 1 0 0 0 1 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16562() 14 3 1 16 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 2 7 3 7 9 13 0 1 2 9 20 13 3 4 0 5 0 0 0 15 2 0 0 0 0 0 0 0 0 0 0 0 3 0 2 0 0 COG5500(Predicted integral membrane protein) 38 4 3 4 1 1 0 0 0 0 0 0 0 3 2 1 1 0 3 9 7 1 2 1 5 0 4 4 1 0 0 11 1 3 6 3 1 19 3 5 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG19780() 11 5 0 10 2 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 9 1 15 8 11 0 0 0 3 7 12 7 1 1 0 0 0 22 23 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG16080() 9 8 18 9 0 0 1 0 3 4 0 0 0 1 0 0 0 0 0 5 0 1 12 1 3 0 1 1 6 0 6 1 0 2 21 9 0 20 2 6 1 2 0 0 0 0 0 1 0 0 0 3 0 0 0 1 COG1041(Predicted DNA modification methylase) 0 2 7 3 0 2 0 0 0 1 0 4 0 0 2 1 0 0 1 4 3 7 11 2 2 15 2 4 5 4 4 12 6 2 2 3 18 4 0 5 7 4 0 0 0 0 0 0 0 0 0 3 0 0 0 6 NOG31922() 12 4 0 6 2 3 2 0 0 1 0 0 0 0 0 0 0 0 1 1 8 5 15 10 10 0 0 5 3 10 12 10 1 0 0 0 0 26 10 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5042(Purine nucleoside permease) 73 10 1 5 0 0 0 2 0 2 1 3 2 2 0 1 0 2 7 2 2 0 6 0 0 0 0 0 2 1 2 3 0 0 0 4 0 23 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19068() 0 2 1 1 1 0 1 5 2 3 3 2 2 2 0 0 2 2 1 1 6 4 14 4 0 1 3 2 3 0 2 3 4 4 4 7 0 48 5 4 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG12918() 13 4 2 4 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 10 5 12 7 9 0 2 2 10 9 7 3 3 0 2 0 0 28 19 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG32658() 14 3 1 8 1 6 0 0 0 2 0 0 0 0 0 0 0 0 1 0 6 3 12 8 14 0 0 2 6 16 8 7 2 1 0 0 0 25 10 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG26198() 1 3 2 7 6 0 3 3 1 0 3 2 0 2 0 0 2 0 3 2 0 0 0 3 0 3 1 6 0 0 2 6 5 6 42 8 6 2 3 7 2 2 0 0 0 0 0 0 0 0 0 6 0 0 0 7 NOG10772() 13 4 1 7 3 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 5 18 6 15 0 0 3 6 6 12 11 3 0 2 0 0 17 11 0 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 COG3375(Uncharacterized conserved protein) 1 0 2 0 0 0 0 0 0 0 0 0 0 4 0 0 8 10 0 1 2 1 1 0 0 39 3 0 0 0 0 0 1 0 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG23953() 1 4 17 3 0 3 1 4 21 6 24 0 6 3 3 0 6 0 8 4 2 4 5 2 2 1 2 0 2 4 0 1 3 2 0 7 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG19315() 3 2 10 1 2 2 1 0 0 0 1 1 0 4 0 2 0 1 0 2 2 0 2 2 2 14 3 1 0 1 0 11 6 13 23 7 0 7 14 10 2 1 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG16572() 26 2 2 12 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 1 13 7 6 1 3 6 5 6 7 4 0 0 4 0 0 18 11 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 0 0 COG2720(Uncharacterized vancomycin resistance protein) 1 1 4 2 0 1 0 0 2 0 0 0 0 1 0 1 7 4 1 2 0 3 4 0 0 10 0 0 0 0 0 4 0 0 2 9 9 81 2 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG0680(Ni,Fe-hydrogenase maturation factor) 49 3 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 7 90 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3240(Phospholipase/lecithinase/hemolysin) 68 0 1 0 1 1 0 1 0 3 0 1 0 8 0 1 2 4 3 0 0 0 0 2 3 0 1 1 0 1 0 5 11 8 1 3 2 9 3 4 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16447() 10 3 1 7 4 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 13 3 11 6 22 0 3 1 6 10 7 6 3 0 6 2 0 22 6 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG17738() 144 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 5 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1727(Ribosomal protein L18E) 3 1 12 4 1 2 0 0 0 0 0 1 1 3 2 1 2 1 1 8 11 7 10 6 0 5 0 5 4 1 0 5 1 3 0 6 22 3 2 4 4 8 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG1358(Ribosomal protein HS6-type (S12/L30/L7a)) 1 4 13 9 1 2 0 0 0 2 0 0 0 1 9 1 1 0 0 4 5 5 5 2 2 9 8 2 0 5 0 5 8 5 0 6 17 6 1 5 6 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG06252() 17 7 12 10 0 1 0 0 1 2 0 2 1 12 0 3 1 3 4 4 2 3 9 9 4 3 11 4 3 1 0 1 2 0 4 2 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG10009(Extracellular elastinolytic metalloproteinase) 4 0 2 0 5 1 3 2 2 2 6 0 0 2 4 5 4 1 6 3 0 0 4 4 8 2 2 0 0 1 0 15 1 6 9 18 0 10 4 3 6 6 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG3232(5-carboxymethyl-2-hydroxymuconate isomerase) 68 2 5 2 0 3 0 1 0 0 2 1 0 3 4 0 2 1 1 1 0 0 2 2 1 1 2 0 0 1 0 5 4 2 6 13 6 7 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG32991() 1 14 19 5 1 0 1 2 0 1 0 0 3 2 4 0 2 0 0 4 5 12 15 5 9 6 5 3 2 1 2 2 0 2 3 5 2 13 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG12785(Photosystem II reaction center W protein) 15 4 5 6 0 5 1 0 0 4 0 0 0 0 0 0 0 0 1 0 8 1 18 7 10 0 0 7 3 12 7 6 3 2 0 1 0 22 4 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11404() 1 0 0 2 7 0 3 1 6 4 3 1 0 3 4 0 3 6 5 2 0 2 2 3 4 3 0 3 2 3 2 7 3 4 18 12 4 8 4 11 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG2342(Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase) 124 5 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 1 0 0 2 4 11 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4757(Predicted alpha/beta hydrolase) 133 4 1 2 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 1 0 0 0 1 1 0 0 0 4 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25098(Protein involved in bacterial chemotaxis) 140 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3795(Uncharacterized protein conserved in bacteria) 129 0 2 0 2 0 0 0 0 2 0 0 0 0 0 0 8 2 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1784(Predicted membrane protein) 0 0 2 0 0 0 0 0 0 0 1 4 0 5 0 2 6 0 0 4 7 8 11 3 11 2 9 6 3 1 0 2 8 1 2 7 18 2 0 3 12 6 0 0 2 0 0 0 0 0 0 0 0 0 0 7 NOG08782() 63 5 34 6 0 0 1 0 0 0 0 0 1 0 0 0 0 1 0 3 3 7 3 5 1 0 0 3 1 0 4 0 1 0 2 0 0 0 2 3 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1976(Translation initiation factor 6 (eIF-6)) 1 7 9 8 1 1 0 0 0 0 0 2 0 0 5 0 1 0 0 9 7 15 4 5 4 6 7 1 1 1 0 4 9 1 0 10 5 3 1 2 1 11 0 0 0 0 0 0 0 0 0 1 0 0 0 11 COG0257(Ribosomal protein L36) 9 6 6 2 0 0 3 0 0 2 0 1 0 14 0 0 1 3 2 3 0 2 2 3 0 12 0 5 2 2 0 4 4 2 4 14 0 30 8 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG29086() 12 2 2 10 3 3 0 3 1 0 0 0 0 0 0 0 0 0 0 1 9 2 9 10 16 0 2 3 6 17 8 5 1 0 2 2 0 12 11 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG10085(Prolyl 4-hydroxylase, alpha subunit) 7 1 16 0 3 4 0 5 10 4 0 1 9 10 0 4 5 4 9 21 2 0 1 1 5 10 0 6 0 2 0 2 2 4 0 3 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3730(Phosphotransferase system sorbitol-specific component IIC) 13 4 3 10 0 0 5 2 1 0 0 1 2 9 5 6 2 5 3 2 7 5 4 3 0 2 4 3 4 0 0 3 7 1 2 23 1 0 3 0 4 1 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG16302(Glycosyl transferase, group 1) 6 4 4 4 0 0 4 2 0 0 0 6 0 3 0 2 4 5 5 6 18 4 6 3 2 0 0 5 3 2 7 4 3 6 8 6 3 7 4 2 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG12860() 9 4 0 9 4 1 0 2 0 0 0 0 0 0 0 0 0 0 1 1 16 2 8 8 3 0 2 3 10 6 12 8 1 5 3 1 0 13 17 0 1 1 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG12823() 9 0 1 10 0 4 0 0 0 2 0 0 0 0 0 0 0 0 0 1 12 0 22 10 15 2 1 3 2 6 13 7 2 0 0 0 0 14 9 4 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3070(Regulator of competence-specific genes) 62 1 3 0 1 1 0 0 0 1 2 0 0 4 0 6 4 4 2 0 0 2 3 3 0 6 2 1 0 2 2 3 1 0 2 3 4 23 3 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3310(Uncharacterized protein conserved in bacteria) 87 4 3 0 0 0 1 8 1 1 3 1 1 8 2 2 3 3 3 0 0 0 0 0 0 7 0 3 3 0 0 0 0 2 0 0 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12836() 8 5 1 2 0 2 1 0 0 1 0 0 0 2 0 0 0 0 0 0 10 6 14 8 12 0 1 3 12 10 11 3 2 0 4 0 0 24 6 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG10632() 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 2 26 2 1 2 2 0 1 3 59 0 0 0 0 0 0 0 0 0 1 0 49 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG0269(3-hexulose-6-phosphate synthase and related proteins) 3 3 11 1 0 0 0 5 0 2 1 0 8 13 4 4 6 8 7 1 0 0 2 0 0 31 4 1 5 1 1 2 0 2 5 5 4 7 2 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG30690() 0 1 0 1 0 0 0 0 0 2 3 0 2 4 0 0 0 0 10 0 1 1 2 0 0 1 9 0 1 1 0 4 3 0 2 1 0 102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13741(Cytochrome b protein) 2 3 21 2 0 3 0 0 0 0 3 0 0 2 3 2 5 14 1 2 2 6 1 2 5 42 0 0 0 0 0 1 0 0 2 14 5 6 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG09495() 0 0 1 0 0 0 0 2 0 3 0 2 0 0 0 0 0 0 1 3 6 4 0 10 1 0 3 0 1 1 0 9 9 2 2 15 2 33 3 6 8 2 0 0 0 0 0 0 0 0 0 1 0 0 0 23 NOG17318() 44 10 2 6 2 0 3 0 1 1 3 3 3 0 0 1 6 2 1 3 0 4 2 2 3 1 4 4 2 2 1 4 2 2 8 9 4 1 3 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG16591() 14 6 1 12 2 2 0 1 0 0 0 0 0 0 0 0 0 0 0 3 13 7 10 6 15 0 2 3 7 13 10 5 1 0 4 1 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 1 0 3 2 4 NOG31313() 6 3 0 8 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 9 4 14 13 15 0 2 0 11 11 14 13 2 1 1 0 0 15 4 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08502() 56 0 1 2 0 0 0 5 0 8 1 0 0 4 0 3 4 0 4 2 0 0 2 2 1 2 3 2 1 0 1 4 2 0 9 6 0 11 2 7 1 2 0 0 0 0 0 0 0 0 0 1 0 0 1 3 NOG34131() 5 2 0 4 0 0 1 3 3 7 1 6 0 8 4 0 4 4 4 5 3 0 0 2 1 0 1 0 0 1 0 1 2 12 16 7 2 36 2 2 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 COG1787(Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes) 7 4 6 7 2 6 0 0 0 0 0 0 0 2 0 1 0 0 0 2 11 6 14 11 15 0 0 0 7 12 15 2 2 0 9 1 2 2 2 0 0 2 0 0 0 0 0 0 0 0 0 1 0 1 0 0 NOG10813() 18 1 1 12 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 2 14 7 12 17 6 0 2 0 9 4 11 7 2 2 4 3 0 0 10 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 NOG31027() 14 4 0 8 1 1 4 0 0 0 0 0 0 0 0 0 0 0 0 4 13 7 15 5 4 0 0 4 4 7 9 5 1 1 0 0 0 14 22 0 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG09929() 114 2 4 5 1 1 1 0 0 0 0 0 0 2 0 0 0 4 1 2 2 0 2 2 0 2 1 2 1 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1237(Metal-dependent hydrolases of the beta-lactamase superfamily II) 14 15 8 9 1 0 4 1 0 3 0 0 0 2 0 5 1 0 1 3 0 3 9 3 3 1 3 5 2 1 4 3 2 1 10 13 1 12 0 6 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG15427(CDS, cytoplasmic protein family member) 5 1 4 6 2 1 2 8 1 0 2 1 3 0 4 0 2 7 1 6 4 7 6 1 0 17 1 7 4 1 1 2 6 2 6 10 3 3 4 4 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG24190() 6 3 2 12 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 18 4 25 9 12 0 1 4 8 8 14 8 2 2 2 0 0 0 4 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG21015() 11 5 0 8 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 14 4 10 10 14 0 3 2 7 5 15 6 2 1 0 0 0 18 8 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG23432() 1 0 0 1 0 0 0 4 0 2 0 0 0 0 0 0 0 0 3 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG09643(Major facilitator superfamily protein) 151 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38117(Phosphoribosyltransferase) 18 1 0 11 1 4 1 1 0 3 1 0 2 0 0 0 1 0 2 0 7 2 19 14 12 1 3 3 8 12 11 1 1 0 2 0 1 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 COG4641(Uncharacterized protein conserved in bacteria) 24 3 8 4 0 3 0 4 0 3 0 4 0 0 4 3 4 6 4 5 3 1 5 1 3 4 2 8 3 0 2 2 3 0 4 2 8 10 0 6 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG2122(Uncharacterized conserved protein) 13 7 7 7 1 4 1 4 1 0 2 1 2 20 4 5 4 2 3 2 0 3 5 2 5 5 4 2 4 1 2 1 3 0 2 2 1 6 0 6 3 1 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG29118() 1 0 3 0 0 0 1 2 0 0 0 0 0 0 0 3 2 0 0 0 5 2 18 2 3 23 6 5 10 7 9 11 4 4 14 1 0 0 0 4 2 4 0 0 0 0 0 0 0 0 0 2 0 0 0 4 COG3389(Uncharacterized protein conserved in archaea) 0 2 8 0 0 0 0 0 2 0 0 2 0 0 0 3 0 0 0 7 8 9 10 13 9 0 4 6 4 4 1 12 2 2 0 8 3 0 3 8 12 0 2 0 0 0 0 0 0 0 0 1 0 0 0 7 NOG26415() 0 7 3 22 4 0 3 5 1 2 0 0 3 0 0 1 1 4 0 1 2 2 4 0 3 0 1 2 2 0 2 8 8 3 12 14 0 2 6 9 6 5 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG19702() 19 4 8 5 2 1 1 1 4 0 3 2 2 10 2 4 0 0 3 1 4 3 5 1 2 0 3 2 1 0 2 2 6 2 10 7 3 15 2 3 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG09466() 6 6 3 7 1 0 1 4 0 0 0 0 3 1 2 2 5 1 2 5 4 0 3 2 3 9 0 3 3 0 2 6 5 0 12 3 7 19 4 9 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG1871(Chemotaxis protein; stimulates methylation of MCP proteins) 105 5 2 2 0 0 0 0 0 0 0 0 2 3 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG17948() 28 16 4 2 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 1 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 2 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3005(Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit) 124 0 3 0 0 0 0 0 0 0 0 0 0 5 0 0 0 3 0 0 0 0 2 0 0 0 2 0 0 0 1 0 0 0 1 0 7 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38169() 14 7 4 9 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 5 11 8 7 0 1 4 7 9 17 7 0 0 4 0 0 15 9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08770() 9 12 9 14 2 1 2 1 2 2 0 4 1 0 2 1 1 10 5 1 8 2 6 3 7 3 3 1 0 0 0 4 1 0 6 13 0 4 2 0 1 0 0 2 0 0 0 0 0 0 0 3 0 0 0 3 NOG39279() 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 5 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5496(Predicted thioesterase) 0 1 4 2 0 0 1 2 0 0 0 0 0 6 1 4 22 9 1 2 0 3 0 1 0 44 2 0 1 0 0 0 0 0 0 3 1 39 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG20607() 0 1 11 1 6 0 3 4 1 0 0 1 0 4 2 3 0 0 0 1 0 3 8 2 0 1 4 5 3 0 2 6 5 6 25 15 0 7 2 7 4 0 0 0 0 0 0 0 0 0 0 7 0 0 0 1 COG5321(Uncharacterized protein conserved in bacteria) 5 2 4 4 0 3 1 3 3 1 1 0 0 7 0 2 0 2 0 2 3 3 3 3 1 4 7 2 1 0 0 11 8 7 13 8 1 9 7 10 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG10738() 10 7 0 20 1 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 6 6 14 15 18 0 0 4 15 12 9 0 2 0 0 1 0 0 0 3 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3435(Gentisate 1,2-dioxygenase) 24 6 8 8 1 1 2 0 0 0 0 0 0 13 2 1 8 2 0 3 3 1 8 2 13 6 1 2 0 0 2 2 2 0 2 8 3 9 1 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3602(Uncharacterized protein conserved in bacteria) 31 16 12 5 1 3 2 2 1 2 4 2 0 6 6 2 0 0 1 2 0 2 3 2 0 0 3 5 1 0 1 0 0 5 2 15 4 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26664() 0 0 1 1 0 0 1 6 0 2 0 1 1 0 0 0 0 2 0 0 0 2 13 5 9 26 0 3 8 9 11 3 1 0 2 5 5 0 1 6 4 11 0 0 1 0 0 0 0 0 0 2 0 0 0 8 NOG12568() 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 0 17 38 3 0 3 0 1 0 0 50 0 1 0 0 0 0 0 1 0 1 0 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG39142() 9 8 0 8 4 1 3 0 0 0 0 0 0 0 0 0 0 0 0 2 12 6 11 9 10 0 1 5 2 8 8 0 2 2 6 0 0 19 10 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG24293() 4 17 29 11 0 3 2 2 1 2 0 1 0 0 2 2 2 0 6 8 5 2 4 0 6 3 0 1 1 0 1 3 1 6 6 12 0 1 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10583(Probable bifunctional chitinase/lysozyme) 141 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4138(ABC-type cobalamin transport system, ATPase component) 5 2 2 5 0 0 0 2 0 0 3 2 2 0 0 0 0 0 0 5 9 4 5 3 6 0 3 7 2 2 0 2 3 6 1 6 0 52 4 2 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13429() 42 11 4 1 1 0 0 4 6 2 5 1 2 5 6 4 2 0 4 2 4 2 2 0 0 0 0 2 0 0 1 1 4 0 7 3 2 17 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG5395(Predicted membrane protein) 1 1 2 6 0 1 2 1 2 0 8 5 2 10 0 2 6 0 3 7 5 6 4 2 2 0 6 6 0 0 2 5 5 2 3 2 1 19 4 3 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 12 NOG09902() 1 1 7 3 6 1 2 3 1 2 5 1 0 14 6 5 5 2 2 12 8 7 3 6 3 2 0 5 2 2 0 1 1 2 4 15 4 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16024() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 23 2 0 1 0 1 0 0 79 1 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1101(ABC-type uncharacterized transport system, ATPase component) 124 0 1 1 0 0 0 0 0 0 0 2 1 2 0 0 0 2 0 0 2 0 1 0 0 4 0 0 0 0 1 0 0 0 0 1 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3116(Cell division protein) 81 2 3 2 0 0 1 1 2 0 4 0 1 5 0 0 2 4 3 0 0 1 5 4 1 4 1 0 2 0 0 0 0 0 0 1 11 5 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG32583() 14 4 1 7 1 5 2 0 0 2 0 0 0 0 0 0 0 0 2 0 8 2 11 8 10 0 1 3 9 11 6 9 2 2 0 0 0 21 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19011() 7 10 13 5 1 0 3 3 1 0 1 2 3 5 2 1 0 2 1 1 8 5 1 7 2 1 2 2 2 1 3 4 1 4 8 13 6 6 3 3 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG19723(ATP synthase protein) 2 1 4 3 0 3 4 4 2 0 0 1 2 9 0 0 0 0 3 7 1 3 1 1 2 0 1 5 2 0 3 12 10 10 14 9 0 10 5 8 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG25061() 0 15 35 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 18 0 0 1 0 0 11 10 10 21 5 0 0 4 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19767(Resistance protein) 0 0 0 0 0 0 0 0 0 0 5 1 0 5 0 1 18 14 4 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 75 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3535(Uncharacterized conserved protein) 4 10 19 2 0 0 1 0 2 4 0 0 0 11 4 1 0 0 4 0 2 5 0 2 0 0 1 1 0 0 2 6 2 2 3 31 0 16 1 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 NOG06271(Glycosyl hydrolase) 47 1 2 1 0 0 0 2 1 1 0 0 5 4 0 1 1 0 0 3 0 4 1 3 2 8 4 4 0 0 2 3 14 6 2 6 6 3 1 3 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12901(Likely ribonuclease with RNase H fold) 6 7 0 10 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 3 10 6 10 0 3 3 5 17 8 3 1 2 0 2 0 15 15 3 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 COG4850(Uncharacterized conserved protein) 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 1 0 1 6 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG34885() 1 5 2 8 0 0 1 11 7 7 0 10 6 0 0 0 2 0 0 2 8 4 6 6 2 0 14 2 5 0 2 2 1 2 11 5 0 4 2 6 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG11923() 144 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3684(Tagatose-1,6-bisphosphate aldolase) 9 12 7 8 0 0 0 0 0 0 0 1 1 2 4 2 8 4 2 11 6 0 3 1 2 11 0 1 5 0 0 5 3 3 6 10 2 6 4 5 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG16565() 4 4 3 2 0 2 5 7 1 1 9 2 0 2 5 3 8 6 2 3 5 0 5 3 2 14 4 2 0 0 0 3 3 7 9 8 0 0 4 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG24088() 17 0 1 10 1 1 1 3 0 0 0 0 1 5 0 1 2 0 3 1 5 7 10 9 12 0 3 3 2 1 8 7 1 0 2 1 1 0 19 1 1 4 0 0 0 0 0 0 0 0 0 2 0 0 0 2 COG4692(Predicted neuraminidase (sialidase)) 11 0 12 1 2 2 1 2 0 0 1 0 0 1 0 3 12 6 4 0 0 2 1 1 3 5 0 0 3 1 0 2 5 6 4 7 0 23 15 7 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG22165() 1 2 22 6 3 0 0 2 0 0 0 0 0 0 4 1 0 0 2 1 1 7 4 8 0 0 8 12 5 0 0 4 3 2 2 19 0 9 5 5 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG4452(Inner membrane protein involved in colicin E2 resistance) 130 0 1 0 0 0 0 0 0 1 0 0 0 5 0 0 0 1 1 0 2 1 0 1 0 0 0 0 2 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06308() 105 1 1 0 1 0 0 0 0 0 1 4 0 9 10 3 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33433() 4 4 6 6 0 3 1 3 1 0 1 1 2 9 0 0 0 0 1 4 6 1 8 4 0 0 1 2 1 0 4 11 11 5 8 11 3 7 5 6 0 3 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG29905() 14 2 1 7 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 3 13 6 16 0 1 1 10 5 9 9 0 0 2 0 0 18 16 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 NOG21347() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 27 1 0 1 0 0 1 0 67 0 0 0 0 0 0 0 0 0 7 0 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07696() 3 4 12 3 3 0 1 2 2 2 2 2 0 5 2 2 0 0 13 1 0 8 2 1 4 0 3 0 0 0 0 3 1 0 2 19 1 42 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 COG1809(Uncharacterized conserved protein) 5 10 11 10 7 0 6 2 3 2 0 0 0 2 0 0 4 1 2 8 5 3 5 4 0 5 0 5 4 2 3 2 2 2 16 8 0 0 0 4 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 1 NOG06820() 0 3 5 1 0 1 1 0 0 0 0 0 0 2 4 1 0 0 0 2 8 4 14 7 3 0 9 0 0 2 0 15 8 6 4 6 0 0 8 11 4 3 0 0 0 0 0 0 0 0 0 3 0 0 0 12 NOG38677() 7 7 0 9 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 17 4 22 8 9 0 0 9 4 8 9 5 0 0 0 0 0 10 10 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1102(Cytidylate kinase) 0 5 19 8 0 1 0 0 0 0 0 0 1 6 3 1 0 2 0 5 3 5 7 1 2 4 7 2 2 0 3 8 8 4 0 12 5 5 0 4 6 0 1 0 0 0 0 0 0 0 0 2 0 0 0 5 COG1315(Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain) 83 14 13 2 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 4 13 1 0 2 1 1 2 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3420(Nitrous oxidase accessory protein) 54 0 4 3 0 0 1 4 0 0 0 0 0 3 5 2 5 0 0 0 6 0 7 1 1 3 1 2 0 4 6 1 1 4 0 4 10 9 0 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10630() 5 7 4 8 0 0 6 1 0 0 0 0 0 2 0 0 0 0 0 0 5 0 2 4 1 2 1 2 0 0 1 2 1 7 10 10 0 55 6 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG39233() 86 0 2 1 1 0 0 4 0 0 0 0 0 3 0 4 2 0 0 4 2 2 5 2 0 0 0 0 0 2 0 0 0 0 0 1 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16651() 17 2 0 0 1 0 0 0 0 0 2 0 0 10 0 2 6 9 1 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 3 0 28 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13024() 5 5 14 8 1 4 0 6 0 0 0 3 0 3 0 0 2 4 2 0 2 0 2 1 0 5 13 0 1 6 0 2 1 2 4 3 5 27 0 8 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG25387() 114 1 0 0 0 0 1 0 2 0 0 2 0 0 0 1 10 3 0 0 0 2 1 0 0 6 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3539(P pilus assembly protein, pilin FimA) 130 0 2 0 0 0 0 0 0 0 0 3 0 0 0 0 0 2 0 0 2 0 1 0 0 1 1 0 1 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4970(Tfp pilus assembly protein FimT) 94 1 3 0 2 0 0 0 0 0 3 1 0 9 2 1 0 1 3 0 0 1 0 0 0 3 0 0 0 0 0 0 0 0 0 0 9 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08874() 2 0 1 1 1 0 0 6 3 0 0 0 0 1 4 2 0 0 1 2 0 1 3 1 0 0 2 0 1 0 4 7 11 9 15 7 0 24 5 12 2 4 0 0 0 0 0 0 0 0 0 5 0 0 0 9 NOG17289() 53 1 2 0 0 1 0 0 0 2 1 5 0 6 0 1 0 0 1 0 1 0 2 1 1 0 3 0 0 0 0 0 0 0 0 3 1 60 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1955(Archaeal flagella assembly protein J) 0 2 17 2 0 0 0 0 0 0 0 4 0 1 0 0 0 0 0 1 6 6 5 4 3 0 2 8 2 3 0 11 20 12 2 5 1 0 1 4 8 8 0 0 0 0 0 0 0 0 0 1 0 0 0 7 COG2944(Predicted transcriptional regulator) 67 2 2 0 0 1 0 0 0 0 1 0 0 1 0 0 11 1 1 0 0 0 0 0 0 5 0 0 1 1 1 0 0 0 0 0 5 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12530(Integration host factor) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 24 0 2 1 1 0 1 0 47 1 2 1 0 0 0 0 0 0 3 0 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4791(Type III secretory pathway, component EscT) 33 0 6 0 0 0 0 4 0 0 0 0 0 0 0 4 14 18 3 6 0 0 3 0 6 0 3 0 0 0 0 0 2 0 0 31 2 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG25056() 0 2 0 2 0 2 1 5 1 3 4 1 2 2 4 0 1 2 0 6 4 2 4 3 5 17 4 6 4 24 0 6 7 5 1 1 0 3 5 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG29695() 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 3 4 4 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4717(Uncharacterized conserved protein) 72 0 1 3 0 0 0 0 0 0 0 0 0 3 4 0 0 0 0 0 5 0 0 0 0 1 0 0 0 0 3 2 0 0 2 1 0 44 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12777() 9 2 1 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 14 3 10 6 15 0 1 9 3 6 6 4 2 2 5 0 0 20 12 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 NOG12546() 1 0 0 0 0 0 0 0 0 0 0 1 0 2 4 0 11 15 2 0 1 0 3 1 0 62 2 1 0 0 0 0 0 0 0 6 0 30 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4520(Surface antigen) 6 6 3 2 0 1 0 2 0 3 0 2 0 4 0 2 1 4 0 1 0 0 2 0 1 1 3 5 2 0 2 7 9 6 10 9 6 35 3 3 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG0375(Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)) 47 0 0 3 2 1 0 0 0 0 0 0 0 2 0 0 0 0 4 0 6 2 4 4 1 0 1 0 2 3 3 0 0 0 0 0 0 58 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10747() 6 3 0 8 1 1 0 3 0 1 0 0 0 0 0 0 0 0 3 0 12 3 12 16 8 0 1 1 10 13 7 11 3 2 1 0 0 0 16 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG28089() 17 1 0 1 8 1 1 2 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 6 1 0 5 0 38 4 4 0 0 0 0 43 6 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG21693() 15 2 0 10 0 3 3 0 0 0 0 0 0 0 0 0 0 0 0 1 18 7 9 9 11 0 0 1 8 3 8 3 1 0 5 1 0 16 7 1 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 NOG12985() 8 3 1 11 2 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 11 2 16 6 13 0 0 4 7 15 6 6 0 0 3 0 0 7 12 0 0 0 0 0 0 0 0 0 0 0 0 2 0 3 0 1 NOG16384() 15 3 2 6 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 6 2 9 5 11 0 3 5 3 11 17 7 2 2 0 1 0 14 11 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 COG1740(Ni,Fe-hydrogenase I small subunit) 47 1 0 0 1 0 0 3 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 2 0 0 0 0 0 0 4 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1499(NMD protein affecting ribosome stability and mRNA decay) 0 2 9 6 1 3 0 0 0 0 0 4 2 3 0 1 0 0 2 4 4 10 5 1 0 0 2 5 8 4 6 7 7 3 0 8 0 1 2 6 5 6 0 0 0 0 0 0 0 0 0 2 0 0 0 16 COG3098(Uncharacterized protein conserved in bacteria) 30 6 2 1 0 0 0 2 1 3 7 0 2 1 0 1 0 0 0 0 0 0 1 0 0 0 2 0 1 0 3 1 2 0 0 0 6 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5607(Uncharacterized conserved protein) 9 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 2 2 1 2 2 0 0 1 0 0 0 0 0 0 0 2 115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1889(Fibrillarin-like rRNA methylase) 0 5 14 6 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 5 7 9 9 3 1 6 4 3 4 8 0 5 2 1 0 14 10 2 0 1 9 11 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG21802(ABC transporter permease) 5 21 50 23 0 0 0 2 0 0 0 0 0 2 0 0 0 2 0 4 1 0 5 0 0 1 2 4 3 0 0 0 0 2 5 4 2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG18385(Transposition protein) 140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14535() 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 10 20 2 0 0 0 0 1 0 62 2 0 0 0 0 0 0 0 0 4 0 40 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32268() 11 3 2 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 14 4 5 16 15 0 0 2 5 8 8 11 3 0 4 0 0 13 6 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 COG3308(Predicted membrane protein) 92 3 0 0 0 0 0 0 0 0 1 0 0 2 0 4 4 1 2 0 0 0 1 0 0 15 4 0 2 0 0 0 0 0 0 2 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24520(Integrase) 52 7 4 8 1 0 1 0 0 3 0 0 0 1 2 0 2 8 0 1 0 2 5 2 3 7 3 0 0 2 3 6 3 0 4 5 1 1 2 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11812() 5 11 2 5 4 1 3 4 3 1 0 0 1 10 3 1 0 0 0 3 3 0 3 1 0 0 6 3 2 0 2 10 1 0 15 11 0 14 5 3 1 2 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG27192() 2 9 26 6 0 0 4 4 0 0 0 0 0 0 11 3 2 6 5 2 5 2 8 4 6 5 0 2 6 0 3 0 1 0 6 7 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG29764() 0 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 5 11 0 0 0 0 0 0 22 0 0 0 0 0 3 1 0 0 0 0 96 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13627() 3 5 6 7 1 1 2 4 0 1 0 0 0 2 6 3 4 6 5 1 3 4 5 2 0 11 0 4 2 1 0 3 2 5 12 11 0 10 3 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1601(Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain) 1 4 18 6 0 2 0 0 0 0 0 1 0 4 5 1 3 2 1 7 1 1 12 3 2 9 6 3 3 6 0 0 2 1 0 13 10 1 0 6 6 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5210(GTPase-activating protein) 0 4 15 11 7 14 1 0 2 2 0 0 0 2 2 0 0 0 5 0 0 12 11 7 0 0 4 0 4 10 2 3 1 0 2 9 1 0 4 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG06152(Transcriptional regulator protein) 91 9 21 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 2 0 1 0 0 0 0 0 0 0 0 2 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1390(Archaeal/vacuolar-type H+-ATPase subunit E) 0 10 18 6 1 0 0 0 0 0 0 2 2 7 0 0 0 0 1 4 3 3 7 2 0 26 2 2 3 4 1 2 2 4 0 5 12 3 0 4 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG12611(Transcriptional protein) 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 17 2 3 0 0 0 0 0 52 0 0 0 0 0 0 0 0 0 5 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26190() 3 8 5 7 0 0 0 0 4 0 3 2 6 2 0 1 6 1 0 1 0 0 0 0 2 4 0 1 0 4 0 6 8 6 14 15 9 0 6 11 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22386() 1 0 16 3 4 0 2 5 4 2 6 0 0 3 0 1 0 0 0 1 2 7 4 5 3 0 2 6 3 1 6 4 4 2 13 2 4 2 4 16 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13644() 3 2 1 2 0 0 0 2 1 2 0 0 3 1 0 1 0 0 0 4 0 3 0 1 1 0 5 0 3 0 2 6 3 16 16 9 0 34 7 7 2 3 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG23888() 4 11 11 11 1 2 1 2 0 0 0 0 3 0 2 0 2 0 0 1 0 2 5 5 6 4 0 2 2 0 0 13 0 3 13 7 0 11 8 7 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18386(Macrolide 2-phosphotransferase) 0 0 0 0 0 0 0 0 0 0 0 1 0 4 0 1 5 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16918() 132 0 2 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12781() 9 7 1 12 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 1 15 3 9 6 10 0 3 3 4 3 12 6 3 2 0 0 0 19 10 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG10044() 3 3 4 5 0 2 0 3 2 2 6 2 0 10 2 1 0 0 3 8 2 0 2 1 0 0 4 4 1 1 1 6 3 2 9 17 3 20 1 5 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4681(Uncharacterized protein conserved in bacteria) 63 3 1 0 0 1 0 3 1 1 9 3 3 10 0 1 10 3 4 0 0 0 0 0 0 7 1 0 0 1 0 0 0 0 2 0 7 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1813(Predicted transcription factor, homolog of eukaryotic MBF1) 0 5 7 2 1 4 0 1 3 0 0 0 4 1 2 3 3 2 3 5 4 8 7 3 1 1 0 2 10 1 2 4 2 4 0 6 6 0 6 6 13 1 0 0 0 0 0 0 0 0 0 0 0 0 0 10 NOG18598() 52 4 2 4 2 4 2 3 2 2 3 4 2 5 2 2 2 0 4 1 3 0 4 4 2 0 1 4 2 0 1 0 0 2 4 2 0 1 3 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG14161(Acetyltransferase) 20 6 8 5 1 0 0 3 0 0 3 0 0 3 0 0 0 0 2 1 0 1 3 1 1 1 3 2 1 1 0 0 0 0 2 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16407() 7 1 0 6 1 3 0 0 0 0 0 0 1 0 0 0 0 0 0 3 15 4 8 8 13 0 0 7 4 17 6 4 1 1 0 0 0 17 11 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG25421() 0 2 5 3 15 0 4 4 1 5 3 0 0 9 2 3 0 2 3 2 1 4 1 0 1 4 4 0 2 0 6 1 2 4 14 7 0 9 3 7 5 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG4639(Predicted kinase) 92 0 0 0 1 1 0 0 0 0 2 0 0 0 0 0 4 2 0 0 2 0 0 0 0 2 2 0 1 2 2 1 0 2 0 0 0 12 12 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3875(Uncharacterized conserved protein) 2 4 15 5 0 1 0 0 0 2 0 0 0 6 1 2 2 0 0 12 10 12 15 5 3 4 2 1 11 0 1 0 2 2 0 3 5 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG31006() 18 0 0 0 0 1 0 1 0 0 0 0 0 4 0 0 0 0 0 2 2 0 1 0 0 2 0 0 1 0 1 0 0 0 3 0 0 103 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13015() 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 2 0 1 0 0 0 0 0 0 0 5 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06485(Peptidoglycan-Binding domain protein) 2 1 1 1 0 0 0 2 4 9 0 6 8 7 0 0 0 0 4 5 0 0 2 0 1 0 5 0 0 2 4 4 7 4 19 5 4 25 3 4 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19056() 142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14306() 0 2 15 4 0 0 0 2 2 0 0 0 0 6 1 0 0 0 2 4 3 1 1 1 0 0 0 0 0 0 1 0 1 3 2 2 6 78 1 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11695(Alpha/Beta hydrolase fold) 2 1 5 4 1 0 0 0 0 0 0 0 1 0 0 0 11 10 1 2 2 5 3 1 4 38 0 0 1 0 0 0 0 0 2 4 3 39 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38937() 12 3 0 9 0 3 2 0 0 0 0 0 2 0 0 0 0 0 0 0 9 10 10 7 9 0 1 5 8 6 7 7 0 2 5 0 0 13 10 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08856() 1 0 1 0 0 2 0 8 2 0 2 0 1 3 0 0 6 0 4 0 0 0 1 1 0 4 0 0 3 5 0 4 4 0 2 1 1 84 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG23324() 5 0 3 3 1 3 1 0 5 4 0 1 0 3 0 0 0 0 1 4 0 2 1 5 7 0 1 3 3 0 0 5 9 8 14 9 3 13 7 13 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16422() 8 1 1 12 1 3 0 0 0 2 0 0 2 0 0 0 0 0 1 0 8 4 17 11 5 1 2 1 6 7 2 2 1 2 4 2 0 20 13 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG16419() 9 5 0 13 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 1 11 2 15 9 9 1 4 8 7 9 12 7 1 2 0 0 0 0 9 3 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19121() 4 4 5 7 2 1 2 0 0 0 0 3 0 6 0 4 5 3 4 2 5 1 6 3 1 10 9 5 6 0 2 2 1 4 6 4 0 11 2 2 1 0 0 0 0 0 0 0 0 0 0 6 0 0 0 2 COG2184(Protein involved in cell division) 74 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 2 4 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 1 4 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04723() 93 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 2 1 0 0 0 0 0 0 0 0 2 2 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4115(Uncharacterized protein conserved in bacteria) 5 0 2 1 0 2 1 0 0 0 3 0 2 1 0 0 3 2 2 1 0 1 0 0 0 3 3 0 1 0 0 5 0 0 0 0 13 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG39237() 0 0 2 1 0 0 0 12 1 2 0 0 0 2 1 0 0 0 5 2 0 4 2 1 0 0 3 2 0 1 1 8 11 16 11 8 5 13 4 17 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG14249(Ectoine synthase) 47 1 0 0 0 0 0 0 0 2 0 0 2 1 0 2 0 0 1 0 0 1 2 0 0 0 1 0 1 0 0 2 0 0 0 0 0 74 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG16439() 14 0 0 15 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 3 9 7 12 7 15 0 0 6 6 6 5 7 1 0 2 0 0 12 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 COG3460(Uncharacterized enzyme of phenylacetate metabolism) 35 0 1 0 1 2 2 0 1 2 2 1 2 3 0 1 1 4 2 1 0 0 3 0 2 8 1 0 1 0 0 4 9 2 4 10 1 23 0 8 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08626() 3 10 8 5 0 1 0 12 0 0 6 0 1 0 4 3 0 4 23 0 0 0 0 1 0 1 7 0 2 5 0 5 6 0 1 2 0 26 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11296(Metal-Dependent hydrolase) 1 2 1 0 0 1 2 4 1 0 1 1 1 3 0 3 11 4 1 4 3 2 3 0 2 41 2 4 0 1 0 5 2 5 11 8 1 0 2 2 3 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 COG3183(Predicted restriction endonuclease) 62 3 7 4 0 0 0 0 1 0 0 5 2 0 2 0 2 3 1 1 1 0 1 1 0 8 3 1 1 1 4 1 2 0 6 3 1 11 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3623(Putative L-xylulose-5-phosphate 3-epimerase) 4 6 10 8 2 1 4 0 0 0 1 0 0 5 1 0 1 1 3 3 5 2 4 2 4 3 1 5 1 0 2 8 7 3 8 24 4 2 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG16403() 11 2 1 7 0 2 1 0 0 2 0 0 0 0 0 0 0 0 0 1 8 3 7 2 11 1 1 4 5 5 5 6 3 3 3 4 0 34 5 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 COG5662(Predicted transmembrane transcriptional regulator (anti-sigma factor)) 133 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 1 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09949() 137 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25505() 138 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10136(2Og-Fe(Ii) oxygenase) 3 13 10 3 4 0 0 2 0 4 1 0 0 2 0 0 2 0 0 4 4 0 4 2 6 5 9 5 0 11 2 2 4 1 4 6 0 1 22 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2218(Formylmethanofuran dehydrogenase subunit C) 5 10 5 6 1 0 0 0 0 0 0 0 1 2 2 2 0 0 1 7 0 3 4 3 5 0 6 8 2 0 2 0 12 7 4 18 4 10 1 7 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12883() 12 5 0 8 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 6 3 13 8 19 0 1 1 6 8 5 4 1 0 8 0 0 8 10 3 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 NOG10552() 7 4 2 4 1 1 0 4 0 0 0 0 0 0 0 2 5 1 0 3 0 3 3 3 4 4 0 5 1 2 0 2 0 2 11 9 4 36 2 6 2 4 0 2 0 0 0 0 0 0 0 1 0 0 0 0 NOG06264() 2 0 2 2 0 0 2 0 0 5 0 4 0 0 4 2 4 2 2 1 4 0 2 3 0 1 3 2 0 0 4 9 4 4 19 30 2 0 4 11 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1936(Predicted nucleotide kinase (related to CMP and AMP kinases)) 4 7 14 3 0 0 0 0 0 0 0 2 0 4 0 1 0 0 2 7 3 7 8 1 1 12 0 7 3 0 3 4 5 4 0 6 0 2 7 3 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 14 COG1303(Uncharacterized protein conserved in archaea) 1 5 12 6 0 0 0 0 0 0 0 0 0 4 0 1 0 0 1 4 9 8 6 7 3 7 5 4 3 3 1 5 5 2 0 8 4 1 4 3 8 0 0 0 0 0 0 0 0 1 0 2 0 0 0 7 NOG18027() 0 1 5 6 0 3 0 0 1 3 0 0 0 11 0 4 7 3 0 2 2 4 10 1 0 18 1 0 0 0 1 3 7 0 2 3 0 31 3 4 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1491(Predicted RNA-binding protein) 0 2 13 3 0 0 0 0 0 1 0 0 0 2 2 0 0 0 1 1 6 5 9 4 1 2 1 5 4 5 2 4 12 4 0 8 15 0 2 8 7 2 0 0 0 0 0 0 0 0 0 4 0 0 0 5 NOG13749() 0 0 0 0 0 0 0 1 0 0 1 3 0 1 0 0 18 17 0 0 0 0 0 0 0 22 1 0 0 0 0 0 0 0 4 4 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5491(Conserved protein implicated in secretion) 8 22 32 12 2 1 0 0 0 0 0 2 0 0 8 1 1 0 0 2 2 0 0 0 0 25 2 0 0 2 0 1 0 0 0 13 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35077() 17 3 2 14 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 15 7 8 6 4 0 1 3 7 9 4 3 1 0 0 0 0 18 7 1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG09965(Activator protein) 136 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2966(Uncharacterized conserved protein) 93 5 2 0 0 0 0 0 0 0 0 3 0 0 0 0 3 0 4 0 0 0 5 0 0 7 2 0 0 1 2 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3106(Predicted ATPase) 71 9 2 1 0 0 0 2 0 0 2 0 0 5 0 0 0 0 3 0 0 0 1 2 1 0 0 0 1 1 0 1 0 0 0 4 2 31 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08866() 4 2 1 0 0 2 1 0 2 8 0 0 2 5 0 2 0 0 6 8 1 0 0 0 2 0 1 2 0 0 0 6 8 9 26 9 2 5 5 14 1 3 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG4211(ABC-type glucose/galactose transport system, permease component) 15 4 3 9 0 0 1 0 0 0 0 0 0 0 2 0 0 10 0 1 4 8 8 10 6 4 3 1 1 0 2 0 2 3 11 7 2 14 3 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 COG1849(Uncharacterized protein conserved in archaea) 0 1 4 1 0 0 0 2 0 0 0 0 0 6 1 0 2 2 2 2 3 10 6 4 0 1 1 3 5 11 0 6 8 11 0 10 7 2 3 10 3 7 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG12536() 1 0 0 0 0 0 0 0 0 0 2 0 0 5 0 0 4 12 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13303() 91 0 3 1 0 0 2 0 1 0 1 0 0 3 0 1 6 5 0 2 0 0 0 0 2 2 2 0 0 0 0 0 0 0 0 0 14 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22763() 11 3 2 4 0 4 1 0 0 0 0 0 0 0 0 0 0 0 0 1 15 4 16 9 15 1 1 0 8 8 9 5 1 0 4 0 0 2 11 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG34834() 16 4 4 15 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 10 12 15 7 10 0 0 2 4 9 9 12 2 0 0 0 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG16449() 3 6 2 