README file for the interaction data The columns are tab-separated and are ordered as follows: Column 1: Interaction ID. This is a number assigned to each interaction randomly. Column 2: Protein ID of the first protein participating in the interaction (Protein A) Column 3: Protein ID of the second protein participating in the interaction (Protein B) Column 4: Type of interaction between the two proteins (which can be transient or permanent). Column 5 and subsequent columns: These column list the interface residues between these proteins in the following way (different fields are separated by ';'): First entry is the PDB ID of Protein A as it occurs in the complex followed by the corresponding chain (PDBID_chain). Second entry is the PDB ID of Protein B as it occurs in the complex followed by the corresponding chain (PDBID_chain). Third entry is the list of residues from Protein A that form the interface (residue IDs are separated by commas). Fourth entry is the list of residues from Protein B that form the interface (residue IDs are separated by commas). Please note that this for this file, we used a relaxed cutoff of 3 Angstrom to define interface (ie., a residue from a protein formed the interface if it came nearer than 3 Ang to any residue in the other protein). This cutoff does not affect our results as we do not use the interface in any of our calculations or results. We provide the interface residues as an additional piece of data. Due to this relaxed cutoff, some of the pairs dont have any residue listed as the interface.