G_Prot G_mRNA w_Prot w_mRNA 1 Genome +100% -100% +100% -100% Translatome (protein population) (gene population) Gene set Enrichments m(F, [ 1, G_mRNA]) D(F, [w_Prot, G_Prot ], [1, G_mRNA]) D(F, [w_mRNA, G_mRNA], [1, G_mRNA]) Greenbaum et al - Figure 1 Transcriptome (mRNA population) ? ?