11 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 7 8 7 14 6 0 0 2 8 9 9 4 2 0 1 0 0 14 15 0 0 1 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG17740() 32 2 5 3 2 1 1 0 1 0 1 3 3 6 0 0 2 2 5 1 0 5 2 2 0 5 0 4 0 0 0 4 1 3 9 11 4 0 4 9 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3410(Uncharacterized conserved protein) 77 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 6 3 2 1 0 0 0 0 0 17 0 0 0 0 0 2 0 0 2 0 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04717(Magnesium-Protoporphyrin IX monomethyl ester protein) 9 2 0 10 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 3 9 10 6 0 6 3 6 7 18 0 0 0 0 0 0 32 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06894() 2 3 2 1 1 0 1 0 5 2 5 10 2 1 0 3 0 2 2 0 0 0 2 0 4 0 3 0 0 7 0 6 11 2 4 9 16 9 3 5 9 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG26547() 1 1 9 6 1 0 3 2 0 0 2 2 2 7 0 5 2 6 2 1 3 5 7 2 0 5 0 3 3 1 0 11 4 3 10 12 4 2 2 8 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1720(Uncharacterized conserved protein) 52 5 0 4 0 2 0 1 0 1 0 0 0 1 0 0 3 0 1 1 0 4 3 1 0 2 3 1 0 2 0 4 0 0 2 0 16 28 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18171(A domain family that is part of the cupin metalloenzyme superfamily) 12 2 8 3 4 3 2 4 4 4 15 4 0 6 2 3 2 5 3 1 0 2 0 1 0 2 9 0 3 3 0 6 3 0 4 0 2 2 3 5 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG4114(Uncharacterized Fe-S protein) 136 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12601() 8 6 5 5 0 6 2 7 1 5 3 0 2 7 4 1 5 0 3 0 0 0 4 0 0 8 1 0 2 0 3 3 2 0 8 10 1 14 4 1 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG16366() 22 2 2 5 1 4 0 0 0 1 0 0 0 0 0 0 0 0 0 0 12 1 9 11 7 0 0 0 2 6 11 6 1 5 2 1 0 20 6 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5430(Uncharacterized secreted protein) 101 1 1 0 0 0 0 0 2 3 2 4 5 2 0 0 0 0 1 0 0 0 1 0 0 8 0 0 1 0 1 0 0 0 2 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10748() 2 0 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 3 3 0 1 0 0 0 0 3 2 0 0 0 0 0 1 0 0 0 0 117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18387() 8 3 0 9 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 15 0 13 7 9 0 0 1 1 7 10 8 1 0 7 3 0 14 11 4 0 0 0 0 0 1 0 0 0 0 0 3 0 0 0 0 COG1483(Predicted ATPase (AAA+ superfamily)) 0 2 2 2 0 0 0 1 0 0 0 2 0 4 0 0 2 0 2 0 2 2 9 1 4 13 5 4 1 1 1 0 0 0 0 1 2 70 0 1 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG04007() 115 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3122(Uncharacterized protein conserved in bacteria) 31 6 2 0 2 0 0 0 0 2 0 0 0 1 0 0 0 0 4 0 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 1 7 78 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG36235() 128 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10635() 0 0 0 0 0 0 0 0 0 0 0 1 0 4 0 0 3 14 2 0 1 0 0 0 1 20 1 0 0 0 1 0 0 0 0 0 0 86 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG2238(Ribosomal protein S19E (S16A)) 2 12 17 1 2 0 0 0 0 1 0 1 0 5 6 0 0 0 0 3 3 6 10 3 2 3 1 6 2 1 2 4 1 1 2 17 10 0 1 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 7 COG3100(Uncharacterized protein conserved in bacteria) 18 4 0 2 1 0 0 7 0 0 3 2 1 1 0 0 0 1 6 0 0 0 0 0 0 0 1 0 1 0 0 1 0 0 4 0 11 70 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG07607(Fatty acid desaturase) 0 0 0 0 0 0 0 0 0 2 0 0 0 4 0 1 13 23 6 1 0 1 0 1 0 48 0 0 0 0 0 0 0 0 0 0 2 35 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33718() 9 3 0 9 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 11 4 25 5 11 24 0 2 7 12 5 1 3 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26942() 6 14 18 8 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 4 1 3 5 0 6 10 0 0 3 0 0 8 11 4 10 2 0 0 2 13 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3610(Uncharacterized conserved protein) 94 3 1 0 0 0 1 0 0 0 0 5 0 0 0 0 4 0 3 0 0 0 5 0 0 3 2 0 0 0 0 0 0 0 0 0 2 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17004() 135 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32600() 1 2 21 2 0 5 0 0 0 0 0 0 0 9 2 0 3 2 5 2 6 9 3 1 0 5 2 0 2 0 1 5 1 0 2 1 2 37 2 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2991(Uncharacterized protein conserved in bacteria) 14 4 7 0 2 0 1 0 2 1 2 0 2 4 4 1 0 0 1 6 0 1 4 1 2 0 0 0 1 0 0 0 0 2 0 2 14 55 0 2 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4106(Trans-aconitate methyltransferase) 70 4 5 4 1 1 0 0 0 0 0 0 0 4 0 0 1 0 0 0 5 3 3 3 0 1 3 2 2 6 1 1 0 0 2 1 0 2 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13366() 22 3 2 5 1 2 1 5 3 2 0 0 0 11 0 1 0 0 4 2 0 3 3 3 7 1 5 2 0 0 4 9 2 1 9 5 0 10 0 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG12980() 16 5 0 5 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 11 6 13 12 12 0 2 1 4 6 3 11 0 0 4 0 0 15 5 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG5419(Uncharacterized conserved protein) 136 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20627() 8 1 0 10 2 4 2 1 0 3 0 0 0 0 0 0 0 0 1 0 9 4 12 9 9 0 0 0 11 7 10 7 2 0 2 0 0 18 1 0 0 0 0 0 2 0 0 0 0 0 0 2 0 0 0 0 COG5660(Predicted integral membrane protein) 1 6 32 7 1 0 0 2 1 0 0 0 0 2 0 3 3 0 2 1 3 1 6 0 4 5 5 6 2 0 0 2 4 2 0 10 3 9 4 4 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG16541(ATP synthase protein) 11 4 0 13 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 13 5 6 7 17 0 0 2 5 6 5 4 1 4 5 2 0 0 20 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG12826() 8 8 0 12 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 6 15 13 9 0 3 2 14 4 14 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG33112() 7 4 0 13 2 4 1 0 0 0 0 0 0 0 0 0 0 0 0 1 14 3 14 7 4 0 1 3 6 10 7 3 2 1 0 0 0 18 10 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG11053() 0 0 4 0 0 0 0 1 4 0 0 2 2 10 2 0 0 2 1 2 0 0 0 1 1 5 0 3 0 1 1 5 1 8 6 9 0 49 3 6 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG33955() 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 2 0 0 2 2 0 2 2 2 0 5 2 6 104 2 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3584(Uncharacterized protein conserved in bacteria) 1 4 18 4 4 0 0 0 3 0 2 1 0 1 2 1 2 12 0 2 2 0 4 0 0 11 2 0 0 0 0 4 4 4 0 8 10 26 0 1 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG33042() 11 3 1 10 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 1 6 2 5 5 10 0 1 3 6 9 7 9 0 2 2 2 0 18 13 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG5023(Tubulin) 0 5 10 8 19 19 1 0 0 6 2 0 0 0 0 1 0 0 9 3 3 2 1 0 0 0 2 0 2 28 0 2 0 2 2 3 2 3 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13697() 134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16386() 7 1 2 12 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 10 2 12 7 7 1 0 2 6 2 6 4 1 2 2 0 0 24 18 0 1 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 NOG08879() 2 0 3 7 0 1 0 4 2 0 0 1 0 6 0 3 1 17 1 5 2 2 3 4 0 2 7 5 0 0 0 3 5 2 11 13 5 6 4 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11420() 135 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29450() 2 3 4 6 0 2 1 0 0 0 3 0 0 3 0 0 1 0 0 0 2 1 8 1 3 0 3 0 2 2 2 2 2 4 6 0 0 71 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20599() 8 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1 3 0 0 0 0 1 0 5 0 1 0 0 0 100 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38108() 10 4 0 12 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 15 4 8 9 13 1 1 3 9 6 15 1 2 2 2 0 0 0 10 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG39175() 13 1 1 9 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 19 3 10 11 2 0 1 11 3 6 6 3 2 4 0 1 0 16 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2139(Ribosomal protein L21E) 0 6 11 4 0 2 0 0 0 0 0 1 0 5 4 0 0 0 1 2 1 3 12 4 4 4 2 0 3 2 1 4 10 7 0 10 13 0 1 8 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG16005() 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 2 15 4 0 1 0 0 0 0 24 0 0 0 0 0 1 0 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13784() 10 1 5 2 5 0 1 2 0 0 2 3 3 1 2 2 1 4 0 5 3 6 9 1 3 0 1 0 0 0 0 4 8 4 12 21 6 0 2 0 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG06853() 6 8 8 9 0 0 1 0 0 0 0 0 0 9 1 5 0 0 2 3 3 4 4 4 6 2 10 5 0 0 0 3 7 2 6 7 6 3 1 2 0 2 0 0 0 0 0 2 0 0 0 1 0 0 0 4 NOG09312() 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 29 1 1 1 0 0 0 0 78 0 0 0 0 0 0 0 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5379(S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase) 3 0 3 1 2 0 0 0 1 0 0 0 0 2 0 0 2 3 1 2 0 0 0 0 0 6 0 0 0 0 2 0 0 0 0 2 6 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17927() 0 0 0 0 0 0 0 2 2 0 0 1 0 0 0 3 6 5 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 113 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2108(Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme) 0 3 8 2 0 0 0 0 0 0 0 0 0 6 0 0 4 0 1 10 10 8 7 4 2 0 3 2 1 3 0 7 13 3 0 2 3 0 7 6 11 8 0 0 0 0 0 0 0 0 0 0 2 0 0 0 NOG22303() 1 4 5 5 6 0 5 5 4 1 1 0 1 5 2 1 0 2 2 0 3 6 6 2 2 0 3 3 2 0 0 2 4 0 13 5 5 11 8 6 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG19836() 3 1 1 7 2 2 0 2 2 0 12 1 1 14 0 1 9 10 5 0 2 2 1 0 0 9 0 0 1 2 2 0 2 0 4 6 0 15 4 0 0 2 0 0 0 0 0 0 0 0 0 5 0 0 0 6 NOG28041() 0 2 3 2 1 5 0 0 8 0 0 2 4 3 3 5 14 6 5 3 6 0 9 2 3 15 3 6 0 0 0 1 0 1 0 14 0 2 0 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3731(Phosphotransferase system sorbitol-specific component IIA) 3 1 0 2 0 0 2 6 1 0 0 1 5 11 2 7 3 3 4 2 2 3 3 2 1 9 4 4 3 0 1 3 2 6 2 11 0 0 1 2 6 5 0 0 0 0 0 0 0 0 0 1 0 0 0 11 NOG11680(Dnaj molecular chaperone homology domain-containing protein) 135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG39444() 116 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 2 0 0 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4124(Beta-mannanase) 96 2 1 0 1 0 0 0 0 0 2 0 0 0 0 0 2 1 0 0 0 0 0 0 0 2 0 0 0 0 0 6 0 0 0 0 0 20 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5434(Endopolygalacturonase) 16 5 1 5 0 6 1 3 4 0 1 0 0 3 0 0 4 4 0 3 1 2 3 0 2 11 0 2 0 18 4 6 2 3 0 8 2 1 0 9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG19051() 8 8 3 13 0 1 9 2 0 3 1 0 2 0 2 0 0 0 1 3 2 2 8 3 1 0 5 5 0 0 2 1 3 3 16 1 4 7 2 7 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3198(Uncharacterized protein conserved in bacteria) 23 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 0 0 0 0 0 0 0 3 1 0 0 1 0 0 0 0 0 0 6 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13326() 8 9 5 7 0 1 0 0 0 0 0 0 0 0 2 0 0 1 0 3 1 4 8 10 3 6 1 1 7 2 2 5 2 2 11 16 5 0 4 1 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG38110() 4 1 3 2 0 6 0 0 0 0 1 0 2 3 2 2 6 4 8 1 2 6 1 0 3 11 4 1 1 2 0 3 0 2 4 7 2 36 1 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08013(Zipa, C-terminal domain (FtsZ-binding)) 85 1 0 1 0 0 0 0 1 0 0 1 0 2 3 2 9 5 4 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5185(Protein involved in chromosome segregation, interacts with SMC proteins) 2 5 61 11 6 3 0 0 0 0 0 0 0 0 0 9 0 0 0 0 1 5 2 1 1 0 0 0 2 4 0 1 2 2 2 3 0 5 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG4229(Predicted enolase-phosphatase) 46 2 1 3 2 0 1 3 0 0 0 3 0 0 0 0 0 0 0 0 2 0 1 1 0 1 2 0 1 1 0 4 1 0 0 2 2 38 15 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3655(Predicted transcriptional regulator) 86 1 0 0 0 0 1 0 0 1 0 2 0 3 2 2 0 0 3 0 2 1 0 0 1 1 0 0 0 0 0 2 2 0 2 1 3 11 1 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19126(UPF0090 protein) 0 0 0 0 7 0 4 1 5 1 1 1 4 2 0 1 1 4 2 0 2 0 2 0 0 4 1 3 1 2 0 9 8 9 19 11 2 6 3 12 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10776() 6 5 2 11 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 13 2 6 11 25 0 0 3 7 16 13 6 0 0 2 0 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2501(Uncharacterized conserved protein) 39 0 1 1 1 0 4 0 2 1 0 3 0 6 0 1 1 0 2 1 4 1 6 0 3 1 4 0 3 1 2 7 0 0 4 0 0 23 4 3 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG27562() 3 7 12 5 2 0 1 2 3 0 0 3 0 2 0 3 4 13 0 0 2 0 6 0 4 44 0 0 0 0 1 1 0 2 4 2 0 2 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38116() 4 6 1 10 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 8 1 10 9 17 0 0 4 5 10 17 5 1 2 0 2 0 6 5 1 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG27058() 132 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14598(Dna-Binding protein) 57 0 4 4 1 0 1 0 2 0 2 0 6 6 2 2 2 0 2 1 0 0 3 0 1 1 2 0 0 0 0 1 1 2 6 3 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG09477(Phycobilisome rod-core linker polypeptide) 21 1 0 0 5 2 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 1 3 0 0 5 2 0 6 0 17 2 2 0 0 0 24 35 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3851(Signal transduction histidine kinase, glucose-6-phosphate specific) 21 3 1 1 0 0 0 2 1 2 16 8 0 8 2 7 20 6 3 0 0 0 0 0 0 8 3 0 0 0 0 1 0 0 0 2 2 14 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1979(Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family) 55 5 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 1 1 0 1 0 0 0 3 2 0 0 0 0 1 20 39 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 NOG08449(Atp-Sensitive inward rectifier potassium protein) 105 0 1 1 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 1 1 0 0 4 0 0 0 0 0 0 1 12 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30387() 12 1 3 3 2 4 0 0 0 0 0 0 0 1 0 0 0 0 1 1 3 4 15 13 10 0 2 0 7 3 4 7 1 0 6 0 0 17 9 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG28545(Probable porin protein) 16 0 0 6 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 10 10 5 8 0 3 4 3 7 2 5 1 1 0 2 0 9 19 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 COG3213(Uncharacterized protein involved in response to NO) 89 3 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 2 5 7 4 1 1 2 0 0 0 1 1 0 0 0 0 5 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38136() 2 0 4 2 1 0 0 4 0 2 1 0 7 3 2 3 2 2 1 3 5 2 3 0 0 3 5 2 0 0 0 6 9 9 5 10 3 19 2 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG20630() 8 6 0 11 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 4 8 14 15 13 0 0 1 3 14 11 8 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG2348(Uncharacterized protein involved in methicillin resistance) 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 2 8 5 1 0 0 0 2 2 0 11 0 0 0 0 0 0 0 0 0 5 20 71 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG27574() 7 9 0 6 0 1 4 0 1 0 0 3 2 8 2 6 4 3 1 1 2 1 1 1 0 5 2 0 2 0 0 7 2 7 12 15 0 0 4 5 2 1 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG33431() 5 3 1 11 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 1 18 5 15 10 10 0 0 4 5 13 11 2 0 2 7 0 0 0 5 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2401(ABC-type ATPase fused to a predicted acetyltransferase domain) 74 0 3 0 1 0 0 2 1 3 2 2 2 0 0 1 3 9 2 1 0 2 1 2 0 7 0 0 0 0 0 4 0 0 0 4 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21686(Photosystem II reaction center J protein) 12 2 0 4 1 1 1 0 0 1 0 0 0 0 0 0 0 0 0 1 10 3 14 13 15 1 0 1 5 7 4 9 0 1 4 1 0 9 10 1 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 NOG21605() 0 8 0 0 17 3 0 0 0 0 0 0 0 11 57 0 0 0 0 0 3 0 0 0 1 0 0 8 0 0 0 0 0 2 0 2 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16540(Succinate dehydrogenase cytochrome) 10 7 11 7 1 2 3 1 1 0 0 0 1 2 4 2 0 0 0 4 5 4 8 1 7 3 1 3 6 2 2 0 0 1 4 7 4 4 10 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG10039() 4 3 0 1 0 3 1 1 1 0 1 2 5 0 2 0 0 0 2 4 3 4 4 3 0 0 1 0 0 0 1 7 5 6 22 15 0 10 2 9 0 2 0 0 0 0 0 2 0 0 0 2 0 0 0 5 NOG13273() 10 7 10 13 0 0 1 3 0 0 2 0 0 5 0 0 4 3 0 1 1 6 1 4 0 0 1 0 3 0 0 7 1 2 6 9 2 18 5 4 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG33304() 15 2 0 7 1 1 0 0 0 2 0 0 0 0 0 0 0 0 0 1 5 6 15 3 5 0 0 5 5 6 9 5 2 5 3 0 0 13 13 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 2 0 NOG16529(Protein involved in purine metabolism) 63 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 3 2 0 3 0 3 3 1 2 8 5 1 0 2 0 3 15 7 2 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG22840() 2 8 17 4 4 0 8 6 1 2 1 0 0 0 1 2 0 0 0 3 4 8 2 1 5 0 0 2 2 0 5 0 8 1 11 13 2 1 0 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4319(Ketosteroid isomerase homolog) 104 1 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 1 0 3 0 1 2 0 2 1 1 0 4 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG34694() 17 5 1 6 4 7 1 2 1 0 0 0 0 0 0 0 0 0 0 1 5 1 6 5 12 0 1 3 3 10 6 2 0 0 2 2 0 21 7 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3571(Predicted hydrolase of the alpha/beta-hydrolase fold) 29 1 8 2 0 1 0 0 0 0 0 1 0 5 0 1 1 6 1 1 0 2 5 2 0 22 0 2 1 2 0 5 1 2 0 17 2 5 5 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10808() 6 3 0 4 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 1 20 13 16 0 1 6 11 6 4 4 0 2 2 2 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12950() 90 1 1 2 0 0 0 0 4 1 0 0 3 0 2 2 2 0 3 0 0 4 4 0 0 3 0 0 0 3 0 2 0 2 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16389() 8 5 0 9 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 3 8 5 14 14 17 0 0 2 9 9 11 6 1 0 2 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG10140() 0 1 0 0 0 0 1 5 0 0 0 1 0 3 2 3 7 2 8 1 5 0 7 2 6 4 0 5 1 11 2 4 2 0 0 3 1 38 2 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13554() 5 1 1 0 1 1 0 0 0 0 2 0 0 7 0 1 4 0 2 1 0 3 2 3 0 0 2 4 2 0 0 2 8 10 11 3 7 30 0 6 10 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG32828() 12 3 1 9 2 2 0 0 0 0 0 0 0 2 0 0 0 0 0 2 9 7 14 3 10 2 1 5 6 9 11 9 0 0 2 0 0 5 3 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG18367() 7 5 4 6 1 0 1 3 3 1 1 2 0 1 0 0 2 0 1 6 1 0 5 1 2 0 3 7 2 0 2 4 4 4 16 8 4 1 5 5 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 10 NOG16436() 5 4 0 11 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 7 12 11 7 0 0 4 4 12 5 6 2 0 2 0 0 28 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3549(Plasmid maintenance system killer protein) 6 1 2 1 0 0 0 1 0 2 0 0 2 3 2 2 2 4 2 0 1 0 0 0 0 15 2 0 0 0 0 0 0 0 0 0 7 75 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12647() 0 0 0 0 0 0 0 1 0 2 1 0 0 0 0 0 0 1 3 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1510(Predicted transcriptional regulators) 45 7 1 2 3 1 1 5 1 1 0 2 4 4 2 0 0 1 2 0 0 3 0 0 0 1 3 0 1 1 0 1 1 0 4 3 6 21 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1437(Adenylate cyclase, class 2 (thermophilic)) 81 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 2 10 1 0 0 0 0 0 0 0 0 1 10 21 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11999(Transposition protein) 126 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4464(Capsular polysaccharide biosynthesis protein) 3 13 11 4 0 1 2 0 2 1 2 0 0 3 4 0 1 1 2 5 3 3 7 0 3 0 0 1 0 0 5 7 3 0 2 8 3 20 0 7 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG07842() 2 4 3 4 2 1 4 4 1 0 0 1 0 0 0 1 0 2 0 0 0 7 1 5 0 2 0 1 1 0 5 8 4 2 21 7 0 10 2 8 4 8 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG12659(Cdp-Alcohol phosphatidyltransferase) 2 1 3 7 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 5 0 109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12794(Photosystem II 11 protein) 5 4 0 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 2 24 13 17 0 4 2 5 12 6 9 0 0 5 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 COG3143(Chemotaxis protein) 98 11 0 0 0 1 0 0 0 0 0 1 0 0 0 0 1 0 1 0 0 0 0 0 1 0 1 0 1 1 4 0 0 0 0 0 4 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24511() 13 2 2 14 0 3 1 0 0 0 0 0 0 0 0 0 0 0 1 4 3 3 9 7 15 1 1 3 1 6 9 3 1 0 0 1 0 13 12 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23415(Methyltransferase, FkbM family) 5 5 5 9 0 0 2 1 1 0 0 0 0 2 2 2 0 2 1 2 0 8 1 1 2 17 0 4 2 2 5 5 3 6 5 10 2 4 6 4 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG12909() 41 1 1 2 2 1 0 2 0 0 1 1 0 11 0 4 3 1 3 0 3 0 0 0 0 0 5 0 1 5 0 1 2 3 0 3 0 23 9 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG06773() 33 5 0 0 0 0 0 0 0 0 1 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 5 0 2 0 0 0 0 0 0 0 2 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3326(Predicted membrane protein) 31 0 0 0 0 0 0 2 3 0 4 3 2 6 0 0 4 1 1 1 0 0 0 0 0 0 0 1 1 1 2 4 2 2 9 7 4 22 2 9 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5258(GTPase) 2 1 6 3 0 7 0 10 1 0 2 0 4 0 4 0 4 2 3 4 7 4 13 6 7 4 1 7 1 2 0 5 0 2 3 7 2 0 0 0 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4269(Predicted membrane protein) 10 2 8 4 1 1 2 0 1 2 3 0 2 8 2 4 2 0 10 2 3 6 2 2 3 1 1 2 3 0 0 3 1 3 6 5 2 20 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG22466() 0 3 11 5 1 0 0 0 1 0 3 1 4 2 0 0 0 0 1 2 0 7 2 1 7 1 2 6 1 0 5 5 0 5 4 8 8 14 3 11 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 3 COG4941(Predicted RNA polymerase sigma factor containing a TPR repeat domain) 112 0 1 0 2 0 0 0 0 1 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 2 0 0 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3838(Type IV secretory pathway, VirB2 components (pilins)) 121 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3824(Uncharacterized protein conserved in bacteria) 3 0 0 0 0 0 0 1 0 0 0 0 0 5 1 0 1 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 6 110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05982() 123 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22534() 1 9 2 5 0 2 0 9 6 0 1 3 0 2 0 1 4 10 4 0 0 3 3 4 2 6 1 0 1 0 0 2 1 1 8 10 1 19 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG32937() 0 0 0 2 0 4 2 4 6 2 3 0 2 3 2 6 4 6 0 1 0 0 3 0 2 13 6 4 1 0 0 3 2 6 4 15 2 10 5 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG3867(Arabinogalactan endo-1,4-beta-galactosidase) 0 5 10 1 10 1 1 2 2 0 0 1 3 4 0 0 0 3 0 1 2 1 1 2 2 2 2 2 4 2 0 7 2 2 20 6 3 2 1 13 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 8 COG1203(Predicted helicases) 29 2 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 2 4 6 5 3 0 0 3 7 2 1 2 11 41 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG17280() 2 5 8 1 0 2 3 3 1 1 4 2 1 6 4 0 1 0 3 2 0 2 4 4 8 1 4 1 3 0 1 9 3 2 25 5 1 1 0 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG24241() 0 0 1 1 0 0 0 0 1 2 2 0 2 5 2 0 1 0 6 8 1 1 2 0 2 5 0 2 2 0 0 8 1 3 5 0 0 52 4 4 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG31812() 13 2 0 10 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1 6 3 6 7 2 0 7 10 15 4 6 2 0 0 0 0 19 10 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG2074(2-phosphoglycerate kinase) 0 6 20 2 0 0 0 0 1 0 0 0 0 4 0 1 2 0 0 11 7 8 14 6 4 0 3 2 1 0 0 3 6 3 0 4 0 7 3 2 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG24508() 15 0 0 13 2 5 1 0 0 0 0 0 0 0 0 0 0 0 0 2 3 4 11 8 15 0 0 4 6 10 7 7 1 0 4 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 NOG14777(Uroporphyrinogen-Iii synthase) 2 0 1 1 0 1 0 0 0 3 3 0 2 9 0 0 0 2 5 0 0 2 2 1 0 0 3 4 2 0 2 4 6 3 19 17 2 12 0 11 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG09911() 7 3 4 8 1 3 0 0 0 0 7 0 4 3 0 0 11 7 1 0 2 3 4 2 7 4 9 1 3 2 5 5 6 6 0 5 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG19138() 1 4 4 1 1 1 7 0 4 0 0 1 0 4 0 0 1 2 1 2 4 0 3 3 4 0 1 4 2 0 2 8 4 2 25 4 0 4 4 7 3 5 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG3312(F0F1-type ATP synthase, subunit I) 28 3 2 1 0 0 0 1 1 0 6 1 0 3 0 0 1 0 0 1 2 0 4 0 1 0 0 0 0 1 0 1 0 0 2 6 12 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07966() 99 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09981() 106 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 7 3 0 0 0 0 0 0 0 5 4 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG16471(Transcriptional regulator protein) 108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 0 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 7 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09921() 10 9 7 7 0 0 1 3 0 0 0 0 0 1 2 2 1 0 0 1 0 6 2 6 4 4 7 2 2 0 1 3 3 4 5 14 9 0 5 4 2 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13364() 7 7 3 10 0 0 1 2 0 0 0 1 0 0 2 1 4 3 1 3 4 2 7 0 0 17 1 4 0 0 2 4 3 2 9 11 6 0 1 2 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG14472() 0 5 4 2 0 0 0 0 4 2 0 0 5 3 0 6 0 2 1 0 2 3 2 1 2 0 4 4 1 0 0 3 2 0 5 12 9 27 3 8 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG10035() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3361(Uncharacterized conserved protein) 2 1 1 0 1 3 0 2 0 2 0 0 0 5 2 2 2 7 2 5 4 4 10 4 1 7 3 3 3 2 1 6 8 2 2 3 0 7 3 8 4 5 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG38903() 112 1 0 1 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15844() 0 0 0 1 0 0 0 1 1 0 0 0 2 1 2 0 23 23 1 0 1 0 3 0 1 51 0 0 0 0 0 2 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14135() 4 2 2 3 1 2 0 0 1 2 4 0 3 4 2 0 2 0 3 0 0 1 1 0 0 3 3 2 2 1 0 5 4 7 12 2 0 33 2 11 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3551(Uncharacterized protein conserved in bacteria) 11 2 10 1 1 3 2 0 1 0 0 2 0 0 0 1 2 0 1 0 4 0 3 1 5 1 1 0 0 0 0 2 0 0 0 5 2 65 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4951(Uncharacterized protein conserved in bacteria) 27 1 1 1 0 0 0 2 2 0 0 0 0 4 0 2 2 2 1 0 2 2 2 0 1 8 3 0 0 2 2 0 6 2 0 5 5 40 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG22284() 123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23863() 32 6 2 3 0 0 1 2 3 4 1 2 0 6 0 6 0 1 5 2 0 0 0 1 0 0 4 1 1 0 0 3 2 5 8 9 1 8 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3518(Uncharacterized protein conserved in bacteria) 92 0 0 0 1 1 0 0 0 0 0 0 0 1 0 0 2 0 0 0 1 0 0 0 0 1 0 0 1 0 1 0 0 0 0 0 2 23 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11134() 52 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 2 2 0 1 2 0 3 4 2 1 1 7 2 1 4 0 0 32 0 2 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG08894(Succinylglutamate desuccinylase) 26 6 6 3 0 4 0 2 1 0 0 0 0 2 0 0 0 8 4 1 0 11 9 3 2 2 4 3 1 0 1 2 2 8 2 6 0 2 2 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22174() 6 15 11 2 0 2 4 0 1 0 2 0 3 1 0 0 1 0 1 5 5 4 6 1 2 4 0 1 3 0 0 3 4 4 4 11 8 6 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG1831(Predicted metal-dependent hydrolase (urease superfamily)) 0 2 5 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 6 10 12 7 5 1 0 7 6 1 2 1 9 6 4 0 13 0 0 3 7 2 2 0 0 0 0 0 0 0 0 0 4 0 0 0 10 NOG21260() 1 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 1 3 7 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG31161() 14 1 1 7 0 0 0 1 0 0 0 0 0 0 0 0 2 1 0 2 1 0 2 1 0 6 1 1 0 0 6 2 2 4 6 11 3 47 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG14763() 4 2 3 2 2 2 1 0 1 0 3 0 0 15 0 1 2 0 4 2 2 3 4 0 0 0 8 3 1 0 0 6 8 2 12 15 1 2 2 9 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3637(Opacity protein and related surface antigens) 3 1 4 0 0 0 0 6 0 7 4 4 3 4 0 2 2 0 1 0 0 0 1 1 0 5 0 0 0 1 0 1 0 0 13 5 2 47 2 4 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG28656() 1 6 5 3 2 1 1 5 0 0 0 1 2 0 2 2 0 6 4 1 0 0 3 1 5 4 0 2 2 2 0 9 6 4 16 6 3 7 1 9 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG18013() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 17 6 0 0 0 0 1 0 6 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16922(HNH endonuclease family) 0 2 2 8 2 0 3 3 0 0 5 0 1 0 0 2 10 9 13 0 0 0 0 0 2 19 0 0 0 0 0 0 0 0 0 3 7 24 0 0 5 0 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG21934() 123 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33099() 8 5 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 3 20 7 13 0 3 4 6 9 11 6 0 1 0 0 0 9 7 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2210(Uncharacterized conserved protein) 1 2 1 4 0 0 0 2 0 0 0 1 0 4 2 0 1 0 9 6 1 2 2 2 0 1 2 4 0 0 1 0 1 0 0 1 1 72 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG06281() 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 2 0 0 2 0 0 0 0 1 0 0 3 0 0 0 0 0 0 0 0 0 0 116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4776(Exoribonuclease II) 20 1 1 0 2 0 1 0 0 0 0 0 0 4 2 1 5 3 0 1 3 0 4 4 2 0 5 0 1 0 4 2 5 2 1 3 0 42 2 0 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4496(Uncharacterized protein conserved in bacteria) 7 7 9 5 1 0 2 5 2 2 0 4 4 5 2 2 3 1 2 2 0 0 2 1 4 2 2 3 4 0 4 3 2 0 3 4 5 11 1 3 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3486(Lysine/ornithine N-monooxygenase) 123 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4789(Type III secretory pathway, component EscV) 92 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 0 0 0 1 0 0 4 0 1 1 0 0 0 0 0 0 1 6 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16420() 11 2 1 7 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 14 3 6 7 10 0 0 2 5 11 9 2 0 1 0 0 0 19 7 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG0011(Uncharacterized conserved protein) 16 4 5 5 0 3 2 0 0 0 0 1 0 0 6 0 0 0 1 2 2 1 4 1 5 5 3 2 0 2 10 7 1 2 1 1 5 17 7 1 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG18988() 0 0 1 0 0 0 0 0 0 1 1 0 0 8 0 1 1 0 0 0 0 0 1 0 0 5 0 0 0 0 0 0 0 0 0 0 2 105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07779(Protein involved in c5-branched dibasic acid metabolism) 3 12 24 9 4 0 0 2 1 0 0 3 3 2 2 4 1 0 0 4 5 9 5 0 0 1 0 3 3 0 0 1 2 2 0 4 2 2 3 4 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12983() 68 0 1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 2 0 0 0 1 0 6 2 2 0 0 0 21 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4261(Predicted acyltransferase) 117 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25627() 119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5429(Uncharacterized secreted protein) 55 5 0 0 0 1 0 0 0 0 2 0 0 8 0 0 1 0 6 0 1 0 0 0 0 0 2 0 0 1 0 1 0 0 0 1 8 33 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12569() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 25 1 0 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22494() 57 2 2 0 0 2 1 2 1 0 0 1 0 11 0 2 2 5 2 0 2 1 4 0 0 1 2 2 1 2 2 0 1 4 2 5 2 3 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3701(Type IV secretory pathway, TrbF components) 113 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13346() 1 0 1 2 0 0 0 0 0 1 9 0 2 8 2 1 0 0 7 0 2 2 8 1 1 0 0 0 1 0 1 0 0 0 2 3 0 70 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3527(Alpha-acetolactate decarboxylase) 5 0 0 1 4 0 0 0 2 0 1 1 0 0 2 5 0 2 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 98 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5064(Karyopherin (importin) alpha) 0 4 10 9 12 20 1 4 0 0 0 0 0 0 0 0 0 0 5 0 4 3 4 0 0 0 0 0 2 42 0 0 0 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13253() 126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13950() 47 10 8 2 0 0 0 0 0 3 0 1 0 6 0 3 0 0 2 2 0 1 2 0 3 0 0 0 0 0 0 4 0 3 2 11 0 8 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2321(Predicted metalloprotease) 98 0 1 0 0 0 0 0 0 0 0 0 0 7 0 1 0 0 2 0 1 0 2 0 0 2 4 0 0 0 0 0 0 0 0 0 2 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16454(Inorganic carbon transport protein) 20 2 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 1 10 9 6 0 1 0 4 8 11 5 1 3 7 0 0 17 6 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14752() 3 2 2 0 0 2 1 1 3 3 0 0 5 4 2 1 0 1 1 2 2 0 5 0 0 0 2 0 2 0 1 12 4 4 25 8 2 11 7 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG04192(Protein involved in homophilic cell adhesion) 2 1 26 1 0 0 0 0 0 0 0 0 0 0 4 1 0 0 0 1 8 20 15 5 4 0 5 0 1 0 0 6 0 4 0 0 4 0 4 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG36582() 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 15 25 2 6 2 0 1 6 0 49 3 2 1 0 2 0 0 0 0 4 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08603() 82 2 0 2 0 0 0 0 0 0 2 1 0 2 0 3 0 0 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 4 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14729(Integrase) 24 6 10 8 0 1 0 0 0 0 0 0 0 2 0 0 0 2 1 0 6 10 14 1 7 0 5 0 3 2 2 2 1 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13517() 1 5 8 10 0 1 1 6 1 0 4 0 0 0 0 1 0 2 2 2 4 2 2 0 10 1 0 3 6 2 5 1 3 4 15 6 1 9 4 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3393(Predicted acetyltransferase) 38 0 0 0 1 1 0 0 0 0 2 0 0 0 0 0 2 2 0 2 0 0 1 0 0 8 0 0 0 0 0 0 0 0 0 0 2 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3137(Putative salt-induced outer membrane protein) 70 5 6 0 0 0 0 0 0 3 2 2 0 2 0 0 0 4 0 0 1 0 2 0 0 3 0 0 2 0 0 0 0 0 0 1 6 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16445() 5 4 2 6 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 6 2 13 9 9 0 0 4 5 8 11 9 0 0 0 0 0 0 19 4 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2125(Ribosomal protein S6E (S10)) 1 2 21 8 0 0 0 0 0 0 0 2 0 0 0 2 1 0 0 3 1 10 3 3 3 6 2 3 2 1 2 9 6 2 0 6 10 0 1 0 9 3 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3155(Uncharacterized protein involved in an early stage of isoprenoid biosynthesis) 33 11 29 4 1 3 2 0 0 4 0 0 0 1 0 0 0 0 0 0 0 2 2 1 2 1 0 1 2 3 0 0 2 0 1 6 5 6 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11350(Transcriptional activator protein) 121 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30114() 1 1 0 1 4 0 6 4 1 2 2 2 2 2 0 1 1 0 7 0 0 3 1 0 4 0 2 1 0 2 2 4 1 2 8 16 0 10 5 17 5 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG09634() 1 2 4 1 0 1 1 2 3 4 3 1 0 4 2 3 6 2 3 1 3 0 3 1 0 6 3 0 1 0 4 0 0 0 2 0 8 47 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG35897() 9 2 2 9 1 0 2 1 0 0 0 0 0 0 0 0 0 0 0 1 4 4 13 4 16 0 1 2 7 7 9 8 0 0 4 0 2 3 7 1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG26827() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21355() 11 4 2 7 3 2 1 1 0 0 0 0 1 0 0 0 0 0 0 3 11 4 13 5 10 0 3 1 3 3 11 8 5 2 5 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 COG3673(Uncharacterized conserved protein) 47 0 4 0 1 0 0 0 1 1 2 0 2 15 2 0 4 2 3 0 0 0 0 0 1 1 0 1 0 0 0 3 2 3 2 1 4 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17512(Bacterial SH3 domain homologues) 0 0 1 0 0 0 0 0 3 0 3 0 0 1 0 0 0 0 5 2 0 0 0 0 2 0 0 0 3 3 0 2 0 0 2 5 3 88 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25011() 109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 2 2 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1608(Predicted archaeal kinase) 0 2 13 7 0 1 0 0 1 0 0 0 2 0 0 0 1 0 0 1 9 10 8 5 0 6 0 2 0 2 1 2 3 2 0 3 3 6 0 10 2 9 0 0 0 0 0 0 0 0 0 2 0 0 0 11 COG5569(Uncharacterized conserved protein) 110 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20178() 2 0 2 1 0 0 1 0 3 1 1 2 1 9 0 1 2 2 3 2 0 0 3 2 1 0 2 2 3 1 2 7 14 0 10 8 4 11 1 6 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG22888(Protein involved in benzoate degradation via hydroxylation) 9 4 4 6 1 0 2 1 1 2 1 2 0 9 4 0 1 3 1 2 1 6 9 4 1 0 0 2 2 2 0 3 4 0 11 8 3 5 0 3 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08018() 1 2 0 0 0 0 0 0 0 0 0 0 0 2 4 2 1 0 0 2 5 9 8 0 3 0 5 1 1 2 9 6 8 6 0 5 5 2 6 7 6 6 0 0 0 0 0 0 0 0 0 1 0 0 0 9 COG1361(S-layer domain) 1 0 2 0 2 0 3 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 5 2 6 3 4 3 1 0 0 1 6 2 2 1 27 39 0 4 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG17528() 3 2 4 3 1 0 6 3 4 0 2 4 1 0 0 4 0 0 0 1 3 0 3 1 1 8 0 1 3 2 3 1 3 2 5 7 3 28 0 9 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19666() 6 3 0 1 0 3 1 7 0 1 3 0 0 8 0 1 2 0 1 0 0 0 3 1 1 2 3 2 1 0 1 8 6 5 12 9 1 14 6 3 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG2147(Ribosomal protein L19E) 0 4 11 12 0 0 0 0 0 0 0 4 0 0 7 1 2 1 1 1 0 4 8 1 3 5 5 0 0 2 3 1 3 2 2 10 5 0 2 13 4 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG5297(Cellobiohydrolase A (1,4-beta-cellobiosidase A)) 0 2 0 6 1 2 1 3 1 0 0 3 0 1 0 3 2 6 3 0 0 3 2 0 3 1 5 0 0 0 0 3 4 2 11 4 2 37 2 2 1 2 0 0 0 0 0 0 0 0 0 5 0 0 0 1 NOG09641() 3 3 2 4 0 4 1 8 0 1 1 1 4 4 0 1 2 2 4 0 1 4 3 7 7 1 5 2 6 2 2 1 3 1 10 3 3 0 2 3 3 2 0 0 0 0 0 0 0 0 0 2 0 0 0 6 COG2037(Formylmethanofuran:tetrahydromethanopterin formyltransferase) 9 9 5 8 0 2 0 1 0 2 0 1 4 0 2 4 0 1 0 4 2 7 4 2 3 0 3 0 3 0 0 0 6 3 6 17 1 11 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06069() 15 2 0 2 0 1 0 0 1 4 0 0 0 2 0 0 0 2 0 0 3 2 1 4 2 0 3 0 3 1 0 0 0 0 2 0 2 66 5 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09317() 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 9 14 2 1 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 52 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38481() 11 4 1 10 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 7 6 9 8 12 0 4 2 4 7 5 3 1 0 2 0 0 20 3 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG06750() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 4 0 0 0 0 0 0 0 1 0 0 0 0 1 1 2 0 0 3 108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4048(Uncharacterized protein conserved in archaea) 110 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06282() 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 4 112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11198() 122 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21350() 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 1 4 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11100() 2 2 3 4 3 0 3 4 0 1 0 0 0 5 2 2 0 2 3 0 3 5 6 1 10 1 2 2 3 0 0 1 2 6 2 17 1 16 4 2 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19483(Lipoprotein) 122 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11666() 5 6 12 9 0 3 2 2 1 3 0 1 0 0 