Assessing the results of genomic experiments |
Hypothetical array experiment |
Transformation from continuous to discrete, binary values |
Sensitivity & specificity |
Positive predictive value |
Expansion to whole genome |
Change in positive pre-dictive value |
No information on negative experimental outcomes |
The correct out- come is only known for a subset of the experiments |
Positive predictive value as a function of sensitivity when expanding from small-scale to large-scale |