0 0 3 0 1 0 2 3 2 1 6 3 2 0 4 0 0 3 2 2 10 7 2 10 3 4 0 2 0 0 0 0 0 0 0 0 0 5 0 0 0 2 COG1549(Queuine tRNA-ribosyltransferases, contain PUA domain) 0 1 4 2 0 0 0 0 0 0 0 1 0 2 0 2 0 0 0 4 11 13 13 8 2 0 2 0 1 2 5 5 10 3 0 4 0 0 4 6 5 4 0 0 0 0 0 0 0 0 0 1 0 0 0 8 COG3853(Uncharacterized protein involved in tellurite resistance) 57 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 2 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3283(Transcriptional regulator of aromatic amino acids metabolism) 52 4 1 2 0 2 2 0 1 0 7 4 0 1 0 1 0 0 1 0 1 0 1 2 1 7 0 0 3 0 2 3 1 2 2 5 2 11 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25683() 3 3 2 1 0 2 0 2 0 0 2 0 0 3 4 0 2 0 4 2 2 4 3 0 0 6 2 5 0 8 0 7 1 0 2 9 0 41 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3472(Uncharacterized conserved protein) 3 4 3 1 0 1 0 0 1 2 2 1 0 1 0 1 0 1 0 1 1 4 1 2 0 8 4 0 2 0 4 1 0 0 4 8 12 42 3 1 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG08941() 6 4 2 1 0 2 2 4 0 0 0 1 2 11 0 2 0 0 4 3 2 6 3 8 2 0 2 4 4 1 0 3 2 4 12 2 5 0 6 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG11424() 122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05015(Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) FT 1) 7 2 2 1 0 0 0 1 1 0 1 0 0 0 0 0 4 8 2 2 4 4 5 4 6 5 2 2 0 4 4 4 3 0 9 11 2 11 6 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG23662() 0 6 54 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 3 8 4 9 1 5 4 1 0 0 4 1 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2327(Uncharacterized conserved protein) 12 2 1 1 2 0 1 2 0 1 0 0 0 0 0 0 0 0 0 0 2 0 1 1 0 0 2 4 0 2 1 9 1 0 0 2 6 37 25 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG20749() 0 6 14 2 0 2 1 4 1 0 4 2 0 14 0 1 2 0 3 3 3 4 7 0 2 10 2 2 0 0 1 2 0 0 0 4 2 23 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG39163() 10 0 0 19 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 8 6 13 12 4 1 0 2 5 3 11 2 1 2 0 0 0 15 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG15890() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 25 0 0 0 0 0 0 0 50 2 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38266() 10 2 1 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 12 9 2 0 5 2 5 10 2 3 0 0 0 1 0 24 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG12271() 3 23 56 16 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27442(Elongator protein 3, MiaB family, Radical SAM) 3 0 7 6 0 1 6 2 0 0 0 6 2 8 11 7 2 0 2 3 3 1 1 4 5 0 0 11 11 0 5 2 0 2 0 7 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21738() 0 5 5 11 14 21 1 1 0 0 2 0 0 4 0 1 2 0 1 1 0 2 1 0 0 1 0 0 0 25 0 1 0 0 0 7 9 3 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG21016() 14 1 1 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 3 7 0 0 0 0 2 1 0 0 4 0 12 1 2 0 0 0 48 19 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11128() 116 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10338(Protein TraN) 111 1 3 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2442(Uncharacterized conserved protein) 0 0 2 1 0 0 0 0 0 0 0 0 0 3 2 0 2 2 0 0 1 0 1 0 0 6 0 0 1 0 0 0 0 0 0 0 1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2964(Uncharacterized protein conserved in bacteria) 107 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 2 0 1 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 5 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3869(Arginine kinase) 1 2 5 4 3 6 1 0 0 2 1 0 0 0 2 0 0 4 4 0 3 2 5 0 1 8 4 1 3 11 0 0 2 4 4 2 15 18 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35854() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 0 1 0 0 0 0 0 26 0 2 0 0 0 1 0 0 0 0 4 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13025() 8 5 0 11 0 1 0 1 0 0 0 0 1 1 0 1 0 0 0 0 14 2 15 8 8 2 1 4 4 7 13 6 1 0 0 4 0 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18235() 1 3 30 6 0 0 1 0 0 0 0 0 0 0 2 2 0 0 0 0 0 2 4 1 4 2 5 4 1 0 0 3 1 0 4 2 14 26 0 0 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11799() 1 2 0 1 0 1 1 7 1 2 7 1 0 4 0 3 0 0 2 3 1 2 1 1 3 0 5 3 0 0 3 6 6 8 2 6 3 11 9 4 1 2 0 0 0 0 0 0 0 0 0 6 0 0 0 3 NOG16413() 6 1 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 3 19 7 7 1 1 6 6 8 7 2 1 1 4 1 0 9 13 0 0 1 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG18380() 115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28920() 6 1 0 0 0 7 1 0 0 0 0 0 0 0 2 0 2 2 9 0 0 2 0 0 0 9 0 2 2 4 2 3 0 0 2 0 0 59 2 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG20011() 9 3 2 5 1 0 0 2 1 2 0 1 2 14 0 3 7 6 5 6 3 0 1 0 0 11 0 2 2 0 1 6 1 0 8 6 1 0 0 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 COG2932(Predicted transcriptional regulator) 39 1 3 0 0 0 1 0 0 0 0 0 0 1 0 1 1 0 0 0 0 5 3 1 0 2 6 2 1 0 4 1 0 2 2 5 0 36 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG08919(Protocatechuate protein) 4 1 4 2 1 4 2 3 0 0 7 0 6 6 2 2 4 4 2 4 2 0 6 3 0 2 6 4 3 0 0 3 6 6 10 3 4 0 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG11230() 1 2 11 1 1 1 1 1 3 0 0 1 0 0 2 3 2 2 2 4 0 2 0 2 1 0 5 3 1 0 2 7 6 4 21 3 3 2 6 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3058(Uncharacterized protein involved in formate dehydrogenase formation) 118 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15054(NAD/NADP octopine/nopaline dehydrogenase) 64 0 5 3 0 0 0 3 0 0 0 1 0 0 0 2 0 0 1 3 0 0 2 4 0 0 0 0 0 0 0 2 3 1 4 4 2 3 0 6 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG16640() 3 4 28 7 0 0 0 0 0 0 0 1 0 0 4 1 0 2 0 0 2 3 2 3 6 7 3 1 1 1 0 1 0 0 0 5 0 31 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19849() 72 1 2 2 2 0 1 0 0 2 0 1 0 0 4 0 0 0 0 0 1 1 0 1 0 0 5 2 0 1 0 1 5 0 0 5 1 9 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24555() 0 0 0 0 1 0 0 13 9 6 2 11 22 3 0 7 6 6 6 18 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 2 0 5 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35082() 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 0 3 0 0 6 1 0 0 0 1 0 0 0 0 0 2 103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1978(Uncharacterized protein conserved in bacteria) 0 2 0 3 1 0 2 0 7 0 0 0 0 6 0 3 9 5 1 2 3 0 2 3 2 28 6 0 0 0 2 2 3 2 7 2 2 6 2 2 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG2984(ABC-type uncharacterized transport system, periplasmic component) 67 3 0 0 1 0 0 0 0 0 8 0 0 3 0 0 2 2 0 0 0 0 0 1 0 4 0 0 0 1 4 1 1 0 0 2 6 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08865(Acyl-Carrier-Protein) 2 5 38 7 1 0 0 0 0 2 0 0 0 1 0 1 0 0 0 1 5 6 8 0 1 0 8 13 1 1 0 2 3 2 0 6 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG08812() 0 0 0 2 0 0 0 0 0 0 0 0 0 4 0 0 5 0 0 0 0 0 1 0 0 2 0 0 0 2 0 0 0 0 0 0 9 96 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11035() 0 5 4 0 0 0 0 5 0 0 3 0 0 0 0 0 0 2 1 2 0 3 3 3 6 0 2 0 0 1 2 3 0 0 0 0 0 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14023() 13 4 8 10 1 0 0 0 1 0 0 0 0 3 0 0 2 0 0 0 0 6 10 6 2 0 2 3 0 0 2 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG35234() 3 3 0 11 0 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 9 5 12 9 12 0 0 2 4 3 10 7 1 0 2 0 0 12 9 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1767(Triphosphoribosyl-dephospho-CoA synthetase) 35 4 6 8 0 1 0 1 0 0 0 0 0 3 0 0 0 4 2 4 0 1 7 3 2 0 1 2 1 0 2 1 5 4 2 12 0 9 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21646() 16 2 1 5 3 2 1 0 0 1 0 0 0 0 0 0 0 0 0 1 7 4 5 3 5 0 0 9 4 9 2 3 0 0 5 0 0 20 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08702(TPR repeat protein) 1 4 8 4 2 0 0 0 2 2 0 7 0 4 0 1 2 2 0 5 3 3 6 0 3 0 0 2 0 0 0 6 15 7 2 12 2 0 2 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09453() 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 6 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1355(Predicted dioxygenase) 1 3 8 10 1 2 0 2 0 0 0 1 0 2 2 3 2 2 0 1 7 0 8 2 3 14 1 0 1 0 0 1 0 0 0 0 25 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11775() 120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10867() 1 1 1 0 0 0 0 0 0 0 2 0 0 2 2 0 4 5 3 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 4 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3009(Uncharacterized protein conserved in bacteria) 100 0 1 0 0 1 0 0 1 0 0 2 0 0 6 1 0 0 1 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28525() 120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3167(Tfp pilus assembly protein PilO) 39 6 0 0 0 0 0 0 3 0 4 1 2 6 4 0 0 0 6 0 0 2 1 0 0 1 0 0 1 0 0 0 0 0 0 2 17 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13313() 39 1 4 1 3 0 0 3 1 5 0 1 0 3 2 2 1 0 6 0 0 4 2 2 0 0 1 0 1 1 2 2 0 0 3 1 1 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG18800() 2 1 1 1 0 1 0 1 1 4 1 1 4 6 0 0 4 3 4 2 0 0 4 2 7 2 3 2 2 0 2 2 4 2 10 1 17 16 0 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG34114() 7 3 1 6 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 11 4 10 0 1 8 6 5 8 7 1 3 6 0 0 14 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09475(Phycoerythrin protein) 20 2 1 2 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 0 0 0 0 3 2 0 0 0 25 2 2 0 0 0 0 39 3 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG20183() 1 0 1 3 1 0 1 0 0 3 1 0 0 4 2 1 0 0 3 7 0 2 3 0 6 2 0 3 2 0 0 7 1 6 6 8 0 27 5 6 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG16398() 7 3 2 2 1 1 2 0 0 0 0 0 2 0 0 0 0 0 0 0 10 8 14 6 14 0 0 2 7 7 7 9 1 0 2 1 0 0 7 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 1 NOG09443() 10 0 2 1 3 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 6 2 0 0 3 0 4 0 1 0 2 0 25 25 3 6 4 0 0 1 0 0 0 0 0 0 0 0 0 0 12 NOG11079() 72 6 3 0 0 0 1 2 2 0 0 0 2 2 2 0 0 0 0 3 0 0 4 0 2 0 0 0 0 0 0 0 0 2 4 2 0 6 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06493() 58 2 7 5 0 0 1 2 1 0 0 0 0 0 0 0 2 0 2 2 0 1 1 1 2 0 1 2 2 0 0 0 2 0 4 7 0 10 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 2 NOG20187() 3 5 6 4 1 2 0 2 5 0 1 1 0 6 0 1 0 0 0 1 1 2 2 1 1 1 4 0 1 0 0 7 5 4 16 9 1 11 4 6 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06397() 2 0 2 1 1 0 0 0 0 2 7 2 2 6 0 2 1 11 3 1 2 4 0 2 2 5 0 0 2 2 3 6 7 0 8 4 3 11 4 7 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5553(Predicted metal-dependent enzyme of the double-stranded beta helix superfamily) 56 3 1 3 0 0 0 4 0 0 0 2 0 3 5 0 7 0 5 3 0 1 2 0 0 0 0 0 1 0 2 3 1 2 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG22301() 16 2 0 7 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 6 2 16 12 10 0 0 3 7 12 7 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 NOG17757(Methyltransferase, FkbM) 1 5 2 5 0 0 1 4 0 0 0 0 0 0 2 0 1 1 0 0 0 0 2 0 0 0 0 0 1 1 2 4 2 0 2 1 1 79 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5648(Chromatin-associated proteins containing the HMG domain) 0 1 6 5 2 7 2 1 4 2 0 0 9 4 2 3 3 4 3 3 3 0 3 3 1 4 0 0 1 3 0 0 1 0 2 11 10 8 2 1 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG5402(Uncharacterized conserved protein) 19 7 2 3 0 0 7 6 1 0 0 0 0 2 0 0 0 0 0 1 7 0 8 4 10 6 0 5 4 0 0 3 1 0 6 7 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 6 0 0 0 2 NOG29622() 116 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16954(Type II secretory pathway, pseudopilin protein) 14 1 10 1 1 0 1 0 0 0 0 0 1 0 0 3 0 0 0 2 2 8 7 1 2 0 6 4 1 0 4 5 4 6 0 6 4 15 0 5 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14339() 3 13 8 7 1 1 0 0 1 2 0 0 0 4 4 1 1 0 2 11 0 2 0 1 1 0 2 1 3 0 0 10 4 4 12 3 1 0 4 5 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG25965() 0 2 4 3 0 1 3 8 1 0 6 0 8 1 0 0 0 2 14 2 0 2 5 6 4 3 3 2 0 2 1 7 11 0 0 2 0 11 0 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG3272(Uncharacterized conserved protein) 53 2 4 3 0 0 0 0 0 0 0 1 0 7 2 0 4 0 2 0 2 0 2 0 6 5 1 4 0 0 0 0 1 4 2 2 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14573() 3 0 1 2 0 0 2 3 0 2 2 0 2 0 0 0 6 6 1 2 0 0 4 0 0 28 0 1 1 3 0 1 1 0 2 9 2 28 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG05974() 117 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5565(Bacteriophage terminase large (ATPase) subunit and inactivated derivatives) 0 4 0 0 0 0 2 5 0 2 38 0 2 3 2 2 4 4 5 2 0 2 8 1 0 1 0 0 0 0 0 0 2 0 0 9 4 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10050() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 19 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG23604() 1 3 33 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 0 6 5 2 0 2 5 8 0 0 6 3 2 0 10 2 0 3 12 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG22771(Cyclic nucleotide-monophosphate binding domain-containing protein) 6 5 18 7 0 0 0 2 1 0 0 0 0 1 0 0 0 0 0 5 2 4 0 6 1 6 3 1 0 0 1 3 1 4 10 4 2 17 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5654(Uncharacterized conserved protein) 85 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4813(Trehalose utilization protein) 9 4 8 5 1 1 2 0 0 0 0 0 0 0 0 0 2 0 0 2 8 8 6 2 5 1 1 2 2 0 2 9 5 2 10 4 0 3 5 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG06518(UPF0089 protein Rv3740c) 0 2 1 0 0 0 0 0 0 0 2 6 0 4 0 0 4 7 4 0 0 0 3 0 0 31 0 0 0 0 4 0 0 0 0 0 2 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2156(K+-transporting ATPase, c chain) 108 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 0 1 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21518() 13 1 2 9 1 3 1 0 0 1 0 0 0 0 0 0 0 0 0 0 14 2 10 5 3 0 1 4 6 8 5 4 0 0 2 0 0 4 12 1 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG38122() 0 4 12 3 84 0 0 0 0 0 0 0 0 0 4 0 0 0 0 6 0 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07982() 83 1 1 2 0 2 0 0 0 0 0 0 0 0 2 0 1 0 2 0 0 0 0 1 0 0 0 0 0 0 0 1 1 0 2 16 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2129(Predicted phosphoesterases, related to the Icc protein) 0 0 0 2 0 4 0 0 0 2 0 1 0 0 0 2 6 4 5 0 0 0 0 0 0 60 0 0 1 1 0 0 0 0 0 2 24 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3534(Alpha-L-arabinofuranosidase) 6 6 1 8 1 3 5 0 3 0 0 0 1 1 4 3 0 5 1 3 0 0 7 1 1 0 0 0 0 3 0 3 4 6 2 17 7 2 7 2 1 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 COG1882(Pyruvate-formate lyase) 77 0 4 0 0 0 0 0 0 0 2 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 20 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11873(Transcriptional regulator protein) 4 0 0 0 1 0 0 1 0 0 5 0 0 5 0 0 0 1 1 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 96 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30381() 8 8 8 13 0 2 0 2 1 0 4 1 0 2 2 0 4 2 2 7 0 3 5 5 0 4 0 4 1 0 0 2 2 0 9 12 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG24745() 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 4 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4318(Uncharacterized protein conserved in bacteria) 65 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 1 5 0 0 0 0 0 30 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11819() 2 5 2 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 3 3 0 0 3 2 0 4 4 3 4 1 7 3 8 14 4 1 7 6 10 2 2 0 0 0 0 0 0 0 0 0 5 0 0 0 7 COG2011(ABC-type metal ion transport system, permease component) 86 1 1 1 0 0 0 0 1 3 0 3 2 2 0 0 0 2 0 0 0 0 2 1 0 4 0 0 0 0 2 1 0 0 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16492() 0 0 1 0 6 0 1 1 0 0 0 0 2 4 2 0 17 17 2 0 0 0 1 0 0 23 0 0 0 0 0 0 0 0 0 5 5 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08867() 1 2 0 3 0 0 1 3 0 2 5 0 0 17 0 1 0 0 9 0 0 2 2 0 2 0 0 1 0 1 0 7 2 3 12 3 0 27 4 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG14624() 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 4 9 0 1 5 2 2 0 4 28 0 1 0 0 0 0 4 0 0 21 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1144(Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit) 23 11 8 5 0 0 0 2 0 2 0 0 1 1 0 3 0 2 0 0 0 1 5 1 0 2 4 6 1 0 2 1 4 1 0 4 7 10 2 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG08705(Protein involved in nucleotide sugars metabolism) 3 0 4 0 0 0 2 7 0 2 1 0 0 6 0 1 2 0 5 0 5 3 5 1 0 0 4 4 1 0 1 3 3 2 4 7 3 26 3 6 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG06236() 3 5 2 2 1 0 0 2 2 1 4 0 0 0 0 2 4 0 1 2 0 0 5 0 5 25 0 0 2 1 0 1 1 2 4 2 0 36 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5490(Uncharacterized conserved protein) 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 15 2 0 0 0 0 0 0 16 0 0 0 0 2 0 0 0 0 0 0 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1909(Uncharacterized protein conserved in archaea) 0 4 13 3 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 2 1 4 4 5 1 8 7 9 4 4 3 6 7 0 0 6 7 0 0 1 5 2 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG32837() 9 2 0 7 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 10 2 11 6 10 0 0 3 1 8 8 9 0 0 3 0 0 17 4 0 0 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 COG5646(Uncharacterized conserved protein) 1 0 0 0 0 0 0 0 0 0 3 0 0 6 0 1 16 19 5 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5069(Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily)) 2 3 19 18 9 4 1 0 0 0 0 0 0 0 0 0 0 0 2 0 2 7 2 2 1 13 0 4 0 8 0 4 3 0 2 2 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08818() 1 1 2 3 5 0 1 5 1 0 6 0 2 0 1 1 3 3 1 0 2 1 4 0 0 1 1 1 0 1 1 6 7 1 12 12 2 2 2 13 2 4 0 0 0 0 0 0 0 0 0 4 0 0 0 1 COG2058(Ribosomal protein L12E/L44/L45/RPP1/RPP2) 0 2 13 2 0 3 0 0 0 0 0 0 0 5 2 1 0 0 0 7 0 7 10 4 2 5 3 0 1 4 3 6 2 0 0 14 7 0 1 2 3 1 0 0 0 0 0 0 0 0 0 1 0 0 0 5 NOG10839() 2 0 4 2 0 2 1 2 1 0 0 0 0 0 0 1 4 0 0 3 1 0 1 0 0 0 0 0 1 2 0 7 5 4 4 2 0 40 21 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4430(Uncharacterized protein conserved in bacteria) 47 0 0 0 0 0 0 0 0 0 2 0 0 1 2 0 1 5 3 0 0 0 1 1 0 1 0 0 3 2 0 0 0 0 0 2 10 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3595(Uncharacterized conserved protein) 74 9 2 2 0 0 0 0 0 0 1 0 2 2 0 0 3 0 2 0 0 0 2 2 3 5 0 0 1 2 0 1 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4679(Phage-related protein) 43 2 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 1 0 0 6 0 0 0 0 0 0 0 0 0 0 1 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22110() 59 2 2 1 0 0 0 0 0 1 0 1 2 1 0 0 0 0 3 0 1 0 3 1 0 0 0 0 0 0 1 7 1 0 8 3 0 8 1 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG05901(Complement component C9 protein) 0 2 0 0 28 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 2 26 0 0 1 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG1986(Uncharacterized conserved protein) 29 7 3 3 0 1 1 1 2 0 0 0 0 4 0 0 3 0 1 0 2 5 6 2 2 3 2 3 4 1 0 1 2 4 2 3 7 4 3 2 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG24031() 31 1 1 2 2 7 0 0 0 0 0 0 0 1 0 0 2 4 0 0 1 0 1 0 0 3 0 1 0 1 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3636(Predicted transcriptional regulator) 42 0 0 0 0 0 0 0 0 0 3 0 0 2 0 0 3 5 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 1 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3596(Predicted GTPase) 107 1 0 0 0 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 1 0 0 0 0 COG4632(Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase) 4 1 8 1 1 1 0 4 1 2 0 0 0 0 0 0 0 0 0 4 0 3 2 1 3 2 0 1 3 1 0 2 4 8 4 3 0 33 18 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13758() 0 0 0 0 0 0 0 4 0 1 3 0 0 1 0 0 13 14 2 0 1 0 0 0 0 40 0 0 0 0 0 1 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG34523() 115 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24107() 1 2 1 4 6 4 0 0 0 0 0 2 0 0 0 1 4 0 5 0 2 6 2 1 10 5 0 4 4 22 0 0 2 0 0 6 5 12 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG34702() 8 3 0 8 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 3 17 9 8 0 1 2 7 7 2 2 0 0 2 0 0 10 11 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1114(Branched-chain amino acid permeases) 84 0 0 0 1 0 0 0 0 0 4 0 0 5 2 0 2 2 2 1 0 0 1 0 0 2 0 0 0 0 0 1 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26630() 1 3 1 3 3 0 1 0 2 1 2 1 0 2 6 1 3 0 2 1 0 10 2 0 0 1 4 1 3 2 2 5 6 0 10 14 0 6 2 8 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3482(Uncharacterized conserved protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16292() 8 2 1 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 8 11 11 12 10 0 2 1 5 8 4 7 1 1 2 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG19167() 1 4 16 2 0 0 0 0 1 0 0 0 0 4 0 2 0 2 4 8 0 5 4 3 2 0 0 0 2 0 0 0 0 2 0 1 3 38 0 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG24498() 108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14379() 0 1 1 1 0 0 0 5 0 0 1 2 0 1 2 3 10 16 1 5 0 0 6 0 2 26 1 2 0 1 2 3 3 0 2 9 5 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10999(Proline rich signal peptide protein) 53 0 9 4 0 0 0 2 0 2 0 0 2 3 2 1 6 7 1 0 2 0 0 0 0 11 0 0 0 0 0 0 0 2 0 0 3 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3270(Uncharacterized conserved protein) 65 3 14 1 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 2 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 8 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5464(Uncharacterized conserved protein) 3 0 0 1 0 0 0 0 0 0 0 0 0 1 2 0 0 2 0 0 0 3 0 0 0 2 0 0 0 0 0 2 0 0 0 0 7 91 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4315(Uncharacterized protein conserved in bacteria) 65 2 2 4 0 0 0 2 2 0 0 0 0 6 0 1 2 0 1 0 0 2 1 1 0 1 2 1 1 0 0 0 0 4 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15945() 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 21 18 3 0 0 2 0 0 2 39 0 0 1 0 0 0 0 0 0 1 0 24 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11791() 3 6 6 4 0 2 1 2 1 0 0 2 2 0 0 1 6 3 3 2 2 1 4 1 0 0 1 5 1 0 2 2 10 1 6 5 0 16 3 2 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG10812() 9 3 0 12 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 10 14 7 8 0 1 2 8 9 4 5 0 0 4 0 0 1 2 1 0 3 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG33877() 2 2 8 3 1 3 1 15 0 2 4 0 1 0 2 5 0 0 13 1 0 3 1 2 0 0 3 1 2 0 0 2 3 2 2 1 4 19 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG08773() 112 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3698(Predicted periplasmic protein) 1 1 1 2 0 0 0 0 0 0 1 0 0 2 0 1 0 0 1 2 2 3 0 1 1 1 5 4 0 0 2 10 8 3 10 9 3 18 5 7 1 4 0 0 0 0 0 0 0 0 0 4 0 0 0 2 COG5350(Predicted protein tyrosine phosphatase) 8 12 7 7 0 0 2 0 0 2 0 0 0 0 0 0 2 0 0 0 2 3 4 4 5 0 3 4 0 0 2 4 1 6 16 8 0 1 5 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4132(ABC-type uncharacterized transport system, permease component) 64 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 2 0 1 0 2 5 0 0 0 0 2 0 0 0 0 2 0 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11726(Cdp-Alcohol phosphatidyltransferase) 46 4 2 3 0 0 0 0 1 0 0 0 0 6 0 1 3 0 0 1 0 1 0 0 0 7 1 1 0 0 0 6 5 3 5 5 2 0 3 5 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG31362() 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 13 28 2 0 0 0 1 0 0 24 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5489(Uncharacterized conserved protein) 109 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06421() 4 4 1 1 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 2 4 0 0 0 5 0 0 0 0 0 0 2 0 0 0 0 8 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5472(Predicted small integral membrane protein) 47 0 1 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2024(Phenylalanyl-tRNA synthetase alpha subunit (archaeal type)) 40 6 12 10 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 2 6 3 3 1 2 0 2 3 0 4 2 2 2 0 0 0 0 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG19120() 0 1 10 3 0 0 3 5 1 0 1 0 0 3 3 4 2 6 1 0 1 0 4 1 2 2 0 1 1 0 0 1 4 2 10 9 5 10 0 13 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07900(Heptosyltransferase) 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06229(Xylosidase) 4 2 2 0 9 3 7 0 1 6 2 1 4 0 2 0 1 3 0 1 2 1 3 5 4 2 7 4 1 4 7 2 2 5 5 5 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG16442(Photosystem II reaction center L protein) 8 3 6 8 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 4 16 13 16 1 0 3 6 5 5 0 0 0 3 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12544() 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 1 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 2 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4961(Flp pilus assembly protein TadG) 41 3 6 0 1 1 0 15 0 0 0 0 3 4 4 2 1 0 2 1 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 5 19 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3946(Type IV secretory pathway, VirJ component) 108 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12978() 13 1 2 2 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 3 3 2 4 2 0 0 3 1 6 4 2 2 1 0 4 1 0 44 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14462(Cell division protein FtsQ) 0 0 3 1 4 1 3 0 0 0 3 1 2 0 0 0 0 2 4 4 2 1 2 0 1 2 1 1 2 1 2 7 4 5 17 7 0 13 0 8 7 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG38754() 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 8 3 0 0 0 0 0 0 10 1 0 0 0 0 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21215(Endoribonuclease L-PSP) 4 1 1 4 0 0 1 1 1 2 0 1 2 8 0 4 9 6 2 0 1 0 2 1 1 0 0 1 2 0 0 3 2 2 13 11 2 13 0 8 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG20285(Copper resistance protein) 38 8 1 2 0 0 0 0 0 4 2 0 1 11 0 0 0 1 3 0 0 0 1 2 2 0 2 0 1 0 1 0 0 0 0 0 2 27 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG3633(Na+/serine symporter) 70 6 4 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 6 2 4 0 0 6 0 2 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04728() 10 0 0 1 1 1 0 4 1 2 0 0 3 0 0 0 0 0 0 1 2 0 1 1 0 0 0 2 0 1 0 6 4 0 0 0 0 40 29 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG15864() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 8 12 1 0 0 0 0 1 0 18 2 0 0 0 0 0 0 0 2 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23914() 1 4 8 1 0 1 2 0 0 3 1 1 0 1 0 2 2 2 0 4 5 2 4 3 4 0 3 11 1 0 6 3 4 0 13 9 0 0 1 3 3 3 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11719() 67 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 10 5 2 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 1 14 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1513(Cyanate lyase) 13 1 3 1 1 5 3 1 0 2 1 0 0 0 2 0 3 0 2 0 4 1 1 0 1 1 1 0 1 2 6 6 1 0 0 0 8 27 11 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG17497() 0 6 3 0 0 4 2 0 2 1 0 3 1 4 0 2 2 1 2 5 0 3 4 2 1 4 1 2 0 0 2 10 6 8 7 7 0 11 2 1 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG18074() 0 0 4 1 0 1 0 6 3 0 5 3 6 2 0 2 4 1 6 1 0 3 0 2 2 3 5 0 0 2 0 7 10 0 0 2 2 27 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14909(Replication protein) 103 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 1 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11215() 0 6 25 4 1 0 0 1 0 0 0 0 0 2 0 0 1 0 0 2 3 5 3 1 6 7 2 6 1 0 0 3 6 3 1 6 0 6 2 2 0 6 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11828(Acetyltransferase) 1 1 1 0 1 2 0 0 0 1 4 1 2 6 0 2 0 0 6 1 0 0 0 0 0 0 3 1 1 0 1 9 9 2 12 12 6 13 3 9 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 NOG06535(Transposase) 57 4 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 29 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19779() 2 1 1 10 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 8 7 16 6 10 0 0 1 10 12 10 5 1 0 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 0 0 COG3132(Uncharacterized protein conserved in bacteria) 83 0 1 0 0 1 0 0 0 0 0 0 0 0 1 2 0 0 2 0 0 0 0 1 0 0 1 0 0 0 1 2 0 0 0 0 2 9 2 0 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG36020() 0 0 0 0 1 0 0 6 0 2 5 3 0 9 0 2 4 0 4 0 0 4 2 0 0 5 10 3 1 0 0 0 1 0 0 3 4 40 1 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG1242(Predicted Fe-S oxidoreductase) 42 3 8 5 0 1 0 0 3 0 0 3 2 2 0 0 0 0 3 1 1 2 5 0 2 0 4 1 1 0 0 0 1 0 0 3 6 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06401(Peptidase) 0 0 4 1 7 0 1 1 9 0 1 6 0 0 2 2 0 0 1 0 0 2 2 0 0 5 0 0 0 5 0 7 2 4 8 11 2 16 3 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08011(2,3-Dihydroxyphenylpropionate 1,2 protein) 94 1 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2865(Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen) 4 6 0 0 2 3 1 3 0 3 0 0 0 7 0 1 4 0 1 1 0 0 0 1 2 1 0 0 0 6 0 0 0 0 0 2 15 49 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3228(Uncharacterized protein conserved in bacteria) 73 1 0 2 0 0 0 0 0 0 0 0 0 3 2 1 1 0 2 0 0 2 2 0 0 1 4 0 0 0 0 0 0 0 0 0 4 11 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1992(Uncharacterized conserved protein) 5 5 11 3 0 0 0 2 0 0 0 6 0 3 7 2 0 0 0 0 0 3 3 2 0 11 1 0 3 1 1 3 7 6 0 8 0 0 2 7 2 2 0 1 0 0 0 0 0 0 0 3 0 0 0 3 NOG16017() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 13 1 2 0 1 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12944() 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 13 15 1 0 0 0 0 0 0 44 1 0 0 0 0 0 0 1 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14728() 4 0 1 3 1 1 1 1 0 5 2 1 1 10 0 0 2 0 5 3 0 2 4 1 0 0 1 3 0 0 0 7 3 9 6 7 0 10 3 6 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG08798() 26 0 0 0 3 0 1 0 0 0 0 0 0 1 0 0 0 2 0 4 2 3 1 2 0 6 4 1 3 0 0 3 6 2 16 11 1 0 2 6 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG21465() 22 1 1 5 0 5 3 0 0 1 0 0 0 0 0 0 0 0 0 0 11 2 12 8 7 1 1 2 4 10 7 1 0 0 4 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG11822() 1 1 2 1 2 2 2 9 2 1 2 0 2 3 1 3 4 4 4 6 2 0 1 1 0 1 3 0 0 0 0 0 1 0 4 7 2 32 5 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2929(Uncharacterized protein conserved in bacteria) 5 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 2 5 1 2 0 0 0 0 0 5 0 1 1 0 0 0 0 0 2 0 11 72 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15916() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4302(Ethanolamine ammonia-lyase, small subunit) 102 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06225() 99 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21634() 1 2 5 4 0 0 0 2 0 0 0 0 0 2 0 0 0 2 0 1 3 0 6 2 1 0 5 5 3 1 0 5 1 5 18 13 1 2 3 7 6 4 0 0 0 0 0 0 1 0 0 0 0 0 0 1 COG3402(Uncharacterized conserved protein) 1 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 4 99 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG21383(Inhibitor protein) 0 3 10 5 5 1 0 6 0 0 0 1 0 2 2 2 2 0 1 4 6 5 10 3 3 0 0 4 0 11 0 2 1 0 6 4 3 9 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG18166() 0 1 4 2 0 3 0 2 0 2 0 0 0 3 0 0 2 5 1 2 2 2 0 2 0 6 0 0 0 0 0 0 0 0 0 3 33 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17878() 0 0 1 0 0 1 0 0 1 0 1 0 0 3 0 0 2 2 0 0 1 1 0 0 2 2 1 0 0 3 0 0 0 0 2 1 0 78 0 5 1 0 0 0 0 0 1 0 0 0 2 0 0 0 0 1 COG3676(Transposase and inactivated derivatives) 1 4 0 0 3 2 0 0 0 0 0 0 3 18 0 1 3 0 3 0 3 0 0 3 0 7 0 0 0 0 0 1 0 0 0 2 18 38 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08921(Protein involved in glycerolipid metabolism) 0 0 1 1 0 0 0 0 1 0 2 0 0 2 0 0 14 15 0 0 2 0 0 1 2 59 0 0 0 1 0 1 0 0 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4199(Uncharacterized protein conserved in bacteria) 6 1 0 2 0 1 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 1 1 1 1 2 0 0 0 8 0 0 0 3 2 57 18 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16680() 105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG27599() 1 1 2 7 1 0 1 0 2 0 0 0 2 4 0 1 5 8 1 5 1 2 9 3 1 1 0 3 1 1 1 9 3 3 8 12 0 2 1 6 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG10143(Transposition protein) 106 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38492() 0 3 2 1 1 0 1 0 1 3 0 0 0 0 0 0 0 0 0 0 4 0 2 0 5 0 1 4 0 0 1 12 5 2 38 7 0 0 2 5 3 1 0 0 0 1 0 0 0 0 0 4 0 0 0 3 COG0676(Uncharacterized enzymes related to aldose 1-epimerase) 29 7 5 0 0 0 0 0 0 5 0 0 0 4 2 4 7 8 5 0 0 0 1 0 0 7 0 0 1 1 0 0 0 2 0 0 14 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1416(Uncharacterized conserved protein) 3 0 0 0 0 0 0 0 0 0 1 1 2 5 0 0 7 0 3 1 0 0 0 0 1 3 1 0 1 1 0 0 0 0 0 1 6 72 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13285() 9 9 13 8 1 1 0 3 1 0 2 0 0 11 4 2 1 0 3 2 2 3 10 4 1 0 10 0 2 1 3 1 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG38766() 110 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4705(Uncharacterized membrane-anchored protein conserved in bacteria) 104 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1817(Uncharacterized protein conserved in archaea) 2 8 25 3 0 0 0 0 1 0 0 0 0 7 0 0 0 0 0 4 2 4 4 1 1 20 0 0 2 0 1 0 0 0 2 4 4 10 0 2 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG12596(Dna-Binding protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 28 0 0 0 0 0 0 0 26 1 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4267(Predicted membrane protein) 90 0 0 0 0 0 0 0 0 0 0 3 0 4 3 0 0 0 0 2 0 0 0 0 0 5 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3821(Predicted membrane protein) 46 0 0 0 0 1 2 2 0 5 5 1 0 8 3 1 3 1 1 0 0 0 1 0 1 2 1 0 1 0 0 1 0 0 0 4 8 12 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13488() 105 1 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1444(Predicted P-loop ATPase fused to an acetyltransferase) 21 11 5 3 7 1 0 0 0 1 2 2 2 0 0 0 0 0 0 0 0 5 1 0 0 0 0 0 0 5 2 0 0 0 2 0 16 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05991() 80 4 5 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 1 0 1 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15926() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 8 2 2 4 2 5 1 0 12 2 0 2 0 1 0 1 0 0 11 0 53 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22567() 2 0 3 3 0 2 1 0 0 0 0 0 0 0 2 0 0 2 2 0 4 5 19 5 6 3 2 3 5 0 0 3 9 2 6 3 2 9 0 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1618(Predicted nucleotide kinase) 0 1 5 0 0 0 0 0 0 0 0 1 0 6 0 1 1 0 0 6 1 12 8 5 5 0 4 2 7 1 3 4 10 2 2 3 2 0 1 8 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG09871(Metal-Dependent phosphohydrolase) 111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16379(CAB/ELIP/HLIP protein) 15 0 1 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 2 4 2 6 0 0 0 4 9 4 6 3 2 2 2 0 20 13 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1717(Ribosomal protein L32E) 0 4 7 6 0 0 0 0 0 0 0 1 0 0 8 2 2 0 0 0 2 5 4 4 3 4 2 1 3 2 2 4 2 1 0 5 13 4 0 7 4 4 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG2320(Uncharacterized conserved protein) 18 1 9 4 0 0 1 2 0 0 7 1 0 1 0 0 4 6 2 4 3 0 4 1 0 7 3 3 0 1 1 0 1 2 0 7 11 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10866() 3 0 0 1 0 0 0 1 1 0 0 0 2 6 0 2 0 0 7 0 1 2 0 0 0 0 0 0 1 0 0 0 0 0 0 2 4 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG09958(Site specific recombinase, phage integrase) 48 2 2 2 0 0 1 4 1 1 0 0 0 6 2 2 3 0 2 0 0 0 6 3 2 0 1 0 0 3 0 0 0 0 8 3 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG27797(Glycan acetyltransferase) 0 2 15 2 0 0 0 0 0 0 0 0 0 4 0 1 0 0 0 4 3 12 16 1 1 5 5 3 2 1 4 0 6 3 0 3 2 0 0 4 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG09952() 0 0 1 1 2 0 1 5 1 0 7 6 0 4 2 2 5 4 3 0 1 6 2 3 3 2 1 2 0 1 2 8 2 0 4 6 0 7 1 12 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG08454() 4 5 2 6 0 0 2 4 0 0 0 0 0 0 0 0 4 0 3 3 4 0 4 2 2 6 2 2 2 0 0 2 0 0 6 7 6 20 3 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG06075() 10 1 7 2 3 1 0 0 0 0 0 0 2 0 0 0 0 2 2 2 2 2 0 1 0 2 1 0 1 0 0 2 2 0 2 0 3 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10043() 3 0 1 2 0 1 1 0 0 0 1 0 1 7 4 0 0 0 0 1 2 0 1 0 0 0 3 0 1 0 6 2 5 5 14 12 1 16 9 5 5 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG15984(Sec-Independent protein translocase protein tatB) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 12 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG3671(Predicted membrane protein) 48 7 5 1 0 1 0 4 0 0 2 1 0 0 3 0 1 0 0 0 0 0 0 0 0 10 0 0 2 0 0 1 0 2 2 8 2 5 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3720(Putative heme degradation protein) 58 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 1 0 1 1 0 2 1 1 0 0 1 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4185(Uncharacterized protein conserved in bacteria) 40 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 4 1 0 0 0 0 0 0 0 0 0 4 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18234() 2 1 15 1 2 1 0 0 0 1 0 0 2 3 0 1 0 0 3 0 2 4 4 2 0 1 0 2 3 1 0 4 5 8 4 9 2 5 2 10 1 4 0 0 2 0 0 0 0 0 0 0 0 0 0 3 COG4422(Bacteriophage protein gp37) 65 0 0 1 0 0 0 0 0 0 0 0 0 4 0 1 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 6 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09706() 1 3 4 3 5 0 2 0 6 0 0 4 1 0 0 1 0 0 1 0 3 3 6 4 2 0 0 2 1 2 2 4 4 2 24 8 2 1 0 6 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG29377() 4 4 5 5 0 0 1 1 2 0 0 0 0 3 0 1 0 1 2 2 1 0 4 7 0 0 1 3 3 0 2 11 4 13 13 3 2 0 2 6 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG17969() 25 1 0 0 0 0 0 0 0 0 0 0 0 6 0 1 0 0 0 0 0 2 0 1 2 1 3 3 0 0 0 1 1 2 0 0 6 52 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG30821() 2 3 5 1 1 0 5 2 1 1 0 0 2 4 0 1 0 0 0 3 4 2 3 3 0 0 4 1 1 1 1 5 3 1 19 10 0 0 2 4 2 6 0 0 0 0 0 0 0 0 0 3 0 0 0 4 NOG23642(Tetratricopeptide repeats) 1 0 4 0 1 0 4 6 2 0 7 2 0 3 1 1 2 4 0 3 0 0 2 0 0 1 2 0 3 0 2 5 4 4 4 6 2 18 0 15 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08843(Sodium/Hydrogen exchanger protein) 88 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 6 0 1 2 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG36115() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 5 4 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 97 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23652() 107 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0699(Predicted GTPases (dynamin-related)) 4 4 15 4 8 10 1 0 0 1 0 0 3 0 2 0 3 2 1 0 3 1 6 0 0 2 0 6 0 9 0 2 0 0 4 2 4 10 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4220(Phage DNA packaging protein, Nu1 subunit of terminase) 0 0 1 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06546() 107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5053(Translation initiation factor 4E (eIF-4E)) 3 2 1 5 0 1 0 3 4 0 1 0 1 4 4 3 9 6 3 4 5 2 2 3 1 4 3 1 0 3 5 1 0 6 4 11 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10308() 80 4 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 2 0 0 4 0 0 0 0 0 0 0 0 0 4 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10015(Protein involved in serine-isocitrate lyase pathway) 1 6 6 7 2 0 1 6 0 0 0 0 0 3 1 1 0 1 0 1 2 3 5 6 2 0 3 3 3 1 4 1 1 0 4 12 3 15 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG26763() 0 3 12 4 0 0 0 2 0 0 2 0 3 3 0 1 8 1 1 8 2 6 6 0 1 9 0 2 0 0 2 1 0 0 2 3 3 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21019() 1 5 2 0 4 0 0 0 0 0 0 0 0 30 42 0 0 0 0 0 0 2 2 11 0 0 3 0 0 0 0 0 0 2 0 1 1 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2160(L-arabinose isomerase) 30 0 0 0 1 0 3 1 0 0 0 2 1 0 2 0 8 18 2 0 0 1 2 0 0 8 0 0 1 0 0 3 0 0 10 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5207(Isopeptidase T) 0 1 13 5 4 8 0 4 0 3 3 0 5 4 0 0 3 3 4 14 1 1 1 1 0 11 0 0 0 9 0 0 0 0 0 6 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3129(Predicted SAM-dependent methyltransferase) 57 7 5 0 1 0 0 4 7 0 3 4 4 1 0 0 0 0 4 0 0 0 1 0 0 0 1 0 0 4 1 0 0 0 0 0 0 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17316() 7 0 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 5 0 2 0 0 4 66 16 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1436(Archaeal/vacuolar-type H+-ATPase subunit F) 0 3 16 1 1 0 0 0 0 0 0 0 0 3 0 0 0 0 0 2 2 2 12 4 1 5 1 5 4 2 0 1 7 0 0 10 2 0 0 4 6 4 0 0 0 0 0 0 0 0 0 1 0 0 0 10 NOG23139() 0 0 0 0 0 0 1 5 0 4 13 0 0 2 0 0 0 0 5 2 1 0 11 7 2 1 7 5 9 3 3 2 5 4 2 3 0 6 0 0 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3073(Negative regulator of sigma E activity) 73 3 1 2 0 0 0 2 0 1 3 1 0 3 1 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 1 0 12 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22848() 6 5 3 5 0 0 0 13 0 3 2 2 1 0 0 0 0 0 1 0 7 3 1 1 6 0 4 2 0 0 0 5 5 1 4 12 1 0 4 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 9 NOG09822() 0 0 1 0 1 1 0 0 0 0 0 1 4 6 4 2 0 2 2 1 0 1 0 0 4 3 2 0 1 0 0 1 1 4 6 2 21 30 2 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1445(Phosphotransferase system fructose-specific component IIB) 70 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 2 0 2 1 0 2 3 3 0 2 1 10 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG22577() 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 2 0 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 0 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23558() 1 5 19 9 1 0 0 1 2 0 0 4 0 7 0 1 0 0 1 2 2 2 4 0 4 6 2 0 3 2 7 2 1 0 0 9 1 1 0 4 1 0 0 0 2 0 0 0 0 0 0 1 0 0 0 2 NOG36080() 0 2 1 3 0 0 0 0 0 0 1 0 0 0 0 0 0 6 1 1 0 1 3 1 8 0 0 4 20 4 11 0 1 3 2 13 0 0 0 4 2 11 0 0 0 0 2 0 0 0 0 4 0 0 0 0 NOG11874() 19 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5096(Vesicle coat complex, various subunits) 0 1 25 8 9 19 0 0 0 0 0 0 2 0 0 0 0 0 7 2 0 0 1 0 0 0 0 0 0 22 5 2 0 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2164(Uncharacterized conserved protein) 3 2 8 6 0 5 1 1 0 0 0 0 0 1 0 0 3 10 2 2 1 6 3 2 2 13 0 0 1 0 3 5 5 0 6 0 7 0 0 3 0 3 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG19093() 1 4 6 0 7 1 2 2 1 1 0 3 0 2 4 0 0 0 1 3 0 2 1 1 0 0 0 6 3 1 1 3 1 2 20 6 2 5 1 10 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG12186() 1 6 6 4 1 0 5 0 1 1 0 1 3 3 2 0 2 3 2 4 1 1 6 1 4 5 2 0 2 0 3 2 1 4 6 5 1 17 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG15894() 0 8 21 2 0 0 0 0 0 0 3 0 0 2 0 0 0 0 2 5 3 13 8 5 1 0 9 2 2 4 0 3 1 6 2 1 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG17881() 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 8 0 0 0 0 0 0 0 13 1 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26592() 106 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08904(Glycosyltransferase domain containing) 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 4 2 0 0 0 0 1 0 0 3 0 0 2 0 0 1 0 0 0 0 4 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32563() 11 12 0 21 1 4 0 0 0 2 0 0 0 0 0 0 0 0 0 3 7 1 13 8 6 1 4 2 0 2 0 0 0 0 0 3 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16351(Transcriptional regulator protein) 93 0 2 0 0 0 0 0 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05507(Histo-Blood group ABO protein) 1 0 0 0 0 0 0 4 0 0 0 0 2 0 0 1 2 0 0 1 3 3 4 5 3 36 1 0 6 7 3 3 1 0 0 5 2 3 0 0 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 6 NOG19081(Endonuclease/Exonuclease/Phosphatase) 2 0 5 2 1 0 2 2 0 1 1 0 0 4 0 2 0 0 3 0 3 0 4 2 0 0 2 0 0 1 1 10 7 2 25 8 1 0 4 5 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG04752() 7 0 1 0 2 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 4 0 2 0 0 0 1 2 0 3 0 7 1 2 0 0 2 36 34 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26854() 1 4 1 1 4 1 1 1 4 0 12 5 4 5 2 1 2 5 2 0 3 1 0 1 1 1 3 0 0 0 4 1 5 0 12 4 1 0 2 6 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG33834() 0 1 0 0 0 1 1 0 0 2 0 0 0 0 0 2 0 0 2 1 5 3 7 2 3 0 4 4 4 3 0 1 24 8 0 2 0 0 4 9 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG12554() 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 11 13 2 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 0 0 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17151() 5 5 9 4 0 0 2 3 1 5 2 1 0 9 0 2 0 2 1 7 1 1 0 1 3 0 1 0 1 2 0 4 5 3 9 8 3 2 0 1 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1598(Uncharacterized conserved protein) 9 0 1 0 1 2 0 0 0 0 3 0 0 3 0 0 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 12 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3757(Lyzozyme M1 (1,4-beta-N-acetylmuramidase)) 2 0 0 0 0 0 0 2 3 0 2 0 2 1 0 0 19 21 1 0 0 0 0 2 0 32 1 2 0 0 0 1 1 0 0 8 0 4 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2075(Ribosomal protein L24E) 1 3 13 7 1 0 0 0 0 0 0 0 0 3 2 0 0 0 0 4 2 9 8 3 2 6 4 0 0 3 0 5 3 3 0 5 4 2 1 2 2 3 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG4574(Serine protease inhibitor ecotin) 90 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 12 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14011(Malonate transporter MadL subunit) 52 1 8 3 1 0 1 0 0 0 0 0 2 3 0 0 0 2 3 4 1 0 4 0 0 3 0 0 0 1 1 2 0 1 3 10 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3804(Uncharacterized conserved protein related to dihydrodipicolinate reductase) 2 3 15 5 0 0 0 4 0 0 0 0 0 7 2 0 1 0 4 5 2 4 4 1 0 1 0 0 0 0 0 2 4 6 6 26 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14385() 2 4 20 3 1 0 1 0 1 1 0 0 2 2 0 0 0 0 3 1 2 11 6 4 0 1 2 2 0 0 1 8 6 1 9 7 0 5 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11364() 3 11 13 3 1 1 4 2 1 0 0 0 0 3 2 2 2 0 2 3 0 9 2 2 0 0 5 2 4 0 0 4 6 0 8 7 1 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3943(Virulence protein) 30 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 7 1 2 0 0 0 1 0 1 2 0 0 0 0 0 1 0 0 0 0 21 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2318(Uncharacterized protein conserved in bacteria) 57 2 1 3 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 0 1 0 2 2 0 0 0 0 0 0 1 1 32 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23364() 10 0 0 0 2 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 4 0 6 3 5 0 0 0 55 10 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 2 COG5270(PUA domain (predicted RNA-binding domain)) 6 4 3 1 1 0 0 3 1 0 3 1 0 3 0 5 4 5 0 0 4 4 10 1 2 5 0 2 1 2 0 4 2 0 14 4 0 6 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG11701() 1 10 21 10 1 2 0 0 1 0 0 0 0 6 0 4 1 0 0 3 8 1 6 2 8 1 4 3 1 0 0 0 2 0 0 1 2 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3253(Uncharacterized conserved protein) 3 5 6 7 0 0 0 0 0 0 0 0 0 0 0 0 4 4 1 3 3 3 2 0 1 23 0 1 0 0 4 2 0 0 2 9 4 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18677() 3 1 2 0 1 0 1 3 0 3 2 1 5 1 2 0 3 6 9 0 4 1 1 1 1 19 2 2 1 2 0 8 8 0 0 0 2 4 2 2 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG4254(Uncharacterized protein conserved in bacteria) 72 1 3 0 0 0 0 0 0 0 3 0 0 2 0 1 0 2 1 0 0 0 1 0 0 1 4 0 1 0 0 1 0 0 0 1 0 11 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21596() 101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14769() 1 2 1 1 0 0 0 4 2 4 8 2 4 6 0 0 0 0 4 0 0 0 2 0 0 0 3 4 0 0 1 5 5 4 10 6 3 6 4 8 1 3 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG5531(SWIB-domain-containing proteins implicated in chromatin remodeling) 3 1 2 0 0 1 1 3 2 0 4 0 0 4 0 4 10 10 1 3 2 0 7 0 1 6 0 0 0 2 0 3 2 2 0 8 9 8 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG14714() 1 1 2 0 0 2 0 0 1 1 0 0 2 9 2 1 0 0 5 6 1 0 0 0 3 0 2 1 3 1 0 3 3 3 9 8 2 6 11 10 3 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG05993(Fatty acid protein) 61 13 4 4 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 3 4 0 0 0 0 2 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2315(Uncharacterized protein conserved in bacteria) 11 16 15 7 0 0 0 3 1 2 1 0 1 1 0 0 0 7 5 0 2 3 2 1 2 1 0 0 1 1 3 1 1 0 0 6 1 11 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17739() 6 7 10 2 0 0 2 3 1 0 1 2 2 0 2 0 0 0 2 2 1 3 9 4 2 0 1 2 4 0 0 4 2 0 11 10 0 0 0 3 1 5 0 0 0 0 2 0 0 0 0 0 0 0 0 0 COG4275(Uncharacterized conserved protein) 95 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 3 0 0 0 0 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13284(3-5 exonuclease) 40 1 11 2 0 1 0 1 1 0 0 0 1 1 0 0 0 0 1 1 0 5 8 3 5 2 3 0 0 3 2 2 2 0 2 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09487() 2 4 7 5 0 5 3 0 0 4 0 0 3 14 5 2 4 0 6 0 3 3 2 0 1 3 3 0 0 1 0 0 0 0 0 6 5 10 0 2 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1140(Nitrate reductase beta subunit) 10 7 40 14 0 0 0 0 0 0 7 0 0 1 0 0 4 2 2 2 0 1 1 0 0 2 2 0 0 0 1 1 0 0 0 3 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16072(Phospholipase C) 0 3 14 2 0 1 0 1 0 0 0 0 0 2 0 1 0 0 0 8 4 4 12 4 2 0 0 0 4 1 2 2 10 2 0 10 0 0 3 0 5 3 0 0 0 0 0 0 0 0 0 0 0 1 0 5 NOG19658() 0 1 2 1 0 0 0 1 4 0 0 0 2 6 0 0 0 0 2 2 0 0 1 2 2 0 4 0 0 0 0 3 3 6 11 3 0 23 8 10 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 COG1777(Predicted transcriptional regulators) 0 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 7 12 12 1 2 0 4 5 8 1 3 1 7 5 0 13 0 0 0 2 2 6 0 0 0 0 0 0 0 0 0 1 0 0 0 7 NOG17815(Sulfur oxidation protein SoxX) 2 3 1 2 0 1 0 2 0 3 1 0 1 3 0 2 0 0 0 2 2 1 3 2 0 0 0 0 0 0 1 0 0 0 2 2 6 62 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38685() 2 3 1 1 1 0 0 0 0 0 0 0 0 9 0 1 0 1 4 0 2 0 0 0 0 1 2 0 1 0 0 2 1 0 0 2 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4324(Predicted aminopeptidase) 7 5 18 5 0 0 0 0 0 0 0 1 0 16 2 2 1 0 0 2 1 3 3 3 1 3 6 0 1 0 5 0 0 4 0 3 1 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG35623(HNH nucleases) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 2 1 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06060() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 4 1 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 2 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36643() 5 2 6 2 0 0 1 4 1 4 0 0 2 2 0 0 0 2 2 0 4 2 8 0 0 47 2 3 0 0 0 1 0 0 0 0 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16284() 7 0 0 1 2 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 2 0 0 0 1 0 0 0 0 0 0 0 62 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05983(Malonate decarboxylase) 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3072(Adenylate cyclase) 88 5 1 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2053(Ribosomal protein S28E/S33) 1 3 10 7 0 1 0 0 0 0 0 0 0 1 2 0 0 0 0 3 3 5 7 2 1 8 6 1 0 4 0 2 6 5 0 4 8 2 0 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG16601() 4 3 2 4 0 1 1 2 0 3 0 0 0 2 2 1 0 0 0 2 0 5 4 1 1 0 0 4 0 1 0 2 6 1 14 4 2 25 1 0 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 3 COG1907(Predicted archaeal sugar kinases) 4 6 7 9 1 0 0 1 3 0 0 0 0 0 2 1 0 0 0 1 0 0 6 2 0 0 2 0 3 0 4 0 3 0 2 19 6 16 1 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2047(Uncharacterized protein (ATP-grasp superfamily)) 3 5 12 0 0 0 0 0 0 0 0 1 0 2 2 2 0 0 0 10 2 3 13 1 4 0 2 3 1 0 0 3 9 4 0 7 4 0 3 5 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG12533() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14205() 1 1 20 4 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 1 5 2 7 2 6 3 5 2 0 0 0 0 0 0 0 2 2 28 0 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG21315() 7 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 12 6 0 0 0 0 0 2 0 8 0 0 0 0 0 6 2 0 0 0 0 38 19 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG17721() 1 1 13 7 0 3 1 0 0 0 0 0 0 2 0 2 2 0 0 0 1 0 0 3 0 1 6 0 2 0 0 4 4 0 2 6 0 37 0 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11793() 0 1 1 10 1 1 0 0 1 1 2 0 1 1 3 1 0 0 0 2 0 3 5 4 0 2 0 4 0 1 2 3 2 1 18 7 0 12 6 4 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG23643(Copper resistance protein) 94 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08035() 4 2 5 5 1 0 2 3 0 1 1 1 0 12 4 1 2 2 3 2 0 1 6 3 3 1 2 2 0 0 3 1 1 2 2 0 2 13 4 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG13533() 2 0 1 2 1 0 1 0 3 0 1 0 0 5 2 1 2 2 2 2 4 3 8 6 0 5 0 3 0 2 0 5 1 4 8 9 0 7 4 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3663(G:T/U mismatch-specific DNA glycosylase) 45 0 9 0 0 0 0 1 0 0 1 0 0 4 0 2 4 3 1 0 0 1 1 1 0 0 0 1 0 0 0 2 2 0 2 3 14 7 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11883() 0 0 4 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 13 0 9 8 5 2 0 1 3 1 2 0 8 4 6 0 5 0 0 4 8 6 4 0 0 0 0 0 0 0 0 0 2 0 0 0 7 NOG17130() 1 6 23 6 0 2 1 0 0 0 1 1 0 2 2 0 0 0 0 1 2 2 3 1 1 0 5 3 1 1 2 3 2 11 4 4 2 0 0 2 1 4 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG15919() 5 0 0 0 0 0 0 0 1 0 0 4 1 0 0 0 1 1 1 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 2 0 78 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12989() 16 3 0 2 1 1 2 0 0 1 0 0 0 0 0 0 0 0 1 1 2 2 1 3 3 0 0 1 0 0 1 10 4 0 4 0 0 28 17 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG08891() 4 4 8 3 0 3 1 4 0 4 0 0 1 2 0 1 2 5 2 0 1 0 1 2 1 6 0 1 2 0 0 4 6 0 6 6 5 14 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG4394(Uncharacterized protein conserved in bacteria) 78 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 6 7 0 0 0 0 0 0 0 8 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3620(Predicted transcriptional regulator with C-terminal CBS domains) 0 5 2 8 0 0 0 0 2 2 1 2 0 1 2 2 0 6 1 2 1 3 1 2 1 14 0 2 0 0 0 1 2 0 2 7 11 16 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11975() 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09649() 100 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13269(Lipoprotein transmembrane) 28 2 8 3 0 0 0 0 2 0 1 6 2 4 0 1 0 2 1 0 0 1 3 3 3 0 3 3 0 0 0 2 2 2 3 9 3 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11844() 0 2 1 0 0 0 0 0 0 0 3 0 0 2 0 0 3 6 4 0 1 0 0 0 0 6 0 0 0 1 0 0 0 0 0 0 0 75 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11097() 2 7 1 5 3 0 1 4 0 0 1 1 2 4 6 3 0 0 4 0 0 1 3 1 2 0 4 0 1 2 2 4 0 2 6 7 3 19 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04766(Methylase/Helicase) 9 5 7 2 1 3 0 6 0 0 2 0 6 8 0 0 2 2 0 1 4 0 2 0 0 0 5 0 3 1 2 1 0 0 0 2 2 19 0 3 2 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 NOG19712(Translocation protein) 0 1 9 2 0 0 0 2 0 3 0 2 8 2 0 0 0 0 0 4 5 0 3 0 0 0 6 0 1 0 4 3 1 3 7 3 3 9 0 6 2 5 1 0 0 0 0 0 2 0 0 1 0 0 0 6 NOG16986(Coenzyme PQQ synthesis) 43 1 2 1 1 0 1 4 0 0 0 1 0 9 2 4 6 3 1 0 0 3 1 0 0 3 0 0 3 0 0 2 0 1 4 0 0 5 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3252(Methenyltetrahydromethanopterin cyclohydrolase) 5 9 8 8 0 1 0 3 2 0 0 0 0 0 1 3 3 0 1 2 2 1 5 2 0 0 4 0 1 0 0 2 5 0 4 21 0 9 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0301(Thiamine biosynthesis ATP pyrophosphatase) 42 4 3 0 0 0 0 0 0 0 0 0 0 5 0 4 0 0 1 2 0 4 2 0 0 2 0 0 0 0 0 3 4 0 0 4 21 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1581(Archaeal DNA-binding protein) 1 4 11 5 0 0 0 0 0 0 0 1 0 6 4 0 0 0 1 8 2 0 0 0 1 12 6 0 3 0 0 3 7 4 0 3 14 0 3 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3130(Ribosome modulation factor) 16 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 1 1 1 0 0 2 1 1 0 0 0 0 0 0 0 0 2 0 1 8 66 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2263(Predicted RNA methylase) 0 0 3 1 2 0 0 0 0 2 0 1 0 6 0 1 2 0 1 5 8 5 4 2 3 0 1 2 4 1 1 4 9 4 2 8 4 2 4 0 2 3 0 0 0 0 0 0 0 0 0 3 0 1 0 3 NOG07972() 102 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4959(Type IV secretory pathway, protease TraF) 91 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 2 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06204() 98 0 0 1 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06487() 54 0 1 0 1 0 0 2 0 3 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 2 1 1 0 0 2 4 2 8 3 0 6 0 7 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4823(Abortive infection bacteriophage resistance protein) 61 3 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5092(N-myristoyl transferase) 0 0 0 2 2 3 0 28 17 0 0 4 10 2 2 6 2 2 10 4 1 0 0 0 0 2 0 0 2 0 0 0 1 0 0 1 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10061() 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 28 7 1 0 0 0 0 0 0 55 0 0 2 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1631(Ribosomal protein L44E) 0 4 12 6 2 0 0 0 0 0 0 1 0 0 4 0 0 0 0 5 2 6 6 1 2 2 4 4 3 1 1 4 4 0 0 6 2 1 4 2 1 4 0 0 0 0 0 0 0 0 0 4 0 0 0 6 NOG08647(Sulfur oxidation protein) 1 4 3 3 1 1 0 7 0 2 1 0 0 2 2 1 0 0 1 0 1 0 1 0 0 0 2 0 0 0 0 1 0 0 2 4 13 47 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17404() 2 4 2 6 1 4 1 1 0 0 2 0 0 3 2 1 0 1 0 2 2 2 5 3 1 0 7 3 4 0 1 7 6 0 8 2 2 3 1 5 3 1 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG17184() 4 2 0 1 0 0 0 10 2 0 2 0 2 2 0 0 0 0 2 0 0 0 0 0 0 0 2 0 0 3 0 1 0 0 0 0 0 69 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3449(DNA gyrase inhibitor) 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1548(Predicted transcriptional regulator/sugar kinase) 4 8 4 8 0 0 0 1 1 0 0 0 0 0 2 1 2 4 1 2 0 2 4 2 1 1 2 2 1 0 2 5 1 2 6 12 0 20 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4308(Limonene-1,2-epoxide hydrolase) 1 2 9 1 1 0 1 0 0 0 3 0 0 8 0 0 6 8 7 5 7 3 4 0 0 13 0 0 2 0 1 0 0 0 1 15 0 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17666() 0 2 1 4 0 0 0 0 0 0 4 0 0 3 0 1 2 6 1 2 0 5 1 0 4 22 1 0 3 0 0 2 4 3 1 8 3 5 1 0 4 0 0 1 0 0 0 0 0 0 0 3 0 0 0 6 NOG16479() 0 0 1 0 2 2 1 0 2 0 0 1 0 3 2 1 0 5 3 3 1 0 1 1 1 0 2 5 1 0 0 7 8 4 6 16 3 6 3 5 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 4 NOG16018() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 6 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1735(Predicted metal-dependent hydrolase with the TIM-barrel fold) 4 7 11 6 0 2 1 0 0 0 0 0 0 4 0 1 6 5 2 3 1 2 10 0 2 22 0 2 0 1 0 2 0 0 0 4 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12535() 0 0 0 0 0 0 0 0 0 0 4 0 0 6 0 0 1 3 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17143(Minor curlin subunit CsgB) 103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06390() 1 2 2 0 0 1 4 1 1 0 0 3 1 2 0 0 2 0 4 1 2 0 0 1 0 2 0 2 2 1 1 2 1 0 0 6 0 46 0 6 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG15848(Preprotein translocase) 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 13 8 1 0 0 0 0 0 0 27 0 0 0 0 0 1 1 0 0 2 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11500(Exported protein) 96 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04732() 5 1 1 1 4 2 1 0 0 0 0 0 0 2 0 0 0 0 0 0 2 0 1 0 0 2 1 0 0 2 0 7 1 4 0 2 0 25 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3125(Heme/copper-type cytochrome/quinol oxidase, subunit 4) 79 6 1 0 0 0 0 2 0 0 0 0 0 0 2 0 2 1 1 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3652(Predicted outer membrane protein) 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23865() 3 5 13 3 2 0 1 3 0 4 0 0 0 2 0 0 0 0 1 1 0 5 2 2 0 3 3 1 0 1 2 3 3 2 9 15 0 12 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23924() 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4320(Uncharacterized protein conserved in bacteria) 72 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 7 5 2 0 0 0 0 1 0 2 0 0 0 2 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26372() 2 1 8 3 0 1 1 0 0 0 3 2 0 2 7 0 2 0 1 1 0 2 6 1 3 0 2 6 1 0 2 0 0 2 6 20 4 6 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG23155() 3 1 2 5 0 0 1 2 0 1 2 0 3 8 2 5 6 1 2 5 1 2 4 1 1 3 1 2 1 3 0 1 1 4 2 19 4 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2215(ABC-type uncharacterized transport system, permease component) 10 2 2 0 2 0 0 1 3 0 0 0 2 7 0 0 1 3 2 1 0 1 3 0 3 7 0 0 2 1 5 3 3 2 0 4 4 23 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG04001() 0 1 1 0 0 1 0 3 0 0 2 5 2 8 0 1 9 8 5 0 3 0 2 1 0 4 0 4 0 1 0 3 4 2 9 11 2 2 2 2 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG21572() 79 1 2 0 1 0 1 0 0 0 0 0 0 2 0 0 0 2 3 0 0 0 1 0 0 2 0 0 0 2 0 0 0 0 0 0 0 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3258(Cytochrome c) 44 0 1 4 0 0 0 0 0 0 5 0 0 2 0 1 3 1 0 1 0 0 0 1 0 5 2 2 1 0 0 1 2 0 4 2 2 10 2 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1715(Restriction endonuclease) 18 1 1 3 0 0 0 0 0 0 3 0 0 6 0 1 2 0 1 4 2 1 2 1 2 6 1 0 0 5 2 0 0 0 2 2 2 33 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 NOG12780() 5 4 0 7 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 6 7 16 4 6 1 0 4 9 4 8 8 3 0 0 0 0 0 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2839(Uncharacterized protein conserved in bacteria) 0 1 4 7 3 0 1 5 1 1 2 0 1 3 0 0 0 0 0 3 2 1 1 0 2 2 1 2 1 1 3 3 6 2 17 11 3 0 1 3 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG09442() 0 3 2 4 1 0 0 2 0 0 0 0 0 2 0 0 7 4 1 0 6 0 5 6 3 18 1 3 2 0 1 2 0 2 0 0 2 20 1 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG30005() 2 6 2 6 1 0 1 0 0 0 0 0 0 42 22 0 0 0 0 0 3 0 0 8 0 0 4 0 0 0 1 0 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04748() 9 1 0 2 2 1 2 1 0 0 0 0 0 0 0 0 0 0 2 2 3 1 0 0 0 0 1 1 1 5 0 1 2 0 0 0 0 46 14 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG34722() 102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26377() 2 4 2 4 0 0 1 3 0 5 1 0 2 0 0 1 3 2 1 1 0 7 7 2 5 2 3 4 2 0 2 4 0 0 6 4 5 14 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3237(Uncharacterized protein conserved in bacteria) 64 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 0 2 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4389(Site-specific recombinase) 93 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10767() 1 4 4 1 0 0 2 2 1 0 0 3 0 0 4 0 4 2 0 0 1 2 2 0 5 0 1 0 0 0 0 1 3 0 4 7 4 34 2 2 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 3 COG1958(Small nuclear ribonucleoprotein (snRNP) homolog) 0 5 23 5 4 5 0 1 0 0 0 0 0 3 2 0 1 2 1 3 2 1 2 0 0 14 1 0 0 8 0 1 0 0 0 4 12 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1439(Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module) 0 3 13 3 0 3 0 0 0 0 0 1 2 1 4 1 0 0 3 2 1 8 6 2 0 8 1 1 0 1 0 2 10 4 0 5 0 0 2 8 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG2042(Uncharacterized conserved protein) 1 4 11 1 0 0 0 2 0 0 0 0 0 0 2 0 0 0 0 5 2 3 5 5 4 10 0 2 9 1 1 4 5 0 0 2 1 0 1 1 7 4 0 0 0 0 0 0 0 0 0 1 0 0 0 8 NOG14746() 0 0 0 1 0 0 1 2 1 1 2 0 3 8 0 0 0 0 1 2 0 0 0 1 0 0 5 3 2 0 0 6 3 3 11 8 3 17 3 6 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG4242(Cyanophycinase and related exopeptidases) 5 3 3 1 0 1 0 0 0 0 1 2 0 0 2 0 8 14 0 2 0 1 4 0 4 18 0 0 0 0 2 0 1 3 2 2 2 10 3 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06105() 1 8 28 3 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 10 2 0 8 1 3 2 2 7 2 0 1 2 0 0 4 1 0 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG11247() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1713(Predicted HD superfamily hydrolase involved in NAD metabolism) 0 6 3 1 1 0 3 4 6 0 0 3 0 0 4 0 0 0 0 4 0 1 5 1 3 1 1 0 3 0 3 4 1 0 4 4 2 28 0 3 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3521(Uncharacterized protein conserved in bacteria) 76 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4268(McrBC 5-methylcytosine restriction system component) 16 5 0 1 0 0 3 1 0 0 3 4 0 3 0 4 1 2 2 0 3 0 1 0 2 3 5 6 3 0 1 0 0 0 4 0 5 19 1 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 1 COG3567(Uncharacterized protein conserved in bacteria) 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 6 0 0 0 0 0 0 3 0 0 0 3 0 2 5 2 0 0 0 74 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32751() 3 5 4 8 0 2 1 0 0 0 0 1 0 0 2 0 3 4 0 0 1 0 5 1 5 18 5 2 2 0 4 6 3 3 2 1 3 2 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3271(Predicted double-glycine peptidase) 54 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 1 2 0 1 0 2 0 0 0 0 2 0 34 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18595() 25 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08618() 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 1 0 0 0 0 0 91 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09333() 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 91 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5516(Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding) 94 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4728(Uncharacterized protein conserved in bacteria) 45 1 0 2 1 0 1 1 1 0 2 3 0 4 0 0 3 1 1 0 1 0 2 0 0 4 0 2 1 0 0 0 3 0 6 1 12 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3766(Predicted membrane protein) 53 6 2 7 0 1 1 0 0 0 0 0 0 2 0 0 0 0 1 5 0 2 1 4 3 0 1 0 4 0 1 2 0 0 2 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29187() 1 0 3 3 0 6 3 2 1 1 5 1 0 7 0 0 4 1 5 2 3 2 2 0 1 5 0 3 0 1 0 5 1 2 2 7 2 17 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06145() 46 1 0 0 0 0 0 0 0 0 1 0 0 0 0 2 2 4 0 0 0 0 1 0 0 1 3 0 0 1 0 0 0 0 0 0 11 26 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4991(Uncharacterized protein with a bacterial SH3 domain homologue) 100 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4689(Acetoacetate decarboxylase) 48 1 2 4 0 0 0 0 0 0 0 1 0 5 2 1 1 2 0 2 0 2 4 0 0 4 2 0 0 0 2 0 0 0 0 3 2 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14850() 96 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG34809() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04409(Protein involved in taste transduction) 0 1 8 2 1 9 0 4 0 1 0 0 0 0 0 0 2 1 2 4 2 0 10 1 5 2 4 6 1 4 0 0 3 0 2 8 13 0 0 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11867() 1 4 3 6 0 0 0 4 6 0 0 1 2 0 0 0 6 2 2 1 3 4 2 2 2 13 1 2 1 0 3 5 4 0 4 6 2 2 2 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19672() 2 1 0 2 0 0 0 3 1 4 0 0 4 3 2 1 1 0 2 2 0 1 1 0 1 0 2 4 2 0 0 4 3 4 6 6 2 20 4 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG16522() 2 0 2 1 0 0 0 0 0 0 0 0 0 2 0 2 7 36 0 0 0 1 1 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4186(Predicted phosphoesterase or phosphohydrolase) 0 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 22 2 0 0 0 0 0 0 0 53 0 2 0 0 0 0 1 0 0 0 4 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08602() 88 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06255(Biofilm PGA synthesis protein pgaA) 99 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1829(Predicted archaeal kinase (sugar kinase superfamily)) 0 6 6 8 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 9 0 8 1 0 5 3 2 4 1 4 7 6 1 2 10 2 0 0 6 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG17656() 0 1 3 1 0 0 3 7 2 0 0 2 0 1 0 0 0 0 1 0 4 2 2 3 3 0 7 2 1 0 3 3 5 0 6 4 0 15 3 10 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG12193(Phosphatidylinositol protein) 99 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15962() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 4 1 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18358() 19 3 1 2 4 3 4 4 0 0 0 1 0 0 2 5 0 4 3 3 0 2 2 2 1 3 4 2 0 0 2 3 2 3 2 0 2 6 3 0 0 2 0 0 0 0 0 0 0 0 0 1 1 0 0 0 COG1983(Putative stress-responsive transcriptional regulator) 37 4 2 0 2 0 2 4 2 1 1 0 0 0 0 0 4 4 1 0 0 1 1 1 2 5 1 0 0 0 0 5 0 0 2 2 9 5 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG34420() 7 3 0 5 2 3 2 0 0 0 0 0 0 0 0 0 0 0 0 1 6 2 13 6 9 0 2 0 6 4 5 4 1 0 6 1 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1901(Uncharacterized conserved protein) 0 0 7 4 0 0 0 0 0 0 1 0 1 8 4 2 0 2 2 4 2 6 10 4 0 1 0 2 3 1 1 3 5 0 0 5 7 0 1 4 7 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG30885() 99 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3529(Predicted nucleic-acid-binding protein containing a Zn-ribbon domain) 16 0 0 0 0 0 0 0 0 1 2 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 1 0 1 0 0 0 0 8 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11870(Tail tape protein) 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08750() 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 24 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4317(Uncharacterized protein conserved in bacteria) 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09991() 73 1 0 7 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 0 3 0 0 0 1 1 0 0 0 0 6 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14092() 99 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06913(Serine/Threonine-Protein kinase 31 (EC 2.7.11.1)) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3768(Predicted membrane protein) 56 3 1 1 0 0 0 2 0 0 0 0 0 6 0 0 0 0 1 0 0 0 1 2 0 0 0 0 0 0 1 1 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG18023() 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12919() 9 1 0 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 10 8 13 10 4 0 0 3 6 8 4 5 0 1 0 2 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13368() 69 10 5 1 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17147(Major capsid protein) 10 0 2 0 0 0 0 13 1 0 0 0 8 0 0 0 0 2 0 0 0 0 0 0 0 2 1 2 0 0 0 0 0 0 0 0 0 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG10321(Transposase) 84 3 2 3 0 1 0 0 0 0 0 0 0 0 2 0 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18149() 92 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14719(Ankyrin repeats) 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22599(Esterase/Lipase) 0 2 7 0 0 0 1 0 3 2 2 2 1 0 2 1 0 1 0 0 1 0 6 1 1 1 2 2 2 0 2 10 0 0 22 6 0 9 2 3 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14540() 33 4 3 1 0 0 0 0 2 1 0 2 0 2 0 3 3 0 2 1 0 0 1 1 0 0 3 2 0 0 0 4 2 2 8 5 0 10 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG28307() 2 2 4 6 7 1 1 4 2 0 0 1 0 2 0 0 0 0 1 1 5 1 0 1 0 0 2 1 2 0 4 14 2 3 5 5 0 0 5 9 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19747(Cytochrome c protein) 0 3 4 4 0 0 1 1 0 1 4 0 1 4 0 1 0 0 1 2 4 3 0 0 0 0 5 0 1 0 0 0 0 0 0 0 21 34 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG36031() 2 3 4 5 1 4 0 4 0 2 0 0 2 2 1 0 0 0 3 6 3 1 1 0 0 2 0 2 0 2 1 5 0 2 0 7 6 20 3 2 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3747(Phage terminase, small subunit) 13 0 1 0 0 0 0 0 1 0 4 0 0 3 0 0 0 6 4 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 64 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1779(C4-type Zn-finger protein) 0 2 1 0 1 0 0 0 0 0 0 0 0 1 3 2 0 0 4 4 7 8 7 4 3 0 1 3 0 4 2 2 4 2 0 3 2 0 3 1 5 10 0 0 0 0 0 0 0 0 0 1 0 0 0 9 NOG12616(Transcriptional regulator protein) 45 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 9 1 0 0 0 0 0 0 26 0 0 1 0 0 1 0 0 0 2 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19653() 2 1 2 0 0 1 0 1 0 0 3 0 0 10 0 3 0 0 6 0 0 0 1 2 0 0 3 0 0 0 1 5 2 7 15 7 0 11 7 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3149(Type II secretory pathway, component PulM) 82 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 1 0 4 0 0 0 0 0 0 0 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14765() 88 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13977() 3 5 7 7 0 1 1 2 2 0 0 6 0 1 0 0 0 1 1 3 1 1 2 4 4 1 2 2 2 0 0 4 2 0 8 13 2 2 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20037() 36 2 4 0 0 0 1 0 0 1 0 0 1 11 0 0 0 2 2 0 0 0 1 0 0 0 3 1 1 0 0 3 0 2 9 7 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG11201() 2 5 0 6 2 0 0 2 0 0 0 2 4 8 4 4 3 1 5 5 1 1 2 0 3 2 1 0 1 0 2 2 3 3 4 9 1 0 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG09608(Outer membrane porin protein) 83 0 0 0 0 0 0 0 0 0 1 2 0 6 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5639(Uncharacterized conserved small protein) 96 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG36229() 3 1 3 1 0 0 1 0 0 0 0 0 0 1 9 3 2 0 2 6 4 0 8 6 0 0 0 6 3 0 2 4 0 4 4 17 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG11772() 0 3 5 3 0 0 0 15 1 2 1 0 4 4 0 3 0 2 6 0 2 1 4 4 0 1 1 0 0 0 0 5 1 0 4 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14559() 2 0 1 3 3 0 3 0 1 1 3 1 0 2 2 0 0 0 2 1 0 4 3 3 0 1 0 0 0 0 2 9 1 3 11 9 4 6 1 12 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09960(Protein involved in stilbene, coumarine and lignin biosynthesis) 0 1 2 1 0 0 0 0 0 0 5 0 0 1 3 0 0 0 0 2 0 10 0 0 0 4 2 2 0 4 0 0 1 0 0 0 2 57 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12573(ABC transporter protein) 0 0 0 0 0 0 0 0 5 0 2 4 3 7 2 2 3 2 1 0 0 0 0 0 0 23 2 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1096(Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)) 1 4 6 2 0 1 0 0 0 3 0 1 0 2 0 0 0 0 0 1 9 6 6 1 0 9 0 2 2 2 0 6 7 2 0 6 2 0 4 2 4 6 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2152(Predicted glycosylase) 3 0 1 1 0 1 1 0 1 2 2 0 0 2 0 3 5 6 1 0 0 0 0 0 0 10 0 0 0 1 2 0 0 0 0 0 15 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04279(Beta-N-Acetylhexosaminidase) 1 1 5 0 0 0 0 6 3 0 6 1 0 4 0 3 0 0 0 0 3 1 0 3 0 0 5 3 3 0 2 2 2 2 21 6 0 3 1 6 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG16508() 41 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1334(Uncharacterized flagellar protein FlaG) 46 1 3 2 0 0 0 0 1 2 3 0 0 4 0 0 3 4 1 2 1 0 4 2 1 4 1 0 0 0 0 0 0 0 5 0 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4291(Predicted membrane protein) 46 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 1 2 0 0 0 0 0 1 0 6 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3338(Carbonic anhydrase) 14 0 1 0 1 1 0 2 0 2 0 0 0 2 0 1 14 9 1 0 1 0 0 1 0 11 0 0 0 0 0 0 0 2 0 1 1 30 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1997(Ribosomal protein L37AE/L43A) 2 4 9 4 0 0 0 0 0 0 0 0 0 3 4 0 2 0 0 4 5 3 5 3 0 6 1 2 2 1 3 2 2 0 0 2 9 0 2 3 2 5 1 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG06209() 8 1 13 2 1 0 2 4 0 2 0 2 0 2 0 0 1 4 2 0 0 2 2 1 2 1 0 5 4 0 0 3 4 2 3 7 6 4 2 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG17562() 0 5 3 4 4 0 4 1 0 2 1 2 0 0 2 0 0 0 2 0 1 0 1 0 0 3 0 3 0 0 2 1 2 4 28 3 6 0 0 4 1 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 NOG09594(Cytochrome c protein) 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08892() 0 3 5 3 0 0 0 0 0 0 0 0 2 0 0 1 0 2 3 5 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 65 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11925() 54 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 3 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4570(Holliday junction resolvase) 6 2 0 0 0 0 0 2 0 2 1 1 1 1 0 0 1 1 14 1 0 0 3 0 0 3 2 0 0 0 0 0 6 0 0 2 0 45 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG14576() 0 19 7 17 20 4 0 0 0 0 0 0 0 0 2 0 0 0 4 0 1 3 0 2 1 0 0 0 0 7 0 0 0 0 0 2 2 4 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11516() 2 0 0 8 0 1 3 0 1 2 2 0 0 1 0 2 0 0 3 1 2 0 4 3 3 0 2 4 1 0 0 1 3 6 16 10 2 1 7 0 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG15986() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 14 3 1 0 0 0 0 0 38 0 0 0 0 0 0 0 2 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14743(Acyl carrier protein) 3 1 2 2 0 0 0 1 0 2 0 0 0 6 2 2 0 0 2 4 2 0 1 1 2 0 1 2 1 0 1 4 2 4 11 8 0 16 3 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13677() 0 2 33 6 0 0 0 2 1 0 0 0 2 0 0 0 0 2 0 1 2 4 7 2 6 0 2 2 0 2 0 1 1 1 5 4 0 3 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12531(Secreted protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 15 0 0 0 0 0 1 0 32 2 0 0 0 0 0 1 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG31491() 2 0 3 3 0 0 2 2 0 0 6 0 0 1 0 2 0 0 5 0 0 3 5 1 4 2 2 0 0 1 3 2 0 0 0 5 2 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG17198() 21 5 2 1 0 0 0 7 4 3 4 1 0 3 3 4 3 0 1 0 0 1 5 1 1 0 0 1 0 0 0 2 1 0 9 4 0 2 2 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4284(UDP-glucose pyrophosphorylase) 3 5 8 3 4 9 2 0 0 6 0 0 4 0 2 0 4 3 10 3 0 0 0 0 0 0 0 0 0 6 0 3 0 0 0 0 2 18 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 NOG14290() 2 3 2 4 0 2 1 5 1 1 0 2 0 4 0 1 5 7 0 7 0 0 0 0 0 4 1 1 3 1 4 2 1 2 6 7 2 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16456() 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 3 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14016() 5 0 1 0 0 1 0 8 1 1 17 0 0 1 0 1 0 0 19 1 0 0 1 2 1 0 2 2 0 0 0 5 5 0 4 2 5 8 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3327(Phenylacetic acid-responsive transcriptional repressor) 6 3 2 1 0 0 0 0 0 0 0 0 2 10 2 5 2 2 6 1 0 0 0 0 0 2 0 0 0 0 0 1 2 4 2 10 13 15 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5652(Predicted integral membrane protein) 71 0 1 0 0 0 0 0 0 1 0 0 0 2 0 0 11 5 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10599() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27 36 0 0 1 0 0 0 0 32 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09476() 19 1 0 0 8 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 2 0 0 1 0 7 1 3 0 0 0 28 19 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11548() 1 2 1 2 1 0 0 0 0 0 0 1 0 1 0 1 4 2 2 0 2 0 0 0 0 1 0 0 1 0 0 0 0 0 2 14 26 30 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14830() 97 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33224() 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4244(Predicted membrane protein) 9 4 0 1 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 1 0 0 12 0 0 13 4 0 35 8 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG28037() 95 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4671(Predicted glycosyl transferase) 1 3 9 6 0 1 0 0 0 0 0 0 0 9 2 1 1 0 2 1 0 1 2 1 3 0 0 0 1 0 0 1 0 0 4 0 2 41 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1791(Uncharacterized conserved protein, contains double-stranded beta-helix domain) 10 1 0 2 3 0 0 2 0 0 1 2 0 0 0 0 0 0 0 3 3 0 1 1 0 2 2 0 0 1 1 5 2 0 2 3 0 32 14 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1422(Predicted membrane protein) 0 0 7 1 0 0 0 0 0 0 0 0 2 1 0 0 2 0 0 1 1 3 5 3 1 6 7 7 2 2 1 4 4 2 0 8 2 0 1 2 4 0 2 0 0 0 0 0 0 0 0 5 0 0 0 10 NOG14885() 0 1 6 0 0 0 0 0 0 0 0 0 0 4 2 1 0 0 0 6 3 4 11 1 1 0 7 2 1 2 0 5 6 3 0 7 1 0 3 0 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 14 NOG13966() 9 3 6 0 0 0 0 0 1 0 0 3 0 0 2 1 2 0 0 4 5 9 1 2 0 3 0 3 2 1 0 4 2 2 2 9 4 6 0 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG09309() 4 13 10 8 0 0 1 0 1 3 0 0 0 0 0 0 4 2 0 2 2 1 2 0 8 2 0 0 4 0 1 4 1 1 7 4 0 0 4 0 1 2 0 1 0 0 0 0 0 0 0 3 0 0 0 0 COG4461(Uncharacterized protein conserved in bacteria, putative lipoprotein) 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2078(Uncharacterized conserved protein) 1 4 4 8 0 1 0 2 0 0 0 0 0 0 3 3 1 0 0 2 6 0 3 0 3 16 1 0 2 2 0 0 0 0 0 0 14 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16216() 6 4 2 4 0 0 2 2 2 4 0 0 0 2 2 0 1 0 1 2 3 1 6 0 2 0 2 1 2 0 0 6 3 2 13 11 0 0 4 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38733() 9 2 0 5 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 10 4 3 0 0 0 2 8 2 3 0 0 4 0 0 17 11 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3256(Nitric oxide reductase large subunit) 79 1 1 2 0 0 0 0 0 0 0 0 0 2 2 0 1 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36100() 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 2 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18009() 6 3 0 1 0 2 0 1 2 3 7 0 1 11 2 1 12 4 4 0 0 3 0 2 0 10 1 0 0 0 0 1 0 2 0 2 2 6 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12628() 1 1 1 0 0 1 1 0 0 0 0 1 0 2 0 0 0 0 0 1 0 0 2 1 2 1 3 0 1 0 0 1 0 2 3 1 0 63 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 NOG23615() 2 12 8 2 14 0 0 0 0 0 0 0 0 8 25 0 0 0 0 0 1 0 0 0 0 0 0 2 0 2 0 0 0 3 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14650() 50 0 0 0 0 0 0 2 0 2 0 0 0 7 2 6 8 3 4 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 4 2 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21756() 0 4 1 0 2 0 1 1 2 0 1 1 3 3 0 1 0 0 1 1 1 0 1 1 0 1 1 0 1 1 0 0 1 0 2 0 0 61 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14553() 0 0 1 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 2 2 2 0 1 4 0 2 0 0 0 0 0 0 2 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 COG0298(Hydrogenase maturation factor) 26 0 0 0 0 1 0 0 0 0 0 0 0 2 3 1 1 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG34725() 18 9 11 12 0 0 2 0 2 3 1 1 0 1 1 2 0 0 3 2 1 0 3 0 0 1 0 1 3 0 2 3 2 1 0 1 2 4 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG1518(Uncharacterized protein predicted to be involved in DNA repair) 15 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 1 2 0 0 0 2 2 1 0 0 0 1 63 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2733(Predicted membrane protein) 67 6 0 1 0 0 0 0 0 0 0 0 1 0 0 0 2 4 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 5 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 NOG12660() 0 0 3 0 1 0 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3728(Phage terminase, small subunit) 18 6 10 5 1 0 0 0 0 0 2 0 0 2 0 0 0 0 1 2 1 2 1 1 0 0 0 0 0 0 0 1 1 0 2 2 1 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14555() 1 0 4 3 0 0 0 0 0 0 0 0 0 1 0 1 0 4 2 2 2 0 2 1 0 4 0 1 0 1 0 0 0 0 4 6 2 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21754() 4 5 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 1 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08640() 4 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 4 2 0 0 0 0 3 1 3 2 3 1 0 2 6 5 37 8 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG18240(Ethyl tert-butyl ether degradation protein) 50 2 2 2 1 0 0 0 2 0 0 1 0 2 3 0 0 0 0 0 4 1 0 1 0 7 0 2 0 0 2 3 0 0 0 1 0 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07797() 90 3 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12506() 0 4 3 4 0 0 0 6 0 5 0 0 2 4 0 2 0 8 2 2 0 0 0 0 0 0 4 4 0 0 4 0 2 2 7 2 2 23 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG04710() 4 0 5 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3 2 0 0 0 3 0 2 2 0 0 2 0 0 0 63 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17530(Transcriptional regulator protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 4 0 0 0 0 0 1 0 0 0 0 4 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2452(Predicted site-specific integrase-resolvase) 0 0 0 0 0 0 0 3 1 0 0 0 1 4 0 0 7 17 1 0 0 0 1 0 0 14 0 0 0 0 0 0 0 0 0 0 23 21 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19115() 1 2 5 1 3 3 2 5 2 1 1 2 1 1 0 1 0 0 2 0 1 1 3 3 4 0 1 2 3 1 0 8 1 1 4 18 0 0 4 2 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG28878() 8 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 6 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22584() 1 0 4 1 0 0 1 0 0 0 0 0 1 1 0 0 0 0 1 2 8 5 8 3 3 0 1 5 5 0 3 3 1 2 10 16 2 2 0 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG4690(Dipeptidase) 9 0 6 2 2 3 2 0 0 0 0 0 0 1 0 5 2 0 2 0 2 0 1 0 0 4 1 0 0 8 0 0 0 0 0 32 2 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG20002() 2 3 5 1 1 2 0 4 1 2 0 0 2 5 2 1 0 1 3 2 1 1 3 3 5 0 5 4 0 0 1 2 3 0 4 8 0 5 0 0 2 8 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG37981(Ribonuclease P protein component) 3 0 2 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 2 1 1 0 2 1 1 8 3 6 0 0 2 1 0 32 17 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG19023() 92 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5342(Invasion protein B, involved in pathogenesis) 0 4 2 3 0 0 0 2 1 0 1 0 3 4 2 0 0 0 0 2 4 0 0 2 0 0 2 2 0 0 0 5 5 4 6 4 0 27 4 2 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG38148() 89 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 COG3304(Predicted membrane protein) 43 0 1 0 2 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 1 2 0 2 3 0 0 0 0 3 2 0 3 0 0 15 11 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16670() 0 5 7 2 0 3 0 0 1 0 0 0 0 8 4 1 1 2 3 2 4 4 3 1 0 10 4 2 0 1 1 1 0 3 0 9 4 3 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3631(Ketosteroid isomerase-related protein) 10 6 2 4 0 0 0 6 1 2 0 0 5 5 2 1 6 0 3 0 3 0 2 4 3 0 3 1 1 2 0 0 3 0 6 5 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3187(Heat shock protein) 65 1 1 0 0 0 0 0 0 0 1 0 0 1 0 0 0 2 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2336(Growth regulator) 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2140(Thermophilic glucose-6-phosphate isomerase and related metalloenzymes) 50 1 8 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 1 2 0 2 3 5 0 0 0 1 1 0 1 6 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG23576() 2 4 3 4 0 0 0 2 0 2 0 1 4 1 2 3 0 2 6 0 0 0 4 0 4 0 3 2 3 0 2 2 0 8 2 14 0 10 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33584() 1 2 2 1 1 0 1 0 0 0 0 0 3 39 26 0 2 0 0 0 0 1 0 9 0 1 0 1 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36097() 78 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14742() 1 0 0 2 0 0 2 0 0 1 0 0 0 11 2 0 0 0 2 3 4 2 4 1 0 0 1 0 0 0 0 4 4 1 14 14 0 7 3 3 5 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG33244() 0 5 2 1 0 0 0 11 0 10 0 0 3 0 2 3 0 0 9 0 0 2 1 2 0 0 0 0 3 0 0 3 0 0 4 1 0 26 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG18220() 3 5 2 1 4 0 1 4 0 2 1 0 1 2 0 3 0 0 8 3 0 2 3 2 0 0 0 2 2 0 0 5 6 0 8 3 4 2 6 3 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13470() 0 0 0 0 0 0 0 0 0 0 11 0 2 0 0 0 0 0 6 0 0 0 0 0 0 2 1 0 0 1 2 1 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08912() 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17751() 39 0 0 0 0 0 0 0 0 1 1 0 0 0 0 1 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25027() 85 0 0 0 0 0 0 0 1 0 1 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG19770() 1 2 11 6 0 0 0 0 0 2 0 0 0 4 2 3 4 5 3 4 3 1 5 0 1 5 0 0 1 0 0 12 6 0 0 9 0 0 0 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 NOG08901() 7 6 4 7 1 1 2 0 0 0 0 0 0 2 2 0 1 4 1 2 1 1 8 3 7 1 2 1 2 0 1 0 2 0 5 14 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2181(Nitrate reductase gamma subunit) 9 4 1 2 0 1 0 2 1 2 0 0 0 3 2 0 1 4 4 0 1 3 4 0 1 0 6 1 0 0 1 1 3 0 4 14 4 12 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG07981() 54 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12827(Structural constituent of cell wall protein) 1 4 23 3 2 0 0 1 2 0 0 4 0 3 2 1 0 0 1 4 2 3 2 0 2 5 2 0 0 2 5 2 2 0 2 5 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4706(Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase) 85 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32109() 2 1 2 9 1 3 3 0 0 4 5 0 1 6 2 3 2 0 4 1 2 3 3 3 1 1 2 0 2 0 0 1 4 0 8 7 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG19683() 1 1 1 1 1 0 1 1 0 4 0 1 0 8 0 1 0 0 1 2 2 1 2 1 0 0 0 5 0 0 0 4 3 2 12 9 1 16 2 3 1 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG20287(Alpha/Beta hydrolase) 25 1 3 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 2 2 1 3 1 7 2 0 3 0 0 0 0 0 3 3 12 5 0 7 1 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG14001() 0 2 1 5 1 1 3 4 0 0 0 0 0 0 0 1 2 0 1 0 0 3 3 2 1 0 0 0 5 0 0 1 0 0 0 1 1 53 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5147(Myb superfamily proteins, including transcription factors and mRNA splicing factors) 0 7 12 3 2 16 0 1 3 6 0 0 2 0 0 1 0 1 6 0 0 1 0 0 0 0 0 0 2 13 2 1 0 0 0 4 2 4 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3907(PAP2 (acid phosphatase) superfamily protein) 34 4 5 0 0 0 0 1 1 2 1 0 0 7 0 0 15 1 3 0 2 0 1 3 0 3 6 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2923(Uncharacterized protein involved in the oxidation of intracellular sulfur) 27 6 5 2 0 0 0 0 1 0 0 0 0 1 2 0 2 1 3 2 3 2 4 0 2 0 0 0 0 0 0 2 2 0 7 9 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07960() 2 2 5 3 0 0 0 2 0 0 0 1 0 2 0 0 2 0 0 4 1 2 3 1 0 11 3 8 1 0 0 3 2 2 5 10 0 3 3 7 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG04738(CO2 hydration protein) 11 2 0 1 1 2 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 1 2 0 2 0 8 1 0 0 0 0 39 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 COG1284(Uncharacterized conserved protein) 12 9 10 2 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 1 3 0 2 1 0 2 5 0 0 0 0 0 0 0 0 0 11 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3932(Uncharacterized ABC-type transport system, permease components) 7 1 3 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 3 0 0 0 0 3 0 2 0 0 1 1 0 0 0 2 2 63 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1823(Predicted Na+/dicarboxylate symporter) 17 0 6 2 0 0 0 2 0 0 2 2 0 1 4 2 2 0 9 11 0 4 1 2 2 0 2 0 0 0 0 1 0 0 2 8 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09973() 3 6 13 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 2 4 0 4 5 1 6 1 0 0 0 2 0 0 0 0 20 2 14 2 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3341(Predicted double-stranded RNA/RNA-DNA hybrid binding protein) 1 0 1 2 3 1 1 3 0 4 4 5 2 3 4 2 5 5 1 1 5 1 0 1 1 4 0 0 0 0 0 2 3 4 6 11 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3487(Uncharacterized iron-regulated protein) 3 1 4 1 1 0 0 0 1 0 0 0 0 2 0 2 0 0 2 1 0 0 2 0 2 0 0 2 0 1 0 6 2 2 8 16 23 8 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3168(Tfp pilus assembly protein PilP) 25 5 1 0 0 0 0 0 1 0 7 1 2 2 1 1 0 0 4 0 0 0 1 0 0 3 0 0 1 0 0 0 0 0 0 0 15 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3390(Uncharacterized protein conserved in archaea) 0 0 5 0 0 0 0 0 1 0 0 1 0 4 0 0 0 0 1 4 5 3 12 2 1 0 3 4 1 1 4 8 3 3 0 8 2 0 3 4 2 2 0 0 2 0 0 0 0 0 0 0 0 0 0 3 NOG39260() 91 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3110(Uncharacterized protein conserved in bacteria) 88 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2882(Flagellar biosynthesis chaperone) 77 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 2 0 2 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14410() 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2388(Predicted acetyltransferase) 31 0 1 0 0 0 0 0 0 0 1 0 0 1 0 0 3 13 4 1 0 0 0 0 0 4 1 0 2 0 0 1 1 0 4 0 2 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13047() 49 0 0 1 0 0 0 0 2 0 1 1 0 1 0 2 5 10 3 0 0 0 1 0 0 2 1 0 0 0 0 0 0 0 0 5 3 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2097(Ribosomal protein L31E) 1 5 4 3 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 2 1 6 3 0 0 9 1 4 6 1 0 3 2 2 0 6 11 2 0 1 3 0 1 0 0 0 0 0 0 0 0 1 0 0 0 4 COG5314(Conjugal transfer/entry exclusion protein) 80 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG33051() 5 0 0 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 1 5 2 1 3 3 0 9 1 4 4 3 3 2 2 4 4 2 0 0 10 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 COG4279(Uncharacterized conserved protein) 8 1 1 1 2 1 0 0 0 0 0 0 0 2 0 0 0 0 1 0 3 0 0 0 0 12 4 0 0 4 0 8 1 1 2 1 0 28 7 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG06391() 1 1 3 2 15 0 3 4 0 0 9 0 1 6 0 1 0 3 4 0 0 0 0 0 1 1 2 2 1 4 0 4 3 0 2 5 2 0 0 3 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4933(Uncharacterized conserved protein) 8 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 1 3 1 2 1 0 0 0 4 4 2 0 0 3 8 4 2 14 2 0 3 4 5 2 0 0 0 0 0 0 0 0 0 2 0 0 0 10 NOG18965() 0 5 5 7 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 1 2 7 9 9 0 1 4 6 1 0 0 2 3 2 4 5 0 0 0 6 6 0 0 0 0 0 0 1 0 0 0 1 0 0 0 1 NOG18176() 42 12 1 1 1 0 0 5 1 3 0 1 0 6 0 0 0 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 13 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07948() 2 0 2 4 2 0 0 1 1 0 1 0 1 7 0 2 0 0 11 1 0 3 3 5 0 0 5 1 1 0 0 3 1 0 4 5 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3558(Uncharacterized protein conserved in bacteria) 53 4 0 1 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 0 3 1 1 2 1 0 1 1 2 0 0 0 2 0 0 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13980() 53 3 1 0 0 0 0 0 0 0 0 0 3 2 2 0 3 2 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14348() 2 2 7 3 0 0 0 3 1 0 0 0 0 3 4 2 2 2 0 2 2 6 4 4 3 7 0 0 1 0 2 1 3 0 10 1 0 9 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3360(Uncharacterized conserved protein) 68 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21202() 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 21 0 0 0 0 1 0 0 38 0 0 0 0 0 0 0 0 0 1 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG37591() 0 0 0 0 7 0 2 0 5 4 0 4 0 0 0 0 2 4 3 0 3 0 3 0 0 0 1 4 0 0 2 2 3 5 10 6 2 0 4 7 3 0 0 0 1 0 0 0 0 0 0 1 0 0 0 3 NOG14336() 1 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17709() 83 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18388(Acyl-Coa reductase) 7 1 6 6 0 0 3 7 0 0 0 0 0 2 0 2 0 0 0 1 1 3 0 1 1 2 0 0 2 1 2 5 2 0 6 15 2 0 3 4 1 2 0 0 0 2 0 0 0 0 0 0 0 0 0 1 COG3782(Uncharacterized protein conserved in bacteria) 2 0 0 0 0 0 1 0 0 0 0 0 2 2 0 0 0 0 0 0 3 1 0 0 0 1 5 0 1 0 0 0 0 0 0 0 7 63 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10613() 0 0 0 1 0 0 0 0 1 0 0 0 0 5 0 0 4 5 5 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3817(Predicted membrane protein) 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16339() 3 2 3 4 1 0 2 1 0 1 2 1 0 4 0 0 4 2 0 4 2 1 6 2 2 2 0 2 0 0 0 3 3 0 6 5 5 11 2 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG13249() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 14 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11479(Pfpi family protein) 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24239() 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 78 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19668() 2 1 0 2 1 1 1 2 3 0 0 0 0 6 0 1 0 0 5 3 0 0 2 0 0 0 2 2 1 0 0 4 2 7 7 8 2 12 5 6 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 NOG11188() 2 6 21 6 1 0 1 0 0 3 3 0 0 3 2 0 0 0 5 1 2 2 5 4 0 0 1 0 0 0 0 3 0 0 0 1 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG4714(Uncharacterized membrane-anchored protein conserved in bacteria) 65 1 0 1 0 0 0 2 0 0 0 0 2 0 0 1 5 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 1 2 2 6 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3762(Predicted membrane protein) 11 0 1 0 3 0 3 1 0 0 2 0 0 5 0 0 1 7 6 1 0 1 1 0 0 13 0 0 0 1 0 2 0 0 2 0 4 21 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG06212() 0 3 1 0 0 0 0 1 1 3 0 2 0 0 5 0 0 0 3 2 2 0 2 0 2 0 3 0 1 2 0 3 6 3 26 7 2 0 0 5 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4655(Predicted membrane protein) 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25905() 2 2 0 4 0 0 0 2 0 0 0 0 0 4 0 0 4 2 0 2 0 0 0 0 0 0 3 4 7 0 1 3 1 0 4 0 2 39 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19714() 3 0 0 0 1 0 0 0 0 0 3 0 0 10 0 0 0 2 2 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0 62 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG17303() 83 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20181() 0 0 2 0 0 2 0 0 0 0 0 2 3 4 0 0 0 0 2 2 0 1 1 1 0 0 4 10 1 0 3 4 3 3 8 9 0 13 3 2 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1 NOG27733() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 10 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG37109() 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21537(Cytochrome b6-f complex, subunit V) 3 6 5 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 9 3 11 10 8 0 1 2 5 2 5 3 0 0 0 0 0 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 NOG19751(Transcriptional regulator protein) 55 1 3 2 0 0 0 6 2 0 0 3 2 4 0 0 0 0 1 0 0 0 0 0 0 2 3 0 0 0 1 0 0 0 0 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35683() 1 4 19 4 1 2 1 1 0 0 0 0 0 0 2 2 2 0 0 1 3 5 4 1 4 0 0 3 1 0 0 8 2 0 7 2 3 1 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG10730() 8 2 0 1 2 1 2 0 0 3 0 0 0 0 0 0 0 0 0 0 5 0 0 1 0 0 0 0 0 1 0 7 1 0 2 0 0 34 18 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12880() 1 1 2 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 4 2 2 0 0 1 0 4 0 1 0 1 2 4 2 0 4 5 0 31 14 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19722() 0 1 3 1 0 0 0 0 1 0 1 0 4 3 0 1 0 1 3 3 2 0 1 0 0 0 3 6 1 0 2 3 1 5 9 8 0 2 8 2 3 6 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG23880(ABC transporter protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 7 8 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3418(Flagellar biosynthesis/type III secretory pathway chaperone) 80 5 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG37835() 1 2 2 2 0 0 1 4 1 4 0 0 2 0 2 0 0 0 0 4 0 1 0 0 0 1 0 0 2 0 0 4 12 4 21 5 2 0 8 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3554(Uncharacterized protein conserved in bacteria) 78 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10854(Circadian clock protein) 9 0 2 2 4 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 1 0 0 2 0 4 1 0 1 1 0 31 20 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG06465(Phosphatase) 73 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 8 2 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1634(Uncharacterized Rossmann fold enzyme) 1 3 10 5 0 0 0 0 1 0 0 0 0 0 4 1 0 0 0 0 1 3 6 0 2 6 2 5 1 0 0 3 8 1 0 10 0 0 7 4 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26650() 4 3 4 3 0 1 1 0 3 0 0 1 1 4 4 0 1 1 2 1 1 0 8 8 0 5 0 4 1 0 2 3 1 2 0 0 2 10 0 1 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 COG3489(Predicted periplasmic lipoprotein) 1 2 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 2 1 0 3 0 0 0 2 0 0 2 0 0 2 7 4 2 14 13 3 16 2 2 2 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG10803() 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11673() 88 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4171(ABC-type antimicrobial peptide transport system, permease component) 50 6 3 0 0 3 1 0 0 0 0 0 0 0 0 0 0 2 2 0 1 0 0 1 0 3 1 0 0 0 0 3 0 0 0 0 2 5 0 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12675() 0 0 2 3 1 0 1 2 1 0 0 0 0 0 0 0 0 0 2 4 2 1 1 1 0 44 0 0 1 1 1 1 2 0 0 2 3 11 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3048(D-serine dehydratase) 87 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4694(Uncharacterized protein conserved in bacteria) 77 1 2 0 0 0 0 0 0 0 0 0 0 4 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3805(Aromatic ring-cleaving dioxygenase) 53 0 2 4 1 0 1 0 0 0 0 1 0 3 0 0 0 4 2 0 0 0 2 2 0 1 1 0 1 0 2 2 0 2 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG32172() 48 0 1 2 2 0 0 1 3 0 0 1 0 0 0 0 0 0 0 2 3 4 3 0 0 3 1 1 0 0 2 1 0 0 2 2 0 1 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5473(Predicted integral membrane protein) 6 3 0 0 0 0 0 0 0 0 1 0 0 1 0 3 7 0 1 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 2 60 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3672(Predicted periplasmic protein) 38 8 0 0 0 1 0 0 0 0 2 0 0 0 0 0 3 0 0 0 0 0 1 0 0 10 2 0 1 0 0 0 0 1 0 2 7 11 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06353(Amidohydrolase) 2 1 2 5 0 2 0 11 3 3 0 0 0 15 0 2 1 0 7 0 0 1 3 1 0 0 0 2 2 0 1 1 2 3 6 5 0 1 1 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG38593() 2 1 2 5 1 1 1 0 1 0 0 0 0 1 0 0 2 0 0 1 2 0 0 0 0 0 0 0 1 0 0 1 2 2 0 2 2 51 2 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 3 NOG16864() 0 0 0 0 0 0 0 0 0 8 2 0 0 0 0 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 2 1 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06076() 86 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26729() 87 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04789(Nonspecific acid phosphatase) 29 1 0 1 1 0 0 0 0 0 0 1 0 0 2 1 0 0 0 0 0 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 48 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25557() 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5010(Flp pilus assembly protein TadD, contains TPR repeats) 62 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 0 0 1 0 0 1 0 0 0 1 0 0 0 2 0 0 3 12 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4225(Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins) 7 1 4 1 2 1 0 2 1 0 0 0 0 1 2 1 6 1 1 0 0 0 2 0 0 12 0 3 0 0 0 0 3 0 10 1 0 17 1 0 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG07955() 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06012() 1 3 4 1 0 1 2 0 5 0 0 1 0 0 0 3 2 2 3 0 0 0 0 1 2 5 4 1 3 0 0 0 4 0 0 6 1 26 4 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 COG5380(Lipase chaperone) 80 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17992() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 2 0 0 0 0 2 0 0 54 0 0 0 0 0 0 0 0 0 0 2 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13979() 42 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 2 0 0 0 0 0 3 2 10 1 1 1 0 0 1 2 8 4 5 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 1 COG3422(Uncharacterized conserved protein) 22 1 0 2 1 0 3 0 0 0 0 0 0 3 1 0 0 0 1 3 0 3 3 1 1 0 4 1 2 0 1 2 6 2 8 8 1 0 1 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5631(Predicted transcription regulator, contains HTH domain (MarR family)) 46 0 0 0 0 0 1 4 1 0 1 1 0 3 0 0 0 0 3 0 1 0 2 0 0 2 2 1 1 0 2 1 1 3 1 1 0 0 2 3 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 2 COG5523(Predicted integral membrane protein) 2 2 2 3 6 2 1 0 2 0 2 1 1 1 0 0 2 0 1 2 1 3 6 1 0 2 0 2 1 0 2 5 1 5 7 10 0 0 0 4 3 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG07946(NHL repeat protein) 3 8 15 3 0 0 1 2 2 0 0 0 0 2 0 1 0 0 7 0 2 4 4 0 0 0 1 0 2 0 1 1 2 1 1 7 2 7 0 5 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG16560() 3 2 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 2 7 4 14 10 4 0 2 4 8 4 12 0 2 1 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38209() 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07926(Phage major capsid protein, HK97) 2 0 0 0 0 0 1 0 1 4 1 0 0 9 0 4 2 0 15 2 0 1 7 2 0 7 0 0 1 0 1 1 3 0 0 0 0 19 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG12848() 54 0 0 0 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 2 1 2 4 0 1 0 1 3 0 0 0 0 0 0 0 0 6 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 COG1911(Ribosomal protein L30E) 0 2 7 1 0 1 0 0 0 0 0 0 0 1 0 0 2 0 0 1 3 4 5 3 3 0 7 1 2 0 0 1 5 1 0 10 7 0 2 8 5 2 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG13279() 87 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15437(Transposase) 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 7 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30167() 1 0 0 1 0 0 0 0 1 2 2 3 0 4 0 0 2 0 2 4 0 2 0 0 0 0 1 7 2 0 2 3 5 0 10 7 1 20 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG15557() 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22139() 7 6 7 3 0 0 1 1 0 0 0 0 0 1 0 1 2 2 1 5 3 1 7 1 0 8 0 0 0 1 6 1 3 1 8 7 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1656(Uncharacterized conserved protein) 66 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12518() 0 6 4 4 0 0 0 0 0 0 1 1 0 0 0 4 1 0 0 2 3 0 2 1 0 8 0 2 2 2 1 2 1 0 3 8 2 22 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG3379(Uncharacterized conserved protein) 0 1 1 0 0 0 0 0 2 0 0 0 0 3 0 0 0 1 5 2 0 0 0 1 0 1 0 0 1 0 0 1 0 2 4 0 12 47 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG28683() 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19748() 7 1 2 1 0 2 1 0 0 0 0 0 0 1 0 0 0 2 0 1 1 0 1 1 0 0 2 0 0 0 0 3 2 1 0 1 0 52 4 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09586() 84 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4628(Uncharacterized conserved protein) 32 4 0 1 0 0 0 7 5 3 5 4 1 3 0 0 5 3 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 11 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14170() 50 1 1 2 0 4 2 1 0 0 0 0 0 2 2 4 0 1 1 0 0 2 1 0 0 2 0 1 3 0 0 2 1 0 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18605() 45 0 0 3 1 1 0 0 0 0 0 0 0 2 0 0 1 2 0 4 2 0 3 2 3 0 0 0 1 0 2 0 0 0 4 3 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG4390(Uncharacterized protein conserved in bacteria) 47 3 6 6 0 0 0 5 0 0 0 1 0 0 0 0 4 2 0 2 0 0 2 4 0 3 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07924() 43 3 5 1 0 0 0 0 0 0 0 0 0 0 0 1 2 3 0 0 0 0 2 0 0 4 1 1 1 0 0 0 0 0 2 2 1 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12818(N-Acetylmuramoyl-L-Alanine amidase) 7 0 0 1 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 2 3 0 0 0 0 1 1 0 0 2 0 17 3 0 2 0 0 20 19 0 1 0 0 0 4 0 0 0 0 0 0 1 0 0 0 0 NOG13038() 0 3 16 4 0 1 0 0 1 0 4 1 2 0 0 0 0 0 2 1 5 1 2 1 1 13 0 2 0 0 2 5 1 2 6 3 1 3 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG13947() 0 0 1 0 3 0 3 3 0 1 5 3 2 5 2 3 0 2 7 1 2 0 1 0 1 0 1 2 1 0 0 2 3 2 9 2 0 5 3 6 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19964() 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17102() 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35772() 85 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21734(Acetyltransferase) 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5606(Uncharacterized conserved small protein) 71 0 0 0 0 0 0 0 0 0 3 0 0 4 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23853() 4 2 5 2 1 0 1 0 2 0 0 0 0 7 0 0 0 0 1 0 0 2 2 1 0 0 0 1 1 0 0 3 6 2 10 4 0 25 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18941() 61 1 4 3 0 1 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4794(Type III secretory pathway, component EscS) 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06018() 6 9 3 2 0 0 0 3 4 0 0 6 0 1 4 0 0 0 1 0 2 2 0 1 0 2 0 6 0 1 0 0 0 1 10 6 5 6 1 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3901(Regulator of nitric oxide reductase transcription) 12 6 3 5 0 0 0 2 2 0 1 2 0 3 2 1 0 2 1 6 0 4 6 0 1 0 2 4 1 0 1 3 0 0 0 6 5 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06241() 8 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0856(Orotate phosphoribosyltransferase homologs) 0 2 8 1 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 6 3 4 5 2 1 0 5 7 2 3 0 2 2 1 0 3 0 0 1 5 10 4 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG07854() 77 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3755(Uncharacterized protein conserved in bacteria) 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 2 0 0 0 0 0 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17195() 67 0 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 3 0 1 0 0 0 0 0 0 0 0 0 0 1 1 1 0 3 3 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18618() 3 12 10 3 0 1 3 0 0 0 0 0 0 0 2 0 0 0 0 2 4 1 1 1 0 0 0 1 2 0 1 2 2 9 8 16 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG28394() 0 0 0 0 0 0 0 0 0 4 2 1 0 0 0 0 0 2 0 2 0 4 0 2 0 1 0 4 0 1 2 16 6 1 9 4 2 6 2 6 4 2 0 0 1 0 0 0 0 2 0 1 0 0 0 0 NOG11774(Transcriptional regulator protein) 50 0 0 1 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG15100(Protocatechuate 4,5-dioxygenase) 4 0 3 1 0 2 2 4 1 0 7 0 4 5 2 0 2 5 3 3 2 1 2 3 0 2 4 2 2 0 1 1 2 1 4 3 3 0 2 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG16466(Acetyltransferase) 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 21 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2514(Predicted ring-cleavage extradiol dioxygenase) 44 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG07692() 9 0 1 0 2 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 1 0 8 1 2 0 0 0 36 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2933(Predicted SAM-dependent methyltransferase) 42 7 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 1 4 0 1 0 0 0 0 0 0 0 9 17 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10032() 7 6 3 5 1 0 1 3 1 0 0 0 1 2 2 2 0 3 0 1 1 1 2 0 5 8 5 5 1 0 0 1 2 0 2 6 0 3 0 2 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG07908() 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19004() 5 4 2 3 0 0 4 3 1 0 0 0 0 1 1 0 0 3 2 3 0 2 4 0 2 8 2 2 0 0 2 2 1 0 4 12 8 0 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1273(Uncharacterized conserved protein) 77 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 4 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11865() 37 3 3 3 0 2 1 0 0 0 0 0 0 0 0 0 0 3 0 4 0 4 4 2 2 0 0 1 2 0 4 1 0 0 5 2 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3607(Predicted lactoylglutathione lyase) 80 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11891(Pathway protein L) 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17871(HNH nucleases) 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 0 11 1 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14775() 0 1 3 3 0 0 0 0 1 1 1 0 1 2 0 0 0 0 2 6 0 0 1 1 0 0 0 0 4 0 2 7 3 5 18 7 0 9 2 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3594(Fucose 4-O-acetylase and related acetyltransferases) 5 1 1 1 1 0 0 0 0 0 8 3 4 0 0 1 9 6 6 0 0 2 0 0 0 12 0 1 3 0 0 0 2 2 6 3 0 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG18428() 1 5 4 3 1 1 3 0 0 0 1 0 0 5 0 0 0 1 0 2 0 2 3 5 1 2 5 4 0 1 2 4 2 0 10 5 0 9 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG4282(Protein involved in beta-1,3-glucan synthesis) 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12141() 9 7 11 6 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 4 0 2 1 3 8 0 0 7 0 0 0 0 0 7 10 5 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08477() 85 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3680(Uncharacterized protein conserved in bacteria) 3 10 6 6 0 0 0 0 2 1 1 0 0 0 2 2 6 1 1 3 1 0 3 2 3 2 0 6 0 0 0 3 4 0 9 1 0 1 0 2 0 1 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG19402(General secretion pathway protein) 85 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5343(Uncharacterized protein conserved in bacteria) 64 2 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 1 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36377(Transcriptional regulator protein) 83 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19099() 83 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19289() 0 3 5 3 0 0 0 0 0 1 2 0 0 1 4 1 2 0 1 2 0 4 0 0 2 6 3 5 1 0 0 1 3 2 2 4 0 24 0 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG14720(Transposase) 12 3 2 0 0 0 0 0 0 0 2 0 0 1 0 0 1 7 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 2 0 26 22 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG21813(Complete genome; segment protein) 0 1 0 0 0 2 0 11 1 0 2 2 7 0 0 0 0 0 1 2 3 2 23 8 6 0 4 4 2 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG09984() 46 0 2 2 0 0 0 0 2 3 0 0 1 0 2 1 5 3 0 0 0 1 0 0 0 5 0 0 0 0 0 1 0 2 0 0 0 7 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3190(Flagellar biogenesis protein) 68 4 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG37038() 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25967(Lipoprotein) 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21153() 2 0 3 1 1 1 2 0 0 0 0 0 0 0 0 1 6 4 2 2 2 0 0 1 6 6 2 1 2 0 0 0 2 3 5 7 0 21 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3896(Chloramphenicol 3-O-phosphotransferase) 70 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25507(Protein Rv2000) 2 3 4 1 2 0 1 0 0 2 3 4 3 0 0 1 1 0 3 3 3 1 5 1 1 0 9 0 1 0 0 0 1 4 5 3 0 4 0 6 2 5 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG25593() 1 1 22 3 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 4 3 5 1 0 1 10 4 0 0 2 2 1 2 2 11 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG04173(Lactotransferrin precursor (EC 3.4.21.-)) 0 0 1 0 0 0 0 0 3 0 0 0 0 13 2 0 0 0 0 3 6 7 4 2 5 0 0 5 1 1 4 8 7 0 0 4 0 0 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG22412() 2 3 3 2 0 0 2 0 0 2 0 0 0 0 0 0 2 5 0 0 2 2 2 4 4 3 2 3 3 1 0 0 4 0 7 11 0 10 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG24503(Fe-S oxidoreductase) 1 5 5 0 1 0 0 0 0 4 3 0 0 6 2 0 1 2 3 1 0 0 1 2 2 5 4 1 0 2 1 6 5 4 0 10 4 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG12917() 2 2 0 5 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 3 12 4 14 0 1 2 3 14 4 1 0 0 3 0 0 0 3 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 COG1433(Uncharacterized conserved protein) 1 3 13 2 0 0 0 4 0 0 0 0 0 2 2 0 0 2 0 0 0 0 1 0 0 16 0 0 0 0 0 0 0 0 0 0 17 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28812() 1 1 2 0 0 0 0 0 0 0 0 0 0 4 4 1 0 8 4 2 3 0 3 1 0 25 0 2 4 0 1 2 1 0 2 10 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG33891(Acetyltransferase) 85 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16807() 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15999(ATP synthase) 0 0 1 0 2 1 1 0 0 0 0 0 0 2 0 0 1 3 2 0 0 0 1 0 0 1 0 1 0 0 0 1 2 0 0 1 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1746(tRNA nucleotidyltransferase (CCA-adding enzyme)) 0 4 12 2 0 0 0 0 0 0 0 0 0 0 4 0 4 0 0 0 1 0 1 1 1 20 1 2 0 0 0 1 2 0 2 8 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14554() 1 0 10 4 0 0 0 0 0 0 0 1 2 5 0 4 0 0 1 5 0 0 2 0 0 0 0 0 0 0 0 0 0 0 2 3 5 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2310(Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1) 45 0 0 3 0 1 0 1 1 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 0 2 0 0 0 1 0 0 0 0 4 1 2 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18167() 52 1 1 2 0 0 1 3 0 0 0 0 7 0 2 3 0 0 2 2 0 0 1 0 2 0 0 0 1 0 0 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG06522(TM helix protein) 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16837(Dna-Binding protein) 79 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4127(Uncharacterized conserved protein) 0 0 7 1 0 0 0 0 0 0 3 0 1 4 0 0 3 0 1 0 0 0 0 0 0 5 4 2 0 1 0 2 2 2 0 0 2 42 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG5076(Transcription factor involved in chromatin remodeling, contains bromodomain) 0 4 8 4 7 15 0 2 0 1 0 0 2 0 2 1 0 0 6 1 4 2 2 0 2 0 0 0 0 16 0 1 0 0 0 1 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG5277(Actin and related proteins) 0 2 5 10 6 16 0 1 0 4 0 0 0 0 0 1 0 0 4 0 2 0 0 0 2 0 7 0 0 17 1 0 0 0 0 0 0 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3139(Uncharacterized protein conserved in bacteria) 21 3 0 0 2 0 0 2 0 1 3 1 2 2 2 1 1 3 1 2 0 0 0 1 1 0 6 0 0 1 0 1 0 0 2 1 15 9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11114() 5 8 8 15 0 0 0 1 0 0 2 1 0 1 2 1 0 0 1 2 1 2 4 2 3 0 6 0 2 1 0 3 1 0 0 7 1 1 2 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09045() 16 0 0 0 2 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 2 0 0 0 0 1 2 0 4 2 0 1 2 1 22 18 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG16066() 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1339(Transcriptional regulator of a riboflavin/FAD biosynthetic operon) 0 2 14 1 0 0 0 0 0 0 0 0 0 5 3 1 0 0 0 2 3 1 9 4 1 0 1 2 1 3 2 3 3 2 0 9 7 0 0 0 5 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4118(Antitoxin of toxin-antitoxin stability system) 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1967(Predicted membrane protein) 1 2 4 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 13 11 2 4 0 0 2 0 0 2 1 3 2 0 0 2 0 0 0 2 5 0 0 0 1 0 0 0 0 0 3 0 2 0 18 NOG17022(Protein, H-NS) 0 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 3 70 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3215(Tfp pilus assembly protein PilZ) 30 2 2 1 1 0 0 0 0 0 0 2 0 6 0 2 2 0 3 0 1 2 1 0 0 1 0 0 0 0 1 1 0 0 2 2 7 15 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25353() 1 2 2 4 0 0 0 0 0 0 0 0 0 22 27 0 2 4 0 4 0 1 0 7 0 0 2 0 0 0 4 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10075() 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15302() 4 8 4 8 0 0 0 4 1 0 0 1 3 2 0 3 0 0 1 0 3 2 4 2 0 0 0 2 2 0 1 3 1 2 0 11 4 6 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG1698(Uncharacterized protein conserved in archaea) 1 8 8 4 0 0 0 0 0 0 0 0 0 2 2 1 0 0 0 2 6 2 3 3 2 5 3 1 3 0 1 0 0 4 0 4 11 0 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG1685(Archaeal shikimate kinase) 0 2 7 2 0 0 0 0 0 3 0 0 0 0 0 0 0 0 1 8 5 0 7 3 0 7 3 1 0 0 0 2 3 6 0 7 0 0 3 6 5 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG36052() 0 1 0 1 0 0 0 8 0 0 9 0 0 0 0 0 0 0 1 0 0 0 4 0 0 0 3 0 0 0 0 0 0 0 0 2 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08017() 4 8 4 5 3 2 1 2 0 0 0 0 0 1 0 0 0 0 0 0 3 2 3 0 0 0 2 0 2 0 1 6 0 0 2 16 0 11 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1441(O-succinylbenzoate synthase) 36 3 3 1 0 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 2 2 6 2 0 0 4 2 0 0 0 1 0 0 0 4 2 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14963() 47 5 0 0 0 0 0 0 0 0 0 0 0 0 4 0 1 1 0 0 0 0 1 1 0 2 1 0 0 0 0 0 0 0 2 0 0 18 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4922(Uncharacterized protein conserved in bacteria) 62 0 0 1 0 0 1 0 0 0 0 0 0 0 4 1 0 2 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22200() 2 5 14 3 0 0 0 2 3 1 0 1 0 0 4 1 3 2 2 0 0 1 0 0 1 4 5 6 1 0 2 4 1 3 2 3 0 1 1 0 0 2 0 0 0 1 0 0 0 0 0 2 0 0 0 1 NOG18064() 0 2 3 1 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 4 11 9 1 2 0 3 1 2 3 1 4 7 0 0 4 0 0 4 5 1 2 0 0 0 0 0 0 0 0 0 4 0 0 0 6 NOG16933() 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2856(Predicted Zn peptidase) 29 1 0 1 0 0 0 0 0 0 0 0 0 0 2 0 1 6 0 0 0 0 1 0 0 1 0 2 0 0 0 0 0 0 0 0 4 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11670() 70 7 1 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09603(Methyltransferase) 0 7 3 1 3 1 1 2 1 1 2 0 1 5 0 0 2 2 1 0 2 2 1 1 3 0 0 0 0 0 0 3 1 0 8 4 11 10 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG1676(tRNA splicing endonuclease) 1 5 11 6 0 0 0 0 0 4 0 3 0 0 8 1 0 0 0 1 0 4 5 1 0 10 0 0 0 1 0 0 0 0 0 9 10 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG11238() 1 0 1 1 1 0 1 5 5 2 0 0 4 1 0 2 0 0 1 2 2 4 10 1 0 0 3 6 3 0 0 3 0 4 9 9 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5437(Predicted secreted protein) 2 0 0 0 0 1 0 6 0 0 3 0 2 0 2 0 0 0 5 0 0 0 0 1 0 0 3 0 1 3 1 1 3 0 0 0 2 42 0 2 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG22804(Response regulator receiver protein) 3 3 7 7 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 1 4 2 3 2 1 1 4 4 2 0 2 1 2 0 5 10 0 12 0 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG24144() 1 2 5 3 0 1 0 0 0 2 2 0 0 6 0 0 2 0 5 4 3 3 1 2 1 0 5 4 0 0 0 5 2 0 3 1 2 7 0 6 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11482() 53 0 4 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21058() 0 12 10 22 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 4 0 0 0 0 0 0 1 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3933(Transcriptional antiterminator) 13 0 2 3 0 0 0 0 0 0 0 2 2 1 0 0 0 0 0 3 0 4 2 2 1 0 0 2 1 1 2 0 2 2 9 10 0 4 6 6 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG16964() 1 2 1 1 0 0 1 5 1 0 3 0 1 2 0 1 0 0 3 1 4 0 0 0 1 0 2 0 0 0 0 5 3 3 13 5 1 10 4 3 0 3 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG09687(Protein involved in glycine, serine and threonine metabolism) 80 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1633(Uncharacterized conserved protein) 0 1 0 3 3 3 0 1 3 0 1 0 0 1 2 1 11 0 1 2 3 0 6 0 1 20 1 0 0 0 0 0 0 0 2 2 9 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06536(Transposase) 32 4 3 1 1 0 0 0 0 0 1 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 2 0 19 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11724(Histone H1 protein) 3 2 0 2 2 0 1 2 0 0 0 0 2 0 6 0 0 0 0 0 0 2 0 0 0 2 0 0 0 3 2 7 1 1 0 1 2 25 10 2 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 NOG06526(D--3-Hydroxybutyrate oligomer protein) 76 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36638() 82 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3109(Activator of osmoprotectant transporter ProP) 73 4 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4120(ABC-type uncharacterized transport system, permease component) 76 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21919(Phospholipase) 1 0 0 0 1 0 0 0 0 2 0 0 0 2 0 0 0 0 0 3 5 4 11 2 1 0 2 0 2 5 2 3 5 4 2 4 0 0 2 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 NOG15045() 3 3 1 3 0 2 1 1 0 1 0 4 4 12 2 0 4 3 3 1 0 0 2 1 1 2 1 1 2 1 3 1 0 0 2 6 0 7 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3434(Predicted signal transduction protein containing EAL and modified HD-GYP domains) 27 19 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 3 0 0 0 1 0 0 0 5 0 0 0 2 0 5 17 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14772() 0 0 0 2 0 0 0 2 2 0 5 0 1 2 2 3 0 2 1 1 0 0 0 1 0 0 2 0 0 0 0 5 4 8 4 5 0 10 7 6 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG24429() 4 0 6 2 1 1 2 5 0 0 0 0 0 3 0 0 0 0 1 4 4 2 3 3 0 3 0 2 1 2 3 3 4 3 0 5 2 7 0 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG08745() 76 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10805() 10 1 5 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 4 0 1 0 0 1 0 0 2 0 0 2 0 5 3 0 0 0 0 32 9 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG06514(Citrate utilization protein) 6 1 2 1 0 2 1 0 1 2 2 1 0 5 2 1 2 0 2 2 0 3 6 0 2 1 3 0 0 0 0 0 0 3 0 4 0 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4807(Uncharacterized protein conserved in bacteria) 31 2 0 0 0 0 0 5 8 4 2 0 3 6 1 3 2 0 4 0 0 0 0 1 0 0 3 0 0 0 0 1 0 0 0 4 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25673() 0 5 33 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 5 1 2 2 3 5 2 0 0 1 0 2 0 4 0 2 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG12589(Forkhead associated domain-containing protein) 1 0 2 3 0 0 0 0 0 0 0 0 0 0 0 2 3 5 3 2 0 0 0 2 0 1 0 0 0 0 0 0 0 1 0 4 0 51 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG3401(Fibronectin type 3 domain-containing protein) 0 2 5 3 1 0 0 0 0 0 0 0 0 4 0 0 1 2 0 0 0 1 0 0 0 0 6 0 2 0 0 0 0 0 1 0 10 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG39199() 3 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 1 6 2 9 10 6 0 2 0 6 8 10 7 1 0 4 1 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3111(Uncharacterized conserved protein) 56 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18449() 0 0 3 3 2 1 2 1 1 5 0 0 1 1 4 0 2 0 1 1 5 1 5 0 1 3 2 1 2 0 0 2 2 0 0 8 9 4 2 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG06345() 1 5 10 8 0 0 0 0 0 0 0 0 0 6 0 1 1 0 2 1 0 1 2 2 3 0 2 2 1 0 0 1 0 4 6 5 5 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG37107() 0 0 5 1 0 0 5 0 1 0 0 3 2 4 0 4 2 4 3 0 0 0 2 1 0 6 1 0 2 0 2 1 1 0 10 10 0 2 2 5 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3314(Uncharacterized protein conserved in bacteria) 44 3 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 1 0 2 0 0 0 0 0 0 0 0 25 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26308() 71 0 0 0 1 0 0 0 0 0 0 0 0 3 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09457() 1 2 5 4 1 0 0 0 0 0 2 1 0 6 0 0 0 0 4 0 1 0 6 0 0 0 0 0 0 0 0 0 0 0 2 2 7 29 2 2 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 1 COG4683(Uncharacterized protein conserved in bacteria) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 4 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2361(Uncharacterized conserved protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 1 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 11 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2382(Enterochelin esterase and related enzymes) 10 1 1 1 0 3 0 0 1 0 2 0 0 5 0 2 5 7 2 1 0 2 2 2 2 14 0 0 1 1 0 3 0 0 4 0 0 8 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14789(Major facilitator superfamily protein) 74 0 1 2 0 0 0 0 0 0 0 0 0 1 0 1 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4278(Uncharacterized conserved protein) 57 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 5 1 1 0 1 0 4 1 0 0 1 0 0 0 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG21031() 0 1 0 4 2 0 1 0 0 0 0 0 0 18 22 0 2 0 0 2 6 0 0 9 0 0 1 0 0 0 0 0 0 2 0 4 4 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07591() 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5449(Uncharacterized conserved protein) 4 0 0 0 0 0 1 0 0 0 1 0 0 10 2 0 2 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 3 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10042() 0 1 1 0 0 0 0 2 1 0 1 0 0 1 0 2 0 0 3 1 1 0 1 0 0 0 5 0 2 0 0 3 0 3 7 8 3 18 1 14 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG17465() 3 5 21 0 0 1 0 0 0 0 0 0 0 5 2 0 0 0 1 1 9 4 3 2 0 0 2 2 0 0 1 3 0 4 0 4 0 6 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG05995(Cyclic di-GMP binding protein) 70 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36759() 0 0 1 0 0 1 0 3 3 0 1 1 3 2 0 0 2 2 0 1 0 2 2 0 0 2 1 1 0 0 4 3 4 2 9 6 4 10 8 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3538(Uncharacterized conserved protein) 0 0 0 0 1 1 0 0 0 0 0 2 0 0 2 0 2 1 0 2 0 2 2 0 0 51 0 2 0 1 0 0 0 0 2 4 0 0 0 0 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14228() 68 0 1 0 0 0 0 4 0 0 2 0 0 4 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16723() 9 1 0 0 3 0 2 4 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 1 1 0 0 0 0 17 1 0 0 0 0 16 18 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09999() 47 3 0 1 0 3 0 3 1 2 0 0 0 1 0 0 0 0 3 0 0 2 1 0 1 0 0 0 0 0 0 1 2 0 0 1 0 6 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG16049(Cold shock protein) 0 0 2 2 0 0 4 0 4 0 4 1 0 0 2 1 0 2 0 2 1 2 3 3 1 0 0 3 2 0 2 5 5 2 13 7 1 0 0 3 0 3 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG36002() 78 0 1 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3708(Uncharacterized protein conserved in bacteria) 52 3 0 0 0 0 0 0 1 0 0 0 0 0 0 0 3 2 1 0 2 0 0 0 0 5 0 0 0 0 0 0 0 0 4 0 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23559() 1 2 4 4 0 0 1 0 0 0 0 0 0 0 0 0 0 5 0 1 4 4 5 2 2 3 1 1 0 0 4 4 1 8 4 2 3 7 0 4 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2977(Phosphopantetheinyl transferase component of siderophore synthetase) 7 4 8 3 0 0 0 1 7 8 0 0 0 1 0 2 0 2 0 0 0 3 5 3 0 0 2 1 4 0 0 1 2 0 2 4 3 4 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12975() 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 1 1 0 0 0 2 0 13 0 3 0 0 0 34 9 2 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG27847() 6 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 2 0 5 0 0 2 0 0 37 21 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36434() 74 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG11153() 46 5 2 0 0 0 0 0 0 0 0 2 0 1 1 0 0 0 4 0 2 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 5 9 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09661() 1 5 6 1 0 1 0 7 0 0 3 0 0 0 0 0 0 0 8 0 0 0 0 1 0 0 12 0 0 0 1 1 0 3 0 0 0 29 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16812() 0 2 4 2 0 0 0 2 1 0 0 3 2 9 2 2 0 0 2 3 1 0 3 0 2 1 3 0 1 1 0 2 0 0 5 4 3 14 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33647() 0 0 1 0 6 0 1 0 2 2 0 0 0 1 0 2 0 4 0 2 1 1 1 1 0 0 0 2 2 2 1 4 2 1 5 9 2 10 2 3 3 3 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG11899(Marr family protein) 80 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10837() 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 3 3 0 1 1 0 30 0 0 0 0 0 0 0 2 0 6 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG10142() 34 10 0 3 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 0 2 5 0 0 0 0 0 0 4 13 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19674() 0 1 2 1 0 0 0 4 0 0 3 0 0 1 0 0 0 0 1 2 0 1 1 0 2 0 3 1 0 0 0 9 4 4 10 7 0 9 2 6 0 3 1 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG22813() 0 0 4 5 0 0 0 2 0 0 0 0 0 1 2 0 0 1 0 0 0 2 3 0 2 0 4 4 0 0 8 0 3 4 12 4 0 16 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG05986() 3 3 15 7 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 2 8 3 0 8 3 6 0 1 4 0 2 0 0 3 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG24020(Gtra-Like protein) 75 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3295(Uncharacterized protein conserved in bacteria) 59 13 2 1 0 0 0 0 0 0 0 0 0 1 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11759() 3 4 3 9 0 0 1 4 1 0 0 0 0 0 0 0 2 0 1 1 1 3 6 0 1 0 6 2 0 1 0 1 4 2 2 7 0 10 0 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG15949() 0 0 1 1 0 0 0 0 0 0 0 3 0 2 0 0 0 0 2 2 4 5 0 0 0 6 1 0 1 0 0 2 0 0 0 3 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13325() 4 12 20 8 0 0 0 1 2 2 1 0 0 8 4 1 0 0 1 3 0 0 1 0 3 0 2 0 0 0 2 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG19095() 2 0 2 2 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 5 0 1 1 9 6 6 5 16 1 0 4 7 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11186() 1 1 1 0 0 1 1 0 2 0 0 0 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1 1 0 2 4 4 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG36093() 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 0 2 2 0 0 0 2 1 0 2 7 0 0 0 2 1 0 0 0 0 5 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38282() 0 0 1 0 0 0 0 1 2 3 4 0 0 3 0 2 0 3 0 3 0 1 3 1 0 2 3 2 0 0 0 7 2 2 18 5 0 0 0 8 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23636() 4 1 0 1 0 0 1 2 0 0 0 0 0 0 0 0 2 0 2 2 0 0 2 0 0 17 0 2 2 0 1 4 2 4 15 4 1 1 2 2 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 4 NOG19937() 81 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14951() 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08854() 3 1 1 2 0 0 1 0 1 0 2 0 2 0 0 2 0 0 5 1 2 0 0 0 0 3 3 5 2 0 2 2 0 0 2 6 6 20 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06114() 1 0 2 1 0 0 0 2 2 0 0 0 0 0 0 2 0 1 2 2 0 0 0 0 0 4 4 3 0 0 0 3 4 4 0 7 1 16 6 6 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG4693(Oxidoreductase (NAD-binding), involved in siderophore biosynthesis) 79 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14905(Dehydrogenase) 56 0 3 2 0 0 0 0 0 0 0 0 0 2 4 1 0 0 2 0 0 0 2 0 2 0 2 0 0 0 0 1 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2443(Preprotein translocase subunit Sss1) 0 1 5 0 0 0 0 0 0 0 0 2 0 2 0 0 0 0 0 4 3 6 5 2 0 0 1 4 3 1 2 5 3 9 0 4 0 0 2 3 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG17678(Surface protein) 0 3 4 5 5 5 0 6 0 0 2 0 3 3 0 0 4 3 7 0 2 0 2 0 2 0 0 0 1 3 4 2 0 1 2 7 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2445(Uncharacterized conserved protein) 9 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16671() 0 0 2 2 0 1 0 4 2 0 0 0 2 3 2 0 10 3 4 2 0 1 0 0 0 16 1 2 1 0 0 0 0 0 2 5 4 6 0 1 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG17399() 3 1 1 1 0 0 0 4 3 1 0 0 0 3 0 1 0 0 2 4 0 0 0 0 1 0 6 1 0 0 1 9 8 4 4 1 2 8 2 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3269(Predicted RNA-binding protein, contains TRAM domain) 0 0 7 2 0 4 0 0 0 0 0 0 0 2 0 1 2 0 0 4 0 3 4 0 1 9 1 0 1 0 0 2 2 0 0 5 8 0 2 6 4 0 0 0 0 0 0 0 0 0 0 3 0 0 0 7 NOG26470() 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11966(Helix_Turn_Helix multiple antibiotic resistance protein) 0 1 0 1 0 1 1 0 8 0 0 0 0 6 0 0 0 0 1 6 1 2 1 0 2 0 1 0 2 0 0 2 5 8 5 10 0 10 1 1 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG10031() 0 0 0 2 0 0 2 0 1 2 0 0 0 1 0 0 0 0 2 1 0 1 2 3 0 0 3 3 0 1 3 2 3 2 5 13 0 8 3 8 0 4 0 0 0 0 0 0 0 0 0 3 0 0 0 2 NOG25101(Adenine-Specific methylase) 1 3 1 3 0 2 2 0 1 0 2 3 0 1 0 0 0 2 1 0 2 0 1 2 0 7 0 0 1 0 2 2 1 2 6 4 11 10 6 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2842(Uncharacterized ATPase, putative transposase) 46 1 1 0 0 1 0 0 0 0 2 0 2 5 0 0 0 0 0 0 1 4 0 1 0 1 0 0 0 2 2 0 0 2 1 1 0 3 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 NOG14816() 49 1 0 4 0 0 0 1 0 4 0 0 0 2 0 0 0 0 3 0 0 2 2 1 2 0 1 0 0 0 2 2 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG19983() 42 6 0 2 0 0 0 4 0 0 0 1 2 0 2 0 0 2 4 0 1 1 0 1 0 0 1 0 1 0 0 0 1 0 2 0 2 4 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13305(Cytochrome c family protein) 0 3 0 3 0 0 0 1 0 0 0 1 0 2 0 0 0 0 0 0 0 0 1 0 2 2 0 2 0 0 0 0 0 0 0 0 2 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4307(Uncharacterized protein conserved in bacteria) 2 2 2 2 1 3 1 0 1 2 0 1 2 1 2 0 0 0 2 7 1 2 5 2 1 0 0 0 0 0 6 0 0 1 0 0 3 27 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33447() 0 0 5 3 1 0 2 0 0 0 1 3 0 2 0 0 0 0 2 3 3 6 2 0 2 8 1 5 1 0 0 2 0 1 6 8 2 4 0 0 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG34519() 1 2 0 4 0 1 0 0 0 0 0 0 0 0 0 1 2 2 1 2 4 3 7 6 0 23 2 0 1 3 5 1 0 0 0 2 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG06305() 28 1 1 5 0 0 0 1 0 0 0 0 0 0 0 0 0 2 1 0 0 1 4 0 1 0 3 0 3 2 0 5 1 2 2 0 2 12 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14725() 1 1 0 1 0 0 1 0 0 2 0 0 0 4 3 1 0 0 0 1 0 0 1 1 0 0 1 1 0 1 2 2 3 1 9 8 0 18 6 3 1 1 1 0 0 0 0 0 0 0 0 1 0 0 1 3 NOG26721() 1 0 1 1 4 0 2 0 10 0 3 5 4 0 0 1 0 0 0 0 0 0 3 1 4 1 0 4 2 0 4 3 0 2 12 2 0 0 0 0 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08654() 1 0 3 1 0 0 0 3 1 3 3 0 0 0 2 0 0 0 1 0 2 1 0 0 0 14 0 0 0 0 0 0 0 0 0 2 2 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5422(RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases) 0 3 4 2 4 6 0 0 0 0 0 0 0 2 0 0 0 0 1 0 2 3 3 0 0 0 2 0 1 12 0 4 2 2 0 11 2 1 2 2 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09497(Methyltransferase) 7 0 0 0 2 0 2 0 0 0 0 0 0 3 0 0 0 0 0 2 2 0 1 0 3 0 0 0 0 4 0 4 1 0 0 0 5 29 13 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG18846(17 kDa surface antigen protein) 2 7 11 4 2 1 1 0 0 0 0 1 0 2 0 0 0 0 0 0 2 3 5 2 1 0 1 3 2 1 1 3 1 2 10 6 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1148(Heterodisulfide reductase, subunit A and related polyferredoxins) 0 5 11 3 0 0 0 0 0 0 0 0 0 1 0 0 4 3 2 2 3 0 2 1 0 0 2 0 0 0 0 2 1 0 0 7 15 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08466() 16 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 3 0 5 0 0 0 1 0 27 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05965(Capsule biosynthesis protein) 0 3 25 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 5 9 4 3 1 0 7 1 0 0 2 0 2 0 3 0 3 0 0 1 2 0 0 0 2 0 0 0 0 0 3 0 0 0 0 COG2144(Selenophosphate synthetase-related proteins) 11 0 1 3 0 4 2 2 0 0 0 2 0 0 0 0 2 2 0 0 3 6 4 5 6 0 0 0 1 3 2 4 1 2 4 3 2 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10880() 1 0 1 1 0 5 0 2 0 0 2 0 3 2 2 0 2 2 6 2 0 0 2 1 0 12 5 0 2 0 0 7 1 2 2 5 0 6 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14473() 1 0 1 0 1 0 1 1 5 1 3 4 0 7 2 1 4 2 0 0 0 0 2 0 0 0 0 2 0 0 0 6 3 3 4 3 2 16 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG39162() 75 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10108(Lipoprotein) 78 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13370() 69 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14949() 0 0 2 0 0 0 0 1 0 2 0 0 0 7 2 2 0 0 2 0 1 1 1 1 0 2 5 4 0 0 1 3 1 2 5 4 4 14 2 5 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG1998(Ribosomal protein S27AE) 0 2 9 3 0 1 0 4 1 0 0 1 3 4 0 0 1 0 0 10 1 6 3 2 0 2 0 2 2 2 0 1 0 0 0 3 7 0 0 1 1 0 0 1 0 0 0 0 0 0 0 2 0 0 0 4 NOG09627() 53 0 0 0 0 0 0 3 0 0 3 0 0 2 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 2 0 0 0 0 0 4 8 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG36570() 2 1 0 1 0 0 1 5 4 3 1 4 0 3 4 3 9 1 2 2 0 0 2 2 0 1 0 0 0 0 0 6 1 0 8 5 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 COG4339(Uncharacterized protein conserved in bacteria) 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 2 2 0 3 5 0 1 0 2 0 0 0 0 0 5 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19786() 0 2 0 3 1 0 0 0 1 0 0 0 0 3 2 0 0 0 1 0 2 0 0 1 0 0 8 5 0 0 0 2 1 10 9 8 1 0 4 6 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG4083(Predicted membrane protein) 1 2 11 0 0 0 0 0 0 0 0 1 0 2 0 2 0 0 0 1 9 3 9 8 2 0 0 0 3 1 4 2 3 4 0 5 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG06108() 5 2 7 6 0 0 0 4 0 2 0 0 0 8 2 2 0 1 0 1 6 0 4 4 0 1 0 0 0 0 2 0 0 0 0 2 1 17 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG17279() 4 0 1 1 0 1 1 2 0 3 0 1 0 2 2 0 0 11 0 1 7 1 7 2 2 0 1 0 0 0 0 4 1 0 2 1 1 17 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG23331() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 14 0 0 0 0 0 0 0 48 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14563() 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10966() 0 2 1 0 0 8 1 1 1 0 3 0 0 6 0 0 0 4 4 2 0 5 1 1 2 9 0 0 1 2 0 0 0 0 0 2 0 20 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23382() 0 1 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 3 4 0 2 0 4 0 3 0 0 6 6 1 37 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11524() 47 1 5 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 0 0 2 1 0 0 1 0 0 2 4 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27560() 0 0 0 0 3 1 0 2 0 0 2 1 6 5 0 1 0 0 1 0 0 0 0 0 0 8 0 0 2 0 0 0 1 2 2 2 0 38 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06448() 60 0 0 0 0 0 0 2 0 0 2 0 0 2 0 0 2 0 1 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3513(Uncharacterized protein conserved in bacteria) 0 2 0 2 0 0 0 2 0 1 2 0 2 1 4 1 1 0 0 0 2 0 1 4 2 0 0 0 0 2 0 7 0 0 0 1 2 33 0 2 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG38374() 2 3 3 5 1 1 4 1 3 0 2 2 2 3 0 0 0 0 0 0 0 2 2 2 2 1 1 0 0 1 0 6 0 0 14 6 0 2 1 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20625() 0 4 13 5 1 1 0 0 0 0 0 1 0 2 0 0 0 0 0 2 2 6 9 0 0 0 0 3 3 1 0 3 0 0 0 6 4 0 0 4 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG11033() 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5268(Type IV secretory pathway, TrbD component) 74 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19663(Cyclic nucleotide-binding protein) 2 1 5 4 0 0 0 0 0 0 0 0 0 0 2 1 0 0 3 0 0 1 0 3 1 0 1 0 0 0 0 4 2 5 5 6 0 22 2 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2852(Uncharacterized protein conserved in bacteria) 6 0 0 0 0 0 0 0 0 0 0 0 0 7 1 0 9 0 0 0 0 0 0 0 1 2 2 0 1 0 0 0 0 0 0 0 17 31 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG09445(Phycocyanin beta protein) 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 2 0 0 0 0 0 55 10 1 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 NOG25823() 77 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06251() 14 0 1 1 0 1 2 0 0 0 1 0 0 4 3 2 5 9 4 3 0 2 2 2 0 7 0 0 0 0 2 0 0 0 2 3 2 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4633(Uncharacterized protein conserved in bacteria) 57 10 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12138() 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG39401() 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19018() 2 6 7 6 0 0 0 0 0 0 0 0 0 5 0 0 0 1 0 2 1 1 2 0 1 0 1 1 0 0 0 1 0 2 0 1 1 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08684(Curli production assembly/transport component) 64 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38250() 1 0 5 0 0 0 0 0 0 0 0 0 2 2 4 1 1 0 0 1 0 3 14 2 0 8 0 4 1 0 2 2 4 1 6 4 1 0 0 1 5 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19307() 0 3 23 6 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 2 0 8 3 1 4 0 6 2 1 0 0 0 2 2 2 3 4 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30931() 78 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4371(Predicted membrane protein) 6 0 1 1 1 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 2 0 8 1 2 0 0 0 25 21 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG18178() 1 1 0 0 14 1 2 4 0 4 0 0 0 2 0 0 0 0 0 0 0 5 3 0 3 1 0 0 1 0 0 2 3 0 8 11 2 0 0 4 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG18831() 74 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14480(Acetyltransferase) 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24082() 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4748(Uncharacterized conserved protein) 32 2 2 2 0 0 0 1 1 0 0 0 0 2 0 0 4 0 0 2 1 0 0 1 2 0 0 1 1 0 2 2 0 2 4 5 0 6 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12565(Chaperonin protein) 0 0 1 1 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 1 0 1 3 0 0 11 0 1 0 0 1 0 0 0 0 7 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19140(Biopolymer transport protein) 2 0 0 0 0 0 0 0 5 0 3 0 1 1 2 2 2 4 1 2 0 0 2 1 0 0 1 2 0 0 0 3 4 6 9 9 1 5 0 4 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG35066() 6 8 3 6 1 0 1 3 1 0 0 3 2 2 0 0 1 0 0 1 2 3 0 4 0 1 1 0 0 3 2 2 3 0 0 12 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07784() 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24147() 1 0 0 1 0 1 0 0 1 0 0 0 0 4 0 0 0 0 1 0 2 0 4 0 3 1 6 1 1 0 0 3 0 2 13 3 1 24 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10324() 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22437() 0 0 0 1 0 0 1 6 0 0 3 0 4 14 0 3 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 4 0 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4767(Glycopeptide antibiotics resistance protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 74 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04000(Alpha-Galactosidase) 0 3 3 6 12 12 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 1 0 0 0 2 2 0 0 18 1 0 0 0 0 2 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11806() 2 2 0 3 0 1 2 2 1 2 0 1 0 4 3 1 0 0 1 0 0 2 0 1 2 0 4 4 0 0 0 6 1 2 5 3 4 5 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 NOG14033() 73 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3725(Membrane protein required for beta-lactamase induction) 49 9 0 0 0 1 0 0 0 0 0 1 0 2 2 1 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18758() 0 1 0 1 0 0 0 6 0 0 0 0 0 7 0 0 1 0 1 2 1 1 0 2 0 1 4 1 0 1 0 8 3 6 12 4 2 2 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26543() 1 0 4 0 0 0 0 0 0 0 0 0 0 0 2 1 0 2 0 7 4 5 5 4 1 9 0 0 3 0 1 2 0 0 0 20 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06227(Lipopolysaccharide protein) 7 1 14 8 0 0 0 0 1 0 0 1 0 4 2 1 0 3 1 5 0 0 5 0 0 0 0 1 0 0 1 3 0 2 0 9 3 0 0 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG36401() 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21586(Transposase) 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13961(Accessory protein) 1 4 7 7 0 0 1 1 0 0 0 0 0 1 2 2 1 0 4 0 3 1 5 2 4 10 3 2 6 2 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 1 NOG15904() 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 5 3 0 0 1 0 0 1 0 0 0 0 0 0 1 0 0 0 1 1 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2516(Biotin synthase-related enzyme) 12 3 5 7 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 7 7 7 0 0 0 5 0 1 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07221() 1 2 0 2 0 0 0 0 0 0 0 0 2 25 33 0 0 0 0 0 3 0 0 4 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2829(Outer membrane phospholipase A) 39 10 3 0 0 0 0 0 0 0 3 0 0 0 0 1 2 0 0 0 0 0 4 0 1 0 1 0 0 0 0 2 0 0 0 0 8 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18942() 9 0 0 0 3 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 5 0 1 0 0 0 2 0 0 4 0 8 0 0 5 2 0 21 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG20184() 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 0 0 0 0 0 1 0 3 0 0 0 0 2 0 0 2 0 0 0 58 3 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 NOG06031() 8 5 1 0 1 0 1 0 0 0 5 0 0 0 0 0 0 0 0 1 3 2 1 3 2 2 1 7 1 3 0 1 1 4 0 0 10 0 7 2 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 1 NOG11073() 63 3 2 0 0 0 0 3 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4413(Urea transporter) 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5368(Uncharacterized protein conserved in bacteria) 3 0 0 1 4 4 0 0 0 1 0 0 0 2 0 0 0 2 1 1 0 0 1 0 0 1 3 0 2 0 2 3 2 4 12 4 3 4 2 7 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG11393(Gifsy-2 prophage protein) 28 0 0 1 1 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 0 3 2 2 4 0 1 0 3 1 1 0 1 0 4 0 0 13 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22519() 0 2 2 4 0 2 1 6 1 3 1 3 2 7 1 0 5 0 1 1 1 0 0 1 1 1 0 1 0 0 1 4 2 4 6 5 0 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13998() 0 7 0 2 0 0 0 0 0 2 1 0 0 2 2 2 2 0 5 2 0 0 1 0 0 3 7 0 0 1 1 1 2 0 0 0 2 17 0 8 1 3 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG24539(Histidine kinase) 55 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19697() 2 1 0 0 0 0 0 0 0 0 0 1 0 4 0 1 4 4 2 0 0 2 0 0 0 2 0 0 0 0 0 2 0 0 0 0 0 48 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14458(Thioesterase) 3 2 5 0 0 0 3 0 2 1 0 0 2 1 2 1 1 6 1 1 2 5 0 0 4 6 1 2 0 0 0 0 4 4 2 5 1 6 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG31586() 1 1 2 3 0 0 0 0 0 0 0 0 0 2 4 2 0 0 3 0 1 1 2 0 0 3 0 0 0 0 0 0 0 0 0 1 1 48 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG07980() 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 2 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17726() 3 0 0 1 0 3 0 4 0 0 1 1 0 5 0 1 2 8 1 0 0 2 1 0 0 11 3 0 0 0 0 0 1 2 2 5 0 12 0 2 0 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3915(Uncharacterized protein conserved in bacteria) 55 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19687() 1 0 2 0 0 0 2 2 0 0 0 0 0 0 0 0 2 0 1 0 1 4 2 1 2 0 2 0 0 0 0 9 3 6 2 9 3 12 0 5 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG18295() 1 2 1 1 0 1 0 0 0 0 2 0 0 1 0 1 0 1 3 0 2 0 1 0 6 2 2 4 1 0 2 0 3 2 8 4 0 20 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG23210() 43 0 0 2 0 1 0 0 0 0 1 0 3 0 0 0 2 1 0 0 0 1 0 0 0 4 5 2 1 0 0 1 1 0 4 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26995() 5 0 1 5 1 0 2 0 0 0 0 0 1 0 0 1 2 4 3 2 0 0 1 1 3 6 0 2 1 0 0 2 1 0 4 6 2 9 2 0 2 0 0 0 0 0 0 0 0 1 0 1 0 0 0 5 COG4113(Predicted nucleic acid-binding protein, contains PIN domain) 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 2 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38468() 5 2 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 2 4 2 10 4 0 4 0 0 2 6 4 0 6 0 0 2 4 1 5 0 2 0 0 2 0 0 0 0 0 0 0 0 0 NOG21360(Methyltransferase) 42 0 0 1 0 0 2 0 1 0 0 0 0 0 0 0 0 2 0 3 3 0 2 0 1 2 0 5 0 0 1 0 0 0 1 6 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22322() 0 0 0 0 0 0 1 6 0 1 8 0 0 5 12 1 0 1 11 1 0 0 0 1 1 0 4 2 1 0 0 6 9 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG5529(Pyocin large subunit) 1 2 2 1 0 0 1 12 2 1 1 7 0 3 0 1 6 3 2 0 0 3 0 2 0 2 1 1 2 3 1 1 2 2 0 1 0 7 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG22703() 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11810() 36 0 1 0 0 0 0 0 0 0 0 0 0 3 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 3 0 15 3 1 0 4 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06268(Dipeptidyl protein) 3 2 0 0 0 0 1 0 1 9 0 0 0 0 4 2 2 0 6 2 0 0 1 0 0 0 1 6 3 0 0 4 4 2 11 5 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4954(Uncharacterized protein conserved in bacteria) 45 0 1 0 1 0 0 0 0 0 0 0 0 2 1 0 0 0 0 1 0 0 5 0 0 0 0 0 1 0 0 0 1 3 4 5 2 0 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19709() 2 1 0 0 0 1 0 1 1 1 1 1 0 5 0 0 0 0 2 1 0 0 2 0 1 0 2 6 0 0 2 2 4 0 13 9 0 4 1 4 2 4 0 0 0 0 0 0 0 0 0 2 0 0 0 1 COG4565(Response regulator of citrate/malate metabolism) 10 3 7 2 0 0 0 0 0 0 0 2 0 0 2 0 0 0 1 4 0 2 5 2 2 0 3 3 2 0 0 0 0 0 0 2 15 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11792() 2 1 1 3 0 0 0 1 2 3 1 1 1 7 1 0 0 0 0 0 0 0 0 0 3 0 4 1 1 0 0 4 1 3 6 4 2 12 0 7 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG1299(Phosphotransferase system, fructose-specific IIC component) 35 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 4 2 1 0 2 1 0 2 1 6 4 4 1 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22095() 4 2 3 6 0 0 1 2 0 0 0 3 1 0 0 3 0 0 4 1 0 0 2 2 2 0 2 0 0 0 1 2 1 0 10 12 4 0 2 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15943() 1 0 1 0 0 0 1 2 1 0 3 6 4 4 0 1 2 4 2 2 0 3 0 0 0 18 1 0 0 0 0 2 6 2 0 0 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG18734() 6 1 0 1 0 0 1 3 4 0 0 2 0 3 2 3 2 2 2 0 0 0 0 0 0 5 0 0 1 0 0 9 3 0 10 4 2 0 0 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG26023() 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3916(N-acyl-L-homoserine lactone synthetase) 41 0 0 0 0 0 0 2 1 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 22 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13327() 59 0 1 0 0 0 0 0 0 0 0 0 0 3 0 2 4 3 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24460() 47 2 2 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 3 0 2 12 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17375() 0 3 3 1 0 0 0 0 0 0 1 1 2 4 0 0 1 0 0 4 1 1 1 0 0 0 0 2 0 0 0 3 4 5 11 5 1 11 1 2 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 3 NOG07838() 26 1 3 2 1 0 0 1 0 0 0 0 0 0 0 0 2 2 2 0 2 0 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21052() 0 1 1 6 2 0 0 0 0 0 0 0 0 17 23 0 2 1 0 0 0 0 0 12 0 1 1 0 0 0 0 1 0 2 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG27628() 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5427(Uncharacterized membrane protein) 0 8 24 2 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 2 3 3 5 2 1 0 0 2 2 0 0 0 0 0 0 13 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09341() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 6 5 0 0 0 0 0 0 21 0 0 0 0 0 0 2 2 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19299() 1 3 4 5 0 1 0 0 1 0 0 0 0 2 0 0 2 2 2 5 3 1 2 2 2 6 2 0 1 0 0 2 2 0 4 6 6 1 0 3 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 COG4312(Uncharacterized protein conserved in bacteria) 70 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18278() 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06304() 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5034(Chromatin remodeling protein, contains PhD zinc finger) 0 0 3 0 4 1 0 0 0 0 0 2 2 0 0 1 0 28 2 3 0 1 4 0 0 0 0 0 0 0 0 0 8 0 0 4 0 0 2 6 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26029(Protein involved in inflammatory response) 0 4 1 2 1 0 0 0 0 0 0 0 0 13 33 0 1 1 0 2 1 0 0 7 0 1 3 2 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17418() 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 3 2 0 0 0 7 2 0 2 0 0 2 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22209() 1 4 5 1 1 0 0 0 0 0 0 0 2 3 2 1 0 0 7 0 0 0 4 2 2 0 2 5 0 0 1 0 3 0 3 3 0 14 0 6 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4875(Uncharacterized protein conserved in bacteria with a cystatin-like fold) 2 4 7 7 1 0 1 4 1 2 1 1 4 2 0 0 0 0 2 1 1 0 2 2 2 1 3 2 0 0 1 4 1 4 2 1 3 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22138(Membrane serine protein) 6 2 0 6 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 9 12 4 9 0 0 5 1 3 7 2 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11892(General secretory pathway protein) 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16673() 3 0 4 3 0 0 0 3 0 0 0 0 6 4 0 2 2 0 3 3 0 0 0 0 0 9 2 0 0 0 0 0 1 2 6 7 2 10 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11047() 11 9 16 2 0 0 0 0 0 0 0 0 0 4 0 1 13 8 2 0 0 0 0 0 0 4 0 0 1 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21248() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 11 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1747(Uncharacterized N-terminal domain of the transcription elongation factor GreA) 1 1 1 1 1 1 0 2 0 2 2 1 2 6 0 1 6 0 0 0 3 0 0 2 1 8 2 0 0 0 0 3 2 2 0 3 3 16 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16636() 28 6 1 1 0 0 1 2 1 0 2 0 0 0 2 2 0 1 0 0 0 0 0 0 0 1 2 1 0 1 1 1 1 2 2 0 2 9 1 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 COG4759(Uncharacterized protein conserved in bacteria containing thioredoxin-like domain) 0 2 3 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 3 5 3 1 0 3 1 1 1 0 0 0 0 0 6 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07674(Proton extrusion protein) 3 0 1 3 0 1 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 2 0 1 0 0 3 12 2 2 0 2 0 21 11 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG23887() 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 60 4 2 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG4829(Muconolactone delta-isomerase) 48 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36361() 74 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25031(PAS domain-containing protein) 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23211() 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 8 2 0 1 0 0 0 0 0 17 0 0 1 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG23572() 68 1 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14495() 0 0 0 1 0 1 0 0 0 0 1 1 0 0 0 0 2 2 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27877() 2 1 6 5 0 3 1 2 0 0 0 0 0 7 2 4 1 2 0 3 0 0 4 2 2 0 1 0 1 0 2 4 2 0 10 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG18562(Histidine kinase-like ATPases) 70 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10076() 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5474(Uncharacterized conserved protein) 8 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 1 0 0 0 4 0 0 3 0 6 2 0 1 2 0 25 11 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 NOG12563() 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23067() 73 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3303(Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit) 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12937(Methyltransferase) 1 0 3 1 1 0 0 1 0 0 0 0 2 3 0 0 4 2 0 0 0 2 0 1 1 4 0 0 0 0 1 1 1 2 2 4 1 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32046() 5 0 0 0 2 1 0 0 0 2 0 0 0 0 0 0 0 0 1 1 1 0 1 0 0 0 1 0 0 1 0 12 2 4 0 1 0 26 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38047(Alpha/Beta protein) 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09656() 51 6 1 0 0 0 0 0 0 0 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16030() 2 4 2 3 0 0 1 0 0 0 2 0 0 0 2 2 2 0 2 0 0 0 9 2 3 0 1 0 0 0 0 3 7 2 4 2 3 13 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07964() 0 0 0 2 3 2 1 2 2 0 7 0 2 10 0 4 0 5 7 3 0 0 1 0 0 3 0 0 0 0 0 0 0 0 0 0 2 17 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17200() 50 11 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3439(Uncharacterized conserved protein) 2 3 13 1 1 1 0 0 0 0 0 0 0 1 0 2 0 2 0 2 0 0 3 5 2 2 1 0 0 0 3 1 0 2 0 0 4 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1755(Uncharacterized protein conserved in bacteria) 2 1 2 0 1 1 0 2 0 0 0 0 0 1 0 0 0 0 4 0 1 0 1 1 0 0 1 0 2 1 1 0 1 0 1 2 3 42 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25339() 0 1 0 0 0 0 2 3 2 0 2 2 2 0 0 0 1 2 0 1 1 0 1 1 4 13 2 0 3 6 0 1 1 3 3 3 0 0 7 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG15867(Transcriptional regulator protein) 0 0 0 2 0 0 2 3 1 2 0 0 3 4 0 0 0 0 2 1 0 0 1 1 0 9 3 0 0 1 1 0 0 2 0 0 0 33 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG14173() 1 2 4 5 0 0 0 2 1 0 4 0 0 1 0 0 0 2 0 4 0 1 0 5 2 0 3 3 1 0 1 1 3 0 6 9 1 2 8 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14584() 65 0 0 0 0 0 0 0 0 0 0 0 0 4 0 1 1 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13670() 0 0 3 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 1 2 5 8 12 1 0 4 1 2 0 4 3 7 0 0 1 0 0 3 2 5 0 0 0 0 0 0 0 0 0 0 1 0 1 0 5 COG5271(AAA ATPase containing von Willebrand factor type A (vWA) domain) 0 2 6 1 4 3 0 0 1 0 0 0 0 6 0 0 0 2 3 2 0 1 3 0 0 5 1 4 0 12 0 2 0 0 2 3 2 3 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG16713() 8 3 4 2 0 0 3 0 1 2 0 0 2 2 2 1 1 0 4 1 0 0 6 2 1 1 0 0 1 0 2 2 1 0 2 5 2 7 1 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14591() 55 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20746() 2 2 0 3 0 2 0 0 0 0 2 2 0 0 0 0 6 5 0 1 2 2 3 4 3 2 0 0 0 0 2 6 1 0 7 2 4 0 1 1 0 4 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG07603() 8 1 0 1 7 2 4 1 0 0 2 0 0 2 0 0 4 2 6 0 6 0 2 0 1 2 0 3 1 2 2 2 0 2 2 4 0 1 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23976() 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24868(Glycosyltransferase group 1) 73 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08476(Glycosyl transferase) 58 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 2 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2522(Predicted transcriptional regulator) 1 2 9 2 0 0 0 0 0 0 0 0 0 1 4 4 0 0 0 0 0 1 3 4 0 8 0 0 5 0 2 0 8 4 0 6 0 0 0 6 0 0 0 1 0 0 0 0 0 0 0 2 0 0 0 1 NOG06027() 68 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11625(Transcriptional regulator protein) 54 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 1 3 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 2 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12946() 47 1 6 3 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3945(Uncharacterized conserved protein) 26 6 4 8 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 2 1 0 1 0 0 3 0 0 0 0 0 0 0 0 0 8 3 7 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21157() 1 6 3 8 0 0 0 0 0 0 0 2 0 1 0 2 2 0 0 2 6 2 2 4 1 0 0 2 0 0 0 2 2 0 2 15 0 0 1 3 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13474() 3 2 1 0 0 2 1 1 1 0 0 1 0 1 2 4 2 0 2 0 0 1 0 1 2 0 0 4 0 0 2 1 2 1 10 0 2 19 1 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG5038(Ca2+-dependent lipid-binding protein, contains C2 domain) 0 2 12 8 8 11 0 0 0 0 0 0 2 0 0 0 0 0 7 0 4 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG32457() 0 0 0 0 0 0 0 0 1 0 4 3 0 6 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10073() 49 1 0 0 0 0 0 0 1 0 0 0 0 4 0 0 3 2 1 0 0 0 1 0 0 5 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18600() 66 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15049() 62 5 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14870() 34 13 11 4 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 3 0 0 0 0 0 2 0 0 1 0 1 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30836() 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21331() 0 1 0 0 1 0 0 0 1 0 0 1 2 0 2 2 0 1 0 1 0 0 1 0 2 0 4 2 2 0 0 5 9 4 0 10 1 0 7 2 4 2 0 0 0 0 0 0 0 0 0 4 0 0 0 2 NOG06512() 2 1 0 3 3 1 0 0 0 0 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33427() 70 0 1 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3528(Uncharacterized protein conserved in bacteria) 3 0 0 1 0 0 0 1 0 0 1 0 0 0 2 0 5 5 0 0 0 0 0 0 0 32 2 0 0 0 0 0 0 0 2 1 4 11 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15930() 33 0 1 0 0 0 0 3 1 0 1 4 3 2 5 1 0 2 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 12 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15770(50S ribosomal protein L32) 0 0 0 0 0 0 0 0 0 0 1 0 0 3 0 4 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4195(Phage-related replication protein) 0 1 6 2 0 0 0 0 0 0 0 0 0 1 0 0 7 6 2 1 2 2 7 0 5 18 2 0 2 0 0 0 0 2 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08087(Levansucrase) 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12966() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 69 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11425() 23 10 3 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 1 0 0 1 0 0 0 2 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG31698() 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15053(Protein traF) 51 4 1 2 0 0 0 0 0 0 0 0 0 1 0 2 0 2 0 0 1 0 1 1 0 2 0 0 0 0 0 1 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19411() 6 4 6 5 0 0 0 1 1 0 0 0 0 1 0 2 1 0 0 0 0 5 5 2 5 0 0 6 2 0 1 4 1 0 4 2 0 3 3 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06376() 62 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11662() 1 3 18 1 0 1 3 0 0 0 0 0 0 0 2 1 0 0 0 4 2 3 11 2 0 3 2 2 0 1 2 1 3 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 NOG05992() 35 3 1 0 0 0 0 0 0 0 6 0 0 0 0 3 0 1 0 0 0 0 1 0 0 0 3 0 0 0 2 0 0 0 0 0 4 12 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3081(Nucleoid-associated protein) 50 5 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 2 0 0 0 0 0 9 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12979() 16 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 2 0 0 0 1 0 1 0 2 2 0 4 0 2 5 0 0 23 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22961() 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11916() 53 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14081() 1 0 5 1 2 0 0 1 2 4 0 0 0 2 2 1 1 2 0 0 6 0 1 2 3 2 2 2 2 1 4 1 2 0 0 7 4 2 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG18309() 2 6 5 12 0 1 1 0 1 3 0 0 1 5 1 0 0 0 0 3 1 1 0 1 0 2 2 0 0 0 0 0 4 0 4 7 0 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21435(Glycosyl transferase) 2 8 8 3 0 0 0 0 0 0 0 0 0 0 0 0 7 6 0 3 0 2 0 0 0 5 0 0 0 0 2 0 0 0 2 3 7 12 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG34499() 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2093(DNA-directed RNA polymerase, subunit E) 1 4 7 2 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 4 4 10 2 2 2 2 0 0 1 1 1 3 1 2 0 5 2 0 0 4 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG32332() 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13481() 0 0 0 0 0 1 0 1 2 0 2 0 10 15 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 3 0 31 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19638() 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3586(Uncharacterized conserved protein) 1 2 5 0 0 0 2 0 0 0 1 0 0 0 4 0 1 1 0 0 0 1 1 0 2 1 4 1 0 1 0 3 1 0 2 4 2 29 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG17263() 62 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1326(Uncharacterized archaeal Zn-finger protein) 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 7 8 0 15 3 4 0 0 1 6 0 1 3 2 0 0 11 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 NOG26820() 15 2 0 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 7 0 0 0 0 0 0 0 0 6 0 15 1 4 2 0 0 2 10 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22850() 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG12954() 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 5 0 0 2 3 2 1 1 19 2 0 0 0 0 0 0 0 0 3 0 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13376() 0 8 23 5 0 0 0 0 0 0 0 0 0 1 0 0 3 0 0 2 2 3 5 0 3 1 3 0 0 0 0 4 1 0 3 3 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12639(Transcription regulator protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 19 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5411(Phosphatidylinositol 5-phosphate phosphatase) 0 3 1 0 7 7 0 0 29 0 0 0 4 0 0 0 0 0 2 0 0 3 0 0 0 0 0 0 1 6 0 1 0 0 2 1 0 1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18164(Tyrosinase) 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2602(Beta-lactamase class D) 35 0 1 0 0 0 0 0 0 0 2 0 0 4 0 0 0 0 0 0 3 0 2 0 0 2 0 0 0 0 0 1 0 0 0 1 8 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10305() 55 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23542() 0 1 26 6 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 5 2 3 0 0 1 4 0 0 6 6 0 0 0 3 2 0 0 0 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14485() 55 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4898(Uncharacterized protein conserved in bacteria) 0 0 1 1 2 0 0 0 0 0 0 0 0 2 1 5 6 4 2 1 1 5 3 3 0 15 0 0 1 0 1 0 0 0 0 2 5 5 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG17266() 33 1 1 1 1 0 0 0 0 0 0 0 0 3 0 1 8 2 2 0 2 0 0 1 2 0 0 3 2 0 0 0 2 0 4 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11275() 66 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16304() 0 1 2 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 1 0 3 0 0 0 3 0 0 3 1 2 3 0 0 46 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG29236() 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17208() 35 3 3 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 4 0 0 0 1 0 1 0 1 0 5 0 1 1 0 0 2 1 1 9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25560() 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3598(RecA-family ATPase) 0 0 0 1 1 1 0 2 0 1 0 0 0 6 0 2 2 0 5 1 3 0 2 0 0 2 1 0 1 1 0 0 8 0 2 3 4 22 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21737() 0 4 1 4 1 0 6 0 4 1 2 0 0 1 0 1 0 0 0 0 0 1 1 2 3 0 4 1 1 0 1 3 3 0 9 1 0 0 3 7 1 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 COG3949(Uncharacterized membrane protein) 1 1 14 10 0 0 0 0 0 0 2 0 0 1 0 0 0 0 3 0 3 9 0 0 0 0 1 1 1 0 1 1 0 3 4 5 0 5 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09827() 8 0 2 4 0 0 0 2 0 2 0 0 2 1 0 1 1 0 1 3 0 1 0 2 2 1 0 0 1 0 2 0 2 0 2 2 2 24 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 1 NOG04760() 0 1 3 0 0 0 0 0 0 0 0 0 4 4 0 0 2 0 0 0 0 1 4 0 4 1 2 0 0 0 4 1 1 0 0 3 0 32 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11987() 1 0 0 0 0 0 0 0 0 0 0 3 0 2 0 3 5 4 1 1 0 0 1 0 2 31 0 2 1 0 0 1 2 0 0 0 0 8 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16990() 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16477(O-Antigen biosynthesis protein) 4 2 3 0 5 0 0 2 1 2 0 0 0 0 0 0 3 2 3 0 0 0 3 0 0 1 0 0 1 0 2 1 0 0 2 7 8 17 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26588() 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33381() 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19154() 0 0 0 0 1 0 0 0 1 0 0 1 0 1 2 1 0 1 1 0 0 0 0 0 0 3 0 0 0 0 2 1 0 2 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06295() 6 0 2 1 3 1 0 0 4 2 0 0 0 4 4 1 0 0 2 0 0 0 0 1 0 4 0 0 0 0 0 2 0 0 2 0 2 28 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14639() 1 0 1 0 6 0 0 2 0 0 2 0 2 1 0 0 2 0 2 1 2 0 0 0 0 8 0 0 1 0 2 0 1 0 0 2 4 27 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 NOG08138() 70 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5573(Predicted nucleic-acid-binding protein, contains PIN domain) 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 3 1 0 0 1 1 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG21618() 0 2 10 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 6 2 8 4 4 0 4 4 3 0 0 0 2 1 0 0 0 11 6 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22167() 31 0 0 4 0 1 0 1 0 1 0 0 0 4 0 0 0 0 0 0 0 0 1 0 0 1 0 0 4 0 0 4 2 2 8 0 3 0 1 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08492() 6 1 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 2 0 4 2 2 0 2 0 27 16 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG39118() 0 4 8 4 1 3 0 0 0 0 0 0 0 0 2 0 0 4 3 1 0 0 1 0 0 5 0 0 2 12 0 0 0 0 2 4 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG35969() 0 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 3 2 0 0 0 2 5 0 2 0 0 0 0 0 0 1 2 0 2 3 0 41 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG11859() 0 3 2 2 0 0 9 0 1 2 0 0 0 2 0 1 8 12 2 0 0 0 0 2 0 3 0 2 0 0 1 4 1 0 8 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19839(HNH endonuclease) 1 1 0 1 0 0 0 2 1 1 0 0 0 2 2 1 0 2 0 0 6 0 0 0 2 9 1 1 0 0 0 2 0 0 4 6 0 20 1 2 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG36870(Protein involved in photosynthesis) 6 4 2 4 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 7 9 7 3 0 0 1 3 0 2 2 4 2 2 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3398(Uncharacterized protein conserved in archaea) 0 2 6 8 0 0 0 0 0 0 0 0 0 2 6 1 0 0 0 3 2 1 5 1 0 1 4 3 0 0 2 1 7 0 0 4 7 0 2 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG07875(Lipoprotein yceB) 61 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29609() 70 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30679() 0 1 1 1 1 1 1 0 0 0 0 0 3 2 2 0 0 0 0 2 0 0 3 0 0 3 2 8 0 2 0 7 3 4 14 1 0 0 1 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25794() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3405(Endoglucanase Y) 55 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 1 0 1 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19510() 69 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12961(Protein involved in metabolism of xenobiotics by cytochrome P450) 2 5 11 4 0 0 1 0 0 0 1 0 0 6 2 1 2 0 6 3 0 4 2 1 2 6 2 0 1 0 2 2 0 0 0 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14794(Protein Rv0007) 6 1 1 2 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 1 9 3 10 2 5 0 2 3 9 0 4 0 0 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 NOG14411(UPF0311 protein) 2 0 1 0 1 0 0 3 0 0 0 0 0 10 1 1 1 5 1 0 0 0 0 1 1 0 0 4 0 0 0 2 0 2 4 0 17 12 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG25608() 56 1 1 0 0 0 0 2 0 0 3 0 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11005() 4 0 2 0 0 3 0 2 2 0 1 0 0 2 8 1 4 3 0 5 0 0 1 1 2 0 2 3 3 0 3 0 1 6 2 0 0 6 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG23696() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 3 5 1 2 5 2 4 17 1 1 1 1 1 3 2 5 1 0 0 2 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 NOG17508() 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09426() 9 1 0 0 5 2 1 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 2 1 0 0 0 2 0 2 0 2 2 0 0 20 16 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12969() 7 0 0 3 3 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 3 1 1 1 1 0 0 4 0 4 2 0 0 0 0 26 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 NOG13334() 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11633(Membrane spanning protein) 0 0 6 0 0 3 0 0 0 0 0 0 0 4 0 0 1 0 2 0 3 0 1 3 0 0 0 0 0 0 0 1 0 0 0 0 0 42 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG2250(Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN) 0 2 4 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 1 0 0 4 1 0 0 2 1 0 0 0 0 0 5 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG39420() 4 2 1 8 0 0 0 0 1 2 0 0 0 0 2 0 0 0 0 0 0 2 3 1 2 0 0 0 2 0 0 1 3 0 4 6 0 16 1 2 1 4 0 0 0 0 0 2 0 0 0 0 0 0 0 0 NOG23311() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19185(Protein involved in indole and ipecac alkaloid biosynthesis) 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 2 0 0 0 0 5 3 4 2 7 3 32 2 4 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG3417(Collagen-binding surface adhesin SpaP (antigen I/II family)) 30 3 1 1 0 0 0 0 0 3 0 0 0 2 0 0 4 0 0 0 0 1 0 1 0 10 0 0 0 0 0 0 0 0 0 2 8 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG05994() 62 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11282(Transcriptional regulator protein) 43 4 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 2 5 1 1 0 0 0 0 0 0 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG20166() 68 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG0864(Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain) 1 10 9 5 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 1 0 9 0 0 0 0 0 1 0 0 0 4 5 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG23647() 69 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3445(Acid-induced glycyl radical enzyme) 61 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 4 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10080() 51 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 7 0 0 0 2 0 0 0 2 0 0 2 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23570() 1 4 24 4 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 3 6 3 6 1 0 0 0 4 1 1 2 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 NOG13381() 19 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 1 0 0 2 0 0 1 0 1 0 0 0 2 0 0 0 0 3 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04787() 0 0 0 0 0 0 0 0 0 0 1 0 1 8 0 0 8 5 0 1 0 0 0 0 0 29 0 0 0 0 0 0 0 0 1 2 2 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09446(Phycocyanin, alpha protein) 6 0 2 1 1 0 1 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 33 11 2 2 0 0 0 2 0 0 0 0 0 0 1 0 0 0 1 NOG17902(Two-Component system sensor protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19620() 2 0 0 1 0 0 0 0 0 4 2 0 1 6 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 49 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2845(Uncharacterized protein conserved in bacteria) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 2 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG11074(Chew-Like protein) 52 8 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 3 1 0 0 0 0 0 1 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4938(Uncharacterized conserved protein) 20 0 0 2 0 0 0 0 2 0 0 1 4 0 0 1 2 0 2 0 0 0 3 1 0 4 0 1 1 1 0 2 1 0 8 2 0 6 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG3459(Cellobiose phosphorylase) 14 0 0 0 0 1 0 0 0 6 0 0 0 1 0 0 3 3 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 13 22 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17427(Acid-Shock protein) 22 1 1 1 0 0 0 2 0 0 0 0 0 2 0 0 0 0 1 2 0 0 1 2 0 0 0 0 0 1 0 0 5 0 0 10 0 10 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 5 NOG13816() 0 0 0 0 0 0 0 0 0 1 0 0 0 4 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3014(Uncharacterized protein conserved in bacteria) 45 2 1 0 0 2 0 0 0 0 0 0 0 2 0 0 0 4 0 0 0 0 0 0 0 8 2 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10763() 1 0 2 0 0 0 0 2 8 0 0 0 0 0 0 0 1 2 4 0 0 0 0 0 0 27 0 1 0 2 0 1 0 0 0 0 3 13 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16460() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06442() 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 5 1 0 1 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG22923() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38112() 1 1 3 3 0 1 0 4 0 0 7 0 2 0 0 0 0 0 2 2 2 9 9 1 3 1 4 0 0 0 0 0 2 0 2 1 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 NOG11825() 2 0 0 0 0 1 0 0 0 0 5 0 0 4 2 3 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5305(Predicted membrane protein) 0 2 4 0 0 0 0 1 0 0 0 0 0 0 0 0 2 1 1 2 2 0 0 1 0 0 0 0 0 1 0 3 1 2 4 7 4 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33255() 11 0 1 3 4 0 0 1 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 1 0 1 4 2 2 1 0 2 0 0 18 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13818() 2 1 1 3 0 2 0 0 0 0 0 0 0 0 0 2 5 13 4 5 4 0 1 0 0 11 0 0 0 0 0 1 2 1 0 2 4 3 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG05990() 16 3 0 0 0 0 0 0 1 0 9 0 0 3 2 0 0 1 1 0 2 0 0 0 0 0 2 0 0 4 0 1 0 0 0 0 4 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13500(Acetyltransferase) 68 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19989() 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4792(Type III secretory pathway, component EscU) 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3557(Uncharacterized domain/protein associated with RNAses G and E) 1 2 3 3 0 0 0 0 1 0 0 1 2 0 2 1 2 3 0 2 1 5 5 4 2 3 3 2 0 0 2 1 1 0 0 6 6 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17201() 37 5 7 6 0 0 0 1 0 0 0 0 0 2 0 0 0 0 1 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG18065() 4 2 7 1 0 0 0 0 0 0 0 0 0 1 2 1 2 3 1 0 0 0 2 3 0 2 0 0 0 0 0 0 0 0 0 5 0 32 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14603() 4 7 14 12 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 11 0 0 0 0 0 0 0 0 0 5 4 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4383(Mu-like prophage protein gp29) 8 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 2 0 0 0 0 0 0 0 9 0 0 1 0 0 1 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 NOG33688() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG12665() 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3471(Predicted periplasmic/secreted protein) 62 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4111(Uncharacterized conserved protein) 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 2 0 0 0 0 0 0 1 0 4 2 0 2 0 0 0 4 0 0 2 2 34 4 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 4 NOG08802() 47 0 1 1 0 0 0 0 0 0 0 0 0 4 0 0 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 6 0 0 0 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16325() 7 0 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 1 0 0 0 3 0 5 0 2 0 0 0 30 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10842() 3 2 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 10 1 0 0 2 0 22 21 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19984() 52 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2 1 0 2 2 0 1 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20196() 5 2 2 4 3 2 1 0 1 0 0 0 0 0 0 1 2 2 0 0 2 2 3 3 6 5 1 0 3 1 1 2 1 0 5 5 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3530(Uncharacterized protein conserved in bacteria) 37 6 3 0 0 0 0 0 0 0 0 0 0 0 0 0 5 7 2 0 0 0 0 0 0 1 0 0 1 0 0 1 0 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1383(Ribosomal protein S17E) 0 0 4 0 1 1 0 0 0 0 0 0 0 1 2 1 0 0 0 0 0 4 3 1 0 5 1 7 3 0 0 2 4 2 0 5 11 0 0 1 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 5 COG4937(Predicted regulatory domain of prephenate dehydrogenase) 26 1 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2 2 1 2 0 13 0 2 1 0 1 1 0 0 1 2 0 5 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09423() 2 0 2 1 1 0 0 0 0 0 2 2 0 1 2 1 0 0 3 0 0 1 0 0 0 5 0 0 1 0 0 1 1 2 0 8 7 22 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG14122(Phage shock protein) 33 1 1 0 0 0 1 6 1 1 1 0 0 0 0 0 0 0 1 2 0 1 4 0 2 0 0 0 1 1 0 2 2 0 0 3 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27986() 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4752(Uncharacterized protein conserved in bacteria) 4 2 4 5 1 1 0 0 0 0 0 0 0 2 0 0 2 2 0 0 2 2 7 3 9 0 1 0 5 3 0 1 1 0 0 0 2 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3889(Predicted solute binding protein) 2 7 9 6 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 2 0 0 20 0 0 0 0 0 0 0 0 0 8 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09338() 2 3 3 3 4 1 0 1 0 0 0 0 1 0 0 0 0 0 3 0 0 0 3 2 0 5 2 1 1 0 2 0 1 0 0 4 0 17 0 2 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 5 NOG33211() 3 0 0 1 0 0 0 1 0 0 0 0 1 0 0 0 0 0 1 2 0 0 0 1 0 0 0 0 0 3 0 6 0 0 0 0 0 40 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08378() 4 0 1 3 0 1 0 0 0 1 0 1 4 1 0 0 0 0 3 0 3 4 0 0 2 4 0 1 0 0 0 3 1 0 0 4 0 20 2 1 1 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG08834() 0 0 2 1 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 2 0 0 0 0 3 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 COG3045(Uncharacterized protein conserved in bacteria) 53 3 0 2 0 0 0 0 0 0 0 1 0 0 0 1 0 2 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14169() 18 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 4 0 0 18 2 0 0 0 0 3 3 0 0 0 2 9 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 NOG08761(DNA ligase III) 46 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 1 0 2 1 0 0 1 0 0 0 0 0 0 0 0 1 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09953() 2 1 5 3 1 0 1 2 5 0 1 0 1 1 0 1 0 8 3 4 0 0 0 0 0 6 0 0 0 0 0 2 0 0 6 3 2 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08917() 0 0 0 0 0 0 0 5 1 2 1 2 2 7 0 0 1 0 1 0 0 0 1 0 0 1 0 0 0 0 0 1 1 0 0 0 0 41 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5347(GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport) 0 1 11 1 4 9 0 1 0 4 0 0 0 0 0 0 0 0 4 4 4 1 0 0 7 0 0 0 1 9 0 0 0 0 0 1 2 2 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG04026(Oxygenase subunit) 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17068() 1 3 2 3 0 0 0 0 0 2 0 0 0 5 0 1 9 1 1 1 0 3 0 2 0 8 1 0 0 0 0 0 1 0 0 2 13 6 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25531() 66 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06503(UPF0089 protein Rv3234c) 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 2 59 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG12545() 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 2 2 2 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26178() 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1872(Uncharacterized conserved protein) 27 0 1 0 0 0 0 0 0 0 0 0 0 5 4 0 3 4 2 1 0 0 0 0 0 2 4 0 1 0 3 1 0 2 0 1 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG16917() 48 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG3647(Predicted membrane protein) 33 1 0 0 0 2 1 2 0 0 1 0 0 0 0 0 5 2 1 0 0 0 0 0 0 6 2 0 0 0 1 3 3 0 0 0 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36476() 0 0 2 4 0 0 1 0 2 6 5 4 0 3 0 0 0 3 4 1 3 0 0 1 1 0 0 2 1 1 0 0 6 2 4 4 0 6 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09705() 0 4 17 3 3 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 1 0 4 5 0 3 1 2 0 2 2 5 0 2 0 0 0 8 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG11450() 0 2 0 0 0 0 1 1 1 0 1 1 0 3 2 2 10 12 1 0 0 2 1 0 1 0 2 3 1 0 0 1 0 1 4 2 7 5 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21635() 1 3 9 6 1 1 0 0 0 0 0 0 0 2 0 1 0 0 0 1 2 0 1 2 2 3 0 0 1 2 0 6 1 0 6 1 0 0 9 4 0 0 0 0 1 0 0 0 0 0 0 1 0 1 0 0 COG3714(Predicted membrane protein) 43 0 0 0 0 0 0 0 0 2 1 0 0 2 2 0 0 0 1 0 0 0 0 1 0 3 0 0 0 1 0 0 0 0 0 3 2 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1675(Transcription initiation factor IIE, alpha subunit) 1 2 8 7 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 9 5 0 0 1 0 0 0 0 0 5 23 3 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21320(Transcriptional regulator protein) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25197(Amidohydrolase) 5 1 2 0 0 0 0 0 0 0 2 0 0 5 0 2 0 0 4 4 3 3 5 0 4 2 0 0 1 0 0 2 1 2 5 11 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13936() 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23861() 11 17 4 9 1 0 1 0 0 0 0 2 3 0 0 0 0 1 0 1 0 0 4 1 0 0 0 0 0 0 0 0 0 0 2 5 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG10082() 13 1 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 2 0 2 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 35 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG13987() 0 1 1 3 1 2 0 0 0 0 0 0 0 1 0 0 2 0 1 0 0 0 0 0 0 46 0 2 0 2 0 0 0 0 0 2 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08916() 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36271(Regulator protein) 48 0 0 2 1 0 0 0 1 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 5 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2965(Primosomal replication protein N) 47 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 3 8 1 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14143() 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 2 3 5 0 3 0 4 5 4 0 0 0 0 2 3 4 14 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 9 NOG09727() 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06274() 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17043() 44 0 0 0 0 0 1 0 0 0 0 0 0 0 4 0 5 3 0 0 0 0 0 0 0 6 0 0 0 0 2 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1742(Uncharacterized conserved protein) 49 4 0 0 0 2 0 0 0 0 2 0 0 1 2 0 3 0 0 0 0 0 1 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG38408() 58 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1941(Coenzyme F420-reducing hydrogenase, gamma subunit) 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 9 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11929() 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3884(Acyl-ACP thioesterase) 0 0 3 0 0 0 1 0 0 0 0 0 0 0 0 0 2 16 0 0 0 0 0 1 0 40 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18602(Lysine-N-Methylase) 49 0 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 4 0 1 0 0 0 0 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11694() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 3 5 1 2 2 0 0 0 0 9 2 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19122() 1 2 0 0 2 1 4 1 2 2 2 0 0 2 0 3 0 1 1 0 2 0 0 1 2 1 2 1 2 0 0 3 3 3 2 6 5 5 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16190() 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 4 4 2 0 0 0 0 0 0 3 0 0 0 1 0 0 0 0 0 0 0 48 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33173() 5 0 0 0 0 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 3 0 3 0 20 4 2 2 1 0 10 9 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5615(Predicted integral membrane protein) 43 7 5 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36132() 66 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27300() 0 0 0 0 0 0 0 4 0 0 0 1 0 0 0 0 0 4 3 1 2 0 0 0 0 20 0 0 0 0 0 0 0 0 0 3 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG35986() 1 0 4 0 5 1 0 2 1 0 1 1 0 0 0 0 0 1 0 0 0 0 0 0 2 1 0 0 0 0 0 6 2 2 0 0 0 30 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14601() 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1945(Uncharacterized conserved protein) 1 4 9 8 0 0 0 0 0 0 0 0 0 1 2 0 0 1 0 0 1 1 0 0 2 14 0 0 1 0 0 1 0 0 0 5 6 8 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11082() 49 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20752() 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06516() 13 0 2 0 2 2 2 4 0 1 1 1 0 4 0 0 1 2 0 0 0 1 0 1 3 5 4 0 1 0 2 0 4 2 0 3 0 2 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11894(Dehydrogenase) 41 0 6 1 0 0 1 0 1 0 0 0 0 0 0 1 0 0 1 2 0 1 0 1 1 0 0 0 0 1 0 0 1 0 2 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG22921() 0 0 1 1 1 0 1 2 1 0 0 0 0 0 0 2 2 0 0 0 0 0 1 0 0 8 0 0 2 0 0 3 2 0 4 0 9 17 0 5 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3493(Na+/citrate symporter) 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08752() 65 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09843(Minor curlin subunit) 63 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09319() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 6 0 0 0 0 0 1 0 38 0 0 0 0 0 1 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1308(Transcription factor homologous to NACalpha-BTF3) 1 4 5 3 1 3 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 2 7 0 2 11 0 1 0 3 0 2 0 0 0 4 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09599() 66 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08022(Glutathione protein) 56 0 0 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07843() 0 0 1 1 2 0 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 7 5 3 3 0 0 1 2 0 0 3 0 1 22 0 2 4 0 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13985() 66 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4456(Virulence-associated protein and related proteins) 47 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 3 0 0 0 0 0 0 0 0 2 0 4 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG37500() 62 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07951(Transcriptional protein) 9 0 0 0 1 1 0 2 0 2 0 0 0 7 0 2 0 2 1 1 0 0 0 0 0 4 3 0 2 0 0 4 5 0 2 2 2 13 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5028(Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3) 2 7 3 10 2 2 0 8 0 2 0 0 0 0 4 0 0 0 2 0 0 1 4 0 0 0 0 0 1 5 0 3 0 2 0 0 0 7 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38995() 0 3 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 4 49 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG17269() 46 7 1 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 1 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36059() 37 5 1 3 0 0 0 0 0 0 6 0 0 6 0 1 2 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4264(Siderophore synthetase component) 60 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG39422() 6 0 6 5 2 1 1 1 0 0 2 0 0 0 0 2 2 0 2 0 4 3 14 4 0 6 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2704(Anaerobic C4-dicarboxylate transporter) 62 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23828() 1 0 0 2 0 1 1 1 2 0 4 0 2 6 0 1 1 0 2 2 1 0 3 1 0 0 0 0 1 0 0 3 0 3 8 6 0 3 1 7 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 NOG23399() 2 1 3 2 0 0 0 0 3 2 0 0 0 2 0 0 2 6 2 0 0 0 0 1 1 0 0 6 0 1 0 3 0 3 2 6 1 8 1 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 COG4950(Uncharacterized protein conserved in bacteria) 54 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22890() 64 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2162(Arylamine N-acetyltransferase) 60 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3068(Uncharacterized protein conserved in bacteria) 37 6 3 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 13 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07962(Type II restriction protein) 3 0 1 1 0 2 1 0 0 0 0 1 0 0 2 0 2 3 1 0 0 1 1 1 5 5 0 0 0 1 0 2 1 0 4 4 1 15 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 4 NOG19284() 2 0 0 1 1 2 0 3 1 4 0 0 0 2 0 1 0 2 5 0 0 0 0 0 6 0 2 0 2 0 0 4 3 2 8 2 3 5 0 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08609() 44 4 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22046() 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09622() 6 7 5 0 0 4 1 0 0 1 4 0 0 6 0 0 0 0 4 0 0 3 5 0 2 0 0 1 2 0 0 1 0 3 4 0 2 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04712() 9 2 0 0 3 0 1 0 0 0 0 0 3 0 0 0 0 0 0 0 3 0 1 2 0 2 0 1 0 1 0 5 1 0 0 2 0 10 16 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27424() 60 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28014(Possible protein phosphatase 2C) 7 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 0 0 0 0 4 1 0 1 0 5 2 0 0 0 0 18 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 COG3043(Nitrate reductase cytochrome c-type subunit) 58 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21660() 9 0 0 3 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 1 0 0 0 0 3 2 1 0 3 2 0 0 0 0 17 15 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06760() 0 3 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 3 4 0 7 2 1 25 1 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13606(Chromosomal protein) 0 2 3 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 2 0 6 2 3 6 0 2 2 2 1 1 3 4 0 0 3 0 0 2 3 5 9 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13552() 3 0 0 0 0 2 2 4 2 1 3 2 0 7 1 2 6 0 4 0 0 1 0 1 0 0 1 0 0 1 0 2 1 0 0 1 0 0 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 14 COG3457(Predicted amino acid racemase) 4 0 0 0 0 0 0 1 2 5 4 5 0 14 4 2 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12956() 9 0 0 3 2 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 0 0 1 0 1 0 3 1 8 0 0 0 0 0 12 16 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16604() 61 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16714() 0 2 20 4 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 5 0 1 4 1 1 4 0 0 1 0 0 1 2 0 4 0 1 8 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21235() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 6 17 2 0 0 0 0 1 0 31 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15836() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 7 13 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29810() 64 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5260(DNA polymerase sigma) 0 1 1 0 3 4 0 1 0 4 0 0 0 0 0 1 0 0 1 0 2 2 4 2 2 0 2 0 0 5 0 8 7 0 0 0 0 0 3 4 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 COG5215(Karyopherin (importin) beta) 0 0 12 3 4 4 0 0 0 6 0 0 0 4 0 0 0 0 13 3 4 0 1 0 0 0 1 2 0 3 0 0 0 0 4 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19049() 1 0 0 0 0 0 0 1 0 0 0 0 0 3 0 0 0 0 3 0 2 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 4 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30799() 1 5 2 1 1 0 0 0 0 0 0 0 2 14 24 0 2 0 0 2 0 0 0 6 0 1 0 0 0 0 1 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14227() 16 0 0 0 0 1 0 0 0 0 0 0 0 2 0 0 4 1 1 0 0 0 2 0 0 1 0 0 1 0 0 0 0 0 1 4 2 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13581() 0 0 2 2 0 0 0 0 0 0 0 1 0 4 0 3 0 0 0 0 0 5 5 2 2 0 1 0 1 0 0 3 8 2 2 5 0 0 2 4 1 5 0 0 0 0 0 0 0 0 0 2 0 0 0 3 COG4802(Ferredoxin-thioredoxin reductase, catalytic subunit) 4 1 1 0 1 0 1 2 0 0 0 0 0 1 0 0 0 0 1 1 4 1 1 2 0 0 0 0 0 1 1 4 1 2 0 0 2 19 10 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG04902(Dnase gamma (Deoxyribonuclease I-like 3)) 0 0 0 3 0 0 0 0 0 0 0 0 0 3 0 1 0 0 0 1 2 0 0 0 2 0 1 2 0 0 0 0 2 0 0 3 2 18 3 10 6 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08820() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 5 4 0 3 1 3 5 1 0 0 4 5 0 0 3 2 0 2 6 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 11 NOG36290() 57 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07627() 0 1 3 0 0 2 0 0 0 0 0 0 0 2 0 0 0 0 0 10 2 3 7 0 0 0 2 0 0 2 2 5 5 2 0 2 2 0 0 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 NOG06147() 51 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3897(Predicted methyltransferase) 5 2 2 0 1 1 0 1 0 0 3 1 0 2 0 0 0 0 3 6 0 0 2 0 2 0 0 1 0 0 0 0 0 0 0 2 0 25 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3382(Uncharacterized conserved protein) 3 2 4 2 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 2 0 1 0 0 3 0 3 2 0 0 0 0 0 0 0 0 4 32 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 COG4399(Uncharacterized protein conserved in bacteria) 0 17 7 0 1 3 0 0 2 0 4 0 0 1 0 5 0 0 0 0 0 4 0 0 0 1 0 4 0 2 0 1 3 0 0 1 5 3 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18311() 0 10 15 6 1 1 0 0 4 0 0 0 0 1 0 0 1 0 1 0 1 0 1 0 0 0 0 2 0 0 0 1 2 2 8 4 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2985(Predicted permease) 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 2 0 1 0 0 0 0 0 0 5 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG31514() 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 1 0 1 1 0 10 3 0 0 0 0 25 17 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG05648(DNA (cytosine-5)-methyltransferase) 0 0 1 2 1 0 0 6 1 2 6 0 0 2 4 0 2 2 2 0 2 0 1 2 2 4 0 2 1 3 0 3 2 2 2 2 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG06120() 61 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 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1 0 2 0 6 1 0 0 0 0 11 8 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3105(Uncharacterized protein conserved in bacteria) 8 0 3 1 0 0 0 2 0 8 4 0 1 0 0 2 1 0 3 0 1 3 0 0 0 0 1 0 3 0 0 1 0 0 0 0 10 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG38030(Streptothricin acetyltransferase) 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14218() 54 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28162() 62 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10783() 9 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 3 0 3 1 4 0 0 0 25 11 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19567() 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10071() 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4117(Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)) 50 1 1 1 0 0 0 0 0 0 0 1 0 0 0 0 3 2 0 0 0 0 0 0 0 2 0 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09858(Esterase/Lipase) 51 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 2 2 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14838() 45 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 3 7 0 0 0 0 0 0 0 5 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5280(Phage-related minor tail protein) 0 1 1 2 0 0 0 0 0 0 0 0 0 2 0 2 0 0 4 0 0 0 2 4 0 0 3 0 0 2 2 0 2 0 4 0 4 27 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11911() 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG27983() 63 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2425(Uncharacterized protein containing a von Willebrand factor type A (vWA) domain) 24 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 2 0 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COG4405(Uncharacterized protein conserved in bacteria) 0 2 10 5 0 0 1 0 1 2 0 0 2 2 0 2 4 2 1 0 2 0 0 0 0 7 0 0 0 0 0 0 1 0 2 0 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16717() 37 4 1 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 1 0 1 1 3 0 1 0 0 0 0 0 0 0 4 5 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19557(Nucleotidyltransferase substrate-binding) 8 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 3 0 0 0 0 0 2 0 0 1 1 0 0 0 0 0 0 0 0 0 11 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28322() 51 0 1 1 0 2 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33635() 1 1 2 3 0 0 0 0 0 0 0 0 0 14 18 0 3 1 0 0 0 0 0 9 0 0 3 0 0 0 2 0 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG25664() 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3981(Predicted acetyltransferase) 37 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 6 2 0 0 0 0 0 0 0 9 0 0 0 0 1 0 0 0 0 0 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11804() 3 4 1 0 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2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 3 0 6 0 0 0 0 0 22 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3171(Uncharacterized protein conserved in bacteria) 59 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12819() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09321() 3 3 4 3 0 0 0 0 0 0 0 0 0 1 0 2 2 1 3 1 6 1 6 0 1 12 0 2 1 0 2 0 0 0 0 5 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG5542(Predicted integral membrane protein) 0 0 3 0 0 1 1 0 0 0 0 0 2 0 0 0 6 1 0 0 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 2 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08939() 1 1 1 0 0 0 0 0 1 0 0 3 1 6 0 0 1 2 3 0 2 2 2 1 0 1 0 0 0 1 0 0 0 0 0 0 4 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06450() 30 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 10 3 0 0 0 1 2 1 0 5 0 0 0 0 0 1 1 0 2 4 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11736() 0 0 0 1 1 0 1 4 0 0 0 0 4 0 0 0 0 0 0 0 1 0 3 1 2 11 0 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COG4458(Uncharacterized protein conserved in bacteria, putative virulence factor) 4 0 0 0 0 0 0 0 0 0 0 0 0 2 2 1 0 4 0 0 0 0 2 0 0 0 0 0 0 0 0 3 3 0 2 1 0 36 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20786() 3 1 5 7 1 1 2 1 0 0 2 1 0 0 0 0 0 0 0 1 0 0 4 0 0 2 0 1 0 0 2 2 3 0 8 7 0 0 4 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5024(Cyclin) 0 0 2 2 3 6 1 0 0 0 0 1 0 3 2 0 0 0 0 0 0 0 5 0 0 19 3 0 0 6 1 0 1 0 0 0 2 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06761(Protein involved in DNA replication termination) 56 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06059(Cytochrome c protein) 51 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3566(Uncharacterized protein conserved in bacteria) 1 0 0 0 0 0 0 3 0 0 0 0 1 0 0 0 0 1 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 46 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11105() 3 1 1 1 0 1 0 0 0 0 0 0 3 12 0 3 0 0 2 1 0 0 0 0 0 0 2 0 0 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and glucuronate interconversions) 1 1 2 0 0 1 0 4 0 0 0 3 0 0 0 1 0 0 2 1 0 0 3 0 0 1 0 0 0 1 0 2 0 0 2 2 10 21 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19862() 0 4 4 2 1 0 0 2 0 3 0 4 1 5 2 2 3 0 2 3 0 0 2 1 0 0 2 0 1 0 0 6 0 2 2 3 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2004(Ribosomal protein S24E) 0 2 3 1 0 1 0 0 0 0 0 0 0 3 0 0 0 0 2 3 1 9 5 3 0 0 0 0 3 2 3 2 3 0 0 2 0 0 0 3 2 2 0 0 0 0 0 0 0 0 0 2 0 0 0 4 NOG06568() 47 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10809() 9 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 4 0 0 0 0 0 0 0 0 0 1 0 7 0 0 0 0 0 17 17 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1151(6Fe-6S prismane cluster-containing protein) 49 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 4 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4634(Uncharacterized protein conserved in bacteria) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19696() 1 1 0 0 0 0 0 0 0 0 0 0 3 2 0 0 0 0 4 2 0 0 0 1 0 0 2 3 0 0 0 3 3 1 8 3 0 4 5 9 1 3 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG13014() 0 0 13 2 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 4 6 2 4 0 8 3 0 0 0 2 0 0 0 6 2 0 1 2 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG23874() 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07933() 1 3 2 4 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 2 1 0 0 3 3 1 0 0 6 1 0 3 5 0 12 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16097() 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3500(Phage protein D) 9 1 1 1 0 0 0 0 3 0 3 2 0 0 0 1 0 2 0 0 0 0 4 2 0 0 2 1 0 0 0 3 1 0 2 4 7 8 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG31359() 9 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 0 2 0 1 0 0 1 0 0 0 0 20 21 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG17682() 59 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 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1 1 0 0 3 0 0 0 1 4 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG11754(Type III restriction enzyme) 0 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 1 0 0 0 0 2 1 0 0 1 0 0 0 0 4 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30398() 0 0 3 0 0 0 0 1 1 0 0 0 0 1 0 1 0 2 2 0 3 3 2 0 0 11 1 0 1 3 0 0 0 2 0 3 3 15 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 COG3442(Predicted glutamine amidotransferase) 1 0 1 0 0 1 3 4 0 2 0 0 0 1 0 0 7 1 5 0 2 0 0 4 0 4 0 2 1 0 3 1 2 4 2 1 1 0 4 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG31724() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30458() 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17160() 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 2 1 0 0 1 0 0 2 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2312(Erythromycin esterase homolog) 2 0 2 0 1 1 0 0 0 0 0 0 4 0 0 1 1 0 2 0 1 0 0 5 0 2 0 0 0 0 0 0 3 2 2 0 2 24 1 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14027(Tonb-Dependent receptor) 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22700() 1 0 2 4 2 0 0 3 2 1 1 1 0 2 4 1 0 0 0 1 2 0 5 2 1 0 1 1 0 1 1 5 3 0 6 3 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG16260() 1 1 9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 9 14 2 4 0 2 2 1 1 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 NOG13438() 50 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17277() 50 1 5 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19150() 0 0 3 2 0 0 3 0 0 0 2 5 0 2 0 1 2 1 2 0 0 0 0 1 1 0 0 0 0 0 0 4 2 3 6 10 1 0 2 3 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18659() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21808() 5 0 1 3 0 0 0 6 0 0 1 0 0 1 0 0 1 0 2 2 0 2 0 3 0 1 1 0 0 3 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17326() 34 4 3 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 3 2 0 1 2 0 1 0 0 0 1 0 3 3 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36697() 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16546() 10 1 1 0 2 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 1 1 0 0 4 0 1 0 4 1 0 0 1 0 20 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG4729(Uncharacterized conserved protein) 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 7 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38731() 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13524() 13 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 3 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 35 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2747(Negative regulator of flagellin synthesis (anti-sigma28 factor)) 47 6 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14868() 2 2 3 3 2 0 0 0 3 3 0 1 1 3 0 1 2 0 2 1 0 0 1 0 1 0 4 0 1 2 0 1 3 0 4 6 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 3 NOG36036() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 3 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 2 0 47 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30156() 59 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25135() 1 2 3 1 1 0 2 2 0 0 0 1 2 0 2 1 0 0 0 1 3 0 0 0 0 6 0 0 0 0 0 0 1 2 0 2 4 22 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19806() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14018(Transcriptional regulator protein) 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29410() 0 0 1 2 0 2 0 2 7 0 0 1 2 2 0 0 3 0 2 1 0 0 1 1 0 2 2 0 1 0 2 2 3 0 3 13 0 0 2 0 1 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 NOG14404() 44 1 1 1 0 0 0 0 0 0 0 0 2 2 2 0 0 0 0 1 0 2 1 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13776() 31 5 2 4 0 0 0 1 0 0 0 1 0 2 0 0 0 0 0 0 0 0 2 1 2 0 0 0 1 0 2 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG37243(Protein involved in photosynthesis) 12 3 0 0 1 1 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 6 3 0 2 1 0 0 23 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09051() 1 8 8 4 0 0 0 0 1 0 0 0 0 3 0 0 8 0 2 0 4 0 2 2 2 0 0 2 0 0 0 0 0 0 0 1 4 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18000(ABC transporter, periplasmic protein) 54 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21287() 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 4 0 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5459(Predicted rRNA methylase) 0 11 8 5 0 0 0 0 0 0 0 2 0 2 0 0 3 3 1 0 0 0 2 0 0 9 2 0 0 1 0 2 0 0 0 3 2 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19141() 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13250() 11 4 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0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4544(Uncharacterized conserved protein) 3 2 0 1 0 0 0 2 1 0 0 1 0 0 0 0 2 1 4 0 2 0 0 1 2 3 1 0 0 0 0 1 3 2 6 1 1 9 5 1 0 2 0 1 2 0 0 0 0 0 0 0 0 0 0 0 NOG11900() 1 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 3 51 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18572() 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3400(Uncharacterized protein conserved in bacteria) 4 1 0 0 0 0 2 1 0 0 0 2 0 8 0 0 2 5 1 0 0 0 1 0 3 0 1 0 0 0 2 0 2 0 2 4 0 5 2 0 0 4 0 0 0 0 0 0 0 0 0 4 0 0 0 3 NOG19146() 0 0 1 0 0 0 1 0 1 2 0 2 2 0 0 2 0 2 2 0 2 0 1 0 0 5 0 1 2 0 1 2 0 0 4 1 2 13 0 8 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2846(Regulator of cell morphogenesis and NO signaling) 28 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 2 1 3 3 1 1 0 0 0 0 0 0 2 2 2 0 0 2 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10036(Transcriptional regulator protein) 8 3 2 1 0 1 1 0 1 0 1 1 0 3 0 0 0 0 1 0 0 0 1 0 1 0 0 0 0 0 0 3 4 0 2 2 2 13 4 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25303(Alginate lyase precursor) 53 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15809() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09615() 3 1 3 2 0 0 0 2 2 2 0 0 0 0 1 3 6 3 1 0 0 2 0 0 0 4 0 0 0 0 0 0 1 0 2 6 10 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG22940() 1 1 2 0 0 0 0 1 0 1 0 0 0 5 2 1 2 0 0 0 0 0 2 2 0 1 4 1 2 1 1 6 5 0 1 4 0 7 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG38990() 4 4 1 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 6 3 5 4 0 0 0 1 7 1 2 2 0 6 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 NOG09444(Allophycocyanin, alpha protein) 6 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 1 0 1 0 5 2 2 0 0 0 23 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3421(Uncharacterized protein conserved in bacteria) 2 3 0 1 0 0 0 0 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0 0 0 0 0 0 0 0 0 NOG19151() 0 0 0 0 8 0 2 6 0 0 0 1 4 7 1 0 0 0 1 2 0 1 3 0 0 4 1 3 1 0 0 0 1 0 4 0 2 2 2 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG14466(50S ribosomal protein) 0 2 1 0 5 1 2 2 1 0 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 11 4 4 6 1 6 0 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16583() 4 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 3 2 8 0 0 2 1 0 3 2 0 0 0 1 0 17 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5385(Uncharacterized protein conserved in bacteria) 0 0 0 0 1 1 0 0 0 0 0 0 1 16 0 3 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 3 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19685() 3 1 1 1 1 1 1 0 0 5 3 0 0 2 0 1 0 0 0 1 0 0 5 0 0 0 0 0 1 0 0 1 0 0 4 0 0 23 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3247(Uncharacterized conserved protein) 3 0 0 3 0 0 0 0 0 0 0 1 1 5 0 0 0 0 1 0 0 0 0 0 0 2 3 0 1 0 0 0 0 0 0 0 2 35 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18991(Dioxygenase) 5 0 4 2 0 1 0 0 1 4 0 1 0 1 0 1 2 0 0 3 1 0 1 1 1 0 1 0 1 2 0 2 1 0 0 1 0 14 1 5 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG08659() 0 0 0 2 0 1 0 0 0 0 0 3 0 5 0 0 2 5 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG24262(Radical SAM protein) 4 4 3 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 6 2 1 0 1 0 0 2 1 0 0 4 6 0 2 2 0 0 4 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4834(Uncharacterized protein conserved in bacteria) 1 1 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 4 0 0 0 0 0 0 1 2 0 0 0 0 0 1 2 0 0 0 41 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3042(Putative hemolysin) 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25012() 0 2 1 0 0 1 0 0 1 4 6 0 0 2 0 0 6 0 3 0 0 0 0 0 2 3 0 0 0 0 0 0 1 0 2 4 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08803() 3 0 0 0 0 3 0 0 0 0 0 0 1 1 0 0 0 0 0 0 1 0 2 3 2 1 3 2 1 0 3 7 1 2 4 4 0 2 1 6 1 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 COG5518(Bacteriophage capsid portal protein) 12 0 0 0 1 0 0 0 0 0 7 0 0 0 0 0 1 0 1 0 0 0 0 0 0 26 2 0 0 0 0 0 1 0 0 0 1 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28205() 26 0 0 0 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NOG16021() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 9 0 0 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28570() 3 1 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1 1 1 4 0 2 0 0 1 0 5 0 0 0 0 1 19 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16559() 6 0 0 1 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 1 0 0 2 0 3 1 1 0 0 0 25 7 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG06550() 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4691(Plasmid stability protein) 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09881() 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG12958() 5 0 0 0 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 0 0 1 0 0 3 0 4 3 0 0 0 0 17 14 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13619() 1 3 1 2 0 0 2 1 0 0 0 0 0 0 0 2 0 4 0 0 0 2 3 1 0 0 2 0 4 0 0 0 1 0 0 2 10 12 0 0 0 0 0 0 0 0 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0 0 0 0 NOG23653() 56 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19628(Response regulator receiver domain protein) 56 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14984() 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20012() 3 1 1 3 0 0 0 1 0 0 0 0 0 0 2 0 3 0 0 0 0 3 2 0 1 8 0 2 1 0 0 3 4 2 0 2 2 7 2 0 1 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 COG2510(Predicted membrane protein) 1 0 3 1 0 1 1 0 0 0 0 0 0 0 2 0 0 11 1 0 2 0 1 2 0 0 0 2 0 0 0 0 4 3 5 2 2 1 4 0 2 2 0 0 0 0 0 0 0 0 0 4 0 0 0 0 NOG11917() 27 0 0 0 0 0 0 0 0 0 1 0 0 1 3 3 5 6 1 0 0 0 0 0 0 8 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36125() 56 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14715() 3 0 0 1 0 2 0 0 3 0 2 0 0 4 0 0 0 0 2 0 2 0 1 0 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DNA repair protein (RAD52 pathway)) 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 51 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36040() 52 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG07971() 0 0 0 1 0 0 0 0 1 1 2 2 0 3 0 2 5 10 3 1 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 3 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21146(Merr-Family protein) 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26043() 0 3 21 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 1 0 6 0 3 3 0 0 0 1 2 2 2 0 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19671() 0 1 0 0 0 0 0 3 0 0 0 0 4 4 0 0 0 0 1 0 2 0 0 1 1 0 1 2 0 0 0 2 1 4 5 1 2 16 0 4 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG33516() 0 1 15 5 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 4 6 0 0 0 6 0 0 2 0 0 0 2 2 4 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19971() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 52 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0 0 0 0 0 0 0 0 0 0 0 0 1 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16437() 9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 7 0 1 0 0 0 19 11 1 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG19716(Cobalamin biosynthesis protein) 1 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 0 4 6 7 8 4 1 0 3 9 3 1 0 0 0 1 0 0 0 0 0 0 0 0 0 1 COG1515(Deoxyinosine 3endonuclease (endonuclease V)) 6 1 15 2 0 1 0 0 0 0 0 0 0 0 0 0 3 0 1 0 1 6 2 0 1 0 0 0 0 2 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG11857() 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3055(Uncharacterized protein conserved in bacteria) 0 4 2 3 2 1 0 0 1 0 0 0 0 2 0 0 1 0 0 0 2 0 1 0 0 5 0 5 0 0 0 0 0 0 0 0 2 20 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG10063() 1 0 0 0 0 0 0 6 0 0 10 0 0 5 2 1 2 0 5 0 0 0 3 0 2 0 0 0 0 4 0 2 0 0 0 2 8 1 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG25244(2Og-Fe(Ii) oxygenase) 44 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 1 0 2 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17889() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14084() 3 0 3 4 0 0 0 0 0 0 3 0 0 1 2 1 0 1 0 0 0 6 2 3 0 0 1 2 0 1 0 1 2 2 8 2 0 2 1 1 0 2 0 0 0 0 0 0 0 0 0 2 0 0 0 0 NOG08841() 41 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 5 6 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23377() 0 0 0 0 1 0 1 4 0 0 0 0 0 4 0 0 3 0 1 1 0 1 1 0 2 3 3 2 0 1 2 2 5 2 8 2 0 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG19098() 1 0 3 0 0 2 0 0 2 0 6 0 1 3 0 1 0 2 1 0 0 0 1 0 0 0 0 0 0 0 3 4 2 0 4 7 0 6 4 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28438() 7 0 0 1 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 1 3 0 0 0 0 0 0 0 2 0 5 1 0 0 0 0 24 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20283() 50 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2384(Predicted SAM-dependent methyltransferase) 40 1 3 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08696() 7 0 0 0 0 0 0 0 0 0 1 0 0 3 2 1 11 8 1 0 1 0 0 0 0 9 0 0 0 0 0 0 0 0 0 10 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19294() 2 2 2 4 0 0 0 0 0 0 0 0 0 2 6 0 0 0 0 1 6 1 1 1 0 3 0 0 0 0 0 4 0 2 4 3 1 10 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG11854() 54 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG19775() 2 1 3 2 0 1 1 0 0 0 1 2 0 0 0 0 2 0 0 0 0 0 0 3 0 5 0 0 1 0 4 0 2 0 2 4 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG25492() 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1969(Ni,Fe-hydrogenase I cytochrome b subunit) 40 0 0 0 0 0 0 0 0 0 0 2 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20035(Acid phosphatase homologues) 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG30345() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 0 49 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13426() 14 0 1 0 1 0 0 0 1 0 1 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 10 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17327() 4 4 7 7 0 0 0 0 0 0 0 0 0 0 10 0 2 0 0 2 3 0 1 2 0 5 0 1 0 0 0 0 0 0 0 3 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13825() 0 2 3 1 1 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 4 0 1 3 1 2 0 3 6 1 3 3 0 0 3 0 0 0 4 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 6 COG3169(Uncharacterized protein conserved in bacteria) 30 0 1 0 0 0 0 0 0 0 0 0 0 0 2 1 5 0 0 0 0 0 0 0 0 15 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18376() 2 1 5 3 0 1 0 0 1 1 0 0 0 5 0 0 5 2 0 1 2 1 0 0 0 4 0 1 1 0 0 0 4 2 0 2 1 5 0 0 1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG22140() 22 0 0 2 0 0 0 0 0 0 4 0 0 1 2 5 0 0 4 3 0 0 1 0 0 0 0 0 0 0 0 2 1 2 2 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4255(Uncharacterized protein conserved in bacteria) 12 0 2 0 0 0 0 0 0 0 2 0 0 5 2 0 8 6 2 0 0 0 0 0 0 11 0 0 1 0 2 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG08665() 53 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26052() 2 3 1 8 0 0 0 10 0 1 0 2 0 0 0 1 0 0 0 2 0 1 0 2 3 0 0 2 2 0 0 0 0 2 4 5 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36390() 1 3 0 0 0 0 0 4 0 3 0 0 0 0 4 0 4 0 3 0 0 0 2 2 1 0 3 0 1 3 1 4 0 0 0 3 3 1 3 4 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG17083() 45 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22976() 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11044() 2 0 1 0 0 0 0 0 2 0 2 0 0 2 0 3 5 6 4 0 0 2 0 0 0 5 0 0 0 0 0 4 1 0 0 4 0 6 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11634() 0 0 0 1 0 0 0 2 0 0 0 0 2 0 6 0 1 0 0 0 0 0 1 0 2 1 0 0 0 0 0 0 0 0 4 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG13702() 1 0 0 0 6 0 4 2 5 0 0 5 0 1 0 0 0 3 2 0 2 0 1 0 2 0 0 2 1 0 0 0 1 0 2 1 1 12 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16142() 0 5 0 17 16 1 0 1 0 0 0 0 4 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 3 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15758() 2 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 10 2 0 0 0 0 33 4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG12233() 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 3 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG36948() 0 0 3 4 1 0 3 4 1 0 2 0 0 0 0 0 0 0 2 2 0 2 2 2 3 0 3 0 1 1 0 3 0 0 0 5 0 5 0 2 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG08844() 54 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG20033(BACTERIOPHAGE protein) 2 1 0 0 1 0 0 3 0 0 1 2 5 2 2 4 0 3 3 2 0 0 1 0 0 2 2 0 1 0 0 0 3 0 0 4 0 6 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG06015() 53 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21662() 10 0 11 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 4 2 4 0 3 5 2 2 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26480(Lipoprotein) 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18304() 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11086(Acetyltransferase) 48 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3318(Predicted metal-binding protein related to the C-terminal domain of SecA) 12 0 0 0 0 0 0 1 0 1 0 1 0 1 0 1 5 1 0 0 0 0 0 1 0 3 0 0 2 1 0 0 2 1 4 1 11 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 COG2731(Beta-galactosidase, beta subunit) 45 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG11885() 4 0 0 0 0 0 0 0 0 0 0 0 0 3 4 0 13 10 2 0 0 0 2 0 0 9 3 0 0 1 1 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG35136() 6 0 0 1 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 1 0 2 0 0 0 4 1 0 0 0 0 21 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16473(Methylamine utilization protein) 6 3 19 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 3 4 4 1 0 0 0 0 2 1 0 1 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG18248(Metallo-Beta-Lactamase) 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13996(4-Oxalocrotonate tautomerase) 32 1 0 0 0 1 0 2 0 2 0 0 1 6 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG16687() 1 0 3 0 0 0 0 3 3 0 0 7 0 10 0 5 2 6 7 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22464() 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG21651() 3 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 8 3 0 0 0 0 19 13 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5581(Predicted glycosyltransferase) 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15924() 3 7 2 2 2 0 0 0 0 2 0 0 0 9 0 0 3 0 1 0 0 0 2 1 3 3 0 0 0 0 0 1 4 4 0 0 0 0 0 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 2 COG2404(Predicted phosphohydrolase (DHH superfamily)) 0 1 1 0 1 1 0 2 2 0 0 0 2 2 0 0 6 0 3 2 0 0 4 2 3 10 0 0 0 0 0 0 0 0 0 5 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG22797(Regulator protein) 9 3 0 0 0 0 0 0 0 0 4 0 0 3 2 4 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 22 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG5330(Uncharacterized protein conserved in bacteria) 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 3 0 3 0 0 0 0 0 0 3 0 0 0 0 0 2 0 0 0 0 7 32 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG19667() 1 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 0 4 4 5 16 3 1 2 2 5 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 NOG14642() 0 1 5 1 0 0 0 0 1 1 0 2 4 2 0 0 0 0 0 0 3 3 1 2 1 0 0 2 1 0 1 1 2 0 4 6 0 8 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG3174(Predicted membrane protein) 22 1 0 0 0 0 0 0 0 0 0 0 0 1 2 0 1 2 0 0 0 0 0 0 0 8 1 0 0 0 0 0 0 0 0 2 3 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4575(Uncharacterized conserved protein) 42 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG13267(Nitrogen fixation protein nifQ) 51 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG28207() 0 0 1 0 0 0 1 0 3 0 0 0 0 0 2 2 2 2 0 1 0 5 0 0 0 5 0 0 0 0 1 1 0 0 2 8 1 9 4 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14921() 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1415(Uncharacterized conserved protein) 1 1 7 4 1 0 0 0 0 0 0 0 0 6 2 0 0 0 3 0 2 2 3 1 0 0 1 0 0 0 0 2 4 0 2 3 4 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 NOG35808() 2 6 1 2 0 0 1 2 1 0 0 0 0 0 0 1 0 0 0 0 2 1 2 2 0 2 2 2 3 0 2 2 2 0 8 0 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 COG3831(Uncharacterized conserved protein) 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG17997() 50 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG38630() 7 0 0 0 2 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 6 0 0 2 0 6 1 0 0 1 0 1 0 0 0 0 0 19 6 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG14832() 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG15902() 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 11 6 0 0 0 0 0 0 1 9 0 0 0 0 0 0 0 0 0 0 1 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG10841(Allophycocyanin protein) 5 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 2 2 0 1 0 4 0 0 2 0 0 30 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG29918() 54 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG26482() 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2524(Predicted transcriptional regulator, contains C-terminal CBS domains) 5 2 3 6 1 0 0 5 0 0 0 0 0 0 2 1 4 0 1 0 0 1 3 3 0 0 1 0 3 1 0 1 0 0 0 6 2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18986() 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 3 0 33 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 COG2056(Predicted permease) 42 1 0 0 0 0 0 0 0 0 0 4 0 0 0 4 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG2229(Predicted GTPase) 2 8 6 5 0 0 4 3 2 0 0 2 0 0 0 0 0 0 1 2 1 0 7 0 0 0 0 0 0 0 0 0 0 0 0 2 5 0 0 2 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 NOG14952(Phosphoesterase, PA-phosphatase) 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG33156() 8 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 2 0 2 27 6 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19313() 0 0 0 0 0 0 0 4 2 0 2 1 0 2 2 0 2 0 3 0 1 3 2 1 0 11 0 0 0 0 0 0 1 2 2 2 3 1 2 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 4 COG4130(Predicted sugar epimerase) 0 3 2 4 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 2 1 3 0 0 0 1 1 0 3 0 4 8 4 2 2 3 5 0 3 0 0 0 0 0 0 0 0 0 1 0 0 0 1 NOG19401(Protein ThiS) 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG23398() 1 1 6 2 0 0 0 0 0 2 1 0 0 2 0 0 1 0 3 1 0 2 1 0 3 2 0 0 1 3 0 2 0 0 0 2 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 NOG09889() 47 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG1659(Uncharacterized protein, linocin/CFP29 homolog) 51 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09691() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14358(Transcriptional regulator protein) 1 1 2 1 0 2 1 0 0 2 0 2 0 1 2 1 0 0 0 0 1 2 3 1 0 1 0 1 1 0 0 1 0 0 0 2 1 18 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 NOG18068() 1 0 0 0 0 0 0 2 2 0 0 0 0 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1 2 2 0 2 1 1 0 2 1 2 0 0 0 0 0 0 2 2 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG34854() 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 7 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG4790(Type III secretory pathway, component EscR) 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 4 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG14783() 52 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG16319() 0 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 8 0 3 6 9 0 1 0 5 3 7 3 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG13315() 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG17736() 17 0 1 1 8 0 0 2 0 0 1 0 0 5 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 14 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG19570() 0 0 0 0 0 0 0 2 0 0 0 0 2 3 0 0 0 0 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 2 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 COG3458(Acetyl esterase (deacetylase)) 1 6 5 6 0 0 0 0 2 0 0 0 0 0 0 0 2 2 0 0 0 4 4 3 0 7 0 0 0 1 0 1 2 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 NOG33746() 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG06111() 0 0 0 0 0 0 0 0 1 4 0 0 0 4 0 0 0 0 0 0 0 0 0 0 1 0 3 4 0 0 0 0 0 2 4 2 0 25 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG18593() 42 7 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NOG09429(Phycobilisome core component protein) 5 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 2 0 0 1 0 0 0 2 0 0 0 0 0 19 13 1 0 0 0 0